EBI Dbfetch

ID   M90083; SV 1; linear; genomic DNA; STD; PRO; 1054 BP.
XX
AC   M90083;
XX
DT   23-OCT-1992 (Rel. 33, Created)
DT   17-APR-2005 (Rel. 83, Last updated, Version 6)
XX
DE   Methanothermus sociabilis porphobilinogen synthase (aladh) gene, complete
DE   cds.
XX
KW   5-aminolevulinic acid dehydratase; aladh gene; porphobilinogen synthase;
KW   Zn-binding protein.
XX
OS   Methanothermus sociabilis
OC   Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales;
OC   Methanothermaceae; Methanothermus.
XX
RN   [1]
RP   1-1054
RX   DOI; 10.1016/0378-1119(92)90084-3
RX   PUBMED; 1398086.
RA   Broeckl G., Berchtold M., Behr M., Koenig H.;
RT   "Sequence of the 5-aminolevulinic acid dehydratase-encoding gene from the
RT   hyperthermophilic methanogen, Methanothermus sociabilis";
RL   Gene 119(1):151-152(1992).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1054
FT                   /organism="Methanothermus sociabilis"
FT                   /strain="KF1-Fl"
FT                   /mol_type="genomic DNA"
FT                   /tissue_lib="DSM 34966"
FT                   /db_xref="taxon:2181"
FT   RBS             19..23
FT                   /gene="aladh"
FT   gene            19..993
FT                   /gene="aladh"
FT   CDS             31..993
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="aladh"
FT                   /product="porphobilinogen synthase"
FT                   /function="condensation of two 5-aminolevulinic acid
FT                   molecules to porphobilinogen"
FT                   /EC_number="4.2.1.24"
FT                   /db_xref="GOA:Q02250"
FT                   /db_xref="InterPro:IPR001731"
FT                   /db_xref="InterPro:IPR013785"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q02250"
FT                   /protein_id="AAA73226.1"
FT                   /translation="MKFPYTRMRRLRKNSKIRSLVKETTLSKDDLIYPVFVKEGIKTKE
FT                   KIPKMPGQYRYSVDELIDEAKKLEEKGLKAILVFGIPKKKDKYGSSAYDPNGIVQKSVK
FT                   LLKEETDLVVITDVCLCQYTEHGHCGIVKNKKIVNDETLKYLSKVALSHAEAGADVVAP
FT                   SDMMDGRVKAIREELEKNGFDDVIIMSYSAKYASSFYEPFRSAVYSSPAFGDRSTYQMD
FT                   PPNSLEALREVKLDIDEGADIVMVKPALPYLDIIRLVKDTFGVPTAAYNVSGEYSMIKA
FT                   AIDANYLSNKVIIETLLSIKRAGADLIITHFAPEIVEEI"
FT   misc_binding    118..131
FT                   /gene="aladh"
FT                   /bound_moiety="Zn"
FT   misc_feature    247..251
FT                   /gene="aladh"
FT                   /note="active site"
XX
SQ   Sequence 1054 BP; 402 A; 150 C; 192 G; 310 T; 0 other;
     tatttctacg acttcatcag gtgtattaaa atgaaatttc catacactcg gatgagaagg        60
     ttaagaaaaa attctaaaat aaggtctcta gtgaaagaga ctactttatc caaagatgat       120
     ttgatatatc ctgtttttgt aaaagaaggt ataaaaacca aggaaaaaat tcctaaaatg       180
     ccaggacaat ataggtactc tgtcgatgaa ttaatagatg aggctaaaaa gctagaagaa       240
     aaaggattaa aagctatatt agtttttgga attccgaaaa aaaaagataa atatggatcc       300
     agcgcttatg acccaaatgg cattgtccaa aaatctgtaa aattattaaa agaagagaca       360
     gacttagtag taataaccga tgtatgtctt tgtcaatata ctgaacatgg acattgcgga       420
     atagttaaaa acaaaaaaat agtaaacgat gaaactctca aatatttatc taaagtagct       480
     ttatcacatg ctgaagctgg tgcagatgtt gttgcaccat cagacatgat ggatggtcgt       540
     gtaaaggcta taagggaaga attagaaaaa aatggttttg atgatgtaat aataatgtca       600
     tattcagcaa aatacgcgtc atctttttat gaaccattca gatcagcagt atattcatct       660
     ccagcatttg gagatagaag tacttaccaa atggatccac cgaactcttt agaagctcta       720
     agggaagtca aattagatat tgatgaaggc gccgacatcg taatggtaaa acctgcttta       780
     ccttatcttg atattattag acttgttaaa gatacttttg gagtacctac tgccgcatat       840
     aatgtaagtg gtgaatattc aatgataaaa gccgctatag atgcaaatta tctttctaat       900
     aaagttataa tagaaacatt gctttccata aaacgtgcag gtgcagattt aataatcaca       960
     cattttgctc ctgaaattgt ggaggaaata taagctatga atgctaatta tgtttcaaaa      1020
     tcagcgcaaa tagcatcaat attagaagtt agtg                                  1054
//