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EBI DbfetchID U40830; SV 1; linear; genomic DNA; STD; PRO; 15250 BP. XX AC U40830; XX DT 26-APR-1996 (Rel. 47, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 2) XX DE Streptococcus thermophilus DeoD gene, partial cds and EpsA, EpsB, EpsC, DE EpsD, EpsE, EpsF, EpsG, EpsH, EpsI, EpsJ, EpsK, EpsL, EpsM, Orf14.9 protein DE genes, complete cds. XX KW . XX OS Streptococcus thermophilus OC Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus. XX RN [1] RP 1-15250 RX PUBMED; 8626297. RA Stingele F., Neeser J.R., Mollet B.; RT "Identification and characterization of the eps (Exopolysaccharide) gene RT cluster from Streptococcus thermophilus Sfi6"; RL J. Bacteriol. 178(6):1680-1690(1996). XX RN [2] RP 1-15250 RA Stingele F.; RT ; RL Thesis (1996), Department of Microbiology, Technical University Munich XX RN [3] RP 1-15250 RA Stingele F.; RT ; RL Submitted (17-NOV-1995) to the EMBL/GenBank/DDBJ databases. RL Francesca Stingele, Nestec Ltd. Research Center, PO Box 44, 1000 Lausanne RL 26, Vers-chez-les Blanc, Switzerland XX CC NCBI gi: 1276872 XX FH Key Location/Qualifiers FH FT source 1..15250 FT /organism="Streptococcus thermophilus" FT /strain="Sfi6" FT /mol_type="genomic DNA" FT /db_xref="taxon:1308" FT CDS <1..651 FT /codon_start=1 FT /transl_table=11 FT /gene="deoD" FT /product="DeoD" FT /note="similar to E. coli purine phosphorylase; NCBI gi: FT 1276873" FT /db_xref="GOA:Q56037" FT /db_xref="InterPro:IPR000845" FT /db_xref="InterPro:IPR004402" FT /db_xref="InterPro:IPR018016" FT /db_xref="InterPro:IPR018017" FT /db_xref="UniProtKB/Swiss-Prot:Q56037" FT /protein_id="AAC44007.1" FT /translation="DPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGERISVMGTGMG FT MPSISIYARELIVDYGVKKLIRVGTAGSLNENVHVRELVLAQAAATNSNIIRNDWPQYD FT FPQIASFNLLDKAYHIAKNFGMTTHVGNVLSSDEKYSNYFEKNIELGKWGVKAVEMEAA FT ALYYLAAQHQVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAD" FT terminator 880..900 FT /gene="deoD" FT -35_signal 922..927 FT /gene="epsA" FT -10_signal 945..950 FT /gene="epsA" FT CDS 1000..2454 FT /codon_start=1 FT /transl_table=11 FT /gene="epsA" FT /product="EpsA" FT /function="exopolysaccharide regulation" FT /note="Method: conceptual translation supplied by author; FT NCBI gi: 1276874" FT /db_xref="GOA:Q56038" FT /db_xref="InterPro:IPR004190" FT /db_xref="InterPro:IPR004474" FT /db_xref="UniProtKB/TrEMBL:Q56038" FT /protein_id="AAC44008.1" FT /translation="MSSRTNRKQKHTSNGSWGMVNVGLTILYAILALVLLFTMFNYNFL FT SFRFLNIIITIGLLVVLAISIFLQKTKKLPLVTTVVLVIFSLVSLVGIFGFKQMIDITN FT RMNQTAAFSEVEMSIVVPKESDIKDVSQLTSVQAPTKVDKNNIEILMSALKKDKKVDVK FT VDDVASYQEAYDNLKSGKSKAMVLSGSYASLLESVDSNYASNLKTIYTYKIKKKNSNSA FT NQVDSRVFNIYISGIDTYGPISTVSRSDVNIIMTVNMNTHKILLTTTPRDAYVKIPGGG FT ADQYDKLTHAGIYGVETSEQTLEDLYGIKLDYYARINFTSFLKLIDQLGGVTVHNDQAF FT TQEKFDFPVGDIQMNSEQALGFVRERYNLDGGDNDRGKNQEKVISAILNKLASLKSVSN FT FTSIVNNLQDSVQTNMSLNTINALANTQLESGSKFTVTSQAVTGTGSTGQLISYAMPNS FT SLYMMKLDNSSVESASQAIKKLMEEK" FT CDS 2455..3186 FT /codon_start=1 FT /transl_table=11 FT /gene="epsB" FT /product="EpsB" FT /note="Method: conceptual translation supplied by author; FT NCBI gi: 1276875" FT /db_xref="GOA:Q56039" FT /db_xref="InterPro:IPR004013" FT /db_xref="InterPro:IPR016667" FT /db_xref="UniProtKB/TrEMBL:Q56039" FT /protein_id="AAC44009.1" FT /translation="MIDVHSHIVFDVDDGPETLEESLDLIGESYAQGVRKIVSTSHRRK FT GMFETPEDKIFANFKKVKAEAEALYPDLTIYYGGELYYTSDIVEKLEKNLIPRMHNTQF FT ALIEFSARTSWKEIHSGLSNVLRAGVTPIVAHIERYDALEENADRVREIINMGCYTQVN FT SSHVLKPKLFGDKDKVRKKRVRFFLEKNLVHMVASDMHNLGPRPPFMKDAYEIVKKNYG FT SKRAKNLFIENPKTLLENQYL" FT CDS 3195..3887 FT /codon_start=1 FT /transl_table=11 FT /gene="epsC" FT /product="EpsC" FT /function="chain length determinator and exporter" FT /note="Method: conceptual translation supplied by author; FT NCBI gi: 1276876" FT /db_xref="GOA:Q56040" FT /db_xref="InterPro:IPR003856" FT /db_xref="InterPro:IPR005701" FT /db_xref="UniProtKB/TrEMBL:Q56040" FT /protein_id="AAC44010.1" FT /translation="MNQDNTKSDEIDVLALLHKLWTKKLLILFTAFYFAVFSFLGTYFF FT IQPTYTSTTRIYVVNQATDNKNLSAQDLQAGTYLANDYKEIIASNDVLSEVIKDEKLNL FT SEAELSKMVSVNIPTDTRLISISVNAKTGQDAQTLANKVREVASKKIKKVTKVEDVTTL FT EEAKLPESPSSPNIKLNVLLGAVLGGFLAVVGVLVREILDDRVRRPEDVEDALGMTLLG FT IVPDTDKI" FT CDS 3897..4646 FT /codon_start=1 FT /transl_table=11 FT /gene="epsD" FT /product="EpsD" FT /function="chain length determinator and exporter" FT /db_xref="GOA:Q56041" FT /db_xref="InterPro:IPR005702" FT /db_xref="UniProtKB/TrEMBL:Q56041" FT /protein_id="AAC44011.1" FT /translation="MPLLKLVKSKVDFAKKTEEYYNAIRTNIQFSGAQMKVIAISSVEA FT GEGKSMISVNLAISFASVGLRTLLIDAETRNSVLSGTFKSNEPYKGLSNFLSGNADLNE FT TICQTDISGLDVIASGPVPPNPTSLLQNDNFRHLMEVARSCYDYVIIDTPPVGLVIDAV FT IIAHQADASLLVTEAGKIKRRFVTKAVEQLVESGSQFLGVVLNKVDMTVDKYGFYGSYG FT SYGEYGKKSDQKEGHSRAHRRRKVGWN" FT CDS 4699..5382 FT /codon_start=1 FT /transl_table=11 FT /gene="epsE" FT /product="EpsE" FT /db_xref="GOA:Q56042" FT /db_xref="InterPro:IPR003362" FT /db_xref="UniProtKB/TrEMBL:Q56042" FT /protein_id="AAC44012.1" FT /translation="MSQAKEEISDVMTYSELTSHKPKIIYSLIKRIGDILVSSIGLIIL FT IPLFLIVALIMKCSEPTAPIFFSHIRNGKNGKKFKMYKFRTMCQDAESILMKDTELFAK FT FKANGYKLETHEDPRITKIGGILRKTSIDELPQLINVFLGQMSLVGPRPLPDREIIEYG FT DNQEKFLSVKPGMTGWWQVSGRSTIGYPERCHLELYYVEKCCFTFDVLILLKTIGIVLK FT RVGAR" FT CDS 5546..6505 FT /codon_start=1 FT /transl_table=11 FT /gene="epsF" FT /product="EpsF" FT /note="similar to glycosyltransferase; Method: conceptual FT translation supplied by author; NCBI gi: 1276879" FT /db_xref="GOA:Q56043" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q56043" FT /protein_id="AAC44013.1" FT /translation="MNEQVTFILCDFLVREIKPKYDLLAYQFISKKIKEIKPDIVHCHS FT SKAGVIGRLAAKRRGVKKIFYTPHAYSFLAPEFSGKKKFLFVQIEKFLSRFATTKIFCV FT SIAEMQAALEVNLDKTDKFQVIYNGLPEIDLPSKETIRAQLGLEKAAVVIGNNAKMSEQ FT KNPMFFMEIARKMIRQNANWHFVWVGDGQLMPLFQSFIKQNGLEGNIHLLGERPDSEIV FT VTAYDIFLTTSQYEGLPYAPIEAMRAGVPILATKVVGNSELVIEGKNGYLIDLEWSKSV FT EEKLYKAAKIDAQMIKADFRQRFAIDQILKQIETIYLA" FT CDS 7073..8191 FT /codon_start=1 FT /transl_table=11 FT /gene="epsG" FT /product="EpsG" FT /note="similar to glycosyltransferase; Method: conceptual FT translation supplied by author; NCBI gi: 1276880" FT /db_xref="GOA:Q56044" FT /db_xref="InterPro:IPR001296" FT /db_xref="UniProtKB/TrEMBL:Q56044" FT /protein_id="AAC44014.1" FT /translation="MKKISILHFSQVSGGGVEKYIKLFLKYSDVTKFNNYLVAPNLENY FT DEFNGYLKMSVNFNMEQTFSPLKIFKNVFFIRSVLKKINPDIVYLHSTFAGVVGRIASI FT GLPTKVVYNPHGWSFKMDNSYLKKLIFKLIEFSLSFLTDKFILISESEYILANHISFNK FT SKFSLINNGVEVITGDSRNEIEEIFPNEDFIIGMVGRLSPPKEFFFFIDFAKKILQIRN FT DTNFIIVGDGELRSEIERMILDNGLGDKIYITGWVDNPRNYIEKFDQAILFSRWEGLSL FT TIAEYMSQKKTILATNIGGINDLITDGETGMLIEVGDLNSAVSKSFELRNNKEVSNQLA FT NNAYNKVVEQFSIEKQMAEIESLFIEMCNNEK" FT CDS 8384..8863 FT /codon_start=1 FT /transl_table=11 FT /gene="epsH" FT /product="EpsH" FT /note="similar to acetyltransferase/NodL-LacA-CysE family; FT Method: conceptual translation supplied by author; NCBI FT gi: 1276881" FT /db_xref="GOA:Q56045" FT /db_xref="HSSP:1KRR" FT /db_xref="InterPro:IPR001451" FT /db_xref="InterPro:IPR011004" FT /db_xref="InterPro:IPR018357" FT /db_xref="UniProtKB/TrEMBL:Q56045" FT /protein_id="AAC44015.1" FT /translation="MLILKLKFHLKSLFLKWIYRLLYLKKFQFGARLTFRDGFHLLIEK FT SGKVIIGNHVFFNNFCSINAMLSVTIGDDCIFGENVKIYDHNHCYQNKSQPISKQGFST FT AAIQIGRNCWIGSQVTILKGVTIGDNSIIGAGVVVYQDVPENSIVLSNGEIRKRG" FT CDS 8869..9843 FT /codon_start=1 FT /transl_table=11 FT /gene="epsI" FT /product="EpsI" FT /note="similar to glycosyltransferase; Method: conceptual FT translation supplied by author; NCBI gi: 1276882" FT /db_xref="GOA:Q56046" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q56046" FT /protein_id="AAC44016.1" FT /translation="MYLKSLISIVIPVYNVEKYLEKCLQSVQNQTYNNFEVILVNDGST FT DSSLSICEKFVNQDKRFSVFSKENGGMSSARNFGIKKAKGSFITFVDSDDYIVKDYLSH FT LVAGIKSETSIVCSKFFLVDEKGSLLTKKEAPKKKSEVVSIEESIKILLLQQNGYDLAV FT WGKLYPVSFFETISFPEGKLYEDMGTTYKLLKLASEVVFLDAYDYAYVQRPNSIMNSSF FT NLKKLDIIEMVHEMENDILAQFPNLALYVKNRAFAAEVKIFLEIPKEKEFEQAQKQLWH FT DIKKNRKAPFMTKGARLKNRLGASLSFLGKSLFLTIGKQLVDR" FT CDS 9933..11015 FT /codon_start=1 FT /transl_table=11 FT /gene="epsJ" FT /product="EpsJ" FT /note="similar to O-antigen polymerase of FT Enterobacteriaceae; NCBI gi: 1276883" FT /db_xref="UniProtKB/TrEMBL:Q56047" FT /protein_id="AAC44017.1" FT /translation="MVIYFLLFPMIAMIYLMTLLLRQKAQIQKTIFCVLTFGTLGFISA FT SRASSVGTDVTLYENIFKSINYGISAENNWGYVIYNKLIGSVFGYTGHEITAANSVLIT FT ILIGIFIWKVAEHYFVATFLYISLFYYATSFNISRQFIAMGLVLVAISFALDKKVMPWF FT ILTVLATLFHATAIVAFPVYWLTKVHWDVKKTLSIFPITIFASFIFDAILNIFVRFFPH FT YEMYITGTQFNISDQGQGRVVLVKIFILLILFTLFLFYKKSYALISECHQSLIALTTVG FT LSIGIVFYNNILLNRIEMFYSILSIVFIPIAIDYISLKFKQKDAVRLMLTIGILLITLV FT PYYIQVSGNYSGILPYVIQQ" FT CDS 11040..11990 FT /codon_start=1 FT /transl_table=11 FT /gene="epsK" FT /product="EpsK" FT /function="capsule synthesis" FT /note="similar to LipB of Neisseria meningitidis; Method: FT conceptual translation supplied by author; NCBI gi: FT 1276884" FT /db_xref="GOA:Q56048" FT /db_xref="InterPro:IPR003406" FT /db_xref="UniProtKB/TrEMBL:Q56048" FT /protein_id="AAC44018.1" FT /translation="MEDRKKQVILILSHRNTLALKSTIELLDSQYFDFFLHIDKKSRIQ FT DFFYLKKITKFSTIHFSERKNVHWGGFSMVEAMFALLECARDTGEYSYFHFLSGDDMPI FT KDNEIVFNFFENSYPKNFIDILDFENVNKNSYFYEPPEMIEERVKYYYPHMDILNRKGT FT NFIGKKLIYLQKLLKVNRLKNREIEIFKGHQWCSLTNQFVDILLDKEERRVGKSYFSSS FT LIPDECYFQTFAMIKKVEIYQQKNMSARLIDWTRGKPYIWRQDDFFEIMNDKDSMFSRK FT FDENVDRKIIEEIYIKIRGRSTDEANKIKDKRFTK" FT -35_signal 11884..11889 FT /gene="epsK" FT /note="EpsL" FT -10_signal 11903..11908 FT /gene="epsL" FT CDS 11950..12873 FT /codon_start=1 FT /transl_table=11 FT /gene="epsL" FT /product="EpsL" FT /note="Method: conceptual translation supplied by author; FT NCBI gi: 1276885" FT /db_xref="GOA:Q56049" FT /db_xref="InterPro:IPR007345" FT /db_xref="UniProtKB/TrEMBL:Q56049" FT /protein_id="AAC44019.1" FT /translation="MKQIKSKIRDLQNNFTYVFGKKTFLGRGEAIIIDEPEHGNLGDQA FT IAFAENQFLVNHVSVRDVEHLIESKTISEIKSIKKNIGKKELVFFHGGGNFGTLYLKYE FT RIRRLAVSKLPFNKMILFPQSISFEDSRFGQKQLNKSKKIYSQNTNFILTAREPKSYGL FT MKKCFPYNKVILTPDIVLSFKFEVTISDTHIGKEKDSVITYENRQHYLEIKWDEIAQHE FT VALTDRLHGMIFSYITGTPCVVLANNNHKIEGTYKHWLNEVNYIRFIENPTVENILDAI FT NDLKQIEPHYIDLSDKFQPLIDAIKG" FT CDS 12881..14302 FT /codon_start=1 FT /transl_table=11 FT /gene="epsM" FT /product="EpsM" FT /note="Method: conceptual translation supplied by author; FT NCBI gi: 1276886" FT /db_xref="GOA:Q56050" FT /db_xref="InterPro:IPR002797" FT /db_xref="UniProtKB/TrEMBL:Q56050" FT /protein_id="AAC44020.1" FT /translation="MNKYKKLLSNSLVFTIGNLGSKLLVFLLVPLYTYAMTPQEYGMAD FT LYQTTANLLLPLITMNVFDATLRFAMEKSMTKESVLTNSLVVWCFSAVFTCLGACIIYA FT LNLSNKWYLALLLTFNLFQGGQSILSQYARGIGKSKIFAAGGVILTFLTGALNILFLVY FT LPLGITGYLMSLVLANVGTILFFAGTLSIWKEISFKIIDKKLIWQMLYYALPLIPSSIL FT WWLLNASSRYFVLFFLGAGANGLLAVATKIPSIISIFNTIFTQAWQISAIEEYDSHQKS FT KYYSDVFHYLATFLLLGTSAFMIVLKPIVEKVVSSDYASSWQYVPFFMLSMLFSSFSDF FT FGTNYIAAKQTKGVFMTSIYGTIVCVLLQVVLLPIIGLDGAGLSAMLGFLTTFLLRVKD FT TQKFVVIQIKWRIFISNLLIVLAQILCLFYLPSEFLYFGLALLFCGMLVVNQRTILYII FT MALKIKNKTFGMKSS" FT terminator 14335..14346 FT /gene="epsM" FT CDS complement(14378..14953) FT /codon_start=1 FT /transl_table=11 FT /gene="orf14.9" FT /product="Orf14.9 protein" FT /db_xref="InterPro:IPR006976" FT /db_xref="UniProtKB/TrEMBL:Q56051" FT /protein_id="AAC44021.1" FT /translation="MRKYMIYLSSLLITFILSYATITWLIMPVLTRYQSLAKLINHFDY FT TTLTLILLLTLIIWLFGIQYHLKYFSVIYLYLAFSVYLLLLFMVLFTKITDFQAMSLNP FT FDFIKADPRTIQEAVLNIIYFIPLGGLYCINTDFKQFVIVSLVTLLVIETIQFIFYLGT FT FAISDIILNFLGCLIGYYCCWEIKRRLS" FT -10_signal complement(14990..14995) FT /gene="orf14.9" FT -35_signal complement(15010..15015) FT /gene="orf14.9" XX SQ Sequence 15250 BP; 5154 A; 2176 C; 2912 G; 5008 T; 0 other; gatcctttac gtgcaaaatt tattgccgaa aatttccttg aagatgctgt gtgtttcaac 60 gaagtacgta acatgtttgg ttacacagga acatacaagg gtgaacgtat ctcagtaatg 120 gggactggga tggggatgcc atctatctct atctatgcac gtgagctcat tgttgactac 180 ggtgtcaaaa aattaattcg cgtaggaact gccggttctt tgaatgagaa tgttcacgtt 240 cgtgagttgg ttctagcaca agcagcagca actaactcta atattattcg taatgactgg 300 cctcaatacg actttcctca aattgcaagt ttcaatctct tggataaggc ttatcacatc 360 gccaaaaatt ttggtatgac aacacatgtt ggtaatgttc tatcttctga tgaaaagtac 420 tcaaattatt ttgaaaaaaa tattgaactt gggaaatggg gcgtgaaggc tgtcgaaatg 480 gaagcagcag cactttacta ccttgcagcc caacaccaag tagatgctct ggctattatg 540 actatttctg atagtttggt aaatccagat gaggacacaa cagctgagga acgtcaaaac 600 actttcactg atatgatgaa agttggtctt gaaacactaa ttgcagacta gtttgtaaaa 660 ggacgccatt tggtcgtcct tttgtgttgt agctaatatc tgttcgaagt gataataagt 720 taaaattttt caaactacta gaaaaaataa aaatatttgg aagaagaaga cttataataa 780 ataggtaaat atctgacaat ttaaagttta actactaaaa atgtaaaaga tagttcacaa 840 tataatggaa aatgatataa attaaatgat tgatatcata atgaaaaacg ttttcttatt 900 tttttgaaaa aagaatgaca attgaaatga ggttgtatta atgttataat aataataata 960 atggggaata cctaatttta atttttagga gcaatttata tgagttcgcg tacgaatcgt 1020 aagcaaaagc atacgagtaa tggatcgtgg gggatggtca acgttgggtt gaccatcctg 1080 tatgctattt tagcattggt cttattattc accatgttca attataattt cctatccttt 1140 aggtttttga acatcattat caccattggt ttgttggtag ttcttgctat tagcatcttc 1200 cttcagaaga ctaagaaatt accactagtg acaacggttg tactggttat cttctcgcta 1260 gtttctctgg ttggtatttt tggttttaaa caaatgattg acatcactaa ccgtatgaat 1320 cagacagcag cattttctga agtagaaatg agcatcgtgg ttcctaagga aagtgacatc 1380 aaagatgtga gccagcttac tagcgtacag gcacctacta aggttgataa gaacaatatc 1440 gagatcttga tgtcagctct caaaaaagat aaaaaagttg atgttaaagt tgatgatgtt 1500 gcctcatatc aagaagctta tgataatctc aagtctggca aatctaaagc tatggtcttg 1560 agtggctctt atgctagcct attagagtct gtcgatagta attatgcttc aaatctaaaa 1620 acaatttata cttataaaat taaaaagaag aatagcaact ctgcaaacca agtagattca 1680 agagtcttca atatttatat tagtggtatt gatacctacg gtccgatttc aacagtgtca 1740 cgttcagatg tcaatatcat tatgacagta aacatgaata cacataagat tctcttgacg 1800 actactccac gtgatgcata cgttaagatt cctggtggtg gggcagacca gtatgataaa 1860 ttaacccacg caggtattta tggcgttgaa acatctgaac aaactctaga agatctttat 1920 ggtattaagc ttgattacta tgcacgaatt aacttcacat ctttccttaa gttgattgac 1980 caacttggtg gtgtgacagt ccataatgat caagctttca cacaagagaa gtttgatttc 2040 ccggttggag atatccaaat gaattcagag caagcacttg gatttgttcg tgaacgctat 2100 aatttagatg gcggagataa tgaccgtggt aaaaaccagg agaaagttat ttctgcgatt 2160 ttaaacaagt tggcttctct aaaatctgta tcaaacttta cttcaatcgt taataatctc 2220 caagactctg tccaaacgaa tatgtctttg aataccatta acgctttggc taatacacaa 2280 cttgaatcag gttctaaatt tacggtgact tctcaagcag taacaggtac aggttcaacc 2340 ggacaattga tctcttatgc gatgccaaat tctagtcttt acatgatgaa actagataat 2400 tcgagtgtgg aaagtgcctc tcaagctatc aaaaaattga tggaggaaaa ataagtgatt 2460 gacgttcact cacatattgt ttttgatgtt gatgatggtc ctgaaacttt agaagaaagt 2520 ttagacctca ttggtgaaag ttacgcccag ggggtacgta agattgtttc aacatcccat 2580 cgtcgtaagg ggatgtttga gactccagag gataaaattt ttgccaactt taaaaaagta 2640 aaagcagaag cagaagcact ttatccagac ttaactattt attatggagg tgaactttat 2700 tacacctcag acattgtgga gaaacttgaa aagaatctca ttccgcgcat gcacaacact 2760 caatttgctt taattgagtt tagtgctcgc acatcttgga