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EBI DbfetchID DQ307574; SV 1; linear; mRNA; STD; MAM; 4869 BP. XX AC DQ307574; XX DT 01-JAN-2006 (Rel. 86, Created) DT 01-JAN-2006 (Rel. 86, Last updated, Version 1) XX DE Canis familiaris glycogen debranching enzyme (AGL) mRNA, complete cds. XX KW . XX OS Canis lupus familiaris (dog) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis. XX RN [1] RP 1-4869 RA Gregory B.L., Fyfe J.C.; RT "Glycogen storage disease type IIIa in curly coated retrievers"; RL Unpublished. XX RN [2] RP 1-4869 RA Gregory B.L., Fyfe J.C.; RT ; RL Submitted (28-NOV-2005) to the EMBL/GenBank/DDBJ databases. RL Microbiology & Molecular Genetics, Michigan State University, 2209 RL Biomedical & Physical Sciences, East Lansing, MI 48824, USA XX FH Key Location/Qualifiers FH FT source 1..4869 FT /organism="Canis lupus familiaris" FT /chromosome="6" FT /mol_type="mRNA" FT /db_xref="taxon:9615" FT gene 1..4869 FT /gene="AGL" FT CDS 171..4772 FT /codon_start=1 FT /gene="AGL" FT /product="glycogen debranching enzyme" FT /function="multifunctional enzyme acting as 1,4 FT alpha-D-glucan: 1,4 alpha-D-glucan 4 FT alpha-D-glycosyltransferase and amylo-1,6-glucosidase" FT /note="glycogen catabolism; transfer of short outer chain FT of alpha (1,4) linked glucose at branch point to another FT outer chain and subsequent removal of alpha (1,6) linked FT glucose residue" FT /db_xref="GOA:Q2PQH8" FT /db_xref="InterPro:IPR006421" FT /db_xref="InterPro:IPR008928" FT /db_xref="InterPro:IPR010401" FT /db_xref="InterPro:IPR013781" FT /db_xref="InterPro:IPR017853" FT /db_xref="UniProtKB/Swiss-Prot:Q2PQH8" FT /protein_id="ABC25005.1" FT /translation="MGHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAVT FT VYTNYPFPGETFNREKFRSLEWENPTEREDDSDKYCKLNLQQAGSFQYYFLQGNEKSGG FT GYIVVDPILYVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPL FT QTLGLSRSCYSLANQLELNPDFSRPNKKYTWSDVGQLVEKMKKEWNVLCITDVVYNHTA FT ANSKWIQEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVAEGKYKEKGVPALIENDHQM FT NCIRKIIWEDIFPKIQLWEFFQVDVYKAVEQFRRLLTQENRKITTKPDPKEHLKIIQDP FT EYRRLGCTVDMNIALATFIPHDKGPAAIDECCNWFRKRIEELNSEKHQLVNYHQEQAVN FT CLLGNVFYERMAGHGPKLGPVTRKHPLVTRYFTFPFEEMTVSTEESMIHNPNKACFLMA FT HNGWVMGDDPLRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEIT FT ATYFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNIFVTRLGISS FT LIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDITHDNECPIVH FT RSEYDALPSTTIVSMACCASGSTKGYDELVPHQISVVSEERFYTKWNPGASPSNTGEVN FT FQSGIIAARCAINKLHQELGAQGFIQVYVDQVDEDIVAVTRHSPSIHQSVVSVSRTAFR FT NPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYQKDKNSINGMPNITVEIREHIQ FT LSESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQF FT SPHFKSGSLAVENSDPILKIPFAFIASKLTLAELNQVLYRCEAEEQEDGGGCYDIPNWS FT SLKYAGLQGLMSVLAEIRPKNDLGHPFCDNLRSGDWMIDYVSNRLISRSGTIAEVGKWF FT QAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDIAWKQMSSFVQNGSTFVKHLSLGSVQM FT CGVGKCPSLPLLSPSLMDVPYRLNEITKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIA FT LRGLLLITGRYLEARNIILAFAGTLRHGLIPNLLGEGTYARYNCRDAVWWWLQCIQDYC FT KMVPNGLDILKCPVSRMYPTDDSVPLSAGTLDQPLFEVIQEVMQRHIQGIQFRERNAGP