 |
|
EBI DbfetchID X56660; SV 1; linear; genomic DNA; STD; PRO; 6358 BP. XX AC X56660; XX DT 10-APR-1995 (Rel. 43, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 8) XX DE L.lactamgenus YK90 DNA for cephalosporin biosynthesis genes XX KW cephalosporin. XX OS Lysobacter lactamgenus OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; OC Xanthomonadaceae; Lysobacter. XX RN [5] RP 1-6358 RX DOI; 10.1007/s002530050604 RX PUBMED; 8703429. RA Kimura H., Izawa M., Sumino Y.; RT "Molecular analysis of the gene cluster involved in cephalosporin RT biosynthesis from Lysobacter lactamgenus YK90"; RL Appl. Microbiol. Biotechnol. 44(5):589-596(1996). XX RN [6] RP 1-6358 RA Kimura H.; RT ; RL Submitted (29-OCT-1990) to the EMBL/GenBank/DDBJ databases. RL H. Kimura, FERMENTATION CENTRE, TECHNOLOGY DEVELOPMENT LABORATORIES, TAKEDA RL CHEMICAL INDUSTRIES LTD, JUSOHONMACHI, YODOGAWA-KU, OSAKA 532, JAPAN XX FH Key Location/Qualifiers FH FT source 1..6358 FT /organism="Lysobacter lactamgenus" FT /strain="YK90" FT /mol_type="genomic DNA" FT /db_xref="taxon:39596" FT CDS 232..1212 FT /transl_table=11 FT /product="isopenicillin N synthase" FT /db_xref="GOA:Q48739" FT /db_xref="InterPro:IPR002057" FT /db_xref="InterPro:IPR002283" FT /db_xref="InterPro:IPR005123" FT /db_xref="UniProtKB/Swiss-Prot:Q48739" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA39983.1" FT /translation="MNRHADVPVIDISGLSGNDMDVKKDIAARIDRACRGSGFFYAANH FT GVDLAALQKFTTDWHMAMSPEEKWELAIRAYNPANPRNRNGYYMAVEGKKANESFCYLN FT PSFDADHATIKAGLPSHEVNIWPDEARHPGMRRFYEAYFSDVFDVAAVILRGFAIALGR FT EESFFERHFSMDDTLSAVSLIRYPFLENYPPLKLGPDGEKLSFEHHQDVSLITVLYQTA FT IPNLQVETAEGYLDIPVSDEHFLVNCGTYMAHITNGYYPAPVHRVKYINAERLSIPFFA FT NLSHASAIDPFAPPPYAPARGNPTVSYGDYLQHGLLDLIRANGQT" FT CDS 1273..2232 FT /transl_table=11 FT /product="deacetylcephalosporin C synthetase" FT /db_xref="GOA:Q48740" FT /db_xref="HSSP:1RXF" FT /db_xref="InterPro:IPR005123" FT /db_xref="UniProtKB/TrEMBL:Q48740" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA39984.1" FT /translation="MTDSGIQIFDLDELEHGVRLDSFRKSLFERGVFYVREDDSIKTEH FT AKAMDAVMDLFENGSAEQKNALRNLTPNVRRGFSDLEAESTARITKGGEYTDYSMVYSI FT GLTDNLFPSPAFEAIWTGYFDRFYARTQDIARSVLRASDAGLDESVDEFLDCDPLLRFR FT FFPEVPEDRCAEQEPRRMAPHYDLSIITTIQQTPCANGFVSLQVDVDGRYVDLPPVPGC FT MVVFCGAVAPLVSGGRIKAPRHQVASPSMQQRVGSSRTSSVFFLRPKPDFRFSVPLARA FT SGLDVDFTGDTATFGEWIGGNYVNLRSANAPSRAAERV" FT CDS 2269..3210 FT /transl_table=11 FT /product="deacetylcephalosporin C synthetase" FT /db_xref="GOA:Q48741" FT /db_xref="HSSP:1E5I" FT /db_xref="InterPro:IPR005123" FT /db_xref="UniProtKB/TrEMBL:Q48741" FT /protein_id="CAA39985.1" FT /translation="MNDRTVPTFALEQLQRGEHKDALRRCAMEKGAFYLQIDGPLSAAH FT DRAGKAAMDFFATADDAAKQAVINANPNTRRGFSPLGSESTARCTNTGDYSDYAMVYSM FT GISGNIFPTAHFERLWSDYFDLYYGISRQAARAVLESMDVHLNTDIDALIDCDPVLRYR FT YFPDVPEDRCAEQQPNRMAPHYDLSIVSLILQTPCPNGFVSLQVEIDGRFVEVPPRPGC FT VVVFCGSIAPLVSDGKIKAPQHRVVSPGAAQRIGSNRTSSVLFLRPKSEFSFSVPLAKA FT LGMGDDLVGERATFGEWCGANYMEMHVTTAPS" FT CDS 3273..4532 FT /transl_table=11 FT /product="isopenicillin N epimerase" FT /db_xref="GOA:Q48742" FT /db_xref="InterPro:IPR000192" FT /db_xref="InterPro:IPR015421" FT /db_xref="InterPro:IPR015424" FT /db_xref="UniProtKB/TrEMBL:Q48742" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA39986.1" FT /translation="MTSPADPNGARDRMLLPPSVVYLNAGSFGPLPRSVFEAAAGFRRR FT LAEEPTDFLLREAPALLWRAREQLAGFVGCAPHRLLFTASVSAAVALVAASLRLNAPGE FT ILLSDQEYLTMRWCWDRVAERSGLSLRTFAIPQRASDPEEIVQAAVGAMGPATRLLFFS FT HIVSATGLILPARRLCEEAQGRGIVSVVDGAHAVASIALELAEIPCDFYVGSCHKWLLA FT PSGASFLYLGREREERLQPLTISWGHRSAQAESAPDERDPFGSTPRLRRLECEGTRDIC FT PWFAVPEAIGFQRSFGADAGFAHRRALAGYARERFAESLGWAVATPPDPALGSAMTAFA FT VPAQAEPERLQRTLWERFRIEAAVVDRLGQPLLRLAPHVYNSRSDIDVLVESLRALMPP FT SPRPRPTADAAAAGTQRQPG" FT CDS 4657..5814 FT /transl_table=11 FT /product="beta-lactamase" FT /db_xref="GOA:Q48743" FT /db_xref="InterPro:IPR001466" FT /db_xref="InterPro:IPR001586" FT /db_xref="InterPro:IPR012338" FT /db_xref="UniProtKB/Swiss-Prot:Q48743" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="CAA39987.1" FT /translation="MKRLLAFCLLFFAALGQAKVPPPARSAADAEIQRAVAAFMQQYQV FT PGVAVGITVDGAERYYNYGVSSRKTQAKVGANTLFEVGSVSKTFTATLASYAQVNQQLS FT LADHPGKYLPEMKGHDFDKVTLLNLGTHTAGGFPMQVPTQVKTDQQLTAYFQSWHPQYP FT AGTKRTYANPGIGMLGVIAAKSMRMPFQKAMTGVLLPKLGLTNTYLTVPPAKMAFYAQG FT YDDKGQPVRMSPGALWEPTYGIKTTARDLLRFVEINLDQVKVEPKLKRAIDGTHVGYYR FT LGEMTQGLVWEQLPYPASETSLQANSSQKVIFESNAVAALTPPRPPQANVLINKTGSTR FT GFGAYVAFNPARKIGIVLLMNRSVPMDGRIKLAHTILDTAGGMAK" XX SQ Sequence 6358 BP; 1089 A; 2233 C; 2001 G; 1035 T; 0 other; gagctcgccg ttcaacaatc tcgacacgct gctgccgcca tcggcgttca cgctggagat 60 cctcggcgac aacagccact tctcgtggat ccacgagaag acgacggtgg acaaggtgtg 120 ctcgacgacc gcctccctgg tccgcgaacg aatgaccacc taggcgccgg acgcaatgat 180 cggagttcgt ttcaagcatc gactactttc cttacaggag cagagctgat catgaacaga 240 catgccgacg tgcccgtcat