aagaaattca tagtgggctt 2820 agtaatgttt tgagagcggg ggtaacgcct attgttgctc atattgagcg ctatgatgcc 2880 ctcgaagaaa atgctgaccg tgttcgagaa atcatcaata tgggctgcta tactcaagtc 2940 aatagctcac atgtcctcaa accaaagctc tttggagata aagataaagt aagaaagaaa 3000 cgtgttcgct ttttcttgga gaaaaatttg gttcatatgg ttgctagcga catgcataat 3060 cttgggccga gaccaccatt tatgaaagat gcttatgaaa ttgttaaaaa gaactacggc 3120 tccaaacgtg ctaagaatct ttttattgaa aatcccaaaa cattactaga aaatcaatat 3180 ttataggaga tattatgaat caagataaca ctaaaagtga tgaaatcgac gtactagcat 3240 tgctacataa actttggacg aagaagcttt tgattctttt cacagctttt tatttcgctg 3300 ttttcagttt cttaggtact tatttcttta tccaaccaac atatacatca acaacgcgta 3360 tctatgttgt taatcaggca acagataata agaatctttc tgctcaagat ttgcaagctg 3420 gtacctattt ggcaaatgac tataaagaga ttattgcatc aaatgatgta ttatcagaag 3480 ttattaaaga tgaaaaattg aatttgagtg aggcagaact gtctaaaatg gtttcagtta 3540 atattcctac tgatactcgt cttatttcaa tttctgttaa tgctaaaact ggtcaagatg 3600 cgcaaacact tgccaataag gttcgtgaag ttgcttcaaa aaaaatcaag aaggtgacaa 3660 aagttgaaga tgtcacaacg ctcgaagaag ctaaattgcc agagtcacca tcttcaccaa 3720 atatcaaact taatgtgctt cttggggcag tgcttggagg attccttgca gtggttggtg 3780 tattggtacg tgaaatccta gatgatcgtg ttcgccgtcc agaagatgtg gaagatgccc 3840 ttggaatgac acttcttgga attgtccctg atacagataa aatttaagga gaagaaatgc 3900 ctttattaaa gttagttaaa tcaaaagtag actttgctaa aaagacggaa gagtattata 3960 acgctattcg cacaaatatt caattttctg gtgctcagat gaaagtgatt gcgattagct 4020 ctgttgaagc tggtgaagga aaatcaatga tatctgttaa cttggcgatt tcatttgcta 4080 gtgttgggct ccgaacactt ctgattgatg cggaaacgcg taattctgtt ttgtcaggta 4140 catttaaatc aaatgagcct tataaaggtc tttcaaattt cctttcagga aatgccgatc 4200 taaatgaaac gatttgccaa actgatattt ctggtttaga tgttattgca tctggtcctg 4260 ttccacctaa tccaacaagt cttttgcaaa atgataattt tagacatttg atggaagttg 4320 ctcgtagttg ttatgattat gtcatcatcg atacaccacc agttggtctg gttattgatg 4380 cagttattat tgcccatcag gctgatgcca gtcttttggt tacagaagct gggaaaatta 4440 aacgtcgttt cgtaactaag gccgttgaac aattggtaga aagtggttct cagttcttag 4500 gggtcgtcct taataaagtt gacatgacag ttgataaata tggattttat ggttcttacg 4560 gatcatatgg cgagtatgga aaaaaatctg accaaaaaga aggtcattca agagcacatc 4620 gtcgtagaaa agtcggttgg aattaacgcg ttagtgtgtt ttaagatgtc gttgggaacg 4680 acaagtggag ggaatgagat gtcacaagct aaagaggaaa tttcagatgt tatgacttat 4740 tcagagctaa caagtcataa gcccaaaatt atttatagct tgattaagcg gattggtgat 4800 attttggtta gttctattgg tttaattatt ttgataccgc tatttttgat agttgctttg 4860 atcatgaaat gctctgaacc aacagcacct atatttttct cacatattag aaatggtaaa 4920 aatggcaaaa agttcaaaat gtataaattt agaaccatgt gtcaggacgc agaatcgatt 4980 ttgatgaaag atacggaact ttttgcaaaa tttaaggcaa atggttataa acttgaaacg 5040 catgaagatc ctagaattac aaaaatcggt ggcatattaa ggaaaacaag tattgatgaa 5100 ttgccacaac tgattaatgt ttttttagga caaatgtcat tagtgggtcc acgtccacta 5160 ccagatagag aaatcattga atacggtgat aaccaagaaa aatttttaag cgttaaacca 5220 ggcatgacag gatggtggca agtttcaggg agaagtacta ttgggtatcc tgagcggtgt 5280 catcttgagc tttattatgt agaaaagtgt tgttttactt tcgatgttct tatattactt 5340 aagacaattg ggattgtttt gaagagagtt ggagcgcgtt agtactgatg aaacaaaaat 5400 tattattgat aatagaagcg atgagtggtg gagccggtcg tcatgtacaa gacttgatta 5460 gtcatctacc tcaagaaaaa tttgatattt atgtgattta ttcaaatcat agaacaaatc 5520 ctgttttttg gaaaaaatag taacgatgaa tgagcaagta acttttattt tatgtgattt 5580 tctcgtaaga gaaattaaac cgaaatatga tttgcttgct tatcaattta tttctaaaaa 5640 gattaaagaa atcaaaccag atattgtaca ttgtcacagt tcaaaagctg gtgttattgg 5700 tcgtttagct gccaaaagac gaggtgttaa aaaaatattt tatacgccac atgcttattc 5760 gtttttggca cctgaattta gtgggaagaa aaagtttcta tttgttcaaa ttgaaaagtt 5820 tttaagccga tttgcgacaa ctaagatatt ttgtgtgtca atagcggaaa tgcaagctgc 5880 tcttgaagta aatctagata aaaccgataa gtttcaggta atttataatg gtttgccaga 5940 