FT QIDRNMKDEGFNITAGVDEETGFVYGGNRLNCGTWMDKMGESDRARNRGIPATPRDGSA FT VEIVGLSKSTVRWLLELSKKRIFPYHEVRVKRHGKVVTISYDEWNKKIQDNFEKLFHVS FT EDPXDFNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAMVVAPELFTAEKAWKAL FT EIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPEWLWPVGYFLR FT AKLYFSKLMGPEANAKTVFLVKNILSRHYVHLERSPWKGLPELTNENGQYCPFSCETQA FT WSIATVLETLYDL" XX SQ Sequence 4869 BP; 1500 A; 924 C; 1047 G; 1397 T; 1 other; caactgcttc cctctgttct catctcccca ttggtggctt ccaacccgaa tttgggaatg 60 gggagctcgc ccacctgtta tctcggagca cactaatctc ttgggtaatt cattcgactt 120 cggagtcctt ttcattcttc tgaacgattt caagtcctct agaagccaaa atgggacaca 180 gtaagcagat tagaatctta cttctgaacg aaatggaaaa gctggaaaag accctcttca 240 gacttgaaca agggttcgag ctacagttcc gattaggccc cactttacag ggaaaagcag 300 ttactgtgta cacaaattac ccatttcccg gagaaacatt taatcgagaa aaattccgtt 360 ccctggaatg ggaaaaccca acagaaagag aagatgattc tgataaatac tgtaaactta 420 atcttcagca agctggatca tttcagtatt acttccttca aggaaatgag aaaagtggtg 480 ggggttacat agttgtggat cctattttat atgttggtgc tgataatcac gtattaccct 540 tggactgtgt tactctccag acatttttag ctaagtgttt gggacccttt gatgaatggg 600 aaagcagact tagagttgca aaagaatcag gttacaacat gattcatttt accccattac 660 agactcttgg gctatctaga tcatgctatt ctcttgccaa ccagttagaa ttaaatcctg 720 acttttcaag acctaataaa aaatatacct ggagtgatgt tgggcaacta gtggaaaaaa 780 tgaaaaagga atggaatgtt ctttgtatta ctgatgttgt ctacaaccat actgctgcta 840 atagtaaatg gatccaggaa catccagaaa gtgcatataa ccttgtaaat tctccacact 900 taaaacctgc ctgggtctta gacagagcac tgtggcattt atcatgtgac gttgcagaag 960 ggaaatacaa agaaaaagga gtacctgctt tgattgaaaa tgatcatcaa atgaattgca 1020 ttcgaaaaat aatttgggag gatatttttc caaagattca actctgggaa tttttccaag 1080 tagacgttta caaagcagtt gagcaattta gaagacttct tacacaagaa aataggaaaa 1140 taacaaccaa gcctgatcca aaggaacacc ttaagattat tcaggatcct gaatacagaa 1200 gacttggctg cactgtagat atgaacattg cactagcaac tttcatacca catgacaagg 1260 gcccagctgc aatcgatgaa tgctgtaatt ggttccgtaa gagaattgag gaattaaatt 1320 cagagaagca tcaactcgtg aattatcatc aggaacaggc agttaattgc cttttgggaa 1380 atgtgtttta tgaacgaatg gctggccacg gtcctaaatt aggacctgtc actagaaaac 1440 atccattagt taccagatat tttacgttcc catttgaaga aatgaccgtc tccacagaag 1500 agtctatgat tcataaccca aataaagctt gttttctgat ggcccataat ggatgggtaa 1560 tgggagatga tccccttcga aactttgctg aaccaggttc agaagtttac ctaaggagag 1620 agcttatttg ctggggagac agtgttaaat tacgctatgg gaataaacca gaggactgtc 1680 cttatctctg ggcacacatg aaaaaataca ctgaaataac tgcaacctat ttccagggag 1740 tacgtcttga taactgccac tcaacgcctc ttcatgtagc tgagtacatg ttggatgctg 1800 ctaggaaatt gcaacccaat ttgtatgtag tagctgaact gttcacagga agcgaagacc 1860 tggacaacat ctttgttact agacttggca ttagttccct aataagagag gcaatgagtg 1920 catataatag ccatgaagag ggcagattag tttacagata tggaggagaa cctgttggat 1980 cctttgttca gccctgtttg aggccactaa tgccagctat tgcacatgct ctgtttatgg 2040 atattaccca cgataatgag tgtcctattg tgcataggtc agaatatgat gctctcccaa 2100 gtaccacgat tgtttctatg gcatgttgtg ctagtggaag tactaaaggc tatgatgaat 2160 tagtgcctca tcagatttca gtggtttctg aagaacggtt ttatactaag tggaatcctg 2220 gagcatctcc atcaaataca ggtgaagtta atttccaaag tggaattatt gcagccagat 2280 gtgctatcaa