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EBI DbfetchID X66504; SV 1; linear; genomic DNA; STD; PRO; 13320 BP. XX AC X66504; S42592; XX DT 24-JUL-1992 (Rel. 32, Created) DT 23-OCT-2008 (Rel. 97, Last updated, Version 36) XX DE A.hydrophila exeC,D,E,F,G,H,I,J,K,L,M,N genes XX KW ExeC gene; ExeD gene; exeE gene; exeF gene; exeG gene; exeH gene; KW exeI gene; exeJ gene; exeK gene; exeL gene; exeM gene; exeN gene. XX OS Aeromonas hydrophila OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales; OC Aeromonadaceae; Aeromonas. XX RN [1] RP 2829-6936 RX DOI; 10.1111/j.1365-2958.1992.tb00856.x RX PUBMED; 1640836. RA Jiang B., Howard S.P.; RT "The Aeromonas hydrophila exeE gene, required both for protein secretion RT and normal outer membrane biogenesis, is a member of a general secretion RT pathway"; RL Mol. Microbiol. 6(10):1351-1361(1992). XX RN [2] RC revised by [3] RA Howard S.P.; RT ; RL Submitted (19-JUL-1992) to the EMBL/GenBank/DDBJ databases. RL Howard S.P., Faculty of Medicine, Memorial University of Newfoundland, St RL John's Newfoundland, Canada A1B 3V6 XX RN [4] RX PUBMED; 8407845. RA Howard S.P., Critch J., Bedi A.; RT "Isolation and analysis of eight exe genes and their involvement in RT extracellular protein secretion and outer membrane assembly in Aeromonas RT hydrophila"; RL J. Bacteriol. 175(20):6695-6703(1993). XX RN [5] RC revised by [6] MAT RA Howard S.P.; RT ; RL Submitted (09-DEC-1992) to the EMBL/GenBank/DDBJ databases. RL Howard S.P., Faculty of Medicine, Memorial University of Newfoundland, St RL John's Newfoundland, Canada A1B 3V6 XX RN [6] RP 1-13320 RA Howard S.P.; RT ; RL Submitted (29-SEP-1994) to the EMBL/GenBank/DDBJ databases. RL Howard S.P., Faculty of Medicine, Memorial University of Newfoundland, St RL John's Newfoundland, Canada A1B 3V6 XX DR GOA; P55901. DR InterPro; IPR003501; PTS_IIB_lac. DR InterPro; IPR013012; PTS_EIIB_3. DR InterPro; IPR014350; PTrfase_system_EIIB_3_subgr. DR UniProtKB/Swiss-Prot; P55901; PTEB_AERHY. XX FH Key Location/Qualifiers FH FT source 1..13320 FT /organism="Aeromonas hydrophila" FT /strain="Ah65" FT /mol_type="genomic DNA" FT /db_xref="taxon:644" FT CDS 1609..3645 FT /transl_table=11 FT /gene="ExeD" FT /db_xref="GOA:P31780" FT /db_xref="InterPro:IPR001775" FT /db_xref="InterPro:IPR004845" FT /db_xref="InterPro:IPR004846" FT /db_xref="InterPro:IPR005644" FT /db_xref="InterPro:IPR013356" FT /db_xref="UniProtKB/Swiss-Prot:P31780" FT /protein_id="CAA47124.1" FT /translation="MINKGKGWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVG FT KNLSKTIIIEPSVRGKINVRSYDLLNEEQYYQFFLSVLDVYGFAVVPMDNGVLKVVRSK FT DAKTSAIPVVDETNPGIGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYDPSN FT VLLITGRAAVVNRLVEVVRRVDKAGDQEVDIIKLKYASAGEMVRLVTNLNKDGNSQGGN FT TSLLLAPKVVADERTNSVVVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKD FT MVEVLKGVSSSIEADKKGGGTATTAGGGASIGGGKLAISADETTNALVITAQPDVMAEL FT EQVVAKLDIRRAQVLVEAIIVEIADGDGLNLGVQWANTNGGGTQFTNAGPGIGSVAIAA FT KDYKDNGTTTGLAKLAENFNGMAAGFYQGNWAMLVTALSTNTKSDILSTPSIVTMDNKE FT ASFNVGQEVPVQTGTQNSTSGDTTFSTIERKTVGTKLVVTPQINEGDSVLLTIEQEVSS FT VGKQATGTDGLGPTFDTRTVKNAVLVKSGETVVLGGLMDEQTKEEVSKVPLLGDIPVLG FT YLFRSTSNNTSKRNLMVFIRPTILRDANVYSGISSNKYTLFRAQQLDAVAQEGYATSPD FT