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EBI DbfetchID L23970; SV 1; linear; unassigned DNA; STD; PRO; 13914 BP. XX AC L23970; XX DT 10-SEP-1993 (Rel. 36, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 9) XX DE Azotobacter vinelandii hox and hyp operons, complete cds. XX KW hoxG gene; hoxK gene; hoxL gene; hoxM gene; hoxO gene; hoxQ gene; KW hoxR gene; hoxT gene; hoxV gene; hoxZ gene; hypA gene; hypB gene; KW hypC gene; hypD gene; hypE gene; hypF gene; membrane-bound cytochrome b; KW NiFe-hydrogenase subunit; rubredoxin. XX OS Azotobacter vinelandii OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Azotobacter. XX RN [1] RP 1-13914 RX DOI; 10.1016/0378-1119(90)90342-O RX PUBMED; 2265761. RA Menon A.L., Stults L.W., Robson R.L., Mortenson L.E.; RT "Cloning, sequencing and characterization of the [NiFe]hydrogenase-encoding RT structural genes (hoxK and hoxG) from Azotobacter vinelandii"; RL Gene 96(1):67-74(1990). XX RN [2] RP 1-13914 RX DOI; 10.1016/0167-4781(92)90111-C RX PUBMED; 1581355. RA Chen J.C., Mortenson L.E.; RT "Two open reading frames (ORFs) identified near the hydrogenase structural RT genes in Azotobacter vinelandii, the first ORF may encode for a polypeptide RT similar to rubredoxins"; RL Biochim. Biophys. Acta 1131(1):122-124(1992). XX RN [3] RP 1-13914 RX DOI; 10.1016/0167-4781(92)90077-D RX PUBMED; 1610901. RA Chen J.C., Mortenson L.E.; RT "Identification of six open reading frames from a region of the Azotobacter RT vinelandii genome likely involved in dihydrogen metabolism"; RL Biochim. Biophys. Acta 1131(2):199-202(1992). XX RN [4] RP 1-13914 RX PUBMED; 1624446. RA Menon A., Mortenson L.E., Robson R.L.; RT "Nucleotide sequences and genetic analysis of hydrogen oxidation (hox) RT genes in Azotobacter vinelandii"; RL J. Bacteriol. 174(14):4549-4557(1992). XX RN [5] RP 1-13914 RX DOI; 10.1006/jmbi.1994.1149 RX PUBMED; 7906310. RA Garg R.P., Menon A.L., Jacobs K., Robson R.M., Robson R.L.; RT "The hypE gene completes the gene cluster for H2-oxidation in Azotobacter RT vinelandii"; RL J. Mol. Biol. 236(1):390-396(1994). XX FH Key Location/Qualifiers FH FT source 1..13914 FT /organism="Azotobacter vinelandii" FT /mol_type="unassigned DNA" FT /db_xref="taxon:354" FT gene 149..1225 FT /gene="hoxK" FT CDS 149..1225 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxK" FT /product="NiFe-hydrogenase subunit" FT /db_xref="GOA:P21950" FT /db_xref="InterPro:IPR001821" FT /db_xref="InterPro:IPR006137" FT /db_xref="InterPro:IPR006311" FT /db_xref="InterPro:IPR017909" FT /db_xref="UniProtKB/Swiss-Prot:P21950" FT /citation=[1] FT /protein_id="AAA19498.1" FT /translation="MSRLETFYDVMRRQGITRRSFLKYCSLTAAALGLGPAFAPRIAHA FT METKPRTPVLWLHGLECTCCSESFIRSAHPLVKDVVLSMISLDYDDTLMAAAGHQAEAA FT LEETMRKYKGEYILAVEGNPPLNEDGMFCIVGGKPFIEQLRHVAKDAKAVIAWGSCASW FT GCVQAARPNPTQAVPIHKVITDKPIVKVPGCPPIAEVMTGVITYMLTFGKLPELDRQGR FT PKMFYGQRIHDKCYRRPHFDAGQFVEHWDDEGARKGYCLYKVGCKGPTSYNACSTVRWN FT EGTSFPIQAGHGCIGCSEDGFWDKGSFYERLTTIPQFGIEKNADEIGAAVAGGVGAAIA FT AHAAVTAIKRLQNKGDRP" FT gene 1222..3030 FT /gene="hoxG" FT CDS 1222..3030 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxG" FT /product="NiFe-hydrogenase subunit" FT /db_xref="GOA:P21949" FT /db_xref="InterPro:IPR001501" FT /db_xref="InterPro:IPR018194" FT /db_xref="UniProtKB/Swiss-Prot:P21949" FT /citation=[1] FT /protein_id="AAA19499.1" FT /translation="MSSLPNASQLDKSGRRIVVDPVTRIEGHMRCEVNVDASNVITNAV FT STGTMWRGLEVILKGRDPRDAWAFVERICGVCTGTHALTSVRAVEDALDIRIPYNAHLI FT RNLMDKTLQVHDHIVHFYHLHALDWVNPVNALKADPKATSALQQAVSPAHAKSSPGYFR FT DVQTRLKKFVESGQLGLFSNGYWDNPAYKLPPEADLMAVAHYLEALDLQKDIVKIHTIF