EBI Dbfetch

ID   L20679; SV 1; linear; mRNA; STD; VRT; 1651 BP.
XX
AC   L20679;
XX
DT   29-JAN-1994 (Rel. 38, Created)
DT   17-APR-2005 (Rel. 83, Last updated, Version 6)
XX
DE   Xenopus laevis tryptophan hydroxylase mRNA, complete cds.
XX
KW   tryptophan hydroxylase.
XX
OS   Xenopus laevis (African clawed frog)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Xenopus.
XX
RN   [1]
RP   1-1651
RX   PUBMED; 8189245.
RA   Green C.B., Besharse J.C.;
RT   "Tryptophan hydroxylase expression is regulated by a circadian clock in
RT   Xenopus laevis retina";
RL   J. Neurochem. 62(6):2420-2428(1994).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1651
FT                   /organism="Xenopus laevis"
FT                   /mol_type="mRNA"
FT                   /dev_stage="Adult"
FT                   /tissue_lib="lambda ZAPII 'dark'"
FT                   /tissue_type="Retina"
FT                   /db_xref="taxon:8355"
FT   5'UTR           1..11
FT   CDS             12..1457
FT                   /codon_start=1
FT                   /product="tryptophan hydroxylase"
FT                   /EC_number="1.14.16.4"
FT                   /note="The methionine codon at base 12 is a putative
FT                   initiation codon. The real initiation codon could be
FT                   upstream of this position and not present in our cDNA"
FT                   /db_xref="GOA:Q92142"
FT                   /db_xref="HSSP:1MLW"
FT                   /db_xref="InterPro:IPR019773"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q92142"
FT                   /protein_id="AAA21306.1"
FT                   /translation="MYSNRKECPRRVKSFDSVNSGLDENQINNEFNKSTYIKIEDNKEY
FT                   SENVCERGKASVIFSLKNEIGGLVKALKLFQEKHVNLIHIESRKSKRRNSEFEIFVDCD
FT                   SNREQLNEIFQLLKPHVNVISMSPPENFTVQEDDMESVPWFPKKISDLDKCANRVLMYG
FT                   SDLDADHPGFKDNVYRKRRKYFADVAMSYKYGDPIPHIEFTEEEIQTWGTVFRELNKLY
FT                   PTHACREYLKNLPLLSKHCGYREDNIPQLEDVSRFLRERTGFTIRPVAGYLSPRDFLAG
FT                   LAFRVFHCTQYVRHDSDPLNTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDE
FT                   AVQKLATCYFFTVEFGLCKQEGKLKVYGAGLLSSISELKHSLSGNAKVKPFDPMVTCNQ
FT                   ECIITSFQELYFVSESFEEAKEKMREFAKTIQRPFGLKYNPFTQSVDILKDTKSIAMVV
FT                   RELRHELDIVNDALNKMNKQLGV"
FT   3'UTR           1455..1651
FT                   /note="'The clone has about 2 Kb of 3'UT seq., including a
FT                   polyA tail and is extremely repetitive. The 3' end was not
FT                   sequenced"
XX
SQ   Sequence 1651 BP; 479 A; 382 C; 391 G; 399 T; 0 other;
     ggcacgagca aatgtattcc aaccgcaagg agtgcccccg cagggtcaag tcctttgatt        60
     cagtcaactc tggattggat gagaatcaga tcaataatga gttcaataaa tcaacttaca       120
     tcaagatcga agacaataaa gaatacagtg agaatgtgtg cgagagaggg aaggcctcag       180
     tcatcttctc cctaaagaat gagattgggg ggctggtcaa agcactgaag cttttccagg       240
     agaaacacgt caatctcatt catattgagt cccgaaagtc aaagagaaga aactctgagt       300
     ttgagatctt tgtggattgt gacagcaaca gggaacaact gaatgaaatc ttccagctgc       360
     tcaagcctca cgtcaatgtg atatccatga gcccccctga gaacttcact gtgcaggagg       420
     acgatatgga aagtgtcccc tggttcccca agaagatctc tgacctggac aaatgcgcaa       480
     acagagttct aatgtacgga tcagatctgg acgccgacca ccctggtttc aaggacaatg       540
     tgtaccgtaa gagacgcaag tattttgccg acgttgcaat gtcctacaaa tatggggatc       600
     caatacccca cattgagttt acagaagagg agatacagac ctgggggaca gttttccggg       660
     agctcaataa gctgtaccca acacacgcct gccgagagta cctaaagaac ctgccactct       720
     tgtccaaaca ctgcgggtac agagaagata atatccccca actggaagat gtgtctcgat       780
     ttctccgaga gcgcacagga ttcaccattc gtcccgtcgc tggatatttg tctcccagag       840
     atttccttgc aggactggcc ttccgggttt ttcactgcac ccaatatgtg aggcacgact       900
     ccgacccact taatacccct gagccggaca cttgccatga acttctggga catgttcctc       960
     ttcttgccga acccagtttt gcccagttct cccaagaaat tggcttggcc tccttggggg      1020
     catccgatga agctgtacaa aaactggcta cctgctactt cttcacagtt gagtttggat      1080
     tgtgcaaaca agaaggaaaa ctgaaggtat atggggccgg actgctttct tctatcagtg      1140
     agctgaagca ctctctctct ggaaatgcca aagtgaagcc ttttgacccc atggtaacct      1200
     gcaaccagga gtgcatcatc acttcattcc aggagcttta ctttgtctcg gagagttttg      1260
     aagaagccaa agagaagatg agagaatttg ctaaaaccat tcaacgcccc tttgggctga      1320
     agtacaatcc ctttacccag agcgtggata tcctaaagga tacaaagagc atcgccatgg      1380
     tggtcagaga gttgcgtcat gaactggaca ttgtcaacga tgcacttaac aagatgaaca      1440
     agcagcttgg ggtttaaggg ggagctttaa aactggtgga gaggaaacaa tgcggcttca      1500
     atatgtcagt gtaaagccac atttgataat ctctgcaaat aatcacaggg cccaggatgc      1560
     ttggtagcac tggatcgttc catagagttg cagagcttta tttttgtaac agggaaatat      1620
     atattatata tagtacagcc cattagggaa a                                     1651
//