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EBI DbfetchID X55394; SV 3; linear; genomic DNA; STD; PRO; 10144 BP. XX AC X55394; XX DT 29-MAY-1991 (Rel. 28, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 5) XX DE Methylosinus trichosporium gene cluster for methane monooxygenase (MMO) DE with mmoR, mmoG, mmoX, mmoY, mmoB, mmoZ mmoD and mmoC genes XX KW GroEL protein; methane monooxygenase; mmoB gene; mmoC gene; mmoD gene; KW mmoG gene; mmoR gene; mmoX gene; mmoY gene; mmoZ gene; KW sigma 54 dependent transcriptional regulator MmoR; sMMO. XX OS Methylosinus trichosporium OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; OC Methylocystaceae; Methylosinus. XX RN [1] RC Revised by [3] RA Cardy D.L.N.; RT ; RL Submitted (23-OCT-1990) to the EMBL/GenBank/DDBJ databases. RL Cardy D.L.N., University of Warwick, Biological Sciences Dept., Coventry RL CV4 7AL, UK. XX RN [2] RP 1-4440 RX DOI; 10.1111/j.1365-2958.1991.tb02114.x RX PUBMED; 1904125. RA Cardy D.L.N., Laidler V., Salmond G.P.C., Murrell J.C.; RT "Molecular analysis of the methane monooxygenase (MMO) gene cluster of RT Methylosinus trichosporium OB3b"; RL Mol. Microbiol. 5(2):335-342(1991). XX RN [3] RC revised by [4] RA McDonald I.; RT ; RL Submitted (02-JUN-1999) to the EMBL/GenBank/DDBJ databases. RL McDonald I., University of Warwick, Biological Sciences Dept., Coventry CV4 RL 7AL, UK. XX RN [4] RP 1-10144 RA McDonald I.; RT ; RL Submitted (17-SEP-2002) to the EMBL/GenBank/DDBJ databases. RL McDonald I., University of Warwick, Biological Sciences Dept., Coventry CV4 RL 7AL, UK. XX RN [5] RX DOI; 10.1099/mic.0.26060-0 RX PUBMED; 12855729. RA Stafford G.P., Scanlan J., McDonald I.R., Murrell J.C.; RT "rpoN, mmoR and mmoG, genes involved in regulating the expression of RT soluble methane monooxygenase in Methylosinus trichosporium OB3b"; RL Microbiology (Reading, Engl.) 149(Pt 7):1771-1784(2003). XX FH Key Location/Qualifiers FH FT source 1..10144 FT /organism="Methylosinus trichosporium" FT /isolate="OB3b" FT /mol_type="genomic DNA" FT /db_xref="taxon:426" FT CDS 234..2183 FT /transl_table=11 FT /gene="mmoR" FT /product="sigma 54 dependent transcriptional regulator FT MmoR" FT /db_xref="GOA:Q84EU9" FT /db_xref="InterPro:IPR002078" FT /db_xref="InterPro:IPR002197" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR009057" FT /db_xref="InterPro:IPR020441" FT /db_xref="UniProtKB/TrEMBL:Q84EU9" FT /protein_id="CAD61955.1" FT /translation="MRQTGQAPSGADWVRPQVAEAWARCIDEHALTPGVELAPRLREAD FT APAMEATISPAAAHLAEAAYDLRALLGDAEVALLLTDPDATLIQFFDHGLEMSAGWPMT FT