FT GGKNPHPNYMVGGVACAINLDDVGAAGAPVNMTSLNFVLERIHEAREFTRNVYLPDVLA FT VAGIYKDWLYGGGLAAHNLLSYGTFTKVPYDKSSDLLPAGAIVGGNWDEVLPVDVRDPE FT EIQEFVSHSWYSYADETKGLHPWDGVTEPKFELGPNTKGSRTHIQEIDEAHKYSWIKAP FT RWRGHAMEVGPLARYIIAYASGREYVKEQVDRSLAAFNQSTGLNLGLKQFLPSTLGRTL FT ARALECELAVDSMLDDWQALVGNIKAGDRATANVEKWDPSTWPKEAKGVGINEAPRGAL FT GHWIRIKDGKIENYQAIVPTTWNGTPRDHLGNIGAYEAALLNTRMERPDEPVEILRTLH FT SFDPCLACSTHVMSPDGQELTRVKVR" FT gene 3047..3769 FT /gene="hoxZ" FT CDS 3047..3769 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxZ" FT /product="membrane-bound cytochrome b" FT /db_xref="GOA:P23000" FT /db_xref="InterPro:IPR000516" FT /db_xref="InterPro:IPR011577" FT /db_xref="InterPro:IPR016174" FT /db_xref="UniProtKB/Swiss-Prot:P23000" FT /citation=[1] FT /protein_id="AAA19500.1" FT /translation="MALEKSLETGDGQEKVRKQTAVYVYEAPLRLWHWVTALSIVVLGV FT TGYFIGAPLPTMPGEAMDNYLMGYIRFAHFAAGYVLAIGFLGRVYWAFVGNHHARELFL FT VPVHRKAWWKELWHEVRWYLFLEKTPKKYIGHNPLGQLAMFCFFVVGAVFMSVTGFALY FT AEGLGRDSWADRLFGWVIPLFGQSQDVHTWHHLGMWYLVVFVMVHVYLAVREDIVSRQS FT LISTMVGGWRMFKDDRPD" FT gene 3831..4454 FT /gene="hoxM" FT CDS 3831..4454 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxM" FT /db_xref="GOA:P40591" FT /db_xref="InterPro:IPR000671" FT /db_xref="InterPro:IPR004419" FT /db_xref="UniProtKB/Swiss-Prot:P40591" FT /citation=[4] FT /protein_id="AAA19501.1" FT /translation="MTAPNILILGIGNLLWADEGFGVRCVELLNERYRFPDGVRLMDGG FT TQGIYLVQHVQQADCLIVFDAVDYGLAPGTLKIVRDDEVPRFMGAKRMSLHQTGFQDVL FT ALAAFSGAYPRELLLIGVQPEELEDFGGSLREPVRAQLEPALRVALEFLAERGVVAAAR FT DGDAERLAPAPLALGRYEAGRPAEELAYRHGDIRFIPQQPLEDD" FT gene 4458..4778 FT /gene="hoxL" FT CDS 4458..4778 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxL" FT /db_xref="InterPro:IPR001109" FT /db_xref="InterPro:IPR019812" FT /db_xref="UniProtKB/Swiss-Prot:P40592" FT /citation=[4] FT /protein_id="AAA19502.1" FT /translation="MCIGIPLRVLECAPGRALCGDENGVRWIDTRLVEPPAPGDWLLVF FT LDAAREILDAGRAARIREALRALQAVQAGDPAALAGLFADLDREPQLPPHLQAQLPPKE FT PT" FT gene 4775..5221 FT /gene="hoxO" FT CDS 4775..5221 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxO" FT /db_xref="InterPro:IPR010893" FT /db_xref="UniProtKB/Swiss-Prot:P40593" FT /citation=[4] FT /protein_id="AAA19503.1" FT /translation="MIHPLIQRLTTTLGYPLLDADGLDRQVRTQPFSVLFFAGDPQRFP FT EALDVAVILPELVKAFPQLAPALIAGADEARLQGRYGFSVWPSLVFLAGERYLGCLSRV FT LDWGEYLERIPAILAGENEDLPRIPVLSPESGTPSCSPMETSES" FT gene 5218..6069 FT /gene="hoxQ" FT CDS 5218..6069 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxQ" FT /db_xref="InterPro:IPR006894" FT /db_xref="UniProtKB/Swiss-Prot:P40594" FT /citation=[4] FT /protein_id="AAA19504.1" FT /translation="MNDDLPILPPGFGPGSHGEEERPDCPSMPRAMRRFERPALPEPGQ FT LSGHPIALALLERLQEALGAYRIGEQSRVIGLDRQPKADLKLLQQILGEGEVAIQVGGQ FT RPARIQETVLAGVWWVQLQIGRGEVVGQWLEVADVPALVRRRAFAETRWPQLGELPDGL FT LNAGPVLVELLDAAKRHAERALATPHAVNLSLLPFSPEDRRFLAERLGEGSVTLLSRGY FT GNCRIASTATPGIWCVQYFNSSDRLILDTLEVTGIPQVACAAQEDIDDSAERLREIREA FT LE" FT gene 6066..6284 FT /gene="hoxR" FT CDS 6066..6284 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxR" FT /product="rubredoxin" FT /db_xref="GOA:P30778" FT /db_xref="InterPro:IPR001052" FT /db_xref="InterPro:IPR004039" FT /db_xref="InterPro:IPR018527" FT /db_xref="UniProtKB/Swiss-Prot:P30778" FT /citation=[4] FT /citation=[2] FT /protein_id="AAA19505.1" FT /translation="MSARFEGSYLGDATRLADDAVLECKICWQRYDPAEGDPVWQIPPG FT TPFAALPAHWRCPRCDGDREQFMVVDG" FT gene 6291..6752 FT /gene="hoxT" FT CDS 6291..6752 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxT" FT /db_xref="UniProtKB/Swiss-Prot:P30781" FT /citation=[4] FT /citation=[2] FT /protein_id="AAA19506.1" FT /translation="MHGREAIEAHYRVAGARMAGLPVYNPALTVELLGWRAVEGVGALG FT VLITPWCMNLFWQPPADAELPASGERAVLSLPSGDYECTLHEDERLGRHASASLCSPMQ FT DFPGQAEARAMAGEVLRLILAVPEAGPEPSRSGLLSRRALFRRALGGAS" FT gene 6749..7795 FT /gene="hoxV" FT CDS 6749..7795 FT /codon_start=1 FT /transl_table=11 FT /gene="hoxV" FT /db_xref="UniProtKB/Swiss-Prot:P40597" FT /citation=[2] FT /citation=[3] FT /protein_id="AAA19507.1" FT /translation="MSALEALAGRLHVEVRLQDGVIRAVDTRLQRPLPQISRLLVGQTA FT EAALRRLPLLFGLCAAAQQVAALRALERAAGWAAIAEVEEGRTRLGELESIRESLLRLV FT QVWELPVPLERLKALLALCRRAAARLQALTAFRAAPLPADAELEGTLAALAAAWADLQP FT PAPADWLRPRLDRWQEVALGGPPPQAFTADELPALLAQLRASDARAEIAGQPRLGGPAA FT SAGAQATASAQIEQHVGALLRRTAQAIDSLQSPPAPPAVAGLAAGEGVGLARTARGWLL FT HRVCLDDGAVGTWQLLAPTDWNFHADGPLRRRLCGVRVAAGEVEALLRELILALDPCVA FT FEVKIVHA" FT gene 7788..8129 FT /gene="hypA" FT CDS 7788..8129 FT /codon_start=1 FT /transl_table=11 FT /gene="hypA" FT /db_xref="GOA:P31879" FT /db_xref="InterPro:IPR000688" FT /db_xref="InterPro:IPR020538" FT /db_xref="UniProtKB/Swiss-Prot:P31879" FT /citation=[3] FT /protein_id="AAA19508.1" FT /translation="MHEMSIAEGIVQLLEEQAVAQDFTRVRALWLEIGPLAAIEVESLR FT FCFEAVTRGSLAEGARLEIVELPGRAWCLGCNASVAIRRRYDACPQCGSHRLQVTQGDE FT LRVKELEVE" FT gene 8132..9043 FT /gene="hypB" FT CDS 8132..9043 FT /codon_start=1 FT /transl_table=11 FT /gene="hypB" FT /db_xref="GOA:P31880" FT /db_xref="InterPro:IPR003495" FT /db_xref="InterPro:IPR004392" FT /db_xref="InterPro:IPR012202" FT /db_xref="UniProtKB/Swiss-Prot:P31880" FT /citation=[3] FT /protein_id="AAA19509.1" FT /translation="MCTVCGCAEGETRIEGEHHHHGHDHHHHEHPFVRRPAPAEAAPPA FT AGGPNLHFGQGPARAHAPGLSQSRMLRIEQDILGKNDRYAAENRARFEALSLFVLNLVS FT SPGSGKTSLLTRTIELLGRRRPLAVIEGDQQTDHDAARIRATGVPAVQINTGKGCHLDA FT HMVGHALARLDDLEGGLLFIENVGNLVCPAAFDLGEAHKVAILSVTEGEDKPLKYPDMF FT HAADLMLLNKTDLLPHLDFDVEACIAYARRVNPDIEVIRVSARSGEGMGEWLAWIERQR FT GTRLRARIDALREQARALEALL" FT gene 9103..11370 FT /gene="hypF" FT CDS 9103..11370 FT /codon_start=1 FT /transl_table=11 FT /gene="hypF" FT /db_xref="GOA:P40596" FT /db_xref="InterPro:IPR001792" FT /db_xref="InterPro:IPR004421" FT /db_xref="InterPro:IPR006070" FT /db_xref="InterPro:IPR011125" FT /db_xref="InterPro:IPR017945" FT /db_xref="InterPro:IPR017968" FT /db_xref="UniProtKB/Swiss-Prot:P40596" FT /citation=[3] FT /protein_id="AAA19510.1" FT /translation="MRPCVHRLATSLGLAGEVRNTGAGVRIDLLGPPQALAEFERRLPD FT ELPPLARLDAIQREPLPAGTRFAGFAIAASRDERRGALAPPPDAAVCPACLEELFDPHD FT RRWRHPFINCTHCGPRYSLIRRLPYDRVQTSLAGFELCPECRREYEDPADRRFHAQPIA FT CPACGPRLCCEDASGRRLSGDPIERALAALARGEILALRGVGGFHLACDARNAGAVAEL FT RRRKRRPAKPFALMAANPASLQALVELNENGLAELSGPAAPVVLLRKRPAADDLLAAGV FT APDLAWLGAMLPHSPLHWLLFHEAAGRPAGTGWAAAPQDLLLVMTSANLSGAPPITGNA FT EARERLAGIADLWLLHDREILNRCDDSVVSALGRAPLVIRSGRGLAPLEIPLARGGPSI FT LALGGQLKNAVCLTRGDRAWLSPHNGDLDDADTCRALERTVARLGELLGIRPERVACDL FT HPDFFASRFARDYAERHGLPLHPIQHHHAHIAATMAEHGLAEPVLGLALDGFGLGADGR FT LRGGELLRVAADGCAWLGELNPLPLPGGDQASREPWRMAAGALHALGRGGEIATRFAAE FT PGNAAIARMLERGFNCPPSSSAGRLFDAAAGLLGLGGRQRYEAEAALRLESRVVGLPER FT VPALWRIDDDNRLDLLPLLARLADMRDTRAGAELFHGVLIEALAIWAARAAEATGLHRV FT ALGGGCFLNTVLRDGLCARLRAAGLTPLLARRAPLNDGGLALGQAWAVLLAADIPSTRG FT QA" FT gene 11370..11624 FT /gene="hypC" FT CDS 11370..11624 FT /codon_start=1 FT /transl_table=11 FT /gene="hypC" FT /db_xref="InterPro:IPR001109" FT /db_xref="InterPro:IPR019812" FT /db_xref="UniProtKB/Swiss-Prot:P31881" FT /citation=[3] FT /protein_id="AAA19511.1" FT /translation="MCLAIPVRIEELLDEQSAVACIGGLRKTINVALLDDLKVGDYVIL FT HVGFALQKLDEAEAQRTLALLAELGRLAEAEQAAQGEAP" FT gene 11621..12760 FT /gene="hypD" FT CDS 11621..12760 FT /codon_start=1 FT /transl_table=11 FT /gene="hypD" FT /db_xref="GOA:P31882" FT /db_xref="InterPro:IPR002780" FT /db_xref="UniProtKB/Swiss-Prot:P31882" FT /citation=[3] FT /protein_id="AAA19512.1" FT /translation="MKYVDEFRDGATARQLAARIAAEADPKRQYRLMEFCGGHTHAIFR FT YGIPDLLPANVRLIHGPGCPVCVMPIGRLDMAIELARRPGVILCTYGDMLRVPASGRVS FT LLKARAEGAAVRMLYSPIEALKLAQDNPDRDVVFFAIGFETTTPPTALVIEQAQRLGLK FT NFSVFCNHVLTPAAMHAILATPEARAGTLQLDGFIGPAHVSTVIGSDAYAPFPRQYGTP FT LVIAGFEPLDLLQALLMLVRQLNEGRAEVENQFTRAVTAGGNLKAKALTGRIFELRESF FT EWRGLGALPNSALRIREAFAEFDAERRFALEARSGLENKACECPAILRGAKSPRDCKLF FT GNPCSPDNPLGSCMVSSEGACAAWYAYGRQRQAVVAVAR" FT gene 12757..13782 FT /gene="hypE" FT CDS 12757..13782 FT /codon_start=1 FT /transl_table=11 FT /gene="hypE" FT /db_xref="GOA:P40595" FT /db_xref="InterPro:IPR000728" FT /db_xref="InterPro:IPR010918" FT /db_xref="InterPro:IPR011854" FT /db_xref="InterPro:IPR016188" FT /db_xref="UniProtKB/Swiss-Prot:P40595" FT /protein_id="AAA19513.1" FT /translation="MSRLDLRNGSVEMVHGSGGRAMGQLIEELFARALRNEWLDQRNDQ FT AQFELPPGRVVMATDSHVISPLFFPGGDIGSLAVHGTINDVAMAGARPCYLAAGFILEE FT GFPLADLARIVESMAAAAREAGVPVVTGDTKVVEHGKGDGVFITTTGVGVVPPGLHLSG FT DQARPGDRILLSGSIGDHGVTILSLREGLGFEADIGSDSQALHGLVAAMLAAVPEIRCL FT RDPTRGGLGNTLNELARQSGVGMQLVERAIPVREPVRAACEFLGLDPLYVANEGKLIAI FT CPAERAERLLEAMRAHPQGREAAIIGTVVADEHRFVQMETPFGGSRMVDWLSGEQLPRI FT C" XX SQ Sequence 13914 BP; 2052 A; 5020 C; 4815 G; 2027 T; 0 other; tgtatcaagc catgacaaaa acatggcatt ggcgcattat tcgtgcggtt ttcattcagc 60 aaccgtgggc catacaaccg gcgcgccgtc atagccgaag gacggtgcgc aggggcgccg 120 ataacgacct ggccacaagg gtaacggcat gtctcgactc gaaactttct atgacgtgat 180 gcggcgtcag ggcatcacgc gccgcagctt tctcaaatat tgcagcctga ccgccgcggc 240 cctgggcctc ggcccggcct tcgccccgcg gatcgcccac gcgatggaaa ccaagccgcg 300 cactccggtg ctctggctgc acggcctgga gtgcacctgc tgctccgagt cgttcatccg 360 ttcggcccac ccgctggtca aggacgtggt gctgtcgatg atctcgctgg actacgacga 420 caccctgatg gccgccgccg gccaccaggc cgaggccgcc ctcgaagaga ccatgcgcaa 480 gtacaagggc gagtacatcc tcgccgtgga gggcaacccg ccgctcaacg aggacggcat 540 gttctgcatc gtcggcggca agccgttcat cgagcagctc aggcatgtgg cgaaggacgc 600 caaggcggtg atcgcctggg gcagttgcgc cagttggggc tgcgtgcagg cggcccggcc 660 caacccgacc caggcggtgc cgatccacaa ggtcatcacc gacaagccga tcgtcaaggt 720 gcccggctgc ccgccgatcg ccgaggtgat gaccggggtg atcacctaca tgctgacctt 780 cggcaagctg cccgagctgg accgccaggg gcggccgaag atgttctacg gccagcgcat 840 ccacgacaag tgctaccgcc gcccgcactt cgacgccggc cagttcgtcg agcactggga 900 cgacgagggc gcgcgcaagg gctactgcct gtacaaggtc ggctgcaagg gcccgaccag 960 ctacaacgcc tgctcgacgg tgcgctggaa cgagggcact tccttcccga tccaggccgg 1020 ccacggctgc atcggctgct cggaggacgg tttctgggac aagggctcgt tctatgaacg 1080 cctgaccacc attccgcagt tcggcatcga gaagaacgcc gacgaaatcg gcgccgccgt 1140 cgccggcggg gtcggcgcgg ccatcgccgc gcatgccgcg gtcaccgcca tcaagcgcct 1200 gcagaacaag ggggatcgcc catgagcagc ctgccgaacg ccagccaact ggacaagtcc 1260 ggcaggcgca tcgtcgtcga cccggtgacc cgcatcgagg gccacatgcg ctgcgaggtc 1320 aacgtcgacg ccagcaacgt gatcaccaac gccgtctcca ccggcaccat gtggcgcggc 1380 ctggaggtca tcctcaaggg ccgcgacccg cgcgacgcct gggccttcgt cgagcgcatc 1440 tgcggcgtct gcaccggcac ccatgcgctg acctcggtgc gcgcggtgga ggatgccctg 1500 gacatccgca tcccctacaa cgcccacctg atccgcaacc tgatggacaa gacgctgcag 1560 gtgcacgacc acatcgtgca cttctaccac ctgcacgcgc tggactgggt caacccggtc 1620 aacgccctga aggccgatcc caaggctacc tccgccctgc agcaggcggt ttcgccggcc 1680 catgccaagt ccagccccgg ctacttccgc gacgtgcaga cgcgcctgaa gaagttcgtc 1740 gagagcggcc agctcggcct gttctccaac ggctactggg acaatccggc ctacaagctg 1800 ccgcccgagg cggacctgat ggccgtggcc cactacctgg aggcgctgga cctgcagaag 1860 gacatcgtca agatccatac