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EBI DbfetchID U16782; SV 1; linear; genomic DNA; STD; PRO; 8684 BP. XX AC U16782; XX DT 15-NOV-1994 (Rel. 41, Created) DT 11-SEP-2007 (Rel. 93, Last updated, Version 9) XX DE Ralstonia eutropha LysR-type transcriptional regulator (tfdT), chlorophenol DE monooxygenase (tfdBII), maleylacetate reductase (tfdFII), dienelactone DE hydrolase (tfdEII), chlorocatechol 1,2-dioxygenase (tfdCII) and DE chloromconate cycloisomerase (tfdDII) genes, complete cds, insertion DE sequence ISJP4, and putative transport protein ORF tfdK gene, complete cds. XX KW . XX OS Ralstonia eutropha JMP134 OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Cupriavidus. OG Plasmid pJP4 XX RN [1] RP 1476-1547 RX PUBMED; 3036764. RA Streber W.R., Timmis K.N., Zenk M.H.; RT "Analysis, cloning, and high-level expression of 2,4-dichlorophenoxyacetate RT monooxygenase gene tfdA of Alcaligenes eutrophus JMP134"; RL J. Bacteriol. 169(7):2950-2955(1987). XX RN [2] RP 1-141 RX PUBMED; 2185214. RA Perkins E.J., Gordon M.P., Caceres O., Lurquin P.F.; RT "Organization and sequence analysis of the 2,4-dichlorophenol hydroxylase RT and dichlorocatechol oxidative operons of plasmid pJP4"; RL J. Bacteriol. 172(5):2351-2359(1990). XX RN [3] RP 631-1547 RX DOI; 10.1016/0378-1119(91)90555-P RX PUBMED; 1650732. RA Ferrante A.A., Lessie T.G.; RT "Nucleotide sequence of IS402 from Pseudomonas cepacia"; RL Gene 102(1):143-144(1991). XX RN [4] RX PUBMED; 8226615. RA Seibert V., Stadler-Fritzsche K., Schlomann M.; RT "Purification and characterization of maleylacetate reductase from RT Alcaligenes eutrophus JMP134(pJP4)"; RL J. Bacteriol. 175(21):6745-6754(1993). XX RN [5] RP 1-8684 RX PUBMED; 8955303. RA Leveau J.H., van der Meer J.R.; RT "The tfdR gene product can successfully take over the role of the insertion RT element-inactivated TfdT protein as a transcriptional activator of the RT tfdCDEF gene cluster, which encodes chlorocatechol degradation in Ralstonia RT eutropha JMP134(pJP4)"; RL J. Bacteriol. 