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EBI DbfetchID U80910; SV 1; linear; mRNA; STD; INV; 3271 BP. XX AC U80910; XX DT 29-SEP-1997 (Rel. 52, Created) DT 29-SEP-1997 (Rel. 52, Last updated, Version 1) XX DE Trypanosoma brucei ribonucleotide reductase large subunit (RNR1) mRNA, DE complete cds. XX KW . XX OS Trypanosoma brucei OC Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma. XX RN [1] RP 1-3271 RX DOI; 10.1073/pnas.94.13.6959 RX PUBMED; 9192674. RA Hofer A., Schmidt P.P., Graslund A., Thelander L.; RT "Cloning and characterization of the R1 and R2 subunits of ribonucleotide RT reductase from Trypanosoma brucei"; RL Proc. Natl. Acad. Sci. U.S.A. 94(13):6959-6964(1997). XX RN [2] RP 1-3271 RA Hofer A.; RT ; RL Submitted (03-DEC-1996) to the EMBL/GenBank/DDBJ databases. RL Medical Biochemistry and Biophysics, Umea University, Umea 901 87, Sweden XX FH Key Location/Qualifiers FH FT source 1..3271 FT /organism="Trypanosoma brucei" FT /strain="427 (TbGARP16)" FT /mol_type="mRNA" FT /dev_stage="procyclic" FT /db_xref="taxon:5691" FT CDS 86..2602 FT /codon_start=1 FT /gene="RNR1" FT /product="ribonucleotide reductase large subunit" FT /db_xref="GOA:O15909" FT /db_xref="InterPro:IPR000788" FT /db_xref="InterPro:IPR005144" FT /db_xref="InterPro:IPR008926" FT /db_xref="InterPro:IPR013346" FT /db_xref="InterPro:IPR013509" FT /db_xref="UniProtKB/Swiss-Prot:O15909" FT /protein_id="AAB70704.1" FT /translation="MLETVKLVTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLV FT RVVGEGVREGMSTSMLDELLAETAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFR FT VLHEHVSQATKRHAPLISEELWDIANKHSAALQQIINYERDFDFEYFGYKTLERSYLLR FT VHKGRGVMEVVERPQQMFLRVALGIHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPF FT PQMSSCFLVAMREDSIDGIYDTLKQCAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNG FT LVPMLRVWNNTARYVDQGGGKRKGAFAIYLEPWHADIFGFLLLKKNTGKEDQRARDLFY FT GLWIPDLFMERVESHGTWTLMDPNTAPFLSDCYGQEFTDLYERYEREGRGVRTIQAQEL FT WFLILESQVETGVPFMLYKDACNFKSNQKNLGTIKCSNLCTEIVEYTSRDEVAVCNLAS FT IALPRFVKDGAFDYVALKEVTKVVTRNLNRVIDRNHYPVCEARYSNLRHRPVGIGVQGL FT ADAFALLSLPFAHPEAKKLNRQIFETIYIAAVEASTELAEKDGPYETFKGSPASEGKLQ FT FDLWDEERRIRGMNEDSVHSHCGLWDWDSLKERVVKVGMRNSLLIAPMPTASTSQILGN FT NECIEPFTSNIYVRRVLSGEFPVVNKHLVKELIRLRLWNDDMRRKIIALNGSVSGIKEI FT PERIRELYKVVWEIRQKDLIDMAADRGRYIDQSQSLNLFLATPTSSQLTSMHFYSWKKG FT LKTGMYYLRSQPAADAIKFTLDPKAMKELPKPDKQSKEEVHGSVGRGKRKRVGEKPTAN FT HSNAGAPNLNGPPDTDGDGGCLNCGS" FT polyA_site 3271 FT /gene="RNR1" FT /note="14 A nucleotides" XX SQ Sequence 3271 BP; 831 A; 686 C; 859 G; 895 T; 0 other; tattgttaaa cacgttggtt ttcaacagag agataggaag cagagcggtt tttaaaaaaa 60 tttttcgttt gcagtaccta aaataatgtt ggaaacggtg aagcttgtga ccaaacgtga 120 tgggtctgtg gaaccgtatg atgaaaaagt cgtgcgcagc cgcatcgtca accttatgtc 180 cgggattgat tcttattatg ttgatgttga tgaccttgtt cgtgtagtgg gggagggggt 240 gcgggaaggt atgagcacct caatgttgga tgaactgctg gctgaaactg ctgcttattg 300 cgtaacaaag catcccgatt acggtctgct ggctggccgg ttggctgtaa cagctttgca 360 caagacgacg acagaaagtg tactggattc ttttagggtg ctacatgaac atgtttcgca 420 ggcaacgaag cggcatgctc cccttatatc agaagaattg tgggatatcg caaataagca 480 ctctgcggcg ttgcagcaaa tcattaatta cgagcgggat tttgattttg agtatttcgg 540 gtacaagaca cttgagcgtt cttacctcct tcgtgtccat aaggggcggg