catcttcggc ggcaagaacc cgcatccgaa ctacatggtc 1920 ggcggcgtgg cctgcgccat caacctggac gacgtcggcg ccgccggcgc gccggtcaac 1980 atgaccagcc tgaacttcgt cctcgaacgc atccacgagg cccgcgagtt caccaggaac 2040 gtctacctgc cggacgtgct ggcggtcgcc gggatctaca aggactggct gtacggcggc 2100 ggtctggccg cgcacaacct gctgtcctac ggcaccttca ccaaggtgcc ctacgacaag 2160 tccagcgacc tgttgccggc cggcgccatc gtcggcggca attgggacga ggtgctgccg 2220 gtcgacgtgc gcgatcccga ggagatccag gagttcgtca gccactcctg gtacagctac 2280 gccgacgaaa ccaaggggct gcatccctgg gacggcgtca ccgagccgaa attcgagctc 2340 ggcccgaaca ccaagggcag ccgcacccac atccaggaaa tcgacgaggc gcacaagtac 2400 agctggatca aggcgccgcg ctggcgcggc cacgctatgg aggtcggccc gctggcacgt 2460 tacatcatcg cctacgcttc gggccgcgaa tacgtgaagg aacaggtcga ccgctcgctg 2520 gccgccttca accagagcac cggcctgaac ctcggcctca agcagttcct gccctcgacc 2580 ctcggccgca ccctggcgcg cgccctggag tgcgagctgg cggtggacag catgctcgac 2640 gactggcagg ccctggtcgg caacatcaag gccggcgacc gcgccaccgc caacgtcgag 2700 aagtgggacc cgagcacctg gccgaaggag gccaagggcg tgggcatcaa cgaggcgccg 2760 cgcggcgccc tgggccactg gatcaggatc aaggacggca agatcgagaa ctaccaggcg 2820 atcgtgccga ccacctggaa cggcaccccg cgcgaccatc tgggcaacat cggcgcctac 2880 gaggccgcgc tgctcaacac caggatggag cgcccggacg agccggtgga gatcctgcgc 2940 accctgcaca gcttcgaccc ctgcctggcc tgttcgaccc acgtgatgtc gccggacggc 3000 caggagctga cccgggtgaa ggtccgctga accggaggat tgcgcgatgg cactggaaaa 3060 atccctggaa accggcgacg gccaggagaa ggtccgcaag cagaccgcgg tgtacgtcta 3120 cgaggcgccg ctgcgcctct ggcactgggt cacggcgctg tccatcgtcg tgctcggcgt 3180 gaccggctac ttcatcggcg cgccgctgcc gacgatgccc ggcgaggcga tggacaacta 3240 cctgatgggc tacatccgct tcgcccactt cgccgccggc tacgtgctgg cgatcggctt 3300 cctcggccgg gtctactggg ccttcgtcgg caaccaccac gcccgcgagc tgttcctcgt 3360 gccggtgcac cgcaaggcct ggtggaagga gctgtggcac gaggtgcgct ggtacctgtt 3420 cctggaaaag accccgaaga agtacatcgg ccacaacccc ctgggccagt tggcgatgtt 3480 ctgcttcttc gtggtcggcg cggtgttcat gagcgtcacc ggcttcgccc tctacgccga 3540 ggggctgggg cgggacagct gggccgaccg gctgttcggc tgggtgatcc cgctgttcgg 3600 ccagagccag gacgtgcaca cctggcacca cctgggcatg tggtacctcg tcgtcttcgt 3660 catggtgcat gtctacctgg ccgtgcgcga agacatcgtt tcccggcagt cgctgatctc 3720 caccatggtc ggcggctggc ggatgttcaa ggacgaccgg ccggattgag ccccgtgtcg 3780 tcccttccgt ccgggccggt ccgccggctc cgggcgacgg tgaggcaacg atgacagccc 3840 ccaacatcct cattctcggt atcggcaacc tgctctgggc ggacgaaggc ttcggcgtgc 3900 gttgcgtgga gctgctcaac gagcgctatc gcttccccga cggggtgcga ctgatggacg 3960 gcggcaccca gggcatctac ctggtgcagc acgtccagca ggccgactgc ctgatcgtct 4020 tcgacgccgt cgactacggc ctggcgcccg gcaccctgaa gatcgtgcgc gacgacgagg 4080 tgccccgctt catgggcgcc aagcgcatga gcctgcacca gaccggcttc caggacgtgc 4140 tggcgctggc cgcgttcagc ggcgcctacc cgcgcgagct gctgctgatc ggcgtgcagc 4200 ccgaggaact ggaagacttc ggcggcagcc tgcgcgagcc ggtgcgcgcc cagctggagc 4260 cggcgctgcg ggtcgccctg gaattcctcg ccgagcgcgg ggtggtcgcc gcagcgcgcg 4320 acggcgacgc cgagcgcctg gctccggcgc cactggccct gggccgctac gaggccggcc 4380 gcccggccga ggaactggcc taccgccacg gcgatatccg cttcatcccg cagcagcctc 4440 tggaggacga ctgagccatg tgcatcggta ttcccctgcg ggtgctggaa tgcgcgccgg 4500 gccgcgccct gtgcggcgac gagaacggcg tgcggtggat cgacacgcgg ctggtcgagc 4560 cgccggcgcc cggcgactgg ctgctggtgt tcctcgacgc cgcccgcgaa atcctcgacg 4620 ccgggcgcgc cgcgcggatc cgcgaggccc tgcgcgcgct gcaggccgta caggcgggcg 4680 atccggccgc gctcgccggc ctgttcgccg acctcgaccg cgagccgcaa ctcccgcccc 4740 acctgcaggc gcaactgccg cccaaggaac cgacatgatc catcccctga tccagcgtct 4800 gaccacgacg ctcggctacc ccctgctgga tgccgacggc ctcgaccgcc aggtgcggac 4860 gcagccgttc tccgtgctgt tcttcgccgg cgatccgcag cgctttcccg aggcgctcga 