 |
|
EBI DbfetchID DQ102714; SV 1; linear; genomic DNA; STD; PRO; 12359 BP. XX AC DQ102714; XX DT 26-APR-2006 (Rel. 87, Created) DT 14-NOV-2006 (Rel. 89, Last updated, Version 2) XX DE Campylobacter jejuni strain MF8 lipooligosaccharide biosynthesis gene DE locus, partial sequence. XX KW . XX OS Campylobacter jejuni OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Campylobacteraceae; Campylobacter. XX RN [1] RP 1-12359 RX DOI; 10.1074/jbc.M512183200 RX PUBMED; 16481326. RA Houliston R.S., Endtz H.P., Yuki N., Li J., Jarrell H.C., Koga M., RA van Belkum A., Karwaski M.F., Wakarchuk W.W., Gilbert M.; RT "Identification of a sialate O-acetyltransferase from Campylobacter jejuni: RT demonstration of direct transfer to the C-9 position of terminalalpha-2, RT 8-linked sialic acid"; RL J. Biol. Chem. 281(17):11480-11486(2006). XX RN [2] RP 1-12359 RA Gilbert M., Karwaski M.-F., Godschalk P.C.R., Brochu D., Endtz H.P., RA Masotti M.; RT "Sequencing of the lipooligosaccharide biosynthesis locus of Campylobacter RT jejuni MF8"; RL Unpublished. XX RN [3] RP 1-12359 RA Gilbert M., Karwaski M.-F., Godschalk P.C.R., Brochu D., Endtz H.P., RA Masotti M.; RT ; RL Submitted (23-JUN-2005) to the EMBL/GenBank/DDBJ databases. RL Institute for Biological Sciences, National Research Council of Canada, 100 RL Sussex Drive, Ottawa, Ontario K1A 0R6, Canada XX FH Key Location/Qualifiers FH FT source 1..12359 FT /organism="Campylobacter jejuni" FT /strain="MF8" FT /serotype="HS:23/HS:36" FT /mol_type="genomic DNA" FT /db_xref="taxon:197" FT misc_feature <1..>12359 FT /note="lipooligosaccharide biosynthesis gene locus" FT gene <1..335 FT /gene="waaC" FT CDS <1..335 FT /codon_start=3 FT /transl_table=11 FT /gene="waaC" FT /product="heptosyltransferase I" FT /db_xref="GOA:Q1L4C1" FT /db_xref="InterPro:IPR002201" FT /db_xref="UniProtKB/TrEMBL:Q1L4C1" FT /protein_id="AAZ80456.1" FT /translation="LNLSGIDETHIELAPKFNLEELMAFTKMMDLIIGNDSGPTHLAFA FT LNKASITIFGATPSYRNAFQTHINKIIDTGKKIQNAKHIDKSDFCITRIEEEDIFKLAK FT GLLNEK" FT gene 325..1212 FT /gene="htrB" FT CDS 325..1212 FT /codon_start=1 FT /transl_table=11 FT /gene="htrB" FT /product="lipid A biosynthesis acyltransferase" FT /db_xref="GOA:Q9K379" FT /db_xref="InterPro:IPR004960" FT /db_xref="UniProtKB/TrEMBL:Q9K379" FT /protein_id="AAZ80457.1" FT /translation="MKNSDRIYLSLYYILKFFVTFMPDCILHFLALIVARIAFHLNKKH FT RKIINTNLQICFPQYTQKERDKLSLKIYENFAQFGIDCLQNQNTTKEKILNKVNFINEN FT FLIDALALKRPIIFTTAHYGNWEILSLAYAAKYGAISIVGKKLKSEVMYEILSQSRTQF FT DIELIDKKGGIRQMLSALKKERALGILTDQDCVENESVRLKFFNKEVNYQMGASLIAQR FT SNALIIPVYAYKEGGKFCIEFFKAKDSQNASLEELTLYQAQSCEEMIKKRPWEYFFFHR FT RFASYNEEIYKGAK" FT CDS 1209..2756 FT /codon_start=1 FT /transl_table=11 FT /product="putative two-domain glucosyltransferase" FT /note="orf3" FT /db_xref="GOA:Q93D08" FT /db_xref="InterPro:IPR019290" FT /db_xref="UniProtKB/TrEMBL:Q93D08" FT /protein_id="AAZ80458.1" FT /translation="MNLKQISVIIIVKNAEQTLLECLNSLKDFDEIILLNNESIDNTLN FT IANEFKKDFANLYIYHNAFIGFGALKNLALSYAKNDWILSIDADEVLENECIKELKNLE FT LQEDNIIALSRKNLYKGEWIKACGWSPDYVLRIFNKNFTRFNDNLVHESLVLPSNVKKI FT HLKNGLKHYAFRDISHLINKMQYYSSLWAKQNIHKKSGVLKANLRAFWTFFRNYFLKNG FT FLYGYQGFTISVCNALGTFFKYMKLYELQKQKPKTCALIITTYNQKERLKLVLDSVKNL FT TFLPNEVLIADDGSKEDTARLIEEYQKDFPCSLKHIWQEDEGFRAAKNRNNAIRVSKSE FT YIILIDGDMILEKDFIKNHFEFAKRKVILQGSRVILNKNESEEILKNDDYSLAFSKKDF FT KSYKNSFLAKIIYKISKIDQKFFNTKEIIKGSKTCNMSFFKADFDELDGFNENFIGWGR FT EDSEFVARFLFNKGIFRRLKFKAIAYHIYHEENSKKMLESNHQIYLDTIKNKKISWR" FT CDS 2760..2855 FT /codon_start=1 FT /transl_table=11 FT /product="truncated putative glycosyltransferase" FT /note="orf4; premature translation stop due to frameshift FT mutation" FT /db_xref="GOA:Q93D07" FT /db_xref="UniProtKB/TrEMBL:Q93D07" FT /protein_id="AAZ80459.1" FT /translation="MKKIGVVIPIYNVEEYLRECLTASSIKLILT" FT gene 3975..4235 FT /gene="cgtA-I" FT CDS 3975..4235 FT /codon_start=1 FT /transl_table=11 FT /gene="cgtA-I" FT /product="truncated FT beta-1,4-N-acetylgalactosaminyltransferase" FT /note="orf5-I; premature translation stop due to deletion" FT /db_xref="GOA:Q93D06" FT /db_xref="InterPro:IPR010446" FT /db_xref="UniProtKB/TrEMBL:Q93D06" FT /protein_id="AAZ80460.1" FT /translation="MLFQSYFVKIICLFIPFRKIRHKIKKTFLLKNIQRDKIDSYLPKK FT ILIQINKYNNEDLIKLNKAITGGGIKDILIMMKNLKIQNLL" FT gene complement(5003..5908) FT /gene="cgtB" FT CDS complement(5003..5908) FT /codon_start=1 FT /transl_table=11 FT /gene="cgtB" FT /product="beta-1,3-galactosyltransferase" FT /db_xref="GOA:Q9K2V8" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q9K2V8" FT /protein_id="AAZ80461.1" FT /translation="MFKISIILPTYNVEQYIARAIESCINQTFKDIEIIVVDDCGNDNS FT INIAKEYSKKDKRIKIIHNEKNLGLLRARYEGVKVANSPYIMFLDPDDYLELNACEECI FT KILDEQDEVDLVFFNAIVESNVISYKKFDFNSGFYSKKEFVKKIIAKKNLYWTMWGKLI FT RKKLYLEAFASLRLEKDVKINMAEDVLLYYPMLSQAQKIAYMNCNLYHYVPNNNSICNT FT KNEVLVKNNIQELQLVLNYLRQNYILNKYCSVLYVLIKYLLYIQIYKIKRTKLMVTLLA FT KINILTLKILFKYKKFLKQC" FT gene 5997..6872 FT /gene="cst-II" FT CDS 5997..6872 FT /codon_start=1 FT /transl_table=11 FT /gene="cst-II" FT /product="alpha-2,3-sialyltransferase" FT /db_xref="GOA:Q93D05" FT /db_xref="InterPro:IPR009251" FT /db_xref="UniProtKB/TrEMBL:Q93D05" FT /protein_id="AAZ80462.1" FT /translation="MKKVIIAGNGPSLKEIDYSRLPNDFDVFRCNQFYFEDKYYLGKKC FT KTVFYTPNFFFEQYYTLKHLIQNQEYETELIMCSNYNQAHLENENFVKTFYDYFPDAHL FT GYDFFKQLKEFNAYFKFHEIYFNQRITSGVYMCAVAIALGYKEIYLSGIDFYQNGSSYA FT FDTKQENLLKLAPDFKNDRSHYIGHSKNTDIKALEFLEKTYKIKLYCLCPNSLLANFIE FT LAPNLNSNFIIQEKNNYTKDILIPSSEAYGKFSKNINFKKIKIKENVYYKLIKDLLRLP FT SDIKHYFKGK" FT gene 6873..7913 FT /gene="neuB1" FT CDS 