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EBI DbfetchID X60325; SV 1; linear; genomic DNA; STD; INV; 8333 BP. XX AC X60325; XX DT 07-JAN-1992 (Rel. 30, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 14) XX DE G.lamblia rpoA3 gene for subunit A of DNA dependent RNA polymerase III XX KW DNA-dependent RNA polymerase III; rpoA3 gene; subunit A. XX OS Giardia intestinalis OC Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia. XX RN [1] RC revised by [3] RP 1-8332 RA Lanzendoerfer M.; RT ; RL Submitted (23-SEP-1991) to the EMBL/GenBank/DDBJ databases. RL M. Lanzendoerfer, Max-Planck-Insitut f, Biochemie, Am Klopferspitz 18, RL D-8033 Martinsried, FRG XX RN [2] RP 1-8332 RX DOI; 10.1093/nar/20.5.1145 RX PUBMED; 1549483. RA Lanzendoerfer M., Palm P., Grampp B., Peattie D.A., Zillig W.; RT "Nucleotide sequence of the gene encoding the largest subunit of the RT DNA-dependent RNA polymerase III of Giardia lamblia"; RL Nucleic Acids Res. 20(5):1145-1145(1992). XX RN [3] RP 1-8333 RA Lanzendorfer M., Palm P.; RT ; RL Submitted (23-JAN-1992) to the EMBL/GenBank/DDBJ databases. XX FH Key Location/Qualifiers FH FT source 1..8333 FT /organism="Giardia intestinalis" FT /strain="ssp. P1" FT /mol_type="genomic DNA" FT /db_xref="taxon:5741" FT CDS 1439..3025 FT /gene="ORF" FT /db_xref="UniProtKB/Swiss-Prot:P25203" FT /protein_id="CAA42894.1" FT /translation="MKQYALHKELVQKAVEGADGYSIILGIVSCGEGLRLLVAMNCLWP FT GAGSIQTLLCGLPSLPPCPESRDILRALFQSIGAADCMPDMAQRHHTFLHKLTLISIYE FT SSNLKYDEVKQALRKARQDVVEDVPLPVFKVILFPQLSFLRDALSVHCDLFTVVTVLLE FT SLVDTAPDGWHLDAAEADCSTNAFNFDSGEVKEDRLWGEMRTLITKFSEAQHQLDYLSL FT IDLKAILRLIREHKETLIHTMMAVSVTNPLSQQCIPSLTDSKWLQHAHFIEGLVTLLAP FT FESMLTAPNACAFDVYAHLDRLRSILRDARDMLPCAVPDFLSMDRKCARALHSDNIAPE FT EAHFYFTILSIYIDEIDSILDCYSPYVSGFKLCTFTLGTVTLSEITSSLSSLPCKLTNL FT AQIAEEYYFIYQSEQIADCLSTLQSVNRCEDVYEHWKTLVTFWSRLLREYSLASRLMLL FT LLTAFSTPAIFLASKTVISSALSAQRSCLTEANSEAALLLHLKHGFIVKTLFKFILKQP FT IGGGLLRDGAE" FT CDS 3012..8237 FT /gene="rpoA3" FT /product="subunit A of DNA dependent RNA polymerase III" FT /db_xref="GOA:P25202" FT /db_xref="HSSP:1I6H" FT /db_xref="InterPro:IPR007081" FT /db_xref="UniProtKB/Swiss-Prot:P25202" FT /protein_id="CAA42895.1" FT /translation="MEPNRRLRYFRSEIPQPVTEHRFPKRVEKLVFSVLSSNALMKLSE FT VQITTPILYEHYPSPATNGVLDKRLGLSDKVGKCATCGKDTKMCIGHFGTISLALPVFH FT