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EBI DbfetchID X58793; SV 1; linear; genomic DNA; STD; PRO; 2815 BP. XX AC X58793; S67525; XX DT 19-JUL-1991 (Rel. 28, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 31) XX DE S.lividans cutR gene and cutS gene XX KW cutR gene; cutR protein; cutS gene; cutS protein. XX OS Streptomyces lividans OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptomycineae; Streptomycetaceae; Streptomyces. XX RN [1] RC Revised by [4] RA Chen C.W.; RT ; RL Submitted (09-APR-1991) to the EMBL/GenBank/DDBJ databases. RL C.W. Chen, Institute of Genetics, National Yang-Ming Medical College, RL Shih-Pai Taipei, Taiwan XX RN [2] RX DOI; 10.1111/j.1365-2958.1991.tb01892.x RX PUBMED; 1956295. RA Tseng H.C., Chen C.W.; RT "A cloned ompR-like gene of Streptomyces lividans 66 suppresses defective RT melC1, a putative copper-transfer gene"; RL Mol. Microbiol. 5(5):1187-1196(1991). XX RN [3] RP 1-2815 RX PUBMED; 8885276. RA Chang H.M., Chen M.Y., Shieh Y.T., Bibb M.J., Chen C.W.; RT "The cutRS signal transduction system of Streptomyces lividans represses RT the biosynthesis of the polyketide antibiotic actinorhodin"; RL Mol. Microbiol. 21(5):1075-1085(1996). XX RN [4] RP 1-2815 RA Chen C.W.; RT ; RL Submitted (18-APR-1996) to the EMBL/GenBank/DDBJ databases. RL C.W. Chen, Institute of Genetics, National Yang-Ming University, Shih-Pai RL Taipei, Taiwan XX CC CutR and CutS belong to the two-component family of bacterial CC signal transduction systems. CutR and CutS are response regulator CC and histidine protein kinase, respectively. This operon represses CC actinorhodin biosynthesis in Streptomyces lividans 66 and S CC coelicolor A3(2) XX FH Key Location/Qualifiers FH FT source 1..2815 FT /organism="Streptomyces lividans" FT /strain="66" FT /isolate="HT32" FT /mol_type="genomic DNA" FT /clone="su175" FT /db_xref="taxon:1916" FT mRNA 382..>1111 FT /gene="cutR" FT RBS 445..449 FT CDS 458..1111 FT /transl_table=11 FT /gene="cutR" FT /product="cutR protein" FT /db_xref="GOA:P0A4I2" FT /db_xref="HSSP:1KGS" FT /db_xref="InterPro:IPR001789" FT /db_xref="UniProtKB/Swiss-Prot:P0A4I2" FT /protein_id="CAA41599.1" FT /translation="MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERIGVNDY FT DVVVLDRDLPLVHGDDVCRKIVELGMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFA FT FSELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGKEVQLAPKEFAVLEVLMR FT SEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPPVIVTVPGSGYRI" FT mRNA 383..>2362 FT /gene="cutS" FT CDS 1118..2362 FT /transl_table=11 FT /gene="cutS" FT /product="cutS protein" FT /db_xref="GOA:P0A4I8" FT /db_xref="HSSP:1BXD" FT /db_xref="InterPro:IPR004358" FT /db_xref="UniProtKB/Swiss-Prot:P0A4I8" FT /protein_id="CAA41600.1" FT /translation="MATTPAPPGAPPKPTWDPRSATPLPWLRPTIRIRLTLLYGGMFLI FT AGILLLSIIYLLAAQAVRTGNEPLYKIVDFTDLKVSSSTCPVVDNGGLSLSDFNAAISD FT CMDHQRKVALDNLLSRSLLALLGLAVIAFAFGYAMAGRVLSPLGRITRTARAVAGSDLS FT RRIELDGPDDELKELADTFDDMLERLQRAFTAQQRFVGNASHELRTPLAINRTLLEVHL FT SDPGAPVELQQLGKTLLATNERSELLVEGLLLLARSDNQIVERKPVDLAEVAGQAIDQV FT HAEAESKGVEVRGTREAAVVQGNGVLLERIALNLVQNAVRYNVAGQGWVEVATAVENGQ FT AVLVVTNTGPVVPAYEVDNLFEPFRRLRTERTGSDKGVGLGLSIARSVARAHGGHISAQ FT PREGGGLVMRVTLPV" XX SQ Sequence 2815 BP; 462 A; 1029 C; 914 G; 410 T; 0 other; ctgcagaagt cctgcggtga aagcgtccat gctgcgcccc