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EBI DbfetchID U23458; SV 1; linear; genomic RNA; STD; VRL; 7038 BP. XX AC U23458; XX DT 02-NOV-1995 (Rel. 45, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 4) XX DE Sudan Ebola virus Maleo strain RNA-dependent RNA polymerase (L) gene, DE complete cds. XX KW . XX OS Sudan ebolavirus OC Viruses; ssRNA negative-strand viruses; Mononegavirales; Filoviridae; OC Ebola-like viruses. XX RN [1] RP 1-7038 RA Sanchez A., Trappier S., Nichol S.T.; RT ; RL Submitted (25-MAR-1995) to the EMBL/GenBank/DDBJ databases. RL Anthony Sanchez, Special Pathogens Branch, Division of Viral and RL Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 RL Clifton Road, Bldg. 15, Room SB611, Mail Stop G14, Atlanta, GA 30333, USA XX FH Key Location/Qualifiers FH FT source 1..7038 FT /organism="Sudan ebolavirus" FT /strain="Maleo 1979" FT /mol_type="genomic RNA" FT /note="subtype: Sudan" FT /db_xref="taxon:186540" FT 5'UTR 1..78 FT misc_signal 1..12 FT /note="transcription start site" FT CDS 79..6711 FT /codon_start=1 FT /gene="L" FT /product="RNA-dependent RNA polymerase" FT /function="polymerase activity in transcription and FT replication" FT /note="L protein" FT /db_xref="GOA:Q66802" FT /db_xref="InterPro:IPR001016" FT /db_xref="UniProtKB/Swiss-Prot:Q66802" FT /protein_id="AAA79970.1" FT /translation="MMATQHTQYPDARLSSPIVLDQCDLVTRACGLYSEYSLNPKLRTC FT RLPKHIYRLKYDAIVLRFISDVPVATIPIDYIAPMLINVLADSKNAPLEPPCLSFLDEI FT VNYTVQDAAFLNYYMNQIKTQEGVITDQLKQNIRRVIHKNRYLSALFFWHDLSILTRRG FT RMNRGNVRSTWFVTNEVVDILGYGDYIFWKIPIALLPMNSANVPHASTDWYQPNIFKEA FT IQGHTHIISVSTAEVLIMCKDLVTSRFNTLLIAELARLEDPVSADYPLVDDIQSLYNAG FT DYLLSILGSEGYQIIKYLEPLCLAKIQLCSQYTERKGRFLTQMHLAVIQTLRELLLNRG FT LKKSQLSKIREFHQLLLRLRSTPQQLCELFSIQKHWGHPVLHSEKAIQKVKNHATVLKA FT LRPIIIFETYCVFKYSVAKHFFDSQGTWYSVISDRCLTPGLNSYIRRNQFPPLPMIKDL FT LWEFYHLDHPPLFSTKIISDLSIFIKDRATAVEQTCWDAVFEPNVLGYSPPYRFNTKRV FT PEQFLEQEDFSIESVLQYAQELRYLLPQNRNFSFSLKEKELNVGRTFGKLPYLTRNVQT FT LCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGEHATVRGSSFVTDLE FT KYNLAFRYEFTAPFIKYCNQCYGVRNVFDWMHFLIPQCYMHVSDYYNPPHNVTLENREY FT PPEGPSAYRGHLGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVMGDNQCITVLSVF FT PLESSPNEQERCAEDNAARVAASLAKVTSACGIFLKPDETFVHSGFIYFGPKQYLNGIQ FT LPQSLKTAARMAPLSDAIFDDLQGTLASIGTAFERSISETRHILPSRVAAAFHTYFSVR FT ILQHHHLGFHKGSDLGQLAINKPLDFGTIALSLAVPQVLGGLSFLNPEKCLYRNLGDPV FT TSGLFQLKHYLSMVGMSDIFHALVAKSPGNCSAIDFVLNPGGLNVPGSQDLTSFLRQIV FT