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EBI DbfetchID X14805; SV 1; linear; mRNA; STD; MUS; 5267 BP. XX AC X14805; XX DT 23-NOV-1989 (Rel. 21, Created) DT 24-SEP-2008 (Rel. 97, Last updated, Version 18) XX DE Mus musculus mRNA for DNA methyltransferase 1 XX KW DNA methyltransferase 1; DNA(cytosine-5-)-methyltransferase; Dnmt1 gene. XX OS Mus musculus (house mouse) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; OC Muridae; Murinae; Mus. XX RN [1] RC revised by [3] RA Bestor T.; RT ; RL Submitted (03-MAR-1989) to the EMBL/GenBank/DDBJ databases. RL Bestor T., Harvard Medical School, LHRRB, 45 Shattuck St, Boston, MA 02115, RL U S A. XX RN [2] RP 1-4973 RX DOI; 10.1016/0022-2836(88)90122-2 RX PUBMED; 3210246. RA Bestor T., Laudano A., Mattaliano R., Ingram V.; RT "Cloning and sequencing of mammalian DNA methyltransferase"; RL J. Mol. Biol. 203(4):971-983(1988). XX RN [3] RC Revised by [4] RA Bestor T.H.; RT ; RL Submitted (10-FEB-1992) to the EMBL/GenBank/DDBJ databases. RL Bestor T.H., Harvard Medical School, LHRRB, 45 Shattuck St, Boston, MA RL 02115, U S A. XX RN [4] RP 1-5267 RA Bestor T.H.; RT ; RL Submitted (08-JUL-1996) to the EMBL/GenBank/DDBJ databases. RL Bestor T.H., Genetics & Development, Columbia University, 701 W. 168th St., RL New York, 10032 USAU S A. XX RN [5] RP 1-5267 RX DOI; 10.1074/jbc.271.49.31092 RX PUBMED; 8940105. RA Yoder J.A., Yen R.C., Vertino P.M., Bestor T.H., Baylin S.B.; RT "New 5' regions of the murine and human genes for DNA RT (cytosine-5)-methyltransferase"; RL J. Biol. Chem. 271(49):31092-31097(1996). XX DR ASTD; TRAN00000167496. DR Ensembl-Gn; ENSMUSG00000004099; Mus_musculus. DR Ensembl-Tr; ENSMUST00000004202; Mus_musculus. XX FH Key Location/Qualifiers FH FT source 1..5267 FT /organism="Mus musculus" FT /mol_type="mRNA" FT /clone_lib="70Z" FT /cell_line="Friend murine" FT /cell_type="erythroleukemia" FT /db_xref="taxon:10090" FT CDS 80..4942 FT /gene="Dnmt1" FT /product="DNA methyltransferase 1" FT /EC_number="2.1.1.37" FT /db_xref="GOA:P13864" FT /db_xref="InterPro:IPR001025" FT /db_xref="InterPro:IPR001525" FT /db_xref="InterPro:IPR002857" FT /db_xref="InterPro:IPR010506" FT /db_xref="InterPro:IPR017198" FT /db_xref="InterPro:IPR018117" FT /db_xref="MGI:94912" FT /db_xref="UniProtKB/Swiss-Prot:P13864" FT /protein_id="CAA32910.1" FT /translation="MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVREK FT LNLLHEFLQTEIKSQLCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGTHTLTQKAN FT GCPANGSRPTWRAEMADSNRSPRSRPKPRGPRRSKSDSDTLFETSPSSVATRRTTRQTT FT ITAHFTKGPTKRKPKEESEEGNSAESAAEERDQDKKRRVVDTESGAAAAVEKLEEVTAG FT TQLGPEEPCEQEDDNRSLRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSR FT PRSQPRDPAAKRRPKEVRARAGSSRDSEDRDEDEREEKRRKTTRKKLESHTVPVQSRSE FT RKAAQSKSVIPKINSPKCPECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSIYDSTST FT WFDTYEDSPMHRFTSFSVYCSRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGI FT NGKNLGPINQWWLSGFDGGEKVLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIV FT VEFLQNNPDAVYEDLINKIETTVPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDD FT ETPIFLSPCMRALIHLAGVSLGQRRATRRVMGATKEKDKAPTKATTTKLVYQIFDTFFS FT EQIEKYDKEDKENAMKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCP FT NLAVKEADDDEEADDDVSEMPSPKKLHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVS FT IDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSD FT PLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGTDPETTLPGAEDGKTYFFQLW FT YNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDGRVYCSSIT FT KNGVCYRLGDSVYLPREAFTFNIKVASPVKRPKKDPVKENPVPRDTYRKYSDYIKGRNL