 |
|
EBI DbfetchID U65788; SV 1; linear; genomic DNA; STD; PRO; 3712 BP. XX AC U65788; XX DT 06-MAR-1997 (Rel. 51, Created) DT 18-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Neisseria meningitidis strain 126E glycyl tRNA synthetase (glyS) gene, DE partial cds, and LPS biosynthetic gene locus, lgtA/lgtB, lgtC, lgtD, and DE lgtE genes, complete cds. XX KW . XX OS Neisseria meningitidis OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; OC Neisseria. XX RN [1] RP 1-3712 RA Jennings M.P., Srikhanta Y.N., Moxon E.R., Kramer M., Poolman J.T., RA Kuipers B., van der Ley P.; RT "The genetic basis of the phase variation repertoire of lipopolysaccharide RT immunotypes in Neisseria meningitidis"; RL Microbiology (Reading, Engl.) 145(11):3013-3021(1999). XX RN [2] RP 1-3712 RA Jennings M.P.; RT ; RL Submitted (01-AUG-1996) to the EMBL/GenBank/DDBJ databases. RL Faculty of Science and Technology, Griffith University, Kessels Road, RL Nathan, Queensland 4111, Australia XX FH Key Location/Qualifiers FH FT source 1..3712 FT /organism="Neisseria meningitidis" FT /strain="126E" FT /mol_type="genomic DNA" FT /db_xref="taxon:487" FT CDS <1..231 FT /codon_start=1 FT /transl_table=11 FT /gene="glyS" FT /product="glycyl tRNA synthetase" FT /db_xref="GOA:Q79BU8" FT /db_xref="UniProtKB/TrEMBL:Q79BU8" FT /protein_id="AAB48383.1" FT /translation="FAAAQGLQPKIAAAVAEGNFQTALSELASVKPQVDAFFDGVMVMA FT EDAAVKQNRLNLLNRLAEQMNAVADIALLGE" FT CDS 296..649 FT /codon_start=1 FT /transl_table=11 FT /gene="lgtA/lgtB" FT /note="A fusion between lgtA and lgtB. Presumably the FT result of a deletion event which has removed 81.5% of the FT lgtA coding region and 82.6% of the lgtB coding region FT compared to this region in N. meningitidis strain MC58 FT (GenBank Accession Number U25839). The fusion product is FT presumably inactive" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:P96944" FT /protein_id="AAB48384.1" FT /translation="MQPLVSVLICAYNAEKYFAQSLAAVVNQTWRNLEILIVDDGSTDG FT TLAIAKDFQKWDSRIKILAHDRLLNRKQQRRDSPANTFKHRLIRALTKISREREKRRQR FT REQLIGKIIVPFQ" FT CDS 661..1596 FT /codon_start=1 FT /transl_table=11 FT /gene="lgtC" FT /product="glycosyl transferase" FT /db_xref="GOA:P96945" FT /db_xref="InterPro:IPR002495" FT /db_xref="PDB:1G9R" FT /db_xref="PDB:1GA8" FT /db_xref="UniProtKB/TrEMBL:P96945" FT /protein_id="AAB48385.1" FT /translation="MDIVFAADDNYAAYLCVAAKSVEAAHPDTEIRFHVLDAGISEANR FT AAVAANLRGGGGNIRFIDVNPEDFAGFPLNIRHISITTYARLKLGEYIADCDKVLYLDI FT DVLVRDSLTPLWDTDLGDNWLGACIDLFVERQEGYKQKIGMADGEYYFNAGVLLINLKK FT WRRHDIFKMSCEWVEQYKDVMQYQDQDILNGLFKGGVCYANSRFNFMPTNYAFMANWFA FT SRHTDPLYRDRTNTVMPVAVSHYCGSAKPWHRDCTAWGAERFTELGGSLTTVPEEWRGK FT LAVPHRMFSTKRMLQRWRRKLSARFLRKIY" FT misc_feature 818..830 FT /gene="lgtC" FT /note="homopolymeric tract of 13 G residues" FT CDS 1656..2105 FT /codon_start=1 FT /transl_table=11 FT /gene="lgtD" FT /product="glycosyl