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EBI DbfetchID X58774; SV 1; linear; genomic DNA; STD; VRL; 4898 BP. XX AC X58774; XX DT 14-JUN-1991 (Rel. 28, Created) DT 15-NOV-2007 (Rel. 93, Last updated, Version 7) XX DE Herpesvirus saimiri sRNA1, sRNA2, sRNA3 and sRNA4 genes for small viral DE RNAs XX KW dihydrofolate reductase; small RNA; sRNA1 gene; sRNA2 gene; sRNA3 gene; KW sRNA4 gene. XX OS Saimiriine herpesvirus 2 (Herpesvirus saimiri) OC Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae; OC Gammaherpesvirinae; Rhadinovirus. XX RN [1] RP 1-4898 RA Medveczky P.G.; RT ; RL Submitted (14-MAR-1991) to the EMBL/GenBank/DDBJ databases. RL P.G. Medveczky, Univ of South Florida, Dept of Medical Microbiology and RL Immunology, 12901 Bruce B. Downs Blvd, Tampa FL 33612-4799, USA XX RN [2] RX DOI; 10.1007/BF01703599 RX PUBMED; 8209420. RA Geck P., Whitaker S.A., Medveczky M.M., Last T.J., Medveczky P.G.; RT "Small RNA expression from the oncogenic region of a highly oncogenic RT strain of herpesvirus saimiri"; RL Virus Genes 8(1):25-34(1994). XX CC highly oncogenic strain of Herpesvirus saimiri; sRNA1 and sRNA2 CC located in cytoplasm, sRNA3 and sRNA4 located in nucleus; small CC RNAs show significant similarities to cellular uRNAs XX FH Key Location/Qualifiers FH FT source 1..4898 FT /organism="Saimiriine herpesvirus 2" FT /map="right end 4.5% of L-DNA" FT /strain="484-77" FT /mol_type="genomic DNA" FT /db_xref="taxon:10381" FT ncRNA 3921..4039 FT /note="small RNA 1 - encoded by viral sequence and appears FT in cytoplasm" FT /ncRNA_class="scRNA" FT ncRNA 3463..3572 FT /note="small RNA 2 - encoded by viral sequence and appears FT in cytoplasm" FT /ncRNA_class="scRNA" FT ncRNA 872..952 FT /note="small RNA 3 - encoded by viral sequence and appears FT in nucleus" FT /ncRNA_class="snRNA" FT ncRNA 1751..1814 FT /note="small RNA 4 - encoded by viral sequence and appears FT in nucleus" FT /ncRNA_class="snRNA" FT CDS 1881..2441 FT /note="ORF - has homology to dihydrofolate reductase" FT /db_xref="GOA:P27421" FT /db_xref="HSSP:1KMS" FT /db_xref="InterPro:IPR017925" FT /db_xref="UniProtKB/Swiss-Prot:P27421" FT /protein_id="CAA41575.1" FT /translation="MVLLLNCIVAVDQNMGIGKNGYLPWPLLTNDFKYFQRMTTSSVKN FT KQNLVIMGKNTWFSIPEKNRPLKDRINLVLSKKLKEIPHGAHFLARSLNDALKLIEQPE FT FVNKVDMVWIIGGSSVYKDAMNYSSHLKLFVTRIMQSFETDTFFPEIDLKKYKPLIEYP FT GVPSNTQEEKGIRYKFEVYEKNY" XX SQ Sequence 4898 BP; 1831 A; 722 C; 786 G; 1559 T; 0 other; ctgcagactc agcatctagc atgtctagtt ctagtctttt atcttgtgga ataacaaaat 60 tttttaaacc agtataaggc ttgcatagca ttttttgaag atgtcgaatg tgcctttttt 120 tagggtcttt aaggtcgcaa attatgtgta tagtcctata atattcaatt ctttcaactg 180 taaatgcatt ttcaggacct tgcggggtaa acatagacaa gttcttaact acatctacta 240 gatcttttga aaatgttgtc tgggaacctt