4920 cgtcgcggtg atcctgccgg aactggtcaa ggccttcccg cagctcgctc ccgcgttgat 4980 cgccggcgcg gacgaggccc gtctgcaggg gcgctacggt ttctccgtct ggccgagcct 5040 ggtgttcctc gcgggggagc gctacctggg ctgcctgtcg cgggtactgg actggggcga 5100 atacctggag cgcatcccgg cgatcctcgc cggcgagaac gaagacctgc cacgcattcc 5160 cgtgctgtcg ccggagagcg gcacaccttc ctgcagcccg atggagacca gtgaatcatg 5220 aacgacgacc tgcccattct cccgcccggc ttcggccccg gctcgcatgg cgaagaggag 5280 cggcccgact gcccgtcgat gccgcgcgcc atgcgcaggt tcgaacgtcc cgcgctgccg 5340 gagcccggac aactgagcgg acaccccatc gccctggcgc tgctggagcg gctgcaggag 5400 gcgctgggcg cctaccggat cggcgagcag agccgggtga tcggcctcga ccgccagccc 5460 aaggccgacc tgaagctgct ccagcagatc ctcggcgaag gcgaggtggc gatccaggtc 5520 ggcggccagc gccccgcgcg catccaggaa accgtgctgg ccggggtctg gtgggtgcaa 5580 ctgcagatcg gccggggcga ggtcgtcggc cagtggctgg aggtggccga cgttcccgct 5640 ctggtgcgcc gccgggcctt cgccgaaacc cgctggccgc agctcggtga gttgccggac 5700 ggcctgctca acgccggccc ggtgctggtg gagttgctcg acgcggcgaa gcggcatgcc 5760 gagcgcgcgc tcgccacgcc ccacgcggtc aacctgtcgt tgctgccgtt ctccccggag 5820 gaccggcgct ttctcgccga aaggctcggc gaggggtcgg tgaccctgct ctcgcgcggc 5880 tacggcaact gccgcatcgc cagcactgcc acccccggca tctggtgcgt gcagtacttc 5940 aacagcagcg accggctgat cctcgacacc ctggaggtga cgggcatccc gcaggtggcc 6000 tgcgccgccc aggaggacat cgacgactcc gccgagaggc tgcgcgagat ccgcgaggct 6060 ctggagtgag cgcgcgcttc gagggcagct acctgggcga cgccacgcgc ctggcggacg 6120 acgccgtgct cgaatgcaag atctgctggc agcgctacga ccccgccgag ggcgatccgg 6180 tctggcagat cccgccgggc acgcccttcg ccgcgctgcc ggcgcactgg cgctgcccgc 6240 gctgcgacgg cgaccgcgag cagttcatgg tcgtggacgg ctgaaggccc atgcacggcc 6300 gcgaagccat cgaagcccac taccgggtgg ccggcgcgcg catggccggg ctgccggtgt 6360 acaacccggc gctcaccgtg gagctgctcg gctggcgcgc ggtcgagggc gtcggtgcgc 6420 tcggcgtgct gatcaccccc tggtgcatga acctgttctg gcagccgccg gccgatgccg 6480 aactgccggc cagcggcgag cgcgcggtgt tgtcgctgcc ctccggcgac tacgaatgca 6540 ccctgcacga ggacgagcgc ctcggccgcc atgccagcgc ctcgctgtgc tcgccgatgc 6600 aggattttcc cggccaggcc gaggcgcggg cgatggccgg ggaggtgctg cggctgatcc 6660 tcgccgtgcc ggaggccggg cccgaaccgt cgcggagcgg tttgttgagc cgccgcgcgc 6720 tgttccggcg cgccctgggc ggtgcgtcgt gagcgccctg gaggcactgg ccggacgcct 6780 gcacgtggag gtgcgcctgc aggacggtgt catccgcgcc gtcgataccc gactgcagcg 6840 cccgctgccg cagatttccc gcctgctcgt cgggcagacc gcggaggcgg ccctgaggcg 6900 cctgccgctg ctgttcggcc tgtgcgccgc ggcgcagcag gtggcggcac tacgggcgct 6960 ggagcgggcc gccggctggg cggcgattgc cgaggtggag gagggccgca cccggctcgg 7020 cgaactggag tcgatccgtg agtccctgct gcgcctggtg caggtctggg agctgcctgt 7080 gcccctggag cggctcaagg cgctgctcgc cctgtgccgg cgcgccgccg cccgcctgca 7140 agcgctgacc gcctttcgcg ccgcgccgtt gccggccgat gcggagctgg aggggacgct 7200 ggccgcgctg gccgccgcct gggccgacct gcaaccgccg gcaccggccg actggctgcg 7260 tccgcgtctc gaccgctggc aggaagtcgc gctcggtgga ccgccaccgc aggccttcac 7320 agcggacgaa ttgccggcgc tgctggcgca attgcgcgcc agcgacgcgc gcgccgagat 7380 cgccgggcag ccgcggctcg gcgggccggc cgccagcgcc ggggcgcagg cgacggcgag 7440 cgcgcagatc gagcagcacg tcggcgcgct gctgcggcgc acggcgcagg cgatagactc 7500 gctgcagtcg ccgccagcgc cgccggccgt ggccgggctg gcggcgggag agggtgtcgg 7560 cctggcgcgg accgcccgcg gctggctgct gcaccgggtg tgcctggacg acggggcggt 7620 cggcacctgg caactgctgg cgccgaccga ctggaatttc catgccgacg gcccgctgcg 7680 ccgccggctg tgcggcgtgc gggtggccgc cggggaggtc gaggcgctgc tgcgcgaact 7740 gatcctcgcg ctcgatccct gcgtcgcttt cgaggtgaag atcgtccatg catgaaatgt 7800 cgatcgccga gggcatcgtc cagcttctcg aagagcaggc cgtggcgcag gacttcactc 7860 gggtcagggc gctgtggctg gagatcggcc cgctggccgc gatcgaggtc gagtcgttgc 7920 gcttctgctt cgaggcggtg acccgcggca