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EBI DbfetchID X64275; SV 1; linear; genomic RNA; STD; VRL; 15450 BP. XX AC X64275; S46730; XX DT 01-DEC-1993 (Rel. 38, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 9) XX DE Simian parainfluenza virus 41 NP, P-V, M, F, HN and L genes, genomic RNA XX KW F gene; fusion protein; haemagglutinin-neuraminidase; HN gene; L gene; KW Large protein; M gene; matrix protein; NP gene; KW nucleocapsid phosphoprotein; nucleocapsid protein; P gene; V gene. XX OS Simian virus 41 OC Viruses; ssRNA negative-strand viruses; Mononegavirales; Paramyxoviridae; OC Paramyxovirinae; Rubulavirus. XX RN [1] RP 1-15450 RA Kawano M.; RT ; RL Submitted (22-JAN-1992) to the EMBL/GenBank/DDBJ databases. RL Kawano M., Deptartment of Microbiology, Mie University School of Medicine, RL 2-174 Edobashi, Tsu-shi, Mie Prefecture 514, JAPAN XX RN [2] RX PUBMED; 1328485. RA Ogawa M., Mutsuga N., Tsurudome M., Kawano M., Matsumura H., Kusagawa S., RA Komada H., Nishio M., Ito Y.; RT "Nucleotide sequence analysis of the simian virus 41 gene encoding the RT large (L) protein and construction of a phylogenetic tree for the L RT proteins of paramyxoviruses."; RL J. Gen. Virol. 73:2743-2750(1992). XX RN [3] RA Kawano M., Tsurudome M., Oki N., Nishio M., Komado H., Matsumura H., RA Kusagawa S., Ohta H., Ito Y.; RT "Sequence determination of the P gene of simian virus 41: presence of RT irregular deletions near the RNA-editing site of paramyxoviruses."; RL J. Gen. Virol. 74:911-916(1993). XX FH Key Location/Qualifiers FH FT source 1..15450 FT /organism="Simian virus 41" FT /isolate="Toshiba/Chanock" FT /mol_type="genomic RNA" FT /db_xref="taxon:11228" FT CDS 158..1789 FT /gene="NP" FT /product="nucleocapsid" FT /db_xref="GOA:P27018" FT /db_xref="InterPro:IPR002021" FT /db_xref="UniProtKB/Swiss-Prot:P27018" FT /protein_id="CAA45570.1" FT /translation="MSSVLKTFERFTIQQELQDHEEDTPVPLETIRPLIRVFVVNSNDP FT ALRAQLLLFNLRIIMSNTARESHKTGALLSMFSLPAAAMGNHLKLATRSPEASIDRVEI FT TGFEGRSFRVVPDARSTMSRAEVLAYEAIAEDIPDTLNHKTPFVNADVEQGDYDETEGF FT LELCYSVLMQAWIVTCKCMTAPDQPPISIEKRMAKYQQQGRINPRFILQPEARRIIQNA FT IRKAMVVRHFLTYELQMAQSKTLLANRYYAMVGDVGKYIEHSGMGGFFCTLKYGLGTRW FT PTLALAAFSGELQKLKALMLHYQSLGPMAKYMALLESPKLMDFAPAEYPLMYSYAMGIG FT TVIDTNMRNYAYGRSYLNPQYFQLGVETARKQQGAVDHRTAEDLGMSQADKVELAATLA FT KLTIGQGGRGRQPLDDPFAGAAGDYQGAAAGGAQGFDYASRRVRKYNDYESDEEAGMDD FT DYEQEAREGRGYDDDDARQGIGGQSGFDFSVPQRAPGMSDEEFQAQMTKYIQHVQQHYQ FT EAQEGAEDGGYNQTTDDQGAGGDFDT" FT mRNA 56..1899 FT CDS 1973..2650 FT /gene="P-V gene" FT /product="V protein" FT /db_xref="GOA:P36315" FT /db_xref="InterPro:IPR004897" FT /db_xref="UniProtKB/Swiss-Prot:P36315" FT /protein_id="CAA45571.1" FT /translation="MAEEPTYTAEQVNDVVHAGLGTVDFFLSRPVDGQSSLGKGSVPPG FT ITAVLTNAAELKAKTAAAAPVKPKRKKIQHMTPAYTIADNGDPNRLPANTPIANPLIPI FT ERPPGRMTDLDLATGTVTQGTYKGVELAKAGKNALLTRFSSGPSLTDQASSKDPNFKRG FT GEIDGRHKGRHRREWSIAWVGDEVKVYEWCNPTCAPVTATDRKFSCTCGTCPDRCGECE FT GDN" FT CDS 1973..3158 FT /exception="RNA editing" FT /gene="P-V gene" FT /product="P protein" FT /function="complexes with Large protein to form FT RNA-dependant RNA polmerase" FT /note="phosphoprotein" FT /db_xref="GOA:Q5KU50" FT /db_xref="InterPro:IPR004897" FT /db_xref="UniProtKB/TrEMBL:Q5KU50" FT /protein_id="CAA45572.2" FT /translation="MAEEPTYTAEQVNDVVHAGLGTVDFFLSRPVDGQSSLGKGSVPPG FT ITAVLTNAAELKAKTAAAAPVKPKRKKIQHMTPAYTIADNGDPNRLPANTPIANPLIPI FT ERPPGRMTDLDLATGTVTQGTYKGVELAKAGKNALLTRFSSGPSLTDQASSKDPNFKRG FT