RVGADWSEAAIGNTGVGAACLLREPAAFDGKEHFNRALHRFATAGCPILGPDGRICAII FT GLISARRDSARLMLGCLKIARRVMEASLFEHLVSDGYLLRLRASAFGDPGGRYAAGGRV FT FVAADGRIQGVDRIGRELLEAAAAGALIGEDVGAAIGVELSALKAASDDARAVPVKGRG FT ARLLIADVHRAPRRDASSAAASSAGCGAELAELRACDAEWRDGVLETALRKASGLQERN FT IPILITGESGVGKDHLVRRLHAIGPRKDRPLVAINCAAIPRELIESELFGYEGGSFTGA FT RAKGKPGKFVEADKGILFLDEIGDMAADLQATLLRVLDSSEVVPIGSSKPIRVDVRVVA FT ATNRSLPEMVQKGTFRRDLYYRLNGVQLWLPPLRERPDRLRLLAHLFRIEQEQLGVAEA FT HSFADEVWRVFLQHPWPGNIREARNVLRSSIAVARERIIRIEDLPVDFMQELNVDSRRQ FT LDASLLGEHRLEESGETSLDLSDWEARAVRFALASSNGNIAKAARSLGITRATLYHKMA FT RYGLQSDRRIISKR" FT CDS 2518..4263 FT /transl_table=11 FT /gene="mmoG" FT /product="GroEL homologue" FT /db_xref="GOA:Q83WK3" FT /db_xref="HSSP:1JON" FT /db_xref="InterPro:IPR001844" FT /db_xref="InterPro:IPR002423" FT /db_xref="UniProtKB/TrEMBL:Q83WK3" FT /protein_id="CAD61956.1" FT /translation="MTNPRKRERRRPAFDVTREKFVARNIRFGDVVRRDLLAGVDALAD FT AVAVTLGPRGRNVVIEHRAAGLPPVATKDGVTVAQAVELAGRTQSVGVSLVRQMATAVA FT KEAGDGTTTSVVLARRLAAETRKALAAGMNPRDIVLGMEKAARIVDRDLAARARRCDDT FT RALAHVATLAAGGDESIGAIVADALTRAGEGGVVDVELGAALCDEMDIVEGMRWEQGYR FT SPYFMTDSARKIAELENPYILIYDRVINQFSELVPALELVRRQRGSLLIVAENIVEEAL FT PGLLLNHIRKNLCSIAVKGPGYGDSRYEFLHDLAALTGGRAIMEACGEELSNVTMAHLG FT RAKRVVVREDDTVVIGGEGDGAAITERLAAARQQADWITDGDPSKGSPSGKRHDLENLQ FT TRIKALSGKVVTIKAGGLSDILIKERMQRIENALASARAARSDGVVAGGGVGLYRARAA FT LTEATGDTLDQTYGIAIVRAALDEPIRRIAANAGRDAHEFLFELKRSNDDFWGMDMRSG FT ECGDLYAAGVIDPARVTRLALRNAVATASSLMTVECAVTHIPPSDPTYGFDPHLAAATR FT EDPRS" FT protein_bind 4494..4509 FT /gene="mmoX" FT /bound_moiety="sigma 54" FT -35_signal 4454..4459 FT /gene="mmoX" FT -10_signal 4478..4482 FT /gene="mmoX" FT promoter 4493..4498 FT /gene="mmoX" FT promoter 4505..4508 FT /gene="mmoX" FT RBS 4667..4669 FT /gene="mmoX" FT CDS 4672..6252 FT /transl_table=11 FT /gene="mmoX" FT /product="Protein A-alpha subunit of soluble methane FT monooxygenase (sMMO)" FT /function="hydroxylase" FT /db_xref="GOA:P27353" FT /db_xref="InterPro:IPR003430" FT /db_xref="InterPro:IPR009078" FT /db_xref="InterPro:IPR012348" FT /db_xref="PDB:1MHY" FT /db_xref="PDB:1MHZ" FT /db_xref="UniProtKB/Swiss-Prot:P27353" FT /protein_id="CAA39068.2" FT /translation="MAISLATKAATDALKVNRAPVGVEPQEVHKWLQSFNWDFKENRTK FT YPTKYHMANETKEQFKVIAKEYARMEAAKDERQFGTLLDGLTRLGAGNKVHPRWGETMK FT VISNFLEVGEYNAIAASAMLWDSATAAEQKNGYLAQVLDEIRHTHQCAFINHYYSKHYH FT DPAGHNDARRTRAIGPLWKGMKRVFADGFISGDAVECSVNLQLVGEACFTNPLIVAVTE FT WASANGDEITPTVFLSVETDELRHMANGYQTVVSIANDPASAKFLNTDLNNAFWTQQKY FT FTPVLGYLFEYGSKFKVEPWVKTWNRWVYEDWGGIWIGRLGKYGVESPASLRDAKRDAY FT WAHHDLALAAYAMWPLGFARLALPDEEDQAWFEANYPGWADHYGKIFNEWKKLGYEDPK FT