 |
|
EBI DbfetchID L29063; SV 1; linear; genomic DNA; STD; FUN; 6072 BP. XX AC L29063; XX DT 24-FEB-1994 (Rel. 38, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Candida albicans fatty acid synthase alpha subunit (FAS2) gene, complete DE cds. XX KW FAS2 gene; fatty acid synthase alpha-subunit. XX OS Candida albicans OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; mitosporic Saccharomycetales; Candida. XX RN [1] RP 1-6072 RA Southard S.B., Cihlar R.L.; RT "Isolation and characterization of the Candida albicans FA52 gene"; RL Unpublished. XX FH Key Location/Qualifiers FH FT source 1..6072 FT /organism="Candida albicans" FT /strain="4918" FT /mol_type="genomic DNA" FT /tissue_lib="lambda fix II" FT /db_xref="taxon:5476" FT TATA_signal 121..124 FT /gene="FAS2" FT mRNA 160..>6072 FT /gene="FAS2" FT CDS 196..5853 FT /codon_start=1 FT /transl_table=12 FT /gene="FAS2" FT /product="fatty acid synthase alpha subunit" FT /function="fatty acid biosynthesis" FT /note="cerulenin-binding site 2845..2862" FT /db_xref="GOA:P43098" FT /db_xref="HSSP:1FTF" FT /db_xref="InterPro:IPR016038" FT /db_xref="UniProtKB/Swiss-Prot:P43098" FT /protein_id="AAA34345.1" FT /translation="MKPEIEQELSHTLLTELLAYQFASPVRWIETQDVFLKQHNTERII FT EIGPSPTLAGMANRTIKAKYESYDAALSLQRQVLCYSKDAKEIYYKPDPADLAPKETPK FT QEESTPSAPAAATPTPAAAAAPTPAPAPASAGPVESIPDEPVKANLLIHVLVAQKLKKP FT LDAVPMTKAIKDLVNGKSTVQNEILGDLGKEFGSTPEKPEDTPLEELAEQFQDSFSGQL FT GKTSTSLIGRLMSSKMPGGFSITTARKYLESRFGLGAGRQDSVLLMALTNEPANRLGSE FT ADAKTFFDGIAQKYASSAGISLSSGAGSGAGAANSGGAVVDSAALDALTAENKKLAKQQ FT LEVLARYLQSRLKQGSLKSFIKEKEASAVLQKELDLWEAEHGEFYAKGIQPTFSALKSR FT TYDSYWNWARQDVLSMYFDIIFGKLTSVDRETINQCIQIMNRANPTLIKFMQYHIDHCP FT EYKGETYKLAKRLGQQLIDNCKQVLTEDPVYKDVSRITGPKTKVSAKGNIEYEETQKDS FT VRKFEQYVYEMAQGGAMTKVSQPTIQEDLARVYKAISKQASKDSKLELQRVYEDLLKVV FT ESSKEIETEQLTKDILQAATVPTTPTEEVDDPCTPSSDDEIASLPDKTSIIQPVSSTIP FT SQTIPFLHIQKKTKDGWEYNKKLSSLYLDGLESAAINGLTFKDKYVLVTGAGAGSIGAE FT ILQGLISGGAKVIVTTSRFSKKVTEYYQNMYARYGAAGSTLIVVPFNQGSKQDVDALVQ FT YIYDEPKKGGLGWDLDAIIPFAAIPENGNGLDNIDSKSEFAHRIMLTNLLRLLGAVKSK FT KPTDTRPAQCILPLSPNHGTFGFDGLYSESKISLETLFNRWYSEDWGSKLTVCGAVIGW FT TRGTGLMSANNIIAEGIEKLGVRTFSQKEMAFNILGLLTPEIVQLCQEEPVMADLNGGL FT QFIDNLKDFTSKLRTDLLETADIRRAVSIESAIEQKVVNGDNVDANYSKVMVEPRANMK FT FDFPTLKSYDEIKQIAPELEGMLDLENVVVVTGFAEVGPWGNSRTRWEMEAYGEFSLEG FT AIEMAWIMGFIKYHNGNLQGKPYSGWVDAKTQTPIDEKDIKSKYEEEILEHSGIRLIEP FT ELFNGYDPKKKQMIQEIVVQHDLEPFECSKETAEQYKHEHGEKCEIFEIEESGEYTVRI FT LKGATLYVPKALRFDRLVAGQIPTGWDARTYGIPEDTISQVDPITLYVLVATVEALLSA FT GITDPYEFYKYVHVSEVGNCSGSGMGGVSALRGMFKDRYADKPVQNDILQESFINTMSA FT WVNMLLLSSSGPIKTPVGACATAVESVDIGIETILSGKAKVVLVGGYDDFQEEGSYEFA FT