PGLINDARTMLSIVCPFCSRVKISEADRLKYKVLNHKFSLAIVKEAQEQAKKQVNCPFC FT HAPSTICKKSQGFRVLREMHYEERATKILADVIKHQKDIEKIQELDQRLRNHVVDPIQA FT LHILQKVPECDYPYLGIPWQSRNVYASQQTPDSIASNDASQLFSRGSSKLLARTASRFI FT AQHQGISDRATRLTSHAFLTRPQDVILTHIPVPPSCLRPSVQSGSGAGTTEDNLTSHLV FT RILTINDKLKEAMVSGAVATSKVYAKWDQLNMDVSLLYIGKIPGGVQPVKNKTDSGTKE FT GTGIIDRLKGKAGRFRSNLSGKRVNFSGRTVISPNPYLSMQQVAIPRLIAQNLTFPEIV FT TSRNIRFLRELILNGKTYPGANEVLLLNDTIRYNPALKRLGIDVKQSRDMEAKAMELVS FT RCVDTFNLNSLCADLPELQAAIQHLVSESSNAINSELKAEDLPQNQPLFAKEVYDPAQK FT GESNNIDNNVCEIDELKLEDTADYQVGESAGQASTVAVEQPPESRTVLKLNSIASLQLT FT NASSQHLSTFKLNTVSLLQKDRRGRQAIANSLRPNDIVYRHLLPNDTLLFNRQPSLHRM FT SIMQFNAVIHENRTFSFNPVVCSPFNADFDGDEMNIFYMQGQEARAEAGILMGSHENII FT SPRHGECMIGLTQDFLTGIYLLSGKGIFMTRQEYCQHVSYGCDGFGDATYGVSLYNYGR FT EFIKSIHDRRGTEEDTVGFVKVPCLSQPCIVYPRQLYSGKQVLSVLMKGNDFDSVNINL FT EHGDKTYKKDSDRRALSVNDDYIIIQNSEHLVGRLTKTFLASSKNCIFYFLVQNYGPVS FT AARIMLRFAKVAARFLMNYGFTIGIDDVMPSQRVLGKKEVIVQEGYEKAQEKIRDYESG FT KLEAIPGSTVQETLEATLNQILSNVRESCAQIALKELHFTNKPLIMSLCGSKGSPINIA FT QMIIILGQQSFGGSRAPDDFYTRSTPYFYHYSKEPNAKGFILNSFYTGLLPFEFLAHAR FT AGRDGVIDSACKTADTGYLQRRLVKCLEDLSVSYDFTVRNSKKSVVQFRFGHDGFDPIK FT LEVGTGQCFDLDTLLRHIILLNRSQDLAEGAFPVLLDRYKAEAELDVLLNKDFYGQEAC FT LIERSNVTSYFQQSILPKLTTNTHIATTVAPALAASFLQTTLTKKDIDDFLRQVRRKYI FT RLNLEPGSPCGAVAAQSVGEPSTQMTLKSFHHAGLASMNITQGVPRLKEIVDGVVKIST FT PITTVELHVDVDKEELAATVTEKYLEKARMMKNIIECTYLGQISASIIECYSQSVCHIE FT VNLDMKIIADMGLAGIITVETVVASILHNDKAKKLVGQDQSSGSVSIHSATRFSVRPLT FT QSRDDLLFDIQSLKLLLPMIPVSGISTCSRAVINEYKEFCQGATSSAPLTKYNLLVEGI FT GLQNILNVSGIDFTRTLSNNIVEVANTLGIEAAVATISNEIKACMDSHGMAVDMRHIRL FT LADIMCFRGRVLGFTRFGLTKMKADSVIMLASFEKTGEHLFNAALGNKVDEANGVTESI FT ILGKPMSMGTGSFSLLQAPYFDEKTGKTIEYQPKQTTRFLGEVLNKQYDEEVDAIVNAF FT WYDEKLYLTGAEAKAKLLRGRRHANKRSWSRGKERHASLKPKNR" FT old_sequence 8216 FT /replace="" FT /citation=[1] XX SQ Sequence 8333 BP; 2281 A; 1944 C; 1991 G; 2116 T; 1 other; ctgcagtgtg tcgcaaacag tctcggtgag atttttgaag gtacctgttg tttgttgaag 60 ctggggcatg gagcccgtat taagctgagc tagtagtgaa gagaaagaag aggtgtggta 120 gaaactccta tcaggattgc tactgtggtc gatcatgact gaatagggag tattgctagt 180 ttgcaagtca tagagtcttt cgcaatagac ttcaaggaag cttaacttta ccatgaagcc 240 gaggttataa atgcgacgca aaccctgtat gatgagtcct tctttgttag actggagcag 300 agtagggtcc caatcattcc ctggctcaat gggggagctt ttcttggcag agaaccctcg 360 tttgcgccga gtatcgctca gaaaaagatg ctcatctccc agaatggtat atgttttgcc 420 agagtttgtc tggccataag