EBI Dbfetch

ID   U47011; SV 1; linear; genomic DNA; STD; HUM; 2267 BP.
XX
AC   U47011;
XX
DT   02-JUL-1996 (Rel. 48, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 6)
XX
DE   Human fibroblast growth factor 8 (FGF8) gene, exon 3 and complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-2267
RX   DOI; 10.1006/geno.1996.0349
RX   PUBMED; 8661131.
RA   Gemel J., Gorry M., Ehrlich G.D., MacArthur C.A.;
RT   "Structure and sequence of human FGF8";
RL   Genomics 35(1):253-257(1996).
XX
RN   [2]
RP   1-2267
RA   MacArthur C.A.;
RT   ;
RL   Submitted (24-JAN-1996) to the EMBL/GenBank/DDBJ databases.
RL   Craig A. MacArthur, Pediatrics, Washington University School of Medicine,
RL   One Children's Place, St. Louis, MO 63110, USA
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..2267
FT                   /organism="Homo sapiens"
FT                   /chromosome="10"
FT                   /map="10q24-25"
FT                   /mol_type="genomic DNA"
FT                   /sex="male"
FT                   /clone_lib="Human placenta genomic DNA in lambda Fix II
FT                   from Stratagene"
FT                   /clone="pXX 2.3"
FT                   /tissue_type="placenta"
FT                   /db_xref="taxon:9606"
FT   mRNA            join(U47009.1:<1..202,U47009.1:295..331,U47009.1:855..941,
FT                   U47009.1:1155..1335,U47010.1:395..501,446..736)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="form 8F"
FT   mRNA            join(U47009.1:<1..202,U47009.1:295..331,
FT                   U47009.1:1155..1335,U47010.1:395..501,446..736)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="form 8B"
FT   mRNA            join(U47009.1:<1..202,U47009.1:295..331,
FT                   U47009.1:1188..1335,U47010.1:395..501,446..736)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="form 8A"
FT   mRNA            join(U47009.1:<1..202,U47009.1:295..331,U47009.1:855..941,
FT                   U47009.1:1188..1335,U47010.1:395..501,446..736)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="form 8E"
FT   CDS             join(U47009.1:171..202,U47009.1:295..331,U47009.1:855..941,
FT                   U47009.1:1155..1335,U47010.1:395..501,446..736)
FT                   /codon_start=1
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="alternatively spliced form 8F; AIGF,
FT                   androgen-induced growth factor; similar to mouse FGF8,
FT                   variant 6, GenBank Accession Number U18673"
FT                   /db_xref="GDB:591889"
FT                   /db_xref="GOA:P55075"
FT                   /db_xref="HGNC:3686"
FT                   /db_xref="InterPro:IPR002348"
FT                   /db_xref="InterPro:IPR008996"
FT                   /db_xref="PDB:2FDB"
FT                   /db_xref="UniProtKB/Swiss-Prot:P55075"
FT                   /protein_id="AAC50782.1"
FT                   /translation="MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGRE
FT                   PQGVSQQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINA
FT                   MAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVL
FT                   ENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEF
FT                   LNYPPFTRSLRGSQRTWAPEPR"
FT   CDS             join(U47009.1:171..202,U47009.1:295..331,
FT                   U47009.1:1155..1335,U47010.1:395..501,446..736)
FT                   /codon_start=1
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="form 8B, major form expressed; AIGF,
FT                   androgen-induced growth factor; similar to mouse FGF8,
FT                   variant 1, GenBank Accession Numbers U18673 and D12482"
