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EBI DbfetchID U34346; SV 1; linear; genomic DNA; STD; PRO; 9470 BP. XX AC U34346; XX DT 27-OCT-1995 (Rel. 45, Created) DT 31-AUG-2006 (Rel. 89, Last updated, Version 6) XX DE Paracoccus denitrificans NAD-GSH-dependent formaldehyde dehydrogenase DE (flhA), ClpP (clpP), S-formylglutathione hydrolase (fghA), PQQ-dependent DE dehydrogenase large subunit (xoxF), cytochrome c553i (cycB), XoxJ (xoxJ), DE and XoxI (xoxI) genes, complete cds. XX KW . XX OS Paracoccus denitrificans OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales; OC Rhodobacteraceae; Paracoccus. XX RN [1] RP 5659-7354 RX PUBMED; 1657873. RA Ras J., Reijnders W.N.M., Van Spanning R.J.M., Harms N., Oltmann L.F., RA Stouthamer A.H.; RT "Isolation, sequencing, and mutagenesis of the gene encoding cytochrome RT c553i of Paracoccus denitrificans and characterization of the mutant RT strain"; RL J. Bacteriol. 173(21):6971-6979(1991). XX RN [2] RP 980-2317 RX PUBMED; 7798140. RA Ras J., Van Ophem P.W., Reijnders W.N., Van Spanning R.J., Duine J.A., RA Stouthamer A.H., Harms N.; RT "Isolation, sequencing, and mutagenesis of the gene encoding NAD- and RT glutathione-dependent formaldehyde dehydrogenase (GD-FALDH) from Paracoccus RT denitrificans, in which GD-FALDH is essential for methylotrophic growth"; RL J. Bacteriol. 177(1):247-251(1995). XX RN [3] RP 1-9470 RX PUBMED; 8892832. RA Harms N., Ras J., Reijnders W.N.M., van Spanning R.J.M., Stouthamer A.H.; RT "S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to RT human esterase D: a universal pathway for formaldehyde detoxification?"; RL J. Bacteriol. 178(21):6296-6299(1996). XX RN [4] RP 1-9470 RA Ras J.; RT ; RL Thesis (1995), Unknown Institution XX RN [5] RP 1-9470 RA Harms N., Ras J., Koning S., Reijnders W.N., Stouthamer A.H., RA van Spanning R.J.; RT "Genetics of C1 metabolism regulation of Paracoccus denitrificans"; RL Unpublished. XX RN [6] RP 1-9470 RA Harms N.; RT ; RL Submitted (21-AUG-1995) to the EMBL/GenBank/DDBJ databases. RL Nellie Harms, Microbial Physiology, Vrije Universiteit, de Boelelaan 1087, RL 1087 HV Amsterdam, The Netherlands XX FH Key Location/Qualifiers FH FT source 1..9470 FT /organism="Paracoccus denitrificans" FT /mol_type="genomic DNA" FT /db_xref="taxon:266" FT CDS <1..350 FT /codon_start=3 FT /transl_table=11 FT /product="unknown" FT /note="orf1" FT /db_xref="InterPro:IPR007401" FT /db_xref="UniProtKB/TrEMBL:Q51668" FT /protein_id="AAC44549.1" FT /translation="YLWFSMGWLTLTLGVIGVFVPVLPTVPFLLLAVWAFMRSSPRLGA FT RIMRHPQFGPPIRAWRKRGVIGRGAKIWAVAGMSAGVAWAVWLGLDPRFIAAQALACTA FT IAAWLVTRPEI" FT CDS 441..1025 FT /codon_start=1 FT /transl_table=11 FT /product="unknown" FT /note="orf 2" FT /db_xref="GOA:Q51669" FT /db_xref="InterPro:IPR006913" FT /db_xref="InterPro:IPR014185" FT /db_xref="PDB:1X6M" FT /db_xref="PDB:1XA8" FT /db_xref="UniProtKB/Swiss-Prot:Q51669" FT /protein_id="AAC44550.1" FT /translation="MVDTSGVKIHPAVDNGIKPAQPGFAGGTLHCKCSTNPVRVAVRAQ FT TAHNHVCGCTKCWKPEGAIFSQVAVVGRDALEVLEGAEKLEIVNAEAPIQRHRCRDCGV FT HMYGRIENRDHPFYGLDFVHTELSDEDGWSAPEFAAFVSSIIESGVDPSRMEAIRARLR FT ELGLEPYDALSPPLMDAIATHIAKRSGALAA" FT CDS 1129..2256 FT /codon_start=1 FT /transl_table=11 FT /gene="flhA" FT /product="NAD-GSH-dependent formaldehyde dehydrogenase" FT /function="oxidation of S-hydroxy methyl glutathione to FT S-formylglutathione" FT /note="GD-FALDH" FT /db_xref="GOA:P45382" FT /db_xref="InterPro:IPR002085" FT /db_xref="InterPro:IPR002328" FT /db_xref="InterPro:IPR011032" FT /db_xref="InterPro:IPR013149" FT /db_xref="InterPro:IPR013154" FT /db_xref="InterPro:IPR014183" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:P45382" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC44551.1" FT /translation="MRTRAAVALEAGKPLEVMEVNLEGPKAGEVMVEIKATGICHTDEF FT TLSGADPEGLFPSILGHEGAGVVVEVGPGVTSVKPGNHVIPLYTPECRQCASCLSGKTN FT LCTAIRATQGQGLMPDGTSRFSMLDGTPIFHYMGCSTFSNYTVLPEIAVAKVREDAPFD FT KICYIGCGVTTGIGAVINTAKVEIGAKAVVFGLGGIGLNVLQGLRLAGADMIIGVDLND FT DKKPMAEHFGMTHFINPKNCENVVQEIVNLTKTPFDQIGGADYSFDCTGNVKVMRDALE FT CTHRGWGQSIIIGVAPAGAEISTRPFQLVTGRVWKGTAFGGARGRTDVPQIVDWYMDGK FT IEIDPMITHTLSLDDINKGFDLMHAGESIRSVVLY" FT CDS 2332..2967 FT /codon_start=1 FT /transl_table=11 FT /gene="clpP" FT /product="ClpP" FT /db_xref="GOA:P54414" FT /db_xref="InterPro:IPR001907" FT /db_xref="InterPro:IPR018215" FT /db_xref="UniProtKB/Swiss-Prot:P54414" FT /protein_id="AAC44552.1" FT /translation="MAKISTWTTMTTMTTSAARKGLRTRGSACPRATRSASSISSRAQV FT IVAGPITDKLAQRTVAHLLALAEDSDEPINMLISSPGGHVESGDMIHDVIKFIRPTVRT FT IGLAWVASAGALIFVGADKENRYCLPNTRFLIHQPSVGIGGTSTDMMIQAEQVRLMRDR FT LNQIFAEATGQPVERIEKDTQRDFWLNTQEALDYGLLGKVIRSVDELK" FT CDS 2964..3485 FT /codon_start=1 FT /transl_table=11 FT /product="unknown" FT /note="orf 3" FT /db_xref="GOA:Q51670" FT /db_xref="InterPro:IPR000182" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q51670" FT /protein_id="AAC44553.1" FT /translation="MSAGGTGILIRPATPDDHQAIWAILEPVYRAGETYCIPPDISRDE FT ALADWFAAPFTVFVAELDGRVLGTSHVGRNRPGPASHVANASFATHPDARGHGIARELV FT