178(23):6824-6832(1996). XX RN [6] RP 1-8684 RA van der Meer J.; RT ; RL Submitted (01-NOV-1994) to the EMBL/GenBank/DDBJ databases. RL Jan Roelof van der Meer, Department of Microbiology, EAWAG Swiss RL Fed.Inst.for Environmental Sciences and Technology, Ueberlandstrasse, 133, RL Zuerich, CH-8600, Switzerland XX CC On Jan 6, 1997 this sequence version replaced gi:1747422. XX FH Key Location/Qualifiers FH FT source 1..8684 FT /organism="Ralstonia eutropha JMP134" FT /plasmid="pJP4" FT /strain="JMP134" FT /mol_type="genomic DNA" FT /note="synonym: Alcaligenes eutrophus" FT /db_xref="taxon:264198" FT gene 1..687 FT /gene="tfdT" FT CDS 1..687 FT /codon_start=1 FT /transl_table=11 FT /gene="tfdT" FT /product="LysR-type transcriptional regulator" FT /note="inactivated by insertion element ISJP4" FT /db_xref="GOA:P42427" FT /db_xref="InterPro:IPR000847" FT /db_xref="InterPro:IPR005119" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:P42427" FT /experiment="experimental evidence, no additional details FT recorded" FT /protein_id="AAC44724.1" FT /translation="MEIRQLKYFVAVAEAGGFGTAAQRMHISQPPLTRQIQALERDIGA FT KLFERTARGVELTAAGKVFLDDARQLLALVQRSSRRSQAAARGESGELKLVYFGTPVFE FT TVPAFVRTFLATYPDATVAVSHMTKEAQLESLLSGVVDIGFGRFYPVTEGVSSWNIGTE FT TLHVAAADPWDTRVSRARAVVDLLDVPLILYPRGDRPSFADKVVSIFRDRFKKSPGGLL FT TFSASC" FT misc_feature 1..141 FT /gene="tfdT" FT /note="nucleotides 1 to 141 reported previously" FT /citation=[2] FT repeat_region 631..1547 FT /mobile_element="insertion sequence:ISJP4" FT /note="similar to IS402: GenBank Accession Number M64065" FT repeat_region 631..649 FT /rpt_type=INVERTED FT /rpt_unit_seq="agagaccgtttcaaaaaga" FT misc_feature 1476..1547 FT /note="identical to nucleotides 658-729 of 2.1 kB FT BamHI-SalI fragment of pJP4 containing tfdS-tfdA intergenic FT region: GenBank Accession Number M16730" FT /citation=[1] FT repeat_region 1529..1547 FT /rpt_type=INVERTED FT /rpt_unit_seq="tctttttgaaacagtctct" FT CDS complement(1546..2928) FT /codon_start=1 FT /transl_table=11 FT /product="TfdK" FT /function="putative transport protein" FT /db_xref="GOA:Q46M63" FT /db_xref="InterPro:IPR004746" FT /db_xref="InterPro:IPR011701" FT /db_xref="InterPro:IPR016196" FT /db_xref="UniProtKB/TrEMBL:Q46M63" FT /protein_id="AAC44725.1" FT /translation="MNTTIDITDVIEKQSPNRTVGTLLVLSFLIMLCDGYDLQAIAFAS FT PTIIASWGIEKASFGFIFSAGLLGVMLGGFLFGYLADRIGRRPALLLGTFIFSAFTLAA FT VLATNVTELAALRFFAGLGIGGITPICFALNVEYVPKRFHASVVGVVMIGYVIGISVGG FT LFAAWLVPVFGWQVLFYIGGLAPLVLLPILAIALPESIKYLVLAGRGGDTIARIVNAID FT PSAQANAQTRFVLEAEEARAKVGGWKESVKALFRGRLSRITPVLWLAFIANSVTVFFLA FT SWIPVLTVGTGRPATLAAIGLTLFSAGGAFGGLFASRLIDRFGVGAMGAVPLVAAVFVV FT AVGSMAFSDTGFLSMLFIVGFFVLGGHVGLMGSMGLFYANANRANGVGWAISIGKLGSI FT