NMNATSNSIEEFKHGRTPKEMSRPTTTTRNGFMEAQGSGIQVIMTADLALKMGVPIHAV FT LAMTATATDKIGRSVPAPGKGILTTAREHHGNLKYPSPLLNIKYRKRQLNKRLEQIKSW FT EETELSYLQEEAELAKEEFGDEFSMHEFLKERTEEVYRESKRQVSDAKKQWGNSFYKSD FT PRIAPLRGALAAFNLTIDDIGVASFHGTSTVANDKNESATINNMMKHLGRSEGNPVFGV FT FQKYLTGHPKGAAGAWMLNGAIQILESGLVPGNRNADNVDKLLEQYEYVLYPSRSIQTD FT GIKAVSVTSFGFGQKGAQAVVVHPDYLFAVLDRSTYEEYATKVSARNKKTYRYMHNAIT FT RNTMFVAKDKAPYSDELEQPVYLDPLARVEENKKKLVFSDKTIQSNQSYVGEVAQKTAK FT ALSTLNKSSKGVGVDVELLSAINIDNETFIERNFTGNEVEYCLNTAHPQASFTGTWSAK FT EAVFKALGVESKGAGASLIDIEITRDVNGAPKVILHGEAKKAAAKAGVKNVNISISHDD FT FQATAVALSEF" FT polyA_signal 5963..5969 FT /gene="FAS2" XX SQ Sequence 6072 BP; 1922 A; 1081 C; 1226 G; 1843 T; 0 other; ggatcctttt ttttttgggt aatattaaca atccagctta ggccatattg ttgggtgtcc 60 ttaaaaatta tgtgccaatt atttacttat atattgatat agctctcctt ttctcttttt 120 tatatttttc aaagtttttt ttattctttt actgtttatt caactaactt gtttttattt 180 ctcccccaat taacaatgaa accagaaatt gaacaagaat tatcccacac tttgttaact 240 gaattgttgg catatcaatt tgcttctcca gttagatgga ttgaaactca agatgtcttt 300 ttaaaacagc ataatactga aagaatcatc gaaattggtc cttcaccaac tttagctggt 360 atggccaata gaactatcaa agccaaatat gaatcctatg atgctgcttt atctttgcaa 420 cgacaagtct tgtgttactc caaagatgct aaggagattt actacaagcc agatccagca 480 gatcttgctc ctaaggaaac accaaagcaa gaagagagta ccccatcagc tcctgccgct 540 gccactccaa cacctgctgc tgccgctgct cctactccag caccagctcc tgcaagtgct 600 ggcccagttg aatctattcc agatgaacca gtcaaggcta acttgttaat ccatgttttg 660 gttgcacaaa aattaaagaa acctttagat gctgttccaa tgaccaaggc aattaaggat 720 ttggttaatg gtaaatccac tgttcaaaat gaaattcttg gtgacttggg taaggaattt 780 ggctctactc ctgaaaaacc ggaagacact ccattggaag aattagctga acaattccaa 840 gattcattca gcggtcaatt aggaaagact tctacttcat tgattggtag attaatgtcc 900 tcaaagatgc cgggtggatt ttccatcact actgctagaa agtatttgga atcaagattt 960 ggtttgggtg ctggtagaca agattctgtc ttgttgatgg ctttaacaaa tgaaccagct 1020 aatagattag gttctgaagc cgatgcaaaa actttctttg atggaattgc tcaaaaatac 1080 gcatcaagtg ctgggatctc cttgtcatca ggagcaggct ccggtgcagg cgccgcaaat 1140 agtggtggtg ctgttgttga tagtgctgcc ttagatgctt taacagctga aaacaagaaa 1200 ttagccaaac agcaattaga agttttagca agatacttgc aaagtcgact taaacaaggg 1260 agccttaaat cttttatcaa ggaaaaggaa gcttctgctg ttttacaaaa agagttagat 1320 ttgtgggaag cagaacacgg agaattctat gctaagggta tccaaccaac tttctccgca 1380 ttaaagtcta gaacttatga ctcctattgg aattgggccc gtcaagacgt tttatcaatg 1440 tatttcgaca ttatttttgg caagttaact tctgttgata gagaaaccat caaccaatgt 1500 attcaaatca tgaacagagc caatccaact ttaatcaagt ttatgcaata tcatatcgac 1560 cattgtccag aatataaagg tgaaacttat aaattggcca agagattggg tcaacaattg 1620 attgacaact gtaaacaagt tttgactgaa