GEKLTDATKADIGGSGASPGSETKLRFMSGAIQHVPQLLPLTASSPVLVEPAPIGAENV FT KEIIEILRGLDLRMQSLEGKVDKILATSATITALKNEVTSLKANVATVEGMMTTMKIMD FT PSTPTNVPVEKIRKNLKDTPVIISGPLSESHITEGSDMIVLDELARPSLSSTKKIVRRP FT EPKKDLTGMKLMLIQLANDCMGKPDQKAEIVAKIHAATREAQLLDIKRSIIKSAI" FT variation 2457..2463 FT /replace="ccccccccc" FT /note="RNA editing, 7 Cs are replaced with 9 Cs in the P-V FT mRNA, the shorter mRNA translates to give the V protein, FT the longer mRNA translates to give the P protein" FT mRNA 1903..3308 FT /gene="P-V" FT /note="RNA editing" FT CDS 3393..4541 FT /gene="M gene" FT /product="matrix protein" FT /db_xref="GOA:P25182" FT /db_xref="InterPro:IPR000982" FT /db_xref="UniProtKB/Swiss-Prot:P25182" FT /protein_id="CAA45566.1" FT /translation="MPTISIPADPASPDQGLKPFPIQLDSKDGKSGKLVKQIRIKYLTE FT PNSRSPPLTFINTYGFIYARDLSGGIMNEQSSGIQSGSVTACMMTLGPGPDIKNANRVL FT AALNGFYVKVRKTSSLKEEAVFELVNVPKLLANHALCKQGRLVCSAEKFVKNPSKMMAG FT QEYLYFPTFVSLTYCPSNLNYQVAKPILKIRSRFVYSIHMEIIFRLLCKPDSPLLKTYA FT TDPEGRGCLASVWIHVCNILKNKKIKQRGVDSYFSSKAISMQLTVSIADTWGPTVIIKA FT NGHIPKTAAPFFSKDGVACHPLQDVSPALTKSLWSVGCEITKARLILQESNISDLLKTQ FT DLITDQIKIKKGHSHFGRSSFNPFKKAISLPNLTQLGQDDED" FT mRNA 3331..6536 FT /note="M/F mRNA" FT CDS 4760..6445 FT /gene="F gene" FT /product="fusion protein" FT /function="membrane fusion" FT /db_xref="GOA:P25181" FT /db_xref="InterPro:IPR000776" FT /db_xref="UniProtKB/Swiss-Prot:P25181" FT /protein_id="CAA45567.1" FT /translation="MRLTPYPIALTTLMIALTTLPETGLGIARDALSQVGVIQSKARSL FT MYYSDGSSSFIVVKLLPTLPTPSGNCNLTSITAYNTTLFKLLTPLMENLDTIVSANQAG FT SRRKRFAGVVVGLAALGVATAAQVTAAVAVVKANANAAAINKLAASIQSTNAAISDVIS FT STRTLATAIQAVQDHVNGVLASGLTEANCRSQDALIGSILNLYLTELTTIFHNQIVNPA FT LTPLSIQALRIILGSTLPLIVESRWNTNLNTAELLSSGLLTGQIISISPSYMQMVIQIT FT VPTFVMQPGAKIIDLVTITANRMEEEVLIQVPPRILEYANEIQAYTADDCVVTPHAVFC FT KYNDGSPISDSLYQCLKGNLTSCVFTPVVGNYLKRFAFANGVMYVNCKALLCRCADPPM FT VITQDDLAGITVIDITVCREVMLDTLAFKITSLNNVTYGANFSMLAAAIKDLSPLDLSA FT QLAQVNKSLASAEEKIAQSSSLAAQAVSQEATITVGSVAMLIAVLALIAGCTGIMIAVQ FT MSRRLEVLRHLTDQSIISNHHYAELNPPPYNHSYESLHPIPQSH" FT mRNA 4663..6536 FT CDS 6701..8407 FT /gene="HN gene" FT /product="heamagglutinin-neuraminidase" FT /db_xref="GOA:P25180" FT /db_xref="InterPro:IPR000665" FT /db_xref="InterPro:IPR011040" FT /db_xref="InterPro:IPR016285" FT /db_xref="UniProtKB/Swiss-Prot:P25180" FT /protein_id="CAA45568.1" FT /translation="MSGAEGNTNKRTFRAVFRTLIILITLTILALSAAILYEVTHTSNG FT SESNNQVFDPTDTLNAITGNIKSMIALLNQILYNAAIALPLKIDSTESVLLAAIKDLQF FT SNPASQNCSSGGNLLNDALYINGINQYLLSNSFAGTVGLGPLLNIPSFIPSATAPGGCT FT RIPSFSLTKTHWCYSHNVILAGCADSKASNQYLAMGIVEQSSADFPFFRTMRTLYLSDG FT INRKSCSIVAIPGGCALYCYVATKTEQEDYAATTPSELRLTFYYYNETLVERTLTIPNV FT TGNWATLNPAVGSGVYHLGYLAFPVYGGLIQNSAAWNSQFGSYFLPQNPAVQCSGSAEQ FT QINTAKGSYVVNWFSGRLIQSAVLVCPLSDQLTDQCRVVLFNNSETMMGAEGRLYTIGG FT DLYYYQRSSSWWTASLLYKINTDFSQGLPPLIEAQWVPTYLVPRPGAQPCSAGNFCPAN FT CITGVYADVWPMNNPFPAGSSGVNPNYLFGGAFLWADVARVNPTFYMASATQYKNTTGF FT PNSNQKAAYTSTTCFQNTGSKKIYCLFIIEMGSSLMGEFQIVPFLREVIIT" FT mRNA 6541..8560 FT CDS 8576..15385 FT /gene="L gene" FT /product="Large protein" FT /function="complexes with P protein to form RNA-dependant FT RNA polmerase" FT /db_xref="GOA:P35341" FT /db_xref="InterPro:IPR001016" FT /db_xref="InterPro:IPR014023" FT /db_xref="InterPro:IPR016269" FT /db_xref="UniProtKB/Swiss-Prot:P35341" FT /protein_id="CAA45569.1" FT /translation="MAASADILLPEVHLNSPIVKHKLVYFLLLGKLPHNLSEDEITPLH FT NQNWDQIAHEESNLSERLFAVRSELTRRIAQLRATRWRSEIAVLLWPNSLPYLCTFKPY FT NRLNTIDEWNKLVSAASNILSSPLSKCMQDISTKLIGRTNLFSRSQSRPGQSADNTITL