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EBI DbfetchID M88334; SV 1; linear; genomic DNA; STD; PRO; 5378 BP. XX AC M88334; M38417; XX DT 16-MAR-1992 (Rel. 31, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 7) XX DE Escherichia coli succinic semialdehyde dehydrogenase (gabD), GABA DE transaminase (gabT), and GABA permease (gabP) genes, complete cds. XX KW GABA permease; GABA transaminase; gabD gene; gabP gene; gabT gene; KW succinic semialdehyde dehydrogenase. XX OS Escherichia coli OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. XX RN [1] RP 1826-3433 RX PUBMED; 2254272. RA Bartsch K., von Johnn-Marteville A., Schulz A.; RT "Molecular analysis of two genes of the Escherichia coli gab cluster: RT nucleotide sequence of the glutamate:succinic semialdehyde transaminase RT gene (gabT) and characterization of the succinic semialdehyde dehydrogenase RT gene (gabD)"; RL J. Bacteriol. 172(12):7035-7042(1990). XX RN [2] RP 1-5378 RX DOI; 10.1007/BF00245306 RX PUBMED; 8297211. RA Niegemann E., Schulz A., Bartsch K.; RT "Molecular organization of the Escherichia coli gab cluster: nucleotide RT sequence of the structural genes gabD and gabP and expression of the GABA RT permease gene"; RL Arch. Microbiol. 160(6):454-460(1993). XX RN [3] RP 1826-3433 RA Bartsch K.; RT ; RL Submitted (10-SEP-1990) to the EMBL/GenBank/DDBJ databases. RL Klaus Bartsch, Hoechst AG H 872N, Biologische Forschung Bereich C, 6230 RL Frankfurt 80, FRG XX RN [4] RP 1-5378 RA Bartsch K.; RT ; RL Submitted (15-MAR-1992) to the EMBL/GenBank/DDBJ databases. RL Klaus Bartsch, Hoechst AG H 872N, Biologische Forschung Bereich C, 6230 RL Frankfurt 80, FRG XX DR GOA; P37338. DR GOA; P37339. DR InterPro; IPR000524; HTH_GntR. DR InterPro; IPR006076; FAD-dep_OxRdtase. DR InterPro; IPR011711; GntR_C. DR InterPro; IPR011991; Wing_hlx_DNA_bd. DR InterPro; IPR015657; Aminobutyraldehyde_DH. DR UniProtKB/Swiss-Prot; P37338; YGAE_ECOLI. DR UniProtKB/Swiss-Prot; P37339; YGAF_ECOLI. XX CC On Feb 8, 2002 this sequence version replaced gi:146053. XX FH Key Location/Qualifiers FH FT source 1..5378 FT /organism="Escherichia coli" FT /map="57.6 min" FT /strain="K12" FT /mol_type="genomic DNA" FT /db_xref="taxon:562" FT CDS 638..2086 FT /codon_start=1 FT /transl_table=11 FT /gene="gabD" FT /product="succinic semialdehyde dehydrogenase" FT /EC_number="1.2.1.16" FT /db_xref="GOA:P25526" FT /db_xref="InterPro:IPR010102" FT /db_xref="InterPro:IPR015590" FT /db_xref="InterPro:IPR016160" FT /db_xref="InterPro:IPR016161" FT /db_xref="InterPro:IPR016162" FT /db_xref="UniProtKB/Swiss-Prot:P25526" FT /protein_id="AAC36831.1" FT /translation="MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKM FT GADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAE FT AKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMI FT TRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTS FT NPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASK FT FRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLDNGVTIGPLIDEKAVAKV FT EEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKD FT EADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKAS FT GLGREGSKYGIEDYLEIKYMCIGL" FT CDS 2100..3380 FT /codon_start=1 FT /transl_table=11 FT /gene="gabT" FT /product="GABA transaminase" FT /EC_number="2.6.1.19" FT /db_xref="GOA:P22256" FT /db_xref="InterPro:IPR004632" FT /db_xref="InterPro:IPR005814" FT /db_xref="InterPro:IPR015421" FT /db_xref="InterPro:IPR015424" FT /db_xref="PDB:1SF2" FT /db_xref="PDB:1SFF" FT /db_xref="PDB:1SZK" FT /db_xref="PDB:1SZS" FT /db_xref="PDB:1SZU" FT /db_xref="UniProtKB/Swiss-Prot:P22256" FT /protein_id="AAC36832.1" FT /translation="MNSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYLD FT FAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFAKK FT TLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMGLMP FT GHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYASSPAFM FT QRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPLAGVTG FT RAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDGLLAIAE FT KHPEIGDVRGLGAMIAIELFEDGDHNKPDAKLTAEIVARARDKGLILLSCGPYYNVLRI FT LVPLTIEDAQIRQGLEIISQCFDEAKQ" FT CDS 3616..5016 FT /codon_start=1 FT /transl_table=11 FT /gene="gabP" FT /product="GABA permease" FT /db_xref="GOA:P25527" FT /db_xref="InterPro:IPR002293" FT /db_xref="InterPro:IPR004840" FT /db_xref="InterPro:IPR004841" FT /db_xref="InterPro:IPR011265" FT /db_xref="UniProtKB/Swiss-Prot:P25527" FT /protein_id="AAC36833.1" FT /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAGP FT AVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFWVL FT VIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAI FT LAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTI FT AAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSVLELLN FT IPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAVLL FT STGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAEGSEIRLR FT MWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMARWKKLVLWQ FT KTPVHNTR" XX SQ Sequence 5378 BP; 1151 A; 1442 C; 1579 G; 1206 T; 0 other; atctgcccgt tccgtggcga gtatttccgc cttgcgccgg agcataacca gattgttaac 60 cacctgattt accccattcc cgacccggca atgccgtttt tgggcgttca tctcacccgc 120 atgatcgacg gcagcgtgac cgtcgggcca aacgcggtgc tggctttcaa acgcgaaggc 180 tatcgcaagc gcgacttctc atttagcgac acgctggaga ttttgggctc gtcggggatt 240 cgccgggtgc tgcaaaacca tctacgctca ggactgggcg agatgaaaaa ctcgctgtgc 300 aaaagcggct atctgcggct ggtgcaaaag tattgtcccc ggctttcgtt aagcgatctc 360 cagccctggc ccgccggtgt gcgggcgcag gcggtatcgc cggacggcaa gctgattgac 420 gattttctgt ttgtcaccac cccgcgcacg atccacacct gcaatgcgcc ctccccggca 480 gcgacatcag caattcctat tggtgcgcat attgtcagca aggtacaaac gctgttggca 540 agccagagta accccggacg cacgctgcga gcggcacgta