gcctcgccga aggcgcgcgc ctggagatcg 7980 tcgaactgcc ggggcgcgcc tggtgcctcg gctgcaacgc cagcgtggcg atccgccggc 8040 gctacgatgc ctgcccgcag tgcggcagtc atcgcttgca agtcacccag ggcgacgagc 8100 tgcgggtcaa ggaactggag gtagagtaag catgtgtacc gtttgcggct gcgccgaggg 8160 cgagacccgg atcgagggcg agcaccatca ccacggccac gaccatcatc accacgagca 8220 tcctttcgtg cgccgcccgg cgccggccga ggccgcgccg ccggcggccg gaggcccgaa 8280 cctgcacttc ggccagggcc cggcccgcgc ccatgcgcca ggcctcagcc agagccgcat 8340 gctgcggatc gagcaggaca tcctcggcaa gaacgaccgc tacgccgccg agaaccgcgc 8400 gcgcttcgag gccctgtcgc tgttcgtcct caacctggtg tccagccccg gctcgggcaa 8460 gaccagcctg ctgacccgga ccatcgagct gctcggccgg cgccggccgc tggcggtgat 8520 cgagggcgac cagcagaccg accacgacgc cgcgcgcatc cgtgccaccg gcgtgccggc 8580 ggtgcagatc aacaccggca agggctgcca cctggacgcg cacatggtcg gccacgccct 8640 ggcgcggctg gacgatctcg aaggcggcct gctgttcatc gagaacgtcg gcaatctggt 8700 ctgcccggcg gccttcgatc tgggcgaggc gcacaaggtg gcgatcctct cggtcaccga 8760 gggcgaggac aagccgctca agtacccgga catgttccac gccgccgacc tcatgctgct 8820 gaacaagacc gacctgctgc cgcacctgga tttcgacgtc gaggcctgca tcgcctacgc 8880 ccggcgggtc aacccggaca tcgaggtgat ccgtgtctcg gcgcgcagcg gcgagggcat 8940 gggcgagtgg ctggcctgga tcgagcgtca gcgcggcacc cgcctgcgcg cgcggatcga 9000 cgcgctcagg gaacaggctc gggccctgga ggcgctgctc tgaatcagcc ggcggaagca 9060 ggcgtgcgcc tgctgctgcg cggtcgggtg cagggggtcg gcatgcgtcc ctgcgtgcac 9120 cgtctggcca cctccctcgg cctggccggc gaggtgcgca acaccggcgc gggtgtgcgc 9180 atcgacctgc tgggcccgcc gcaagcgctc gccgaattcg agcgtcgcct gcccgatgaa 9240 ctgccgccgc tggcgcgcct cgacgccatc cagcgcgaac ccctgcccgc cgggacgcgc 9300 tttgccggct tcgccatcgc ggccagccgc gacgagaggc gcggggcgct ggcgccgccg 9360 ccggatgccg cggtctgccc ggcctgtctc gaagaactct tcgatccgca cgaccgccgc 9420 tggcgccatc ccttcatcaa ctgcacccac tgcggcccgc gctacagcct gatccgccgc 9480 ctgccctacg accgcgtcca gaccagcctg gccggcttcg aactctgccc cgagtgccgg 9540 cgcgaatacg aagacccggc cgatcgccgc ttccacgccc agccgatcgc ctgcccggcc 9600 tgcggcccgc ggctctgttg cgaggacgcc agcggccggc gcctgtccgg cgaccccatc 9660 gaacgggccc tggcggccct cgcgcgcggc gaaattctcg ccctgcgcgg ggtcggcggc 9720 ttccatctgg cctgcgatgc gcgcaacgcc ggggcggtgg ccgaactacg ccgacgcaag 9780 cgccgcccgg ccaagccttt cgcgctgatg gccgccaacc cggcctcgct gcaggcgctg 9840 gtcgagttga acgaaaacgg tctcgccgag ctgagcggtc cggccgcgcc ggtggtgctg 9900 ctgcgcaagc gtcccgccgc cgatgacttg ctcgccgccg gggtggcgcc ggatctcgcc 9960 tggctcggcg cgatgctgcc gcacagtccg ctgcactggc tgctgttcca cgaggccgcc 10020 gggcggccgg ccggcacggg ctgggccgcc gcgccccagg atctgctgct ggtgatgacc 10080 agcgccaacc tgagcggcgc gccgccgatc accggcaacg ccgaggcgcg cgagcggctc 10140 gccggcatcg ccgacctctg gctgttgcac gaccgcgaga ttctcaaccg ctgcgacgat 10200 tcggtggtca gtgccctggg ccgcgcgccg ctggtgatcc gcagcggccg tggcctggcg 10260 cccctggaaa tccctctggc ccgcggcggc ccgtcgatac tggccctggg cggccagttg 10320 aagaacgccg tctgtctgac ccggggcgac cgtgcctggc tgtccccgca caacggcgat 10380 ctggacgatg ccgatacctg ccgcgccctg gagcgcacgg tggcacggct cggcgagttg 10440 ctcggcatcc gtcccgagcg cgtcgcctgc gacctgcacc cggatttttt cgccagccgc 10500 ttcgcccgcg actacgccga gcgccacggc ctgccgctgc accccatcca gcaccaccat 10560 gcccacatcg ccgcgacgat ggccgagcac ggcctcgccg agccggtgct cggcctggcg 10620 ctggacggct tcggcctcgg cgccgacggc cggctgcgtg gcggcgagct gctgcgggtg 10680 gcggcggacg gctgcgcctg gctcggcgag ctgaatccgc tgccgctgcc cggcggcgac 10740 caggcatcgc gcgagccctg gcgcatggcc gccggcgccc tgcatgcgct gggccgcggc 10800 ggcgagatcg ccacgcgctt cgccgccgag cccggcaacg cagccattgc gcggatgctc 10860 gaacgcggct tcaattgccc gccgagcagc agcgccggcc ggctgttcga tgccgcggcg 10920 ggcctgctgg gcctgggcgg gcggcagcgt tacgaggccg aggcggcgct gcgcctggag 