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EBI DbfetchID M72474; SV 1; linear; genomic DNA; STD; VRL; 4487 BP. XX AC M72474; XX DT 03-JUL-1991 (Rel. 28, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 11) XX DE Vaccinia virus gene ORF2, ORF3, ORF4, ORF5, ORF6, and ORF7 complete cds; DE ORF1, 5' end; ORF8, 3' end. XX KW 3-beta-hydroxysteroid dehydrogenase; actin-binding protein; KW Cu-Zn-superoxide dismutase; profilin. XX OS Vaccinia virus OC Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; OC Orthopoxvirus. XX RN [1] RP 1-4487 RX PUBMED; 1870190. RA Blasco R., Cole N.B., Moss B.; RT "Sequence analysis, expression, and deletion of a vaccinia virus gene RT encoding a homolog of profilin, a eukaryotic actin-binding protein"; RL J. Virol. 65(9):4598-4608(1991). XX FH Key Location/Qualifiers FH FT source 1..4487 FT /organism="Vaccinia virus" FT /strain="WR" FT /mol_type="genomic DNA" FT /db_xref="taxon:10245" FT CDS complement(<1..308) FT /codon_start=1 FT /note="ORF1; putative" FT /db_xref="InterPro:IPR003184" FT /db_xref="PDB:2VGA" FT /db_xref="UniProtKB/Swiss-Prot:P24766" FT /protein_id="AAA48307.1" FT /translation="MYSLVFVILMCIPFSFQTVYDDKSVCDSDNKEYMGIEVYVEATLD FT EPLRQTTCESKIHKYGASVSNGGLNISVDLLNCFLNFHTVGVYTNRDTVYAKFASLDP" FT CDS 472..873 FT /codon_start=1 FT /product="profilin" FT /note="ORF2:vaccinia virus profilin homolog; putative" FT /db_xref="GOA:Q76ZN5" FT /db_xref="InterPro:IPR002097" FT /db_xref="UniProtKB/Swiss-Prot:Q76ZN5" FT /protein_id="AAA48308.1" FT /translation="MAEWHKIIEDISKNNKFEDAAIVDYKTTKNVLAAIPNRTFAKINP FT GEIIPLITNRNILKPLIGQKYCIVYTNSLMDENTYAMELLTGYAPVSPIVIARTHTALI FT FLMGKPTTSRRDVYRTCRDHATRVRATGN" FT CDS 911..1495 FT /codon_start=1 FT /note="ORF3" FT /db_xref="InterPro:IPR009487" FT /db_xref="UniProtKB/Swiss-Prot:P26671" FT /protein_id="AAA48309.1" FT /translation="MMMMKWIISILTMSIMPVLAYSSSIFRFHSEDVELCYGHLYFDRI FT YNVVNIKYNPHIPYRYNFINRTLTVDELDDNVFFTHGYFLKHKYGSLNPSLIVSLSGNL FT KYNDIQCSVNVSCLIKNLATSTSTILTSKHKTYSLHRSTCITIIGYDSIIWYKDINDKY FT NGIYDFTAICMLIASTLIVTIYVFKKIKMNS" FT CDS 1503..1739 FT /codon_start=1 FT /note="ORF4" FT /db_xref="UniProtKB/TrEMBL:Q89663" FT /protein_id="AAA48310.1" FT /translation="MLLEMDKIKITVDSKIGNVVTISYNLEKITIDVTPKKKKEKDVLL FT AQSVAVEEAKDVKVEEKNIIDIEDDDDMDVESA" FT CDS complement(1837..2877) FT /codon_start=1 FT /product="3-beta-hydroxysteroid FT dehydrogenase/delta-5-4-isomerase" FT /note="ORF5:3-beta-hydroxysteroid dehydrogenase homolog; FT putative" FT /db_xref="GOA:P26670" FT /db_xref="InterPro:IPR002225" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:P26670" FT /protein_id="AAA48311.1" FT /translation="MAVYAVTGGAGFLGRYIVKLLISADDVQEIRVIDIVEDPQPITSK FT VKVINYIQCDINDFDKVREALDGVNLIIHTAALVDVFGKYTDNEIMKVNYYGTQTILAA FT CVDLGIKYLIYTSSMEAIGPNKHGDPFIGHEHTLYDISPGHVYAKSKRMAEQLVMKANN FT SVIMNGAKLYTCCLRPTGIYGEGDKLTKVFYEQCKQHGNIMYRTVDDDAVHSRVYVGNV FT AWMHVLAAKYIQYPGSEIKGNAYFCYDYSPSCSYDMFNLLLMKPLGIEQGSRIPRWMLK FT MYACKNDMKRILFRKPSLLNNYTLKISNTTFEVRTNNAELDFNYSPIFNVDVAFERTRK FT WLEESE" FT CDS 2924..3301 FT /codon_start=1 FT /product="Cu/Zn-superoxide dismutase" FT /note="ORF6:Cu-Zn superoxide dismutase homolog; putative" FT /db_xref="GOA:P26669" FT /db_xref="InterPro:IPR001424" FT /db_xref="UniProtKB/Swiss-Prot:P26669" FT /protein_id="AAA48312.1" FT /translation="MAVCIIDHDNIRGVIYFEPVHGKDKVLGSVIGLKSGTYSLIIHRY FT GDISQGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGV FT IGISYINEKIIHFLTINENGV" FT CDS 3291..4013 FT /codon_start=1 FT /note="ORF7" FT /db_xref="InterPro:IPR009352" FT /db_xref="UniProtKB/Swiss-Prot:P26672" FT /protein_id="AAA48313.1" FT /translation="MAFDISVNASKTINALVYFSTQQNKLVIRNEVNDTHYTVEFDRDK FT VVDTFISYNRHNDTIEIRGVLPEETNIGCAVNTPVSMTYLYNKYSFKLILAEYIRHRNT FT ISGNIYSALMTLDDLAIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVA FT LSSLVSKHWELTNKKYRCMALAEHISDSIPISELSRLRYNLCKYLRGHTESIEDKFDYF FT EDDDSSTCSAVTDRETDV" FT CDS complement(4061..>4487) FT /codon_start=2 FT /note="ORF8" FT /db_xref="InterPro:IPR009402" FT /db_xref="UniProtKB/Swiss-Prot:P26673" FT /protein_id="AAA48314.1" FT /translation="DPDNKMSYSSVMILGEFDIINISDNEAAFEFINSLLKSLLLLNTR FT QLKLLEYSISNDLLYAHINALEYIIKNTFNVPERQLILRGQYLTPIFSDLLKYAGLTIK FT SNILMWNKQFIKPVSDLYTSMRLLHCVTESYKVIGMG" XX SQ Sequence 4487 BP; 1473 A; 729 C; 780 G; 1505 T; 0 other; ggatccaaac tagcaaactt cgcgtatacg gtatcgcgat tagtgtatac accaactgta 60 tgaaaattaa gaaaacagtt taatagatca acagaaatat ttaatcctcc gtttgataca 120 gatgcaccat atttatggat tttggattca cacgttgttt gtctgagggg ttcgtctagc 180 gttgcttcta cataaacttc tattcccata tattctttat tgtcagaatc gcataccgat 240 ttatcatcat acactgtttg aaaactaaat ggtatacaca tcaaaataac aaatactaac 300 gagtacattc tgcaatattg ttatcgtaat tggaaaaata gtgttcgagt gagttggatt 360 atgtgagtat tggattgtat attttatttt atattttgta ataagaataa aatgctaatg 420 tcaagtttat tccaatagat gtcttattaa aaacatatat aataaataac aatggctgaa 480 tggcataaaa ttatcgagga tatctcaaaa aataataagt tcgaggatgc cgccatcgtt 540 gattacaaga ctacaaagaa tgttctagct gctattccta acagaacatt tgccaagatt 600 aatccgggtg aaattattcc tctcatcact aatcgtaata ttctaaaacc tcttattggt 660 cagaaatatt gtattgtata tactaactct ctaatggatg agaacacgta tgctatggag 720 ttgcttactg ggtacgcccc tgtatctccg atcgttatag cgagaactca taccgcactt 780 atatttttga tgggtaagcc aacaacatcc agacgtgacg tgtatagaac gtgtagagat 840 cacgctaccc gtgtacgcgc aactggtaat taaaataaaa agtaatattc atatgtagtg 900 tcaattttaa atgatgatga tgaaatggat aatatccata ttgacgatgt caataatgcc 960 ggtattggca tacagctcat cgatttttag atttcattca gaggatgtgg aattatgtta 1020 tgggcatttg tattttgata ggatctataa tgtagtaaat ataaaatata atccgcatat 1080 tccatataga tataatttta ttaatcgcac gttaaccgta gatgaactag acgataatgt 1140 cttttttaca catggttatt ttttaaaaca caaatatggt tcacttaatc ctagtttgat 1200 tgtctcatta tcaggaaact taaaatataa tgatatacaa tgctcagtaa atgtatcgtg 1260 tctcattaaa aatttggcaa cgagtacatc tactatatta acatctaaac ataagactta 1320 ttctctacat cggtccacgt gtattactat aataggatac gattctatta tatggtataa 1380 agatataaat gacaagtata atggcatcta tgattttact gcaatatgta tgctaatagc 1440 gtctacattg atagtgacca tatacgtgtt taaaaaaata aaaatgaact cttaattatg 1500 ctatgctatt agaaatggat aaaatcaaaa ttacggttga ttcaaaaatt ggtaatgttg 1560 ttaccatatc gtataacttg gaaaagataa ctattgatgt cacacctaaa aagaaaaaag 1620 aaaaggatgt attattagcg caatcagttg ctgtcgaaga ggcaaaagat gtcaaggtag 1680 aagaaaaaaa tattatcgat attgaagatg acgatgatat ggatgtagaa agcgcataat 1740 acgatctata aaaataagta tataaatact ttttatttac tgtactctta ctgtgtagtg 1800 gtgataccct actcgattat ttttttaaaa