FT DAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLCWS FT DEEAVVNFSDVQGRCTVEYREDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHAR FT SPGNKGKGKGKGKGKGKHQVSEPKEPEAAIKLPKLRTLDVFSGCGGLSEGFHQAGISET FT LWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCG FT GPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSYRRSMVLK FT LTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQ FT LSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIQNGASNSEIPYNGEPLSWFQRQ FT LRGSHYQPILRDHICKDMSPLVAARMPHIPLFPGSDWRDLPNIQVRLGDGVIADKLQYT FT FHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPWCLPHTGNRHNHWAGLYGRLE FT WDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDSYRFFGNILDRHRQVG FT NAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD" FT polyA_site 5253 FT /note="polyA site" XX SQ Sequence 5267 BP; 1391 A; 1356 C; 1452 G; 1068 T; 0 other; gcccctccca attggtttcc gcgcgcgcga aaaagccggg gtctcgttca gagctgttct 60 gtcgtctgca acctgcaaga tgccagcgcg aacagctcca gcccgagtgc ctgcgcttgc 120 ctccccggca ggctcgctcc cggaccatgt ccgcaggcgg ctcaaagact tggaaagaga 180 tggcttaaca gaaaaggagt gtgtgaggga gaaattaaac ttactgcatg aattcctgca 240 aacagaaata aaaagccagt tgtgtgactt ggaaaccaaa ttacataaag aggaattatc 300 tgaggaaggc tacctggcta aagtcaagtc cctcttaaat aaggatttgt ccttggagaa 360 cggaacacac actctcactc aaaaagccaa cggttgtccc gccaacggga gccggccaac 420 ctggagagca gaaatggcag actcaaatag atccccaaga tccaggccca agcctcgggg 480 acccaggaga agcaagtcgg acagtgacac cctttttgaa acttcaccta gttccgtggc 540 tacgaggaga accaccaggc agaccaccat cacggctcac ttcacgaagg gccccactaa 600 acggaaaccc aaggaagagt cggaagaggg gaactcggct gagtcggctg cagaggagag 660 agaccaggat aagaaacgca gagttgtaga cacagagagt ggtgctgcag ctgctgtgga 720 gaaactggaa gaggtaacag cgggaaccca gctgggtccg gaagagccat gtgaacagga 780 agatgacaac aggagtcttc gacgtcacac cagagagctg tcattgaggc ggaaatcaaa 840 ggaggatcca gacagagaag caagaccgga aactcacttg gacgaggacg aggacggaaa 900 aaaggataaa agaagttcca gacccaggag ccagcccaga gatccagctg ccaaacggag 960 acccaaggaa gtcagagcca gagcaggtag ctccagagac tccgaggaca gagacgagga 1020 tgagagggag gagaagagac gaaaaacgac acgtaaaaaa ctggagtcac acaccgttcc 1080 cgttcagagc agatcggaga gaaaagccgc tcaaagcaaa agtgtgatcc cgaagatcaa 1140 ctcaccaaag tgccccgagt gtggccagca cctagacgac cctaacctga agtaccagca 1200 gcaccctgag gatgctgtgg atgaacccca gatgttgacc agtgagaaac tgtccatcta 1260 cgactccacc tcgacctggt ttgatactta tgaagattct cccatgcata ggttcacttc 1320 cttcagtgtg tactgcagtc gcgggcacct gtgtcctgtc gacaccggtc tcattgagaa 1380 gaatgtagag ctctactttt ctgggtgtgc caaagcaatt catgacgaga atccatctat 1440 ggaaggtggt attaatggca aaaacctcgg gccaatcaat cagtggtggc tcagtggctt 1500 tgatggtggc gagaaggtgc tcattggctt ctccactgca tttgctgaat acattttgat 1560 ggagcccagc aaagagtatg agccaatatt tgggctgatg caggagaaaa tttacatcag 1620 caagattgtt gttgagttcc tgcaaaacaa tcctgatgct gtatatgaag acctgatcaa 1680 taagattgag accactgttc ctccttctac cattaatgtg aaccggttca cagaggactc 1740 cctcttacgc cacgcccagt ttgtagtgag ccaggtagag agttacgacg aagccaagga 1800 cgatgatgag acccccatct tcttgtctcc ctgtatgaga gccctgatcc atttggctgg 1860 tgtctccctg ggacagaggc gagcaacaag gcgcgtcatg ggtgctacca aggagaagga 1920 caaagcaccc acgaaagcca ccaccaccaa gctggtctat cagatctttg acactttctt 1980 ctcagagcag attgagaagt atgataagga ggacaaggag aatgccatga agcgccgccg 2040 ctgtggtgtc tgtgaggtct gtcagcagcc tgagtgtggg aagtgcaagg cgtgcaaaga 2100 tatggtgaag tttggtggca ctggacggag taagcaggct tgcctcaaga ggaggtgtcc 2160 taacttggcg gtgaaggagg cagacgacga tgaagaggct gatgatgatg tgtcagagat 2220 gccatcaccc aaaaagctgc atcaggggaa gaagaagaag cagaacaagg accgcatctc 2280 ctggcttggg cagcctatga