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EBI DbfetchID M80675; SV 1; linear; genomic DNA; STD; VRL; 3536 BP. XX AC M80675; M61767; XX DT 30-OCT-1991 (Rel. 30, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 3) XX DE AKT8 provirus v-akt oncogene, complete cds. XX KW protein kinase C-related; serine/threonine protein kinase; SH2 domain; KW transforming capacity. XX OS AKT8 retrovirus OC Viruses; Retro-transcribing viruses; Retroviridae. XX RN [1] RP 1-3536 RX DOI; 10.1126/science.1833819 RX PUBMED; 1833819. RA Bellacosa A., Testa J.R., Staal S.P., Tsichlis P.N.; RT "A retroviral oncogene, akt, encoding a serine-threonine kinase containing RT an SH2-like region"; RL Science 254(5029):274-277(1991). XX DR RFAM; RF00374; Gammaretro_CES. XX FH Key Location/Qualifiers FH FT source 1..3536 FT /organism="AKT8 retrovirus" FT /mol_type="genomic DNA" FT /cell_line="95785" FT /proviral FT /db_xref="taxon:12438" FT CDS 324..2615 FT /codon_start=1 FT /gene="v-akt" FT /product="gag:akt fusion protein" FT /db_xref="GOA:P31748" FT /db_xref="HSSP:1H10" FT /db_xref="InterPro:IPR015744" FT /db_xref="UniProtKB/Swiss-Prot:P31748" FT /protein_id="AAA42545.1" FT /translation="MGQTVTTPLSLTLEHWGDVQRIASNQSVDVKKRRWVTFCSAEWPT FT FGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPK FT LSLSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLTEDPPP FT YGEQGPSSSDGDGDREEATSTPEIPAPSPMVSRLRGKRDPPAAVSTTSRAFPLRLGGNG FT QLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHAREETLIIIPGLPLSLGAT FT DTMNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSV FT AQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEE FT TMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRY FT YAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGE FT LFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF FT GLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ FT DHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANI FT VWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFP FT QFSYSASGTA" XX SQ Sequence 3536 BP; 779 A; 1027 C; 928 G; 802 T; 0 other; agatctgtat ctggcggttc cgtggaagaa ctgacgagtt cgtattcccg accgcagccc 60 tgggagacgt ctcagaggca tcaggggccc gctgggtggc ccaatcagta agtccgagtc 120 ctgaccgatt cggactattt ggagcccctc ctttgtcgga ggggtacgtg gttcttttag 180 gagacgagag gtccaagccc tcgccgcctc catctaaatt tttgctttcg gtttttcgcc 240 gaaaccgcgc cgcgcgtctt gtctgtctca gtgttgtttt gtcatttgtc tgttcgttat 300 tgttttggac cgtttctaaa aatatgggac agaccgtaac cacccctctg agtctgaccc 360 tagaacactg gggagacgtc cagcgcatcg cgtccaacca gtccgtggac gtcaagaaga 420 gacgctgggt caccttctgc tctgccgagt ggccaacttt cggtgtaggg tggccgcaag 480 atggtacttt taatttggac attattttac aggttaaatc taaggtgttc tctcccggtc 540 cccacggaca cccggatcag gtcccataca ttgtcacctg ggaggctatt gcctatgaac 600 cccctccgtg ggtcaaacct tttgtctctc ccaaactctc cctctctcca accgctccca 660 tcctcccatc cggtccttcg acccaacctc cgccccgatc tgccctttac cctgctctta 720 ccccctctat aaaacccaga ccttctaaac ctcaggttct ctccgataat ggcggacctc 780 tcattgacct tctcacagaa gaccctccgc cgtacggaga acagggaccg tcctcctctg 840 acggagatgg cgacagagaa gaggccacct ccactcctga gattcctgcc ccctctccca 900 tggtgtctcg cttgcggggc aaaagagacc