gatccagttt acaaagatgt ttccagaatt 1680 actggtccaa agactaaagt cagtgctaag ggtaacattg aatatgagga aactcaaaag 1740 gattcagtta gaaaatttga acaatatgtg tatgaaatgg cccaaggtgg tgctatgacc 1800 aaagttagtc aaccaactat tcaagaagat ttagctagag tttacaaggc tatttccaaa 1860 caagcttcca aagatagcaa attggaattg caaagagttt acgaagattt attgaaggtg 1920 gttgaaagtt ccaaggaaat cgaaaccgaa caattgacta aagatatttt acaagctgct 1980 acagttccaa caaccccaac agaggaagta gacgatcctt gtactccttc ttcggatgat 2040 gaaattgctt ctttaccaga taagacttct atcattcaac ctgtctcgtc tactattcca 2100 tctcaaacta ttccattttt gcacattcag aaaaagacca aagacggttg ggaatacaat 2160 aagaaattat cttctcttta cttggatgga ttggaatcag ctgccattaa tggtttaact 2220 ttcaaagaca agtatgtctt agttactggt gctggtgctg gctctattgg tgccgaaatt 2280 ttgcaaggtt taatcagtgg tggtgccaaa gttattgtca caacctctag attttccaag 2340 aaagttaccg agtattatca aaacatgtat gccagatatg gtgctgctgg gtctacttta 2400 attgttgttc cgttcaacca aggttctaaa caagatgttg atgcattggt tcaatacatt 2460 tatgatgagc caaagaaagg tggtttgggt tgggatttgg atgcaatcat tccatttgct 2520 gctattccag aaaatggtaa tggtctcgac aacattgatt ctaaatctga atttgcccac 2580 agaatcatgt tgaccaacct tttaagattg ttaggtgctg ttaaatccaa aaagcccact 2640 gacactagac ctgctcaatg tattttgcca ttatctccaa atcacggaac ttttggtttt 2700 gacgggttgt actctgaatc taaaatctca ttggaaacct tattcaacag atggtattct 2760 gaagattggg gatccaagtt gactgtttgt ggtgccgtaa ttgggtggac tagaggtaca 2820 ggtttgatga gtgccaataa cattattgct gaaggtattg aaaaattggg tgtcagaact 2880 ttctcccaaa aggaaatggc tttcaatatt ttaggtttat tgacaccaga aattgtacaa 2940 ttatgtcaag aagaaccagt tatggctgac ttgaatggtg gtttgcaatt cattgacaac 3000 ttgaaggatt tcacatctaa attaagaacc gacttgttgg aaactgcaga cattagaaga 3060 gctgtttcta ttgaatcagc tatcgagcaa aaagttgtca atggtgacaa tgtcgatgca 3120 aactactcaa aggttatggt tgaacctaga gccaacatga aatttgattt cccaactttg 3180 aaatcttatg atgaaatcaa acaaattgct ccagaattgg aaggtatgtt ggatttggaa 3240 aatgttgtcg ttgtgacagg ttttgctgaa gttggtccat ggggtaactc tagaaccaga 3300 tgggaaatgg aagcttatgg tgagttctca ttggaaggtg ccattgaaat ggcttggatt 3360 atgggtttca tcaagtatca taatggtaat ttgcaaggga aaccatactc tggatgggtt 3420 gatgccaaga ctcaaactcc aattgacgaa aaggatatca aatccaaata tgaagaagaa 3480 attttagaac attccggtat tagattgatt gagccagaat tgttcaatgg ctatgatcca 3540 aagaaaaaac aaatgattca agaaattgtt gttcaacacg atttagaacc atttgaatgt 3600 tctaaagaaa cagctgagca atacaaacac gaacacggag aaaaatgtga aatttttgaa 3660 attgaagaaa gtggtgaata cacagttaga atcttgaaag gtgcaacatt gtacgttccg 3720 aaagctttga gatttgatag attagttgct ggtcaaattc caactggttg ggacgctcgt 3780 acctatggta tcccagaaga cactattagt caagttgatc caatcacttt gtacgtgttg 3840 gttgccactg ttgaagcctt gttgtctgct