transferase" FT /note="similar to lgtD of N. gonorrhoeae. Premature FT termination of the CDS due to a frame shift in a FT homopolymeric tract. An extra G would result in a CDS FT terminating at 2665, analogous to N. gonorrhoeae lgtD FT (GenBank Accession NumberU14554)" FT /db_xref="GOA:P96946" FT /db_xref="HSSP:1QGQ" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:P96946" FT /protein_id="AAB48386.1" FT /translation="MQPLVSVLICAYNAEKYFAQSLAAVVNQTWRNLEILIVDDGSTDG FT TPSIARRFQEQDGRIRIISNPRNLGFMASLNIGLDELVKSGGDILRAPMPTILPPPAGL FT KKSWARWKKTRILPRWEPIWRFWRKKTIKACLPPLPETAKFGKTP" FT misc_feature 1910..1917 FT /gene="lgtD" FT /note="homopolymeric tract; site of frameshift resulting in FT early termination of translation" FT CDS 2684..3526 FT /codon_start=1 FT /transl_table=11 FT /gene="lgtE" FT /product="glycosyl transferase" FT /db_xref="GOA:P96947" FT /db_xref="InterPro:IPR002654" FT /db_xref="UniProtKB/TrEMBL:P96947" FT /protein_id="AAB48387.1" FT /translation="MQNHVISLASAAERRAHIADTFGAHDIPFQFFDALMPSEALEQAM FT AELVPGLSAHPYLSGVEKACFMSHAVLWKQALDEGLPYVAVFEDDVLLGKDAEKFLAED FT TWLEERFDKDSAFIVRLETMFAKVIVRPDKVLNYENRSFPLLESEHWGTAGYIISREAM FT RFFLERFAVLPAERIKAVDWMMFTYFFDKEGMPVYQVNPALCTQELHYAKFLSKNSMLG FT SDLEKDREQERRHRRSLKVMFDLKRALGKFGREKKKRMERQRQAELEKAYGRRVISFK" XX SQ Sequence 3712 BP; 958 A; 883 C; 1001 G; 870 T; 0 other; tttgctgccg cgcaaggctt gcagccgaaa atcgccgccg ccgtcgccga aggcaatttc 60 caaaccgcct tgtccgaact ggcttccgtc aagccgcaag tcgatgcctt ctttgacggc 120 gtgatggtga tggcggaaga tgccgccgta aaacaaaacc gtttgaacct gttgaaccgt 180 ttggcagagc agatgaacgc ggtagccgac atcgcgcttt tgggcgagta accgttgtac 240 agtccaaatg ccgtctgaag ccttcagacg gcatcgtgcc tatcgggaga ataaattgca 300 gcctttagtc agcgtattga tttgcgccta caacgcagaa aaatatttcg cccaatcatt 360 agccgccgtc gtgaatcaga cttggcgcaa cttggagatt ttgattgtcg atgacggctc 420 gacagacggc acacttgcca ttgccaagga ttttcaaaag tgggacagcc gtatcaaaat 480 ccttgcacac gaccgcctcc tgaaccgcaa acagcaaagg cgcgattccc ccgccaacac 540 attcaaacac cgcctgatcc gcgccttgac caaaatcagc agggaaaggg aaaaacgtcg 600 gcaaaggcgc gaacagttaa tcggcaagat cattgtgcct ttccaataaa aggagaaaag 660 atggacatcg tatttgcggc agacgacaac tatgccgcct atctttgcgt tgcggcaaaa 720 agcgtggaag cggcccatcc cgatacggaa atcaggttcc acgtcctcga tgccggcatc 780 agtgaggcaa accgggcggc ggttgccgcc aatttgcggg gggggggggg taatatccgc 840 tttatagacg taaaccccga agatttcgcc ggcttcccct taaacatcag gcacatttcc 900 attacgactt atgcccgcct gaaattgggc gaatacattg ccgattgcga taaagtcctg 960 tatctggata tagacgtatt ggtcagggac agcctgacgc ccttatggga taccgatttg 1020 ggcgataact ggcttggcgc gtgcattgat ttatttgtcg aaaggcagga aggctacaaa 1080 caaaaaatcg gtatggcgga cggcgaatat tatttcaatg ccggcgtatt gctgatcaac 1140 ctgaaaaagt ggcggcggca cgatattttc aaaatgtcct gcgaatgggt ggaacaatac 1200 aaggacgtga tgcaatatca ggatcaggac attttgaacg ggctgtttaa aggcggggtg 1260 tgttatgcga acagccgttt caactttatg ccgaccaatt