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EBI DbfetchID X72585; SV 1; linear; genomic DNA; STD; PRO; 7827 BP. XX AC X72585; XX DT 19-MAR-1993 (Rel. 35, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 14) XX DE K.aerogenes plasmid R751 genes from integron element XX KW DHFR gene; dihydrofolate reductase; int gene; integrase; invertase; KW NTP-binding protein; qacE gene; resolvase; tniA gene; tniB gene; tniC gene; KW transposase. XX OS Klebsiella aerogenes OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Klebsiella. OG Plasmid R751 XX RN [2] RP 1-7827 RA Sundstroem L.; RT ; RL Submitted (10-MAR-1993) to the EMBL/GenBank/DDBJ databases. RL L. Sundstroem, Uppsala University, Dept of Pharmaceutical Biosciences, RL Section for Microbiology, P.O. Box 581, Biomedicum, 751 23 Uppsala, SWEDEN XX RN [3] RX PUBMED; 8195081. RA Radstrom P., Skold O., Swedberg G., Flensburg J., Roy P.H., Sundstrom L.; RT "Transposon Tn5090 of plasmid R751, which carries an integron, is related RT to Tn7, Mu, and the retroelements"; RL J. Bacteriol. 176(11):3257-3268(1994). XX FH Key Location/Qualifiers FH FT source 1..7827 FT /organism="Klebsiella aerogenes" FT /plasmid="R751" FT /map="31-39 kB" FT /mol_type="genomic DNA" FT /clone_lib="pLKO603" FT /db_xref="taxon:28451" FT misc_feature <1..213 FT /note="right integron surrounding:different from the FT corresponding sequences in Tn21-Tn5086 and in pLMO20" FT repeat_region 214..238 FT /rpt_type=INVERTED FT misc_feature 214..2891 FT /note="right 2.7 kb conserved region, identical to the FT integrons of Tn5086-Tn21" FT misc_feature 214..7613 FT /note="integron" FT -35_signal 262..267 FT -10_signal 284..289 FT RBS 343..351 FT CDS 355..2034 FT /transl_table=11 FT /gene="tniA" FT /product="transposase" FT /db_xref="GOA:Q48382" FT /db_xref="InterPro:IPR001584" FT /db_xref="InterPro:IPR012337" FT /db_xref="InterPro:IPR015378" FT /db_xref="UniProtKB/TrEMBL:Q48382" FT /protein_id="CAA51175.1" FT /translation="MATDTPRIPEQGVATLPDEAWERARRRAEIISPLAQSETVGHEAA FT DMAAQALGLSRRQVYVLIRRARQGSGLVTDLVPGQSGGGKGKGRLPEPVERVIHELLQK FT RFLTKQKRSLAAFHREVTQVCKAQKLRVPARNTVALRIASLDPRKVIRRREGQDAARDL FT QGVGGEPPAVTAPLEQVQIDHTVIDLIVVDDRDRQPIGRPYLTLAIDVFTRCVLGMVVT FT LEAPSAVSVGLCLVHVACDKRPWLEGLNVEMDWQMSGKPLLLYLDNAAEFKSEALRRGC FT EQHGIRLDYRPLGQPHYGGIVERIIGTAMQMIHDELPGTTFSNPDQRGDYDSENKAALT FT LRELERWLTLAVGTYHGSVHNGLLQPPAARWAEAVARVGVPAVVTRATSFLVDFLPILR FT RTLTRTGFVIDHIHYYADALKPWIARRERWPSFLIRRDPRDISRIWVLEPEGQHYLEIP FT YRTLSHPAVTLWEQRQALAKLRQQGREQVDESALFRMIGQMREIVTSAQKATRKARRDA FT