aattgattta ccaagcaaag aaacgattcg ggcgcaatta ggactggaaa aggcagcagt 6000 tgttataggc aataatgcaa aaatgtcgga acagaaaaat cctatgtttt ttatggaaat 6060 tgcccgaaaa atgattagac aaaacgcaaa ttggcatttt gtgtgggtag gtgatggtca 6120 gctgatgcca ctttttcaat catttattaa gcaaaatgga ctagagggaa atatccattt 6180 gcttggcgag cgtcctgata gtgaaatagt tgtgacagcc tatgacatct tcttgacgac 6240 ttcccaatat gaaggtttac cttatgcacc aattgaagcg atgcgagctg gtgtcccgat 6300 tcttgcgaca aaagttgttg gcaatagtga gcttgtgata gagggcaaaa atggttattt 6360 gattgactta gagtggtcaa aatctgtcga agaaaaatta tataaggcag cgaaaataga 6420 tgcacaaatg attaaagcag attttaggca aaggtttgcg attgatcaga tattaaagca 6480 aattgaaaca atttatttag cttgaatgaa gaatgaggag gcataaatgc tgattttgaa 6540 attaaaattt catcttaatt ggtacacaaa cgaaaaccat tattacacgt gagtattcga 6600 agacctggaa acgaggcgat gagccgtatt atccagtgaa caatgatcgt aacaacaaac 6660 tctatactgc ctataagcgt cttgccgagc aacaagagaa tgtcattttc ggtggacgtc 6720 taggtcacta ccgttactac gatatgcacc aggtaattgg agctgccttg cagtgtgtca 6780 gaaatgaagt gaagtaaatc ttgatgaagt tgaataactt taagtaattt tatacttaat 6840 ccaattgatg aaaatatttt tgtatcgatt tatcttctgt aagaagagtc ctaatcgttt 6900 aaaaaatgta caattgagtt tttatatttt taaataaagt tacttttaag tcgtgttata 6960 gaatatacat gaataggtgt attagaaaat ttattaatct aatcctcgaa aataactgac 7020 tgtaaggaat caagttgtgg agtgtaagtt gtcaaatgga gaggaaaata atatgaaaaa 7080 aatttcaatt ttacactttt cccaagtatc aggcggggga gttgaaaagt acataaaatt 7140 atttttaaag tattctgatg tgacaaaatt taataattat ttagttgcac ctaatcttga 7200 aaattatgac gaatttaatg gatatttaaa gatgtctgtc aattttaata tggaacaaac 7260 tttttctccg ctaaaaatat tcaaaaatgt cttttttatt cgtagtgtac tcaaaaaaat 7320 aaacccagat atagtatacc tacatagtac atttgcaggt gtcgtaggtc gtattgcttc 7380 aataggtttg ccaacaaaag tagtatacaa tcctcacgga tggtccttca aaatggacaa 7440 cagctatttg aaaaagctta tttttaaatt aatcgaattt tctttatctt ttttaactga 7500 taagtttatt ttaatttcgg aatctgagta tattttggct aaccatattt catttaataa 7560 aagcaagttt tcactaatta ataatggtgt tgaagtgatt acaggggatt caagaaatga 7620 gatagaagag atatttccaa atgaggattt tataattggc atggttggca gactaagccc 7680 acccaaagag tttttctttt ttattgattt tgcaaaaaaa atattacaaa ttcgaaacga 7740 taccaatttt attatcgtgg gtgatggaga gttacgaagt gaaatagaaa gaatgatact 7800 agataatggg ttaggagata aaatctatat tactgggtgg gttgataatc cgagaaacta 7860 tatagagaag tttgatcaag ctattctgtt ttctagatgg gagggtctta gcctaacgat 7920 tgcggaatat atgtctcaga agaaaacaat tttagcaaca aatattggtg gcattaatga 7980 tttaatcact gatggtgaaa caggaatgct gattgaagtt ggagacttga attcagcagt 8040 atctaaatct ttcgagctaa gaaataataa agaggtttcg aatcaattag cgaataacgc 8100 ttataataaa gttgttgaac agttttcgat tgaaaaacag atggctgaga tagaaagttt 8160 atttatagag atgtgtaaca atgagaaata gagacttaaa gaaaatacag gttatttgat 8220 tgacttagag tggtcaaaat ctgtcgaaga aaaattatat aaggcagcga aaatggatgc 8280 acaaatgatt aaagcagatt ttaggcaaag gtttgcgatt gatcagatgt taaagcaaat 8340 taaaacaatt tatttagctt gaatgaagaa agaggaggca taaatgctga ttttgaaatt 8400 aaaatttcat cttaaatcgt tattccttaa atggatttat cgattacttt atctaaaaaa 8460 gtttcagttt ggtgcacgct tgacgtttcg agatgggttt catttgttaa ttgaaaaatc 8520 tgggaaagtt atcatcggga atcatgtttt ttttaataac ttttgttcaa ttaatgccat 8580 gttatcagta acgattggtg atgactgtat ttttggtgaa aacgttaaaa tttatgatca 8640 caatcattgt tatcaaaata aaagtcaacc tatttcaaaa caaggttttt caactgctgc 8700 tatccagatt ggtcgtaact gttggatagg tagtcaagtg acgattttaa aaggtgtaac 8760 cataggtgat aatagtatca ttggtgctgg tgtggtagtt tatcaagatg tgccagaaaa 8820 ttcgattgtt ttatctaatg gagaaattag aaagcgtggc taattaaaat gtatcttaaa 8880 agtctaatct ctattgttat tccagtatat aatgtagaga aatatttaga aaaatgtttg 8940 caatctgttc aaaatcagac ttacaataat tttgaagtga ttttagtgaa tgatggctca 9000 accgattcat cactttcaat atgcgaaaaa tttgttaatc aggataaaag attttctgtt 9060 ttttctaaag aaaatggtgg tatgtcatct