IGPAIAGILIAANASIGTLFMAAAAPLLIAGAGVVLLGRLQKASDLAHATTAGHVADPL FT VS" FT gene complement(3025..4791) FT /gene="tfdBII" FT CDS complement(3025..4785) FT /codon_start=1 FT /transl_table=11 FT /gene="tfdBII" FT /product="chlorophenol monooxygenase" FT /db_xref="GOA:Q46M62" FT /db_xref="InterPro:IPR002938" FT /db_xref="InterPro:IPR003042" FT /db_xref="UniProtKB/TrEMBL:Q46M62" FT /protein_id="AAC44726.1" FT /translation="MNEKANTVETDVLVVGTGPAGAASTLLLATYGVKTLCVSKYATTS FT RTPRSHITNQRTMEVMRDLGIEAECEAMASPAELMGENVYCTSLVGDELGRVLTWGTHP FT QRRADYDLASPTHMCDLPQNLLEPILVNNAARRGADVRFHTEFISLNQDDAGVTATVHD FT HLLDRQYDIRAKYLIGADGANSRIVDQVGLPVEGKMGVSGSINVVFEADLTKYVGHRPS FT VLYWVIQPGSNVGGLGIGVIRMVRPWNKWLCIWGYDIADGTPAVDEAHARQIVHSLLGD FT ATIPVKIESTSTWTVNDMYATRLFDKRVFCMGDAVHRHPPTNGLGSNTSIQDAFNLCWK FT LSHVLRGKAGPELLATYDEERAPVARQVVQRANKSLGDFPPILAALGLFDTKDPEQMQR FT NISRLKEQSVEAQEQRAALRAAIDNTQYVYNAHGVEMNQRYRSAAIVPDETPDPGFRRD FT AELYHDHSSRPGAPLPHVWLTRHGRRVSTLDLCGKGRFTLLSGITGSPWLEAASHAAES FT LGIGLDVHIIGPGQELEDLYGDFARVREIEESGALLVRPDNIICWRAMQWEKSASDPLR FT AALARALCAH" FT gene complement(4853..5932) FT /gene="tfdFII" FT CDS complement(4853..5932) FT /codon_start=1 FT /transl_table=11 FT /gene="tfdFII" FT /product="maleylacetate reductase" FT /db_xref="GOA:P94135" FT /db_xref="InterPro:IPR001670" FT /db_xref="UniProtKB/Swiss-Prot:P94135" FT /citation=[4] FT /protein_id="AAC44727.1" FT /translation="MTGDLNEFVAHFWPVRVVFGAGSTERIPAEVKRLGARRALVLCTP FT DQRDLAQRVLGDLGDLGAGFHDGAVMHVPEASVTRAAQAARDADADLLVAVGGGSTIGL FT AKALALHHGMRFVALPTTYAGSEMTPIWGLTADGAKRTGRDPRVLPSTVLYDPHHLTSL FT PPEVTGPSGMNAIAHAVESMYAPDRNPITMLLAEESIRAMAQGLPVAVDSPGDLDARTR FT TLYAAWLAGTVLGMVSMGLHHKLCHVLGGRFNLPHAPMHAVLLPHVAAFNEVAAPAELG FT RVAAALGAPGPGGAGAALHALLRFTCTERSLAAIGMPAQGIYDAAEHALADAYANPRQA FT SREDIARLLRAAFTGEMPA" FT gene complement(5934..6641) FT /gene="tfdEII" FT CDS complement(5934..6641) FT /codon_start=1 FT /transl_table=11 FT /gene="tfdEII" FT /product="dienelactone hydrolase" FT /db_xref="GOA:P94136" FT /db_xref="InterPro:IPR002925" FT /db_xref="UniProtKB/Swiss-Prot:P94136" FT /protein_id="AAC44728.1" FT /translation="MCHDTAPALFPRTASTGSIDGAICALCYAGATRGPRLLVLPDIYG FT CNAFYRGYAAYLAEQGAGEVLLVDPFAAFGELATVTREAAFQRRHRLADRAYVEELIDF FT IDGQRIEGVVGFCLGGLFVFELARQQVVSRLVAYYPFPQGLENRDPLDVPFDYLPALRS FT RHTVIVGDDDALLGTQNLQRLQAQARANDAIDLHIMNGAGHGFLADLESPDTARAAVAK FT RGLRIGTTTLLGG" FT gene complement(6663..7424) FT /gene="tfdCII" FT CDS complement(6663..7424) FT /codon_start=1 FT /transl_table=11 FT /gene="tfdCII" FT /product="chlorocatechol 1,2-dioxygenase" FT /db_xref="GOA:Q46M59" FT /db_xref="HSSP:1DMH" FT /db_xref="InterPro:IPR000627" FT /db_xref="InterPro:IPR007535" FT /db_xref="InterPro:IPR012817" FT /db_xref="InterPro:IPR015889" FT /db_xref="UniProtKB/TrEMBL:Q46M59" FT /protein_id="AAC44730.1" FT /translation="MTNPRVHEIATAMLDAVRKVLVQQEVTEAEYRAGVMYMMQVAEAK FT EMGLLCDVFLNSTIVEIKAAATRGSAPAIQGPYFKEEAPFVDGKLKTYDSDDHKPLLLH FT GSVKDEAGRVVTDAVIDIWHSTPDGRYSGFGGYHGDMPVDYYRGKVRTDAQGRWRVQTT FT LPAPYQIPNKGPTGALLTMMGSHTWRPAHVHFKVRKDGFEALTTQYYFEGGEWVDSDCC FT NGVKPELVMPAAMEQGMQAMALDFVIEKSRA" FT gene complement(7621..8670) FT /gene="tfdDII" FT CDS complement(7621..8670) FT /codon_start=1 FT /transl_table=11 FT /gene="tfdDII" FT /product="chloromuconate cycloisomerase" FT /db_xref="GOA:P94138" FT /db_xref="HSSP:1BKH" FT /db_xref="InterPro:IPR001354" FT /db_xref="InterPro:IPR013341" FT /db_xref="InterPro:IPR013342" FT /db_xref="InterPro:IPR018110" FT /db_xref="UniProtKB/TrEMBL:P94138" FT /protein_id="AAC44729.1" FT /translation="MLTEKAIADSPNGGDADRKAAQIEAIETVIVDLPLRRIQQFARLG FT AKHQSSVLIRLHTKGGIVGIGESITPCGPWWSGDSVEAIQATINHYLAPLVVGEPALDA FT SRIMAKLHGRVAGNAFAKAGIEMALLDAVGKIVDAPIHVLLGGRFRDRLSVAWPLATGD FT VNQEVDEAFRMLEAGKAGAFKLKMGALPLAQDLRRALAIAKELEGKASLRVDPNEAWDE FT PTTMRALAPLEAAGVEIIEQPVARWNLDAMARIHRQARSMLLIDEGVQSLHDASEVVKR FT AAAGLVSLKIMKTGGMRPARAMADIANAGGMHVYMGTFLETSIGTAANMQLAASIESLP FT TGAKSSGPC" FT misc_feature 7884..8684 FT /note="sequence overlap with Genbank Accession Number FT M98445" XX SQ Sequence 8684 BP; 1481 A; 2790 C; 2869 G; 1544 T; 0 other; atggaaataa gacagttgaa atacttcgtc gcggtcgcgg aggcgggagg tttcggaaca 60 gcggcacaga ggatgcacat atcgcagcca ccgcttactc gtcagatcca ggccttggaa 120 cgcgatattg gggcaaagct tttcgagcgg acggcacggg gcgtcgaact caccgccgcc 180 ggaaaggtgt ttcttgatga cgcgcgtcag ttgctcgcgc ttgtgcagcg gtcttcgcgg 240 cgatcgcaag ctgccgctag aggcgaatcg ggtgagctga agctcgtcta ctttgggact 300 cctgtctttg agacggttcc ggcgttcgtc agaacgttcc tcgcaacgta tcccgacgcc 360 accgtcgccg tgtctcacat gaccaaggaa gctcagctcg agtctcttct ttcaggggtg 420 gtggacatcg gattcgggcg cttctatccg gtgaccgaag gcgtgtcgag ttggaacatt 480 gggacggaga cgcttcacgt cgccgctgcc gatccgtggg acacacgcgt ttcccgtgcc 540 cgtgcagttg tagacctact cgatgtgccc ctcattcttt atccacgcgg cgaccgacca 600 agtttcgccg acaaggtagt ttccatattt agagaccgtt tcaaaaagag ccccgggggg 660 