DRRQHLKTSARPDKPVPPDTDIADPQADNLPPAKPFDQIEEW" FT RBS 2024..2032 FT CDS 2037..2945 FT /transl_table=11 FT /gene="tniB" FT /product="NTP-binding protein" FT /db_xref="GOA:Q48383" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR008868" FT /db_xref="UniProtKB/TrEMBL:Q48383" FT /protein_id="CAA51176.1" FT /translation="MDEYPIIDLSHLLPAAQGLARLPADERIQRLRADRWIGYPRAVEA FT LNRLEALYAWPNKQRMPNLLLVGPTNNGKSMIVEKFRRTHPASSDADQEHIPVLVVQMP FT SEPSVIRFYVALLAAMGAPLRPRPRLPEMEQLALALLRKVGVRMLVIDELHNVLAGNSV FT NRREFLNLLRFLGNELRIPLVGVGTRDAYLAIRSDDQLENRFEPMMLPVWEANDDCCSL FT LASFAASLPLRRPSPIATLDMARYLLTRSEGTIGELAHLLMAAAIVAVESGEEAINHRT FT LSMAVYTGPSERRRQFERELM" FT CDS 2672..4159 FT /transl_table=11 FT /gene="ORF6" FT /db_xref="InterPro:IPR009492" FT /db_xref="UniProtKB/TrEMBL:Q48384" FT /protein_id="CAA51177.1" FT /translation="MGGQRRLLLTAGQLRRFAPAAPAFPNCHAGHGSLPAHTQRGHHRG FT TGALADGGGHRRRGERRGSDQPSHTQHGRLHRTQRAAAAIRAGTDVKPAPRWPLHPAPK FT EGEALSSWLNRVALCYHMEEPDLLEHDLGHGQVDDLDTAPPLSLLALLSQRSGIELDRL FT RCMSFAGWVPWLLDSLDDQIPDALETYAFQLSVLLPRLRRKTRSITSWRAWLPSQPINR FT ACPLCLSDPENQAVLLAWKLPLMLSCPLHGCWLESYWGVPGRFLGWENADAEPRTASDA FT IAAMDQRTWQALTTGHVELPRRRIHAGLWFRLLRTLLDELNTPLSACGTCAGYPRQVWE FT GCGHPLRAGQSLWRPYETLNPIVRLQMLEAAATAISLIEVRDISPPGEQAKLFWSEPQT FT GFTSGLPTKAPKPEPINHWQRAVQAIDEAIIEARHNPETARSLFALASYGRRDPASLER FT LRATFVKEGIPPEFLSHYLPDAPFACLKQNDGLSDKF" FT misc_feature 2891..2892 FT /note="divergence point between R751, Tn5086 and Tn21" FT misc_feature 2892..5143 FT /note="right variable segment 2.3 kb replaced with other FT segments carrying sulI in in Tn21 and Tn5086" FT RBS 4212..4215 FT CDS 4221..4844 FT /transl_table=11 FT /gene="tniC" FT /product="invertase" FT /db_xref="GOA:Q48385" FT /db_xref="HSSP:2RSL" FT /db_xref="InterPro:IPR006118" FT /db_xref="InterPro:IPR006119" FT /db_xref="InterPro:IPR006120" FT /db_xref="UniProtKB/TrEMBL:Q48385" FT /protein_id="CAA51178.1" FT /translation="MLIGYMRVSKADGSQSTNLQRDALIAAGVSLAHLYEDLASGRRDD FT RPGLAACLKALREGDTLIVWKLDRLGRDLRHLINTVHDLTARSVGLKVLTGHGAAVDTT FT TAAGKLVFGIFAALAEFERELISERTVAGLISARARGRKGGRPFKMTAAKLRLAMASMG FT QPETKVGDLCEELGITRQTLYRHVSPKGELRPDGVKLLSLGSAA" FT stem_loop 4962..5031 FT /note="AT rich" FT /experiment="experimental evidence, no additional details FT recorded" FT misc_feature 5084..5524 FT /note="sequence of reference [3] Paulsen et al. accession FT number X68232" FT misc_feature 5143..5144 FT /note="insertion point for sulI in Tn21-Tn5086 [3]" FT misc_feature complement(5143..5144) FT /note="insertion point for sulI in Tn21-Tn5086 [3]" FT misc_feature 5144..5534 FT /note="middle conserved region: the conserved segment down FT stream of the variable cassettes [1,3]" FT CDS complement(5093..5425) FT /transl_table=11 FT /gene="qacE" FT /product="multidrug exporter" FT /db_xref="GOA:P0AGD0" FT /db_xref="InterPro:IPR000390" FT /db_xref="UniProtKB/Swiss-Prot:P0AGD0" FT /protein_id="CAA51179.1" FT /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY FT FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIVSGVVVLNLL FT SKASAH" FT misc_feature complement(5054..5534) FT /note="qacE cassette [1]" FT repeat_region complement(5581..5590) FT /rpt_family="A'" FT CDS complement(5530..5820) FT /transl_table=11 FT /gene="ORFD" FT /db_xref="InterPro:IPR010416" FT /db_xref="UniProtKB/TrEMBL:Q79AH2" FT /protein_id="CAA51180.1" FT /translation="MFIQTAFSFSNAVQRWVCRFSGLRLVALRWFVVFLASGPCVASAS FT SYFFRSAVPPRWHRAFSQLAPVAKLRLSVLASGSNISVKPTRILRSAYLAR" FT repeat_region complement(5845..5854) FT /rpt_family="A" FT misc_feature 5894..5953 FT /note="segments missing in the related dhfrIIb cassette of FT IncW-plasmid R388" FT repeat_region complement(5898..5905) FT /rpt_family="A'" FT CDS complement(5957..6193) FT /transl_table=11 FT /gene="dhfrIIc" FT /product="dihydrofolate reductase type IIc" FT /db_xref="GOA:P05794" FT /db_xref="InterPro:IPR008990" FT /db_xref="InterPro:IPR009159" FT /db_xref="UniProtKB/Swiss-Prot:P05794" FT /protein_id="CAA51181.1" FT /translation="MDQHNNGVSTLVAGQFALPSHATFGLGDRVRKKSGAAWQGQVVGW FT YCTKLTPEGYAVESESHPGSVQIYPVAALERVA" FT misc_feature 6235..6236 FT /note="segment of 46 bp of the dhfrIIb cassette missing in FT this sequence" FT misc_feature 6246..6255 FT /note="segments missing in the related dhfrIIb cassette of FT IncW-plasmid R388" FT misc_feature 6259..7613 FT /note="the left conserved segment of 1.4 kb in Tn21-Tn5086 FT commonly regarded as the constant sequence upstream of the FT cassettes" FT misc_feature complement(5535..6262) FT /note="left variable region cassettes" FT misc_feature complement(5855..6262) FT /note="dhfrIIc cassette" FT repeat_region complement(6255..6262) FT /rpt_family="A" FT variation 6375 FT /replace="cccc" FT /note="in Tn21: affects -35 to -10 distance of a potential FT promoter active in Tn21" FT CDS 6398..7411 FT /transl_table=11 FT /gene="int" FT /product="integrase" FT /db_xref="GOA:Q79AH1" FT /db_xref="HSSP:1A0P" FT /db_xref="InterPro:IPR002104" FT /db_xref="InterPro:IPR004107" FT /db_xref="InterPro:IPR010998" FT /db_xref="InterPro:IPR011010" FT /db_xref="InterPro:IPR011946" FT /db_xref="InterPro:IPR013762" FT /db_xref="UniProtKB/TrEMBL:Q79AH1" FT /protein_id="CAA51182.1" FT /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVNWVRAFI FT RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI FT GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG FT TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR FT AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH FT SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER" FT variation 6487 FT /replace="c" FT /note="in Tn21-Tn5086" FT -10_signal complement(6485..6490) FT variation 6512 FT /replace="c" FT /note="in Tn21-Tn5086: -35 is optimal in R751" FT -35_signal complement(6508..6513) FT repeat_region 7589..7613 FT /rpt_type=INVERTED FT misc_feature 7614..>7827 FT /note="integron left surrounding:no similarity with FT sequences to the left of integron IRs in Tn21 -Tn5086, FT pLMO20, pLMO229, R388 -pSa" XX SQ Sequence 7827 BP; 1583 A; 2396 C; 2371 G; 1477 T; 0 other; ctgcagcatc gccattgccg acgatggcac caggtcgccg gcggtggcca ccgacctcga 60 gctcgcatcg ccacatccga cgatgcgcgc cggcgtcgac catcgccagg tctgacgatg 120 gcggccgccc tgccctggat ctcgcatcgc catttctggc gatgagatcc acggagcggc 180 catttagacc cgccaataac gacccggcca agatgtcatt ttcagaagac gactgcacca 240 gttgattggg cgtaatggct gttgtgcagc cagctcctga cagttcaata tcagaagtga 300 tctgcaccaa tctcgactat gctcaatact cgtgtgcacc aaagcgaggt gagcatggcg 360 acggacaccc cacggattcc agaacaaggc gtggccactc tgcctgatga ggcttgggag 420 cgtgcgcgcc gtcgtgcgga gatcatcagt ccgttggcgc agtcggagac ggtcgggcac 480 gaagcggccg atatggcggc tcaggcgctg ggcttgtctc ggcgccaggt atacgttctg 540 atccggcgtg cccggcaagg cagcggcctc gtgacggatc tggtgcccgg ccagtccggt 600 ggaggtaaag gtaaggggcg cttgccggaa ccggtcgagc gcgtcatcca cgagctactg 660 caaaagcggt tcctgaccaa gcagaagcgc agcctagcgg cctttcaccg cgaagtcact 720 caggtgtgca aggctcaaaa actgcgagtg ccggcgcgca ataccgtggc cttacggatc 780 gctagccttg acccgcgcaa ggtcatccgc cggcgggaag gccaggatgc cgctcgtgac 840 ctacaaggtg tgggcggcga gcctcctgcc gtgaccgcgc cgctggagca ggtgcagata 900 gaccatacgg tcatcgacct gatcgtggtc gatgaccgcg accggcaacc tattggccgc 960 ccgtacctga ccctcgccat cgacgtgttc acccgctgcg tgctcggcat ggtcgtcacg 1020 ctggaagcgc cgtctgccgt ttcggttggc ctgtgcctcg tgcatgtcgc ctgcgacaag 1080 cgcccttggc tggaaggact gaacgtggaa atggattggc agatgagcgg caagcccttg 1140 ctgctctacc tagacaacgc ggccgagttc aagagcgagg ccctgcgccg gggttgcgag 1200 cagcatggca tccggctgga ctatcgcccg ctgggacagc cgcactatgg cggcatcgtg 1260 gaacggatca tcggcacggc gatgcagatg attcacgacg aactgccggg aacgaccttc 1320 tccaaccctg accagcgcgg cgactacgat tccgaaaaca aggccgccct gacgctgcgc 1380 gagctagagc gctggctcac attggcggtc ggcacctacc