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EBI DbfetchID J03375; SV 1; linear; genomic DNA; STD; PRO; 6080 BP. XX AC J03375; XX DT 20-FEB-1989 (Rel. 18, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 5) XX DE M.fervidus methyl coenzyme M reductase component C genes mcrA, mcrB, mcrC, DE mcrD, and mcrG, complete cds. XX KW methyl coenzyme M reductase. XX OS Methanothermus fervidus OC Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; OC Methanothermaceae; Methanothermus. XX RN [1] RP 1-6080 RX PUBMED; 3170483. RA Weil C.F., Cram D.S., Sherf B.A., Reeve J.N.; RT "Structure and comparative analysis of the genes encoding component C of RT methyl coenzyme M reductase in the extremely thermophilic archaebacterium RT Methanothermus fervidus"; RL J. Bacteriol. 170(10):4718-4726(1988). XX CC Printed copy of sequence for [1] kindly provided by J.W.Brown, CC 18-AUG-1988. XX FH Key Location/Qualifiers FH FT source 1..6080 FT /organism="Methanothermus fervidus" FT /mol_type="genomic DNA" FT /db_xref="taxon:2180" FT gene 189..1505 FT /gene="mcrB" FT CDS 189..1505 FT /codon_start=1 FT /transl_table=11 FT /gene="mcrB" FT /note="methyl coenzyme M reductase beta subunit" FT /db_xref="GOA:P12972" FT /db_xref="HSSP:1HBN" FT /db_xref="InterPro:IPR003179" FT /db_xref="UniProtKB/Swiss-Prot:P12972" FT /protein_id="AAA72193.1" FT /translation="MPKYEDKVDLYDDRGNLVEEQVPIEALSPLRNTAIKKIIHDIKRT FT VAVNLEGIENALRSAKVGGSGCHIPGRELDVDVIDNAEAIAEKAKEMIQVEEGDDTVVE FT LLHDGKRALVKVPSSRLESAAEYSVAPLVTASAFIQSIIDVCDISIYDANMVKAAVLGR FT YPQSVEYVGGNIATMLDIPQKLEGPGYALRNILVNHIVAATLKNTLQAVALSSILEHTA FT MFEMGDAVGKFERLHLLGLAYQGLNADNLLYDLVKANGKDGTVGSVVEDVVERAKEDGV FT IKVEKELNGYKVYGTDDLALWNAYAAAGLVAATIVNQGAARAAQGVSSTILYDNDIIEF FT ERGLPGVDFGRAEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMAL FT DAGTQMFSPELTSGLIKDVFSKVDEFREPLKYVVELQPK" FT gene 1548..1943 FT /gene="mcrD" FT CDS 1548..1943 FT /codon_start=1 FT /transl_table=11 FT /gene="mcrD" FT /note="methyl coenzyme M reductase delta subunit" FT /db_xref="GOA:P12974" FT /db_xref="InterPro:IPR003901" FT /db_xref="UniProtKB/Swiss-Prot:P12974" FT /protein_id="AAA72194.1" FT /translation="MDVEIFPHRLLSAETTEKLLNKLGEIEGIKRMIIQGQRLPAGEHP FT DRRVINVKGQDIELKVKTGRIFVEIEDKKTMEKIKEVCDEVFPFKYELIPGTFFRRQKT FT VTDAIKFGKDVDKLPTELVGMTDTVLD" FT gene 1994..2608 FT /gene="mcrC" FT CDS 1994..2608 FT /codon_start=1 FT /transl_table=11 FT /gene="mcrC" FT /note="pot. methyl coenzyme M reductase subunit