atgcctttat ggcgaactgg 1320 tttgcgtccc gccataccga cccgctttac cgcgaccgta ccaatacggt gatgcccgtc 1380 gccgtcagcc attattgcgg ctcggcaaag ccgtggcaca gggactgcac cgcgtggggt 1440 gcggaacgtt tcacagagtt gggcggcagc ctgacgaccg ttcccgaaga atggcgcggc 1500 aaacttgccg tcccgcaccg tatgttttcg acaaagcgta tgcttcaaag atggcgcaga 1560 aagctgtctg ccagattctt acgcaagatt tattgacggg gcaggccgtc tgaagccttc 1620 agacggcatc ggacgtgtcg gaaaggagaa acggattgca acctttagtc agcgtattga 1680 tttgcgccta caacgcagaa aaatatttcg cccaatcatt agccgccgtc gtgaatcaga 1740 cttggcgcaa cttggagatt ttgattgttg atgacggctc gacggacggc acgccctcca 1800 ttgcccggcg tttccaagaa caggacggca ggattaggat aatttccaat ccccgcaatt 1860 tgggctttat ggcctcttta aacatcgggc tggacgaatt ggtaaagtcg gggggggata 1920 tattgcgcgc accgatgccg acgatattgc cgcccccggc tggattgaaa aaatcgtggg 1980 cgagatggaa aaagacgcgg atattgccgc gatgggaacc tatttggaga ttttggcgga 2040 agaaaacaat aaaagcgtgc ttgccgccat tgcccgaaac ggcgaaattt ggaaaaaccc 2100 cctgacccat caggaaatca cgtctgcctt ccccctccgc aaccccatac acaacaacac 2160 gatgattatg cggcgcagcg tcattgacgg cggtttgcgg ttcgatcccg cctatatcca 2220 cgccgaagac tataagtttt ggtacgaagc cggcaaattg ggcaggctgg cgaattaccc 2280 cgaagccttg gtcaaatacc gtttccatca agaccagact tcttccaaac acaacctgca 2340 acagcgtaag acggcgtgga aaatcaaaga agaaatcagg gcggggtatt ggaaggcggc 2400 aggcataacc gtcgggtcgg actgcctgaa ttacgggctt ttgaaatcaa cggcatatgc 2460 gttgcacgaa aaagccttgt ccggacagga tatcggatac ctccgcctgt tcctgtacga 2520 atatttcttg tcgttggaaa agtattcttt gaccgattta ctggattttc tgacagaccg 2580 cgtgatgagg aagctgtttg ccgcaccgca atataggaaa atcctgaaaa aaatgttacg 2640 cccttggaaa taccggggct attgaaaccg aacagggaaa atcatgcaaa accacgttat 2700 cagcttagct tccgccgcag aacgcagggc gcacattgcc gataccttcg gcgcgcacga 2760 cattccgttt cagtttttcg acgcactgat gccgtctgaa gcactggagc aggcaatggc 2820 ggaactcgta cccggtttgt cggcgcaccc ctatttgagc ggagtggaaa aagcctgctt 2880 tatgagccac gccgtattgt ggaaacaggc attggatgaa ggtctgccct atgttgccgt 2940 atttgaggat gatgtcctgc ttggcaaaga cgcagaaaag ttccttgccg aagatacttg 3000 gttggaagag cgttttgata aggattctgc ctttatcgtt cgtttggaaa cgatgtttgc 3060 gaaagttatt gtcagaccgg ataaagtcct gaattatgag aaccggtcat ttcctttgct 3120 ggagagcgaa cattggggga cggctggcta tatcatttcg cgtgaggcga tgcggttttt 3180 cttggaaagg tttgccgttt tgccggcaga gcggattaaa gcggtagatt ggatgatgtt 3240 tacttatttc tttgataagg aggggatgcc tgtttatcag gttaatcccg ccttatgtac 3300 ccaagaattg cattatgcca agttcctcag taaaaacagt atgttgggta gcgatttgga 3360 aaaagatagg gaacaagaaa gaagacaccg ccgttcgttg aaggtgatgt ttgacttgaa 3420 gcgtgctttg ggtaaattcg gtagggaaaa gaagaaaaga atggagcgtc aaaggcaggc 3480 ggagcttgag aaagcttacg gcaggcgggt catatcgttc aaatagtttg tgtaaaatat 3540 agcggattaa aattagaaat ggatacactg tcattcccgc gcaggcggga atctagtccg 3600 ttcggtttcg cttgttttaa gtttcgggta acttccactt cgtcattccc gcgcaggcgg 3660 gaatccagtc cgttgagttt cagtcatttc cgataaatca ccgcaacgtt aa 3712 // |
|