RQVLPEYGQDVTMSPEAQKQIELMKTHQQATADGVQPFVQGNK" FT CDS 715..1587 FT /transl_table=11 FT /gene="ExeC" FT /db_xref="GOA:P45790" FT /db_xref="InterPro:IPR001639" FT /db_xref="UniProtKB/Swiss-Prot:P45790" FT /protein_id="CAA47125.1" FT /translation="MTLPFRNDLLSSLLARCKTVPLSRFSQPLFWLLLLLLAHQCAGLT FT WRLLDLGSQQASQPWQPAMVASQGQGSARLDLSGISRLSLFGKAKQQAQAADAVAADAP FT KTQLNAQLNGVLASSDPAKSIAIIAHNGVQNSYGIGDFIDGTQAKIRQVFADRVIIERD FT GRDETLMLDGEEYGKPLPKPGNQDDKLSSVRSELLGNPGKITDYLNISPVRVDGRMVGY FT RLNPGSNPELFNQLGLVANDMAVSINGLDLRDNAQAMQAMQQVAGATEMTVTVERQGQL FT YDVYVGLSE" FT CDS 3645..5150 FT /transl_table=11 FT /gene="ExeE" FT /db_xref="GOA:P31741" FT /db_xref="InterPro:IPR001482" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR013369" FT /db_xref="UniProtKB/Swiss-Prot:P31741" FT /protein_id="CAA47126.1" FT /translation="MAAYQLDDTSLPAALPELPFAFARNFGVVLTERQGTPLLLCRPGV FT APQTLLEVRRVAGCAFEVEQLGSDEFEELLMAHYQRDSSEARQLMEDLGNEMDFFALAE FT ELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLREIL FT RPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVL FT RLLDKNNVRLELKQLGMTLANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINS FT RDRNILTVEDPIEYDLEGVGQTQVNTKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQ FT IAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCR FT APRPITEQERLAMGMELAPDQQVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHS FT ASGELAIERLIRDHTPSIRRDGIDKVLKGQTSLEEVLRVTRED" FT misc_binding 4428..4451 FT /bound_moiety="ATP" FT /note="putative" FT CDS 5276..6442 FT /transl_table=11 FT /transl_except=(pos:5276..5278,aa:Met) FT /gene="ExeF" FT /db_xref="GOA:P31743" FT /db_xref="InterPro:IPR001992" FT /db_xref="InterPro:IPR003004" FT /db_xref="InterPro:IPR011850" FT /db_xref="InterPro:IPR018076" FT /db_xref="UniProtKB/Swiss-Prot:P31743" FT /protein_id="CAA47127.1" FT /translation="MTEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGA FT STSELALITRQLATLVGAGLTIEEALRAVAEQCEKAHLRSLVATVRSKVVEGYSLADSL FT GAFPHVFDQLFRSMVAAGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLTLVA FT VGVISILLTAVVPKVVAQFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFIGGFVWR FT WWLTDEKRRRHWHQVVLRLPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVL FT SNDFARTRIGEATERVREGTSLRKALDETKIFPPMMLHMIASGEQSGELDSMLERAADN FT QDREFETQVNIALGVFEPLLVVSMAGVVLFIVMSILQPILELNNMVNL" FT CDS 6552..6983 FT /transl_table=11 FT /gene="ExeG" FT /db_xref="GOA:P31733" FT /db_xref="InterPro:IPR000983" FT /db_xref="InterPro:IPR001120" FT /db_xref="InterPro:IPR010054" FT /db_xref="InterPro:IPR012902" FT /db_xref="InterPro:IPR013545" FT /db_xref="UniProtKB/Swiss-Prot:P31733" FT /protein_id="CAA47128.1" FT /translation="MQKRRQSGFTLLEVMVVIVILGILASLVVPNLMGNKEKADQQKAV FT SDIVALENALDMYKLDNNRYPTTEQGLDALVNKPTAAPEPRSYRDGGYIKRLPQDPWGN FT PYQMLSPGQFGKIDIFSMGLDGEAGTDDDIGNWNLKDFQ" FT misc_feature 6573..6593 FT /note="prepilin cleavage site" FT repeat_region 7045..7186 FT /rpt_type=DIRECT FT repeat_region 7152..7293 FT /rpt_type=DIRECT FT misc_feature 7253..7294 FT /note="prepilin cleavage site" FT CDS 7253..7804 FT /transl_table=11 FT /gene="ExeH" FT /db_xref="GOA:P31735" FT /db_xref="InterPro:IPR001120" FT /db_xref="InterPro:IPR002416" FT /db_xref="InterPro:IPR010053" FT /db_xref="InterPro:IPR012902" FT /db_xref="UniProtKB/Swiss-Prot:P31735" FT /protein_id="CAA47129.1" FT /translation="MRRHRQSGFTLLEVLLVAMLMGLVATAVTLSMGGARGDRELDKQA FT RRFMATLQQAQEYSVMDGRLVGLRIEDHGWQFMQRAAKDRKWQALTGDKILGQVQLPDT FT MLLAIELEGFSWRTESDEKTERGRDEKERTPQVLIFPGGELSPFVLTLTQQDEDVRYLR FT TVKADEFGRLRLLQDEEEEE" FT CDS 7801..8160 FT /transl_table=11 FT /gene="ExeI" FT /db_xref="GOA:P31737" FT /db_xref="InterPro:IPR001120" FT /db_xref="InterPro:IPR003413" FT /db_xref="InterPro:IPR010052" FT /db_xref="InterPro:IPR012902" FT /db_xref="UniProtKB/Swiss-Prot:P31737" FT /protein_id="CAA47130.1" FT /translation="MNARGMTLLEVMVALAVFAIAGLAVMKTASEHLSALNYLEEKTLA FT TWVVENQLVQQKLEAKWPGDSWVEGGEQMAGQTWYWRYRGVATADNNFKALDMEVRTAP FT KAESPVAFIRTYISR" FT misc_feature 7813..7833 FT /note="prepilin cleavage site" FT CDS 8181..8804 FT /transl_table=11 FT /gene="ExeJ" FT /db_xref="GOA:P31739" FT /db_xref="InterPro:IPR001120" FT /db_xref="InterPro:IPR010055" FT /db_xref="InterPro:IPR012902" FT /db_xref="UniProtKB/Swiss-Prot:P31739" FT /protein_id="CAA47131.1" FT /translation="MKSRQGGFTLLEMLVAIAIFASLSMGAYQVLQGVLTSDEVAKKKE FT ARLSELQLAFTLMERDITQMVPRSGRIDGENNKVLLAASRFGQQSDDWGMAFIRGGWLN FT PDGMLPRSGLQRVGWRLKDHKLERLSYLYPDPVIGTEPRIQPMLDRVTALRLYFYDKGA FT WKEEWTQRNVLPYGLAVELDLEDYGTLRRQFLIGAGGQRAENAN" FT misc_feature 8199..8219 FT /note="prepilin cleavage site" FT CDS 8818..9813 FT /transl_table=11 FT /gene="ExeK" FT /db_xref="GOA:P31760" FT /db_xref="InterPro:IPR005628" FT /db_xref="UniProtKB/Swiss-Prot:P31760" FT /protein_id="CAA47132.1" FT /translation="MPSCRRQGGMALLVVLLILSVMVIIASNMSGRLQLELRRTGNLTA FT GKQAWWYAMSAEALVSKVLVQDFKDDPNVVNLGQNWARQDAVFPVDDGKLTGRVRDLQS FT CFNLNSLSVPLKDGISGDDLEKQPYPVKAFRALLKQLEVEDYEAVQLTDAIRDWTDKDT FT ALVSSYGAEDAYYEGLTPPYLTANQWMLSTDELRAVRGVSARLYARLAPYVCALPSDKL FT LVNINTIKPEQAALLVALYLDKVGLDDAKRVLTSRPQKGWKEKKAMTDQMPAPLSTIPG FT LDAVLDVKSSYFEARLIAEVGDTRARLESVFVRGKDNKLVMLRRLNGGAE" FT CDS 9917..11086 FT /transl_table=11 FT /gene="ExeL" FT /db_xref="GOA:P45789" FT /db_xref="InterPro:IPR007812" FT /db_xref="UniProtKB/Swiss-Prot:P45789" FT /protein_id="CAA47133.1" FT /translation="MAGEIFVSESLVIRLGTNAQQPVEWLVWSAKEEEIIASGILASAH FT ALGELRERAGGRPVVTLVPGSDLIFRRVSLPGKYSRQAAAALPYLLEEQIASDVDELHL FT VVLGHEGHEVDLMAVDKEKMQIWLGWLQQAGLKSQQLLPDVLALPPAADGWSALQLGKE FT WLLRQGPCQGIVADESLLAMLLAAEADPVTIHSHTPLPAIPAANWLAADPELPMLLLAK FT GALNCQANLLQGPYRPQTEYSRYWLQWRKVAVVAGLLLLVALTQRGMHLYQLAEQDKAL FT KAEIRQVYTRIFPGENRIVNVRSQMAQHLKLLGQTPQDGVLLLLTELAPTFAEVPGLKP FT QVLRFDAARGELRLQVTAPGFAEIERFRELAGKRFEVQQGEGAQHRGQG" FT CDS 11117..11608 FT /transl_table=11 FT /gene="ExeM" FT /db_xref="GOA:P41850" FT /db_xref="InterPro:IPR007690" FT /db_xref="UniProtKB/Swiss-Prot:P41850" FT /protein_id="CAA47134.1" FT /translation="MMDKLQGWWRSISAREQRLVAVGGSCLLIGFCYWIVWQPIANRIA FT ERERQVLSQQQTLAWLKEKGEEVLAMQGGQGRQIDTSGTLEGVVNRTAFNQKIKIARLQ FT PQGQELQVWIDTVQFDDLLIWLASLADQHGVQVQVIEVARENLAPGLVKVRRLQLSRPQ FT " FT CDS 11706..12464 FT /transl_table=11 FT /gene="ExeN" FT /db_xref="GOA:P41852" FT /db_xref="InterPro:IPR000645" FT /db_xref="UniProtKB/Swiss-Prot:P41852" FT /protein_id="CAA47135.1" FT /translation="MKQKVLIAALFLVAYLGFLLVKLPATLVVRHLPLPPNLVQLEGVS FT GTLWSGQVARLQYASESLTQLRWELNGWSLLRFAPEVSLRFGDRSGLNGQGVVGWNGAA FT FGRDITLNVPAPWVLDRVPMRLPFPLTVAGQLQLKVDQFAQGNPWCDNLYGNLHWYGAD