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EBI DbfetchID J02088; SV 1; linear; genomic RNA; STD; VRL; 2397 BP. XX AC J02088; XX DT 02-JUL-1986 (Rel. 09, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 7) XX DE Feline sarcoma virus gag polyprotein gene, complete cds. XX KW c-myc proto-oncogene; fes oncogene; polyprotein. XX OS Feline sarcoma virus OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Gammaretrovirus. XX RN [1] RP 1-2397 RX DOI; 10.1016/0092-8674(82)90282-3 RX PUBMED; 6183005. RA Hampe A., Laprevotte I., Galibert F., Fedele L.A., Sherr C.J.; RT "Nucleotide sequences of feline retroviral oncogenes (v-fes) provide RT evidence for a family of tyrosine-specific protein kinase genes"; RL Cell 30(3):775-785(1982). XX CC the transforming polyprotein of the snyder-theilen strain of feline CC sarcoma virus (fesv) include the transforming gene (fes) product CC with tyrosine specific protein kinase activity. the encoded protein CC sequence was compared with the gene products of gardner-arnstein CC (ga) strain (see fesvgaonc), fps gene of avian fujinami sarcoma CC virus (see fsv), and src gene of avian sarcoma virus. the reported CC sequence contains a 145bp deletion against the ga strain, and the CC authors argue that they sequenced a defective clone. the missing CC nucleotides are denoted by n's (see fesvgaonc between 1818 and 1964 CC for presumed base sequence). the last 24 bases represent the CC sequence of feline leukemia virus. XX FH Key Location/Qualifiers FH FT source 1..2397 FT /organism="Feline sarcoma virus" FT /strain="snyder-theilen" FT /mol_type="genomic RNA" FT /db_xref="taxon:11772" FT CDS 1..2325 FT /codon_start=1 FT /product="gag polyprotein" FT /db_xref="GOA:P03338" FT /db_xref="HSSP:1FGK" FT /db_xref="InterPro:IPR008266" FT /db_xref="UniProtKB/Swiss-Prot:P03338" FT /protein_id="AAA43046.2" FT /translation="MGQTVTTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCKAEWVM FT MNVGWPREGTFSLDNISQVKKKIFAPGPHGHPDQVPYITTWRSLATDPPSWVRPFLPPP FT KPPTPLPQPLSPQPSAPLTSSLYPVVPKPDPPKPPVLPPDPSSPLIDLLTEEPPPYPGG FT HGPPPSGPRTPAASPIVSRLRERRENPAEESQALPLREGPNNRPQYWPFSASDLYNWKS FT HNPPFSQDPVALTNLIESILVTHQPTWDDCQQLLQALLTGEERQRVLLEARKQVPGEDG FT RPTQLPNVIDETFPLTHPREQVQLLAKKQVLQEALQALQVALCSQAKLQAQRELLQAKL FT EQLGPGEPPPVLLLQDDRHSTSSSEQEREGGRTPTLEILKSHISGIFRPKFSLPPPLQL FT VPEVQKPLHEQLWYHGALPRAEVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX FT XXXXXXXXXXXXXXASIPLLVDHLLRSQQPLTKKSGIVLNRAVPKDKWVLNHEDLVLGE FT QIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIG FT VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRD FT LAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESD FT VWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEP FT GQRPSFSAFYQELQSIRKRHR" FT mat_peptide 4..381 FT /product="protein p15" FT mat_peptide 382..591 FT /product="protein p12" FT mat_peptide 592..891 FT /product="protein p30" FT mat_peptide 892..2256 FT /product="v-fes transforming protein" FT variation 1269..1415 FT /note="t...145bp...t