EBI Dbfetch

ID   U95360; SV 1; linear; genomic DNA; STD; PRO; 1885 BP.
XX
AC   U95360;
XX
DT   29-MAY-1997 (Rel. 52, Created)
DT   31-AUG-2006 (Rel. 89, Last updated, Version 4)
XX
DE   Sulfolobus solfataricus 3-hydroxy-3-methylglutaryl coenzyme A reductase
DE   (HMG-CoA) gene, complete cds.
XX
KW   .
XX
OS   Sulfolobus solfataricus
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
XX
RN   [1]
RP   1-1885
RX   PUBMED; 9171410.
RA   Bochar D.A., Brown J.R., Doolittle W.F., Klenk H.P., Lam W., Schenk M.E.,
RA   Stauffacher C.V., Rodwell V.W.;
RT   "3-hydroxy-3-methylglutaryl coenzyme A reductase of Sulfolobus
RT   solfataricus: DNA sequence, phylogeny, expression in Escherichia coli of
RT   the hmgA gene, and purification and kinetic characterization of the gene
RT   product";
RL   J. Bacteriol. 179(11):3632-3638(1997).
XX
RN   [2]
RP   1-1885
RA   Bochar D.A., Brown J.R., Doolittle W.F., Klenk H.P., Lam W., Schenk M.E.,
RA   Stauffacher C.V., Rodwell V.W.;
RT   ;
RL   Submitted (27-MAR-1997) to the EMBL/GenBank/DDBJ databases.
RL   Biochemistry, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1885
FT                   /organism="Sulfolobus solfataricus"
FT                   /strain="P2"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:2287"
FT   CDS             329..1558
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="HMG-CoA"
FT                   /product="3-hydroxy-3-methylglutaryl coenzyme A reductase"
FT                   /EC_number="1.1.1.34"
FT                   /db_xref="GOA:O08424"
FT                   /db_xref="InterPro:IPR002202"
FT                   /db_xref="InterPro:IPR004554"
FT                   /db_xref="InterPro:IPR009023"
FT                   /db_xref="InterPro:IPR009029"
FT                   /db_xref="UniProtKB/Swiss-Prot:O08424"
FT                   /protein_id="AAC45370.1"
FT                   /translation="MKIDEVVEKLVKGEISFHEVDNLLEANAAMVARRLALEKIVGVGL
FT                   PSIGSTVIDYSEIKNKNAENVIGAIQIPLGIVGPIRVNGDYAKGDFYVPMATTEGALIA
FT                   SVNRGIKAVTLSGGVRAKVLKDEMTRAPVFKFDSIEQIPNFLKFIEENLEKIRNIANST
FT                   SHHGKLKSITPFVLGNNVWLRFSFETGDAMGMNMVTIAVEKVCEFIEENFPSADCLAVS
FT                   GNMCSDKKQTNVNSLFGRGKTVLAEALIKKDVIRNILHSNAQLIHDINLRKNWLGTARA
FT                   GSLSQFNAHFANIVTAIFIATGQDVAQIVESSSGYTWTEVRGEDLYISVTLPSLEVGTV
FT                   GGGTRLPTQKEALSIMGVYGSGNPPGSNAKKLAEIIASTVLSGELNLLAALSNKELGKA
FT                   HAKLGRAMKV"
XX
SQ   Sequence 1885 BP; 636 A; 288 C; 436 G; 525 T; 0 other;
     aacgttgcgg acatataagc tttccatatt catcgtattg cactaagtgt ggtagtaaaa        60
     acgttaagaa gattgagata agtggcaagg gagtattaga atcctacact gtttcctatc       120
     aatctagaga cgggcacgag aaaggccttc caagtgttat tggtctggtt agactagatg       180
     aaggtgtaga aatagtagca cctatcgtag atgcggattt agataaacta aaagaaggag       240
     ttaaggtaga agctacatta aggagagttt atacggactc atataatggt ttaatacagt       300
     atgggataaa gtttagggta gctgaaggat gaaaattgat gaagtggttg aaaagttagt       360
     aaagggagaa atttcttttc atgaagttga caatttatta gaagcaaatg ctgcaatggt       420
     tgcgaggagg cttgcattag agaagattgt aggagtcggt cttccctcaa ttggttctac       480
     agttattgat tatagtgaga taaaaaataa aaatgccgaa aatgtgattg gagcaataca       540
     aataccatta ggtatagtgg ggccaattag agtcaatggt gattacgcaa agggcgattt       600
     ctatgtacct atggcgacga cagaaggagc gctaatagcc agtgtaaata ggggtatcaa       660
     ggctgttaca ctaagtgggg gagttagggc taaggtttta aaggatgaaa tgacgagagc       720
     ccccgttttt aagtttgatt caatagaaca gataccgaat tttctaaagt tcatagagga       780
     gaatcttgag aagataagga atatagccaa ttctacctct catcatggta aattaaaatc       840
     cattacacct ttcgtactag gcaataatgt ttggcttaga ttttcctttg aaactggtga       900
     tgctatgggg atgaacatgg ttacgatagc agttgaaaaa gtatgtgagt ttatagagga       960
     aaacttccca tcagctgatt gtttagctgt aagcggaaat atgtgtagtg ataagaaaca      1020
     gaccaatgtc aatagcctct tcggtagagg taaaactgta ctggctgagg ctctcatcaa      1080
     gaaggatgtt ataaggaata tattacactc taatgctcaa ctaattcatg atataaatct      1140
     acggaagaat tggctcggga cagcaagagc aggatcctta tctcaattta atgctcattt      1200
     cgcaaacata gtcacagcaa tctttatagc tactggccaa gatgtagctc aaatagttga      1260
     gagtagttct ggatatacat ggactgaagt aagaggagag gacttatata tatcagttac      1320
     actgccctcg ttagaagtag gaactgtagg aggaggtaca aggttaccta cccagaaaga      1380
     agccctatcc attatgggag tttacggcag tggaaatcca cctggctcta atgctaagaa      1440
     attagctgag atcatagctt ctactgtact atctggggaa cttaatctcc tagctgcttt      1500
     atccaacaag gagttaggta aggctcacgc taaacttgga agagctatga aagtctaatc      1560
     tttttatcaa agtttaaata ttctgtaact actttactct tatgtcactt cctaaagaat      1620
     tagaaaaagt tcttgaaatt actaaggcac agaacgtatg gagaaggacg cagactttga      1680
     accttattgc atctgaaaac gtaatgagtc cactagctga aagtgtgtat atgagtgact      1740
     tcatgtcaga tatgcagaag gtaaaccata caagagatac tatcaaggga ccaagtatac      1800
     tgatgaaatc gagactctta ctatggagtt gatgaatgag ataacaaact caaaggattg      1860
     tgatctaaga cctactagcg gtacc                                            1885
//