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EBI DbfetchID M83531; SV 1; linear; genomic DNA; STD; PRO; 1890 BP. XX AC M83531; XX DT 31-MAR-1992 (Rel. 31, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 8) XX DE H.volcanii 3-hydroxy-3-methylglutaryl coenzyme A reductase (hmg) gene, DE complete cds. XX KW 3-hydroxy-3-methylglutaryl coenzyme A reductase; mevinolin resistance. XX OS Haloferax volcanii OC Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; OC Haloferax. XX RN [1] RP 1-1890 RX PUBMED; 1556098. RA Lam W.L., Doolittle W.F.; RT "Mevinolin-resistant mutations identify a promoter and the gene for a RT eukaryote-like 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the RT archaebacterium Haloferax volcanii"; RL J. Biol. Chem. 267(9):5829-5834(1992). XX FH Key Location/Qualifiers FH FT source 1..1890 FT /organism="Haloferax volcanii" FT /map="17 genome %" FT /strain="WFD11" FT /mol_type="genomic DNA" FT /db_xref="taxon:2246" FT variation 513 FT /gene="hmg" FT /note="t to g in mevinolin resistance" FT gene 542..1753 FT /gene="hmg" FT CDS 542..1753 FT /codon_start=1 FT /transl_table=11 FT /gene="hmg" FT /product="3-hydroxy-3-methylglutaryl coenzyme A reductase" FT /EC_number="1.1.1.34" FT /db_xref="GOA:Q59468" FT /db_xref="HSSP:1HW8" FT /db_xref="InterPro:IPR004554" FT /db_xref="UniProtKB/Swiss-Prot:Q59468" FT /protein_id="AAA73174.1" FT /translation="MTDAASLADRVREGDLRLHELEAHADADTAAEARRLLVESQSGAS FT LDAVGNYGFPAEAAESAIENMVGSIQVPMGVAGPVSVDGGSVAGEKYLPLATTEGALLA FT SVNRGCSVINSAGGATARVLKSGMTRAPVFRVADVAEAEALVSWTRDNFAALKEAAEET FT TNHGELLDVTPYVVGNSVYLRFRYDTKDAMGMNMATIATEAVCGVVEAETAASLVALSG FT NLCSDKKPAAINAVEGRGRSVTADVRIPREVVEERLHTTPERGRELNTRKNLVGSAKAA FT SLGFNAHVANVVAAMFLATGQDEAQVVEGANAITTAEVQDGDLYVSVSIASLEVGTVGG FT GTKLPTQSEGLDILGVSGGGDPAGSNADALAECIAVGSLAGELSLLSALASRHLSSAHA FT ELGR" XX SQ Sequence 1890 BP; 277 A; 700 C; 638 G; 275 T; 0 other; ctcgagtcgt cccacgtgct ctcgtcgtag ccgtagccga gcacccagcc ggcctcgtcg 60 ccggtctcgt cgtcggattc gacctcggcg gcgcgctcgc ggagcagttc gaccgcctcc 120 gccggggagc cggcggcgga gaggtcggcg tggacgagcg agcggccgac catcgggagg 180 tgcgtgtggg cgtcgatgaa gccggggagg acgacgcggc cgccgcagtc gacgacccgc 240 gtctcgacgc cggcgagcag tcccacgtcg aacgcgcggc cgacgcggac gacctcgccg 300 tcgcggacgg acggcttcgt gcgtctcgtc gggcgacccg agggtgtgta cctccgcgtt 360 cgtcagtacg aggtccgctg ccgcggtcat acgttcgacc ccgacgcggg agggcaaaac 420 ggttcgggag gcggcggggt ggccgagcgg cggtcggtcg tcgcgggtga cgccggccgg 480 gtcggtggcg gccgttggaa gaaccggaac gctttagggc cggcgcggga aacgtcggag 540 catgacagac gccgcgtccc tcgcagaccg cgttcgggag ggcgacctcc gcctccacga 600 actcgaagcg cacgccgacg ccgacaccgc cgccgaggcg cgccgactgc tcgtcgaatc 660 gcagtccggc gcgtcgctcg acgcggtcgg gaactacggc ttccccgcgg aggccgccga 720 gtccgccatc gagaacatgg tcggctcgat ccaggtgccg atgggcgtcg ccggccccgt 780 cagcgtcgac ggcggctccg tcgccggcga gaagtacctc cccctcgcga ccaccgaggg 840 cgcgctcctc gcgtcggtca accgcggttg ctcggtcatc aacagcgccg gcggcgcgac 900 cgcccgcgtc ctcaagtccg ggatgacccg cgcgccggtg ttccgcgtcg ccgacgttgc 960 cgaggccgag gcgctcgtct cgtggacccg cgacaacttc gcggcgctga aggaggccgc 1020 ggaggagacg acgaaccacg gcgaactcct cgacgtgacg ccgtacgtcg tcggcaactc 1080 ggtgtacctg cgattccgct acgacaccaa ggacgcgatg gggatgaaca tggccaccat 1140 cgccaccgag gccgtctgcg gcgtcgtcga agccgagacg gccgcctcgc tcgtcgccct 1200 ctcgggcaac ctctgttccg acaagaagcc cgccgccatc aacgccgtcg aggggcgcgg 1260 ccggagcgtc accgccgacg ttcgaatccc gcgcgaggtc gtcgaagaac gcctgcacac 1320 cacgcccgaa cgcggtcgcg aactcaacac acgcaagaac ctggtcggct ccgcgaaggc 1380 cgcgagcctc gggttcaacg cccacgtcgc caacgtcgtc gccgcgatgt tcctcgccac 1440 cgggcaggac gaggcgcagg tcgtcgaggg cgcgaacgcc atcacgaccg ccgaggtgca 1500 ggacggcgac ctctacgtct cggtctccat cgcctccctc gaagtcggca ccgtcggcgg 1560 cggcacgaaa ctcccgacgc agtccgaggg cctcgatatc ctcggcgtca gcggcggcgg 1620 cgaccccgcc ggctccaacg ccgacgccct cgccgaatgc atcgccgtcg gttccctcgc 1680 gggcgaactc tcccttctct ccgcgctcgc ctcgcggcac ctctccagcg cccacgccga 1740 actcggtcgg taactcgcgg gttcattttc accgacagca gggacggctg gactgccttt 1800 tcttcgccgt tgttccggtc tgttcctccg acttcgcacc tcgtcacgtt tcactttcac 1860 tttcactccg cacctgtggg tcgcgtttat 1890 // |
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