FT ADTPAGKLPLGDPELKLTCIDSRLVAELKQGSEAVQVLGKLELQPNRQYLFQGTLKPGP FT ELPDQMKQGLPFLGQPDGQGRFPLRYQGRI" FT repeat_region order(12478..12487,12491..12500) FT /rpt_type=INVERTED XX SQ Sequence 13320 BP; 2608 A; 3919 C; 4293 G; 2500 T; 0 other; agatcttggt tactcatcat gcattcctgg gttcttaggt gaggtaaata gataaaaaca 60 ttattaaaca ggtggttagg aactaatccc gtttcctgtc gtcataaaag ggccacgttg 120 gcgagtcagt attgcttgac cttgatcagc tggcgccgct cctgcttgtc gggacgacgc 180 tcggggctcg gggcaaactg gctgttgaag cgacgcgcct cgctgttctc ggcccgtttt 240 ttcaggctgg cttccgtctc ttcatagagc agctgggcca gcggggcgga cttgcgctgt 300 tcgctcactt gcagcacccg cacctcccgt tcgtcctggc cttgccagac acggatgagg 360 gcaccggctt cgacggcctt gcccggcttg ctgcgctggc cgttgtagtg caccttgccc 420 ccttcaatct gctcgcgggc caggctgcgg gtcttgtaaa aacgcgccgc ccacaaccat 480 ttgtcgaggc ggacctgggt tgtggtttct gcgggattcg gcatgaatcg actccgggat 540 ggctgaaagg ggagcctgat tataccagag gcaggcctcg ggatagaaac gggggggctt 600 atggtgtgac ggaatgtcaa ttttcgcagc ttcatcccat ccggtcggtt gtctctgggt 660 ccattgccgt acacaatagc caaccgattt ggatgccaga atatattgat aaacatgacg 720 ctaccgttca ggaatgactt gttgagctcc cttctggccc gttgcaaaac cgtgccgctc 780 tcccgtttca gccagcccct gttctggctt ctgctgctgt tgctggccca ccagtgcgcc 840 ggtctcacct ggcgtctgct ggatctcggc agccagcagg ccagccaacc ctggcagccg 900 gccatggtcg ccagtcaggg ccaaggttcg gcccggctcg atctcagcgg catcagccgg 960 ctgtcgctgt tcggcaaggc gaagcaacag gcccaggcgg ccgatgctgt cgcagccgat 1020 gcccccaaga ctcagctcaa cgcccagctc aacggtgtgc tggcgagttc agatccggcc 1080 aaatccatcg ccatcatcgc ccacaacggc gtgcagaact cctatggcat aggtgatttc 1140 atcgatggca cccaggccaa gatccgtcag gtgttcgccg atcgcgtcat catagagcgg 1200 gacgggcggg acgagaccct gatgctggac ggggaagagt acggcaagcc gttgcccaaa 1260 ccgggcaatc aggatgacaa gctctcctcg gtgcgcagcg aactgctggg caaccccggc 1320 aagatcaccg attacctcaa tatttccccg gtgcgggtag atggccgcat ggtcggctat 1380 cgcctcaatc cgggcagcaa tccagagctg ttcaatcaac tcggtctggt cgccaacgac 1440 atggcggtca gcatcaatgg cctggatttg cgagataacg ctcaggccat gcaggcaatg 1500 cagcaggtgg ctggcgccac ggaaatgacc gtcaccgtcg agcggcaagg acagctctac 1560 gacgtttatg tcggcttgtc agaataatga tttggagtag caccaagaat gataaataaa 1620 gggaagggct ggcgtctggc cacggttgcg gcggcgctga tgatggcggg ctccgcctgg 1680 gccaccgagt attctgccag cttcaagaat gccgacatcg aagagttcat caacacggtc 1740 ggcaagaacc tgagcaagac catcatcata gagccttcgg tgcgcggcaa gatcaacgtc 1800 cgcagttacg acctgctcaa cgaggagcag tactaccagt tcttcctgag cgtgctcgac 1860 gtctatggct tcgccgtggt gcccatggat aacggtgtgc tcaaggtggt gcgctccaag 1920 gacgccaaga cctcggccat cccggtggtg gatgagacca acccgggcat aggcgacgag 1980 atggtgaccc gggtggtgcc tgtgcgcaac gtctcggtgc gcgaactggc gcctctgctg 2040 cgccagctca atgacaacgc cggtggcggc aacgtggtcc attacgatcc ctccaacgtg 2100 ctgctcatca cgggccgtgc cgctgtggtc aaccgtctgg tggaagtggt tcgccgggtc 2160 gacaaggcag gggatcagga agtggacatc atcaagctga aatatgcctc cgccggcgag 2220 atggtgcggc tggtgaccaa cctcaacaag gatggcaaca gtcagggcgg caacacctcc 2280 ctgctgctgg ctcccaaggt ggtggccgac gagcgtacca actctgtggt ggtcagtggc 2340 gaacccaagg cgcgggcccg catcatacag atggtgcgcc agctcgatcg ggatctgcag 2400 agccagggca acacccgggt cttctacctg aaatacggca aggccaagga tatggtggag 2460 gtgctcaagg gcgtcagctc cagcatagaa gcggacaaga agggcggcgg cacagctacg 2520 acagcgggtg