FT                   /db_xref="GDB:591889"
FT                   /db_xref="GOA:P55075"
FT                   /db_xref="HGNC:3686"
FT                   /db_xref="InterPro:IPR002348"
FT                   /db_xref="InterPro:IPR008996"
FT                   /db_xref="PDB:2FDB"
FT                   /db_xref="UniProtKB/Swiss-Prot:P55075"
FT                   /protein_id="AAC50785.1"
FT                   /translation="MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQ
FT                   LSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAET
FT                   GLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGS
FT                   KTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR"
FT   CDS             join(U47009.1:171..202,U47009.1:295..331,U47009.1:855..941,
FT                   U47009.1:1188..1335,U47010.1:395..501,446..736)
FT                   /codon_start=1
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="alternatively spliced form 8E; AIGF,
FT                   androgen-induced growth factor; similar to mouse FGF8,
FT                   variant 7, GenBank Accession Number U18673"
FT                   /db_xref="GDB:591889"
FT                   /db_xref="GOA:P55075"
FT                   /db_xref="HGNC:3686"
FT                   /db_xref="InterPro:IPR002348"
FT                   /db_xref="InterPro:IPR008996"
FT                   /db_xref="PDB:2FDB"
FT                   /db_xref="UniProtKB/Swiss-Prot:P55075"
FT                   /protein_id="AAC50784.1"
FT                   /translation="MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGRE
FT                   PQGVSQQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKL
FT                   IVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAK
FT                   YEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLR
FT                   GSQRTWAPEPR"
FT   CDS             join(U47009.1:171..202,U47009.1:295..331,
FT                   U47009.1:1188..1335,U47010.1:395..501,446..736)
FT                   /codon_start=1
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8 precursor"
FT                   /note="alternatively spliced form 8A; AIGF,
FT                   androgen-induced growth factor; similar to mouse FGF8,
FT                   variant 4, GenBank Accession Number U18673"
FT                   /db_xref="GDB:591889"
FT                   /db_xref="GOA:P55075"
FT                   /db_xref="HGNC:3686"
FT                   /db_xref="InterPro:IPR002348"
FT                   /db_xref="InterPro:IPR008996"
FT                   /db_xref="PDB:2FDB"
FT                   /db_xref="UniProtKB/Swiss-Prot:P55075"
FT                   /protein_id="AAC50783.1"
FT                   /translation="MGSPRSALSCLLLHLLVLCLQAQHVREQSLVTDQLSRRLIRTYQL
FT                   YSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK
FT                   LIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHF
FT                   MKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR"
FT   mat_peptide     join(U47009.1:329..331,U47009.1:855..941,
FT                   U47009.1:1188..1335,U47010.1:395..501,446..733)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8"
FT                   /note="form 8E"
FT   mat_peptide     join(U47009.1:329..331,U47009.1:1155..1335,
FT                   U47010.1:395..501,446..733)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8"
FT                   /note="form 8B"
FT   mat_peptide     join(U47009.1:329..331,U47009.1:1188..1335,
FT                   U47010.1:395..501,446..733)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8"
FT                   /note="form 8A"
FT   mat_peptide     join(U47009.1:329..331,U47009.1:855..941,
