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EBI DbfetchID J02087; SV 1; linear; genomic RNA; STD; VRL; 2946 BP. XX AC J02087; XX DT 02-JUL-1986 (Rel. 09, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 4) XX DE feline sarcoma virus (gardner-arnstein) transforming gene. XX KW c-myc proto-oncogene; fes oncogene; polyprotein. XX OS Gardner-Arnstein feline leukemia oncovirus B OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Gammaretrovirus. XX RN [1] RP 1-2946 RX DOI; 10.1016/0092-8674(82)90282-3 RX PUBMED; 6183005. RA Hampe A., Laprevotte I., Galibert F., Fedele L.A., Sherr C.J.; RT "Nucleotide sequences of feline retroviral oncogenes (v-fes) provide RT evidence for a family of tyrosine-specific protein kinase genes"; RL Cell 30(3):775-785(1982). XX CC the transforming polyprotein of the gardner-arnstein strain of CC feline sarcoma virus (fesv) include the transforming gene (fes) CC product with tyrosine specific protein kinase activity. the encoded CC protein sequence was compared with the gene products of CC snyder-theilen strain (see fesvstonc), fps gene of avian fujinami CC sarcoma virus (see fsv), and src gene of avian sarcoma virus. the CC last 24 bases represent the sequence of feline leukemia virus. XX FH Key Location/Qualifiers FH FT source 1..2946 FT /organism="Gardner-Arnstein feline leukemia oncovirus B" FT /mol_type="genomic RNA" FT /db_xref="taxon:11824" FT CDS 1..2874 FT /codon_start=1 FT /note="gag polyprotein" FT /db_xref="GOA:P03337" FT /db_xref="HSSP:1MN8" FT /db_xref="InterPro:IPR003036" FT /db_xref="UniProtKB/Swiss-Prot:P00542" FT /protein_id="AAA43041.1" FT /translation="MGQTITTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCEAEWVM FT MNVGWPREGTFSLDNISQVEKKIFAPGPYGHPDQVPYITTWRSLATDPPSWVRPFLPPP FT KPPTSLPQPLSPQPSAPLTSSLYPVLPKSDPPKPPVLPPDPSSPLIDLLTEEPPPYPGG FT HGPPPSGPRTPTASPIASRLRERRENPAEESQALPLREGPNNRPQYWPFSASDLYNWKS FT HNPPFSQDPVALTNLIESILVTHQPTWDDCQQLLQALLTGEERQRVLLEARKQVPGEDG FT RPTQLPNVIDETFPLTRPNWDFATPAGREHLRLYRQLLLAGLRGAARRPTNLAQVKQVV FT QGKEETPAAARADGTMGFSSELCSPQGHGAEQQMQEAELRLLEGMRKWMAQRVKSDREY FT AGLLHHMSLQDGGGRGTGPYSPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLGLL FT IRERQQLRKTYSEQWQQLQQELTKTHNQDIEKLKSQYRALARDSAQARRKYQEASKDKD FT RDKAKLEQLGPGEPPPVLLLQDDRHSTSSSEQEREGGRTPTLEILKSHISGIFRPKFSL FT PPPLQLVPEVQKPLHEQLWYHGALPRAEVAELLTHSGDFLVRESQGKQEYVLSVLWDGQ FT PRHFIIQSADNLYRPEGDGFASIPLLVDHLLRSQQPLTKKSGIVLNRAVPKDKWVLNHE FT DLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPN FT IVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESK FT CCIHRDLAARNCLVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGR FT YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQ FT CWAYEPGQRPSFSAIYQELQSIRKRHR" FT mat_peptide 4..381 FT /note="protein p15" FT mat_peptide 382..591 FT /note="protein p12" FT mat_peptide 592..1044 FT /note="protein p30" FT mat_peptide 1045..2871 FT /note="v-fes transforming protein" XX SQ Sequence 2946 BP; 645 A; 944 C; 840 G; 517 T; 0 other; atgggccaaa ctataactac ccccttaagc ctcacccttg atcactggtc tgaagtccgg 60 gcacgagccc ataatcaagg tgtcgaggtc cggaaaaaga aatggattac cttatgtgag 120 gccgaatggg tgatgatgaa tgtgggctgg ccccgagaag gaactttttc tcttgataac 180 atttcccagg ttgagaagaa gatcttcgcc ccgggaccgt atggacaccc cgaccaagtt 240 