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EBI DbfetchID U05193; SV 1; linear; mRNA; STD; VRT; 4716 BP. XX AC U05193; XX DT 31-MAR-1994 (Rel. 39, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 6) XX DE Rana catesbeiana carbamyl phosphate synthetase mRNA, complete cds. XX KW . XX OS Rana catesbeiana (bullfrog) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Aquarana. XX RN [1] RP 1-4716 RX PUBMED; 8163471. RA Helbing C.C., Atkinson B.G.; RT "3,5,3'-Triiodothyronine-induced carbamyl-phosphate synthetase gene RT expression is stabilized in the liver of Rana catesbeiana tadpoles during RT heat shock"; RL J. Biol. Chem. 269(16):11743-11750(1994). XX RN [2] RP 1-4716 RA Helbing C.C.; RT ; RL Submitted (14-JAN-1994) to the EMBL/GenBank/DDBJ databases. RL Caren C. Helbing, Zoology, University of Western Ontario, Western Science RL Centre, London, Ontario, N6A 5B7, Canada XX FH Key Location/Qualifiers FH FT source 1..4716 FT /organism="Rana catesbeiana" FT /mol_type="mRNA" FT /dev_stage="thyroid hormone-induced" FT /tissue_type="liver" FT /db_xref="taxon:8400" FT CDS 33..4523 FT /codon_start=1 FT /product="carbamyl phosphate synthetase" FT /db_xref="GOA:Q91293" FT /db_xref="HSSP:1M6V" FT /db_xref="InterPro:IPR013817" FT /db_xref="UniProtKB/Swiss-Prot:Q91293" FT /protein_id="AAA19016.1" FT /translation="MTRILSVFKTAKTGVLNAAAHRYRGFSKAGVRLMSVKAQTANLVL FT EDGTKIKGYSFGHPASVAGEVIFNTGLGGYVEAVTDPSYHGQILTLTNPIIGNGGAPDT FT KARDAYGLMKYIESENIQASGLLVLDYSHEYSHWGAVKSLSEWLHEEKVPALCGIDTRM FT LAKKIRDNKGAVLGKIEFEGQPVEFIDPNKRNLIAEVSTKETKVFGKGNPVRIVAVDCG FT VKHNIIRQLVKRGAEVHLVPWNHDFSQMEYDGLLITSGPGNPELAKPLIQNLKKVFQSD FT RPEPIFGICKGNEIAALAAGGKTYRLPMANRGQNQPVMITLNGQAFITAQNHAYAVDNN FT SLPAGWKPLFVNINDQSNEGIMHETKPIFTSQFHPEANPGPVDTEFLFDVYMSLIKKGK FT GTTLTSVMPKPALQSKRIDVAKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVL FT MNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEKTDGIILGMGGQTALNCGVEL FT FKRGVLKEYGVRVLGTSVESIMFTEDRQLFSDKLNEIKEPIAPSFAVESVKDALEAADK FT IGYPVMIRSAYALGGLGSGLCPDKETLTDLATKALAMTNQILVERSVVGWKEIEYEVVR FT DAADNCVTVCNMENVDAMGVHTGDSIVVAPCQTLSNEECQMLRAVSIKVVRHLGIVGEC FT NIQFALHPTSLEYVIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSG FT KTTACFEPSLDYMVTKIPRWDLDRFHGASGLIGSSMKSVGEVMAIGRTFEESFQKALRM FT CHPSVDGFTSNLPMNKAWSSDVNLRKEMAEPTSTRMYSMAKAIQSGISLDEINKLTAID FT KWFLYKMQGILNMEKTLKGSRSESVPEETLRRAKQIGFSDRYIGKCLGLSETQTRELRL FT NKNVKPWVKQIDTLAAEYPAITNYLYLTYNGQEHDIKFDDHGMMVLGCGPYHIGSSVEF FT DWCAVSSIRTLRHVGKKTVVVNCNPETVSTDFDECDKLYFEELSQERIMDVFQLEQCDG FT CIISVGGQIPNNLAVPLYKNGVKIMGTSPMQIDRAEDRSIFSAVLDELQIAQAPWKAVN FT SLDDALQFTKTVGYPCLLRPSYVLSGSAMNVVYGEEELKTFLAEATRVSQEHPVVITKF FT IEGAREVEMDAVGKEGRVISHAISEHVEDAGVHSGDATLMIPTQSISQGAIEKVKIATK FT KIATAFAISGPFNVQFLVRGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGEK FT IDESSLPTLERPVIPADYVGIKAPMFSWPRLRGADPVLKCEMASTGEVACFGQNVYSAF FT LKAMISTGFKLPQKGILIGIQHSFRPHFLGTAQTLKDEGFKLYATEATADWLNANDITA FT TPVAWPSQEGQSGPSSIYKLIKEGNIDMVINLPNNNTKYVRDNFAIRRTAVDTGTALLT FT NFQVVKMFAEAIKYSGDLDAKSLFHYRQFGGAKPS" FT mat_peptide 132..4523 FT /product="carbamyl