acggttcggt gcacaacggc 1440 ctgctccaac cgccggccgc gcgctgggcc gaggccgtgg cgcgtgtcgg cgtaccggcc 1500 gtcgtcacac gcgctacttc gttcctggtc gattttctgc cgatcctccg gcgcacgctg 1560 acccgcaccg gctttgtcat cgaccacatc cactactacg ccgatgcgct caagccgtgg 1620 attgcgcggc gtgaacgctg gccgtccttt ctgatccggc gcgatccgcg cgacatcagc 1680 cgtatctggg tcctggaacc ggagggacag cattacctgg aaattcccta ccgtaccttg 1740 tcgcatccgg ctgtcaccct ctgggaacaa cggcaggcgc tggcgaaact gcggcagcaa 1800 gggcgcgaac aggtggatga gtcggcgctg ttccgcatga tcggccagat gcgtgagatt 1860 gtgaccagcg cgcagaaggc cacacgcaag gcgcggcgtg acgcggatcg ccgccagcac 1920 ctcaagacat cagctcggcc ggacaagccc gttccgccgg atacggatat tgccgacccg 1980 caggcagaca acttgccacc cgccaaaccg ttcgaccaga ttgaggagtg gtagccgtgg 2040 acgaatatcc catcatcgac ctgtcccacc tgctgccggc ggcccagggc ttggcccgtc 2100 ttccggcgga cgagcgcatc cagcgccttc gcgccgaccg ctggatcggc tatccgcgcg 2160 cagtcgaggc gctgaaccgg ctggaagccc tttatgcgtg gccaaacaag caacgcatgc 2220 ccaacctgct gctggttggc ccgaccaaca atggcaagtc gatgatcgtc gagaagttcc 2280 gccgcaccca cccggccagc tccgacgccg accaggagca catcccggtg ttggtcgtgc 2340 agatgccgtc cgagccgtcc gtgatccgct tctacgtcgc gctgctcgcc gcgatgggcg 2400 cgccgctgcg cccacgccca cggttgccgg aaatggagca actggctctg gcactgctgc 2460 gcaaggtcgg cgtgcgcatg ctggtgatcg acgagctgca caacgtgctg gccggcaaca 2520 gcgtcaaccg ccgggaattc ctcaacctgc tgcgcttcct cggcaacgaa ctgcgcatcc 2580 cgttggttgg ggtaggcacg cgcgacgcct acctagccat ccgctccgat gaccagttgg 2640 aaaatcgctt cgagccgatg atgctgccgg tatgggaggc caacgacgat tgctgctcac 2700 tgctggccag cttcgccgct tcgctcccgc tgcgccggcc ttccccaatt gccacgctgg 2760 acatggctcg ctacctgctc acacgcagcg agggcaccat aggggaactg gcgcacttgc 2820 tgatggcggc ggccatcgtc gccgtggaga gcggcgagga agcgatcaac catcgcacac 2880 tcagcatggc cgtttacacc ggacccagcg agcggcggcg gcaattcgag cgggaactga 2940 tgtgaagcct gcgccgcgct ggccgctgca tcccgccccg aaagaaggcg aggcgctgtc 3000 ctcatggctc aaccgcgtgg ccctttgcta tcacatggag gagcccgacc tgctggagca 3060 cgatcttggt cacggccagg tcgatgacct ggacaccgcg ccaccactct cgctgctggc 3120 gttgctttcc cagcggagcg gcatcgagct ggaccggctg cgctgtatga gtttcgccgg 3180 atgggtgcct tggctactgg acagccttga tgaccagatt ccagacgcct tggaaaccta 3240 tgcgtttcag ctctcggtgt tgctgccaag actccgccgt aagacgcgat ccatcacgag 3300 ctggcgtgcc tggctgccca gccagccgat aaaccgcgcc tgtccgctct gcctgagcga 3360 tccggagaac caagccgtac tgctcgcgtg gaagctgccc ctgatgctga gctgcccgct 3420 gcatggctgc tggctggaat cctattgggg cgtgccaggg cggtttctcg gttgggagaa 3480 cgccgacgcc gaaccgcgca ccgccagcga cgcgattgcg gcgatggacc agcgtacctg 3540 gcaggcactg acaaccggtc acgtggagct