ctcgtcctgg gtcgtgggtc 60 gttggcacgg tggtgtgccg atcggaaggg gcgatcacgc ctccggtgga gtgcccagcg 120 ctgccctgcc gggcggcgac cgtgccggac acccacgccc gctctgcgga agcggaccgc 180 ggcgtaccgc gcggtaacgc ggtacaggca gagcgtgatc gcggggtgta aagccgtcct 240 cccccagctc cccttcgcgg aaacctcaac cacacgagaa aatctcgcat tcccgctcac 300 gaggcctttc cgcgccctgc ttcggcaccg gctcctcacc cggcttacag ccgacttatg 360 gccgaaaagg gcaggatgga ggcaacacac ccaccaggcc cctgccctcg tgcgtccgag 420 aagcgctacg cgggtggaca caggaaggac aagcgacgtg cgcgtactcg tcgtcgagga 480 cgagcagctg ctcgccgatg cggtggccac cggactgcgc cgggaggcca tggccgtcga 540 cgtcgtgtac gacggcgcgg ccgccctgga gcgcatcggc gtcaacgact acgacgtggt 600 cgtcctcgac cgcgacctcc ccctcgtgca cggcgacgac gtctgccgca agatcgtcga 660 actgggcatg cccacgcgcg tgctcatgct cacggcctcc ggcgacgtca gcgaccgggt 720 cgagggcctg gagatcggcg ccgacgacta cctgcccaag cccttcgcgt tcagcgagct 780 gatcgcccgc gtgcgcgccc tgggccggcg caccagcgtg ccgctgccgc cggttctgga 840 gcgggccggg atcaagctcg accccaaccg ccgggaggtc ttccgggacg gcaaggaggt 900 gcagctcgca cccaaggagt tcgccgtcct ggaggtcctc atgcgcagcg agggcgccgt 960 ggtctccgcg gagcagctcc tggagaaggc ctgggacgag aacaccgacc ccttcaccaa 1020 cgtcgtgcgc gtgaccgtca tgaccctgcg ccgcaagctg ggcgagccgc ccgtcatcgt 1080 caccgtcccc ggctccggct accggatctg accggccgtg gcgacgacac ccgcgccccc 1140 cggggcgccc cccaagccca cgtgggaccc gcgctcggcc acgcccctgc cgtggctgcg 1200 ccccaccatc cggataaggc tcacgctgct gtacggcggc atgttcctga tcgccggcat 1260 cctgctgctg tcgatcatct acctgctcgc cgcccaggcg gtgcgcaccg gcaacgaacc 1320 gctgtacaag atcgtcgact tcaccgacct caaggtctcc agcagcacct gtcccgtggt 1380 cgacaacggc ggcctgtcgc tgtccgactt caacgccgcc atcagcgact gcatggacca 1440 ccagcgcaag gtcgccctgg acaacctgct cagccgctcc ctgctggcgc tcctcggcct 1500 cgccgtgatc gccttcgcct tcggctacgc catggccggg cgcgtcctgt ccccgctggg 1560 gcggatcacc cgcaccgcgc gcgcggtggc cggctccgac ctctcccgcc gcatcgagct 1620 ggacggcccg gacgacgagc tgaaggagct ggccgacacc ttcgacgaca tgctggagcg 1680 gctgcagcgg gccttcaccg cccagcagcg cttcgtcggc aacgcctccc acgagctgcg 1740 cacgccgctg gcgatcaacc gcacgctcct ggaggtgcac ctgtccgacc cgggtgcccc 1800 ggtggagctc cagcagctcg gcaagacgct gctcgccacc aacgaacgca gcgagctgct 1860 ggtcgagggc ctgctcctgc tggcccgcag cgacaaccag atcgtcgagc gcaaaccggt 1920 ggatctcgcc gaggtggccg gccaggccat cgaccaggtg cacgccgagg ccgagagcaa 1980 gggcgtggag gtccgcggca cccgcgaggc cgcggtggtc cagggcaacg gcgtcctgct 2040 ggagcggatc gccctgaacc tcgtccagaa cgccgtgcgc tacaacgtgg ccggacaggg 2100 ctgggtagag gtcgccaccg ccgtcgagaa cggccaggcg gtcctggtgg tcaccaacac 2160 cggccccgtc gtaccggcgt acgaggtgga caacctcttc gagccgttcc ggcggctgcg 2220 caccgagcgg acgggcagcg acaagggcgt gggcctcgga ctgtccatcg cgcggtccgt 2280 ggcccgggcg cacggcggcc acatctccgc ccagccgcgc gagggcggag ggctcgtgat 2340 gcgcgtgacg ctccccgtct gagatcatga ccccgacatc tcaccgagac ccgaggatgt 2400 tcgctttgag cggaatttcc aggccaccgg ccctggagtc gcctgtgtga tcgatcacag 2460 cggaggcttt cccgccctcc actctccgtg atcatgcacc ctgtcggaaa gccgggaaaa 2520 tcccggtttt cagggcccct gatcacggga agtacacggt gagacgcctt tgaagtgcgg 2580 cattcggacc gtgtacggtc cccatcgcca tccaagccga tcactcgtga ggagtccggt 2640 tgggtgtcga ttgagtaaca gaccttgatg tgaggcaaaa tctccgcctc aggtcgggca 2700 caagtccggc ctctcacgcg ttacgtgcgc tgaagacacc gcagacaccc agagggggag 2760 agcgaccatg gcaaccgatt acgacactcc acgcaagacc gacgacgacg tcgac 2815 // |
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