RRSITLSARNKLINTLFHASADLEDELVCKWLLSSTPVMSRFAADIFSRTPSGKRLQIL FT GYLEGTRTLLASKMISNNAETPILERLRKITLQRWNLWFSYLDHCDSALMEAIQPIRCT FT VDIAQILREYSWAHILGGRQLIGATLPCIPEQFQTTWLKPYEQCVECSSTNNSSPYVSV FT ALKRNVVSAWPDASRLGWTIGDGIPYIGSRTEDKIGQPAIKPRCPSAALREAIELTSRL FT TWVTQGSANSDQLIRPFLEARVNLSVQEILQMTPSHYSGNIVHRYNDQYSPHSFMANRM FT SNTATRLMVSTNTLGEFSGGGQAARDSNIIFQNVINFAVALYDIRFRNTCTSSIQYHRA FT HIHLTDCCTREVPAQYLTYTTTLNLDLSKYRNNELIYDSEPLRGGLNCNLSIDSPLMKG FT PRLNIIEDDLIRLPHLSGWELAKTVLQSIISDSSNSSTDPISSGETRSFTTHFLTYPKI FT GLLYSFGALISFYLGNTILCTKKIGLTEFLYYLQNQIHNLSHRSLRIFKPTFRHSSVMS FT RLMDIDPNFSIYIGGTAGDRGLSDAARLFLRIAISTFLSFVEEWVIFRKANIPLWVVYP FT LEGQRPDPPGEFLNRVKSLIVGIEDDKNKGSILSRSEEKCSSNLVYNCKSTASNFFHAS FT LAYWRGRHRPKKTIGATKATTAPHIILPLGNSDRPPGLDLNQSNDTFIPTRIKQIVQGD FT SRNDRTTTTRLPPQSRSTPTSATEPPTKIYEGSTTYRGKSTDTHLDEGHNAKEFPFNPH FT RLVVPFFKLTKDGEYSIEPSPEESRSNIKGLLQHLRTMVDTTIYCRFTGIVSSMHYKLD FT EVLWEYNKFESAVTLAEGEGSGALLLIQKYGVKKLFLNTLATEHSIESEVISGYTTPRM FT LLSVMPRTHRGELEVILNNSASQITDITHRDWFSNQKNRIPNDVDIITMDAETTENLDR FT SRLYEAVYTIICNHINPKTLKVVILKVFLSDLDGMCWINNYLAPMFGSGYLIKPITSSA FT RSSEWYLCLSNLLSTLRTTQHQTQANCLHVVQCALQQQVQRGSYWLSHLTKYTTSRLHN FT SYIAFGFPSLEKVLYHRYNLVDSRNGPLVSITRHLALLQTEIRELVTDYNQLRQSRTQT FT YHFIKTSKGRITKLVNDYLRFELVIRALKNNSTWHHELYLLPELIGVCHRFNHTRNCTC FT SERFLVQTLYLHRMSDAEIKLMDRLTSLVNMFPEGFRSSSV" FT 3'UTR 6712..7038 FT polyA_signal 7027..7038 FT /note="transcription stop/polyadenylation signal" XX SQ Sequence 7038 BP; 2186 A; 1449 C; 1361 G; 2042 T; 0 other; gaggaagatt aagaaaaagt ccataatgct gggtggacaa tccttgccac cataggactt 60 tttcaattcc tctactttat gatggctacc caacatacac aatatcctga tgcaagattg 120 tcttccccaa tcgttttaga ccaatgtgac ctagtgacaa gagcatgcgg actgtactct 180 gagtattcgc tgaaccctaa actaagaaca tgccgcttgc cgaaacatat ctatagatta 240 aaatatgacg ccattgtttt acgatttatc agtgatgtcc ctgtagctac aatcccaata 300 gattacattg ctccaatgtt aataaatgtt ctggcagata gtaaaaatgc accattagaa 360 cctccctgtt tgagcttcct agatgagata gtcaattata ctgtgcagga tgcggcattc 420 cttaattatt acatgaatca gattaaaaca caggaaggag taattacaga tcaattaaaa 480 cagaacattc gtagggtcat tcacaaaaac agatatttat ctgctctatt tttctggcat 540 gatctctcca tcctcacccg tcgagggaga atgaaccgag gaaatgtgcg ctccacttgg 600 tttgtaacga atgaggttgt tgatatccta ggatatggtg attatatttt ctggaagatc 660 cctattgctc tattaccaat gaactcagct aatgttcctc atgcatcgac tgactggtac 720 caacctaata tcttcaagga ggctattcaa ggacacacac acattatttc agtctctaca 780 gccgaggttc ttattatgtg taaggatctt gtcacaagtc gttttaacac ccttctgatt 840 gctgagttag ccaggttgga