agattgaaga gaatagaact tactatcaga aggtgagcat 2340 cgatgaggag atgctagagg tgggcgactg cgtctcggtc attccagatg attcctccaa 2400 accactctat ctagccaggg tcacagctct gtgggaagac aaaaatggtc agatgatgtt 2460 ccatgcgcac tggttctgcg ctgggacaga cacagtcctg ggagccacct ccgaccccct 2520 ggaactgttc ctggtgggcg agtgcgaaaa catgcagctt tcctacatcc acagcaaggt 2580 caaggtcatc tacaaagccc cttctgaaaa ctgggccatg gagggaggca cagaccctga 2640 gaccacactg cctggggctg aggatggcaa gacttacttc ttccagctct ggtacaacca 2700 ggagtacgca aggtttgaat ccccacccaa gacccagccg accgaggaca acaagcacaa 2760 gttctgccta tcttgtatcc ggctggctga gctgagacaa aaagaaatgc ccaaggtcct 2820 ggaacaaatt gaggaggtgg atggccgggt ctactgcagt tccatcacca agaatggtgt 2880 ttgctaccga ctgggtgaca gtgtgtacct tcctcgggag gcctttactt tcaacatcaa 2940 agtggctagc cccgtgaaac gcccaaagaa ggatcctgtg aaagagaacc ctgtacccag 3000 agacacatac agaaagtatt ctgactacat caaggggaga aacctggatg ctccagagcc 3060 ctatcgcatc ggtcggataa aagagatcca ctgtggcaag aagaaaggca aggtgaacga 3120 ggcagacatc aagctgaggc tctacaagtt ctacaggcct gagaataccc acaggtccta 3180 caacggatcc tatcacactg acatcaacat gctttgctgg agcgacgagg aagctgtggt 3240 gaacttcagc gacgtgcagg gccgctgtac cgtggagtac cgggaagacc tacttgagag 3300 catccaggat tattcacaag ggggccctga ccgcttctac ttcctcgagg cctacaattc 3360 aaagaccaag aactttgaag acccaccaaa ccatgcccgc agccctggga acaaagggaa 3420 agggaagggg aaagggaagg ggaaggggaa gcatcaggtg tcagagccca aagagcctga 3480 ggcagccatc aaactgccca agctccggac cctggatgtg ttttccggct gtggagggtt 3540 atcggaagga ttccaccaag caggcatctc ggaaaccctg tgggccatcg agatgtggga 3600 cccggcagcc caggcatttc ggctgaacaa ccccggcacc acagtgttca cagaggactg 3660 caacgtgctt cttaagctgg tcatggctgg ggaggtgacc aactctctgg gccaaaggct 3720 gccacagaag ggcgatgtgg agatgctgtg tggtgggcca ccctgccagg gcttcagtgg 3780 catgaaccgc ttcaactccc gcacttactc caagttcaaa aactccctag tggtctcctt 3840 cctcagctac tgtgactact accggcctcg gttcttcctt ctggagaacg tcaggaactt 3900 cgtgtcctac agacgctcca tggtgctgaa gctcacactg cgctgcctgg tccgcatggg 3960 ctaccagtgc acctttggtg tgctccaggc tggacagtat ggcgtggccc agacacgaag 4020 gagggccatc atcttggctg cagccccagg agaaaagctg cctctgttcc cagagcctct 4080 gcatgtgttt gcgccccgtg cctgccagct gagcgttgtg gtggatgaca agaagtttgt 4140 tagcaacata acgaggctga gctcggggcc cttccgaacc atcaccgtgc gagacaccat 4200 gtctgacctc cccgagatcc agaatggagc ctcgaattct gagatcccct acaatggaga 4260 gccactgtcc tggttccaga ggcagctgcg aggatcacac taccagccca tcctcaggga 4320 ccatatctgc aaggacatga gcccactggt ggctgcccgc atgccgcaca tcccactgtt 4380 cccaggatca gattggcgtg acctgcccaa catacaggtg cggctgggag atggcgtcat 4440 agccgataag ctacagtaca cctttcatga tgtgaaaaat ggctacagca gcaccggtgc 4500 cctgcgtgga gtctgttcct gtgcagaagg caaggcctgc gaccctgagt ccaggcaatt 4560 cagcaccctc atcccctggt gcctgccgca cactgggaac cggcacaacc actgggctgg 4620 cctctacggg cgtctggagt gggatggctt cttcagcacc actgtcacca accctgagcc 4680 catgggcaag cagggtcggg tgctccaccc ggagcagcac cgggtcgtga gtgttcggga 4740 atgtgcccgc tcccagggct ttccagatag ctaccggttc ttcggcaaca tcctggacag 4800 acaccggcag gtgggtaatg ctgtgccacc acccctggcc aaagccattg gcctggagat 4860 taagctctgc ctgctgtcca gtgctcggga gagcgcatca gctgcagtta aagcaaaaga 4920 ggaggctgct accaaggact agtgctctca cccagagccc cacgtgcact gatgttttta 4980 accctttgag ccccatcatt tgaagtcttg tgctcagtgt ctgtggccat ggctgacact 5040 aagctgtttg tatgaggttt gttttgtgac caagctgtgt agtactttgt gcattctgaa 5100 ttttaaggtt tttttttttg tttggtttgg tttggtttgg tttttttctt atcctgtatt 5160 ctatcagatc tgccactgtg caggtggcaa gtgagacttg atgtagtttt atatgttgta 5220 atatttcttc aaaataaagc gcttctgtca agcaaaaaaa aaaaaaa 5267 // |
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