gccgcgccga cgcatccacg ccggattgtg 3600 gtttcgactt cttcgcacgc tgctcgatga gctgaacacc ccgctttccg cgtgcggaac 3660 ctgcgcgggg tatccccgcc aagtctggga aggctgcggg catccgctgc gtgctgggca 3720 aagtctgtgg cgaccgtatg aaaccctgaa tccgatagta cggttacaga tgctggaggc 3780 ggcggcaacg gcaatcagct tgattgaggt gagggacatc agcccgccag gcgagcaggc 3840 aaagctattc tggtccgagc cccaaaccgg gttcaccagt ggcctgccga cgaaagcgcc 3900 gaagcccgag cccatcaatc actggcagcg tgcagtccag gccatcgacg aggccatcat 3960 tgaagcgcga cacaaccccg agacggcacg ctcgctgttc gcgttggctt cctatggtcg 4020 gcgcgatccc gcttccttgg aacggttgcg cgccaccttc gtgaaggaag gcatcccgcc 4080 ggaatttctg tcacattacc tgcctgatgc accctttgca tgtcttaaac aaaatgacgg 4140 gttaagtgac aaattttgac ggatagagct ttccggctca cactgtcaca taatcgaacg 4200 tatacgtgac gggtgaaaag gtgctgatcg gctacatgcg ggtatcgaag gcggacggat 4260 cccagtccac caatttgcaa cgcgatgcgc tcatcgccgc tggtgtgagc cttgcgcacc 4320 tttacgagga tctggcctcg ggcaggcgcg atgatcgccc agggttggct gcttgcctga 4380 aggcgcttcg tgaaggggac acgctgatcg tgtggaagct cgatcggctt ggccgtgatc 4440 tgcgccacct gatcaacacc gtgcacgacc taactgcgcg tagcgtgggc ctgaaggtcc 4500 tgaccggtca cggtgcggcg gtcgacacga cgactgccgc cggcaagctt gtgttcggta 4560 tttttgccgc gctggccgag ttcgagcgtg agttgatttc cgagcgaaca gtcgctggac 4620 ttatctcggc gcgcgctcgc ggcaggaaag gggggcgccc cttcaagatg accgccgcca 4680 agctacgcct ggcgatggcc agcatggggc aaccggaaac caaggtgggc gatctctgcg 4740 aagaactcgg gattacccgg cagacgctct accggcacgt gtcgcccaag ggcgaactgc 4800 ggccagacgg cgtaaagctg ctctccctcg gttcagccgc ataaatggag gcgacctgga 4860 acggggcgct gttcagtgcg gcaacgatcc gattaccggt gtcgacccag agcagccgta 4920 gagcttttgg gaaagctgtc gttcaacgcc gagttcagcg gcagttttta agttgtgatt 4980 ttatggaata cttttgcgca gcaaaaccat aaagccgcga cttaaaaact gtccagcgca 5040 ggcacgaagt gctggagcgg tgctgcaacg acttgttaga tgactgagtt tattagtggg 5100 cacttgcttt ggaaagcaag tttaaaacta ctacaccact aactatgagc cccataccta 5160 caaagcccca cgcatcaagc ttttgcccat gaagcaacca ggcaatggct gtaattatga 5220 cgacgccgag tcccgaccag actgcataag caacaccgac agggatggat ttcagaacca 5280 gagaaagaaa ataaaatgcg atgccataac cgattatgac aacggcggaa ggggcaagct 5340 tagtaaagcc ctcgctagat tttaatgcgg atgttgcgat tacttcgcca actattgcga 5400 taacaagaaa aagccagcct ttcatgatat atctcccaat ttgtgtaggg cttattatgc 5460 acgcttaaaa ataataaaag cagacttgac ctgatagttt ggctgtgagc aattatgtgc 5520 ttagtgcatc taacgggcga ggtaagccga ccgcagaatg cgggtcggct tgaccgaaat 5580 gttagagcca gaagccaaaa cggataaccg taacttggcg acgggcgcta actgcgaaaa 5640 ggcacggtgc caccgaggcg gcacagcact acgaaaaaaa tagctgctcg cgcttgctac 5700 acaagggcca gaggccaaaa agaccacaaa