cgatatttcc ggattgtccg gaaacgacat ggacgtcaag 300 aaggacatcg ccgcccggat cgaccgcgcc tgccgcggct cgggcttttt ctacgccgcc 360 aaccacggcg tcgatctggc ggcgctgcag aaattcacca ccgactggca tatggccatg 420 tcgcccgagg agaagtggga gctggcgatc cgcgcctaca acccggccaa tccgcgcaac 480 cgcaacggct actacatggc ggtcgagggc aagaaggcca acgagtcgtt ctgctacctc 540 aatccctcgt tcgacgcgga ccacgcgacg atcaaggccg ggctgccctc gcacgaggtc 600 aacatctggc cggacgaggc ccgccatccg ggcatgcgcc ggttctacga ggcgtatttt 660 tcggacgtgt tcgacgtcgc cgcggtcatc ctgcgcggct tcgcgatcgc gctggggcgc 720 gaggaatcgt tcttcgagcg gcacttcagc atggacgaca ccctgtcggc ggtgtcgctg 780 atccgctacc cgttcctgga gaactatccg ccgctgaagc tcggcccgga cggcgagaag 840 ctcagcttcg agcatcacca ggacgtatcg ctgatcaccg tcctgtacca gaccgcgatc 900 cccaacctgc aggtcgaaac cgccgagggt tatctcgaca tcccggtttc cgacgagcat 960 ttcctggtca actgcgggac ctacatggcc cacatcacca acggctacta cccggcgccg 1020 gtgcatcggg tcaaatacat caacgccgag cggctgtcga ttccgttctt cgccaatctc 1080 tcgcacgcca gcgccatcga tccgttcgcg ccgccgccgt acgcgccggc gcgcggcaac 1140 ccgaccgtgt cgtacgggga ctatctgcag cacggattgc tggatctgat ccgcgccaac 1200 gggcagacct gagccgagcg gcccgccgca cccgatcctt accgaagttc cgatagccaa 1260 ggtgatgcag aaatgaccga ttcaggcatc cagatattcg acctggacga actcgagcac 1320 ggcgtccggc tcgattcgtt ccgcaaatcc ctgttcgagc gcggcgtgtt ctacgtgcgc 1380 gaggacgatt cgatcaaaac cgagcacgcc aaggcgatgg acgccgtcat ggacctgttc 1440 gagaacggca gcgcggaaca gaagaacgcg ctcaggaacc tgaccccgaa cgtgcggcgc 1500 gggttttccg acctggaggc cgagagcacg gcgcggatca ccaagggcgg cgaatacacc 1560 gactactcga tggtctattc gatcggcctg acggacaacc tgttcccgtc gccggcgttc 1620 gaagccatct ggaccggcta tttcgaccgt ttctacgctc gcacccagga catcgcgcgt 1680 tcggtgctgc gcgcgtccga cgccgggctc gacgagagcg tggacgagtt cctcgactgc 1740 gatccgctgc tgcgtttccg ctttttcccg gaagtgccgg aagaccgctg cgccgagcag 1800 gagccgcgcc gcatggcgcc gcattacgac ctgtccatca tcaccaccat ccagcagaca 1860 ccctgcgcca acggcttcgt cagcctgcag gtcgacgtcg acggccgtta cgtcgatctg 1920 ccgccggtgc cgggctgcat ggtggtgttc tgcggcgcgg tcgcgccgct ggtttcgggc 1980 ggcaggatca aggcgccgcg ccaccaggtc gcctcgccgt cgatgcagca gcgcgtcggc 2040 agcagccgca cctccagcgt gttcttcctg cggccgaagc cggacttccg gttctcggtg 2100 ccgctggccc gggccagcgg actcgatgtc gatttcaccg gcgacaccgc caccttcggc 2160 gagtggatcg gcggcaacta cgtcaacctg cgctccgcca acgccccgtc gcgggccgcg 2220 gaacgggtgt gatccagcca gcgccatgcc tacaagggac tcaagcgaat gaacgaccgg 2280 accgtgccca ctttcgcatt