agatccagtg tccgctgatt atccactggt agatgatatt 900 caatctctgt ataatgcagg agactacttg ttgtccatat tgggatcgga ggggtaccaa 960 ataatcaagt atctcgagcc tctgtgtttg gctaagattc aactatgttc ccaatataca 1020 gaacgaaaag ggcggttttt aacccagatg catcttgcag ttattcaaac attgcgtgaa 1080 cttctcctta atagagggtt gaaaaaatca cagctttcta aaatccgtga gttccaccaa 1140 ctgttgctca gacttcgatc tacaccacaa caattatgtg aattattttc aatccaaaag 1200 cactggggcc atccagttct gcatagtgaa aaggccatac aaaaggttaa aaatcatgca 1260 acagttctaa aggcattgcg tccgattatc atctttgaaa cgtactgtgt attcaagtac 1320 agtgttgcaa aacatttctt tgatagccaa ggcacttggt acagtgtgat atcagaccga 1380 tgtttaacgc cgggattgaa ttcctacatt aggcgaaatc aattcccacc acttccaatg 1440 atcaaagatc ttctatggga attttaccat ttggatcatc ctccattatt ctccacgaag 1500 atcattagtg atctcagcat tttcattaaa gaccgtgcaa cagcagttga acaaacctgt 1560 tgggatgcag ttttcgagcc taacgttttg ggctacagtc caccttatcg attcaacacc 1620 aagcgtgtac ccgaacaatt cctggagcaa gaggattttt ctattgagag tgtcttacaa 1680 tacgcccaag aacttaggta cctattgccc cagaatcgaa atttttcttt ttcattgaaa 1740 gaaaaagaat taaatgttgg taggacattt ggaaaattgc cttatttaac taggaatgtc 1800 caaaccctct gcgaagcatt acttgcagat ggtttggcta aagcctttcc aagcaacatg 1860 atggttgtca cagagaggga acaaaaggag agcctccttc accaagcatc ttggcatcat 1920 acgagtgatg atttcggaga gcatgccaca gttcgcggga gtagttttgt cacagaccta 1980 gagaaatata atctggcttt caggtatgaa ttcacagctc ccttcatcaa atattgcaac 2040 caatgctatg gggttcgcaa tgtctttgat tggatgcact tcctaattcc gcaatgttac 2100 atgcatgtta gtgattatta taacccacca cataatgtaa ctttagagaa tagggaatat 2160 cctcccgaag gaccaagtgc ttatcgaggc caccttggtg gtattgaggg gcttcaacaa 2220 aagttatgga ctagcatctc atgtgctcaa atttcattgg tagagatcaa gaccggattc 2280 aaattgcgat cagcagtcat gggggataat caatgtatca cagtattatc agtctttcca 2340 ctagaatcca gtccgaatga gcaagagaga tgtgcagaag acaatgcagc cagagtagct 2400 gctagcttgg ccaaagtcac aagtgcctgt gggatattcc tcaagcctga tgagactttc 2460 gtacactcag gctttatcta ttttggccca aagcaatact taaacggaat tcaattgcct 2520 caatcactca agacagcagc taggatggcc cctctctcag atgcaatttt tgatgacttg 2580 cagggtacac ttgccagtat aggaactgcc tttgagcgat caatctccga aactagacat 2640 attttaccat ctcgtgttgc agctgccttt catacatatt tctctgttcg gatcttacaa 2700 catcatcacc ttggcttcca taaaggttca gaccttggac aattggcaat caataaacct 2760 cttgattttg ggaccattgc actatcctta gcagttcccc aggtactggg tggattatcc 2820 ttcctaaatc cagaaaaatg tctttatcgc aacctgggtg accctgtgac ttcaggccta 2880 ttccagttga agcattatct atcaatggta ggtatgagtg atatctttca cgcacttgtt 