FT NKIAAVWADNKWQPLVSLWLTIKYQMRQMIANQSKRTCSELVYVVDTRSGIIIITPELV FT TCFDKDHSVLMYFTFEMVLMISDLFEGRMNVTALCTVSNYLSPLLSRIERLFDIVDHLA FT HLLGDNVYKIIASLESLVYGCLQLHDPVIDLAGTFYSFVAQEIVDGLQQGNILSPEEAY FT TVTEQLLECFSGLSPDLTAELLCLMRLWGHPNLTAAQAAKKVRDTMCAGKVLDFQIIMK FT TLAFFHTILINGYRRKKNGIWPPLSLPGNASKSLIELHHDNSEISYEYTLRHWKELSLI FT EFKKCFDFDPGEELSIFMKDKAISAPKEDWMSVFRKSLIKQRHQRHHIPMPNPFNRRLL FT LNFIEDPSFDPAKELEYVTSGEYLRDPHFCASYSLKEKEIKPDGRIFAKLTNRMRSCQV FT IAEALLANHAGKLMKENGVVMNQISLTKSLLTMSQIGLISEKAQRYTRDNIALGALFSK FT GQRTRAHPQTQLSSIDSSQNRELPDDSLELSACFITTDLTKYCPQWRYQTIIPFAKTLN FT RMYGVPHLFEWIHLRLLRSTLYVGDPFNPPADTSVFDLDQVLNGDIFIVSPKGGIEGLC FT QKMWTMISISVIILSSAESKTRVMSMVQGDNQAIAVTTKVPRSVPLTEKRNLAYNASKL FT FFDRLKHNNFGLGHQLKAQETIISSQFFIYSKRVFYQGRILTQALKNASKLCLTADVLG FT ECTQASCSNAATTIMRLTENGVEKDVCYMLNVYQAIRQLCFDLYYPQYSIPGEQISQHY FT LKHPSIVARLVILPSQLGGLNYLSCSRLFNRNIGDPLGTAVADLKRLIKCGALESWVLS FT NLLSRKPGTGSWATLAADPYSLNIDYLYPPTTILKRHTQNTLMEVCKNPMLKGVFTDNA FT REEENNLAKFLLDRDIVLPRVAHIVIEQSSVGRKKQIQGFFDTTRTIMRKSFEIKPLSS FT KRTLSVIECNINYLAYNFNIIHHPNPIPGYLQCITTDNCSVDIARSLRKLSWSSLLNGR FT TLEGLETPDPIEVVNGALVIGVGECDYCMQGDTKFTWFFLPKGIEIDGDPEKNPPIRVP FT YVGSKTEERRVASMAYVKGATSSLKAALRGAGVFIWAYGDTDANWDDALDLANTRVQIS FT KEQLQALTPLPTSANITHRLDDGATTIKFTPASSYAFSSYTHISNDQQYLEVDNRVVDS FT NIIYQQLMITGLGIIETYNNPPIRTSSEELTLHLHTSSSCCIRPVDGCIICESPSLLPQ FT LTVPYTNPFVYDPNPLADYEIAHLDYLSYQARIGSIEHYSLQDRIDLLAHLTAKQMINS FT IIGLDESVSLLNDAVVTSDYTNNWISECSYTKIDLVFKMMAWNLLLELSFQMYYLRITT FT WSNIFDYTYMTLRRIPGNALTNIAATISHPKLLRRAMNLDVITPVHAPYLASLDYIKLS FT IDAIQWGIKQVLADLHNGIDYEILILSEDSLELSDRAMNLIARKLTLLALIQGNQLVLP FT KIKGLSPDEKCLVLTEHLMSEYQLLLLDDAELSKRSYNLTNPRITAFPSNNFYLTRKVL FT NSIRDSEEGQYLIGAYYDSFQQMETDIILHSTLIAPYDTSETLTKFDLCISLFPHDDNL FT EKYPLPVDHDSQSAVSTIVPGPPIHHVLRPLGVSSTSWYKGLSYVRYLELCKVPTGDHL FT YLAEGSGASMSLVEMLIPGQKVYYNSLFSSGENPPQRNYAPLPTQFVQSVPYKLWQADL FT TNKEGIIEDFIPLWNGNGAVTDLSNKDCVAFIIHKVGAEQASLVHVDLESTANLNQQSL FT SRSQIHALIIATTVLKRGGFLVYKTSWLPFSRLSQLACVLWSFFDKITMIRSSYSDPNS FT HEIYLVCRLAADFKTIGFSAALASAIAIAIHGDGFTTIHPDVVSNYWQHHLENVGRVGK FT AIDDVIDGVSTNFYSGDNGLILRCGGTPSSRKWLDIDLLPTFSSLQETLVNLVTVHLKE FT IIEIQTSSMEDYTSLLFTPYNIGSVGKIRTIVKLILERSLMYVIRNWLVMPSSYQDSVR FT QDLELGSFRLSSVLQEDTFWKLTENRKYLASQLTRDYITTFFTTHSILPIHRSYQKRIW FT KALGSVIYCSEVPGESQQNWDSIPLVYEEDQIERGIDGEEL" FT mRNA 8568..15431 XX SQ Sequence 15450 BP; 4708 A; 3432 C; 3190 G; 4120 T; 0 other; accaagggga gaatcagagc gggtccgacc ataacgatgt acaaaaagat atcgtaggcc 60 cggaaccagt gtgctccggt gccggttgcg attcgcacct gcacgggttg gttgaccggg 120 cctttcaatt cggactgtta tccaaattgc tctcatcatg tcgagcgttt taaagacatt 180 cgagaggttt acaatccaac aagaactcca ggatcatgag gaggataccc ctgtacctct 240 cgaaacgata agaccattga ttcgggtatt tgttgtcaac agcaatgatc ctgcattaag 300 agcacagtta ctactattta atcttagaat aatcatgagc aatacggcca gagaatccca 360 taaaacaggt gcacttctta gtatgttttc ccttcctgcc gctgccatgg gtaaccacct 420 gaagcttgcc actagatctc cagaagcaag cattgatcgg gttgaaataa caggttttga 480 agggcgatca tttagagtcg tccccgatgc aagatcaaca atgtctcggg ctgaagtatt 540 agcatacgag gcaattgcgg aagacatacc agatactctc aatcacaaaa ctccctttgt 600 gaatgcagat gtagaacaag gtgactatga cgagacagag ggatttttag aactctgcta 660 cagtgtccta atgcaggctt ggatagtaac ctgcaaatgc atgactgctc ctgaccagcc 720 cccaatctca atcgagaaga gaatggcaaa ataccaacaa cagggaagaa tcaatcctag 780 attcattctc caaccagaag caagacggat catccaaaat gccattcgga aggcaatggt 840 agttagacac ttccttacct atgaactcca aatggcacaa tctaaaaccc ttttagcaaa 900 cagatactat gctatggttg gagatgtagg caaatatatt gaacatagtg