ggaacagctc cagcgcggcg agcataagga cgcgctgcgc 2340 cgatgcgcga tggaaaaagg cgcgttctat ctccagatag acgggccgct gagcgccgcg 2400 cacgatcgcg cgggcaaggc cgccatggac ttcttcgcga ccgccgacga tgcggcgaag 2460 caggccgtca tcaacgccaa cccgaacacc cgccgcggat tctcgccgct gggctcggaa 2520 agcaccgcgc gctgcaccaa caccggcgac tactcggact acgccatggt ctactccatg 2580 ggcatctcgg gaaacatctt cccgaccgcg catttcgagc ggctgtggag cgactacttc 2640 gacctgtact acggcatctc ccggcaggcc gcgcgcgcgg tgctggagag catggacgtc 2700 catctgaaca ccgacatcga cgccttgatc gattgcgatc cggtgctgcg ctaccgctat 2760 tttcccgacg tgcccgaaga ccgctgcgcc gagcagcagc ccaaccggat ggcgccgcac 2820 tacgatctgt cgatcgtgtc gctgatcctg cagacgccgt gtcccaacgg cttcgtcagc 2880 ctgcaggtgg agatcgacgg gcgcttcgtc gaagtgccgc cgcggccggg ttgcgtggtg 2940 gtgttctgcg gatcgatcgc gccgctggtg tccgacggca agatcaaggc accgcagcac 3000 cgcgtggtct cgcccggcgc ggcgcaacgc atcggcagca accgcacctc gagcgtgctg 3060 ttcctgcggc ccaagtcgga gttcagcttt tccgtcccgc tggccaaagc gctcggcatg 3120 ggcgacgatc tggtcggcga gcgggccacg ttcggcgaat ggtgcggcgc caactacatg 3180 gagatgcacg tcaccacggc gccttcctga gcccggcccg gggcgccgca gccgccttcc 3240 gcaaccgccg caccgctgga gctttcttgt cgatgacgtc ccctgccgac ccgaacggcg 3300 cccgcgaccg catgttgctg ccgccgtcgg tggtgtatct gaacgccggc tcgttcggcc 3360 ccttgccgcg cagcgtgttc gaagcggcgg ccgggtttcg gcgccggctc gccgaggagc 3420 cgacggattt cctgctgcgc gaggcgcccg ccctgctgtg gcgcgcgcgc gaacagctgg 3480 ccggcttcgt cggctgcgcg ccgcatcggt tgctgttcac cgccagcgtc agcgcggcgg 3540 tggccctggt ggccgcgtcg ttgcgcctga acgctcccgg cgagatcctg ctcagcgacc 3600 aggaatacct gaccatgcgc tggtgctggg accgggtcgc ggagcgctcc ggcctgagcc 3660 tgcgcacgtt cgcgattccg cagcgggctt cggacccgga agagatcgtg caggcggccg 3720 tcggcgccat ggggccggcg acccggctgc tgttcttcag ccatatcgtc tcggcgaccg 3780 gactgatcct gccggcgcgc cgcctgtgcg aggaagcgca aggccgcggc atcgtcagcg 3840 tcgtcgacgg cgcccacgcg gtggcgtcga tcgcgctgga actggccgag attccctgcg 3900 acttctatgt cggcagctgc cataaatggc tgctcgcgcc gagcggcgcg agttttctct 3960 acctcggccg cgagcgcgaa gaacgcctgc agccgctgac gatcagttgg gggcatcgca 4020 gcgcccaggc cgaatcggcg ccggacgagc gcgacccgtt cggcagcacg ccgcgcctgc 4080 gccggctgga gtgcgagggc acccgcgaca tctgcccctg gttcgcggtg ccggaagcga 4140 tcgggttcca gcgctcgttc ggagccgacg cgggcttcgc gcaccggcgc gcgctcgccg 4200 gctatgcgcg cgagcgcttc gccgaaagcc tcggctgggc cgtggcgacg ccgcccgatc 4260 ccgcgctggg cagcgcgatg accgccttcg ccgtgccggc ccaggccgag cccgagcgct 4320 tgcaacgcac