a; FT putative" FT /db_xref="GOA:Q49175" FT /db_xref="InterPro:IPR007687" FT /db_xref="UniProtKB/TrEMBL:Q49175" FT /protein_id="AAA72195.1" FT /translation="MIGRTTHIVDCRETMGLGEGGGLAQRGTFAQCGGDVVAVAMSPGR FT RHITKPICEITFALRENDIKVSTLVLNAGAGVPSDAPEAGAGGLFGITPEEAEQIGRHK FT LALVHLGAVRYHIIYKARLILRNVSMVPCIIVCEYPVDFEDFAKIGVKTRAVMPDKPQT FT KGIVVDIVSGVVRGETCPQEKLDEIVNKVKKWLNVLTRLEY" FT gene 2627..3376 FT /gene="mcrG" FT CDS 2627..3376 FT /codon_start=1 FT /transl_table=11 FT /gene="mcrG" FT /note="methyl coenzyme M reductase gamma subunit" FT /db_xref="GOA:P12973" FT /db_xref="HSSP:1HBN" FT /db_xref="InterPro:IPR003178" FT /db_xref="UniProtKB/Swiss-Prot:P12973" FT /protein_id="AAA72196.1" FT /translation="MAQFYPGSTKIAENRRKFMNPDAELEKLREISDEDVVRILGHRAP FT GEEYPSVHPPLEELDEPEDPIKDIVEPTEGAKAGDRVRYVQFTDSVYFAPAQPYIRSRA FT YLWRYRGADAGTLSGRQIIEARERDVEKIAKELIETEFFDPARTGIRGKSVHGHSLRLD FT ENGMMFDMLRRQVYDEETGRVKMVKNQIGDEFDEPIDLGEPLDEETLKEKTTIYRIDNI FT PYREDKDLLEIVQRIHQLRSEAGFSPE" FT gene 3394..5061 FT /gene="mcrA" FT CDS 3394..5061 FT /codon_start=1 FT /transl_table=11 FT /gene="mcrA" FT /note="methyl coenzyme M reductase alpha subunit" FT /db_xref="GOA:P12971" FT /db_xref="HSSP:1HBN" FT /db_xref="InterPro:IPR015823" FT /db_xref="UniProtKB/Swiss-Prot:P12971" FT /protein_id="AAA72197.1" FT /translation="MAEERKKLFVDALRKKFKEEPKERKTTFYTLGGWKQSERKKEFVE FT YGKKVAKERGIPAYNPDIGTPLGQRVLMPYQVSTTDTFVEGDDLHFVNNLAMQQFWDDI FT RRTVIVGLNHAHRILERSLGKEVTPETINHYLETVNHAMPGAAVVQEHMVETHPGLTAD FT SYVKVFTGNDELADEIESCYLIDINKQFPEHQAEQLKKAIGHTIWQAVRIPTIVSRTCD FT GATTSRWSAMQIGMSMISAYKQAAGEAATADFAYAAKHAEVIHLGTFLPVRRARGENEL FT GGVPFGFLADIVQSSRVHYEDPVRVALDVVASGAMLYDQIWLGSYMSGGVGFTQYATAS FT YTDNILDDFTYYGKEYVEDKYGGLAEAPHDFDTILDVATEVTLYSLDQYEEYPTLMEDH FT FGGSQRAAIAAAASGCSTAFAAGNAQAGLSGWYLSQILHKECHARLGFYGYDLQDQCGA FT ANTYSIRSDEGLPAELRGPNYPNYAMNVGHLGEYAGIVQAAHIARGDADSLNPLVKVAF FT ADDNLPFDWTNPRGEFAKGALREFEPEGERDLIRPAGK" FT CDS 5174..5947 FT /codon_start=1 FT /transl_table=11 FT /note="ORF258, pot. methyl coenzyme M reductase subunit a'; FT putative" FT /db_xref="GOA:Q49176" FT /db_xref="InterPro:IPR005780" FT /db_xref="UniProtKB/Swiss-Prot:Q49176" FT /protein_id="AAA72198.1" FT /translation="MDPAVASLGILALTTASAIIGQTIEDVETNIGSQSNPNSQVQLAP FT QMGNLHRFFNKAIAGEPFAYCTFCGVSGAITVATLYLHLPAVIALAIGAAITTLIWLAY FT STTAYLGRVSGSATFNQPVFLDMLTENLGPIAGHAFIVFFCMTGVAYLMTLPVKGFAHP FT FPIPVIGMIWGMTIGAIGSAVGDVYYGAEAEFVHKKFGGGIPVASHGDITRKGVLGARS FT PMEVGNFTVKYGSPITGMAFGLIVLSITRGVYNIE" XX