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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   U28976; SV 1; linear; mRNA; STD; HUM; 1278 BP.
XX
AC   U28976;
XX
DT   06-JAN-1999 (Rel. 58, Created)
DT   04-MAR-2000 (Rel. 63, Last updated, Version 4)
XX
DE   Human apoptotic cysteine protease Mih1/TX isoform alpha (mih1/Tx) mRNA,
DE   complete cds.
XX
KW   interleukin-1 beta converting enzyme.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1278
RA   Fernandes-Alnemri T., Litwack G., Alnemri E.S.;
RT   "Cloning of human ICE homolog Mih1";
RL   Unpublished.
XX
RN   [2]
RP   1-1278
RA   Alnemri E.S.;
RT   ;
RL   Submitted (12-JUN-1995) to the EMBL/GenBank/DDBJ databases.
RL   Emad S. Alnemri, Pharmacology, Thomas Jefferson University, Jefferson
RL   Cancer Institute, 233, S. Tenth Street, Philadelphia, PA 19107, USA
XX
DR   ASTD; TRAN00000052557.
DR   H-InvDB; HIT000218944.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1278
FT                   /organism="Homo sapiens"
FT                   /mol_type="mRNA"
FT                   /clone="mih1-alpha clones 5, 14 and 15"
FT                   /cell_line="Jurkat"
FT                   /cell_type="T-lymphocyte"
FT                   /db_xref="taxon:9606"
FT   CDS             34..1167
FT                   /codon_start=1
FT                   /gene="mih1/Tx"
FT                   /product="Mih1/TX isoform alpha"
FT                   /note="This product, designated mih1-alpha, is an active
FT                   protein as determined by its ability to cleave synthetic
FT                   peptide substrates; This cDNA is similar to the TX cDNA
FT                   described recently by Faucheu et al., EMBO J. 4:1914-1922
FT                   (1995)"
FT                   /db_xref="GOA:A2NHL8"
FT                   /db_xref="HGNC:1505"
FT                   /db_xref="InterPro:IPR001309"
FT                   /db_xref="InterPro:IPR001315"
FT                   /db_xref="InterPro:IPR002138"
FT                   /db_xref="InterPro:IPR002398"
FT                   /db_xref="InterPro:IPR011029"
FT                   /db_xref="InterPro:IPR011600"
FT                   /db_xref="InterPro:IPR015917"
FT                   /db_xref="InterPro:IPR016129"
FT                   /db_xref="InterPro:IPR017350"
FT                   /db_xref="UniProtKB/TrEMBL:A2NHL8"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="AAC99850.1"
FT                   /translation="MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKY
FT                   YDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTD
FT                   ALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDITGMK
FT                   ELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHD
FT                   EKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ
FT                   SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLE
FT                   EVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN"
FT   polyA_site      1278
FT                   /gene="mih1/Tx"
FT                   /note="23 A nucleotides"
XX
SQ   Sequence 1278 BP; 406 A; 295 C; 288 G; 289 T; 0 other;
     caacgctgta aaaaaggaca gaggctgttc cctatggcag aaggcaacca cagaaaaaag        60
     ccacttaagg tgttggaatc cctgggcaaa gatttcctca ctggtgtttt ggataacttg       120
     gtggaacaaa atgtactgaa ctggaaggaa gaggaaaaaa agaaatatta cgatgctaaa       180
     actgaagaca aagttcgggt catggcagac tctatgcaag agaagcaacg tatggcagga       240
     caaatgcttc ttcaaacctt ttttaacata gaccaaatat cccccaataa aaaagctcat       300
     ccgaatatgg aggctggacc acctgagtca ggagaatcta cagatgccct caagctttgt       360
     cctcatgaag aattcctgag actatgtaaa gaaagagctg aagagatcta tccaataaag       420
     gagagaaaca accgcacacg cctggctctc atcatatgca atacagagtt tgaccatctg       480
     cctccgagga atggagctga ctttgacatc acagggatga aggagctact tgagggtctg       540
     gactatagtg tagatgtaga agagaatctg acagccaggg atatggagtc agcgctgagg       600
     gcatttgcta ccagaccaga gcacaagtcc tctgacagca cattcttggt actcatgtct       660
     catggcatcc tggagggaat ctgcggaact gtgcatgatg agaaaaaacc agatgtgctg       720
     ctttatgaca ccatcttcca gatattcaac aaccgcaact gcctcagtct gaaggacaaa       780
     cccaaggtca tcattgtcca ggcctgcaga ggtgcaaacc gtggggaact gtgggtcaga       840
     gactctccag catccttgga agtggcctct tcacagtcat ctgagaacct ggaggaagat       900
     gctgtttaca agacccacgt ggagaaggac ttcattgctt tctgctcttc aacgccacac       960
     aacgtgtcct ggagagacag cacaatgggc tctatcttca tcacacaact catcacatgc      1020
     ttccagaaat attcttggtg ctgccaccta gaggaagtat ttcggaaggt acagcaatca      1080
     tttgaaactc caagggccaa agctcaaatg cccaccatag aacgactgtc catgacaaga      1140
     tatttctacc tctttcctgg caattgaaaa tggaagccac aagcagccca gccctcctta      1200
     atcaacttca aggagcacct tcattagtac agcttgcata tttaacattt tgtatttcaa      1260
     taaaagtgaa gacaaacg                                                    1278
//
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