gcggcgccag catagggggt ggcaagctgg ccatctccgc cgacgagacc 2580 accaatgcct tggtcatcac ggcccagccg gatgtgatgg ccgagctgga gcaggtggtc 2640 gccaagctgg atatccgccg cgcccaggta ctggttgagg cgatcatagt cgagatcgcc 2700 gacggcgacg gcctcaacct cggggtgcag tgggccaata ccaacggcgg cggcacccag 2760 tttaccaatg ccggtccagg tataggttct gtggccattg ccgccaagga ttacaaggat 2820 aacggtacca ctacgggtct tgccaagctg gctgagaatt ttaacggcat ggcggccggt 2880 ttctatcaag gtaactgggc catgttggtg acggcactgt cgaccaacac caagagcgat 2940 attctctcca ccccgagtat cgtcaccatg gataacaagg aagcctcctt caacgtcggt 3000 caggaagtgc cggtgcagac gggcacccag aactccacct ccggtgacac cacctttagc 3060 accatagagc gcaagactgt gggcaccaag ctggtggtga cgccgcagat caacgaaggg 3120 gactcggtgc tgctgaccat agagcaggag gtctccagcg tgggcaaaca agcgacaggt 3180 acggacggtc tgggccccac cttcgatacc cgtacagtca agaacgccgt gctggtgaaa 3240 agcggtgaga ctgtggtgct gggtggcctg atggatgagc agaccaagga agaggtttcc 3300 aaggtgccgc tgctcgggga tatccctgta ctcggctatc tgttccgttc cacttccaat 3360 aacacttcca agcgcaacct gatggtcttt atccggccca ccatattgcg ggatgcaaac 3420 gtctactcag gcatttccag caacaagtac accctgttcc gtgctcaaca gctagatgct 3480 gttgctcaag aaggatatgc cacctcaccg gatcgtcagg tgctgcctga atatggccag 3540 gatgtgacca tgtctcccga ggcgcagaag cagatcgagc tgatgaaaac acaccagcag 3600 gcgacggccg acggagtgca accattcgtt cagggtaaca agtaatggct gcgtaccagc 3660 ttgatgacac gagtctgcct gcagccctgc ctgagctgcc gttcgccttt gcccgcaact 3720 tcggtgtcgt tctgaccgag cggcagggga cccccctgct gctgtgccgt cctggggtgg 3780 cgccgcaaac cctgctggag gtacggcgag tggcgggctg cgccttcgag gtggagcagc 3840 tcggcagtga cgagtttgaa gagctgctga tggcgcacta ccagcgcgac tcctccgagg 3900 cgcgccagct gatggaagat ctcggcaacg agatggactt cttcgccctg gcggaagagc 3960 tgccgcaaag cgaggatctg ctggacgccg atgacgacgc ccccatcatt cgcctcatca 4020 atgccatgtt gagcgaggcg ataaaagagg aggcgtctga catccatatc gagaccttcg 4080 agcgggtgct ggtcattcgt ttccgcatcg atggcgtgct gcgggagata ctgcgccccc 4140 atcgcaagct ggcctccctg ctggtgtcgc gcatcaaggt catgtcgcgg atggacatag 4200 ccgagaagcg ggtgccccag gatggccgca tctcgctgcg tatcggtggc cgggcggtgg 4260 acgtgcgggt ctccaccatg ccgtccagct acggcgagcg ggtggtattg cgtctgctcg 4320 acaagaacaa cgtgcgcctc gagctcaagc agctcggcat gacgctggcc aaccgcaaca 4380 tcatcagcga actcattcgc aagccccacg gcatcatatt ggtgacgggc ccgaccggtt 4440 cgggcaagtc caccaccctg tatgcggcgc tctccgagat caactcgcgg gatcgcaaca 4500 ttctcacggt ggaagaccct atcgaatatg acctggaggg tgtgggtcag actcaggtca 4560 acaccaaggt ggacatgacc ttcgcccgcg gcctgcgcgc cattctgcgt caggatccgg 4620 atgtggtgat ggtgggggaa attcgcgacc tcgagaccgc ccagatagcg gtgcaggcgt 4680 cgctgaccgg tcacctggtg atgtcgaccc tgcacaccaa caccgccata ggtgccatca 4740 cccggatgcg ggacatgggg atagagcctt tcctgctctc ctcgtccctg ttggcggttc 4800 tggcccagcg gctggtgcgg accctctgcc cggattgccg cgccccgcgc cccatcacgg 4860 agcaggagcg tctggccatg ggcatggaac tggcgccgga tcagcaggtg tggcggccgg 4920 tgggctgcga gcagtgcaac cacaccggct atcgcggccg gaccggcatt cacgagctgg 4980 tggtgatcga cgaggcggtg cgcgaagcga tccacagcgc cagcggcgag ctggccatcg 5040 agcggctgat ccgggaccat acccccagca tacgccgcga cggcatcgac aaggtgctca 5100 aggggcagac cagcctcgaa gaggtgctgc gcgtgacccg ggaagattga tgtttggtca 5160 ggcaagcgat ttgaatcggg ataacgagac gtcacagtgc tagggcagag gagcaagagt 5220 attgtcagca tttgaataca aagccctcga