ctgttaacct tttcggcaag ctgttaacct tggccatctg aacaactgga accgagggga 720 tgagcgcgcc gatcattgat gatgaactgt gggcactgat cgaacctttg ctgccgccgc 780 cgaaaccgcg acgcaagaaa tatccagggc ggctcccggt ttcgaaccgg gctgcactga 840 acggcatcct gttcgtgttc aagactggca tacgctggtg cgacctgtcg accaagttgg 900 gattcgggtc ggggccgacc tgctggaggc gcttgcgcga ttggcagaag gccggcgttt 960 ggaagcgatt gcacgagcta ctgctggcga agttacgcga ggccggcgaa ctcgacttct 1020 cccgagcagc cgtcgattca tcgtctgtgc gagccgttgg ggcgggcgaa aaactggtcc 1080 gaaccccacg gatcgctcgc gaccaggttc caagcatcac atcctcgtcg acgcaaatgg 1140 cgtccccatc agcgcaatcc tgaccggggc gaaccgcaac gacgtcaccc aactgctgcc 1200 gctcgtcgac gcgatcccgc caattcgcgg cgtgcgcggt cgcccgcttc aaaagcccaa 1260 agtcatctac gcagaccgtg gctacgactc cgagccgcat cgtcagcggc ttcgcgagcg 1320 cggcatcaaa ccggtgctcg ccaagcgccg gacagaacac ggcagtggct tgggcaaatt 1380 ccgctgggtt gtcgaacgta ctcacgcgtg gcttcacaac tttcgtcgtc ttcgcattcg 1440 cttcgaacgt cgagccgaca ttcacgaagc gttcctaaaa ctcggctgct ctctcgtctg 1500 ctggaacatc ttcaggcgcg ctgagccgtc tttttgaaac agtctctaac tgacaagggg 1560 atcggcaaca tgccctgcgg tggtcgcgtg cgcgaggtcc gaagccttct gaagccggcc 1620 gagcagaacg acaccggcac cggcaatcag cagcggcgcg gcggcagcca tgaagagcgt 1680 gccgatcgag gcgttggccg cgatcaggat gccggcgatg gccgggccga tgatcgatcc 1740 gagcttgccg atggatatcg cccagcccac gccgttggcc cgattggcat tggcgtagaa 1800 caggcccatg gaccccatca ggccgacatg gccgccgagt acgaagaagc cgacgatgaa 1860 gagcatcgac agaaaacccg tgtcggagaa cgccatcgat ccgaccgcga cgacgaagac 1920 cgccgcgacc agcggaaccg cgcccatcgc accgaccccg aacctgtcga tgagccggct 1980 ggcgaacagg ccgccgaatg cgccgcccgc cgagaagagc gtcaggccga tcgcggccag 2040 ggtggcgggc ctgccggttc cgaccgtgag gaccggtatc caactcgcca ggaaaaagac 2100 cgtgacggag ttggcgataa acgcaagcca gaggaccggc gtgatcctgg acaggcggcc 2160 gcgaaagagc gctttcaccg actctttcca cccgcccacc ttggctcggg cttcttcggc 2220 ctcgagaacg aaccgggtct gggcgttcgc ctgcgcggaa gggtcgatgg cattgacgat 2280 ccgcgcgatc gtgtcgccgc ctcggcccgc aagcaccagg tacttgatgg actccggcag 2340 cgcgatggcc agaatcggca gcagcaccag cggcgccaat ccaccgatgt agaacaggac 2400 ctgccagccg aagacaggca cgagccaggc cgcgaagaga ccaccgacgc tgatcccgat 2460 gacgtagccg atcatcacga cgccgacgac gctggcgtgg aagcgcttgg gcacgtactc 2520 gacgttgagc gcgaagcata tcggggtgat gccgccgatg cccagtcccg caaagaagcg 2580 gagtgcggcc agctcggtga cgttggtcgc cagcaccgca gccagcgtga acgcgctgaa 2640 gatgaaagtg ccgagcagaa gcgcgggacg acggccgatc cggtccgcca