aaatacttat tctgattctt ctagccattt 1860 ccgtgttcgt tcgaatgcca catcgacgtt aaagataggg gagtagttga aatctagttc 1920 tgcattgttg gtacgcacct caaatgtagt gttggatatc ttcaacgtat agttgttgag 1980 tagtgatggt tttctaaata gaattctctt catatcattc ttgcacgcgt acatttttag 2040 catccatctt ggaattctag atccttgttc tattcccaat ggtttcatca atagaagatt 2100 aaacatatcg tacgaacacg atggagagta atcgtagcaa aagtaagcat ttcctttaat 2160 ctcagatccc ggatactgga tatattttgc agccaacacg tgcatccatg caacatttcc 2220 tacatatacc cggctatgca ccgcgtcatc atcgactgta cgatacataa tgttaccgtg 2280 ttgcttacat tgctcgtaaa agactttcgt caatttgtct ccttctccgt aaattccagt 2340 gggtcttagg caacaagtat acaattttgc tccattcatg attacggaat tattggcttt 2400 cataaccagt tgctcggcca tacgtttact ttttgcgtat acatgtcctg gtgatatatc 2460 ataaagggta tgctcatggc cgatgaatgg atcaccgtgt ttatttggtc ctattgcttc 2520 catgctacta gtatagatca aatacttgat tcctaggtcc acacaagctg ccaatatagt 2580 ctgtgttcca taatagttta ctttcatgat ttcattatcg gtgtattttc caaatacatc 2640 cactagagca gccgtatgaa taatcagatt taccccatct agcgcttctc tcaccttatc 2700 aaagtcgttt atatcacatt gtatatagtt tataacctta actttcgagg ttattggttg 2760 tggatcttct acaatatcta tgactctgat ttcttgaaca tcatctgcac taattaacag 2820 ttttactata tacctgccta gaaatccggc accaccagta accgcgtaca cggccattgc 2880 tgccactcat aatatcagac tacttattct attttactaa ataatggctg tttgtataat 2940 agaccacgat aatatcagag gagttattta ctttgaacca gtccatggaa aagataaagt 3000 tttaggatca gttattggat taaaatccgg aacgtatagt ttgataattc atcgttacgg 3060 agatattagt caaggatgtg attccatagg cagtccagaa atatttatcg gtaacatctt 3120 tgtaaacaga tatggtgtag catatgttta tttagataca gatgtaaata tatctacaat 3180 tattggaaag gcgttatcta tttcaaaaaa tgatcagaga ttagcgtgtg gagttattgg 3240 tatttcttac ataaatgaaa agataataca ttttcttaca attaacgaga atggcgtttg 3300 atatatcagt taatgcgtct aaaacaataa atgcattagt ttacttttct actcagcaaa 3360 ataaattagt catacgtaat gaagttaatg atacacacta cactgtcgaa tttgataggg 3420 acaaagtagt tgacacgttt atttcatata atagacataa tgacaccata gagataagag 3480 gggtgcttcc agaggaaact aatattggtt gcgcggttaa tacgccggtt agtatgactt 3540 acttgtataa taagtatagt tttaaactga ttttagcaga atatataaga cacagaaata 3600 ctatatccgg caatatttat tcggcattga tgacactaga tgatttggct attaaacagt 3660 atggagacat tgatctatta tttaatgaga aacttaaagt agactccgat tcgggactat 3720 ttgactttgt caactttgta aaggatatga tatgttgtga ttctagaata gtagtagctc 3780 tatctagtct agtatctaaa cattgggaat tgacaaataa aaagtatagg tgtatggcat 3840 tagccgaaca tatatctgat agtattccaa tatctgagct atctagacta cgatacaatc 3900 tatgtaagta tctacgcgga cacactgaga gcatagagga taaatttgat tattttgaag 3960 acgatgattc gtctacatgt tctgccgtaa ccgacaggga aacggatgta taattttttt 4020 tatagcgtga aggatatgat aaaaaatata attgttgtat ttatcccatt ccaatcacct 4080 tatatgattc tgtaacacaa tgaaggagtc tcatagatgt atagaggtca gatactggtt 4140 tgataaactg tttattccac atgagtatgt ttgactttat ggttagaccc gcatacttta 4200 acaaatcact gaaaattgga gttaggtatt gacctctcag aatcagttgc cgttctggaa 4260 cattaaatgt attttttatg atatactcca acgcatttat gtgggcatac aacaagtcat 4320 tactaatgga gtattccaag agttttagtt gtctagtatt taacaagaga agagatttca 4380 acagactgtt tatgaactcg aatgccgcct cattgtcgct tatattgatg atgtcgaatt 4440 ctcccaatat catcaccgat gagtagctca tcttgttatc gggatcc 4487 // |
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