GHAKDWARAQGFRAMQFNFVVSTNADAVHSWQKAGFDIVGRLPAAFLHPRHGYVDALVM FT FHDLTEGKNP" FT CDS 3482..4321 FT /codon_start=1 FT /transl_table=11 FT /gene="fghA" FT /product="S-formylglutathione hydrolase" FT /function="hydrolyzation of S-formylglutathione to formate FT and reduced glutathione" FT /note="similar to human esterase D; FGH" FT /db_xref="GOA:A1AXZ2" FT /db_xref="InterPro:IPR000801" FT /db_xref="InterPro:IPR014186" FT /db_xref="UniProtKB/Swiss-Prot:A1AXZ2" FT /protein_id="AAC44554.1" FT /translation="MTLAYETVSENRSFGGIQGVYRHQSQATGTPMTFAIYLPPDARHG FT KVPVLWYLSGLTCTHENAMTKAGAQEWAAEYGIAVIFPDTSPRGEGVANDETYDLGQGA FT GFYVDATEAPWAPHFRMWHYVTHELPELVFNNFPLDREAQGITGHSMGGHGALTIAMTF FT PERYRSVSAFAPIAHPSESDWGRKQFAAYLGDDKAAWKRHDSTILMREKGYPGEVLIDQ FT GASDQFLDLLKPEALAHAMAERRQPGTFRMQQGYDHSYFFVQSFMADHIPLARGALG" FT CDS 4523..6325 FT /codon_start=1 FT /transl_table=11 FT /gene="xoxF" FT /product="PQQ-dependent dehydrogenase large subunit" FT /function="unknown" FT /db_xref="GOA:P29968" FT /db_xref="InterPro:IPR001479" FT /db_xref="InterPro:IPR002372" FT /db_xref="InterPro:IPR011047" FT /db_xref="InterPro:IPR017512" FT /db_xref="InterPro:IPR018391" FT /db_xref="InterPro:IPR019551" FT /db_xref="InterPro:IPR019556" FT /db_xref="UniProtKB/Swiss-Prot:P29968" FT /protein_id="AAC44555.1" FT /translation="MKNLMNGACLALLMSGTAALANEQRAGRDRQAPQWAIQMGDYANT FT RYSTLDQINKDNVKDLRVAWTFSTGVLRGHEGSPLVIGDVMYVHTPFPNRVFALDLNDN FT GKILWRYEPQQDPNVIAVMSCDTVYRGLSYADGMILLGQADTTVVALDATSGEVKWSTK FT IGDPGIGETLTATVVPVKDKVLVGISGGEYGVRGRMTALNLTDGSEAWKAWSTGPDEEL FT LVDPETTTHLGKPIGADSSLNSWEGDQWQIGGGTIWGWFSYDPDLNLVYYGTGNPSTWN FT PSQRPGDNKWSMTIMARDADTGMAKWFYQMTPHDEWDYDGVNEMILTNQTVDGQERKLL FT THFDRNGLAYTMDRETGELLVAEKYDPVVNWTTGVDMDPNSETYGRPAVVAEYSTAQNG FT EDENTTGVCPAALGTKDQQPAAFSPKTNLFYVPTNHVCMDYEPFRVAYTAGQPYVGATL FT SMYPAPNSHGGMGNFIAWHNTTGEIKWSVPEQFSVWSGALATAGDVVFYGTLEGYLKPV FT DAQTGEELYKFKTPSGIIGNVMTYEHGGKQYVGILSGVGGWAGIGLAAGLTNPNDGLGA FT VGGYASLSQYTELGGQLTVFELPG" FT CDS 6427..7107 FT /codon_start=1 FT /transl_table=11 FT /gene="cycB" FT /product="cytochrome c553i" FT /db_xref="GOA:Q51672" FT /db_xref="InterPro:IPR009056" FT /db_xref="UniProtKB/TrEMBL:Q51672" FT /protein_id="AAC44556.1" FT /translation="MTSKTTASLLAICVACAASAIAGTALCADRRNAPAQAGAGAAAAV FT SGDAHEQPAAEAPAEEEEETPAVAATDGKLVLPNGQDITPDHMENGRWYTAEDIPTYKI FT AEDGAVDWATFSGYRRYSAECHVCHGPDGEGSTYAPALRKSVLTMGYYDFLEIAASGKQ FT EVNTAANLVMPAFGTNKNVWCYIDDIYAYLLARGTGDLPRGRPAKREDKSDEFVAQEDS FT CMSG" FT CDS 7104..7907 FT /codon_start=1 FT /transl_table=11 FT /gene="xoxJ" FT /product="XoxJ" FT /db_xref="GOA:Q51673" FT /db_xref="InterPro:IPR001638" FT /db_xref="UniProtKB/TrEMBL:Q51673" FT /protein_id="AAC44557.1" FT /translation="MRRALTLAVLATCAVLPALAQVADLRSKTEFRVCADPAAVPMSSQ FT DGKGFENRIAQLFAEKLGVPVAYTWFPQGPGFIRKTLRAGLCDVVIGYAQGDEMVQNTN FT HYYTSAYGIVTRNDSPLASVEALDDPALGGHPIGVVAGTPPASNLARAGLAKNMRGWDL FT FVDRRVEDPVGDMLAQVKSGELAAAVIWGPLAGPLVKQDPELQFTPLLKESGGPRMFYR FT ITMGVRLGEQEWKRELNSLIRRHQDEIDAILRDAGVPLLDDYGRL" FT CDS 8035..8586 FT /codon_start=1 FT /transl_table=11 FT /gene="xoxI" FT /product="XoxI" FT /db_xref="InterPro:IPR019587" FT /db_xref="UniProtKB/TrEMBL:Q51674" FT /protein_id="AAC44558.1" FT /translation="MIRLLALTMGAALALAPAAEAHGPPRLKLEMQQKLDATPDEVWTA FT IGRFDDMSWHPAIASLELTGDGSADQPETSTRVLHLKSDAGDPTITEVLSKWQPEKHCY FT AYRIEAVEVTVLPVTNYAATLCVKDEGGKAVVNWKGGFYRGYPNNEPPPELSDEAAIKA FT VTGVYQAGLDALAERFGKAE" FT CDS complement(8770..9348) FT /codon_start=1 FT /transl_table=11 FT /product="unknown" FT /note="orf4" FT /db_xref="UniProtKB/TrEMBL:Q51675" FT /protein_id="AAC44559.1" FT /translation="MAETVIAEDLRSRGFTLLDPPADQVARIKNPTQSNGSDSRIARDM FT GAHYAISGEVQKVSNLILSLNLYIRDAESGDTVRAGVVDIRGNTDESFHGEPYRSETPA FT TLAGAQVIDAAEAMRLHAQGVPFIDVLPRTARPEGLPEARFGTNRRIFPFPARPGFTIP FT DMTGWPRRNRRGWPRGWHGCRGATGLRPW" XX SQ Sequence 9470 BP; 1740 A; 3046 C; 3113 G; 1571 T; 0 other; gatatctctg gttctccatg ggctggctga ccttgacgct gggcgtgatc ggggtcttcg 60 tgccggtcct gccgaccgtg ccgttcctgc tgcttgcggt ctgggccttc atgcgctcgt 120 ctccccggct gggcgcacgc atcatgcgcc acccgcaatt cggcccgccg atccgcgcct 180 ggcgcaagcg cggcgtcatc ggccgcgggg ccaagatctg ggccgtcgcc ggcatgtcgg 240 ccggcgtcgc atgggcggtc tggctgggcc ttgatccgcg cttcatcgct gcgcaggcat 300 tggcctgcac cgccatcgcc gcctggctgg tgacccgccc cgagatctga gccggcaggg 360 attacaacct tttgcccact tgttccggcc ctgccatggc gcgaacctcg gcgcataggt 420 ctgaggggag gaacgggacc atggtggata catcgggggt gaagatccac cccgcagtcg 480 acaacggcat caagccggcc cagcccgggt tcgcgggcgg cacgctgcat tgcaagtgca 540 gcaccaaccc ggtccgggtc gcggtccggg cgcagaccgc ccacaaccat gtctgcggct 600 gcacgaaatg ctggaagccc gagggcgcga tcttttcgca ggtggcggtg gtgggccgcg 660 atgcgctcga agtgctggaa ggcgccgaaa agctcgaaat cgtcaatgcc gaggccccga 720 tccagcgcca tcgctgccgg gattgcggcg tgcacatgta tggccggatc gagaacaggg 780 accatccctt ctacgggctg gatttcgtcc ataccgagct ttccgacgag gacggctggt 840 cggcgccgga atttgcggcc ttcgtcagct cgatcatcga atcgggggtc gatcccagcc 900 gcatggaggc gatccgcgcc agattgcgcg aactggggct ggagccctat gatgcgcttt 960 cgccgccgct gatggatgcg atcgccaccc atatcgcgaa acggtccggc gctcttgcgg 1020 cctgagcgcc tgacaggtca