cccccgcggc agtttccacc acctctcggg 960 ctttcccact ccgtttgggg ggtaatggtc agttgcagta ctggccgttt tcctcctcgg 1020 atctatataa ctggaaaaat aataaccctt ccttctctga agatccaggt aaattgactg 1080 ccttaatcga gtctgtcctc accacccacg cgcgagaaga gactctgatc atcatccctg 1140 ggttacccct gtctctgggg gccacggata ccatgaacga cgtagccatt gtgaaggagg 1200 gctggctgca caaacgaggg gaatatatta aaacctggcg gccacgctac ttcctcctca 1260 agaacgatgg cacctttatt ggctacaagg aacggcctca ggatgtggat cagcgagagt 1320 ccccactcaa caacttctca gtggcacaat gccagctgat gaagacagag cggccaaggc 1380 ccaacacctt tatcatccgc tgcctgcagt ggaccacagt cattgagcgc accttccatg 1440 tagaaacgcc tgaggagcgg gaagaatggg ccaccgccat tcagactgtg gccgatggac 1500 tcaagaggca ggaagaagag acgatggact tccgatcagg ctcacccagt gacaactcag 1560 gggctgaaga gatggaggtg tccctggcca agcccaagca ccgtgtgacc atgaacgagt 1620 ttgagtacct gaaactactg ggcaagggca cctttgggaa agtgattctg gtaaaagaga 1680 aggccacagg ccgctactat gccatgaaga tcctcaagaa ggaggtcatc gtcgccaagg 1740 atgaggttgc ccacacgctt actgaaaacc gtgtcctgca gaactctagg catcccttcc 1800 ttacggccct caagtactca ttccagaccc acgaccgcct ctgctttgtc atggagtatg 1860 ccaacggggg cgagctcttc ttccacctgt ctcgagagcg cgtgttctcc gaggaccggg 1920 cccgcttcta tggtgcggag attgtgtctg ccctggacta cttgcactcc gagaagaacg 1980 tggtgtaccg ggacctgaag ctagagaacc tcatgctgga caaggacggg cacatcaaga 2040 taacggactt cgggctgtgc aaggagggga tcaaggatgg tgccactatg aagacattct 2100 gcggaacgcc ggagtacctg gcccctgagg tgctggaaga caacgactac ggccgtgcag 2160 tggactggtg ggggctgggc gtggtcatgt atgagatgat gtgtggccgc ctgcccttct 2220 acaaccagga ccacgagaag ctgttcgagc tgatcctcat ggaggagatc cgcttcccgc 2280 gcacactcgg ccctgaggcc aagtccctgc tctccgggct gctcaagaag gaccctacac 2340 agaggctcgg tgggggctct gaggatgcca aggagatcat gcagcaccgg ttctttgcca 2400 acatcgtgtg gcaggatgtg tatgagaaga agctgagccc acctttcaag ccccaggtca 2460 cctctgagac tgacaccagg tatttcgatg aggagttcac agctcagatg atcaccatca 2520 cgccgcctga tcaagatgac agcatggagt gtgtggacag tgagcggagg ccgcacttcc 2580 cccagttctc ctactcagcc agtggcacag cctgaggcct ggggcagcgg ctggcagctc 2640 cacgctcctc tgcattgccg agtccagaag ccccgcatgg atcatctgaa cctgatgttt 2700 tgtttctcgg atgcgctggg gaggaacctt gccagcctcc aggaccaggg gaggatgttt 2760 ctactgtggg cagcagctac ctcccagcca ggtcaggagg aaaactatcc tggggttttt 2820 cttaatttat ttcatccagt ttgagaccac acatgtggcc tcagtgccca gaacaattag 2880 attcatgtag aaaactatta aggactgacg cgaccatgtg caatgtgggc tcatgggtct 2940 gggtgggtcc cgtcactgcc cccattggcc tgtccaccct ggccgccacc tgtctctagg 3000 gtccagggcc aaagtccagc aagaaggcac caaaagcacc tccctgtggt atgctaactg 3060 gccctctccc tctgggcggg gagaggtcac agctgcttca gccctagggc tggatgggat 3120 ggccagggct caagtgaggt tgacagagga acaagaatcc agtttgttgc tgtgtcccat 3180 gctgttcaga gacatttagg ggattttaat cttggtgaca ggagagcccc tgccctcccg 3240 ctcctgcgtg gtggctctta gcgggtaccc tgggagcgcc tgcctcacgt gagcccttct 3300 cctagcactt gtccttttag atgctttccc tctcccgctg tccgtcaccc tggcctgtcc 3360 cctcccggcc agacgctggc cattgctgca ccatgtcgtt ttttacaaca ttcagcttca 3420 gcatttttac tattataata agaaactgtc cctccaaatt caataaaaat tgcttttcaa 3480 aaaaaaaaaa aaaaaaaaaa ggggcaagaa catttgactt ctatgtttgc cccggg 3536 // |
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