ggatgggggg 960 attcttctgt actcttaagt acgggttggg cacaaggtgg cctactctag ctctggctgc 1020 attctcagga gaattacaga agttgaaggc tctgatgttg cattatcaaa gcttaggccc 1080 tatggcgaag tatatggcac tcctggagtc accaaagcta atggattttg caccggctga 1140 gtacccgttg atgtatagct acgcaatggg aatagggact gtcatcgata caaatatgcg 1200 aaattatgcc tatgggagat cctatcttaa ccctcagtac ttccaattag gtgtagaaac 1260 tgctaggaaa caacagggtg cagttgatca ccgaactgct gaagatctcg gaatgtccca 1320 agcagataaa gtggaacttg cagcaactct tgccaagctc acaattggtc aaggtggacg 1380 tgggcgtcag cctcttgatg atccatttgc tggtgcagct ggagactacc agggtgcggc 1440 agctggaggt gcacaagggt ttgactacgc ctcccgtcgg gttagaaaat ataatgatta 1500 tgagagtgat gaggaagctg gaatggatga cgattatgag caagaggcta gagagggcag 1560 gggctatgat gatgatgatg cccgtcaagg tattggaggt caatcgggat ttgacttcag 1620 tgttcctcaa agggctccgg gaatgagtga tgaggaattc caagcacaga tgacaaagta 1680 catccagcat gtgcaacagc actatcaaga agctcaggaa ggtgcagagg atggcggcta 1740 caaccaaacc acagacgatc agggagcagg aggcgatttt gacacataat taatttaaga 1800 ttgatctact tgtaagatag caaacaatga ctgtactaga ataatccctg taatctagcc 1860 ataaaggcat actcctgcaa ctgttgattt aaagaaaaac ttaggcccgg actggtatca 1920 caccgccggc tctttcaagc gttggccaac ccttttgcct cctgctgcag tcatggcaga 1980 agagccaacc tacacggccg agcaggtcaa tgacgtagtc catgcaggac tcggaactgt 2040 ggatttcttc ctatcccgtc cagtagatgg tcaatcatcc ctgggcaagg gaagtgtgcc 2100 tccaggcata accgctgtgc tgacaaatgc tgctgagctt aaagccaaga cagctgctgc 2160 tgcccctgta aagcccaaaa gaaagaagat tcagcatatg actccagctt acaccattgc 2220 tgacaatgga gatccaaatc gtttgccagc taacacccca attgctaacc cacttatacc 2280 aattgaacgg cctcctggta ggatgactga tcttgacctg gcaactggaa cagtaacaca 2340 gggcacttat aagggcgttg aactagctaa agcagggaaa aatgcactat taacaaggtt 2400 tagttcaggt ccatcactga ccgatcaggc gtcatccaag gaccccaact ttaagagggg 2460 gggagaaatt gacggacgcc acaaaggccg acataggagg gagtggagca tcgcctgggt 2520 cggagacgaa gttaaggttt atgagtggtg caatccaaca tgtgccccag ttactgccac 2580 tgaccgcaag ttctcctgta cttgtggaac ctgccccgat aggtgcggag aatgtgaagg 2640 agataattga aatacttcga ggccttgatc tcagaatgca atctctggaa gggaaagtgg 2700 ataagattct tgcaacctcg gcaaccataa cagccttaaa gaatgaagtg acaagtctaa 2760 aagcaaatgt ggccacagtt gagggcatga tgactactat gaaaattatg gacccaagca 2820 ctccaactaa tgtaccagtt gaaaagataa gaaagaacct gaaagatact cctgttataa 2880 tctcagggcc cctgagtgag agccacatca ctgaagggag tgatatgatt gtgcttgatg 2940 aattagccag gccttctcta agttccacaa agaagattgt gaggagacct gaacccaaga 3000 aggatttaac aggtatgaaa ttaatgttga tccaactagc taatgactgt atggggaagc 3060 ctgatcaaaa ggcagaaatc gtggcaaaaa ttcatgcggc tactcgtgag gctcagctgt 3120 tagatatcaa gcgcagcatc atcaagtctg caatataaga aatcttagtt gagtacatac 3180 ctaagacaca acaataattc cactacatat atattgaatc gaagtgagca ctagggtgga 3240 taggtcaagg gacacatcta ggcatcagaa atccgagtca atctgcactg tccgggttta 3300 agaaaaaacc aagtgtcaag agcatcagat aggcacgaac ctaacacacc ccgagacaca 3360 ccagccacac acatccgggc cgaccagcag ccatgcccac catatccatc cccgctgatc 3420 ccgcatctcc agaccagggc ctaaaaccct ttccaatcca acttgactcc aaggacggga 3480 aaagtgggaa gcttgtgaag caaatcagaa tcaaatacct tactgagccc aactcaagat 3540 cacccccact tacattcatc aatacttacg gtttcatcta tgcacgagat ttgagtggtg 3600 ggatcatgaa tgagcaatca tcggggatcc agtctggatc agtaaccgcc tgcatgatga 3660 ctctaggtcc tggtcctgac attaagaacg caaacagagt cttggccgca ctgaatggat 3720 tctatgttaa agtcagaaaa acttctagcc ttaaagagga agcggtcttt gagcttgtta 3780 atgttccaaa attattggca aaccatgcac tgtgtaagca ggggagactg gtatgttctg 3840 ctgagaagtt cgttaagaac ccatctaaga tgatggccgg