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EBI DbfetchID U58133; SV 1; linear; genomic DNA; STD; FUN; 5015 BP. XX AC U58133; XX DT 16-JUN-1996 (Rel. 48, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 5) XX DE Candida albicans alpha-aminoadipate reductase large subunit (LYS2) gene, DE complete cds. XX KW . XX OS Candida albicans OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. XX RN [1] RP 1-5015 RX DOI; 10.1007/s002940050336 RX PUBMED; 9560434. RA Suvarna K., Seah L., Bhattacherjee V., Bhattacharjee J.K.; RT "Molecular analysis of the LYS2 gene of Candida albicans: homology to RT peptide antibiotic synthetases and the regulation of the alpha-aminoadipate RT reductase"; RL Curr. Genet. 33(4):268-275(1998). XX RN [2] RP 1-5015 RA Suvarna K.C., Bhattacharjee J.K.; RT ; RL Submitted (10-MAY-1996) to the EMBL/GenBank/DDBJ databases. RL Microbiology, Miami University, 32 Pearson Hall, Oxford, OH 45056, USA XX RN [3] RC Nucleotide and amino acid sequence updated by submitter RP 1-5015 RA Suvarna K.C.; RT ; RL Submitted (10-FEB-1998) to the EMBL/GenBank/DDBJ databases. RL Internal Medicine, Yale University/VAMC, 950 Campbell Avenue, Bldg I-111, RL West Haven, CT 06516, USA XX CC On Feb 10, 1998 this sequence version replaced gi:1377860. XX FH Key Location/Qualifiers FH FT source 1..5015 FT /organism="Candida albicans" FT /chromosome="1" FT /strain="B792" FT /mol_type="genomic DNA" FT /clone="pCALYS2" FT /db_xref="taxon:5476" FT CDS 660..4835 FT /codon_start=1 FT /transl_table=12 FT /gene="LYS2" FT /product="alpha-aminoadipate reductase large subunit" FT /function="lysine biosynthesis" FT /EC_number="1.2.1.31" FT /note="alpha-aminoadipate-semialdehyde dehydrogenase" FT /db_xref="GOA:Q12572" FT /db_xref="HSSP:1AMU" FT /db_xref="InterPro:IPR010080" FT /db_xref="UniProtKB/Swiss-Prot:Q12572" FT /protein_id="AAC02241.1" FT /translation="MTDFWLNYLDNPTLSVLPHDFLKPANNKSVEGTYTFNIDNGSTDF FT KFGLAVFAALVYRLTGDEDIVIATDESANTPEFIVRLNLTPELTFQELVSKITKEYENN FT ISQINYKALSEVSHRIKEAKGLDENPGLFRLSYQHAHSNQQLNTTVEGSIRDLAIYTDG FT TKFTIYYNALLYSHERVVICGEQFAQLTTVSGDTDTVIAEVFLITDFHKKNLPDPTIDL FT DWSGYRGAIQEIFMDNANKHPDRTCVVETVSFLESNSKTRNFSYHKLIKLLIVVGNYLK FT ETGIKKGDIVMIYAYRGVDLMIAVMGVLKAGATFSVIDPAYPPARQNIYLSVAKPKGLI FT GLEKAGTLDQLVVDYISNELDVVSTIPQLKVQDDGTLVGGKLEGADNDCLNDYQKFKDQ FT PAGVIVGPDSRPTLSFTSGSEGIPKGVLGRHYSLAYYFPWMAKRFRLSEKDKFTILSGI FT AHDPIQRDMFTPLFLGAQLLVPTADDIGTPGKLADWMAKYGATVTHLTLAMGQLLSAQA FT TTAIPSLHAFFVGDILTKRDCLRLQSLAENVFIVNMLWSLSQTQRSVSYFEIKSRKADP FT TYLKNLKAVMPAGTGMHNVQLLVVNRNDRSQTCGVGEVGEIYVRAAGLAEGYRGLPDLN FT AAKFITNWYVNPDKWIEQDEANKKSSETSERTWSVKPRDRMYRSGDLGRYFSDGNVECC FT GRADDQVKIRGFRIELGEIDTHLSQHPLVRENVTLVRRDKNEEPTLISYIVPKDSPELK FT TFFADVDFPLKKSNDPIVKGLVAYRELIKDIKGYLKKKLASYAIPTIIVPLVKLPLNPN FT GKVDKPKLPFPDTAQLAAVAKLSVSSHDAQAAEEENLTKLEEQIRDLWLDVLPNRPATI FT SKDDSFFDLGSHSILGTRIFTYEQKLNVEIPLVSFKGDQRRPRFPIGLSRYNYSRREQR FT CRRFLKAKTYTMRRSKELSKELSKSALLESYSSLKQLPSGSVNVFVTGATGFLGSFIVR FT DLLTARNKNLDIKVYAHVRASSKEAGLQRLRQTGITYGIWDENWAEKIEIVLGDLSKEK FT FGLDNSQWSDLTNSIDVLFTMVLCHWVYPYSQLRMLNVIGTINVFNMAGEVKLKFFSFV FT SSTSALDTDYFVNLSDELLAQGKNGISEADDLQGSAKGLGNGYGQSKWAAEYIIRRAGE FT