SQ Sequence 6080 BP; 2203 A; 881 C; 1334 G; 1662 T; 0 other; ttttcacttt atgtagttgt aataatacta ttgaaataaa aaatatgaga cagttttagg 60 agtaactcta atatataatc atttttctgc acttatatat ttttctactt gactgtaaaa 120 gaaaatttca ttaaatatgt aatttataca attattcaca aaaagatatt taaaaaggag 180 gttaattaat gccaaaatat gaagataaag tagatttgta tgatgatagg ggcaacttag 240 ttgaagaaca agtacctatt gaggctttaa gtccattgcg aaatacagca ataaagaaaa 300 ttatacatga catcaaaaga acagttgctg taaatttaga aggaattgaa aatgcattaa 360 gaagcgcaaa agttggaggt tctggttgtc acatacctgg tagagaactt gatgttgatg 420 tcatagataa tgctgaagca attgctgaaa aagccaaaga aatgattcaa gtggaagagg 480 gcgatgatac agttgtagag ttactacatg atggtaaaag agctttagtt aaagtacctt 540 catcaagatt agaatctgct gctgaatact ctgttgcacc tcttgttaca gcatcagcat 600 ttatacaatc aataattgat gtatgtgaca ttagcatcta tgatgcaaac atggttaaag 660 ctgctgtatt gggaagatat ccacaatctg tagaatacgt cggtggaaac attgctacaa 720 tgttagatat acctcaaaaa ttagaaggac ctggatacgc attaagaaac attttagtta 780 atcacatagt agcagcaaca cttaaaaata cattgcaggc tgtagcttta tcttcaattc 840 tagaacatac ggcaatgttt gaaatgggag acgctgttgg aaaatttgaa agattgcatt 900 tacttggtct agcatatcag ggcttaaacg ctgataattt gttatatgat ttagttaaag 960 ctaatggaaa ggatggaaca gttggatcag ttgttgagga cgttgttgaa agagcaaaag 1020 aagatggtgt aataaaagtt gaaaaagaat taaatggata taaggtatat ggtacagatg 1080 atttggcatt atggaatgca tatgctgcag ctggattagt agcagctaca attgttaatc 1140 aaggagctgc aagagcggct caaggtgtat cgtcaacaat tctttacgac aatgacatta 1200 ttgaatttga aaggggcctg cctggcgttg attttggaag ggcagaaggt acagctgtag 1260 gtttctcatt cttcagtcac tcaatctatg gtggtggagg acctggaata tttaatggaa 1320 accacattgt gacaaggcat agtaaaggat ttgcaattcc ttgtgttgcc gctgcaatgg 1380 cattagatgc tggaacacaa atgttttcac cagaattaac ttcaggatta ataaaagacg 1440 tgtttagtaa agtagatgaa tttagagagc cattaaaata tgttgtagag ctgcagccga 1500 aataaaagat aaagtataaa gctaactgtg gatcctgggg gcaggaaatg gatgtagaga 1560 tatttccaca tcgactcctc agtgctgaga caactgaaaa attgttgaat aagcttgggg 1620 agattgaagg tataaaaaga atgataatac aaggtcaaag attaccagca ggagaacacc 1680 ctgatagacg agttataaat gtaaaaggtc aggatataga acttaaagtt aaaacaggga 1740 gaatatttgt agaaatagaa gataaaaaga caatggaaaa aattaaagaa gtttgcgatg 1800 aagtatttcc atttaaatat gaattaattc caggaacatt ctttagaaga caaaaaacgg 1860 tgactgatgc tataaaattt ggtaaggatg ttgataagtt accaacggag ttagtaggaa 1920 tgacagatac agtgctagat taaaagatag ggtatcaata ataccaaaaa caaaaaagaa 1980 aaaacgtgat taaatgattg gaagaacaac