gatacccgaa 2700 caggaagccg ccgagcatca cgcccagcag tccggcgctg aagatgaagc cgaaggacgc 2760 tttctcgatg ccccagctgg caatgatcgt gggcgacgcg aacgcgatcg cctgcagatc 2820 gtagccgtcg cacagcatga tcaggaacga caggacgagc agcgtgccga ccgtgcggtt 2880 cggcgactgc ttctcgatga cgtcggtgat gtcgatggtg gtgttcatat gtctccttcg 2940 ggcgatggtg atcggcgttt tgcgggcgtg cacgtgccgg cgtgccgccg cctggccacg 3000 cttgccgatc gggtttttct ggagtcagtg cgcgcagagc gcccgtgcga gcgccgcgcg 3060 aagcgggtcg ctcgcgctct tttcccactg catcgctcgc cagcagatga tgttgtcggg 3120 gcgcacgagc aatgcgccgc tctcctcgat ctcgcgaaca cgggcgaaat cgccgtacag 3180 gtcctcgagt tcctggccgg ggccgatgat gtgcacgtcc aggccgatgc cgagcgactc 3240 cgcggcatgg ctcgcggcct cgagccaggg cgatccggtg atgcccgaga gcagggtgaa 3300 ccggcccttg ccgcaaagat cgagcgtcga tacgcggcgg ccgtggcgcg tgagccagac 3360 gtgcggcagg ggcgcgccgg gtcggctgct gtggtcgtgg tagagctccg cgtcgcggcg 3420 gaatcccggg tccggtgtct cgtccggaac gatcgccgcc gaccgatagc gctggttcat 3480 ctcgacgccg tgggcgttgt agacgtactg cgtgttgtcg atggcagcgc gcaatgcggc 3540 gcgctgttcc tgcgcctcca cgctctgttc cttcaggcgg gagatgttgc gctgcatctg 3600 ttcggggtcc ttcgtgtcga acaggcccag cgcggcgagg atcggcggga agtccccgag 3660 gctcttgttc gcgcgttgca ccacctgcct ggcgaccggc gcacgctcct cgtcgtaggt 3720 ggcgagcagt tccgggccgg cctttcctcg aagcacgtgc gagagtttcc agcagaggtt 3780 gaaggcgtcc tggatcgacg tgttcgagcc caggccgttg gtcggcgggt gccgatggac 3840 cgcgtcgccc atgcagaaca cccgcttgtc gaacagccgc gtggcgtaca tgtcgttcac 3900 cgtccaggtc gaggtcgatt cgatcttgac cgggatcgtc gcgtcgccca acagcgaatg 3960 gacgatctgg cgcgcatgcg cttcgtcgac ggccggggtg ccatcggcga tgtcgtagcc 4020 ccagatgcaa agccacttgt tccacggccg caccatgcga atgacgccga tgccgaggcc 4080 gccgacattg gagccgggct ggatgaccca atacagcacg ctcggccgat ggcccacgta 4140 cttcgtgagg tccgcctcga acacgacgtt gatggagccg gagacgccca tcttcccttc 4200 caccggcagg ccgacctggt ccacgatccg ggaattcgcg ccatccgcgc cgatgaggta 4260 tttggcccgg atgtcgtact ggcgatccag caggtggtcg tgcacggtcg ccgtgacgcc 4320 cgcatcgtcc tggttcaacg agatgaactc ggtgtgaaag cgcacgtcgg caccgcgccg 4380 cgccgcgttg ttgacgagga tcggttcgag caggttctgc ggcaggtcgc acatgtgcgt 4440 gggcgaagcg aggtcgtagt cggcccggcg ctgcggatgc gtgccccagg tcagcacgcg 4500 gcccagttcg tcgccgacga ggctcgtgca atagacgttc tcgcccatca gctcggccgg 4560 cgaggccatg gcctcgcact ccgcctcgat gccgaggtcg cgcatcacct ccatcgttcg 4620 ctggttggtg atgtgcgagc gcggggtgcg cgacgtggtc gcgtatttgc tgacgcacag 4680 cgtcttcacc ccgtaggtcg