cagcaagggg cgccagaagc agggggtgac 5280 cgagggtgac tcggcccgtc aggtgcgcca gcaactgcgt gagcaggggc tgaccccgct 5340 cgaggtgaac gagaccacag agaaggcaaa gcgggaagcg aatcgcttcg tgctgtttcg 5400 ccgtggcgcc tccacctcag agctggccct catcacccgt cagctggcga ccctggtggg 5460 cgcagggctg accatcgaag aggcgctgcg ggcggtggcc gagcagtgcg agaaggccca 5520 tctgcgcagc ctggtggcga cggtacgcag caaggtggta gaaggttact cgctggccga 5580 ttcgctgggg gccttccctc acgtgttcga tcagctgttt cgctccatgg tggcggccgg 5640 tgaaaaatcg ggccatctgg agaaggtgct gaaccggctc gccgactaca cggagcagcg 5700 ccagcacatg cgcaccaagc tgctgcaggc gatgatctac cccatagtcc tcactctggt 5760 ggcggtcggg gtcatctcga tcctgctcac tgcagtcgtg cccaaggtag ttgcccagtt 5820 tgaacacatg ggccagcaac tgcctgcgac gacccgtttc ctcatcggca ccagcgagct 5880 gatgcagcat tacggcctct ggttcctgct gctgctgttt atcggtggtt ttgtctggcg 5940 ctggtggctg accgacgaga agcgtcgccg tcactggcat caggtggtgc tgcgcctgcc 6000 ggtcataggc cgggtcagcc gtggtctcaa cacggcccgc ttcgcccgca ccctcagcat 6060 actcaacgcc agcgccgtcc ccctgctgga ggggatgaag attgccggcg aggtgctctc 6120 caatgacttc gcccgtactc gcatcggtga ggccaccgaa cgggtgcggg aggggaccag 6180 cctgcgcaag gcactggatg aaaccaagat tttcccgccc atgatgctgc acatgatcgc 6240 ctccggcgag cagagcggcg agctcgacag catgctggag cgggcggctg acaaccagga 6300 cagggaattt gaaacccagg tgaatatcgc cctcggcgtg ttcgagcccc tgctggtggt 6360 ctccatggcc ggggtcgtgc tgtttatcgt gatgtcgatc ctgcagccga tcctcgagct 6420 caacaacatg gtgaatttat gatgttggcg tgagggtgac ttcggtcgat cctgccgtca 6480 attcgctcga actcaataat atggtcaatc tctgatggcc cgcgccatct catttcgtta 6540 gggagtaagt catgcaaaag cgtcgtcaat ccggttttac cctgctggaa gtcatggtgg 6600 tcatagtgat cctcgggatc ctggccagcc tggtggtgcc caacctgatg ggcaacaagg 6660 agaaggctga ccagcagaaa gccgtctccg acatagtggc gctggaaaat gccctcgaca 6720 tgtacaagct ggacaacaac cgttacccga ccacggagca aggcctggat gcgctggtca 6780 acaagccgac cgccgccccc gagccgcgca gctaccgtga cggcggctac atcaagcgcc 6840 tgccgcagga tccctggggc aacccgtacc agatgctgag cccgggccag tttggcaaga 6900 tcgacatctt ctccatgggg ctggatggcg aagccggtac cgatgacgac atcggcaact 6960 ggaatctgaa ggatttccaa taagtgattg attgcgctgc catcaagctg ctgtggatga 7020 ggctgccgtg agggcttgtc gtctcgccat cgccaagccg atttccccct gctggaggtg 7080 atgttgagtg gcgccatgct gatgaggcgg gagtctgctg tcgtcgcctt ggtggggtgg 7140 gaccaatgag gcgtcatcgc cagtcgggtt tcaccctgct ggaggtgatg ttgagtggcg 7200 ccatgctgat gaggctgaag tctgctgtcg tcaccttggt ggggtgggac caatgaggcg 7260 tcatcgccag tcgggtttca ccctgctgga ggtattgctg gtggccatgc tgatggggct 7320 ggtggccacc gccgtcaccc tcagcatggg aggcgccaga ggcgatcgcg aactcgacaa 7380 gcaggcgcgt cgtttcatgg cgaccctgca acaggcgcag gagtattcgg tgatggatgg 7440 ccggctggtg gggcttcgca tcgaggatca cggctggcag ttcatgcagc gtgccgccaa 7500 ggatcgcaag tggcaggcgc tgaccggcga caagatcctg ggacaggtac aactgcccga 7560 caccatgctg ctggccatcg aactcgaagg gttcagctgg cgaaccgagt ccgacgagaa 7620 aaccgagcgg ggtcgggacg agaaggagcg cacgccccag gtgctgatct tccccggtgg 7680 cgagctcagc cccttcgtgc tgaccctgac ccagcaggat gaggatgtgc gctacctgcg 7740 tacggtcaag gcggatgaat tcggccgctt gcgactgctg caggacgagg aggaagagga 7800 atgaacgccc gtggcatgac attgctggaa gtcatggtcg cactggcggt gtttgccatc 7860 gcgggtctcg ccgtgatgaa aaccgccagc gagcacctct ctgcgctcaa ttatctggaa 7920 gagaagacgc tggcgacctg ggtggtggag aatcagctgg tacagcagaa gctggaggcc 