SGFIPYQWLLANGHDVYIDRVSQVPFIPSLAKGTGSLRVHEFNGKKHSLTDDWGERQWL FT IEPERYECHNVFEQYEGRELSEVIAEGHGVRSDGKTLIAQPHTRGDNLWTLEDIKRAGC FT VFPDPLAKF" FT RBS 6369..6371 FT /gene="mmoY" FT CDS 6381..7565 FT /transl_table=11 FT /gene="mmoY" FT /product="Protein A-beta subunit of soluble methane FT monooxygenase (sMMO)" FT /function="hydroxylase" FT /db_xref="GOA:P27354" FT /db_xref="InterPro:IPR003430" FT /db_xref="InterPro:IPR009078" FT /db_xref="InterPro:IPR012078" FT /db_xref="InterPro:IPR012348" FT /db_xref="PDB:1MHY" FT /db_xref="PDB:1MHZ" FT /db_xref="UniProtKB/Swiss-Prot:P27354" FT /protein_id="CAA39069.1" FT /translation="MSQPQSSQVTKRGLTDPERAAIIAAAVPDHALDTQRKYHYFIQPR FT WKPLSEYEQLSCYAQPNPDWIAGGLDWGDWTQKFHGGRPSWGNESTELRTTDWYRHRDP FT ARRWHHPYVKDKSEEARYTQRFLAAYSSEGSIRTIDPYWRDEILNKYFGALLYSEYGLF FT NAHSSVGRDCLSDTIRQTAVFAALDKVDNAQMIQMERLFIAKLVPGFDASTDVPKKIWT FT TDPIYSGARATVQEIWQGVQDWNEILWAGHAVMIATFGQFARREFFQRLATVYGDTLTP FT FFTAQSQTYFQTTRGAIDDLFVYCLANDSEFGAHNRTFLNAWTEHYLASSVAALKDFVG FT LYAKVEKSRADRSRRRLRGAAASSAIGRSITPDKIGFRVDVDQKVDAVLAGYKN" FT RBS 7570..7572 FT /gene="mmoB" FT CDS 7581..7997 FT /transl_table=11 FT /gene="mmoB" FT /product="Protein B of soluble methane monooxygenase FT (sMMO)" FT /function="regulatory subunit" FT /db_xref="GOA:P27356" FT /db_xref="InterPro:IPR003454" FT /db_xref="PDB:2MOB" FT /db_xref="UniProtKB/Swiss-Prot:P27356" FT /protein_id="CAA39070.1" FT /translation="MSSAHNAYNAGIMQKTGKAFADEFFAEENQVVHESNAVVLVLMKS FT DEIDAIIEDIVLKGGKAKNPSIVVEDKAGFWWIKADGAIEIDAAEAGELLGKPFSVYDL FT LINVSSTVGRAYTLGTKFTITSELMGLDRALTDI" FT RBS 8013..8016 FT /gene="mmoZ" FT CDS 8023..8532 FT /transl_table=11 FT /gene="mmoZ" FT /product="Protein A-gamma subunit of soluble methane FT monooxygenase (sMMO)" FT /db_xref="GOA:P27355" FT /db_xref="InterPro:IPR004222" FT /db_xref="InterPro:IPR015952" FT /db_xref="InterPro:IPR015953" FT /db_xref="PDB:1MHY" FT /db_xref="PDB:1MHZ" FT /db_xref="UniProtKB/Swiss-Prot:P27355" FT /protein_id="CAA39071.1" FT /translation="MAKREPIHDNSIRTEWEAKIAKLTSVDQATKFIQDFRLAYTSPFR FT KSYDIDVDYQYIERKIEEKLSVLKTEKLPVADLITKATTGEDRAAVEATWIAKIKAAKS FT KYEADGIHIEFRQLYKPPVLPVNVFLRTDAALGTVLMEIRNTDYYGTPLEGLRKEPGVK FT VLHLQA" FT CDS 8616..8924 FT /transl_table=11 FT /gene="mmoD" FT /product="hypothetical protein" FT /note="orfY" FT /db_xref="InterPro:IPR017256" FT /db_xref="UniProtKB/TrEMBL:Q79AS1" FT /protein_id="CAD61957.1" FT /translation="MDQQTAHEVRQTLIHADERYQAYTMDLEYMLRWEILRDGEFVQEG FT CSLSQESAREAVAHVLSHFRRQMLRRRTTAGKAKLRALLAIGTPSPEGRERRGERDI" FT CDS 8937..9959 FT /transl_table=11 FT /gene="mmoC" FT /product="Protein C of soluble methane monooxygenase