ccagcgtaac gccaccaggc gaagcccaga 5760 gaaacggcaa acccagcgct gcacagcgtt tgagaaactg aatgccgttt gaataaacat 5820 gggcgaaata aaggagggtt tcagtggtac taacgctcta gctcagcggg cggcgaagcc 5880 gtccgctgga gcgaccagtt gggctgtggg cggtactgca cggcttgagc gctgagcggt 5940 gcactcaacc gtgaattcag gccacgcgtt caagcgcagc cacaggataa atctgtactg 6000 aaccggggtg agactcggac tcgacggcat agccttcagg ggtcagtttt gtgcagtacc 6060 acccgacaac ttgaccctgc caagcggcgc cagatttctt gcgcacgcga tctcccaggc 6120 caaacgtggc gtgcgatggg agcgcaaact ggccagcaac tagagtactg actccattgt 6180 tgtgttggtc catatctgac ctttcttgtg aatttcttga gatgcttgct agcccgacaa 6240 cgctgcgtcg gtgaagccca actttgtttt agggcgactg ccctgctgcg taacatcgtt 6300 gctgctccat aacatcaaac atcgacccac ggcgtaacgc gcttgctgct tggatgcccg 6360 aggcatagac tgtacaaaaa aacagtcata acaagccatg aaaaccgcca ctgcgccgtt 6420 accaccgctg cgttcggtca aggttctgga ccagttgcgt gagcgcatac gctacttgca 6480 ttacagttta cgaaccgaac aggcttatgt caactgggtt cgtgccttca tccgtttcca 6540 cggtgtgcgt cacccggcaa ccttgggcag cagcgaagtc gaggcatttc tgtcctggct 6600 ggcgaacgag cgcaaggttt cggtctccac gcatcgtcag gcattggcgg ccttgctgtt 6660 cttctacggc aaggtgctgt gcacggatct gccctggctt caggagatcg gaagacctcg 6720 gccgtcgcgg cgcttgccgg tggtgctgac cccggatgaa gtggttcgca tcctcggttt 6780 tctggaaggc gagcatcgtt tgttcgccca gcttctgtat ggaacgggca tgcggatcag 6840 tgagggtttg caactgcggg tcaaggatct ggatttcgat cacggcacga tcatcgtgcg 6900 ggagggcaag ggctccaagg atcgggcctt gatgttaccc gagagcttgg cacccagcct 6960 gcgcgagcag ctgtcgcgtg cacgggcatg gtggctgaag gaccaggccg agggccgcag 7020 cggcgttgcg cttcccgacg cccttgagcg gaagtatccg cgcgccgggc attcctggcc 7080 gtggttctgg gtttttgcgc agcacacgca ttcgaccgat ccacggagcg gtgtcgtgcg 7140 tcgccatcac atgtatgacc agacctttca gcgcgccttc aaacgtgccg tagaacaagc 7200 aggcatcacg aagcccgcca caccgcacac cctccgccac tcgttcgcga cggccttgct 7260 ccgcagcggt tacgacattc gaaccgtgca ggatctgctc ggccattccg acgtctctac 7320 gacgatgatt tacacgcatg tgctgaaagt tggcggtgcc ggagtgcgct caccgcttga 7380 tgcgctgccg cccctcacta gtgagaggta gggcagcgca agtcaatcct ggcggattca 7440 ctacccctgc gcgaaggcca tcggtgccgc atcgaacggc cggttgcgga aagtcctccc 7500 tgcgtccgct gatggccggc agcagcccgt cgttgcctga tggatccaac ccctccgctg 7560 ctatagtgca gtcggcttct gacgttcagt gcagccgtct tctgaaaacg acaggtcaag 7620 cgcgtatggg cgctgcacaa ccaggcgcag gcgtgaccta ctcggccggc tcggggtagt 7680 tcatccacag ccgttcgata gcgatgccgc cgcgcgtcat cgcgttgaag tcgatggttc 7740 tccatgacgc caagggagag ctgtcataga tcgttgagct gtagcccgac accatcaccg 7800 cgcacggcaa gccggccagc acgtcga 7827 // |
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