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EBI DbfetchID M85265; SV 1; linear; genomic DNA; STD; PRO; 2928 BP. XX AC M85265; XX DT 03-FEB-1992 (Rel. 30, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 9) XX DE Lactobacillus casei phosphoribosylformylglycinamide (purQ) gene 3' end, DE (purF) gene 5' end, (purL) gene, complete cds. XX KW amidophosphoribosyltransferase; KW phosphoribosylformylglycinamidine synthase I; KW phosphoribosylformylglycinamidine synthase II; purF gene; purL gene; KW purQ gene. XX OS Lactobacillus casei OC Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus. XX RN [1] RP 1-2928 RX DOI; 10.1016/0378-1119(92)90076-2 RX PUBMED; 1398079. RA Gu Z.M., Martindale D.W., Lee B.H.; RT "Isolation and complete sequence of the purL gene encoding FGAM synthase II RT in Lactobacillus casei"; RL Gene 119(1):123-126(1992). XX RN [2] RP 1-2928 RX DOI; 10.1074/jbc.270.29.17394 RX PUBMED; 7542237. RA Kim J.H.y.u.n., Wolle D., Haridas K., Parry R.J., Smith L., Zalkin H.; RT "A stable carbocyclic analog of 5-phosphoribosyl-1-pyrophosphate to probe RT the mechanism of catalysis and regulation of glutamine RT phosphoribosylpyrophosphate amidotransferase"; RL J. Biol. Chem. 270(29):17394-17399(1995). XX CC NCBI gi: 308865 XX FH Key Location/Qualifiers FH FT source 1..2928 FT /organism="Lactobacillus casei" FT /mol_type="genomic DNA" FT /db_xref="taxon:1582" FT CDS 3..167 FT /codon_start=1 FT /transl_table=11 FT /gene="purQ" FT /product="phosphoribosylformylglycinamidine synthase I" FT /note="NCBI gi: 149586" FT /db_xref="GOA:P35851" FT /db_xref="UniProtKB/Swiss-Prot:P35851" FT /protein_id="AAC36946.1" FT /translation="MHDIAGVTNETGNVLGMMPHPERAVEALLGGTDGLGVFQSLINQT FT EGADVRGAR" FT CDS 148..2370 FT /codon_start=1 FT /transl_table=11 FT /gene="purL" FT /product="phosphoribosylformylglycinamidine synthase II" FT /note="NCBI gi: 308866" FT /db_xref="GOA:P35852" FT /db_xref="InterPro:IPR000728" FT /db_xref="InterPro:IPR010074" FT /db_xref="InterPro:IPR010918" FT /db_xref="InterPro:IPR016188" FT /db_xref="UniProtKB/Swiss-Prot:P35852" FT /protein_id="AAC36947.1" FT /translation="MYVVHVEMSPEAIATQKPYLDLGLTEAEYDRFAELIGHQPNDTEI FT GLASGMWSEHCAYKYSKPVLRQFWTKNERVLMGPGEGAGVIDIGEGKAVVFKAESHNHP FT SAVEPYEGAATGVGGIIRDIFSIGAKPVAMLDSLAFGDIEQPHTQHLVDRIVAGIGGYG FT NAIGIPTVGGETNFDGSYTRNPLVNAMCVGIMDKDQIQKGKAAGVGNALIYVGAKTGRD FT GINGASFASGDFSDEEAADRSAVQVGDPFMEKLLMDACLEITGHHQEALVGIQDMGAAG FT LVSSSVEMAGKANSGMVLDLDLIPQREAEMTPFEIMLSESQERMLLCVRAGFEQEVLAV FT FADYDLDAAIVGHVIAGHQYQLYHHGKLVCDVPVSSLTDDAPIYHQQGKMPKRLAQPAA FT DFDPIITDPVQIWTDMMAMPTIADKSSLYKRYDAQVQTNTVVLPGSDAAVIRIRGTHRA FT LAMTTDSKDVTCILIAGGCGNECWLKRARNLVASGAEPLGITDCLNFGDPTKPEAFYEL FT AEAAKGIIAATKAFNAPVISGNVSLYNETNGEAIYPTPMIGMVGLIEDLSTITTAAFKQ FT ADDLIYLVGETHGDFNGSELQKLQTGEVTGKLFDFDLEAEKQHQHFVLKAIREHLITAA FT HDLSDGGLLVALAEMGFDAQLGAQINVTLPTAWGFSETQGRFLLTVSPENQAAFEALHG FT PAQLIGRVQAPPEFEVTTVNQHFSASLQQLQTAFEEALPCHMNQKA" FT CDS 2346..>2928 FT /codon_start=1 FT /transl_table=11 FT /gene="purF" FT /product="amidophosphoribosyltransferase" FT /note="NCBI gi: 551881" FT /db_xref="GOA:P35853" FT /db_xref="InterPro:IPR000583" FT /db_xref="InterPro:IPR005854" FT /db_xref="InterPro:IPR017932" FT /db_xref="UniProtKB/Swiss-Prot:P35853" FT /protein_id="AAC36948.1" FT /translation="MPHEPKGLNEECGVFGVWGNPNAASITHLGLHTLQHRGQEGAGIV FT GLTKDGMRRHYGLGLLSEVFTNTDQLTPLIGRAALGHVRYSTAGGRVLENIQPLLFRFS FT DEAIALAHNGNLTNAISLRRQLEDQGAIFQSTSDTEVLMHLIRRQVGQPWLTQLKTALN FT EVHGGFAFVLLTEHGLYAAVDPHGFRPMVVG" XX SQ Sequence 2928 BP; 696 A; 650 C; 847 G; 