cgagaagcag ggtcgacgcc gccccggcgg gaccggtgcc 4740 gacgacgaga acgtcggttt cgacggtgtt ggctttttcg ttcatgaagt ctccttatcg 4800 ataggtcggg tcgctcgcat cgtcgacgcg agaggtccat gggatgtccg gttcacgccg 4860 gcatttctcc ggtgaaagcg gctcgcagca ggcgagcgat gtcttcgcgg ctcgcctggc 4920 gtggattcgc ataggcatcg gcgagcgcgt gttccgcggc gtcgtagatg ccttgcgccg 4980 gcatgccgat ggccgccagc gatctttccg tgcaagtgaa tcgcagcaat gcatgcaagg 5040 ccgcgccggc gccgccgggc cccggcgcgc cgagtgcggc cgcgacgcgt ccgagttccg 5100 cgggcgcagc cacctcgttg aaggccgcca cgtgaggcaa caacacggcg tgcatcggcg 5160 catgcggcag gttgaatcgc cccccgagca catggcagag cttgtggtgc aggcccatcg 5220 agaccatgcc cagtaccgtt cccgcgagcc aggcggcata gagcgtgcgc gtgcgcgcat 5280 cgagatcgcc gggcgagtcg acggcgacgg gcagtccctg cgccatcgcg cgaatgcttt 5340 cttcggccag cagcatggtg atcgggttgc ggtccggggc gtacatcgac tccacggcgt 5400 gcgcgatcgc gttcatgccg ctcgggccgg tgacctccgg cggcaaggag gtcaggtgat 5460 gcgggtcgta gaggacggtg ctgggcagca cgcgaggatc ccggcccgtg cgcttcgcgc 5520 catcggcggt caagccccag atgggcgtca tctccgaacc cgcataggtc gtcggcaagg 5580 cgacgaagcg cattccgtga tgaagcgcga gcgccttggc cagtccgatg gtcgagccgc 5640 cgccgaccgc cacgagcagg tccgcgtcgg cgtcccgggc cgcttgcgcg gcgcgcgtga 5700 ccgacgcctc gggcacgtgc atgacggcgc cgtcatggaa gcccgcgccc aggtcgccga 5760 gatcgccgag cacccgctgc gccagatcgc gctggtccgg cgtgcagagc accagtgcgc 5820 gtcgtgcacc caggcgcttg acctccgcgg ggatccgttc ggtcgatcca gcgccgaaga 5880 cgaccctgac cggccagaag tgcgcaacga attcattcag atcgccggtc acttcagccc 5940 cccaacaagg tcgtcgtacc gatgcgcagt ccgcgcttcg ccacggccgc gcgcgccgtg 6000 tccggcgatt cgagatctgc caggaagccg tggccggcac cgttcatgat gtgcaggtcg 6060 atcgcatcgt tggcgcgggc ttgtgcttgc aaccgctgca ggttctgtgt acccagcagc 6120 gcatcgtcgt ctcccacgat gaccgtatgc cgcgaacgaa gcgccggcag atagtcgaac 6180 ggaacgtcca gcgggtcgcg gttctcgagc ccctgcggaa acgggtaata agcgacgagc 6240 cgcgacacga cctgctgtcg cgccagttcg aacacgaaga ggccaccgag acagaagccg 6300 accacgccct cgatgcgctg gccgtcaatg aagtcgatca attcctcgac gtaggcacga 6360 tccgccagtc ggtgacgtcg ctggaaggcc gcttcccgcg tcactgtggc caattcgccg 6420 aacgccgcaa agggatcgac caggagcacc tcgccggcgc cttgctctgc caggtacgcg 6480 gcatagccac ggtagaaggc attgcagcca tagatgtccg gcagcacgag aaggcgcggt 6540 ccccttgtcg cgccggcgta gcacaaggcg cagattgcac cgtcgatgct ccccgtggat 6600 gcggtccgcg ggaacaacgc gggggcggtg tcgtggcaca tgggtggctg gccttcgccg 6660 tctcaggcgc gggacttctc gatgacgaag tccagtgcca tcgcctgcat gccttgctcc 