caataacagc agatatgcat ccgccgatgg ccttatcaat 480 cacaggtggt aaaatagagt cagctacctc tccattagta acttcttcgc tgaataactg 540 gggaatacca aacagtagtt tggctccatt atatgccagt cctatctgcc tgccctcgct 600 gacaagctca caagagcgct tttcggtgga gaacaacggt cttgcacgaa cagcaacatg 660 aataggcata aaaagctcgg gttgcgctta tctcttggtt ttgcgtcgct gaatgagtct 720 tgttaaaata attgaatagg ttggaaaatg tcgttttttg gggcgctcaa acgctgaggg 780 cattctacaa tgctcttcca taatttgact tctgtcacag aggagactgc cagcagcgta 840 gttagcaatg ttgaaaagtg gcacgacatc tttgggtcca tagcttccgt agtaacaata 900 gataatgcta gcacggcccc ctgtgcacgg cgctgtggag gggtcatgga tgggcgctat 960 agtgatctag aaacctatta tgcctgtaga gtagcccgca actcaaccag gacacctgat 1020 ctgcacaata tgcagcgcag aaaaagggcg tgcttacttt tttaagggag gcccggccac 1080 tggaaggaag cacttncttc gatgccacaa gagtattgca acgatgtatc caatggtgga 1140 tgaggcgtcc cggaaggagc gtgaaatggc gttgagatac tttatagatg aagcaaggca 1200 aaagaaacag tgtgcatggc ccaaaggctc tagtgctgat ccagttggta gatgtttatg 1260 cgatgcaatt ctcgcccacg ggcttgctta ttctcaaggc ccagtcatta agtagctact 1320 cacaaaggtt atcaatgttg tggctaggat cgaagggtat tctcctgagc ttcaggataa 1380 gctgctgcga gcagtttctg tggcacggat atctagaagc accatccagc gacgtggaat 1440 gaagcaatat gccctccata aggaactggt tcagaaagca gtagaaggtg cagacggata 1500 tagtatcatt ttaggaatag tgtcatgtgg agaggggctg cgtcttcttg tagcaatgaa 1560 ttgtctttgg ccaggagctg gctcaattca aaccctattg tgtggtcttc ctagcctccc 1620 gccttgtccg gaatcaaggg atatattacg tgcactcttt caaagcatag gtgcagcgga 1680 ttgcatgcca gatatggccc aacgacacca tacttttctt cataaactga ccttgatatc 1740 tatttatgaa agctctaatt tgaaatacga tgaggttaag caagcattaa ggaaagcaag 1800 acaggacgtt gtggaagatg tgcctctccc agtctttaag gttatcttat ttcctcaact 1860 ttcctttctt agagacgctt taagtgtgca ctgtgatttg tttaccgtcg tcaccgtact 1920 cttagagagc ttggttgaca ctgcaccaga tggatggcat cttgatgctg cggaagctga 1980 ttgctccact aatgccttta actttgatag tggcgaggtc aaagaggatc gtttatgggg 2040 tgaaatgcgc actctaatca ctaagttttc tgaagcacaa catcagctgg attatttgtc 2100 gttgattgat ctgaaggcaa tcttaagatt gattcgggag cataaagaaa cactcattca 2160 cacaatgatg gccgtatccg tgactaatcc tctgtcgcag caatgcatac ctagtcttac 2220 tgactccaag tggctccaac atgcacactt tatagagggc cttgtaacgc tgttagctcc 2280 gtttgaaagc atgctgaccg caccgaatgc atgcgccttt gatgtatatg cccaccttga 2340 tagacttcgc tcgattctcc gtgacgctcg cgacatgctg ccatgtgctg tacccgactt 2400 tctatccatg gatcggaagt gtgccagagc