735 T; 0 other; gcatgcacga tattgccggt gtgaccaatg agactggtaa tgtgttaggc atgatgcccc 60 atccggaacg ggctgttgaa gcactgctgg gcggtacgga tggcttgggc gtattccaat 120 cgctgattaa ccaaacggaa ggagccgatg tacgtggtgc acgttgagat gagccccgag 180 gctattgcaa cccagaaacc ttatttagac cttgggctga cagaggctga atatgatcgt 240 tttgcagaac taatcggcca tcagccaaac gataccgaga tcgggttagc tagcggtatg 300 tggagcgaac actgcgctta caaatatagc aagccggtat tacgccaatt ttggaccaaa 360 aatgagcgcg tgttaatggg gccaggtgaa ggtgctggcg tgattgatat cggcgaaggc 420 aaagcagtgg tcttcaaagc cgaaagtcat aatcatccct cggcagttga accttatgaa 480 ggcgcagcaa caggtgtggg cggcataatc cgcgacattt tctcaattgg tgccaagccg 540 gttgcgatgt tggactcgct agcttttggc gacattgaac agccacatac ccaacatttg 600 gttgatcgga ttgtcgcggg gattggcggt tatggcaatg caattggcat tccgacagtt 660 ggcggcgaaa caaactttga cgggagctat acccgaaatc cgctggtcaa tgccatgtgc 720 gttggcatca tggacaaaga tcaaattcaa aaaggtaaag ctgctggtgt tggcaatgct 780 ttgatttatg tcggggccaa aacagggcgt gatggtatta acggtgcgag ctttgcttct 840 ggggattttt ctgacgaaga agcagccgat cgctcggcgg ttcaagttgg cgatcccttc 900 atggaaaagc tgttgatgga tgcttgtctc gaaattaccg ggcatcatca ggaggcgctt 960 gttggtattc aagatatggg tgcagctgga ttggtatcgt caagcgtgga gatggctggt 1020 aaggctaaca gcgggatggt gttagatctc gatctgattc cgcagcgtga agccgaaatg 1080 acgccgtttg aaattatgtt gtctgagtct caggaacgga tgctgctatg cgttcgggcc 1140 ggctttgagc aagaagtttt ggctgttttc gccgattatg atttggatgc ggcgattgtt 1200 ggtcatgtga ttgctggtca tcagtatcag ctttatcacc atggcaaatt ggtttgcgat 1260 gtgcctgtga gttcgttgac cgatgatgcg ccgatttatc atcaacaagg gaaaatgcca 1320 aaacgactgg cccaaccggc tgcggatttt gaccctatca tcactgatcc ggtgcaaata 1380 tggacggaca tgatggcgat gccgacgatt gctgacaagt catctttgta caagcgttac 1440 gatgcgcagg tgcaaactaa taccgtcgtc ttgccaggca gtgatgcagc cgtgattcgg 1500 attcgcggta ctcaccgagc actggcgatg accaccgata gtaaggacgt tacttgtatc 1560 ttgatcgcag gtgggtgcgg caatgagtgt tggctgaaac gtgcgcgcaa tttggttgcc 1620 agcggggcgg aaccgcttgg gatcaccgat tgtctcaatt ttggcgaccc aactaagcct 1680 gaggccttct acgaactggc tgaggcggcg aagggaatca ttgcggctac caaagccttt 1740 aacgccccag ttatttcagg aaatgtgtcg ctgtataacg aaacgaatgg tgaggcgatc 1800 tatccaaccc caatgattgg catggttggc ttgattgagg atttgagcac gatcaccacg 1860 gcggctttca agcaagcaga tgatctgatt tatctggtgg gggaaactca tggtgatttt 1920 aacggcagcg aactgcagaa gctgcaaaca ggagaagtca ctggcaagct gttcgatttt 1980 gatttagagg ctgaaaagca gcatcagcac tttgttttga aggccattcg cgagcatcta 2040 attactgcag cgcacgattt aagcgatggt gggttgttgg tcgccttggc agagatgggg 2100 tttgatgccc aacttggcgc ccagattaac gtcacattgc cgactgcttg gggattttcc 2160 gagacgcaag gccgcttctt gctcaccgtg tcccctgaaa atcaggcagc atttgaagca 2220 ttgcatggcc cggcccaatt gattggtcga gttcaggccc caccagaatt tgaagtcaca 2280 accgttaatc aacatttttc tgcatcgttg caacagctac agacagcatt cgaggaggcg 2340 ctcccatgcc acatgaacca aaaggcttaa atgaagaatg cggggttttc ggtgtttggg 2400 gtaatcctaa tgccgccagc atcacgcatc ttgggttaca cacactacag caccgcggtc 2460 aagaaggcgc cggtattgtt gggctgacca aagacgggat gcggcggcat tatgggttgg 2520 ggttactgag cgaagttttc acgaataccg atcaattgac gccattaatc ggacgcgccg 2580 ccttgggcca cgtgcgctac tcgacagcag ggggacgcgt gctggaaaac attcagccgt 2640 tgcttttccg gttttcggat gaagccattg ccttggcgca taatggcaat ctgaccaatg 2700 cgatcagttt gcggcggcag ttggaagatc aaggcgcaat ttttcagtcc acctccgata 2760 cggaagtttt gatgcattta atccgacggc aagttggcca gccttggctg acacagttga 2820 agaccgcttt aaatgaagtt catggtggtt ttgcgtttgt cttactgacg gaacatggtt 2880 tatatgccgc agttgatccg catggctttc ggccgatggt tgtcgggg 2928 // |
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