2940 gcaaaaagtc cagggaattg tagcgcaatt gactttgttc taaacccagg agggttaaat 3000 gtccctggat cacaggatct aacatctttc cttcgtcaga ttgtcagaag gagtatcaca 3060 ctttcggcaa ggaataagtt aatcaacacg ctgtttcatg cctctgcaga tcttgaagat 3120 gaattagttt gtaaatggtt actttcttca acgcccgtca tgagccgttt cgcagccgat 3180 attttctcac gaacaccaag cgggaaaaga ttacaaatct tgggatatct cgagggaacc 3240 agaactttat tagcatctaa aatgataagc aataatgcag agacaccaat cttagagaga 3300 ctcagaaaga taacacttca aagatggaat ttatggttta gttacctaga tcattgtgac 3360 tcagccttaa tggaagcaat tcaaccaatt aggtgtactg ttgatattgc tcaaattctt 3420 agagaatact cctgggctca tattcttgga ggtagacagt taataggggc aacattgcca 3480 tgtatacctg agcagttcca aaccacatgg ttaaaacctt acgagcaatg tgtggaatgt 3540 tcatccacaa acaattctag tccatatgta tcagttgcat taaaaaggaa cgtggtcagc 3600 gcttggcctg acgcatctag attggggtgg acgattggtg atgggattcc ctatataggc 3660 tcaagaactg aggacaagat aggtcagccc gctattaagc cgaggtgccc atcagctgca 3720 ttgagggaag ctattgaatt gacctctagg ttaacctggg tcactcaagg tagtgcaaat 3780 agcgatcagt taattcgtcc ttttcttgag gcaagagtga acttgagtgt acaagaaatt 3840 cttcaaatga caccctcaca ttattccggt aatattgtgc atcggtataa tgatcagtat 3900 agccctcact cctttatggc caaccgcatg agtaacacag caacgcgctt gatggtatct 3960 acaaacacac taggagagtt ctccggaggg ggccaagctg cacgtgatag caacattata 4020 ttccaaaatg tgattaattt tgcagtagcc ttgtatgaca ttaggtttcg gaacacctgt 4080 acatcctcta ttcaatatca cagggctcat attcacctga cagattgttg tacgagggaa 4140 gtaccagccc aatacttaac atacacaacc acgctaaatc tagatttgag taagtatcgt 4200 aataatgaac tgatttatga ttcagagcca ctaagaggag gtctaaactg caacttatcg 4260 attgacagtc ctttgatgaa gggcccacgt ttaaatatta ttgaggatga cttaatacgg 4320 ttgccacatt tatccggttg ggaattagca aaaacagttt tgcaatccat aatttctgat 4380 agtagcaatt catcaacaga tcccattagc agcggtgaaa caagatcctt tacaacccac 4440 ttcttaacgt atcctaaaat agggctctta tacagttttg gagccctcat aagtttttat 4500 ttgggtaata ctatcttgtg cacgaaaaag atcggactta cagaatttct atactatctc 4560 cagaaccaga tccacaactt atcacataga tcccttcgaa tcttcaaacc gacattcaga 4620 cactcaagtg tcatgtctag gttgatggat atagacccca acttctcaat atatattggt 4680 gggactgcag gtgatcgtgg attatcggat gctgcaagat tatttctccg aatcgcaatt 4740 tcaactttct tgagctttgt tgaggagtgg gttatcttta ggaaggcaaa cattccacta 4800 tgggttgtct atcctctcga aggccaacgc cctgatcctc ctggtgaatt tttaaaccga 4860 gtaaaatctt taattgttgg gattgaggat gataaaaata aaggctctat actttcaaga 4920 tctgaagaga agtgctcttc aaatctagtt tataattgca aaagtacagc aagcaatttt 4980 ttccacgcat cattggctta ttggagaggt cgacatagac