acatattgta gattgtaggg aaacaatggg 2040 gctaggtgaa ggaggaggtt tggcccaaag aggtacattt gctcaatgtg gtggcgatgt 2100 tgtagctgtt gcaatgtcac caggaagaag acatataact aaacccattt gtgaaataac 2160 ctttgcattg cgagaaaatg atataaaggt aagtactttg gtattaaatg ctggagctgg 2220 agttccaagt gatgcacctg aggctggggc gggagggctt tttggaatta ctcctgaaga 2280 ggcagaacaa ataggaagac ataaattggc tttggtacat ttgggagctg tcagatatca 2340 cataatctac aaggctcgtt taatactaag gaacgtctcg atggttcctt gcattattgt 2400 gtgtgaatat ccagtagatt ttgaggattt tgcaaaaatc ggtgttaaga cgcgtgcagt 2460 aatgcctgat aaacctcaaa caaaaggcat cgttgtagac attgtaagtg gggttgtgag 2520 aggcgaaacc tgcccccagg agaaattaga tgaaattgtt aataaagtta aaaaatggct 2580 taatgtttta acacgtttgg agtattaaat taggaggtgt ttagatatgg cccaattcta 2640 tcctggatct acgaaaatag ctgaaaatag aaggaaattt atgaacccag atgcagaatt 2700 agaaaaattg agagaaattt cagatgaaga tgtagttagg atattaggac atagagcccc 2760 tggtgaagaa tatccaagtg ttcatcctcc acttgaagaa ttagatgagc cagaagatcc 2820 aataaaagac attgttgaac caactgaagg tgcaaaagct ggagatagag tcagatatgt 2880 acaatttaca gattctgtgt attttgcacc agcacaacca tatattagat caagagcata 2940 tttatggaga tacagaggtg cagatgctgg tactttatca ggaagacaaa taattgaagc 3000 tagagagaga gacgttgaaa aaatagctaa agaattaata gaaacagagt tttttgatcc 3060 agctagaaca gggattagag gaaaatctgt tcatggacac tcactaagat tagatgaaaa 3120 tggaatgatg ttcgacatgt tacgaagaca ggtttatgat gaagaaactg gcagagtaaa 3180 aatggtcaag aatcagatcg gagatgaatt tgatgaacca atagaccttg gagaacctct 3240 tgatgaggaa actcttaaag aaaaaacgac aatatataga atagataata tcccttacag 3300 agaagataaa gatctccttg aaattgtaca aagaattcat caattaagat cagaagcagg 3360 attttcccct gaataattag gaggtgttta aatatggctg aagaaagaaa aaaattgttt 3420 gttgatgcat taaggaaaaa atttaaagaa gaacctaaag aaagaaaaac aactttctat 3480 actttaggtg gttggaaaca atctgaaaga aagaaagaat ttgtagagta tggtaaaaaa 3540 gttgcaaagg aaagaggcat acctgcatac aacccagaca ttggtactcc attaggacaa 3600 agagtcttaa tgccatatca agtttctacc acagatacat ttgttgaagg cgatgaccta 3660 cattttgtaa acaatctggc aatgcagcaa ttctgggatg acataagaag aactgttatt 3720 gtaggactaa atcatgcaca tagaattctt gaaaggagct taggtaaaga agtgacacca 3780 gaaactataa atcattattt agaaaccgta aaccacgcaa tgcctggagc tgcagtagta 3840 caggagcaca tggtagaaac acatccagga cttactgcag acagttatgt aaaagtattt 3900 acaggtaacg atgaattagc agatgaaata gaatcctgtt atttaataga tataaacaaa 3960 cagttcccag aacaccaagc tgagcaattg aaaaaagcta ttggacatac tatatggcaa 4020 gcagttagaa ttccaacaat agtttctaga acttgtgatg gtgcaactac atcaagatgg 