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EBI DbfetchID L09232; SV 1; linear; genomic DNA; STD; PRO; 4705 BP. XX AC L09232; XX DT 16-SEP-1993 (Rel. 37, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 6) XX DE Corynebacterium glutamicum acetohydroxy acid synthase (ilvB) and (ilvN) DE genes, and acetohydroxy acid isomeroreductase (ilvC) gene, complete cds. XX KW acetohydroxy acid isomeroreductase; acetohydroxy acid synthase. XX OS Corynebacterium glutamicum OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Corynebacteriaceae; Corynebacterium. XX RN [1] RP 1-4705 RX PUBMED; 8366043. RA Keilhauer C., Eggeling L., Sahm H.; RT "Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of RT the ilvB-ilvN-ilvC operon"; RL J. Bacteriol. 175(17):5595-5603(1993). XX CC On Oct 2, 1994 this sequence version replaced gi:400332. XX FH Key Location/Qualifiers FH FT source 1..4705 FT /organism="Corynebacterium glutamicum" FT /mol_type="genomic DNA" FT /tissue_lib="ATCC 13032" FT /db_xref="taxon:1718" FT CDS complement(<1..187) FT /codon_start=1 FT /transl_table=11 FT /note="ORF X'" FT /db_xref="GOA:P42531" FT /db_xref="InterPro:IPR006685" FT /db_xref="UniProtKB/Swiss-Prot:P42531" FT /protein_id="AAA62428.1" FT /translation="MRIIKRRVESAADADTTKNQLAFAGVGVYIAQIVAFFMLAVSAMQ FT AFGFSLAGAAIPATIAS" FT RBS 733..738 FT /gene="ilvB" FT CDS 749..2629 FT /codon_start=1 FT /transl_table=11 FT /gene="ilvB" FT /product="acetohydroxy acid synthase, large subunit" FT /note="amino acid binding site for thiamine pyrophosphate FT at aa positions 466 .. 494" FT /db_xref="GOA:P42463" FT /db_xref="HSSP:1N0H" FT /db_xref="InterPro:IPR012000" FT /db_xref="UniProtKB/Swiss-Prot:P42463" FT /protein_id="AAA62429.1" FT /translation="MNVAASQQPTPATVASRGRSAAPERMTGAKAIVRSLEELNADIVF FT GIPGGAVLPVYDPLYSSTKVRHVLVRHEQGAGHAATGYAQVTGRVGVCIATSGPGATNL FT VTPIADANLDSVPMVAITGQVGSGLLGTDAFQEADIRGITMPVTKHNFMVTNPNDIPQA FT LAEAFHLAITGRPGPVLVDIPKDVQNAELDFVWPPKIDLPGYRPVSTPHARQIEQAVKL FT IGEAKKPVLYVGGGVIKADAHEELRAFAEYTGIPVVTTLMALGTFPESHELHMGMPGMH FT GTVSAVGALQRSDLLIAIGSRFDDRVTGDVDTFAPDAKIIHADIDPAEIGKIKQVEVPI FT VGDAREVLARLLETTKASKAETEDISEWVDYLKGLKARFPRGYDEQPGDLLAPQFVIET FT LSKEVGPDAIYCAGVGQHQMWAAQFVDFEKPRTWLNSGGLGTMGYAVPAALGAKAGAPD FT KEVWAIDGDGCFQMTNQELTTAAVEGFPIKIALINNGNLGMVRQWQTLFYEGRYSNTKL FT RNQGEYMPDFVTLSEGLGCVAIRVTKAEEVLPAIQKAREINDRPVVIDFIVGEDAQVWP FT MVSAGSSNSDIQYALGLRPFFDGDESAAEDPADIHEAVSDIDAAVESTEA" FT RBS 2628..2633 FT /gene="ilvN" FT CDS 2643..3161 FT /codon_start=1 FT /transl_table=11 FT /gene="ilvN" FT /product="acetohydroxy acid synthase, small subunit" FT /db_xref="GOA:Q79VG4" FT /db_xref="InterPro:IPR019455" FT /db_xref="UniProtKB/TrEMBL:Q79VG4" FT /protein_id="AAA62430.1" FT /translation="MANSDVTRHILSVLVQDVDGIISRVSGMFTRRAFNLVSLVSAKTE FT THGINRITVVVDADELNIEQITKQLNKLIPVLKVVRLDEETTIARAIMLVKVSADSTNR FT PQIVDAANIFRARVVDVAPDSVVIESTGTPGKLRALLDVMEPFGIRELIQSGQIALNRG FT PKTMAPAKI" FT RBS 3322..3330 FT /gene="ilvC" FT CDS 3342..4358 FT /codon_start=1 FT /transl_table=11 FT /gene="ilvC" FT /product="acetohydroxy acid isomeroreductase" FT /note="amino acid binding site for NAD (P) at aa positions FT 20-51" FT /db_xref="GOA:Q57179" FT /db_xref="HSSP:1NP3" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:Q57179" FT /protein_id="AAA62431.1" FT /translation="MAIELLYDADADLSLIQGRKVAIVGYGSQGHAHSQNLRDSGVEVV FT IGLREGSKSAEKAKEAGFEVKTTAEAAAWADVIMLLAPDTSQAEIFTNDIEPNLNAGDA FT LLFGHGLNIHFDLIKPADDIIVGMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGTAQ FT ALTLSYAAAIGGARAGVIPTTFEAETVTDLFGEQAVLCGGTEELVKVGFEVLTEAGYEP FT EMAYFEVLHELKLIVDLMFEGGISNMNYSVSDTAEFGGYLSGPRVIDADTKSRMKDILT FT DIQDGTFTKRLIANVENGNTELEGLRASYNNHPIEETGAKLRDLMSWVKVDARAETA" FT terminator 4394..4428 XX SQ Sequence 4705 BP; 1105 A; 1358 C; 1245 G; 997 T; 0 other; ctgacgcaat ggttgccgga atcgcagcgc ccgcgagaga gaaaccaaaa gcctgcatcg 60 cggagacggc aagcatgaaa aacgccacaa tttgcgcgat ataaacgcca acgccggcga 120 acgcgagctg gttcttagtg gtgtccgcat cggctgcaga ctccactcgg cgcttgataa 180 tacgcatggc cagtcggcga tacgtggaat caaaaacgcc aagaccagga taattgctac 240 atcaaaaccg gtatcgacaa tccaattcca caatgaatag agcaaatatt gaatgggtac 300 gcctaaaatc atgagccaag attagcgctg aaaagtagcg ggagcctgcc tgaactttgt 360 gagaatcctg attccttaac cgaagtgggg gagttttggg ggtgggaatt ttcgtgcgtt 420 gtggaattgg aaactcgatg tgtgtagcat gacacaccat gaccattatt cgacttgtag 480 tagtaaccgc gcggcgcctg ccgtaacggc cttccaagtc gtctcgtcaa gcgccctcga 540 caacactcac cacagtgttg gaacgagggc tttcttgttg gttatgaccc aagtagccaa 600 ctttgcaaca gacatctgtc gcactgcgtg cacagcatcc gcgtcggaac aattttaaat 660 gagggctttg tctttaggct gagttgaaat cggcttggct tggacgggtc ctgtgaaaat 720 ccttatttag taaaggagcc agaaagtcgt gaatgtggca gcttctcaac agcccactcc 780 cgccacggtt gcaagccgtg gtcgatccgc cgcccctgag cggatgacag gtgcaaaggc 840 aattgttcga tcgctcgagg agcttaacgc cgacatcgtg ttcggtattc ctggtggtgc 900 ggtgctaccg gtgtatgacc cgctctattc ctccacaaag gtgcgccacg tcttggtgcg 960 ccacgagcag ggcgcaggcc acgcagcaac cggctacgcg caggttactg gacgcgttgg 1020 cgtctgcatt gcaacctctg gcccaggagc aaccaacttg gttaccccaa tcgctgatgc 1080 aaacttggac tccgttccca tggttgccat caccggccag gtcggaagtg gcctgctggg 1140 taccgacgct ttccaggaag ccgatatccg cggcatcacc atgccagtga ccaagcacaa 1200 cttcatggtc accaacccta acgacattcc acaggcattg gctgaggcat tccacctcgc 1260 gattactggt cgccctggcc ctgttctggt ggatattcct aaggatgtcc agaacgctga 1320 attggatttc gtctggccac caaagatcga cctgccaggc taccgcccag tttcaacacc 1380 acatgctcgc cagatcgagc aggcagtcaa gctgatcggt gaggccaaga agcccgtcct 1440 ttacgttggt ggtggcgtaa tcaaggctga cgcacacgaa gagcttcgtg cgttcgctga 1500 gtacaccggc atcccagttg tcaccacctt gatggctttg ggtactttcc cagagtctca 1560 cgagctgcac atgggtatgc caggcatgca tggcactgtg tccgctgttg gtgcactgca 1620 gcgcagcgac ctgctgattg ctatcggctc ccgctttgat gaccgcgtca ccggtgacgt 1680 tgacaccttc gcgcctgacg ccaagatcat tcacgccgac attgatcctg ccgaaatcgg 1740 caagatcaag caggttgagg ttccaatcgt gggcgatgcc cgcgaagttc ttgctcgtct 1800 gctggaaacc accaaggcaa gcaaggcaga gaccgaggac atctccgagt gggttgacta 1860 cctcaagggc ctcaaggcac gtttcccgcg tggctacgac gagcagccag gcgatctgct 1920 ggcaccacag tttgtcattg aaaccctgtc caaggaagtt ggccccgacg caatttactg 1980 cgccggcgtt ggccagcacc aaatgtgggc agctcagttc gttgactttg aaaagccacg 2040 cacctggctc aactccggtg gactgggcac catgggctac gcagttcctg cggcccttgg 2100 agcaaaggct ggcgcacctg