6873..7913 FT /codon_start=1 FT /transl_table=11 FT /gene="neuB1" FT /product="sialic acid synthase" FT /db_xref="GOA:Q93D04" FT /db_xref="InterPro:IPR020007" FT /db_xref="UniProtKB/TrEMBL:Q93D04" FT /protein_id="AAZ80463.1" FT /translation="MKEIKIQNIIISEEKAPLVVPEIGINHNGSLELAKIMVDAAFSAG FT AKIIKHQTHIVEDEMSKAAKKVIPGNAKISIYEIMQKCALDYKDELALKEYTEKLGLVY FT LSTPFSRAGANRLEDMGVSAFKIGSGECNNYPLIKHIAAFKKPMIVSTGMNSIESIKPT FT VKILLDNEIPFVLMHTTNLYPTPHNLVRLNAMLELKKEFSCMVGLSDHTTDNLACLGAV FT ALGACVLERHFTDSMHRSGPDIVCSMDTKALKELIIQSEQMAIMKGNNESKKAAKQEQV FT TIDFAFASVVSIKDIKKGEVLSMDNIWVKRPGLGGISAAEFENILGKKALRDIENDTQL FT SYEDFA" FT gene 7910..9034 FT /gene="neuC1" FT CDS 7910..9034 FT /codon_start=1 FT /transl_table=11 FT /gene="neuC1" FT /product="UDP-N-acetylglucosamine FT 2-epimerase/N-acetylmannosamine synthase" FT /db_xref="GOA:Q93D03" FT /db_xref="InterPro:IPR020004" FT /db_xref="UniProtKB/TrEMBL:Q93D03" FT /protein_id="AAZ80464.1" FT /translation="MKKILFITGTRADYSKIKSLMYRVQNSSEFELYIFATGMHLSKNF FT GYTVKELYKNGFKNIYEFINYDKYYQTDKALATTIDGFSRYVNELKPDLIVVHGDRIEP FT LAAAIVGALNNILVAHIEGGEISGTIDDSLRHAISKLAHIHLVNDEFAKRRLMQLGEDE FT KSIFIIGSPDLELLNDNKISLSEAKKYYDINYENYALLMFHPVTTEITSIKNQADNLVK FT ALIQSNKNYIVIYPNNDLGFELILQSYEELKNNPRFKLFPSLRFEYFITLLKNADFIIG FT NSSCILKEALYLKTAGILVGSRQNGRLGNENTLKVNANSDEILKAINTIHKKQDLFSTK FT LEILDSSKLFFEYLLSGEFFKLSTQKVFKDIKHA" FT gene 9027..9974 FT /gene="cgtA-II" FT CDS 9027..9974 FT /codon_start=1 FT /transl_table=11 FT /gene="cgtA-II" FT /product="beta-1,4-N-acetylgalactosaminyltransferase" FT /note="orf5-II; contains phase variable poly-G tract" FT /db_xref="GOA:Q934C5" FT /db_xref="InterPro:IPR010446" FT /db_xref="UniProtKB/TrEMBL:Q934C5" FT /protein_id="AAZ80465.1" FT /translation="MLKKIISLYKRYSISKKLVLDNEHFIKENKNIYGKKHKGFFDFDE FT KAKDVKSPLNPWGFIRVKNEALTLRVSLESILPALQRGIIAYNDCDDGSEELILEFCKQ FT YPNFIAKKYPYKVDLENPKNEENKLYSYYNWAASFIPLDEWFIKIDVDHYYDAKKLYKS FT FYRIDQENKALCYPRINFIILNGNIYVQNSGNYGFIGGGDQLLIKRRNSSFIERRVSKK FT SQWIDPKGLIEELYSEQQVLSQGVKILQAPLLQWHFPALKYRRNDYQQYLDILSLEEFQ FT AFHRKSKEAKKIDFAMLKRPVIEQILKKFQGEIK" FT variation 9633^9634 FT /gene="cgtA-II" FT /replace="g" FT /note="results in truncated FT beta-1,4-N-acetylgalactosaminyltransferase" FT gene 9971..10636 FT /gene="neuA1" FT CDS 9971..10636 FT /codon_start=1 FT /transl_table=11 FT /product="CMP-Neu5Ac synthetase" FT /db_xref="GOA:Q933W2" FT /db_xref="HSSP:1EYR" FT /db_xref="InterPro:IPR003329" FT /db_xref="UniProtKB/TrEMBL:Q933W2" FT /protein_id="AAZ80466.1" FT /translation="MSLAIIPARGGSKGIKNKNLVLLNNKPLIYYTIKAALNAKSISKV FT VVSSDSDEILNYAKSQNVDILKRPISLAQDDTTSDKVLLHALKFYKDYEDVVFLQPTSP FT LRTNIHIDKAFNLYKNSNANALISVSECDNKILKAFVCNDYGDLAGICNDEYPFMPRQK FT LPKTYMSNGAIYILKIKEFLNNPSFLQNKTKHFLMDESSSLDIDCLEDLKKVEQIWKK" FT CDS 10624..11457 FT /codon_start=1 FT /transl_table=11 