7980 aagtggcccg gtgacagctg ggtggaaggg ggcgagcaga tggcgggcca gacctggtac 8040 tggcgctatc gcggcgtcgc caccgccgac aacaacttca aggcgctgga tatggaagtg 8100 cgtaccgcgc ccaaggccga gagcccagtg gccttcatcc ggacctatat cagccgatga 8160 caacagccaa cgacacccaa atgaagtccc gtcagggcgg cttcaccctg ctggagatgc 8220 tggtggccat cgccatcttc gccagcctca gcatgggcgc ctatcaggtg ctgcaagggg 8280 tgctcaccag cgacgaggtg gccaagaaga aggaggcccg cctctccgaa ttgcagctgg 8340 ccttcaccct gatggagcgg gacatcaccc agatggtgcc ccgcagcggc cgtatcgacg 8400 gcgagaacaa caaggtgctg ctggcggcat cccgcttcgg ccagcagagc gatgactggg 8460 gcatggcctt cattcgcggc ggctggctca acccagatgg catgctgcca cgttccggtt 8520 tgcagcgggt cggctggcgg ctcaaggatc acaagctgga gcggctgagc tatctctacc 8580 cggatcccgt gataggcact gagccgcgca tccagcccat gctggatcgg gtgacggcgc 8640 tgcggctcta tttttacgac aagggggcct ggaaggagga gtggacccag cgcaacgtgc 8700 tgccttacgg cctggctgtg gagctggatc tggaagatta cggcaccctt cgccgccagt 8760 tcctcatcgg ggccggtggc cagcgagctg aaaatgcgaa ctaagcggac cggcagcatg 8820 ccgtcttgtc gtcgccaggg gggcatggcc ctgctggtgg tgctgctcat cttgtcggtg 8880 atggtgatca tcgccagcaa catgagtggc cgcctgcagc tggagttgcg ccgtaccggc 8940 aacctcaccg ccggcaagca ggcctggtgg tatgccatgt cggcggaagc cctggtgagc 9000 aaggtgctgg ttcaggattt caaggatgac cccaatgtgg tgaacctggg gcagaactgg 9060 gccaggcagg atgctgtctt cccggtggat gacggcaagc tgaccggccg ggtgcgggat 9120 ctgcaatcct gcttcaacct caacagcctg agcgtgcccc tgaaagacgg gatcagcggc 9180 gacgacctcg agaagcagcc ttatccggtc aaggcgtttc gcgccctgct caagcagctt 9240 gaggtcgagg attacgaggc ggtgcagctg accgatgcca tccgcgactg gaccgacaag 9300 gacacggcac tggtctccag ctacggcgcc gaggatgcct attacgaggg gctgacgccc 9360 ccttatctga ccgcgaacca gtggatgctc agcacggacg agctgagggc ggtgcgcggt 9420 gtgagcgcca ggctgtatgc ccggctggcg ccttatgtct gcgccctgcc gagcgacaag 9480 ctgctggtga acatcaacac catcaagccg gaacaggcgg cgctgctggt ggccctctat 9540 ctggacaagg tggggctcga tgacgccaag cgggtgctga ccagccgtcc ccagaagggg 9600 tggaaggaga aaaaggcgat gacggatcag atgccggcgc cgctgagcac catccccggg 9660 ctggatgccg tgctggacgt caagagcagc tacttcgagg ccaggctgat cgccgaagtc 9720 ggtgataccc gggctaggct ggagagcgtc ttcgtgcgtg gcaaggacaa caagctggtg 9780 atgctgcgtc gcctcaacgg cggcgccgaa tgacagacag gtgtgggtgg cggccgctgg 9840 ccgtacccgc cctgaccccg tattggacag cagccaaggg ctgcgctccc gcccatccag 9900 agggatgcgg acgggaatgg caggagagat atttgtgagc gagagtctgg tcatccgtct 9960 ggggaccaat gcgcagcaac cggtcgagtg gctggtgtgg tcggccaagg aggaggagat 10020 cattgcctcc ggcatcctgg cctcggccca tgccctcggc gagttgcggg agcgtgccgg 10080 tggccgcccc gtggtgaccc tggtaccggg cagcgatctt atcttccggc gggtgagcct 10140 gccgggcaaa tacagtcgcc aggccgcggc cgccttgccc tacctgctgg aggagcagat 10200 cgcatccgac gtggatgagc tgcatctggt ggtgctgggc cacgagggcc acgaggtgga 10260 cctgatggcg gtcgacaagg agaagatgca gatctggctg ggctggctgc agcaggcggg 10320 cctcaagagc cagcagctgt tgccggacgt gctggccctg ccgccggctg ccgacggctg 10380 gtctgccctg caacttggca aggagtggct gctgcgtcag ggcccctgtc agggcatagt 10440 ggccgacgag tcgctgctgg ccatgttgct ggcggccgag gccgaccccg tcaccatcca 10500 cagccatacc cccttgccgg cgatcccggc ggccaactgg ctggcggcgg atcccgaact 10560 gcccatgctg ttgctggcca aaggggcgct gaactgccag gccaacctgt tgcagggccc 10620 ctaccggccg cagaccgaat actcccgcta ctggctgcag tggcgcaagg tggccgtggt 10680 ggccgggctc