ctaagaagac tataggtgca 5040 actaaagcga caacagctcc acacatcatt ttgccgctag gaaattctga tcgaccgcct 5100 ggtctagatc ttaatcagag caatgatact tttattccta ccagaattaa acagatagtc 5160 caaggagact ctagaaatga cagaacaacc accacgagac ttccacccca aagtaggtcc 5220 accccaacat cagcaaccga gcctcctaca aaaatatatg agggttcgac aacctatcga 5280 ggaaaatcaa cagatacaca tttggatgag ggtcataatg ccaaagagtt cccattcaat 5340 ccgcatcgtt tagtagtacc attttttaaa ttaacaaaag atggggaata cagtatcgaa 5400 ccttcccctg aagaaagccg cagtaatata aaagggttac ttcaacattt aagaaccatg 5460 gttgatacta ccatatattg tcgcttcact gggattgttt catcaatgca ttataaatta 5520 gatgaagtac tatgggaata taataaattt gaatcagctg taaccctagc agagggggag 5580 ggttcaggtg ctttactact gatccaaaaa tacggcgtta agaagttatt tttgaataca 5640 cttgctactg aacatagtat tgagagtgaa gtgatatcag gttacaccac cccaagaatg 5700 ctactctcag ttatgcctag aacacatcgt ggtgagctag aggtcatatt aaataactca 5760 gctagtcaaa taactgatat tacacaccga gattggtttt caaatcaaaa aaataggatt 5820 ccaaatgatg ttgatattat taccatggat gctgaaacta cagaaaattt agatcgttca 5880 agattatatg aagcagtata tacgattatt tgtaatcata tcaatcctaa aactttaaaa 5940 gtggtcatct taaaagtctt cctcagcgat ttggatggga tgtgctggat taacaattat 6000 cttgctccta tgtttggatc aggatactta atcaaaccta taacatcaag tgcaaggtca 6060 agtgagtggt atttatgctt atctaatcta ctttcaactt tgagaactac tcagcatcaa 6120 acccaagcaa actgtcttca tgtcgtacaa tgtgctcttc aacagcaagt tcaaagaggg 6180 tcatattggc taagtcatct caccaaatac accacaagta gattgcacaa tagttatatt 6240 gcatttggtt ttccttcgtt agagaaggtc ctatatcata gatataatct tgttgattcg 6300 agaaatggac cattggtttc tatcacaaga caccttgccc tcctccaaac tgagatccgg 6360 gagttggtaa ctgattataa tcagctgcga caaagtcgaa cccagactta tcatttcata 6420 aaaacatcca agggacggat aactaaacta gtgaatgatt atctaagatt tgagttggtt 6480 atacgggctc ttaaaaataa ttccacatgg caccatgagt tgtacttact accagaactt 6540 ataggtgttt gccatcgatt taatcataca cgcaactgta catgcagtga aaggttcctg 6600 gttcaaacct tatatctaca ccggatgagt gatgctgaga taaaacttat ggaccggctc 6660 accagcctag tcaatatgtt tcccgaaggt ttcaggtcta gttcagtcta attctaactg 6720 catctcaggt tctagaagta ttttaaataa ccaggtatat atcaaagtca atacaagtgt 6780 aagaacaata tgcaagggac cacatttggc attagtttat tgactcttcc aatatacagc 6840 gttggaagca tcgattcaag gtttcgaaga cactctattg attatgttga taatgtaaat 6900 aataattttt cctagctatt atgactaaaa taaacaaatc tataacgaac atcacaacca 6960 aattgttgcc ctagttcata tattaaattc aaatttagaa gctaggttga ctccagttac 7020 ataagtatta agaaaaaa 7038 // |
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