gcacgaaatt ttggaattaa aaaggctaaa 9120 ggatcgttta tcacatttgt agatagtgat gactacatag taaaagatta tctttctcat 9180 ttggtagctg ggataaaaag tgagacctct atagtttgtt caaagttttt tcttgtagat 9240 gaaaaaggaa gtttattgac taaaaaagag gcacctaaaa agaaatcaga agtcgtttca 9300 attgaggaaa gtattaaaat tcttctgttg caacaaaatg gctatgatct cgctgtctgg 9360 ggaaaattat accccgtttc tttctttgaa acaatttctt tcccagaagg aaaactttac 9420 gaagatatgg gaacaactta caaattacta aaattggcaa gtgaagtggt cttcttggat 9480 gcgtatgatt atgcctacgt acagcgacct aatagtatca tgaatagttc ttttaatttg 9540 aaaaagttgg atataataga aatggttcat gaaatggaaa acgatatatt agcacagttt 9600 ccaaatttag cattatatgt taagaatcga gcatttgccg cggaagtgaa aatcttttta 9660 gagattccaa aagaaaaaga atttgagcaa gcgcaaaagc aactttggca tgatatcaaa 9720 aagaatagaa aagcaccatt tatgacaaaa ggtgctagat tgaagaatag gctcggagct 9780 agtctgtcgt ttttaggtaa atctttattt ttgactattg ggaagcagtt agtagataga 9840 taatgatatt gaaagcgata cgatacaatc gtaaacttct tttggtgttg actaggagtt 9900 agcttgaaat ttgaatataa aggaagcaac acatggtaat ttatttttta cttttcccga 9960 tgatcgcaat gatttattta atgacattgc tcttacggca aaaagcacaa atccaaaaaa 10020 cgattttttg tgttcttacg tttggtacac taggctttat ttcagcaagt cgtgcatcaa 10080 gtgttgggac ggacgttact ttatacgaaa atatttttaa atctataaat tacgggataa 10140 gtgctgagaa taattgggga tacgtcatct ataacaagct gattggtagt gtatttggct 10200 atacaggaca tgaaatcacg gccgctaatt cagttttgat tacaatactt attggtattt 10260 ttatttggaa agtagcggaa cattattttg ttgcgacgtt tttatacatt agcttgtttt 10320 attatgctac aagttttaat atttcaagac aatttattgc catggggctt gtattggtag 10380 caatttcttt tgctttagat aaaaaggtta tgccttggtt tatcttgaca gttttggcta 10440 ccttatttca tgcgacagca atcgttgctt ttcctgtcta ttggcttaca aaagtacatt 10500 gggatgtgaa aaagacatta agtatttttc caatcacgat ttttgcaagt tttatttttg 10560 atgctatttt aaacattttt gtacgttttt tcccacatta tgagatgtat atcactggaa 10620 cacaatttaa tatttcagat caggggcagg gacgtgtggt tttggtcaaa atatttatct 10680 tgctcatttt gtttacttta ttcttgtttt ataaaaaaag ctatgctttg atttctgaat 10740 gtcatcaaag tttgatagct ttgacaaccg ttggattaag tatcggtatt gtattttata 10800 ataatatttt actcaataga atagaaatgt tttattcaat tttaagcatc gtatttattc 10860 caattgctat agattacatt agtttgaaat ttaaacaaaa agatgctgtg cgactaatgc 10920 tgacgatagg tattttgtta attacacttg tgccttacta tatacaggtt agcggtaatt 10980 attcaggaat attgccttat gttattcaac aataaaaaat aaagtttaga gaggaaataa 11040 tggaggatag aaagaaacaa gtaattttga tactatccca cagaaatact ctcgctctaa 11100 aatcaacaat agagcttttg gattctcaat actttgattt ctttcttcat atagataaaa 11160 aaagtagaat tcaagatttt ttttatttaa aaaaaattac aaaattctcc actattcatt 11220 tttcagaaag aaaaaatgta cattggggag gtttttctat ggtagaagca atgtttgcgc 11280 tattagaatg tgcacgtgat acaggagaat attcttattt tcatttttta tctggagatg 11340 atatgccaat caaagataat gaaatagtat ttaatttttt tgaaaatagt tatcctaaaa 11400 attttattga tattctagat tttgaaaatg tcaataaaaa ttcatatttc tacgaacccc 11460 ctgagatgat agaggagaga gtgaagtact actatcctca tatggatatt ctaaacagaa 11520 aaggaacaaa tttcataggg aaaaaactaa tttatctaca aaaattgttg aaagttaatc 11580 gcttgaaaaa tagagagata gaaattttca agggtcatca atggtgtagt ttgacaaatc 11640 aatttgtaga tattttattg gataaagagg aaagaagagt aggtaagtct tatttttcat 11700 ctagtttaat accagatgaa tgttattttc aaacgtttgc tatgataaaa aaagttgaaa 11760 tttatcaaca gaaaaatatg tcagcacgct taattgattg gacaagaggg aaaccatata 11820 tttggcgaca ggatgatttt tttgaaatta tgaatgataa agattcaatg ttttctagga 11880 agtttgatga aaatgtagat cgtaaaataa ttgaagaaat ttatataaaa ataagaggaa 11940 gaagtactga tgaagcaaat aaaatcaaag ataagagatt tacaaaataa ttttacctat 12000 gtttttggaa agaaaacttt tcttggaagg ggagaagcga ttatcataga tgaacctgag 12060 catggaaatt tgggagatca agcaattgct tttgcagaaa atcaattttt agtaaatcat 12120 gtatcagtac gagatgtaga acatcttata gaaagcaaaa ctatttcaga aataaaatct 12180 ataaaaaaaa atattggaaa