spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   M86544; SV 1; linear; mRNA; STD; MAM; 1229 BP.
XX
AC   M86544;
XX
DT   06-FEB-1992 (Rel. 30, Created)
DT   07-OCT-2008 (Rel. 97, Last updated, Version 5)
XX
DE   Cow prostaglandin F synthetase II (PGFSII) mRNA, complete cds.
XX
KW   aldo-keto reductase; prostaglandin D-2; prostaglandin F synthetase II;
KW   prostaglandin H-2.
XX
OS   Bos taurus (cattle)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
XX
RN   [1]
RP   1-1229
RX   DOI; 10.1016/S0006-291X(05)80323-7
RX   PUBMED; 1339268.
RA   Kuchinke W., Barski O., Watanabe K., Hayaishi O.;
RT   "A lung type prostaglandin F synthase is expressed in bovine liver: cDNA
RT   sequence and expression in E. coli";
RL   Biochem. Biophys. Res. Commun. 183(3):1238-1246(1992).
XX
DR   Ensembl-Gn; ENSBTAG00000001226; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000013756; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000022570; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000032443; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000035649; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000035982; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000037379; Bos_taurus.
DR   Ensembl-Gn; ENSBTAG00000039179; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000024086; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000031300; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000035476; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000045894; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000046856; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000050133; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000050480; Bos_taurus.
DR   Ensembl-Tr; ENSBTAT00000053133; Bos_taurus.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1229
FT                   /organism="Bos taurus"
FT                   /mol_type="mRNA"
FT                   /tissue_type="liver"
FT                   /db_xref="taxon:9913"
FT   CDS             16..987
FT                   /codon_start=1
FT                   /gene="PGFSII"
FT                   /product="prostaglandin F synthetase II"
FT                   /EC_number="1.1.1.2"
FT                   /db_xref="GOA:P52897"
FT                   /db_xref="InterPro:IPR001395"
FT                   /db_xref="InterPro:IPR018170"
FT                   /db_xref="InterPro:IPR020471"
FT                   /db_xref="UniProtKB/Swiss-Prot:P52897"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="AAA30730.1"
FT                   /translation="MDPKSQRVKFNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVG
FT                   FRHVDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQ
FT                   NLQLDYVDLYIIHSPVSLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSI
FT                   GVSNFNHKQLEKILNKPGLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQ
FT                   LLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENM
FT                   QVFDFELTPEDMKAIDGLNRNTRYYDFQQGIGHPEYPFSEEY"
FT   variation       45
FT                   /gene="PGFSII"
FT                   /note="the conserved leu is replaced by phe"
XX
SQ   Sequence 1229 BP; 365 A; 256 C; 290 G; 318 T; 0 other;
     gaggagcaac aaacaatgga tcccaaaagc cagagggtga agtttaatga tggccacttc        60
     attcctgtcc tgggatttgg aacctatgca cctgaggagg ttcctaagag tgaagccctg       120
     gaggccacca aatttgctat agaggttggg ttccgccatg tggacagtgc tcatttgtat       180
     caaaatgagg agcaggttgg ccaggccatt cgaagcaaga ttgcagatgg cactgtgaag       240
     agagaagaca tattctacac ttcaaagctt tggtgcaatt cccttcaacc agagttggtc       300
     cgaccagcct tggaaaagtc attgcaaaat cttcaactgg actatgtcga tctctatatt       360
     attcattctc cagtgtctct gaagccaggg aataaatttg ttccaaaaga tgaaagtgga       420
     aaactgatat ttgactcggt ggatctctgt cacacgtggg aggccctgga gaagtgtaag       480
     gacgcagggc tgaccaagtc cattggggtg tccaacttca accacaagca gctagagaag       540
     atcctgaaca agccggggct caagtacaag cccgtctgca accaggtgga atgtcaccct       600
     tacctcaacc agagcaaact gttagagttc tgcaagtcac atgatattgt cctagttgct       660
     tatgctgctc tgggagccca actattgtca gaatgggtga actcaaacaa ccccgttctc       720
     ttggaggacc cggttctttg tgccattgcc aaaaagcaca agcagacccc agctctggtt       780
     gcccttcgct accaggtaca acgtggagtt gtggttctgg ccaagagttt caacaagaag       840
     aggatcaaag agaatatgca ggtgtttgac tttgaactga ctccggaaga tatgaaagca       900
     atcgatggcc tcaatcgtaa tacaagatac tatgattttc aacagggtat tggtcaccct       960
     gagtacccat tttctgaaga atattaactg ggtgagctgt ccaccatggc ttctacctga      1020
     acgtctgctt ctagggctac gaagagcgtg tctatacttg gtggaggtgt ttaaaagaag      1080
     tgcctgaact tttgaaagat tgtttttctt taaaaattct ttatgaaata accaagattt      1140
     caaatatggg tactagtttt tcctaacaaa ataatttgaa aaataaaagg gaaaagatag      1200
     aaaataaaga taacctggtt aacccattt                                        1229
//
spacer
spacer