gctccacagc gataatatag cgccagaaga 2460 ggcgcatttt tactttacta tactgtcaat ctacatagat gagatagact caatcctgga 2520 ttgctactct ccatatgttt ccggcttcaa gttatgcaca ttcacgctag gcactgtcac 2580 tcttagcgag ataacaagca gcttaagtag ccttccctgc aaactaacca acttagccca 2640 gatagcggag gaatattatt ttatatacca atccgaacag attgcagatt gccttagtac 2700 actacaaagt gtcaaccgat gtgaagatgt atatgagcat tggaagactc ttgttacttt 2760 ctggtctagg ttgttacgtg agtactcatt ggctagcagg cttatgttac ttctgctgac 2820 cgcattttcc accccggcca tcttccttgc ttcgaagact gtaataagca gcgctttgtc 2880 tgcccagcgg tcctgtctaa cagaagcgaa ctcagaggct gctcttcttt tgcatctaaa 2940 acatggcttc atagtaaaaa cattgttcaa atttatatta aaacagccaa ttggaggcgg 3000 cttacttaga gatggagccg aataggcgct tgcgatactt caggtctgaa ataccacagc 3060 ccgtcacgga gcaccgcttt cccaagcgcg tggagaagct tgttttctca gtgttgtcat 3120 cgaatgccct catgaagttg tccgaggttc aaatcacaac accgattctt tacgagcact 3180 acccctcccc agcaaccaac ggggtgctgg acaaaaggct tggtctatcg gacaaagttg 3240 gaaagtgcgc gacttgcggc aaggacacga aaatgtgcat aggacacttt ggaacaattt 3300 ccctggccct tcctgtcttc catcctggcc taatcaacga tgcaagaact atgctctcta 3360 ttgtctgtcc gttttgcagc cgcgtaaaga tctctgaagc cgacagactc aagtacaagg 3420 ttctaaacca caagttttct cttgccattg tcaaagaagc ccaggagcag gcgaagaagc 3480 aggtgaactg cccgttctgc catgccccaa gcacaatttg caagaaatca cagggattcc 3540 gggttctaag agagatgcat tacgaagagc gtgctactaa gattcttgca gacgtcatca 3600 agcaccagaa ggatattgaa aagatccaag agcttgacca gcggcttcgg aatcacgttg 3660 tggatccaat acaagcactt cacatcctcc agaaggttcc cgagtgcgac tatccctacc 3720 taggaatacc ctggcagtca agaaacgtgt atgcgtccca gcaaacccct gattctattg 3780 ccagcaatga cgctagccag ttattttcca gaggctcgtc caagctactc gcaagaacgg 3840 cgagtcgctt tattgcacag catcagggga taagcgatcg tgccacacgt ttaacatctc 3900 atgccttcct gaccaggcct caagacgtta ttttgactca tatccctgtg cctccgtctt 3960 gcctccgccc ctctgtacaa tcagggtctg gtgctggaac aacagaagac aacctcactt 4020 cccaccttgt tcgcatttta accattaacg acaaactgaa ggaagcgatg gtctccgggg 4080 ccgtagcaac ctcaaaagtg tatgcaaaat gggatcagct taatatggac gtttctctac 4140 tatatatagg gaaaatccca ggcggcgtgc agcctgtgaa gaataagacg gattctggca 4200 ccaaagaggg aacggggatt attgataggc tgaagggaaa agcaggaaga tttaggtcta 4260 acctcagcgg aaaacgggtc aacttcagtg ggaggactgt catttctcca aacccatacc 4320 tttctatgca gcaggtggca attccccgcc tcatcgccca aaaccttacc tttccagaga 4380 tagtaacgtc tcggaatatt cgctttttac gtgagcttat