gctgtgggag cgcttccgca tcgaagccgc cgtggtcgac cggctcggcc 4380 agccgctgct gcggctcgcg ccccacgtct acaactcgcg ttcggacatc gacgtcctgg 4440 tcgagagcct gcgcgcgctg atgccgccgt cgccgcgccc gcgtccgacc gcggacgccg 4500 cagcggccgg gacgcagcgc cagcccgggt gaaccgccgc catcggcgcc tttgccgagt 4560 ttgccgaagg cggggccggt gcgatgatgg cgcgctcatc cgggcgaaca tggtccgcac 4620 cggccccggc cgccgccccg aacaaggaca cgcgtaatga aaaggctctt ggccttctgt 4680 ctgcttttct tcgccgccct cggccaggcc aaagtacccc cgcccgcacg cagcgccgcc 4740 gacgcggaaa tccagcgcgc ggtcgcggcc ttcatgcagc agtaccaggt gcccggcgtc 4800 gccgtcggca tcaccgtcga cggggccgag cgctactaca actacggcgt gagctcgcgc 4860 aagacccagg ccaaggtcgg cgccaacacg ctgttcgaag tcggctcggt cagcaagacc 4920 ttcaccgcca ccctcgccag ctacgcgcag gtcaaccagc aactgtcgct ggccgatcac 4980 cccggcaagt acctgccgga gatgaaaggc cacgacttcg acaaggtcac gctgctgaac 5040 ctcggcacgc acaccgccgg cggctttccg atgcaggtgc cgacgcaggt caagaccgat 5100 caacagctga ccgcctattt ccagtcctgg cacccgcaat accccgccgg caccaagcgg 5160 acctacgcca atccgggcat cggtatgctc ggcgtgatcg ccgccaaaag catgcgcatg 5220 ccgttccaga aggccatgac cggcgtgttg ctgccgaagc tggggctgac caacacctac 5280 ctcaccgtcc cgcccgccaa gatggcgttc tacgcccagg gctacgacga caagggccag 5340 cccgtgcgca tgagcccggg cgcgctgtgg gagccgacct acggcatcaa gaccaccgcc 5400 cgggatttgc tgcgcttcgt cgagatcaac ctcgatcagg tcaaggtcga gcccaagctc 5460 aagcgcgcca tcgacggcac ccatgtcggc tattaccggc tcggcgaaat gacccagggc 5520 ctggtctggg agcaactgcc ctatcccgcc agcgagacca gcctgcaggc gaacagctcg 5580 cagaaagtca tcttcgaaag caacgccgtc gccgcgctga cgccgccgcg gccgccgcag 5640 gccaacgtgc tgatcaacaa gaccggatcg acccgcggat tcggcgccta cgtcgcgttc 5700 aaccccgcgc gcaagatcgg catcgtgctg ctgatgaacc gcagcgtgcc gatggacggc 5760 aggatcaagc tcgcgcatac gattctggat acggcgggcg gaatggcgaa gtagcggtcg 5820 ttcaaggttc gggttgtcgg cgcgacatgc cgcagcgggc gtatggcctg ctcagaagat 5880 cgccgatggt gttgtcggcc gcgcgaggcg acggcccgag actgcgcagg acagatccag 5940 tcgccagggc aacaaaaagg gctccgaaga gccctttttt gttgccttgc ttctggattc 6000 gaacgtcgct tgcctcttag cgcgccttct tggccgcagc tttcaggtcg atcatgcagc 6060 gatttgcgga ggaacacagt gcatggcggc cccacaccca gcgaaaccca ctcccgctac 6120 cgccccctca cccacacttc gaatacccgc aattcaaaca cgtcgcacag ccatccatga 6180 tcaccaaggc cttggtgctg cacttgtgac acatggtcgc gctgggcggg aagctggtgc 6240 cgtcgccggt aacggtcacg tcttcgctgc gcggcgcgac cacggtcagc ggggcgccgg 6300 cgtcagagtt tttttttgag cgctcttcgt aagcgcgacg cttctcggcg atgagctc 6358 // |
|