tcaggaatac ctgtactttc 3900 caacatttgt gtccttgact tactgtccat caaatctcaa ttatcaagtt gcgaaaccga 3960 ttctaaagat tcgatccaga tttgtctaca gtatccatat ggagattatt ttcagattgc 4020 tctgtaaacc tgattcccca ctattgaaga cttatgcaac tgatcctgaa ggcaggggct 4080 gccttgcatc agtatggatc catgtgtgta acattctcaa gaacaagaag atcaaacaaa 4140 gaggggttga tagctatttt tcaagtaagg ctatcagcat gcaactgact gtctcaattg 4200 ctgatacatg gggccccact gtgataatca aggccaacgg tcatattcct aagactgcag 4260 ctcctttctt cagtaaagat ggtgtagcat gtcaccccct tcaggatgta tcccctgctt 4320 tgacaaagtc actatggtcg gtggggtgtg agatcaccaa ggctcgacta atcttacagg 4380 aatcaaacat cagtgacctc ctcaagacac aggatttgat cactgatcag attaagatca 4440 agaaaggtca ttcacacttt ggccgatcat ccttcaaccc attcaaaaaa gctatctctt 4500 tacccaacct gacccaattg gggcaagatg atgaagatta acctccatgc aaagaaatat 4560 acaattgcat agttatagta tcctctcaat aatcagtcga gtaactaatt gtcaatatac 4620 tctaagcagt gctatcaaat ttataaattt taatcttaga ttaggtccga acccaggcac 4680 aaccgcccca caccccaccg acccgccacc gccccactca ctgccaacaa gcaatcatca 4740 aacactacat tgagtgataa tgaggctaac tccctaccct atcgctctca ctacacttat 4800 gattgcttta acaacactac ctgaaactgg attagggatt gctcgggatg ctttgagcca 4860 ggttggagtg atccaatcaa aagctagatc actgatgtac tattccgatg gaagttcaag 4920 ttttattgta gtgaaattgc tccctactct ccctactcca tctggcaatt gcaatctgac 4980 aagcattact gcttataaca ctacattatt taaattgctt acgcccctga tggaaaatct 5040 ggacaccatt gtgagtgcaa accaagctgg cagcagaaga aagagatttg ctggtgttgt 5100 tgtaggctta gctgccctgg gagtagcaac tgcagcccaa gtgaccgcag ctgtggcagt 5160 agtcaaagcc aatgccaatg cagctgctat caataagttg gctgcctcta tccagtctac 5220 caatgcagcc atctctgacg tgatatcatc aactagaaca ctagcgacag caattcaagc 5280 tgtccaagat catgtaaatg gggtgctggc aagtggcttg acagaggcaa actgtaggtc 5340 ccaagatgca ttgattggat caatcctgaa tctctatcta actgaactca ctacaatttt 5400 ccataatcaa attgtcaatc ccgcattaac tccactgtct atccaagcac tacgaataat 5460 tctaggaagc actctcccac ttattgttga atcacggtgg aatacaaatc taaatacagc 5520 agaactctta agttccgggc tattaactgg gcaaatcata tcgatctctc catcctatat 5580 gcagatggtg atccagatta cagtccctac ctttgttatg caaccagggg caaagattat 5640 cgatttagtt acaatcacgg ccaatcgaat ggaagaagag gtattgattc aagttccgcc 5700 aagaatcctt gagtatgcaa acgagattca ggcatatacc gcggatgatt gtgttgtaac 5760 ccctcatgca gtcttttgta agtacaatga cggctctccc atctctgata gcttatatca 5820 atgccttaaa gggaatttaa catcctgtgt attcactcca gtagttggaa attatcttaa 5880 gcgatttgca tttgccaatg gggtaatgta tgttaattgc aaagcccttc tatgtcgctg 5940 tgctgatccg ccaatggtca ttacgcagga cgatctagca ggaatcacag taatagacat 6000 tactgtctgt agagaagtca tgctagatac attagcattt aagattactt ctctgaacaa 6060 tgttacttat ggtgctaatt tctcaatgct ggcagcggcc atcaaagacc tctctccatt 6120 agatctttca gcccagttgg cccaagtcaa caagtcgttg gcgtctgcag aagagaaaat 6180 tgcgcagagt tcctcacttg cagcacaagc agtatcccaa gaagctacaa tcactgtcgg 6240 atcagttgca atgctcattg ctgttctcgc gctaattgct ggttgcacag ggattatgat 6300 tgcagtccag atgagccgta ggttagaggt acttaggcat ttaactgatc aaagcattat 6360 atcaaatcat cactatgctg aattgaaccc cccaccatat aaccactcct atgaatcatt 6420 acatcctatt ccacaaagcc attgattcta attacagtat aagtaagctg ttaactaccc 6480 attaatatac atgtttcttg aactaatcat tcctatatat ttaatttaag aaaaaatgat 6540 aggcacgaac ccttatggtg ccgtaacgtc tcgtggcact gggttcaaca aaaccctcgc 6600 tttagacact acatccaatt tcctttccct atccaatcaa ttacctcaca gttggtaacc 6660 cactacaaga agtcatatac actacactgg tgccgccacc atgtccggag cagagggtaa 6720 caccaacaag cggacattta gggcagtatt caggacacta atcattctta ttactctcac 6780 gatattagcc ttaagtgcgg