FT                   U47009.1:1155..1335,U47010.1:395..501,446..733)
FT                   /gene="FGF8"
FT                   /product="fibroblast growth factor 8"
FT                   /note="form 8F"
FT   intron          <1..443
FT                   /gene="FGF8"
FT                   /number=2
FT   exon            446..736
FT                   /gene="FGF8"
FT                   /number=3
FT                   /note="similar to AIGF, exon 5, GenBank Accession Number
FT                   S78466"
XX
SQ   Sequence 2267 BP; 443 A; 594 C; 748 G; 482 T; 0 other;
     ctcgagctcc ccacttcctg ggcttctggg gctggggtct tagcatcttc tcccaggcct        60
     cccctccccc ataggtggct gccctggggc cagggaaccg aagtcctggg ggggtgagag       120
     gggcaggtgg ggagacgggt ggccagactg gtgggcagga ggccagagca ggccaggctc       180
     tgggcccctc tctctgtctt tctgcgttgg ggcccagccc tccgtagaca accatgtgtc       240
     actgctgcct gggaaggaca ggaagttgcc gggtgggctg cgagttgtga gggattagag       300
     agcgggtgcc caggcagggg ggtggggctg cggctcctgc ccacctcgcc atctgctggg       360
     gtgcccacct gctgtctggg gccgctcgcc ctctgcctct gctggggggg ctctgtaacg       420
     tggtgtctgg ctcccctacc tgcagagcaa cggcaaaggc aaggactgcg tcttcacgga       480
     gattgtgctg gagaacaact acacagcgct gcagaatgcc aagtacgagg gctggtacat       540
     ggccttcacc cgcaagggcc ggccccgcaa gggctccaag acgcggcagc accagcgtga       600
     ggtccacttc atgaagcggc tgccccgggg ccaccacacc accgagcaga gcctgcgctt       660
     cgagttcctc aactacccgc ccttcacgcg cagcctgcgc ggcagccaga ggacttgggc       720
     ccccgagccc cgatagtgct gcctggccct ccccacaatg ccagaccgca gagaggctca       780
     tcctgtaggg cacccaaaac tcaagcaaga tgagctgtgc gctgctctgc aggctgggga       840
     ggtgctgggg gagccctggg ttccggttgt tgatattgtt tgctgttggg tttttgctgt       900
     tttttttttt tttttttttt ttaaaacaaa agagaggctc tatttttgta ttccacttgg       960
     ctgtggtgtc tgtcttctta actctcagaa agctccatta gtggcctaga ctgggattcc      1020
     ggctgggggt ttgcgggggt ggggggcttt ctctagcctg tgctgctgag gccccagtac      1080
     ctccagggcc agttggctgg gcagccaggg actccactgc acccccaggt ggggcaggga      1140
     ggaaaggact gtgacatagg gcagtcctct tagaagtggg tatcagactg gtggctatta      1200
     aatgattgaa atatttattt aacttgcata ttaaaaatgt gtgctggaga gtgagtcctg      1260
     ccggggtcag cccctccctc caaccttgcc ccagctggtg ggcggctggg agacgcagat      1320
     gaccaggtgc cagctctgac cacagcctcc ctccagccta aagacacctg cctgtcaacc      1380
     atccccatca ctgtcacttg aggggttttc ctgcaaggac agaagcaggg aaaggggcaa      1440
     gaagaggctc ttagctagtc cttggagctc tcagatgtgt acctcctagc actttacaga      1500
     ggtcattgct aacacttccc caggccacct cagggccaga aataatggat gtgctagggc      1560
     tagagctgta atcatggatt taatcctctt aaaaagtgct tctctgagtg cctaggtcca      1620
     tgtgggagac aggttggaga ttccagaact tgctctttct gagactcagg ctccagaaaa      1680
     tgaaagaaaa gagcagctgc cagggtccaa ggtgggggca tattggaggg ggaccaccaa      1740
     gactggtgtt gacaatggtg atgtgggaca agtgttaacc ttgggtgata tggtgagata      1800
     gctgtgggca gaaagcactg agctgaggtg cggcgaggag cctggggaac tgtcttccag      1860
     gaagaggctg cccacctcgg aggatgggct ggcgggagag gagctgggca ccggatggca      1920
     ccagaaggga agctcatagg cctagcgcag aactaaaggc agtcatagcc ttggggagaa      1980
     gcaggaggcc gtatgtggag ggagggaggg ctgctgtggg agtggtggag caggtcatgg      2040
     tgtgggcaga gaagggaatg ggcaagggtg caggtgtgtg tttgcgtgtg gactggtgag      2100
     actggtgtcc tgccacaccg agggagagcc caggccccac ggcagtttcc tgagtgcaga      2160
     gctggcccag gcttcatcgc tgaggcctcc cattagggct gctcctgctt ccttccttgt      2220
     ggatgccctg ggctggtccc acagcccagc tactgagcca gtctaga                    2267
//