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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   M13787; SV 1; linear; mRNA; STD; MUS; 601 BP.
XX
AC   M13787;
XX
DT   09-MAR-1987 (Rel. 11, Created)
DT   17-APR-2005 (Rel. 83, Last updated, Version 7)
XX
DE   Mouse Ig unrearranged transcribed H-chain V-region VH558 mRNA, clone A1/A4.
XX
KW   C-region; germline; immunoglobulin heavy chain; V-region.
XX
OS   Mus musculus (house mouse)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea;
OC   Muridae; Murinae; Mus.
XX
RN   [1]
RP   1-601
RX   DOI; 10.1016/0092-8674(85)90141-2
RX   PUBMED; 2578321.
RA   Yancopoulos G.D., Alt F.W.;
RT   "Developmentally controlled and tissue-specific expression of unrearranged
RT   VH gene segments";
RL   Cell 40(2):271-281(1985).
XX
DR   IMGT/LIGM; M13787.
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CC   The sequence below is annotated as a germline variable gene
CC   segment.
CC   This germline transcript has all of the characteristics of a mature
CC   mRNA: normally spliced, polyadenylated, and transported to the
CC   cytoplasm.  Preliminary experimental data indicate this VH
CC   transcript can be translated into protein [1].  A potential stop
CC   codon can be found at positions 398 to 400.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..601
FT                   /organism="Mus musculus"
FT                   /sub_species="domesticus"
FT                   /strain="BALB/c"
FT                   /mol_type="mRNA"
FT                   /cell_line="V to DJ rearranging pre-B cell"
FT                   /db_xref="taxon:10090"
FT   mRNA            <1..601
FT                   /note="VH558 mRNA"
FT   sig_peptide     26..82
FT   CDS             26..>376
FT                   /codon_start=1
FT                   /product="immunoglobulin heavy chain"
FT                   /note="precursor"
FT                   /db_xref="GOA:P06327"
FT                   /db_xref="InterPro:IPR003596"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR013106"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="UniProtKB/Swiss-Prot:P06327"
FT                   /protein_id="AAA38499.1"
FT                   /translation="MGWRWIFLFLLSGTAGVHCQVQLQQSGPELVKPGALVKISCKASG
FT                   YTFTSYDINWVKQRPGQGLEWIGWIYPGDGSTKYNEKFKGKATLTADKSSSTAYMQLSS
FT                   LTSENSAVYFCAR"
FT   mat_peptide     83..>376
FT                   /product="immunoglobulin heavy chain"
FT                   /note="VH558 region"
FT   misc_signal     377..415
FT                   /note="recombination recognition sequence; putative"
FT   iDNA            377..>601
FT                   /note="V-D intervening DNA (5' end +/- 1 bp)"
XX
SQ   Sequence 601 BP; 161 A; 128 C; 145 G; 167 T; 0 other;
     tgtggagagg acactgactc taaccatggg atggagatgg atctttcttt tcctcctgtc        60
     aggaactgca ggtgtccatt gccaggttca gctgcagcag tctggacctg agctggtgaa       120
     gcctggggct ttagtgaaga tatcctgcaa ggcttctggt tacaccttca caagctacga       180
     tataaactgg gtgaagcaga ggcctggaca gggacttgag tggattggat ggatttatcc       240
     tggagatggt agtactaagt acaatgagaa attcaagggc aaggccacac tgactgcaga       300
     caaatcctcc agcacagcct acatgcagct cagcagcctg acttctgaga actctgcagt       360
     ctatttctgt gcaagacaca gtgttgtaac cacatcctga gtgtgtcaga aaccctggag       420
     gagcaggaag ctgcactggg attgagatga cagaaatatt aatccttaga cttgctctga       480
     atttgtaatt ttgaatgtcc atttattacc tcctcctcag agtcctatag tgcctttttc       540
     agctttgtat atgtccatct gagtaaaatg atgatttttg aataaaccta aaattcttca       600
     c                                                                       601
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