ctattcttta tgaagtcact catacaagta atggttctga 6840 gtcaaacaac caggtgtttg accctactga cactctaaat gccattacag gaaatatcaa 6900 atcaatgatt gccctgctga atcaaatatt gtataatgca gcaattgctt taccgctcaa 6960 gattgacagt actgaatcag tcctcctcgc agcaattaaa gatttgcaat tcagtaaccc 7020 tgcctctcaa aactgctctt ctggcggaaa tttactaaat gatgcacttt acattaatgg 7080 catcaatcaa tacttgctct ctaattcatt tgcaggaact gtaggtcttg gtccactatt 7140 aaatatacca agcttcattc catctgccac tgcacctgga ggctgcacta ggatcccatc 7200 cttttcgttg acaaagacgc attggtgcta ttcacacaat gtcattctag caggatgtgc 7260 agactcaaag gcatctaatc aataccttgc gatgggtatt gttgagcagt cgtctgcaga 7320 cttcccattc ttccgtacca tgagaacgct ctacctaagc gacggtatta accgtaagag 7380 ctgctcaatt gtagccattc caggcgggtg tgctctttat tgctatgttg ctactaaaac 7440 agaacaggaa gactatgctg caactactcc ttcagagttg agattaacat tttattacta 7500 taatgaaacc ctagtagaaa ggacattgac tataccaaat gtcaccggga attgggccac 7560 acttaaccca gctgttggaa gtggagtata tcatttgggc tatcttgcat tccctgtgta 7620 tggtgggcta atacagaaca gtgcagcatg gaacagtcaa tttgggtcgt actttctccc 7680 ccaaaatcca gcagtgcagt gttccggatc agcagagcaa caaataaata ctgctaaggg 7740 gtcatatgtt gtcaattggt tctcaggacg cctaatccaa agcgcagtcc ttgtttgccc 7800 actaagcgat caactaaccg accagtgtcg agttgtgctg ttcaataatt ccgagaccat 7860 gatgggagct gaaggccggc tatacaccat tgggggtgac ctctactact atcaaagaag 7920 ctcatcctgg tggaccgcat cgttactcta caagattaac actgattttt ctcaagggct 7980 tccaccgtta attgaagcac aatgggtgcc aacctactta gtaccaaggc ctggagccca 8040 accatgcagt gcaggtaatt tttgtcctgc caactgtatt accggagtct atgctgatgt 8100 ctggcctatg aacaatccat tccctgcagg gagctcagga gtcaatccaa actacttatt 8160 tggtggggct tttctgtggg ctgacgttgc ccgtgttaat ccgacatttt atatggcttc 8220 tgctacacaa tataaaaaca ctacaggctt ccctaactcc aatcagaaag ctgcatacac 8280 tagtaccacg tgctttcaaa ataccggcag taagaaaatc tactgtttat tcataattga 8340 aatgggatcc tcgttaatgg gagagttcca gattgttcca tttttgcgtg aggtgatcat 8400 tacttaggaa ccatactcat aatatgttca aacctattac ataaccatag ttgacagcac 8460 ccactatgat tatcaagatt taagcccaat caaatccatt tctcccattt gatggtacac 8520 ttaagcaatt actacaaaga atgatttatt taaagaaaaa ttacaatagg ccagaatggc 8580 ggcctctgct gacattctgt tgcccgaagt ccatcttaac tcaccaattg ttaaacacaa 8640 gcttgtctat ttcctccttc ttggaaagct acctcataat ctttccgaag atgagattac 8700 accactacac aaccagaatt gggaccaaat tgcacatgag gaatccaacc tatctgaaag 8760 gttatttgct gtgcgcagtg agctaacacg acgaatagcc caattacggg ctacacgatg 8820 gagatcagag attgcagtcc tattatggcc caattctctc ccttaccttt gcactttcaa 8880 accatacaat cgcttaaaca ctattgatga atggaataag cttgtctctg ctgcttctaa 8940 tattttatcc tcacccctat ctaaatgtat gcaggatata tcaaccaaat tgattgggag 9000 gaccaatttg ttttctagat ctcaaagtcg cccagggcaa tcagcagata atactataac 9060 actaaataag attgctgcag tctgggcgga caacaaatgg caacccttag tgtcattatg 9120 gctgactatt aaataccaga tgaggcagat gatagcaaat caaagcaagc gcacgtgcag 9180 tgaattagtg tatgtagtag acactaggtc aggtatcata ataatcactc ccgaacttgt 9240 aacatgcttc gataaagatc actcagtact aatgtacttc actttcgaaa tggttttgat 9300 gatctctgac ctatttgagg gtcgtatgaa tgtcacagct ctttgcactg ttagtaacta 9360 cctcagccct ttactatccc gaattgagag actatttgat attgttgatc acttggctca 9420 cctattagga gataatgtgt ataaaataat agcatcttta gaatcattgg tctatggttg 9480 tttgcagctg catgatcccg tcattgacct tgcaggaaca ttttactcct tcgttgccca 9540 agagatagta gatggattgc agcaaggtaa catattaagc ccagaagaag catacaccgt 9600 cactgaacaa ctattagaat gcttcagtgg cctttccccc gacctcactg cagaattact 9660 atgtttgatg agattatggg gacatcccaa cctcactgct gcacaagctg caaaaaaagt 9720 cagagacaca