phosphate synthetase" FT misc_feature 900..902 FT /note="encodes a cysteine at AA 290, like microbial CPS II FT and mammalian CAD, a nucleotide transversion results in a FT serine codon found in mammalian CPS I" FT polyA_site 4699 FT /note="one clone had a poly-A tail following 4716 whereas FT another continued for an additional 515 nucleotide and did FT not possess a poly-A tail" XX SQ Sequence 4716 BP; 1321 A; 1033 C; 1143 G; 1219 T; 0 other; gctgaacaga acagcacctc agggccccaa acatgactcg gattttgtct gtgtttaaga 60 cagcaaagac aggggttctc aatgcagcag cccatcgtta ccggggcttc tccaaagccg 120 gcgttcggct tatgagcgtc aaggcacaaa ctgctaattt agtgttggaa gatggcacaa 180 aaatcaaagg atattcgttt gggcaccctg catcggttgc cggtgaggtc atctttaaca 240 ctggtttggg cggatatgta gaagctgtga cagatccaag ctatcatggt cagattctca 300 ctcttaccaa cccaataatt ggaaatggcg gtgcacccga taccaaggcc cgtgatgcct 360 atggccttat gaaatacatt gagtctgaga atatccaggc atctggtctg ctagtgctcg 420 attacagtca tgagtacagt cactgggggg cagtcaagtc actatctgaa tggctgcatg 480 aagaaaaggt tcctgcactt tgtgggattg ataccagaat gcttgcaaaa aagatcagag 540 acaacaaggg agctgtactg ggtaaaattg aatttgaagg ccaacctgtg gaatttattg 600 acccaaacaa aagaaacctt attgcagaag tgtccacaaa ggaaaccaaa gtatttggca 660 aagggaatcc tgtcagaatc gtggcagtag actgtggagt aaagcataac atcatccgtc 720 agttggtaaa gagaggggca gaggtacacc ttgtcccttg gaatcatgac ttctctcaga 780 tggaatatga tggtctccta attacaagtg gccctggaaa cccagagtta gcaaagcctc 840 taatacaaaa tctcaagaag gtcttccaga gcgaccgtcc tgagcctata tttggcatct 900 gtaaagggaa tgaaattgca gctttggcag ctggtggcaa gacgtatagg ctgcccatgg 960 ctaacagagg gcagaaccaa cctgttatga tcaccttgaa tggccaagct ttcattactg 1020 ctcagaacca tgcctatgca gtggataaca attctctacc tgcaggctgg aaaccacttt 1080 ttgtaaacat caatgaccag agcaatgagg ggattatgca tgagaccaaa ccaatcttca 1140 cttcgcaatt ccaccctgag gctaaccctg ggcctgttga cacagagttc ctatttgatg 1200 tctacatgtc actgataaag aagggtaaag gtaccaccct gacatctgta atgcccaaac 1260 cagctctgca gtctaaacga attgatgtag ctaaagttct catcctgggc tctggaggtc 1320 tctctattgg gcaagcagga gagtttgatt attctgggtc acaggcagtt aaagctatga 1380 aagaagaaaa tgtgaaaaca gttcttatga accccaacat tgcctctgtc cagactaatg 1440 aggttggcct caagcaagct gacacagtct acttcctacc catcacacca cagtttgtca 1500 ccgaagtcat taaggcagaa aagactgacg gaattatctt gggaatgggt ggacagacag 1560 ctctgaactg cggtgtggaa cttttcaaac gaggggtact caaggaatac ggagtacggg 1620 ttttgggcac ctcagtggag tccatcatgt ttacagaaga cagacagctc ttctctgaca 1680 aactaaatga aattaaggaa cctattgccc ccagttttgc tgtggaatcg gtgaaagatg 1740 ctttggaagc agcagataaa attggctatc ctgtcatgat tcgatctgcc tatgccttag 1800 gtggtctggg gtcaggactt tgtcctgaca aggaaacact cacagacctg gcaacaaagg 1860 ctctggcaat gaccaaccag atcttggtgg aacgttcagt tgtaggctgg aaagagattg 1920 agtatgaggt agttagagat gcagcagata actgtgttac cgtctgcaac atggaaaatg 1980 ttgatgctat gggggtccat acaggggact ccatagttgt cgctccttgc cagactttgt 2040 ccaatgagga gtgtcagatg ctgagagcag tctccatcaa agttgtacgc cacttgggta 2100 ttgttggaga atgtaatata cagtttgctc ttcatccaac ctcactggag tatgtcatca 2160 ttgaagtcaa tgctcgactc tctcgtagtt cagctttggc