4080 tcagcaatgc aaataggaat gtcaatgatt tctgcatata aacaagctgc tggagaagct 4140 gcaacggcag atttcgcata tgccgcaaaa catgcagaag ttatacattt aggtacattt 4200 ctacctgtta gaagagctag aggtgaaaat gaactaggag gagtaccatt tggatttcta 4260 gcagacattg tccagagtag cagagtacat tatgaagacc ctgtgagagt ggcattagat 4320 gtagtagctt ctggagcaat gctatatgac caaatatggc taggatctta catgtcaggt 4380 ggagtaggat tcacacaata tgctacagca tcgtataccg acaacatact tgatgatttc 4440 acatactatg gtaaagaata cgtagaagac aaatatggtg gactagcaga ggcaccacat 4500 gatttcgaca caatacttga tgtagcaacc gaagttacac tttacagtct tgaccaatat 4560 gaagaatatc caacattaat ggaagatcac tttggaggtt cacaaagagc agcgattgct 4620 gcagctgcat ctggatgttc aacagccttt gcagcaggca atgctcaagc aggattaagt 4680 ggttggtact tatcacaaat actacataaa gaatgtcatg caagactagg attctatggc 4740 tatgacttac aagaccaatg tggagctgca aacacatatt caattagaag tgatgaagga 4800 ttaccagctg aactacgtgg accgaactat ccaaactatg caatgaatgt tggtcatcta 4860 ggagaatatg caggtatagt tcaggcagca catattgcaa gaggagatgc cgattctcta 4920 aatccattgg ttaaagttgc attcgcagat gacaatctac cattcgattg gacaaatcca 4980 cgtggcgaat ttgctaaagg agcattacgt gaatttgagc cagagggcga aagagactta 5040 ataaggcctg ctggtaaata aattcttaac ataattcaaa attttttgat ttttttcttt 5100 tctatttttt ccaaaacttt ttaaagaatt agtaagtaat aacttagtta ataaagttaa 5160 aaggaggaat gatatggacc ccgcagtggc tagtttaggt attttggcac ttacaacagc 5220 ttctgcaatt ataggacaaa caattgagga tgtagagacc aatataggat cacaaagtaa 5280 cccaaattca caagtacagt tagcaccgca gatgggtaat ttacatagat tttttaataa 5340 ggcaatagct ggagaaccat ttgcatattg tacattttgt ggagtatccg gggcaataac 5400 agtcgcaacg ttatatctac atcttcctgc agttattgca ctggcaatag gtgcagcaat 5460 tacaacactt atatggttag catattcaac aactgcatat ttaggtagag tatctggatc 5520 agctactttt aatcaaccag tatttttaga tatgttaaca gagaacttag gaccaatagc 5580 tggacatgca tttatagtat ttttctgtat gactggagta gcatacttaa tgactttacc 5640 tgtaaaggga tttgcacatc cattcccaat acctgtcatt gggatgatat ggggaatgac 5700 tataggtgca ataggttcag cagttggcga tgtatactat ggagcagaag cggagttcgt 5760 acataaaaaa tttggaggag gaataccagt agctagtcat ggagatataa caagaaaggg 5820 agtgcttgga gctagaagtc ctatggaagt aggtaatttc acagttaaat atggatctcc 5880 tataacagga atggcatttg gattaatagt gctctccatc acgagaggtg tatataacat 5940 cgaataggtt tgaaaaaggg agtatacttg cagcatttct tttcgtaata ttgttgacag 6000 taataaataa cagatcagaa aaacacgcaa gagaaaagta tggaccatac aggagggagt 6060 aaattgatag atcctataac 6080 // |
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