cgacgataaa cggcgggggt cggtttaccg gcccccgagg 1080 ccatgagaag cacaacaggc ccagggccga catgaaggag aagacaagat gagaacccgt 1140 gccgccgtgg cccttgaggc tggcaaaccg ctggaagtga tggaggtcaa cctggaaggc 1200 ccgaaggccg gcgaggtgat ggtcgagatc aaggccaccg gcatctgcca caccgacgaa 1260 ttcaccctgt cgggcgccga tcccgagggg ctcttcccct cgatcctggg ccatgagggc 1320 gcgggcgtcg tggtcgaggt cggcccgggc gttacctcgg tcaagccggg caatcatgtc 1380 atcccgctct acacgcccga gtgccggcaa tgcgcgtcct gcctgtcggg caagaccaac 1440 ctttgcaccg ccattcgcgc cacccagggt cagggcctga tgccggacgg aaccagccgg 1500 ttcagcatgc tcgacggcac gccgatcttt cattacatgg gctgctcgac cttctcgaac 1560 tacaccgtgc tgccggaaat cgcggtggcc aaggtgcgcg aggacgcgcc cttcgacaag 1620 atctgctata tcggctgcgg cgtcactacc ggcatcggcg cggtgatcaa caccgccaag 1680 gtggaaatcg gcgccaaggc ggtggtcttc ggcctgggcg gcattgggct gaacgtgctg 1740 caggggctgc gcctggccgg cgcggacatg atcatcggcg tcgatctgaa cgacgacaag 1800 aagccgatgg ccgagcattt cggcatgacg catttcatca acccgaagaa ttgcgagaac 1860 gtggtgcagg agatcgtgaa cctgaccaag acgcccttcg accagatcgg cggcgcggat 1920 tacagcttcg actgcaccgg caacgtcaag gtgatgcgcg acgcgctgga atgcacccat 1980 cgcggctggg gccagtcgat catcatcggc gtggcgccgg cgggggccga gatcagcacc 2040 cgcccgttcc agctggtcac cggccgggtc tggaagggca cggccttcgg cggtgcccgc 2100 ggccgcaccg acgtgccgca gatcgtcgac tggtatatgg acggcaagat cgagatcgac 2160 ccgatgatca cccacaccct gtcgctggac gacatcaaca agggcttcga cctgatgcat 2220 gcgggcgaat ccatccgctc ggtcgtcctt tactgatcgt caagggctgc ttagttaaaa 2280 ggccggcggg ggcgggcgac cggccccgcc gtcaacatga aaggaccgat catggcaaag 2340 atttccacct ggacgacgat gacgacgatg acgacgagcg ccgccaggaa gggtctaagg 2400 acgaggggct cggcctgccc gagggcgaca agatcggcaa gctctatttc aagtcgcgca 2460 caggtgatcg ttgccgggcc gatcaccgac aagctggcgc agcgcaccgt ggcgcatctg 2520 ctggccctgg ccgaggacag cgacgagccg atcaacatgc tgatctcgtc gcccggcggc 2580 catgtcgaat ccggcgacat gatccatgac gtgataaagt tcatccgccc gaccgtgcgc 2640 accatcggct tggcctgggt cgcctcggcc ggcgcgctga tctttgtcgg cgcggacaag 2700 gaaaaccgct attgcctgcc caacacccgc ttcctgatcc accagccctc ggtcgggatc 2760 ggcggcacgt ccacggacat gatgatccag gccgagcagg tgcggctgat gcgcgaccgg 2820 ctgaaccaga tctttgccga ggccaccggc cagccggtcg agcggatcga aaaggacacc 2880 cagcgcgact tctggctgaa cacgcaagag gcgctggact acggcctcct gggcaaggtc 2940 atccgctcgg tggacgagct gaaatgagcg cgggcgggac aggcatcctg atccgtcccg 3000 ccacgcccga cgaccatcag gcgatctggg cgatcctgga gcccgtctat cgggcgggcg 3060 agacctattg catcccgccc gacatctcgc gggacgaggc gctggccgac tggttcgccg 3120 cgcctttcac ggttttcgtg gccgagctgg acgggcgagt