6720 atggctgccg gcatcacgag ttcgggcttg acgccgttgc agcagtcgct gtcgacccac 6780 tcgccgcctt cgaagtagta ctgcgtcgtc agtgcctcga agccgtcctt gcggaccttg 6840 aagtgaacgt gcgcagggcg ccaggtgtgg cttcccatca tggtgagcag ggcgccggtc 6900 ggccccttgt tcgggatctg atagggcgcc ggcaacgtgg tctgcacgcg ccaccggcct 6960 tgcgcgtccg tgcggacctt gccccggtag tagtcgaccg gcatgtcgcc gtggtagccg 7020 ccgaatccgc tgtagcggcc gtccggcgtc gagtgccaga tgtcgatgac cgcatcggtc 7080 acgacgcgcc cggcttcgtc cttcacgctt ccatgcagaa gcagcggctt gtggtcgtcg 7140 ctgtcgtagg tcttgagctt gccgtcgacg aagggcgctt cctccttgaa gtacggcccc 7200 tggatggcgg gcgccgatcc gcgcgtggcg gcggccttga tctcgacgat cgtgctgttg 7260 aggaagacat cgcagagcag gcccatttcc ttggcctcgg cgacctgcat catgtacatc 7320 acccccgctc gatactctgc ttcggtcact tcttgctgga ccaggacctt gcgcacggca 7380 tcgagcatgg cggtggcgat ctcatggacg cggggatttg tcatggtgct ttctcttcaa 7440 aaaagatgaa tcgggtggat gtggcgcgtc aggcgctgtg acgatcgatg cgctgggacg 7500 aagcacgcgc gaagcgccgc acctggttct cgtcgagtcg gattccgagg cccgggcctt 7560 cggggagcca cagggcatgt tccttgtaga ccgcggggac ttcgcacagg tcctcctcga 7620 tcagcaaggg cccgatgact tcgcccccgt aggcagcgac tcgatcgatg cagccagttg 7680 catgttggcg gccgtgccta tcgaggtctc cagaaaggtg cccatgtaca cgtgcatgcc 7740 tccggcattg gcgatgtcgg ccatcgcgcg tgcagggcgc atcccgccgg tcttcatgat 7800 cttcagcgat accagaccgg ccgcggcccg cttcacgacc tcgctcgcgt cgtgcaggga 7860 ttgcacaccc tcgtcgatca gcagcatgct tcgcgcttgc cggtggatgc gggccatcgc 7920 atcgagattc cagcgggcga cgggctgctc gatgatttcc acgccggccg cctccagggg 7980 cgccagtgcc cgcatcgtgg tcggctcgtc ccacgcttcg ttgggatcga cgcgcaggct 8040 cgccttgccc tcgagttcct tcgcgatcgc caatgcacgc cgcaggtctt gcgccagcgg 8100 cagcgcgccc atcttcagtt tgaaggcccc ggccttgcct gcctccagca tgcggaacgc 8160 ctcgtcgacc tcctggttca cgtcgcccgt ggcgagcggc catgcgacgc tgagccggtc 8220 gcgaaagcgt cctcccagca agacgtggat cggggcatcg acgatcttgc cgaccgcgtc 8280 cagcagtgcc atctcgatgc cggccttggc gaaggcattg ccggccacgc ggccatggag 8340 cttcgccatg atgcgcgacg catcgagcgc cggttcgccg acgacgagag gcgccaggta 8400 gtggttgatc gtggcttgaa tggcttcgac gctgtcgccg ctccaccagg gaccgcaggg 8460 cgtgatggac tcaccgatcc cgacgatgcc gcccttcgta tggagacgga tgagcacgct 8520 gctctgatgc ttggcgccca ggcgggcgaa ctgctggatg cggcgcagcg gcagatcgac 8580 gatcaccgtt tcgatcgctt cgatctgcgc cgccttgcga tcggcgtcgc cgccgttggg 8640 gctgtcggca atggcttttt ctgtgagcat ggcggtagtc taga 8684 // |
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