RGLKGCITRPGYVAGFSKTGASNTDDFLLRMLKGSAELGLYPDITNNVNMVPVDHVARV FT VTATALNPPSSEELTVAHVTGHPRILFNNFLGCLKAYGYEINPADYPVWTSALEKFVIE FT ESKESALFPLLHFVLDNLPQDTKAPELDDSNAAKSLKQDSKYTGEDFSAGKGVDLDQTG FT VYISYLIKIGFLPKPTGTGEKKLPEVEISDESLKLISGGAGARGSAAK" XX SQ Sequence 5015 BP; 1623 A; 829 C; 1018 G; 1545 T; 0 other; ggatccgtgg ggaatccaag tgtggaatgg caatcaatgg atagagttca cagaattgtt 60 caaaagagac caattagaat tactagattc tgtattgaag atagtataga gctgaaaatt 120 atcgaattgc aggaaaagaa ggcgaacatg atccatgcaa ctattaacaa tgatgatgct 180 gctatcagta ggcttacacc cgatgatttg caattcttgt ttatgaatta aagtgggttt 240 gtagagatat tatttttttg tgtgtttata tttataagtt taaattgatc aatattttgg 300 atttggctgt gactaatcaa agaaagcggc ttttttttcc cataactgta agggcacgtc 360 ttcctcctcc actaccaagt gactcattag aggcgataaa ttaaattaga aggatgcgaa 420 aagttttttc ttgtactgtt ttgcacgact tccaattaac aaggaagcgt taccggtagc 480 aacagcgaaa ctgcgtttcg tggagtcatt gaaagaaaaa aagaaatggg tacaaattct 540 atatatatta attagttgaa aattttcact acaatcttct attctttttt aatttttgtt 600 tttaatttta ttttctttat tcgaaataac tttaaggacc ttcaattaat tccacaacaa 660 tgactgactt ttggttgaat tatttggata atcctacatt atctgtgtta ccccatgatt 720 ttttaaaacc tgctaataat aaatccgtgg aaggtactta cacattcaac attgataatg 780 gtagtactga tttcaaattt ggcttggctg tatttgctgc attggtttac agattaaccg 840 gtgatgaaga tatagtaatt gccactgacg aatcggccaa cactccagaa tttattgtca 900 ggttaaactt gacaccagaa ttaactttcc aagagctcgt cagtaaaata accaaagagt 960 acgaaaacaa catttctcaa ataaactaca aagcattatc tgaggtttca catagaatta 1020 aagaggctaa agggttagat gaaaaccctg gattgttcag attgtcctat caacatgctc 1080 actctaatca acaattgaat accacagtcg agggatctat tcgtgattta gcgatctaca 1140 ccgatggaac aaaattcacc atttactaca atgccttatt atattcacac gaaagagttg 1200 tgatatgtgg agaacaattt gcacagttaa caactgtatc gggcgatacc gatactgtta 1260 tagctgaagt gtttttgatt accgacttcc acaaaaagaa tttgcctgat ccgacaatag 1320 atttagattg gtcaggttac agaggtgcta ttcaagagat ctttatggat aatgcaaata 1380 aacatcctga tagaacatgt gttgttgaaa ccgtttcatt cttggagtca aactcaaaaa 1440 ctcgtaactt ttcctaccac aaattaatca agcttctaat tgttgttggt aactacttga 1500 aagaaacagg aatcaaaaaa ggtgatattg ttatgatcta cgcttaccgt ggggtagatt 1560 taatgattgc tgttatgggt gttttaaaag ccggagcaac attttccgtc attgaccctg 1620 cttaccctcc agcaagacag aatatttatc tttctgtggc aaaaccaaaa gggttaattg 1680 ggttagaaaa agccggtact ttggatcaat tagttgttga ttatattagt aacgaattag 1740 atgttgtttc tacgatccca caattgaaag ttcaagatga tggtacatta gtaggtggta 1800 aacttgaagg tgcagataac gattgcctta acgattatca aaaattcaaa gatcagccag 1860 ctggggtgat tgtgggtcct gattccaggc caactttatc attcacttct ggatcagaag 1920 gtattccaaa aggggtattg ggtcgtcatt attcattagc ctattatttc ccatggatgg 1980 ctaaaagatt tagattatcg gaaaaagaca aattcaccat attatcgggt attgcccatg 2040 accctattca aagagacatg tttactccgt tgtttttggg agctcaatta ttagtgccaa 2100 ctgctgatga cattggtact cctgggaaat tggctgactg gatggccaag tatggagcaa 2160 cagtgacaca cttaacatta gctatgggtc aattgttgag tgcccaagcc accactgcaa 2220 ttccaagctt acatgccttc tttgttggtg acattttaac aaagagagat tgtttaagat 2280 tacaaagttt agctgaaaat gtgtttattg ttaacatgct atggtcacta ctgcaaacac 2340 agagatcagt gtcatacttt gaaatcaaaa gtcgtaaagc agatcctaca tacttaaaaa 2400 acttgaaagc tgtgatgcct