gctgggcacc agccatgtcg 3180 gccgcaaccg gcccggcccc gcaagccatg tcgccaatgc cagctttgcc acccacccgg 3240 atgcgcgtgg ccatggtatc gcccgcgaac tggtcggcca tgccaaggat tgggcgcggg 3300 cgcagggttt ccgggcgatg cagttcaact tcgtcgtctc gaccaatgcc gatgccgttc 3360 attcgtggca gaaagccggt ttcgatattg tcgggcgcct gccggctgca tttcttcatc 3420 cccggcatgg ctatgtggat gcgctggtca tgttccacga cttgacagaa gggaagaacc 3480 catgacgctg gcctatgaaa ccgtatcgga aaaccgcagc ttcggcggta tccagggcgt 3540 ctatcgccac cagtcccagg cgaccggcac gccgatgacc tttgccatct acctgccgcc 3600 cgatgcccgg cacggcaagg tgccggtgct gtggtatctt tcgggcctga cctgcacgca 3660 tgaaaatgcc atgaccaagg ccggcgcaca ggaatgggcg gcggaatacg gcatcgcggt 3720 gatctttccc gacacctcgc cgcgcggcga aggcgtggcc aacgacgaga cctacgacct 3780 gggccagggc gccggcttct atgtcgatgc gaccgaggcg ccctgggcgc cgcatttcag 3840 gatgtggcac tatgtcaccc atgaactgcc cgagctggtc ttcaacaact tcccgctgga 3900 ccgcgaggcg cagggcatca ccggccattc catgggcggg cacggtgcgc tgaccatcgc 3960 catgaccttc ccggagcgct atcgctcggt ctcggccttt gcgccgatcg cgcatcccag 4020 cgaatccgac tgggggcgca aacagttcgc cgcctatctg ggcgacgaca aggcggcatg 4080 gaaaaggcat gattcgacca tcctgatgcg cgaaaagggc tatcccggcg aggtgctgat 4140 cgaccagggc gcgagcgacc agttcctcga tcttctgaag cccgaggcgc tggcccatgc 4200 catggccgaa cgccgccagc ccggcacctt ccgcatgcag cagggctacg atcacagcta 4260 tttcttcgtg caaagcttca tggccgacca tatcccgctg gcacgcggag ccttgggcta 4320 ggcgggccgg gcccggccaa agggcaacgg ggcagggtgg gggcagggcg attgccccat 4380 acctattgcc gaatttccct aatactttgg tccaaggagc ctgccggccg cgttgacgca 4440 aatgcggccg gacccgaacc ttccagcagt aggtgcttgc gcatgaggag aggcgcgacc 4500 accggcatgc ggaggaaaat tcatgaaaaa cctaatgaat ggcgcctgcc ttgcgctgct 4560 catgtccggc actgcggcgc tggccaatga acagcgtgct ggccgagatc gccaagcccc 4620 gcaatgggcg atccagatgg gcgattacgc gaacacgcga tattcgaccc tggaccagat 4680 caacaaggac aacgtcaagg atctgcgcgt cgcctggacc ttctcgaccg gggtgctgcg 4740 cggacacgaa ggctcgccgc tggtgatcgg cgatgtcatg tatgtccaca ccccctttcc 4800 gaaccgggtg tttgcgctgg acctgaacga caacggcaag atcctgtggc gctatgaacc 4860 gcagcaggat ccgaacgtaa ttgcggtgat gtcctgcgac acggtctatc gcggcctttc 4920 ctatgcggac ggcatgatcc tgctgggcca ggccgacacc acggtcgtgg ccctggacgc 4980 cacgagcggc gaggtgaaat ggtcgaccaa gatcggcgac ccgggcatcg gcgagacgct 5040 gaccgccacc gtcgttccgg tcaaggacaa ggtcctggtc ggcatctcgg gcggcgaata 5100 cggcgtgcgc ggccggatga ccgcgctgaa cctcaccgat ggcagcgagg cctggaaagc 5160 ctggtccacc ggcccggacg aggagttgct ggtcgatccc gaaacgacca cgcatctggg 5220 caagcccatc ggcgccgaca gctcgctcaa cagctgggaa ggcgatcagt ggcagatcgg 5280 