taaacttcat caggagcttg gggcccaggg tttcattcag gtgtatgtgg 2340 atcaagttga tgaagacatt gtggcagtaa caagacattc acccagtatc catcagtctg 2400 ttgtgtctgt gtctagaact gctttcagga atcctaagac ttcattttac agcaaggaag 2460 tgcctcaaat gtgcatccct ggcaaaattg aagaagtagt tcttgaagct agaactattg 2520 agagaaatac aaaaccttat cagaaggata agaattcgat caatggaatg ccaaatatca 2580 cagtagaaat tagagaacat attcagctta gtgaaagtaa aattgttaag caagctggag 2640 ttgccacaaa aggacccaat gaatatattc aagaaataga atttgaaaac ttgtctccag 2700 gaagtgtcat tatattcaga gttagtcttg atccacatgc acaagtcgct gttggaattc 2760 ttcgaaatca tctgacacag tttagtcctc actttaaatc tggaagcctt gctgttgaaa 2820 actcagatcc tatattaaaa attccttttg cttttattgc ctcaaaatta actttggctg 2880 agctgaatca ggtactttac cgatgtgaag cagaagaaca agaagatggt ggaggctgtt 2940 atgacatacc aaactggtca tctcttaaat atgcaggtct ccaagggtta atgtccgtct 3000 tggcagaaat aaggccaaag aatgacttgg ggcatccctt ttgtgataat ttgagatctg 3060 gagattggat gattgactat gtcagtaacc ggcttatctc tcgatcagga actattgcag 3120 aagttggtaa atggttccag gctatgttct tctacctgaa gcaaatccca cgttatctta 3180 tcccatgtta ttttgatgct atattaattg gtgcatacac cactcttctg gatatagcat 3240 ggaagcagat gtcaagcttt gttcagaatg gttctacctt tgtgaaacac ctttcactgg 3300 gatcagtgca aatgtgtgga gtaggaaagt gcccttctct gccacttctt tcaccttcac 3360 ttatggatgt accatatagg ctaaatgaga tcacaaaaga aaaggagcaa tgttgtgtgt 3420 ctctagctgc aggcttacct catttttctt ctggtatttt ccgctgttgg ggaagggata 3480 cttttattgc actgagaggt ctactgctga ttactggacg ctatttagag gccaggaata 3540 ttattttagc atttgctggt accctgagac acggtctcat tcctaatctc ctgggtgaag 3600 gaacttatgc cagatacaat tgccgggatg ctgtgtggtg gtggctacag tgtattcagg 3660 attactgtaa aatggttcca aatggcctag acattctcaa gtgcccagtt tccagaatgt 3720 atcctacaga tgattctgtt cctttgtctg ccggcacact ggatcaacca ctgtttgaag 3780 taatacagga agtcatgcaa agacacatac agggcataca attccgagag aggaatgctg 3840 gtccacaaat agaccgaaac atgaaggacg aaggctttaa tataactgca ggggttgacg 3900 aagaaacagg atttgtttat ggaggaaatc gcttaaactg tggcacatgg atggataaaa 3960 tgggagaaag tgatagagct agaaacagag gaatcccagc cactccaaga gatgggtctg 4020 ctgtggaaat tgtgggcctg agtaaatcta ctgtccgctg gttgctggaa ttatccaaaa 4080 aaagaatttt cccttatcat gaagtcagag taaaaagaca tggaaaggtt gtgacaatct 4140 catatgatga gtggaacaaa aaaatacaag acaactttga aaagctattt catgtgtcag 4200 aagaccctyc agattttaat gaaaagcatc ctaacctggt tcacaaacgt ggcatataca 4260 aagatagtta tggagcttcc agcccttggt gtgactatca gctcaggcct aattttacca 4320 tagcaatggt tgtggcccct gagctcttta ctgcagagaa agcatggaaa gctctggaga 4380 ttgcagaaaa aaagctgctt ggtcccctag gcatgaaaac tttggatcca gacgatatgg 4440 tttattgtgg aatttatgac aatgccttag acaatgacaa ctacaatctt gctaaaggtt 4500 tcaattatca ccaaggacct gagtggctgt ggcccgttgg gtattttctt cgtgcaaaat 4560 tatatttttc taaattgatg ggtccagagg ccaatgccaa gactgtgttt ttggttaaaa 4620 acattctttc ccgacattat gttcatcttg agagatcccc ttggaaagga cttcctgaac 4680 tgaccaatga gaatggccaa tactgtcctt tcagctgtga aacacaagcc tggtcaatcg 4740 ctactgttct tgaaacactc tatgacttat agttgattca tgaatatgta ttaagtatac 4800 aatcacttat attatggaat gcaaggtcaa aatataatgt aaatgcttta tatgcacaga 4860 cgagtcatt 4869 // |
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