10980 tcgcgggtgg ttggcctgcc ggagcgggtt cccgcactct ggcggatcga cgacgacaac 11040 cgcctggatc ttttgccgct gctggcgcga ctggccgaca tgcgcgacac gcgggccggc 11100 gccgagctgt tccacggcgt gctgatcgag gccctggcca tctgggcggc gcgtgcggcc 11160 gaggccaccg gtctgcaccg ggttgccctg ggcggcggct gcttcctgaa caccgtgctg 11220 cgcgacggac tctgcgcgcg cctgcgcgcc gccggcctga cgccgctgct ggcgcggcgc 11280 gcgccgctca acgacggcgg tctggccctc ggtcaggcct gggcggtgct gctggcggcg 11340 gacatcccat cgacacgagg acaagcgtga tgtgcctggc cattccggtc cgcatcgagg 11400 aactgctcga cgagcagagt gcggtcgcct gcatcggcgg cctgcgcaag accatcaacg 11460 tcgccctgct cgacgatctg aaagtgggcg actacgtgat cctgcacgtc ggcttcgccc 11520 tgcagaagct cgacgaggcc gaggcgcagc gcaccctggc gctgctcgcc gagttgggcc 11580 gattggccga ggccgagcag gccgcgcagg gagaggcgcc atgaagtacg tcgacgaatt 11640 ccgcgacggc gccaccgcgc gccagctcgc cgcgcgcatc gccgccgagg ccgatccgaa 11700 gcgccagtac cggctgatgg agttctgcgg cgggcacacc cacgcgatct tccgctacgg 11760 catccccgac ctgctgccgg ccaacgtgcg gctgatccac ggccccggct gcccggtctg 11820 cgtgatgccg atcggccgcc tggacatggc catcgaactg gcgcgccgcc ccggcgtgat 11880 cctctgcacc tacggcgaca tgttgcgcgt gcccgcctcc gggcgcgtca gtctgctcaa 11940 ggcgcgcgcc gaaggcgccg cagtgcgcat gctctactcg ccgatcgagg cgctgaagct 12000 ggcccaggac aacccggaca gggacgtggt gttcttcgcc atcggcttcg agaccaccac 12060 gccgcccacc gcgctggtga tcgaacaggc gcagaggctc ggcttgaaga acttctcggt 12120 gttctgcaac cacgtgctga ccccggcggc gatgcacgcc atcctcgcca ccccggaggc 12180 gcgcgccggc acgctgcaac tggacggctt catcggcccg gcccacgtca gcacggtgat 12240 cggcagcgac gcctacgcgc ccttcccgcg tcagtacggc acgccgctgg tgatcgccgg 12300 cttcgaaccg ctggacctgt tgcaggcgct gctgatgctg gtgcgccagc tcaacgaggg 12360 gcgtgccgag gtggaaaacc agttcacccg cgcggtcacc gcaggcggca atctcaaggc 12420 gaaggcgctg accgggcgga tcttcgagct gcgcgagagt ttcgagtggc gcggcctggg 12480 cgcgctgccg aacagcgccc tgcggatccg cgaggccttc gccgaattcg acgccgagcg 12540 gcgcttcgct ctcgaagcgc gcagcggcct ggagaacaag gcctgcgaat gcccggcgat 12600 cctccgcggg gcgaagagcc cgcgcgactg caagctgttc ggcaacccct gcagcccgga 12660 caatccgctc ggctcgtgca tggtttcctc cgagggcgcc tgcgccgcct ggtacgccta 12720 cggccgccag cgccaggccg tcgtggcggt ggcccgatga gccggctcga tctcaggaac 12780 ggcagcgtgg agatggtcca cggcagcggc ggccgcgcca tgggccaact gatcgaggaa 12840 ctgttcgccc gcgctctgcg caacgagtgg ctggaccagc gcaacgatca ggcgcagttc 12900 gagctgccgc ccggccgggt agtgatggcc accgacagcc acgtgatctc gccgctgttc 12960 ttccccggcg gcgacatcgg cagcctcgcc gtgcacggca ccatcaacga cgtggccatg 13020 gccggcgccc gaccctgcta cctggccgcc ggcttcatcc tcgaggaggg ttttccgctc 13080 gccgacctgg cgcgcatcgt cgagtcgatg gccgccgccg cccgcgaggc cggcgtgccg 13140 gtggtcaccg gcgacaccaa ggtggtcgaa cacggcaagg gcgacggggt gttcatcacc 13200 accaccgggg tcggcgtggt gccgccgggc ttgcacctct ccggcgacca ggcgcggccg 13260 ggcgaccgca tcctgctttc cggcagcatc ggcgaccacg gcgtgaccat cctctcgttg 13320 cgcgagggcc tcggcttcga ggccgacatc ggctccgact cccaggccct gcacggcctg 13380 gtcgccgcca tgctcgcggc ggtgccggag atccgctgcc tgcgcgaccc gacccgcggc 13440 ggcctgggca acaccctcaa cgaactggcc cgccagtcgg gggtcggcat gcaactcgtc 13500 gagcgggcca tcccggtgcg cgaaccggtg cgtgccgcct gcgaattcct cggcctcgac 13560 ccgctgtacg tggccaacga aggcaagctg atcgccatct gcccggccga gcgggccgag 13620 cgcctgctcg aagcgatgcg tgcgcatccg caggggcgcg aggcggcgat catcggcacg 13680 gtggtggccg acgagcaccg tttcgtgcag atggagacac cgttcggtgg gagtcggatg 13740 gtggactggt tgagcgggga gcagttgccg aggatttgct gacaaggtgg acgtttgcac 13800 gacctttgat gtaaaccggt gcatttcctc ggcacgaccc acaggtttca ccctgcacgg 13860 cgacttactt ttgtcagtcg cacctgcccg gccggggcaa aagtaagcaa aaac 13914 // |
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