cggcggcacg atctggggct ggttctcgta tgacccggac ctgaacctgg tctattacgg 5340 caccggcaac ccctcgacct ggaacccctc gcagcggccg ggcgacaaca agtggtcgat 5400 gacgatcatg gcgcgggatg ccgataccgg catggccaag tggttctatc agatgacgcc 5460 ccatgacgaa tgggactatg acggcgtcaa cgagatgatc ctgaccaacc agaccgtcga 5520 cgggcaagag cgcaagctgc tgacccattt cgaccgcaac ggcctggcct atacgatgga 5580 tcgcgagacc ggcgagttgc tggtggccga gaaatacgat ccggtggtga actggaccac 5640 cggcgtcgac atggacccga attcggaaac ctatggccgt ccggccgtgg tggccgaata 5700 ctcgaccgcc cagaacggcg aggacgagaa caccaccggc gtctgccctg cggcactggg 5760 caccaaggac cagcagccgg cggccttctc gcccaagacc aacctgttct atgtgccgac 5820 gaaccacgtc tgcatggatt acgagccgtt ccgggtggcc tataccgccg gccagcccta 5880 tgtcggcgcc acgctgtcca tgtatcccgc gccgaacagc catggcggca tgggcaactt 5940 catcgcctgg cacaacacca cgggcgagat caagtggtcc gttcccgagc agttctcggt 6000 ctggtcgggc gctttggcta cggcgggcga cgtggtcttc tacggcacgt tggagggcta 6060 tctgaagccc gtcgatgccc agacgggcga ggagctttac aagttcaaga ccccctcggg 6120 catcatcggc aacgtgatga cctacgaaca tggcggcaag cagtatgtcg gcatcctgtc 6180 gggtgtcggc ggctgggccg ggatcggcct tgccgcgggc ctgaccaatc ccaacgatgg 6240 gcttggcgcg gtgggcggct atgcctcgct gtcgcaatat accgagctgg gcggccagct 6300 gaccgtgttc gaactgccgg gctaatactt tggtgccgga aagcaaactg tgactcgaaa 6360 ctgggcgccc caggggtaac cttggggcgc gccatcatct tcgggtgaca gccagggagg 6420 aaattcatga ccagcaagac gaccgccagt cttttggcga tctgtgtcgc atgcgcggcc 6480 tctgccatcg ccggaacggc cctttgcgca gaccgccgaa acgccccggc ccaggccggg 6540 gcaggcgctg ccgccgccgt ctcgggcgat gcgcacgagc aaccggccgc ggaagcgccc 6600 gccgaagagg aggaggagac gccagcggtc gccgcaacgg acggcaagct tgtgctgccg 6660 aacggccagg acatcacccc ggaccatatg gagaacggcc ggtggtatac ggccgaggat 6720 atcccgacct acaagatcgc cgaggacggc gcggtggatt gggcgacctt ctcgggctat 6780 cgccgctatt ccgccgaatg ccatgtctgc cacggcccgg atggcgaggg ttcgacctat 6840 gccccggccc tgcggaaatc ggtgctgacc atgggctatt acgatttcct ggagatcgcc 6900 gcctcgggca agcaagaggt caacaccgcc gccaatctgg tcatgccggc ctttggcacc 6960 aacaagaacg tctggtgcta tatcgacgac atctatgcct atctgctggc gcggggcacg 7020 ggagacttgc cgcgcggccg cccggcgaag agagaggaca agtccgatga attcgttgcg 7080 caggaagatt cctgcatgag cggatgagac gcgcccttac ccttgccgtc ctggcgacct 7140 gcgccgtgct gcccgccttg gcgcaggttg ccgacctgcg ctccaagacc gagttccggg 7200 tctgtgccga tcccgccgcg gtgccgatgt cgtcccagga cggcaagggc ttcgagaacc 7260 gcatcgccca gcttttcgcc gaaaagctgg gcgtgccggt cgcctatacc tggttcccgc 7320 agggtcccgg cttcatccgc aagaccctgc gcgccgggct gtgcgatgtc gtcatcggct 7380 atgcccaggg cgacgagatg