tcttaatggg aagacctatc 4440 cgggagccaa tgaagttctt ctattgaacg acaccattag atacaatcca gcactcaagc 4500 ggctcggaat tgacgtgaag caaagccgag atatggaggc aaaggctatg gaactggttt 4560 cgcgctgtgt tgacacgttt aatctcaatt cgctttgtgc agacctccca gagctccagg 4620 ctgccattca gcaccttgtt agcgagtcca gtaacgcaat aaatagtgag ctcaaggcag 4680 aagatctgcc acagaaccag ccgctttttg ccaaggaggt gtatgatcca gcacagaaag 4740 gtgaatcaaa caatatagac aacaacgttt gtgagataga tgagctgaag cttgaagaca 4800 cagctgatta tcaggtaggt gagtcagctg gccaagcttc aactgttgca gtcgagcagc 4860 caccggagtc aaggaccgtt ctaaaattga actcaatcgc atcgttgcag cttaccaacg 4920 cgtcgtcaca gcacctatcg accttcaaat taaacactgt ttctctgctc caaaaagatc 4980 gccgtgggcg ccaggctatt gccaatagtc tcaggcccaa cgacatagtt tatcggcatt 5040 tgcttcccaa cgatacttta ctctttaacc gtcagccgtc ccttcacaga atgtcaatca 5100 tgcaatttaa tgcagttata cacgaaaacc gtactttttc tttcaatcca gttgtctgct 5160 ctccatttaa tgcagatttc gacggggacg agatgaatat cttttacatg caaggccagg 5220 aggcgcgtgc tgaagcgggg atcctcatgg gctctcacga aaacattatt tcgccacgac 5280 atggagaatg catgattggg ctcacgcagg attttctaac aggaatctac cttctcagcg 5340 gcaagggcat cttcatgaca cgccaagagt actgccagca tgtgtcctat ggctgtgatg 5400 gctttgggga tgccacatat ggtgttagtt tgtacaacta tggtcgcgag ttcattaaaa 5460 gcattcatga caggagaggt acagaggaag acaccgttgg gtttgttaag gtcccctgtc 5520 tttcacagcc atgcatagtg taccctcgac agctctatag cggaaagcag gtgctctctg 5580 ttctcatgaa gggaaacgat tttgactctg tgaacatcaa tctagagcac ggtgacaaga 5640 catacaagaa agacagtgac aggcgtgcac tctccgtcaa cgatgactat atcatcatcc 5700 agaattcaga gcacctcgta gggcgtctca ccaaaacgtt cttggcatcg tccaagaatt 5760 gcatattcta ttttttggta cagaactatg gtcctgtttc agcagctcgc atcatgctcc 5820 gcttcgccaa ggtggctgct agatttctta tgaactatgg cttcaccata ggcatagatg 5880 atgtaatgcc atcccagcga gtgctgggta agaaggaggt aatagttcag gaaggttatg 5940 agaaggcgca ggaaaagatc cgtgactacg aaagcggaaa gctagaggct atacctgggt 6000 ctactgtgca agagacgctt gaagcaacac ttaatcagat cctgtccaac gtccgcgagt 6060 cctgcgccca aatagctctc aaggagcttc acttcaccaa taagcctctc atcatgtcac 6120 tctgtgggag caagggaagc cccatcaaca tcgcccagat gattattatt cttggacaac 6180 aatcctttgg aggatctagg gcgcctgatg acttctacac tcgctcaact ccatatttct 6240 atcattattc aaaagagccg aacgcaaaag ggtttatcct gaacagcttt tatactggct 6300 tgcttccatt tgaattctta gcgcacgcac gagcaggccg agatggggtc attgactctg 6360 cctgcaaaac agcagataca gggtatttgc agcgacggct