gaagatgagg accataagaa aatgacaaag 300 tttgttcaga aaccctagaa aaaggtagct tcagtgaaac actaagaaac agtttactaa 360 gaacaggctc aagaaatgac gtattagggg aatttacgta aaccacatat ccggtggtcg 420 tggttggatt gtgagacgta acttgtaatg ggccattctc taaaaaaacc gaagttgcta 480 atcttttcct gtggaagaat ttgagtttca taagagtcaa agtgtaagac aagcatgttt 540 ctgccacaaa agttttgttc agcaattgac tttaataatt aaacaatagt ttttaaatgc 600 agctacaaga agcaattttt gtatttgatt aaaacgccac cggaaaagga cgcgattctt 660 aaatgaaagt tataaagtaa tttgaatatt tgttaaacgt gttgtaaaaa atatgtattg 720 ttttagtaaa ataatagcac aaaagtttgc atcaatgttt ttatataaaa aagtaaagca 780 aactgttttt atttaaaaat taaagtacaa caccataact gataaagatg tcagcatcag 840 gctatagcta aactcattgc aaatcagctt tatatccaca aaatgctttg ataattccga 900 ttaatttttg gaggcactag gtacttaggc aaatttaggg aaactagtgc caaccttcaa 960 gttaaaaaca gaattgtcta tttaaaaagt ttctgagtta acaaaactaa ctacaaaaga 1020 gcttgagaca aaatgaaaat tatcaagtaa tttaaaaata gccttttgca aaaatattat 1080 gaacttttaa aagcttgtaa gtacctatag agttacatca aaaagcaaaa acttcaaaag 1140 aaacacattg tgttaatgag aaataatata cacaaaataa aaacttactg taactaaaaa 1200 aagttagtgc taactaagac atacagaaag cagtaacacg atagcaccag ttacacataa 1260 gcattcagat aatttttaga agtattggga atataagtat aaactagtgc tactgctatt 1320 agtttaaaag cagaagatgt gctatgctat tactgtgcta atcttaacaa agtgaaagta 1380 aaaacttgtt tctaacaaga gtttagcaat tagatttaaa acttataaac agcctacaaa 1440 gtaaaagtta ttcatatgct aagtagatat tacactacat actttgcaat gtcttacaat 1500 tctaacttta aatgaacagg aaaaggaagt ctctcttaag atgaaagttc taaagtgatc 1560 tgaatatccc ttaaacacgt actaaaaata cttactgctt atttaatgaa tagtagtaaa 1620 ttagttcaca caaactgttg ttttattgtg taacagtgac tgttacacaa taaaacaaca 1680 gattataaaa ataccataac tagtaataag attatttttt cttaaacttc acaaatcacc 1740 tttcagctac agtggctaac agtttcaaat tcagtaaatt tttggaggct ctggggtagt 1800 ccaaaccagt gccaaatttg caagtaaaaa aagacagttt ttataacctt gtaagaccaa 1860 ctttttgttt acaataacta atggttctct tgctaaactg tattgttgct gtagaccaga 1920 atatgggcat aggcaaaaat ggctacttgc cttggccctt gcttacaaat gactttaagt 1980 attttcagag aatgactact tcctctgtaa aaaataaaca gaatttagta attatgggta 2040 agaatacctg gttctcaatt cctgaaaaaa atcgacctct aaaagacaga attaatttag 2100 ttctcagtaa aaaacttaaa gaaattcccc atggagctca ctttctagct agaagtttaa 2160 atgatgcctt aaaacttatt gaacaaccag aatttgtaaa taaagtagac atggtatgga 2220 taattggagg cagttctgtt tataaagacg ctatgaatta ttcaagccat cttaaactgt 2280 ttgtgacaag aattatgcaa agctttgaaa cagacacttt tttcccagaa attgatttaa 2340 agaaatataa acctttaata gaatacccag gagttccttc taacacacaa gaagaaaaag 2400 ggattaggta caaatttgaa gtatatgaaa aaaattatta atacttttct atttaaaagt 2460 catgcaggac tcacttgctc aatgaagctt aaagaagttg gttatgattt tgagctctcc 2520 cagctaaaaa atttaaacct gcttaaagtt gtgacaaaaa ttaaaattta gaaaaattaa 2580 caaaagtcat gcaacgttaa cagtgtttta cattttttgt