FT (sMMO)" FT /function="reductase" FT /db_xref="GOA:Q9XB08" FT /db_xref="HSSP:1JQ4" FT /db_xref="InterPro:IPR001041" FT /db_xref="InterPro:IPR001221" FT /db_xref="InterPro:IPR001433" FT /db_xref="InterPro:IPR001709" FT /db_xref="InterPro:IPR008333" FT /db_xref="InterPro:IPR012675" FT /db_xref="InterPro:IPR017927" FT /db_xref="InterPro:IPR017938" FT /db_xref="UniProtKB/TrEMBL:Q9XB08" FT /protein_id="CAB45257.1" FT /translation="MYQIVIETEDGETCRRMRPSEDWISRAEAERNLLASCRAGCATCK FT ADCTDGDYELIDVKVQAVPPDEEEDGKVLLCRTFPRSDLHLLVPYTYDRISFEAIQTNW FT LAEILACDRVSSNVVRLVLQRSRPMAARISLNFVPGQFVDIEIPGTHTRRSYSMASVAE FT DGQLEFIIRLLPDGAFSKFLQTEAKVGMRVDLRGPAGSFFLHDHGGRSRVFVAGGTGLS FT PVLSMIRQLGKASDPSPATLLFGVTNREELFYVDELKTLAQSMPTLGVRIAVVNDDGGN FT GVDKGTVIDLLRAELEKSDAKPDIYLCGPPGMIEAAFAAAATAGVPKEQVYLEKFLASG FT " XX SQ Sequence 10144 BP; 1870 A; 3243 C; 3251 G; 1780 T; 0 other; aagcttctcg cacgaaagcc tgccacgcct cgccgctctt cgcgacgagc ggcgagcacg 60 agcgcgcccg cgccgccgcg gcgcgacgac gttaggattc gggaggatcg cctttgagcg 120 agatcgcagt gagaaagccc gtcctcgagc gcccgcaatc gtcggggccg cggccctgcg 180 gcgaggacgc cggcctccat ggcgtggacc gtcccggcgt cgcctgggat tggatgcgcc 240 agaccggcca ggcgccgagc ggcgccgatt gggtgcgtcc gcaagtggcg gaggcatggg 300 cccgctgcat cgacgagcac gcgctgacgc cgggcgtgga gctcgcgccg cggctccgtg 360 aggccgatgc gccggcgatg gaggcgacga tctctccggc cgccgctcat ctcgcggagg 420 cggcctatga cctgcgcgcg ctgctcggcg acgccgaggt cgcgctgctg ctcaccgatc 480 ccgatgcgac gctgattcaa ttcttcgacc acggcctcga gatgtcggcc ggttggccga 540 tgacgcgcgt cggcgccgat tggagcgagg cggcgatcgg caacaccggc gtcggcgccg 600 cctgtctcct gcgcgagccg gccgctttcg acggcaagga gcatttcaac cgcgcgctgc 660 atcgcttcgc caccgcgggc tgtccgatcc tcgggcccga cggacgcatc tgcgcgatca 720 tcggcctcat ctcggcgcgc cgcgacagcg caaggctgat gctcggctgt ctcaagatcg 780 cccggcgcgt gatggaggcg agcctgttcg agcatctcgt ctcggacggc tatctgctgc 840 gcctgcgcgc gagcgccttc ggcgatcccg gcggacgcta cgccgccggc ggccgtgtgt 900 tcgtcgccgc cgatggtcgc attcagggcg tcgaccgcat cggccgcgag ctgctcgaag 960 ccgccgccgc cggcgcgctg atcggagagg acgtcggcgc cgcgatcggc gtcgagctct 1020 cggctctgaa ggccgcgagc gacgatgcgc gcgcggttcc ggtgaagggc cgcggcgcgc 1080 gtctcctcat cgccgacgtt catcgcgcgc cgcgccgcga cgcctcatcc gcggcggcga 1140 gcagcgcggg ctgcggcgcc gagctggcgg agctgcgcgc ctgcgacgcc gaatggcgcg 1200 acggcgtgct ggagaccgct ctgcgcaaag cctcggggct gcaggagcgc aatattccga 1260 tcctgatcac cggcgaatcc ggcgtcggca aggatcatct cgtgcgccgg ctccacgcca 1320 tcggcccgcg caaggatcgc ccgctcgtcg ccatcaattg cgccgccatt ccgcgcgagc 1380 tgatcgagag cgaattgttc ggctatgagg gcggcagctt caccggcgcg cgcgccaagg 1440 gcaagccggg caagttcgtc gaagccgaca