gtgtggatgc cttacacgcc 600 gcatttaatc aataaccttt gaaaacagga tgtagcgatg aaacttaacg acagtaactt 660 attccgccag caggcgttga ttaacgggga atggctggac gccaacaatg gtgaagccat 720 cgacgtcacc aatccggcga acggcgacaa gctgggtagc gtgccgaaaa tgggcgcgga 780 tgaaacccgc gccgctatcg acgccgccaa ccgcgccctg cccgcctggc gcgcgctcac 840 cgccaaagaa cgcgccacca ttctgcgcaa ctggttcaat ttgatgatgg agcatcagga 900 cgatttagcg cgcctgatga ccctcgaaca gggtaaacca ctggccgaag cgaaaggcga 960 aatcagctac gccgcctcct ttattgagtg gtttgccgaa gaaggcaaac gcatttatgg 1020 cgacaccatt cctggtcatc aggccgataa acgcctgatt gttatcaagc agccgattgg 1080 cgtcaccgcg gctatcacgc cgtggaactt cccggcggcg atgattaccc gcaaagccgg 1140 tccggcgctg gcagcaggct gcaccatggt gctgaagccc gccagtcaga cgccgttctc 1200 tgcgctggcg ctggcggagc tggcgatccg cgcgggcgtt ccggctgggg tatttaacgt 1260 ggtcaccggt tcggcgggcg cggtcggtaa cgaactgacc agtaacccgc tggtgcgcaa 1320 actgtcgttt accggttcga ccgaaattgg ccgccagtta atggaacagt gcgcgaaaga 1380 catcaagaaa gtgtcgctgg agctgggcgg taacgcgccg tttatcgtct ttgacgatgc 1440 cgacctcgac aaagccgtgg aaggcgcgct ggcctcgaaa ttccgcaacg ccgggcaaac 1500 ctgcgtctgc gccaaccgcc tgtatgtgca ggacggcgtg tatgaccgtt ttgccgaaaa 1560 attgcagcag gcagtgagca aactgcacat cggcgacggg ctggataacg gcgtcaccat 1620 cgggccgctg atcgatgaaa aagcggtagc aaaagtggaa gagcatattg ccgatgcgct 1680 ggagaaaggc gcgcgcgtgg tttgcggcgg taaagcgcac gaacgcggcg gcaacttctt 1740 ccagccgacc attctggtgg acgttccggc caacgccaaa gtgtcgaaag aagagacgtt 1800 cggccccctc gccccgctgt tccgctttaa agatgaagct gatgtgattg cgcaagccaa 1860 tgacaccgag tttggccttg ccgcctattt ctacgcccgt gatttaagcc gcgtcttccg 1920 cgtgggcgaa gcgctggagt acggcatcgt cggcatcaat accggcatta tttccaatga 1980 agtggccccg ttcggcggca tcaaagcctc gggtctgggt cgtgaaggtt cgaagtatgg 2040 catcgaagat tacttagaaa tcaaatatat gtgcatcggt ctttaactgg agaatgcgaa 2100 tgaacagcaa taaagagtta atgcagcgcc gcagtcaggc gattccccgt ggcgttgggc 2160 aaattcaccc gattttcgct gaccgcgcgg aaaactgccg ggtgtgggac gttgaaggcc 2220 gtgagtatct tgatttcgcg ggcgggattg cggtgctcaa taccgggcac ctgcatccga 2280 aggtggtggc cgcggtggaa gcgcagttga aaaaactgtc gcacacctgc ttccaggtgc 2340 tggcttacga gccgtatctg gagctgtgcg agattatgaa tcagaaggtg ccgggcgatt 2400 tcgccaagaa aacgctgctg gttacgaccg gttccgaagc ggtggaaaac gcggtaaaaa 2460 tcgcccgcgc cgccaccaaa cgtagcggca ccatcgcttt tagcggcgcg tatcacgggc 2520 gcacgcatta cacgctggcg ctgaccggca aggtgaatcc gtactctgcg ggcatggggc 2580 tgatgccggg tcatgtttat cgcgcgcttt atccttgccc gctgcacggc ataagcgagg 2640 atgacgctat cgccagcatc caccggatct tcaaaaatga tgccgcgccg gaagatatcg 2700 ccgccatcgt gattgagccg gttcagggcg aaggcggttt ctacgcctcg tcgccagcct 2760 ttatgcagcg tttacgcgct ctgtgtgacg agcacgggat catgctgatt gccgatgaag 2820 tgcagagcgg cgcggggcgt accggcacgc tgtttgcgat ggagcagatg ggcgttgcgc 2880 cggatcttac cacctttgcg aaatcgatcg cgggcggctt cccgctggcg ggcgtcaccg 2940 ggcgcgcgga agtaatggat gccgtcgctc caggcggtct gggcggcacc tatgcgggta 3000 acccgattgc