ccttacatta ccacatggag atccttagcc acagaccccc cttcgtgggt tcgtccgttc 300 ttaccccctc ccaaacctcc cacatccctc cctcaacctc tttcgccgca gccctccgcc 360 cctcttacct cttccctcta ccccgttctc cccaagtcag accctcccaa accgcctgtg 420 ttaccgcctg atccttcttc ccctttaatt gatctcttaa cagaagagcc acctccctat 480 ccagggggtc acgggccacc gccatcaggt cctaggaccc caaccgcttc cccgattgca 540 agccggctaa gggaacgacg agaaaaccct gctgaagaat ctcaagccct ccccttgagg 600 gaaggcccca acaaccgacc ccagtattgg ccattctcag cttcagacct gtataactgg 660 aagtcgcata accccccttt ctcccaagac ccagtggccc taactaacct aattgagtcc 720 attttagtga cgcatcaacc aacctgggac gactgccagc agctcttgca ggcactcctg 780 acaggcgaag aaaggcaaag ggtccttctt gaggcccgaa agcaggttcc aggcgaggac 840 ggacggccaa cccaactacc caatgtcatt gatgagactt tccccttgac ccgtcccaac 900 tgggattttg ctacgccggc aggtagggag cacctacgcc tttatcgcca gttgctatta 960 gcgggtctcc gcggggctgc aagacgcccc actaatttgg cacaggtaaa gcaagttgta 1020 caagggaaag aggaaacgcc agcagctgcc cgcgcggacg gcactatggg cttctcttcc 1080 gagctgtgca gcccccaagg ccatggggca gaacagcaga tgcaggaggc tgagctgcgg 1140 ttgctggaag gcatgagaaa gtggatggcc cagcgggtca agagtgacag ggaatatgca 1200 gggctgctgc accacatgtc gctgcaggac ggcggaggcc ggggcacggg cccctatagc 1260 cccatcagcc agtcctgggc cgagatcacc agccagacgg agggcctgag ccggttgctg 1320 aggcaacacg cggaggatct gaactcgggg cccctgagta agctgggcct gctgatccgg 1380 gagcggcagc agctgcgcaa gacctacagc gagcagtggc agcagctcca gcaggagctc 1440 accaagaccc acaaccagga catcgagaag ctgaagagcc agtaccgagc cctggcacgg 1500 gacagcgccc aggcccggcg caagtaccag gaggccagca aagacaaaga ccgcgacaag 1560 gccaagctgg agcagctggg ccccggcgag cccccgcccg tcctgctcct gcaggatgac 1620 cgccactcca cgtcgtcctc ggagcaggag cgagaagggg gaaggacacc caccttggag 1680 atccttaaga gccacatctc aggaatcttc cgccccaagt tctcgctccc tccacccctg 1740 cagctcgtac cagaggtgca gaagcccctg cacgagcagc tgtggtacca cggggccctc 1800 ccacgggcag aggtggctga gctgttgacg cactctgggg actttctggt gcgcgagagc 1860 cagggcaagc aggaatatgt gctgtcggtg ctgtgggacg gccagccccg ccacttcatc 1920 atccagtccg ctgacaacct ctaccgaccg gaaggagatg gctttgcgag catccccttg 1980 ctcgtcgacc acctgctgcg ctcccagcag cccctcacca agaagagcgg tattgtcctc 2040 aacagggctg tgcccaagga caagtgggtg ctaaaccacg aggacctggt gttgggtgag 2100 cagatcgggc gggggaactt tggagaagtg ttcagtggac gcctgagggc cgacaacact 2160 ctggtggccg tgaaatcttg tcgcgagaca ctcccacctg acatcaaggc caagtttctt 2220 caggaagcaa agatcctgaa gcagtacagc caccccaaca tcgtgcgtct catcggcgtc 2280 tgcacccaga agcagcccat ctacatcgtc atggagctcg tgcagggggg cgacttcctg 2340 accttcctga ggacggaggg agcccgcctg cggatgaaga cgctgctgca gatggtgggc 2400 gacgcggccg cgggcatgga gtacctggag agcaagtgct gcatccaccg ggacctagct 2460 gctcggaact gcctggtgac ggagaagaac gtcctgaaga tcagtgactt cgggatgtcc 2520 cgggaggcag ccgatgggat ctacgcggcc tcagggggcc tcagacaagt tccggtgaag 2580 tggacggcac ccgaggctct taactacggc cgctattcct ctgagagcga cgtgtggagc 2640 ttcggcatct tgctatggga gaccttcagc ctgggcgcct ccccctaccc caacctcagc 2700 aatcagcaga cccgcgagtt tgtggaaaag ggtggccgcc tgccctgccc cgagctgtgc 2760 cccgacgctg tgttcaggct catggagcag tgctgggcct acgagcccgg gcagcggccc 2820 agcttcagcg ccatctacca ggagctgcag agcatccgaa agcggcatcg gtgaggccgg 2880 ccctgcttct caagccggcg gcctcgacag gcaagatcgt acctcctcct gcccctggtt 2940 ttatac 2946 // |
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