agggaatctt gttcctcgac gagatcggcg 1500 acatggccgc cgatctgcag gcgacgttgc tgcgcgtgct cgattcgagc gaggtcgtgc 1560 cgatcggctc gtcgaagccg atccgcgtcg atgtgcgcgt cgtcgccgcg accaatcgca 1620 gcttgccgga aatggtgcag aagggaacgt ttcgccgcga tctctactat cgcctcaacg 1680 gcgtgcagct gtggctgccg cccttgcgcg agcgtcccga tcggctgcgc ttgctcgcgc 1740 atctctttcg catcgagcag gagcagctcg gcgtcgccga ggcgcacagc tttgccgacg 1800 aggtgtggcg cgtgtttctc cagcatccct ggccgggcaa catcagagaa gcgcgcaatg 1860 tgctgcgctc gtcgatcgcc gtcgcgcgcg agcgcatcat tcgcatcgag gatttgccgg 1920 tcgacttcat gcaggagctg aacgtcgact cgcgtcgcca actcgacgcc tcgctgctgg 1980 gcgagcatag gctcgaggag agcggcgaga cgtcgctcga cctctccgat tgggaggcgc 2040 gcgcggtgcg cttcgcgctc gcctccagca acggcaatat cgccaaggcg gcgcgcagcc 2100 tcggcatcac ccgcgccacc ctctatcaca agatggcgcg ctatggcctg cagagcgaca 2160 ggcgcatcat ttccaagagg tgatgcagtt ctgagaggtg atgaatggga ccggacgatc 2220 gatcctttct agagcagatg gcgacgacgc tcgacgcgtc gattcgcgag ctcgaatccg 2280 acgcggagca tctttccgcg gacatcggcg aggagcgcgt cgccgagctg cgcgccttct 2340 tccgcagaga gctcgagccg atcgatctcg aggagattcg cggcacgctc gatttcgacg 2400 atcgccgtct gctgtcgctg tgggtgcggc tcgagcgcaa tcgcgcgcgg cgcgtcgctg 2460 cgggccgcaa gaccatggcg ctcgacgcgg gacgcgagga catcgacgtc tccgcctatg 2520 acaaatccaa gaaaacgtga gcggcgacga ccggcgttcg acgtgacgag ggagaaattc 2580 gtggctagaa atattcgatt cggagacgtc gtgcgtcgtg atctgctcgc cggcgtcgat 2640 gcgctcgccg acgccgtcgc cgtcacgctc ggcccgcgcg gtcgcaatgt ggtgatcgag 2700 catcgcgccg cggggcttcc gcccgtcgcc accaaggatg gcgtgaccgt cgcgcaggcg 2760 gtcgagctcg cgggccgcac gcagagcgtc ggcgtgtcgc tggtgcggca gatggcgacg 2820 gccgtcgcca aggaggccgg cgacggcacg accacatccg tcgtgctggc gcggcgcctc 2880 gccgccgaga cgcgcaaggc gctcgccgcc ggcatgaatc cgcgcgacat cgtgctcggc 2940 atggagaaag cggcgcgcat cgtcgatcgt gatctcgccg cgcgcgcacg gcgctgcgac 3000 gatacacgcg cgctcgcgca tgtcgcgacg ctggcggcgg gcggcgacga gtcgatcggc 3060 gcaatcgtcg cagacgcctt gacgcgcgcc ggcgaaggcg gcgtcgtcga tgtcgagctc 3120 ggcgccgctc tttgcgacga gatggacatc gtcgaaggca tgcgttggga gcagggctat 3180 cgatcgcctt atttcatgac cgacagcgca cgcaagatcg ccgagctcga gaatccctat 3240 attctgatct atgaccgcgt catcaatcaa ttctccgagc tggtgccggc gctggagctg 3300 gtgcgccgtc agcgcggcag cctgctgatc gtcgccgaga acatcgtcga ggaggctctg 3360 cccggcctct tgctcaatca tatccgcaag aatctctgct cgatcgcggt gaagggtcct 3420 ggttatggcg acagccgcta tgagttcctg cacgatctcg cggcgctgac cggcggacgc 3480 gcgatcatgg aagcctgcgg agaagaattg tccaatgtga cgatggcgca tctcggccgc 3540 gcgaaacgcg tcgtcgtgcg cgaggatgat acggtggtga tcggcggcga gggcgacggc 3600 gcggcgatca ctgagcgtct cgccgcggcg cggcagcagg cggattggat