ttgctgctgg tggcgctgac ccagcgcggt atgcatcttt atcagctggc 10740 ggagcaggac aaggccctca aggccgagat ccggcaggtc tacacccgca tcttcccggg 10800 ggagaaccgc atcgtcaacg tacgcagcca gatggcacag cacctcaagt tgctggggca 10860 gaccccgcag gatggcgtgc tcttgctgct gaccgaactg gccccgacct ttgccgaggt 10920 gccgggcctc aagccgcagg tgttgcgttt cgacgccgct cggggcgagc tgagattgca 10980 ggtgacggcg cccggtttcg ccgagataga acgctttcgc gaactggcgg gcaagcgctt 11040 cgaggtgcag cagggcgagg gtgcgcagca cagagggcaa ggttgaaggg gcactggtgc 11100 tgaagggtaa atcatcatga tggacaaact acaaggctgg tggcgcagca tcagcgcccg 11160 cgagcagcgg ctggtggccg tggggggcag ctgcctgctg atcgggttct gctactggat 11220 cgtctggcaa cccatcgcca accgcatcgc cgagcgcgag cggcaggtgc tgagccagca 11280 acagacgctc gcctggctga aagagaaggg ggaagaggtg ctggcgatgc agggcggtca 11340 gggccgtcag atcgacacca gcggtaccct ggaaggggtg gtgaaccgca ccgccttcaa 11400 ccagaagatc aagattgccc gtctgcaacc ccagggtcag gagctgcagg tgtggatcga 11460 tacggtccag ttcgatgatc tgctgatctg gctggcgagc ctggccgatc agcacggcgt 11520 ccaggtgcag gtgatcgagg tggcccgcga gaatctggca ccgggtctgg tcaaggtcag 11580 gcgcctgcag ttgagccgtc cccaatgacg ccaggcgtgc cgggcgtcgt ccggtttcct 11640 gcatctcgtc ccggtatggt gccgggcctg gccaaggcca gatatttgca atcgagtcgt 11700 tttctatgaa gcaaaaagta ctgatcgccg ccctgttcct ggtggcctat ctcggttttc 11760 tgctggtgaa actgccagcc accctggtgg tgcgccatct gccgctgccg cccaacctgg 11820 tgcagctgga aggggtgagc ggcaccctct ggagcggcca ggttgcccgg ctgcaatacg 11880 ccagcgagtc gctgacccag ctgcgctggg agctcaacgg ctggtcgctg ctgcgcttcg 11940 cccccgaggt ctccctgcgt ttcggtgatc gcagcggcct caacggccag ggcgtggtcg 12000 gctggaacgg cgccgccttt ggtcgcgaca tcaccctcaa cgtgcccgcg ccctgggtgc 12060 tggatcgggt gcccatgcgg ctgccgttcc cgctgacggt ggcgggccag ctgcagctca 12120 aggtcgatca gtttgcccag ggcaatccct ggtgtgacaa cctctacggc aacctccatt 12180 ggtatggtgc cgatgccgat accccggccg gcaagctgcc gctgggggat cccgagctca 12240 agctgacctg catcgactcc cggctggtgg ccgagctcaa gcagggctcg gaggcggtgc 12300 aggtgctggg caagctggag ctgcagccca atcgccagta cctgttccag ggcaccctca 12360 aaccgggccc ggaactgccg gatcagatga agcaggggct gcccttcctc ggtcagcccg 12420 acggtcaggg gcgcttcccg ctgcgctatc agggccggat ttaaatccct ccccgccgac 12480 cccggagcct ctccggggtc tactttttcc ctctgctctg ccccctcata gtcctcgctc 12540 actgactgcc acttcccttg cgagtgcgcc tgcttgccct ctttgccagc ccggcaacgg 12600 cttgcctcac tggtatgttc atccgtagcc aatggtcaat gaacgcgcac cactccgcaa 12660 aaatggcaac tcatctcccg aaaaaccgaa tatcaatcag gttgcatttt atgtgaagtg 12720 tgagctgaca cccgttattg atcttttcca tcctgattac agcgttgcca cagaaataaa 12780 aaataactat atgaaaaata acgattaaat gtgtatggca attgtcttta agcccctttt 12840 tagctcattg ctcctggtcc accccatcaa agatgtgagc ggcggcaaaa tgcgtggtca 12900 ataagagaca attggtatga gcatcgaaat accagatgaa acctatgggt agttacaatg 12960 atgtcaattg gagatgattg atttgtcttg atagcgcgac aggtaaccat ctcgaccggt 13020 ctgttcattt ggttttcaag cgttgaggta agggttatgg aaaagaagcg tatctacctg 13080 ttttgctctg ctggtatgtc cacgtcactg ctggtctcga agatgaaggc tcaggcggaa 13140 aaatatgatg tgcctgtgtt gatcgatgcc tatccggaaa cgctggcagg cgagaaggga 13200 caagatgccg acctggtgct gctggggccg caaatcgcct acatgctgcc ggagatccag 13260 cagcagctgc cgggcaagcc ggtcgaagtg attgacaccc tgctctacgg caaggtcgac 13320 // |
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