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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   U59690; SV 1; linear; mRNA; STD; INV; 1364 BP.
XX
AC   U59690;
XX
DT   07-JUL-1996 (Rel. 48, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 4)
XX
DE   Brugia pahangi microfilarial chitinase mRNA, partial cds.
XX
KW   .
XX
OS   Brugia pahangi
OC   Eukaryota; Metazoa; Nematoda; Chromadorea; Spirurida; Filarioidea;
OC   Onchocercidae; Brugia.
XX
RN   [1]
RP   1-1364
RX   DOI; 10.1073/pnas.89.5.1548
RX   PUBMED; 1542646.
RA   Fuhrman J.A., Lane W.S., Smith R.F., Piessens W.F., Perler F.B.;
RT   "Transmission-blocking antibodies recognize microfilarial chitinase in
RT   brugian lymphatic filariasis";
RL   Proc. Natl. Acad. Sci. U.S.A. 89(5):1548-1552(1992).
XX
RN   [2]
RP   1-1364
RX   DOI; 10.1016/0166-6851(96)02671-0
RX   PUBMED; 8892292.
RA   Arnold K., Venegas A., Houseweart C., Fuhrman J.A.;
RT   "Discrete transcripts encode multiple chitinase isoforms in Brugian
RT   microfilariae";
RL   Mol. Biochem. Parasitol. 80(2):149-158(1996).
XX
RN   [3]
RP   1-1364
RA   Arnold K., Venegas A., Houseweart C., Fuhrman J.A.;
RT   ;
RL   Submitted (31-MAY-1996) to the EMBL/GenBank/DDBJ databases.
RL   Biology, Tufts University, 017 Dana Labs, Medford, MA 02155, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1364
FT                   /organism="Brugia pahangi"
FT                   /mol_type="mRNA"
FT                   /db_xref="taxon:6280"
FT   CDS             <1..>1364
FT                   /codon_start=3
FT                   /product="microfilarial chitinase"
FT                   /EC_number="3.2.1.14"
FT                   /note="Method: conceptual translation supplied by author;
FT                   RT-PCR generated partial cDNA cloned into pGEM-T; differs
FT                   from B.malayi microfilarial chitinase p70 (M73689) in
FT                   containing 4, instead of 3, ser/thr-rich repeats"
FT                   /db_xref="GOA:Q27457"
FT                   /db_xref="HSSP:1LG2"
FT                   /db_xref="InterPro:IPR001223"
FT                   /db_xref="InterPro:IPR001579"
FT                   /db_xref="InterPro:IPR002557"
FT                   /db_xref="InterPro:IPR011583"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="InterPro:IPR017853"
FT                   /db_xref="UniProtKB/TrEMBL:Q27457"
FT                   /protein_id="AAC47324.1"
FT                   /translation="LGDSKAFEWNDEDTPEKKGMYSAVTKLRETNPGLKVLLSYGGYNF
FT                   GSAIFTGIAKSAQKTERFIKSAIAFLRKNNFDGFDLDWEYPVGVAEEHAKLVEAMKTAF
FT                   VEEAKTSGKQRLLLTAAVSAGKGTIDGSYNVESLGKNFDLLFLMSYDLHGSWEKNVDLH
FT                   GKLHPTKGEVSGIGIFNTEFAADYWASKGMPKQKIIIGIPMYAQGWTLDNPSETAIGAA
FT                   ASRPSSASKTNPAGGTASYWEICKYLKEGGKETIHQEGVGAYMVKGDQWYGYDNEETIR
FT                   IKMKWLKEKGYGGAFIWALDFDDFTGKSCGKGPYPLLNAISSELEGESENPEITTEEPS
FT                   ITETEAYDTDETEETSETEAYDTDETEETSETEAYDTDETEETSETEATTYDTDETEGQ
FT                   ECPERDGLFPHPTDCHLFIHCANNIAHVKQCPATTFFNDAIKVCDHMTNAPDTCI"
XX
SQ   Sequence 1364 BP; 457 A; 247 C; 324 G; 336 T; 0 other;
     aattaggtga ttcaaaagct tttgaatgga acgatgaaga tactccagag aagaaaggaa        60
     tgtactcagc tgtaacgaaa ctgagagaaa ccaacccagg actgaaagtc cttctttcct       120
     atggtggcta caacttcgga tcagcaattt tcactggaat agcaaagtcg gcgcaaaaaa       180
     cggaacgttt tattaaatca gctatagcat ttctccgtaa gaataatttt gatggattcg       240
     atttggattg ggaatatcca gtcggtgtag ctgaggaaca cgctaaactt gttgaggcaa       300
     tgaaaacagc atttgtggaa gaagccaaaa catctggtaa gcaacgatta cttttaacgg       360
     ctgctgtatc agccgggaaa ggaactattg acggaagtta caatgtggag tctctcggaa       420
     aaaatttcga tctcctattt ctaatgtcat acgatttaca cggtagttgg gagaagaacg       480
     tcgatttaca cggaaaattg catccaacaa agggagaagt ttccggaatt ggcatattta       540
     atactgaatt tgctgcggac tattgggcaa gtaagggtat gccgaaacag aaaattatca       600
     ttggaattcc gatgtacgct cagggatgga cattagataa tccttcggaa acagcgattg       660
     gagcagcggc tagtcgtccg tcgtcagcat cgaaaacaaa tcctgctggt ggtactgcat       720
     cttactggga gatatgcaaa tatctgaaag aaggtggcaa ggaaacgatt catcaagaag       780
     gtgtcggggc atacatggta aaaggagacc aatggtatgg ttatgataac gaggaaacta       840
     tcagaattaa aatgaaatgg cttaaagaga aaggatatgg tggtgccttc atatgggctc       900
     ttgatttcga tgatttcacg ggtaaaagct gtggcaaagg cccttaccca ttgttaaatg       960
     ctatcagcag tgagcttgaa ggcgagtcag aaaaccctga aataactacg gaagaaccaa      1020
     gcattacaga aactgaagcg tatgatactg atgaaactga agaaacttcc gaaactgaag      1080
     cgtatgatac tgatgaaact gaagaaactt ccgaaactga agcatatgat actgatgaaa      1140
     ctgaagaaac ttccgaaact gaagcgacaa cgtatgatac tgatgaaact gaaggtcagg      1200
     aatgtccaga acgtgacggt ttgttcccgc atcctactga ttgccatttg tttattcact      1260
     gcgcaaataa cattgcacat gtgaagcaat gtccagcgac tactttcttc aatgacgcaa      1320
     tcaaagtttg cgaccacatg acgaatgcgc cggatacatg catc                       1364
//
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