caccgatggc 3660 gatccgtcga agggctcgcc cagcggcaag cgtcatgatc tcgaaaatct gcagacgcgc 3720 atcaaggcgc tctcgggcaa ggtcgtcacc atcaaggccg gcggactctc ggatattctg 3780 atcaaggaac gcatgcaacg catcgagaat gccctcgcct cggcgcgcgc cgcgcgcagc 3840 gacggcgtcg tcgccggcgg cggcgtcggg ctctatcgcg cgcgcgccgc tctcaccgaa 3900 gcgacgggcg acactctcga tcagacctat ggaatcgcta ttgtgcgcgc ggcgctcgac 3960 gagccgatcc gtcgcatcgc cgccaatgcg gggcgcgatg cgcatgagtt tttattcgag 4020 ctcaaacgtt cgaacgatga tttctggggc atggacatgc gcagcggcga atgcggcgat 4080 ctctatgcgg cgggcgtcat cgatccggcg cgcgtcacgc gtctcgcatt gcgcaacgcc 4140 gtcgccaccg catcgtcatt gatgaccgtc gaatgcgcgg tcactcatat tccgccgagc 4200 gatccgacat acggcttcga tccgcatctc gccgctgcga cgcgtgaaga tccgcgcagc 4260 tgaagcagcg aatggcgaaa gaatgaaagc gctgcggcga tgcttcgccg cagcgttttt 4320 ttatgcgcgg atgcgcccgt gatttcatcg aatgcagtca tcatcacgat acgtatggtt 4380 ctttgacatg tgtatcgcgc atcgccatag cacgatcatt tttacgcgtc gcacgtagtt 4440 gcgaatgcga cgaatcccaa caaataccga tgaaatctat tatccgcagc gagtggcaca 4500 ggccttgcca aataagaagc gtcgacgctt ccgcgcagat gcgcaaggac gagagacgtt 4560 tcgaaaaccc gaggtttgga aagcggcgac gcggttcgga tgatcgacgc gcgcaatgag 4620 cgcgagcacg acggtccgaa acaaaagaaa actctgtcag gaggaacaag catggcgatc 4680 agtctcgcta cgaaagcggc gaccgatgct ctgaaggtca accgcgctcc ggtcggcgtg 4740 gagcctcagg aggtccacaa atggctgcag agcttcaact gggacttcaa agagaaccgg 4800 acgaagtatc cgaccaaata tcacatggcg aatgagacca aggagcagtt caaggtcatc 4860 gccaaggaat acgcccgcat ggaggcggcc aaggacgagc gccagttcgg cactcttctc 4920 gacggcctca cccgcctcgg cgccggcaac aaggtccatc cccgctgggg cgagacgatg 4980 aaggtgatct cgaacttcct cgaggtcggc gaatataacg cgatcgccgc ttcggccatg 5040 ctttgggaca gcgccaccgc cgccgagcag aagaacggct atctcgcgca ggtgctcgac 5100 gagattcgtc acacgcatca atgcgccttc atcaatcact attactccaa gcattatcac 5160 gatccggccg gccacaatga cgcccgtcgc acgcgcgcga tcggtccgct gtggaagggc 5220 atgaagcgcg tcttcgccga cggcttcatc tccggcgacg ccgtggagtg ctcggtcaat 5280 ctgcagctgg tcggcgaagc ctgcttcacc aatccgctca tcgtcgccgt caccgaatgg 5340 gcttcggcca atggcgacga gatcacgccg accgtgttcc tctcggtgga gaccgacgag 5400 ctgcgtcata tggcgaacgg ctaccagacc gtggtgtcga tcgccaatga tccggcttcg 5460 gcgaagttcc tcaacaccga tctgaacaac gccttctgga cgcagcagaa atatttcacg 5520 cccgtcctcg gctatctgtt cgagtatggc tccaagttca aggtcgagcc ctgggtgaag 5580 acctggaacc gctgggtcta cgaggattgg ggtggaatct ggatcggccg tctcggcaaa 5640 tatggcgtcg agagcccggc gtcgctgcgc gacgccaagc gcgacgctta ctgggcgcat 5700 cacgatctgg cgctcgccgc ctatgcgatg tggccgctcg gcttcgcgcg tctcgctctt 5760 cccgacgagg aagatcaggc gtggttcgag gcgaattatc cgggctgggc cgatcactac 5820 ggcaagatct