tataagtttt aacaattaaa 2640 tgctggtgca atgttacgtt tttgaatatt ttgtttcaat aaaaagtttt aacttttgtt 2700 ttgtgtcact gagtgtacta agtagtctaa ttgtaaaaac taaaatcaaa cattattttt 2760 ctccaaagag acttaattag aaatgatgtc aaagtagagt gctacatccc tatgtgtgct 2820 ccctgtgctg taactgaaaa gcatatactc tcctcctttt aatttcttcc tatattttta 2880 gaagcagtaa gtgttactta ataacagcca cttttagcaa gaagttacag cagtgagggt 2940 aatactatat aattgagatc ataaactttt gataagtaat tccaagttaa taaaagcttt 3000 cattttaaga gactgtcttg ttaaaagata caaagatggc gacagtcagt gcttctcgtc 3060 taaatatctt ttccttaaaa ccttaactta agcatataac taaaatctta gctagattgc 3120 tacaaataat aagtgtttta gatttttagt tgcttacaat tagctcagtt agtagtatat 3180 agctacaacg ttaatgttgt attctagaat tgaaggcata aaaaagtaca ggaagtatgc 3240 taaaagtgaa acttgaacaa taatttgaat attactcaga ctattaggtg tctaaaaaac 3300 agtcatgtct agcgtaacta aaatttttag agcaaaatgt cataaccttt ggcgtaggcg 3360 gttcttttga aattaaaagt taaaaatgtc aagtttaaat ttctagtcat aactttagaa 3420 ggtgttagat ttagctaaga gtagcaaagt aaagacagct gtactctaca tatttattgt 3480 atttattaat gctgctttaa acctcacaca caaggatttg cttctactaa tttttgaaag 3540 cactgggtgt acatagttga aaaccagtgc tacttaagtt aaaaaaaaga tatactgtgc 3600 tctcactact ataaactttg ctgtttttag tatatagtgt tgagagcact ccataacaag 3660 tcaaactcaa cgtatgaatt aaactacatt taaaagttaa gttgtaagtg aaagcggtac 3720 aaaaaatttg catatgaaaa aaaattgtta gaaataatgc ttgctacatt gcatgtacaa 3780 aataaaagca cagagtctcc actttaacat gtagtcatgt attgcataaa ttgtacacaa 3840 caataaactt taaaaaaact aaccataact gaaacattag ttgtttttac caagaaacag 3900 caaatacagc catttttagt acactacata tttatttaca tgtttactat aacttaactt 3960 gtgactaacc ttacttgctg taccatccaa aagctaattt ttgcaggtgc tgggtgtaaa 4020 tatagagtaa ccagcaccat ttaaagtagt taaaagtaaa ctttatttgt aacttctata 4080 agtgatcatg acaagtaaga aacaaagtta atgaatagca gctgtgctcg tacctagcat 4140 gttactgctc tctcacttcc atgctttgat gttgctgcat tcactagaca taagatattt 4200 tctttatcag caaagaaact ccaccactgc tagcttgcat aaaaagtaga aaatctcgaa 4260 ttaacactga gggaaagaga tgcgagaaca aggtgacaaa tatctccata gctttgcttt 4320 cagcactagc tagggttaaa ttaacaatta gcttcttttt ttgcatgttt atttcttctc 4380 tcttttcact tattcatcta agtaacatga actaaagcgg attgtttata agtagctgaa 4440 atcttttaga atgtaattct attttaagaa tactgttaat gctttatgta gtatagataa 4500 cagaaaaata tcctaaaaag tatagcattg cagaaagaag agtttacaaa ccagacattt 4560 agattagaat gctagatttg ttacttatat gttctaaaaa cagtgctaga gaaaatatat 4620 tttgagagtt tagcagggta ttatgaagta agagtgggta gagaaatgtg tcagacaaga 4680 agtaggcaat gtgggaagag cagaattaac ctctggtttc taaaagtcaa aatctgaata 4740 gttaaaattt gaatttgaaa ttatctataa atgtggtaag ttgtaaaaca ccagatgaag 4800 ggtcacagga gtttccaaaa tgtagtaagc taacatataa atatcagcag aaaatagagt 4860 aacacaagaa acagctaaca agagcaacac aaacacgc 4898 // |
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