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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   L10325; SV 1; linear; mRNA; STD; MAM; 1510 BP.
XX
AC   L10325;
XX
DT   06-FEB-1993 (Rel. 34, Created)
DT   17-APR-2005 (Rel. 83, Last updated, Version 5)
XX
DE   Cow glutathione peroxidase (GPx) plasma isoform mRNA, complete cds.
XX
KW   detoxification; glutathione; glutathione peroxidase; peroxidase;
KW   plasma protein; secreted protein; selenium; selenocysteine; selenoprotein;
KW   xenobiotic.
XX
OS   Bos taurus (cattle)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
XX
RN   [1]
RP   1-1510
RX   PUBMED; 8262911.
RA   Martin-Alonso J.M., Ghosh S., Coca-Prados M.;
RT   "Cloning of the bovine plasma selenium-dependent glutathione peroxidase
RT   (GP) cDNA from the ocular ciliary epithelium: expression of the plasma and
RT   cellular forms within the mammalian eye";
RL   J. Biochem. 114(2):284-291(1993).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1510
FT                   /organism="Bos taurus"
FT                   /mol_type="mRNA"
FT                   /dev_stage="newborn"
FT                   /clone_lib="Lambda gt11"
FT                   /tissue_type="ocular ciliary epithelium"
FT                   /db_xref="taxon:9913"
FT   sig_peptide     12..68
FT                   /gene="GPx"
FT                   /note="putative"
FT   CDS             12..692
FT                   /codon_start=1
FT                   /transl_except=(pos:228..230,aa:OTHER)
FT                   /gene="GPx"
FT                   /product="glutathione peroxidase"
FT                   /EC_number="1.11.1.9"
FT                   /note="plasma isoform; putative; selenocysteine"
FT                   /db_xref="GOA:P37141"
FT                   /db_xref="InterPro:IPR000889"
FT                   /db_xref="InterPro:IPR012335"
FT                   /db_xref="InterPro:IPR012336"
FT                   /db_xref="UniProtKB/Swiss-Prot:P37141"
FT                   /protein_id="AAA16579.2"
FT                   /translation="MARLFRASCLLSLLLAGFIPPSQGQEKSKTDCHAGVGGTIYEYGA
FT                   LTIDGEEYIPFKQYAGKYILFVNVASYXGLTGQYVELNALQEELEPFGLVILGFPCNQF
FT                   GKQEPGENSEILATLKYVRPGGGFTPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELL
FT                   GSPDRLFWEPMKVHDIRWNFEKFLVGPDGIPIMRWYHRTTVNSVKMDILTYMRRRAVWE
FT                   AKGK"
FT   polyA_signal    1490..1495
FT                   /gene="GPx"
FT                   /note="putative"
FT   polyA_site      1510
FT                   /gene="GPx"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
XX
SQ   Sequence 1510 BP; 321 A; 498 C; 383 G; 308 T; 0 other;
     cccaccccgc catggcccgg ctcttccggg catcctgcct tctgtccctg ctcctggccg        60
     gcttcattcc cccgagccag ggacaggaga agtcgaagac ggactgccac gctggtgtgg       120
     gtggcaccat ctatgagtac ggggccctca ccatcgatgg ggaggagtac atccccttta       180
     agcagtacgc tggcaaatac atcctcttcg tcaacgtggc cagctactga ggcctgacgg       240
     gccagtacgt tgaactgaat gcactgcagg aagagcttga accatttggt ctggtcattc       300
     tgggcttccc ctgcaaccaa tttggaaaac aagaaccagg agagaactcg gagatcctag       360
     ccaccctcaa gtatgttcga ccaggtgggg gcttcacccc caatttccaa ctgtttgaga       420
     aaggcgatgt gaatggggag aaagagcaga agttctacac gttcctgaag aactcctgtc       480
     ctcctacctc ggagctccta ggctcacctg accgcctttt ctgggaaccc atgaaggtcc       540
     atgacatccg gtggaacttt gagaagttcc tggtggggcc agacggcatc cccatcatgc       600
     gctggtacca ccgcaccacg gtcaactctg tcaagatgga catcctgacc tacatgcggc       660
     ggcgggcggt ctgggaggcc aaggggaagt aactgaggcc caccgcccct ccccccaagt       720
     ccaccacacg ggctagggag gactctgttc aggaaggaac ccatttctcc aactacacca       780
     cactcccatg ctagaccctt tactgttaca caaggcccca gcctgagatg aacgtttgtg       840
     cccgtactgc tctgcacatg ggcgtttgca cacatgccta caggctgtgt acacacgagt       900
     acagggccac atgtgtcaac ctgcacaagt gtatatgtgg caacagctgt gtgccatgaa       960
     gaatgccaga gaggaacttc cctttccttc cagttctctg ttccagtgat aaccatccac      1020
     tttcagctga gtccaaactg aaaaaccagc tctagattca attgttctgc tttaaccagg      1080
     acctcaccct accggctggc atctcttact gcctccaaac accacccaga agtgcctgga      1140
     agtttctggg tccgccacac tgcctgaccc cctccttctc caccacacag cctcgctcct      1200
     tcctgagggc cctcccctgc cccccacccc accaccccca cagcgttccc tgagagtcgc      1260
     caaggcagat gtgagagcag gggccacgtt ccccatgtga gggggcggca tcgccatgaa      1320
     ggaggggccc gaagcccgcg tgggcgggcc tcccttgagc ctgtctgagg ggccagcctt      1380
     tagtgcattc aggctgaggc cccggccagg gatgccaccc cactccctcg gggggtgtgt      1440
     cctctcccct caccctgacc cactggcatg aaactcaccc ctgtctgcct agtaaaggcc      1500
     tttctgcagc                                                             1510
//
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