tcaacgagtg gaagaagctc ggctatgaag atcccaagag cggcttcatc 5880 ccctatcagt ggctcctcgc gaacggtcac gacgtctata tcgaccgtgt ctcgcaggtt 5940 ccgttcattc cgtcgctggc caagggcacg ggctcgctgc gcgtgcacga gttcaacggc 6000 aagaagcatt cgctgacgga tgattggggt gagcgccagt ggctgatcga gccggagcgc 6060 tacgagtgcc acaacgtctt cgagcagtat gagggacgcg aattgtccga ggtgatcgcc 6120 gagggccatg gcgttcgctc cgacggcaag acgctgatcg ctcagccgca cacgcgcggc 6180 gacaatctgt ggacgctcga ggacatcaag cgggccggct gcgtgttccc cgatccgctc 6240 gccaaattct gatctcacga gattccggcg cgcgtcgctc gcaacgcgcg tcggatgaac 6300 cgccgggcct cccgcgtccg gcgtctcctt cgacgcgagc acgaagcacc aaaaatcctt 6360 ctgtggagga agaactcacc atgtcacagc ctcagagctc ccaagtcacc aagcggggtc 6420 tcaccgatcc cgagcgtgcg gccatcatcg ccgccgctgt gccggatcat gcgctcgaca 6480 cgcagcgcaa atatcactac ttcatccagc cgcgctggaa gccgttgtcg gaatatgagc 6540 agctctcctg ctatgcgcag cccaatcccg actggatcgc cggcggcctc gattggggcg 6600 attggacgca gaagttccat ggcggccgtc cgtcctgggg caatgagagc accgagctgc 6660 gcacgaccga ctggtatcgt catcgcgatc cggcccgtcg ctggcatcac ccctatgtga 6720 aggacaagtc ggaagaggcg cgctacaccc agcgctttct cgccgcttat tcgtccgaag 6780 gctcgatccg caccatcgac ccctattggc gcgacgagat cctgaacaaa tatttcggcg 6840 ctctactcta cagcgaatac ggcttgttca acgcgcattc gtcggtcggc cgcgactgcc 6900 tgtcggacac gatccgtcag acggcggtgt tcgcggcgct cgacaaggtc gacaatgcgc 6960 agatgatcca gatggagcgt ctgttcatcg ccaagctggt gccgggcttc gacgcttcga 7020 ccgacgtgcc gaagaagatc tggaccaccg atccgatcta ttctggcgcc cgcgcgacgg 7080 tgcaggagat ctggcagggc gttcaggatt ggaacgagat cctctgggcg ggccacgccg 7140 tcatgatcgc gaccttcggc caattcgccc gtcgcgagtt cttccagcgc ctcgccaccg 7200 tctatggcga cacgctgacg cccttcttca cggcgcagtc gcagacctat ttccagacca 7260 cgcgcggcgc gatcgacgat ctcttcgtct attgcctcgc caatgattcg gaattcggcg 7320 cgcacaaccg caccttcctc aacgcttgga ccgagcatta tctcgcgagc tcggttgccg 7380 cgctgaagga cttcgtcggt ctctacgcca aggtcgagaa gtcgcgcgcg gaccgatcgc 7440 gccggcgtct ccgaggcgct gcagcgtctt cggcgattgg aagatcgatt acgcccgaca 7500 agatcggctt cagggtcgac gtggaccaga aggtcgacgc cgttctcgcc ggctacaaga 7560 actgaaaagg aaacgcttca atgtccagcg ctcataacgc ttacaacgcc ggcatcatgc 7620 agaagaccgg caaggccttc gcggacgagt tcttcgccga ggagaaccag gtcgtccacg 7680 agtccaacgc cgtggttctg gtgctgatga agagcgacga gatcgacgcc atcatcgagg 7740 acatcgtcct caagggcggc aaggcgaaga atccgtcgat cgtcgtcgag gacaaggcgg 7800 gcttctggtg gatcaaggcc gatggcgcga tcgagatcga cgcggcggaa gccggcgagc 7860 tgctcggcaa gccgttctcg gtctacgacc ttctcatcaa tgtgtcgtcg acggtcggcc 7920 gcgcctacac gctcggcacc aaattcacca tcacctcgga actcatgggc ctcgatcgcg 7980 ccctgaccga catctgatcg gtcgtcgaca aggaacgcca