atgtgtgccg gtaaagtact tgacttccaa ataattatga aaaccctagc 9780 tttcttccat acaattctta tcaacgggta cagaagaaag aaaaatggga tttggccacc 9840 actcagtctc ccagggaatg ccagtaaaag tttgattgag ctccaccatg ataactctga 9900 aatctcttat gaatacaccc tacgtcattg gaaagaatta tccctcatag aattcaaaaa 9960 atgtttcgat tttgacccag gagaggagct aagcatattc atgaaggata aggctataag 10020 tgcaccaaaa gaggattgga tgagtgtttt ccggaaaagt ttaatcaagc agagacatca 10080 gcgtcatcac atcccaatgc ctaacccctt caatcgacgg ctactcttaa attttataga 10140 ggacccgtca tttgaccccg ccaaggagtt agagtatgtt acaagtggtg aatacttaag 10200 ggatccacac ttttgtgcat catactcact aaaggagaaa gagattaaac cagatggaag 10260 aatctttgct aagttaacta accgcatgag gtcctgtcaa gttatagctg aagcactgtt 10320 agcaaatcat gctgggaaac tcatgaaaga aaatggtgtg gtcatgaatc agatatccct 10380 aaccaaatca ttactaacaa tgagtcaaat cggattaata tctgagaaag cacaacggta 10440 tacacgagat aatattgctc taggtgcctt attttctaaa ggacaaagga ctagagctca 10500 tcctcaaaca caactaagca gtatagattc atcccagaac agggagcttc ctgatgactc 10560 attagaattg agtgcctgct tcatcacaac agatcttact aaatactgtc cgcagtggag 10620 gtatcaaact ataatccctt ttgccaaaac acttaataga atgtatggtg taccacattt 10680 gtttgaatgg atccacctaa ggctattgag gtctaccctc tatgtagggg acccatttaa 10740 tccaccagct gacactagtg tgtttgatct ggatcaggtg ttgaatggtg acatattcat 10800 cgtgtcacca aaaggaggta tagagggctt atgccaaaaa atgtggacga tgatatccat 10860 ctcagtaatt attctctctt ctgcagaatc taaaactcga gtaatgagta tggttcaggg 10920 agataaccaa gcaatagctg taacaacaaa ggttccaagg tcagttcctc tcactgaaaa 10980 gaggaaccta gcctataatg caagcaaact gttttttgat cggctaaaac ataacaattt 11040 tggactaggt catcagctta aagcacagga aacaattatc agttctcaat tcttcatcta 11100 cagtaaaagg gttttttatc agggtaggat cctaactcag gctctcaaga atgctagcaa 11160 actgtgtcta accgcggatg tcttagggga gtgcactcaa gcatcttgtt caaatgcagc 11220 tacaacgatt atgagattaa ctgagaatgg agtggagaag gatgtgtgct acatgctcaa 11280 tgtttaccaa gcaataagac aattatgttt tgacctgtat tatcctcagt acagtatccc 11340 cggagaacaa attagccaac attatctcaa gcatccgagt atagttgccc ggctagttat 11400 attaccatct cagttgggtg gcttgaacta cctgtcctgt agccgactat ttaacaggaa 11460 tatcggtgat ccactaggaa ctgctgttgc agacctaaag aggctgatta agtgtggagc 11520 attagaaagt tgggtattat caaacttatt atcccgtaaa ccaggtactg gttcctgggc 11580 aacccttgct gctgatccat actctctgaa catagactac ctatacccac caaccactat 11640 tctcaaacgg catactcaaa acaccctcat ggaggtgtgc aaaaacccaa tgctgaaggg 11700 tgtcttcacc gacaacgccc gagaagagga gaacaatctt gctaaatttc tacttgacag 11760 ggatatagta ctacctcggg tggcgcacat tgtgattgag cagtcaagtg tgggcagaaa 11820 gaagcaaatc cagggcttct ttgacacgac taggaccatc atgaggaaat cttttgagat 11880 aaagccattg tcatctaaga ggactctttc agtaatcgag tgtaatatta actatttagc 11940 atacaacttc aacataatcc atcaccccaa ccccatccca ggttacttac agtgtattac 12000 cacagacaat tgcagtgttg atatcgcaag gagtctcaga aaattgtcat ggtcttctct 12060 cttgaacgga aggactttgg aaggattaga gacacctgac ccaatagaag tagtcaatgg 12120 tgcactagtt ataggagtgg gtgaatgcga ctactgcatg caaggagata caaaattcac 12180 ttggttcttt ctaccaaaag gtatagagat agatggggat ccagaaaaga acccaccaat 12240 tcgcgtccca tatgttgggt caaaaacaga agagagacgt gttgcctcaa tggcttatgt 12300 taaaggggcg actagtagcc ttaaggccgc tctcagagga gcgggggtat tcatctgggc 12360 ctatggagac actgatgcta actgggacga tgccttggat ctagcaaaca caagagtaca 12420 aatatcaaaa gaacaactgc aagctctgac accgttaccc acttcagcta atatcaccca 12480 caggttagat gatggagcga ctacaattaa gttcacccca gcgagttctt atgctttttc 12540 tagttatacc catatctcta atgatcagca gtaccttgaa gtagacaata gagtggttga 12600 ctctaacatc atttatcagc