aaaagaatta gttttttttc atgggggagg aaatttcggg 12240 acactttatc taaagtatga gcgcattaga agattggcag tatcaaagct tccctttaat 12300 aaaatgattc tatttcctca gtcaatttca tttgaagata gtaggtttgg tcagaagcag 12360 ctgaataaaa gtaaaaaaat atacagtcaa aatacaaatt ttattttgac tgcaagagaa 12420 ccaaaatctt atggtttaat gaagaaatgt tttccatata acaaagtaat cttgacaccg 12480 gatatcgtgc tctcatttaa atttgaagtc accatttctg atacgcatat tgggaaagaa 12540 aaggatagtg ttataactta tgaaaatcgt caacactatc ttgagataaa gtgggatgaa 12600 attgcgcagc atgaggtcgc cttaactgat agattacatg gtatgatttt ttcatatatc 12660 acaggcacac catgtgttgt tttggctaat aataatcata aaattgaagg aacatacaaa 12720 cattggttga atgaagtcaa ctatattcgt tttattgaaa atccgactgt tgaaaatatt 12780 ttagatgcaa tcaatgactt aaagcaaatc gaacctcact atattgattt atctgataaa 12840 tttcaaccac taattgatgc gataaaaggg taaaggttta atgaataaat ataaaaaact 12900 actatccaac tctcttgttt tcacgatagg aaacttaggc agcaaactgt tagtcttttt 12960 actcgtaccg ctctacacct atgcgatgac accgcaagag tatggtatgg cagacttata 13020 tcaaacaaca gcaaatctac ttttgccatt aattacaatg aatgtatttg atgcaacttt 13080 acgttttgct atggaaaagt caatgacaaa agagagtgtg ttaacaaatt ctcttgtggt 13140 ttggtgtttt agcgcggtgt tcacttgttt gggcgcttgt attatctatg cgttgaactt 13200 gagtaataaa tggtatttag ctttactttt aaccttcaac ttatttcaag gtggacaaag 13260 tatattaagc cagtatgcta gaggtatagg aaagtcgaaa atatttgcag ctggcggagt 13320 tattttaacc tttttgacag gcgctttaaa tattcttttt ttggtatatt taccgcttgg 13380 gattacgggc tatttaatgt ccctggtttt agcgaatgta ggtacgattc tattttttgc 13440 tggcacactt tccatttgga aggaaattag ttttaaaata attgataaaa aactgatttg 13500 gcaaatgctc tattatgcct tacctttgat tcctagttcc atcctgtggt ggttactgaa 13560 tgcttctagt cgctatttcg ttttattctt tttaggagca ggtgctaatg gtcttttggc 13620 ggtcgctacc aaaattccaa gtattatttc catttttaat acgattttta cacaggcgtg 13680 gcaaatttca gccatagaag aatatgattc tcatcaaaaa tcaaaatatt attcggatgt 13740 ttttcactac ttagcaactt ttctattgtt agggacatca gcttttatga ttgtgcttaa 13800 accaattgtc gaaaaagtcg tttcaagtga ctatgcaagt tcatggcaat atgttccttt 13860 ctttatgttg tcgatgctat tttcctcgtt ttctgatttt tttgggacta attatattgc 13920 ggctaaacaa acaaaaggcg tatttatgac atctatctat ggtaccattg tttgtgtctt 13980 actccaagtg gtgctgctac ccatcatcgg cttggatggc gcaggtttat cagccatgct 14040 tggattttta acaacgtttt tattgcgtgt caaagatacg caaaaatttg tggtgattca 14100 gattaagtgg cggattttta tcagtaattt attgatcgtt ttggcacaaa ttttatgttt 14160 gttttatcta ccgagtgaat ttttgtattt tggtcttgcc ctattatttt gtggcatgtt 14220 agtggttaat cagcgtacaa ttttatacat tatcatggcg ctaaaaataa aaaataagac 14280 atttggaatg aaatcctcat aaaaatagac aggaggtgta tctcgaatgg tatcgagata 14340 tatctcctgt ctatttttat gatacttttg tgttagctca actcaaccgc cttttaatct 14400 cccaacaaca ataataccca atcaaacaac ccaaaaaatt caagataata tcactaatgg 14460 caaatgtgcc caaataaaag ataaattgaa tggtttcaat tactaaaaga gtgaccaaac 14520 tgacaatgac aaactgtttg aaatcagtat tgatacagta aaggccacct aaaggaatga 14580 agtagataat atttagcaca gcctcttgaa tcgttctggg atccgctttt ataaagtcaa 14640 aaggattcag tgacatcgcc tgaaaatccg ttattttagt aaaaagtacc atgaataaca 14700 gtaataaata cacactgaaa gcaagataga gataaataac tgaaaaatat ttgaggtgat 14760 actggatacc aaacaaccag ataatcagcg ttaataagag tattaaagtc aatgtggtat 14820 agtcaaagtg gttaatcaac ttagccaggc tttgatagcg agtgagaacg ggcataatca 14880 gccaagtaat cgtcgcataa ctcaggataa atgtgatcaa taaactgctg aggtagatca 14940 tatattttcg caactgtttc taactccttt tcttgatgag attaacccta ttttaacata 15000 ttttaaaact gtcatgtttt tatgaattta aaataaatgt taaagaaaat aaaaattcac 15060 cagttggttc tgttgcaaag ttttccaaaa aatctatttt agtgtaaaat tgagaaaaaa 15120 gacagagagg acagagtaat gaattatttt aaaggcaaac aattcaaaaa agacgtcatt 15180 attgtctctg ttggttacta cctgcgttac aatctaagct atcgttaagt tcaggaattg 15240 ttatatgatc 15250 // |
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