caatggccaa gagagaaccc 8040 atccacgaca attccattcg caccgaatgg gaagcgaaga tcgccaagct gacgagcgtc 8100 gatcaggcga cgaagttcat ccaggacttc cgcctcgcct acacgtcgcc cttccgcaag 8160 agctacgata tcgacgtcga ttatcagtat atcgagcgca agatcgagga gaagctctcg 8220 gtgctgaaga ccgagaagct tcccgtcgcc gacctcatca ccaaggcgac gaccggcgag 8280 gaccgcgccg cggtggaggc gacctggatc gccaagatca aggccgccaa gagcaaatat 8340 gaggcggacg gcatccacat cgagttccgg cagctctaca agccgccggt tctgccggtg 8400 aatgtgttcc tgcgcacgga tgcggcgctc ggcacggtgc tgatggagat ccgcaacacc 8460 gattattacg gcactccgct cgaagggctg cgcaaggagc cgggcgtcaa ggtcctgcat 8520 ctgcaggcgt gacggcgtga cggtacgcat tggcgaaaga catgcgttcg ggcggccgcg 8580 tcgcccgaac gacaaagaaa agcgggagga cgaaaatgga ccaacagacg gcgcacgaag 8640 tccggcaaac cttgattcac gccgacgagc gctatcaagc ctatacgatg gacctcgaat 8700 atatgttgcg atgggagatt ctgcgcgacg gcgagttcgt gcaggagggc tgctctctgt 8760 cgcaggagtc ggcgcgcgag gcggtcgctc atgtgctgag ccactttcgc cgacagatgc 8820 tacgtcgcag aacgacggcg ggaaaagcga agctccgcgc gctgctggcg atcggaacgc 8880 cgagccctga aggacgagaa cggcgcggcg aacgcgatat ttagggttcg agacttatgt 8940 accagatcgt catcgagacc gaggacggag aaacctgtcg tcgaatgcgg cccagcgagg 9000 attggatctc gcgggctgag gcagagcgta atctgctcgc ctcctgccga gccggctgcg 9060 ccacctgcaa ggccgattgc acggacggcg attatgagct gatcgatgtg aaggtccagg 9120 ccgtgccgcc ggacgaggag gaggacggca aggttctgct gtgccgcacc tttccgcgca 9180 gcgatctgca tctcctcgtg ccttacacct atgatcgcat ctccttcgag gcgattcaga 9240 ccaattggct cgccgagatc ctcgcctgtg atcgcgtgtc gtccaatgtc gtgcgtctcg 9300 tgctgcagcg ctcacggccg atggcggcgc gcatctcgct caatttcgtt cccggccaat 9360 tcgtcgacat cgagataccg ggcacgcata cacggcgctc ctactccatg gcctcggtcg 9420 cggaggatgg gcagctcgaa ttcatcatcc gtctgctgcc ggacggcgcc ttctcgaaat 9480 tcctgcaaac ggaagcgaag gtcggcatgc gcgtcgatct gcgcggaccg gcgggctcgt 9540 tcttcctgca tgatcacggc ggcagatcgc gcgtgttcgt cgccggcggc acgggattgt 9600 cgccggtgct gtcgatgatc cgccagctcg gcaaggcgag cgatccgtcg ccggcgacgc 9660 ttctgttcgg cgtcaccaat cgcgaggaat tgttctatgt cgacgagctg aagactctcg 9720 cgcaatccat gccgaccctc ggcgtgcgca tagcggtggt caatgacgac ggcggcaatg 9780 gcgtcgacaa gggaacggtg attgatcttc tgcgggccga gctcgagaag tccgacgcca 9840 agccggacat ctatctctgt ggtcctcccg gcatgatcga ggccgctttc gcggcggcgg 9900 cgacggcggg cgtgcccaag gagcaagtct atctcgagaa attcctggcg agcggctgat 9960 ccgtcgccgc cttccttctt cgctccgact cttctcttcg gtcgagcggg ggctccccaa 10020 cttctcctgc ccgggctcgc tcgggcagtt tttctttgac gatcgctatc cttcgagccc 10080 cagcgccggc gactttctcg gaatagccgt agagatcgcc gcgcaattgc aggcgttccg 10140 ctct 10144 // |
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