ctgcgtggct gcgctggaag tgttgaaggt gtttgagcag gaaaatctgc 3060 tgcaaaaagc caacgatctg gggcagaagt tgaaagacgg attgctggcg atagccgaaa 3120 aacacccgga gatcggcgac gtacgcgggc tgggggcgat gatcgccatt gagctgtttg 3180 aagacggcga tcacaacaag ccggacgcca aactcaccgc cgagatcgtg gctcgcgccc 3240 gcgataaagg cctgattctt ctctcctgcg gcccgtatta caacgtgctg cgcatccttg 3300 taccgctcac cattgaagac gctcagatcc gtcagggtct ggagatcatc agccagtgtt 3360 ttgatgaggc gaagcagtag cgccgctcct atgccggaga gcactgcgcg tcttgtccgg 3420 cctacgggga tccaggtcgg ataaggcgtt tacgccgcat ccgacaatct gtacgtgaac 3480 aggaagaaat ctatgttggc cgggtaaggc ggagccgctc tccggcaaaa agaatcaata 3540 acaattatac gcgtgacccg gcgcgggaaa tgtcggggcg ctctcccaag tgacacactt 3600 tcgagaggat tcaggatggg gcaatcatcg caaccacatg agttaggcgg cgggctgaag 3660 tcacgccacg tcaccatgtt gtctattgcc ggtgttatcg gcgcaagtct gtttgtcggt 3720 tccagcgtcg ccatcgccga agcgggcccg gcggtattac tggcctatct gttcgccggg 3780 ctactggtgg ttatgattat gcggatgttg gcggaaatgg cggttgccac gcccgatacc 3840 ggttcgtttt ccacctatgc cgataaagcc attggtcgct gggcgggcta taccatcggc 3900 tggttgtact ggtggttttg ggtactggtt atcccgctgg aagccaacat cgccgccatg 3960 atcctgcact catgggttcc aggcattccc atctggttat tttccctcgt cattaccctc 4020 gccttaactg gcagtaactt attaagcgtt aaaaactacg gcgaatttga gttctggctg 4080 gcgctgtgca aagtcatcgc tatcctggcc tttattttcc ttggtgcagt cgcaattagc 4140 ggtttttacc cgtatgccga agtgagcggg atctcaagat tgtgggatag cggcggcttt 4200 atgcccaacg gtttcggtgc ggtattaagc gcgatgttga tcaccatgtt ctcgtttatg 4260 ggcgcagaaa ttgtcaccat tgccgccgcg gaatccgaca cgccggaaaa acatattgtc 4320 cgcgccacca actcggttat ctggcgtatt tctatcttct atttatgttc tatttttgtc 4380 gtcgtggcat taattccgtg gaatatgccc ggactaaaag ccgtcggttc ttatcgctcg 4440 gtactggaat tgctcaatat tccccatgcg aaattaatca tggactgcgt gatattactt 4500 tccgtaacca gttgcctgaa ctcggcgctg tataccgcgt caaggatgct ctactcctta 4560 agtcgtcgcg gtgatgctcc cgcggtaatg ggtaaaatca accgcagtaa aaccccgtac 4620 gtggcggtgt tactctccac cggcgcggca ttcttaacgg tggtggtgaa ctattacgcg 4680 cctgcgaagg tatttaaatt tctgatcgac agctccggcg ctatcgccct gctggtttat 4740 ttagtcatcg ccgtttcaca gttgcggatg cgcaaaattc tgcgagcaga aggaagcgaa 4800 attcgcttgc gaatgtggct ttatccgtgg ctcacctggc tagtcatcgg ctttattacc 4860 tttgtgttgg tagtgatgct attccgtccg gcgcaacagt tagaagtgat ctccaccggc 4920 ttattagcga tagggattat ctgtaccgtg ccaattatgg ctcgctggaa aaagctggta 4980 ttgtggcaaa aaacacccgt tcataatacg cgctgatcat gatcaggagt cacaccatga 5040 ccattacgtc tctggatggc tatcgctggc tgaagaacga tattattcgc ggtaattttc 5100 aaccggatga aaaattacga atgagtttgc tgacatcgcg ttatgcactt ggcgttgggc 5160 cgttacggga agctctttcg caactggtgg cggaacggct ggtcacggtg gtgaatcaaa 5220 aagggtatcg ggtggcgtct atgtcagagc aggagctgct cgatattttc gacgcccgcg 5280 ccaatatgga agcgatgtta gtgagtctgg cgattgcccg cggtggcgat gagtgggagg 5340 cagacgttct cgcaaaagcg catctgctga gtaagctt 5378 // |
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