ggtattactg atccatatga attctacaaa 3900 tacgttcatg tgtctgaagt tggtaactgt tctggttccg gtatgggagg tgtctctgct 3960 ttgagaggaa tgttcaaaga tagatatgct gacaaaccag ttcaaaatga cattttgcaa 4020 gaatcattta tcaacactat gtctgcttgg gtcaatatgt tgttgttgtc ttcctctggt 4080 ccaatcaaga caccagtcgg tgcttgtgcc actgctgttg aatcggttga cattggtatt 4140 gaaacaattt tgtctggtaa agctaaagta gttttggtag gtggttacga tgacttccaa 4200 gaagaagggt cttatgaatt cgccaatatg aatgctactt ctaattctat tgaagagttc 4260 aaacacggaa gaacaccaaa ggaaatgtca agaccaacta ctactaccag aaatggtttc 4320 atggaagctc aaggttctgg tattcaagtt atcatgactg ctgatttggc tctcaagatg 4380 ggtgttccaa tccacgctgt attggccatg actgctactg ccactgataa gattggtaga 4440 tctgttccag caccaggtaa aggtattttg accactgcca gagaacatca tggcaacttg 4500 aagtacccat ctccactttt gaacatcaag tacaggaaga gacaattgaa caaaagattg 4560 gaacaaatca aatcttggga agaaacagaa ctttcttact tgcaagaaga agccgagttg 4620 gccaaagaag aatttggtga cgaattttct atgcatgagt tcttgaaaga gagaactgaa 4680 gaagtgtacc gtgaatcaaa gagacaagtt tctgatgcta agaaacaatg gggtaattca 4740 ttctacaagt ctgatccaag aattgctcca ttgagaggag cattggctgc cttcaactta 4800 accatcgatg atattggtgt tgcatccttc catggtactt ccaccgttgc taacgataag 4860 aatgaatctg ccacaatcaa caatatgatg aaacacttgg gtagatccga aggtaaccca 4920 gtatttggtg ttttccaaaa atacttgaca ggtcatccaa aaggtgcagc tggtgcttgg 4980 atgttgaatg gtgccattca aattcttgag tctggtcttg ttccaggtaa cagaaatgcg 5040 gataatgttg ataagctttt agaacaatac gaatatgtat tgtacccatc aagatcaatt 5100 caaaccgatg gtattaaagc cgtttctgtt acatcatttg gtttcggtca aaaaggtgca 5160 caagccgttg ttgttcatcc agattactta tttgctgttt tggatagatc cacttatgaa 5220 gaatatgcta ctaaggtctc tgctagaaat aaaaagacct accgttacat gcacaatgca 5280 atcaccagaa acactatgtt tgttgccaaa gacaaagctc catatagtga cgaattggaa 5340 caaccagttt acttggatcc attggctcgt gttgaagaaa acaagaaaaa gttggtattc 5400 agtgacaaaa caattcaatc gaaccaatct tatgttggag aagttgctca aaaaactgct 5460 aaggcattgt ctactttaaa caaatcatca aagggagttg gtgtagatgt tgaattgttg 5520 tcagcaatca atatcgacaa tgaaaccttt attgaaagaa actttactgg taatgaagtt 5580 gaatactgtt tgaatactgc tcacccacaa gcttcattca ctggaacttg gtcagcaaag 5640 gaagctgttt tcaaagcctt gggtgttgaa tcaaaaggtg ctggagcaag cttgattgat 5700 attgaaatca ctcgtgacgt taatggtgct cctaaagtaa ttttgcatgg tgaggccaaa 5760 aaagctgctg ctaaagctgg tgttaaaaat gtcaatattt caatttctca tgatgatttc 5820 caagctactg ctgttgcttt aagtgaattt taaaattagt agtgtttaga aatattcgtg 5880 tatatctgat caaaaacttt tttgattttt aatatatgtc cggttgtaca attttttttt 5940 ctgttgattt aaactgatct cattattttg ttctctcaca gctcacagcc tacaaccata 6000 aaaaaagccc aacactcact tttgctcact ggttcaccac cactacggaa aaaataagaa 6060 caacaaataa aa 6072 // |
|