atccaaagcc actggctacc 2220 ctctggcctt cattgctgcc aaaattgcct tgggaattcc tttgccagaa attaaaaatg 2280 ttgtatcagg gaagaccact gcttgctttg agcccagtct agactacatg gtgaccaaga 2340 tacctcgttg ggatttggac cgtttccatg gtgcttcagg attaattggc agctcaatga 2400 aaagtgtagg agaggttatg gccattggtc gaacctttga ggaaagcttt cagaaagccc 2460 tgaggatgtg ccacccatca gtagatggct ttacatcaaa tcttccaatg aacaaagcgt 2520 ggtcatcaga tgtcaaccta aggaaagaga tggccgaacc cacaagtacc cgtatgtaca 2580 gcatggccaa ggctatacaa agtggaattt ccttagatga aatcaacaaa ctgacagcta 2640 ttgataagtg gttcctgtac aagatgcaag gaatcctcaa catggagaag actttgaaag 2700 gaagcagaag tgaatctgta ccagaggaaa cactgcggag ggccaagcag attgggtttt 2760 ctgatcgtta tattgggaag tgtctggggc tctctgaaac tcaaaccaga gagcttagat 2820 tgaacaagaa tgtcaagcct tgggttaaac agattgatac tttggctgct gagtatccag 2880 caattacaaa ctacctctac ctcacctaca atggacagga gcatgatata aagtttgatg 2940 accacggaat gatggttcta ggttgtggcc cgtatcatat aggcagcagt gtagagtttg 3000 attggtgtgc cgtttccagc atccgcacat tgcgtcacgt cggcaagaaa acagtggtgg 3060 tgaactgcaa ccctgagact gtcagcacag actttgatga gtgtgacaaa ctttactttg 3120 aagagctgtc acaggaaaga atcatggatg tgttccaact ggagcaatgt gatggctgca 3180 tcatctctgt tggggggcag atccccaaca acttggctgt gccattgtac aagaacgggg 3240 tgaagattat gggtaccagt cccatgcaga ttgatcgggc agaagatcga tccatattct 3300 cagctgttct ggacgagctt cagattgcac aggctccatg gaaagctgtc aattctctgg 3360 atgatgcttt gcagtttaca aagactgttg ggtatccatg cttgctgcgt ccctcctatg 3420 tgctcagtgg ctcagcaatg aatgtagtat atggagagga ggaactgaag actttcctag 3480 ctgaagcgac acgtgtttca caggagcacc ctgttgtgat caccaagttt atcgaaggtg 3540 cccgagaggt ggagatggat gcagttggca aggaagggcg tgtcatctcc catgctattt 3600 ctgagcatgt tgaggatgct ggagttcatt ctggagatgc caccctcatg atccccacac 3660 agtcaatcag ccagggagca atagagaaag tgaaaattgc taccaagaaa attgcaaccg 3720 cttttgctat ttctggaccc ttcaatgtgc agttccttgt tagaggaaat gatgttctgg 3780 taattgaatg caacctgaga gcttctcgat ccttcccatt tgtgtccaag actttgggcg 3840 ttgacttcat tgatgtggcc acaaaagtta tgattggaga aaaaattgat gaatcttccc 3900 taccaacatt agagagacct gttatccctg ctgattatgt gggcatcaag gctcccatgt 3960 tttcctggcc ccgccttaga ggagctgatc cagttctgaa atgtgagatg gcttcgactg 4020 gtgaggtggc ctgctttgga caaaacgtct actctgcatt cctgaaggcc atgatctcca 4080 ctggcttcaa gctgcctcag aagggaattc tcattggaat ccagcattcc ttccggcccc 4140 acttccttgg aactgcccaa acactcaaag acgaaggatt caagctatat gctaccgagg 4200 ccactgcaga ctggctcaat gcaaatgata tcactgccac ccctgttgct tggccctccc 4260 aggaaggaca atctggacct tcttcaatat acaagttgat taaagaaggc aacattgaca 4320 tggtgatcaa cttgccaaac aacaacacca aatatgtacg tgataacttt gcgatacgga 4380 ggactgctgt agacactggc accgctttac tcaccaactt ccaggtggtc aaaatgttcg 4440 ctgaagctat taaatactct ggagacctgg atgccaagag ccttttccac tacagacagt 4500 ttggtggcgc caaaccctcc tagagatctg aactattcac aagcagcttt ctcaattaag 4560 agactgctga ccgcctaagg tcttctgctg gttttctgtt tactgtcact tgtgtctaag 4620 cttgtatgaa gaacacaaat gtctatttga ttatgtcttt gcagttatga acatgtggat 4680 gctagaatgt tttggtacat aaataattat actttt 4716 // |
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