acaaggaagt ctgggctatc gacggcgacg gctgtttcca 2160 gatgaccaac caggaactca ccaccgccgc agttgaaggt ttccccatta agatcgcact 2220 aatcaacaac ggaaacctgg gcatggttcg ccaatggcag accctattct atgaaggacg 2280 gtactcaaat actaaacttc gtaaccaggg cgagtacatg cccgactttg ttaccctttc 2340 tgagggactt ggctgtgttg ccatccgcgt caccaaagcg gaggaagtac tgccagccat 2400 ccaaaaggct cgagagatca acgaccgccc agtagtcatc gacttcatcg tcggtgaaga 2460 cgcacaggta tggccaatgg tgtctgctgg atcatccaac tccgatatcc agtacgcact 2520 cggattgcgc ccattctttg atggtgatga atctgcagca gaagatcctg ccgacattca 2580 cgaagccgtc agcgacattg atgccgccgt tgaatcgacc gaggcataag gagagaccca 2640 agatggctaa ttctgacgtc acccgccaca tcctgtccgt actcgttcag gacgtagacg 2700 gaatcatttc ccgcgtatca ggtatgttca cccgacgcgc attcaacctc gtgtccctcg 2760 tgtctgcaaa gaccgaaaca cacggcatca accgcatcac ggttgttgtc gacgccgacg 2820 agctcaacat tgagcagatc accaagcagc tcaacaagct gatccccgtg ctcaaagtcg 2880 tgcgacttga tgaagagacc actatcgccc gcgcaatcat gctggttaag gtctctgcgg 2940 acagcaccaa ccgtccgcag atcgtcgacg ccgcgaacat cttccgcgcc cgagtcgtcg 3000 acgtggctcc agactctgtg gttattgaat ccacaggcac cccaggcaag ctccgcgcac 3060 tgcttgacgt gatggaacca ttcggaatcc gcgaactgat ccaatccgga cagattgcac 3120 tcaaccgcgg tccgaagacc atggctccgg ccaagatcta aacagcaatt aatctgattg 3180 cacctgctgc ataaatgtga ctagtcaaac accgtctaat tacatgtgtg tggtagaaca 3240 ataatgtagt tgtctgccca agcgagttaa actcccacga tttacagtgg ggggcagaca 3300 tcttttcacc aaaattttta cgaaaggcga gattttctcc catggctatt gaactgcttt 3360 atgatgctga cgctgacctc tccttgatcc agggccgtaa ggttgccatc gttggctacg 3420 gctcccaggg ccacgcacac tcccagaacc tccgcgattc tggcgttgag gttgtcattg 3480 gtctgcgcga gggctccaag tccgcagaga aggcaaagga agcaggcttc gaggtcaaga 3540 ccaccgctga ggctgcagct tgggctgacg tcatcatgct cctggctcca gacacctccc 3600 aggcagaaat cttcaccaac gacatcgagc caaacctgaa cgcaggcgac gcactgctgt 3660 tcggccacgg cctgaacatt cacttcgacc tgatcaagcc agctgacgac atcatcgttg 3720 gcatggttgc gccaaagggc ccaggccact tggttcgccg tcagttcgtt gatggcaagg 3780 gtgttccttg cctcatcgca gtcgaccagg acccaaccgg aaccgcacag gctctgaccc 3840 tgtcctacgc agcagcaatc ggtggcgcac gcgcaggcgt tatcccaacc accttcgaag 3900 ctgagaccgt caccgacctc ttcggcgagc aggctgttct ctgcggtggc accgaggaac 3960 tggtcaaggt tggcttcgag gttctcaccg aagctggcta cgagccagag atggcatact 4020 tcgaggttct tcacgagctc aagctcatcg ttgacctcat gttcgaaggt ggcatcagca 4080 acatgaacta ctctgtttct gacaccgctg agttcggtgg ctacctctcc ggcccacgcg 4140 tcatcgatgc agacaccaag tcccgcatga aggacatcct gaccgatatc caggacggca 4200 ccttcaccaa gcgcctcatc gcaaacgttg agaacggcaa caccgagctt gagggccttc 4260 gtgcttccta caacaaccac ccaatcgagg agaccggcgc taagctccgc gacctcatga 4320 gctgggtcaa ggttgacgct cgcgcagaaa ccgcttaagt ttcacccctt tgacggctta 4380 accgccgcat aggaaatgcc ctccggacta attgtctgga gggcattttt gctacctgct 4440 gtgcactttg tacataaggc aacaagattt tggcaaaatg gtggccaaaa tgaggaaatc 4500 cttggtgccg aaagtacgcg cggaagaaaa aggccaccct tttcaaaggg cggcctttaa 4560 aagacgtgtt agaaactagt gctccagcag atgcagcatc cgcttacgca gggctgtggt 4620 ctcggcttca acagaagcgt cttcactcag ctcgtgtctg gggcggggaa gattcactgg 4680 aatatcggtg atgatggtgg cttcg 4705 // |
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