gagttatgga 600 agtggtggag cgtccacaac agatgttcct gcgtgttgcc ctcggtatcc atggagagga 660 cttggaacgt gtgaaggaga catatgacta catgtcgcaa gggtttttta cccacgctac 720 tccaacgtta ttcaatgcgg ggaccccatt cccacaaatg agttcatgct ttcttgtagc 780 tatgcgtgaa gacagtattg atggcatcta cgacacactc aaacagtgtg cgatcatcag 840 caaatcagct ggtgggatcg ggatccacat gcacaacatt cgcgcagcgg ggagctacat 900 cgccgggaca aatggtacgt cgaatggtct ggtccccatg cttcgtgtgt ggaataacac 960 tgctcgctat gttgaccagg gcggtggcaa gcgcaagggc gcctttgcta tttatttgga 1020 gccctggcac gcggatatct ttggtttcct ccttctgaag aaaaatacgg gcaaggagga 1080 tcagcgtgcg cgggacttgt tttacggtct gtggattcct gacctgttta tggaacgagt 1140 tgagagtcat gggacttgga cgcttatgga ccccaacacg gccccctttt tgagtgactg 1200 ttatggccaa gagtttactg atttatatga gcgatatgaa agggaaggtc gtggcgtaag 1260 aactattcag gcccaggaac tgtggttcct tatccttgag tctcaggtgg aaacgggggt 1320 tccttttatg ctttacaagg atgcatgtaa tttcaagtct aatcagaaaa atctcggcac 1380 gataaaatgc tcaaatttgt gcacggaaat tgtcgagtat acttcgaggg acgaggtggc 1440 cgtatgcaac ctagcctcta ttgcccttcc gcgttttgtg aaggatggcg catttgacta 1500 cgttgcattg aaggaggtga caaaggttgt gaccagaaat cttaaccggg tgattgatcg 1560 caaccactat ccagtgtgtg aggcccgata cagtaatttg aggcatcgcc ctgtgggtat 1620 cggtgtccag ggactggcgg atgcgtttgc actgctttcc ctgccattcg cacaccccga 1680 ggcaaagaag ttgaatagac aaatcttcga gaccatttac attgcagctg tggaagcaag 1740 tacggaattg gctgaaaagg acgggcccta tgaaacgttt aaaggaagcc ctgcttcgga 1800 agggaaactg cagtttgatc tgtgggatga ggagcgtagg ataagaggta tgaacgagga 1860 ctctgtgcat tcacactgcg gactctggga ctgggatagc ctcaaggagc gtgtggtcaa 1920 ggtcggtatg cgtaactcgc tgttaattgc gcccatgcca acggcatcta cgtcgcagat 1980 ccttggtaac aatgagtgca tcgaaccctt tacttccaat atctacgtgc gccgggtctt 2040 aagcggggag tttccagttg taaacaaaca ccttgtaaag gagctcattc ggcttcgatt 2100 gtggaacgat gatatgcgaa gaaagattat cgcattaaat ggctctgtta gcggcatcaa 2160 ggagataccg gaacggatca gagagcttta caaggtcgta tgggagatcc gacagaagga 2220 tttgattgac atggcagccg accgggggag gtatatcgat cagagccaga gcctaaatct 2280 ctttctggca acacccacct ccagtcaact cacttctatg catttctatt cgtggaagaa 2340 aggccttaag accggtatgt attacctacg ctctcaacct gccgctgatg ccatcaaatt 2400 tacactcgac cccaaggcaa tgaaagaact gccgaagccg gataagcaaa gtaaagagga 2460 agtacacgga agtgtgggcc gaggaaaaag gaagcgggtt ggggagaagc cgacggcgaa 2520 ccattcaaat gctggagctc ctaatctcaa cggaccccca gacacagacg gtgatggggg 2580 atgcctgaat tgtggttcgt agatgcctct gtagcgtctt ttattcgatg agggccccca 2640 atttagccag tgaagacgat gatccaaaca catgaacagg taattttaca tgagtacgta 2700 tatatgtgta tgtatgtaca tatatatcta tacgtacgat ctcccctctt gactgcgttt 2760 ttgttttttt cgtggatatt tcctccctct taaaagaagg aactttaata cgcggaaaat 2820 gaaggaaaaa ggaattactc tgcaactttt attcttgtta cctctcttcg ttcttctact 2880 cacccggttt tttgtctaca cgttattcct tagacccgtg ttttttttgt gtcgtgcgtg 2940 tggagatgcc gtgaagggat ggacctcggg tgacggggat aactaatatt catttacctt 3000 tctgctcttt tctttttcgt ttttttttct gcgaggccgt cttccccttc tgcgtccgtt 3060 gggataacgg ggataggtgg attcagcgtt gttggagaat ggctaaaata caagatataa 3120 ataaaaaaaa atatgaacaa tagattgggc tgcatttctc cgctatttgt gctctctgca 3180 aggtgtaaat ttttacacgc attcttccgc tttctcagtt tacatagata atttatggct 3240 ctattgcatt tccatggtag ccgttactac a 3271 // |
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