gtgcagaata ccaatcatta ctacacctcg gcctatggca 7440 tcgtgacgcg caatgacagc ccgctggcct cggtcgaggc gctggatgat ccggcgctcg 7500 gtggccatcc tatcggcgtg gtggcgggca cgccgcctgc aagcaacctg gcgcgggcgg 7560 ggctggccaa gaacatgcgc ggctgggacc tgttcgtgga tcgccgggtc gaggacccgg 7620 tgggcgacat gcttgcgcag gtgaagtcgg gcgaactggc tgccgcggtg atctggggtc 7680 cgctggccgg accgctggtc aagcaggatc ctgaactgca attcaccccg cttctcaagg 7740 aaagcggcgg gccgcgcatg ttctatcgca tcaccatggg cgtgcgcttg ggcgagcagg 7800 aatggaagcg cgagctgaac agcctgatcc gccgccacca ggacgagatc gacgccatcc 7860 tgcgcgatgc cggggtgccg ctgctggacg attacggaag gctttgaaac aatgagatgg 7920 gcttgggcgg cgatggctgt ggttgttgcc ggcgcggcca ggcccgagcc gccaagcttt 7980 cgccgcggct atctctacct attgaaaaac atcatctttc tggaggagtg acggatgatc 8040 cgactgttgg ccctgacgat gggagcagcc ctggcgctgg caccggccgc cgaggcgcac 8100 ggcccgccgc ggctgaagct ggagatgcag caaaagctgg atgccacccc ggacgaggtc 8160 tggaccgcaa tcggcagatt cgacgacatg agctggcatc cggcgatcgc cagcctggaa 8220 ctgaccggcg acggctcggc cgaccagccc gagacatcca cccgcgtgtt gcatctgaaa 8280 tccgacgcag gcgacccgac catcaccgag gtcctgtcga aatggcagcc cgaaaaacac 8340 tgctatgcct atcggatcga ggcggtcgag gtgacggtcc tgccggtgac gaattatgcc 8400 gcgacgcttt gcgtcaagga tgagggcggc aaggccgtgg tcaactggaa gggcggcttc 8460 tatcgcggct atccgaacaa cgagcctccg cccgaactga gcgacgaggc ggcgatcaag 8520 gcggtaaccg gagtctatca ggccggtctc gacgcgctgg ccgaaaggtt cggcaaggcg 8580 gaatgaccaa tccgccgcct gccggcctct tgacgagtca tgggccggca gggctggcag 8640 gttccaggga accgccctgc tcttgccagc cctcgacccc gtcgggaaac cagatcacgc 8700 cgcgatagcc cagcgccacg gcgcgcttgg cggcattcca gctcatccag cagtcgcgct 8760 tgcaaaagat caccatgggc gcagccctgt cgccccccga cagccgtgcc agcccctcgg 8820 ccagccgcgc ctgttccgcc ggggccagcc ggtcatatcc ggtatcgtaa agccaggccg 8880 cgccgggaat ggaaagatgc ggcggttcgt tccaaaacgt gcttcgggca agccctcggg 8940 ccgggcggtg cggggcagaa cgtcgataaa gggcacgcct tgcgcatgca gccgcatcgc 9000 ctcggccgca tcgatcacct gcgcgccggc cagggtggcc ggggtctcgg accgataggg 9060 ctcgccatga aagctttcgt cggtattgcc gcggatatcg accacgccgg cgcggaccgt 9120 gtcgccgctt tcggcatcgc ggatataaag gttcagggac aggatcaggt tcgagacctt 9180 ctgcacctcg cccgagatcg cgtaatgcgc gcccatatcg cgcgcaatgc ggctgtcgct 9240 gccgttggac tgggtcgggt tcttgatccg cgccacctgg tcggcgggcg gatcgagcag 9300 ggtaaaaccg cggctgcgca ggtcctcggc gatgaccgtc tcggccatct cgatgcggcg 9360 ggtctcgtcc tcgcgcacgc cgttgatcgc gccctcggtc gaggtgtcga tgaaatgcag 9420 gccggaacca gacggcgctg tcgggcgatg gtgcggaacc gtgagccggc 9470 // |
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