in strain ga; tt in sequence clone" XX SQ Sequence 2397 BP; 475 A; 751 C; 618 G; 408 T; 145 other; atgggccaaa ctgtaactac ccccttaagc ctcacccttg accactggtc cgaggtccgg 60 gcacgagccc ataatcaggg tgtcgaggtc cggaaaaaga aatggattac tttatgtaaa 120 gccgaatggg tgatgatgaa tgtaggctgg ccccgagaag gaactttttc tcttgataac 180 atttctcagg ttaagaagaa gatcttcgcc ccgggaccac atggacaccc cgaccaagtt 240 ccttacatta ccacatggag atccttggcc acagaccccc cttcatgggt tcgcccgttc 300 ctaccccccc ccaaacctcc cacacccctc cctcagcctc tttcgccgca gccctccgcc 360 ccccttacct cctccctcta ccccgttgtc cccaagccag acccccccaa accgcctgtg 420 ttaccgcctg atccttcttc ccctttaatt gatctcttaa cagaagagcc acctccctat 480 ccggggggtc acgggccacc gccatcaggc cctaggaccc cggccgcttc cccgattgta 540 agccggctaa gggaacgccg agaaaaccct gctgaagagt ctcaagccct ccccttgagg 600 gaaggcccca acaaccgacc ccagtattgg ccattctcgg cctcagacct gtataattgg 660 aagtcgcata accccccttt ctcccaagac ccggtggccc taactaacct aattgagtcc 720 attttagtaa cgcaccaacc aacctgggac gactgccagc aactcttgca ggcactcctg 780 acaggcgaag aaaggcaaag agtccttctt gaggcccgaa agcaagttcc aggcgaagac 840 gggcggccaa cccaactgcc caatgtcatt gacgagactt tccccttgac ccacccccgg 900 gagcaggtgc agctgctggc caagaagcag gtgttgcaag aggcgctgca ggcgctgcag 960 gtggcgttgt gcagccaggc caagctgcag gcccagcggg agctgctgca ggccaagctg 1020 gagcagctgg gccccggcga gcccccgccc gtcctgctcc tgcaggatga ccgccactcc 1080 acgtcgtcct cggagcagga gcgagaaggg ggaaggacac ccaccttgga gatccttaag 1140 agccacatct caggaatctt ccgccccaag ttctcgctcc ctccacccct gcagctcgta 1200 ccagaggtgc agaagcccct gcacgagcag ctgtggtacc acggggccct cccacgggca 1260 gaggtggctn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1320 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1380 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnttgcga gcatcccctt gctcgtcgac 1440 cacctgctgc gctcccagca gcccctcacc aagaagagcg gtattgtcct caacagggct 1500 gtgcccaagg acaagtgggt gctaaaccac gaggacctgg tgttgggtga gcagatcggg 1560 cgggggaact ttggagaagt gttcagtgga cgcctgaggg ccgacaacac tctagtggcc 1620 gtgaaatctt gtcgcgagac actcccacct gacatcaagg ccaagtttct tcaggaagca 1680 aagatcctga agcagtacag ccaccccaac atcgtgcgtc tcatcggcgt ctgcacccag 1740 aagcagccca tctacatcgt catggagctc gtgcaggggg gcgacttcct gaccttcctg 1800 aggacggagg gagcccgcct gcggatgaag acgctgctgc agatggtggg cgacgcggcc 1860 gcgggcatgg agtacctgga gagcaagtgc tgcatccacc gggacctagc tgctcggaac 1920 tgcctggtga cggagaagaa cgtcctgaag atcagtgact tcgggatgtc ccgggaggaa 1980 gccgatgggg tctacgcggc ctcagggggc ctcagactag ttccggtgaa gtggacggca 2040 cccgaggctc ttaactacgg ccgctattcc tctgagagcg acgtgtggag cttcggcatc 2100 ttgctatggg agaccttcag cctgggcgcc tccccctacc ccaacctcag caatcagcag 2160 acccgcgagt ttgtggaaaa gggtggccgc ctgccctgcc ccgagctgtg ccccgacgct 2220 gtgttcaggc tcatggagca gtgctgggcc tacgagcccg ggcagcggcc cagcttcagc 2280 gccttctacc aggagctgca gagcatccga aagcggcatc ggtgaggccg gccctgcttc 2340 tcaagccggc ggcctcgaca ggcaagatcg tacctcctcc tgccccttgt tctatac 2397 // |
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