tgttaagtgt ctagaggatc 6420 ttagtgtgtc atatgatttt accgtgcgca acagcaagaa gagcgtggtg caattccggt 6480 ttggacacga tgggtttgat ccaataaagc tcgaagttgg gactgggcag tgcttcgatc 6540 tagacacttt gctcagacat ataatcttgc ttaacagatc acaagatctg gccgaggggg 6600 ccttccctgt tcttctggat cggtacaagg cagaggcaga gctagacgtc ctcctgaaca 6660 aagactttta cggccaggag gcttgtttga ttgaaagaag caatgtcact agctatttcc 6720 agcagagcat attgccaaaa ttaactacga acacacacat cgccactact gtggccccag 6780 cacttgcagc atcattcctc caaacaaccc ttaccaaaaa ggacatagat gattttctaa 6840 ggcaggttcg gcgaaagtac attcgcctga atctggaacc gggatctcca tgcggtgcgg 6900 tggccgccca gtcagtcggg gagccctcca ctcagatgac actgaagtca tttcaccacg 6960 caggcttagc ttccatgaac ataacgcaag gggtcccacg gctgaaagaa attgtcgatg 7020 gtgtggtaaa gatatccaca ccaatcacaa ccgtggagct ccatgtagat gtagataagg 7080 aggaactggc agcaacggtg acagaaaaat atcttgaaaa agcgcgcatg atgaagaaca 7140 tcatcgaatg cacgtacctt ggccagatat ctgcatccat tatcgagtgc tacagccaat 7200 cagtttgcca cattgaagtc aatttggata tgaaaataat cgcagacatg gggcttgctg 7260 ggatcataac ggtagagacg gtggtagcgt ccatcttaca caacgataag gcgaaaaagc 7320 tagtaggaca ggaccaatct tctggatcgg taagcataca cagtgccaca aggttctctg 7380 tccgcccctt gacgcagtcc agagacgact tgctcttcga cattcagagc ttgaagttac 7440 tccttccaat gatacccgtt tctggcatat ctacttgtag tcgcgcggtg atcaatgagt 7500 ataaagagtt ctgccaaggc gccacaagca gtgcaccgct aactaagtac aatctccttg 7560 tggagggtat tgggttacaa aacatcctaa atgtcagtgg aattgacttt acacgcactc 7620 tgtccaataa tatcgtagag gtagcaaata ctcttgggat agaggctgca gtggccacaa 7680 tatccaacga gataaaggcc tgtatggata gccatggtat ggccgtagat atgcgacata 7740 tccgccttct tgcagacatt atgtgcttca ggggccgagt gctaggcttt acaaggtttg 7800 gcttgacaaa gatgaaggcc gattccgtaa tcatgcttgc aagcttcgaa aagactggtg 7860 agcacctgtt taatgctgca ctagggaata aggttgacga agcaaacggt gttacagagt 7920 ctatcatact agggaaaccg atgagtatgg gaacaggatc attctcgcta ttgcaggcac 7980 cgtactttga tgaaaaaacg ggcaagacga ttgagtacca gcctaagcag acaacccgct 8040 ttctagggga ggtcctaaat aaacagtacg atgaagaggt ggacgctata gttaacgcgt 8100 tttggtacga cgaaaagctt tatctaacgg gtgcggaggc taaggcaaag cttcttcgtg 8160 gaaggcggca tgcaaataag cgctcctggt cgcggggaaa agaaagacac gctagtttga 8220 agccaaagaa tcgataatat tgcgtttctg ttcatcactt aagctacacg tgcacagaat 8280 cttttctgcg tgagcaactg taactctctc gtatggaaga agccttgtga tca 8333 // |
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