aactcatgat cactggccta ggtattatag aaacatacaa 12660 caatccaccc ataaggactt caagtgaaga gctgactctc catctgcata ctagttcttc 12720 ctgttgtata agacctgtag atgggtgcat catatgtgaa agcccatcct tattgcctca 12780 attaactgtg ccatatacca acccatttgt gtacgaccct aatcctttag cagactacga 12840 aatagcacac ctcgattact tatcttacca ggctcggata gggagtattg aacattactc 12900 ccttcaggat aggattgatt tattagccca tctcactgca aagcaaatga ttaactctat 12960 aataggactg gatgaatcag tgtcccttct caatgatgcg gttgttactt ctgattacac 13020 aaataactgg atcagtgagt gttcatacac taagatagac ttagtattta agatgatggc 13080 atggaatcta ctgctagagt tgtcattcca aatgtactat ttgaggatta ctacctggag 13140 caatatattc gattacactt atatgaccct taggcgtatt ccggggaatg ctctcacaaa 13200 tatagcagct accatcagcc acccaaaact tcttcgacga gccatgaacc ttgatgttat 13260 aacacctgtc catgcaccat atttagcatc tttagattac ataaaattaa gtatagatgc 13320 aattcagtgg ggtatcaaac aagttctagc tgatctacac aatggaattg actatgaaat 13380 acttatactg tctgaggatt ctttggagtt gagtgatcgg gccatgaacc taatcgcacg 13440 gaagttaaca ttgctggctt taatacaagg aaaccaactc gtgctgccaa agattaaagg 13500 gttgtcccca gatgaaaaat gcttagtact aacagaacat ttaatgtcag agtaccaatt 13560 attgttgtta gatgatgcag aacttagtaa gcgtagttac aacttaacta atcctaggat 13620 taccgctttc ccaagcaata acttttatct gactcgaaag gtccttaata gcatacggga 13680 ttctgaggag gggcaatacc ttattggggc atattatgat tcattccagc aaatggagac 13740 cgatattatt ttgcactcta cccttatagc tccatatgac acaagtgaga ctttaaccaa 13800 atttgatcta tgtatctctc tctttcctca tgatgataac ctcgaaaaat acccattacc 13860 tgtagatcat gactcgcaat cagcagtgtc tacaatagtt cctggaccac caatacacca 13920 tgtactacgg cccttagggg tttcctcaac atcatggtac aaaggactca gttatgttag 13980 gtacctggaa ctatgtaaag tcccaaccgg tgatcatcta tatcttgcag aaggcagtgg 14040 agcatccatg tcattagtgg aaatgctaat cccaggtcaa aaagtgtatt acaatagtct 14100 ctttagcagt ggtgagaatc ctccccagag aaactatgcc ccattaccaa ctcaatttgt 14160 acaaagtgta ccatacaaat tatggcaggc agatctcact aacaaagaag gtataattga 14220 agactttata ccactatgga atggaaatgg tgcagtgacc gatctgagta acaaggattg 14280 tgttgctttt atcatacata aggtaggagc agagcaagca tcgttagttc atgttgacct 14340 agagtcaact gcaaacctga atcaacaatc cctttcaagg tctcagatac atgccctgat 14400 aatagctacc acagtattga aaagaggagg cttcctagtg tataaaacct cgtggctccc 14460 attttctaga ttaagccaat tggcttgtgt gttatggtcc ttttttgata aaatcaccat 14520 gattcgtagc agctactctg acccaaatag ccatgaaata tatctagtct gtcgccttgc 14580 tgccgatttc aaaaccatag gctttagtgc tgcactcgca tctgcaatag caatagcaat 14640 acatggggat ggttttacaa ccattcatcc tgatgtcgtc agtaattatt ggcaacatca 14700 ccttgagaac gtcgggcggg ttgggaaggc aatagatgat gtaatagatg gcgtatccac 14760 taatttctat tctggagata acggattaat cctccgttgt ggaggaacac ctagttcacg 14820 aaaatggttg gatatagatc ttctcccaac attctcttct ctacaggaga cattggtaaa 14880 tctggtgaca gttcacctca aagagattat tgaaattcaa acttcatcta tggaggatta 14940 tacctcctta ttgtttacac cctataatat tgggtcagtt gggaaaatta ggactattgt 15000 taagcttatc ctagagagat ctttgatgta tgtaatcagg aattggttag tcatgccatc 15060 atcttatcag gacagcgtta gacaagactt ggaattagga tctttccgac tgtcttccgt 15120 actacaggaa gatacatttt ggaaattgac agagaatcgt aaatacttag caagccagct 15180 tacaagagat tatatcacca cattctttac tacgcattct atcctcccaa ttcacaggtc 15240 gtatcaaaaa cgcatttgga aagccttagg gagtgtgatt tactgttcag aagttccagg 15300 ggaaagccag caaaattggg attccattcc attagtttat gaggaagatc agattgagcg 15360 cggtatcgat ggggaagagc tgtagaaaca ctttaatcaa cagttgaaga cagttttaat 15420 ttaagaaaaa atatccgttc tccccttggt 15450 // |
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