gcagggaccg gtatgcacaa cgttcaattg ttagtcgtta 2460 atagaaatga ccgctcgcaa acctgtggtg ttggggaagt tggtgaaatc tatgttaggg 2520 cagctggttt agccgaagga taccgtggat tgcctgattt aaatgctgct aagtttatta 2580 ccaattggta tgtcaaccca gacaaatgga tcgaacaaga tgaagctaac aaaaaatcca 2640 gtgaaacgct ggagagaaca tggctggtta aaccaagaga cagaatgtat agatctggtg 2700 atttgggtcg ttatttcctg gatggtaatg ttgaatgttg tggtagagca gatgaccaag 2760 tcaagattag aggtttcaga attgaattgg gtgaaattga tactcatttg tctcaacatc 2820 ctcttgtcag agaaaatgtc accttggtga gaagagacaa aaatgaggaa ccaacattga 2880 tttcttacat tgttccaaaa gattctccag aattgaaaac attctttgct gatgttgatt 2940 tcccactaaa gaagtccaat gatccaattg tcaagggatt agtcgcttac agagaattga 3000 ttaaagacat caaaggatac ttgaaaaaga agttggcatc ctacgctatt ccaacaatca 3060 ttgtaccatt agtgaaatta cctttgaatc ctaatggtaa agtagacaaa ccgaaattac 3120 catttccaga tactgctcag ttggcagcag tcgccaaatt aagcgtttct agtcatgatg 3180 cccaagctgc tgaagaagaa aacttgacca aattggaaga gcaaattaga gatttgtggt 3240 tagatgtgtt accaaaccgt ccagcaacaa tttccaaaga tgattcattc ttcgatttag 3300 gaagtcactc tattttgggt accagaatat ttacttacga acagaaatta aatgtggaaa 3360 tcccattggt gtcatttaaa ggtgatcaaa ggaggccaag atttccaatt ggcttatcaa 3420 ggtacaacta ttcaagaaga gaacaaagat gtcgtagatt cctcaaagcg aaaacctaca 3480 ctatgcgaag atccaaagaa ttatcaaaag aattatcaaa atcagcactt ttggaatcat 3540 attcatcttt gaaacagctt ccatctggat ctgttaacgt ttttgttact ggtgctacag 3600 ggttcttggg ttcttttatt gttcgtgact tgttgactgc acgtaacaaa aacttggata 3660 tcaaagtgta tgctcatgta agagcatctt ccaaggaagc tgggttacaa agattacgtc 3720 aaaccgggat cacttatggt atttgggatg aaaattgggc cgaaaagatt gaaattgtgt 3780 taggtgattt atcaaaagaa aaatttggat tggataattc tcaatggtca gatttgacta 3840 atagcattga tgtgttattc acaatggtcc tttgtcactg ggtatatcca tactctcagt 3900 tacgtatgct aaatgttatt ggtactatca atgttttcaa catggcaggt gaagtaaagc 3960 taaagttctt ttcatttgtt tcttcaacat ccgctttaga tactgattac tttgttaatt 4020 tatcggatga attattagct caaggtaaaa atggtatttc cgaagctgac gatttacaag 4080 gatcggctaa ggggctagga aacggatatg gacaatccaa atgggctgct gagtacatta 4140 taagacgtgc tggtgaacgt ggattgaaag gatgtatcac cagacctggt tatgttgctg 4200 ggttttccaa aactggtgct tccaatactg atgatttctt attgagaatg ttgaaaggat 4260 ctgctgaatt ggggttatat cctgatatca ctaataatgt caatatggtc cctgttgatc 4320 atgttgccag agttgttact gctactgcat taaacccacc aagtagtgaa gaattaactg 4380 ttgctcatgt gaccggtcat cctagaattc ttttcaacaa ctttttggga tgcttgaaag 4440 catatggata tgagataaac ccagcagact atccagtatg gaccagtgca ttggagaaat 4500 ttgttattga agaaagtaaa gaatcagcct tattcccact tttacatttt gtgttggata 4560 atttgccaca agacacaaag gctcccgagt tagacgactc taatgcagcc aaatcattaa 4620 aacaagattc caaatatacg ggagaagatt ttagtgctgg taaaggtgtg gatttggatc 4680 aaactggtgt ttacattagt tatttgatca agattggatt cttgcctaaa ccaactggta 4740 caggcgagaa gaaattgcct gaagttgaga ttagtgatga aagcttgaaa ttgattagtg 4800 gaggtgctgg tgcacgagga tcagctgcca aataagtaat acttcaaagt taaaatacca 4860 ggaaaggaga acttatgtct tagtcttagt tgtagtatat acacagatca atattgccta 4920 gactagaagt agactataag taaattatta atatgaaata acgatatttt taaattatca 4980 gagtagaaca agaactacca accaaacaat tacat 5015 // |
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