FT /product="putative acetyltransferase" FT /db_xref="GOA:Q93D02" FT /db_xref="HSSP:1MR9" FT /db_xref="UniProtKB/TrEMBL:Q93D02" FT /protein_id="AAZ80467.1" FT /translation="MEKITLKCNKNILNLLKQYNIYTKTYIENPRRFSRLKTKDFITIP FT LKNNQLESAAGLGIEEYCAFKFSNILHEMGSFSFSGSFLPHYAKVERYCSIADGVSMFN FT FQHPIDRISTASFTYETNHSFINDACQNHINKTFPIVNHNPSSSITHLIIQDDVWIGKD FT VLLKQGITLGTGCVIGQRAVVTKDVPPYAIVAGIPAKIIKYRFDEKTIERLLKIQWWRY FT HFADFYDIDLNLKINQYLDLLEEKIIKKSISYYNPNKLYFRDILELKSKKIFNLF" FT gene complement(11449..12276) FT /gene="waaV" FT CDS complement(11449..12276) FT /codon_start=1 FT /transl_table=11 FT /gene="waaV" FT /product="putative glycosyltransferase" FT /db_xref="GOA:Q93D01" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q93D01" FT /protein_id="AAZ80468.1" FT /translation="MPQLSIIIPLFNSCDFILRALQSCINQTLKDIEILIIDDKSKDNS FT LNMVLEFAKKDPRIKIFQNEENLGTFASRNLGVLHSSSDFIMFLDSDDFLTPGACEIAF FT KEMKKGFDLLCFDAFVHRVKTKQFYRFKQDGVFNQKEFLEFLSKQRHFCWSVWAKCFRK FT DIILKNFEKVKFEKVKIDERLSYGEDVLFCYVYFMFCEKIAVFKTCIYHYEFNPNGRYE FT NKNKEILNQNYYDKKKSNEIIKRLSKEFLHDEFHQKLFEVLEREEVGVKNRLK" FT gene 12257..>12359 FT /gene="waaF" FT CDS 12257..>12359 FT /codon_start=1 FT /transl_table=11 FT /gene="waaF" FT /product="heptosyltransferase II" FT /db_xref="GOA:Q5WQY7" FT /db_xref="UniProtKB/TrEMBL:Q5WQY7" FT /protein_id="AAZ80469.1" FT /translation="MIESCGIFFLNFVKIIKTILSKFRKFMKIFIHLP" XX SQ Sequence 12359 BP; 4826 A; 1649 C; 1778 G; 4106 T; 0 other; ttttaaatct tagtggtatt gatgaaacac atatagaatt agcgccaaaa tttaatcttg 60 aagagctaat ggcttttaca aaaatgatgg atcttatcat aggaaatgat agcggtccaa 120 cacatttagc ttttgcttta aataaagcat ctattacgat ttttggtgca acaccaagct 180 accgcaatgc ttttcaaact catatcaata aaatcattga tacaggtaaa aaaatccaaa 240 atgccaagca tatcgataaa agtgattttt gtatcacgcg tatagaagaa gaagatatct 300 tcaaacttgc caaaggctta cttaatgaaa aatagtgata gaatatatct tagtctttat 360 tatattttga aattttttgt tacttttatg cctgattgta tcttgcattt tttagctttg 420 attgtagcaa gaatcgcttt tcatcttaac aaaaaacacc gcaaaatcat caatacaaat 480 ttgcaaatct gttttcctca atacactcaa aaagaacgcg ataaattgtc tttaaaaatt 540 tatgaaaatt ttgctcaatt tgggattgat tgtttgcaaa atcaaaacac caccaaagaa 600 aaaattctca ataaagtaaa tttcatcaat gaaaattttc ttatagatgc cctggcttta 660 aagcgtccta ttatcttcac aactgcacac tatggaaact gggaaatttt aagccttgct 720 tatgcggcta aatatggtgc gatttccata gtgggaaaaa agttaaaaag tgaagttatg 780 tatgaaattt taagccaaag tcgcacccaa tttgacatag aacttattga caaaaaaggc 840 ggtataagac aaatgctaag tgctctaaaa aaggagagag ctttgggaat tttaactgat 900 caagactgcg tagaaaacga aagcgtaaga ttaaaatttt ttaacaaaga agtgaattat 960 caaatgggag caagccttat cgcacaaaga agcaatgctt tgatcatccc tgtttatgcc 1020 tataaagaag gtggtaaatt ttgcatagag ttttttaaag caaaagattc tcaaaatgca 1080 agtttagaag aactgacact ttatcaagca caaagttgcg aagaaatgat taaaaaaaga 1140 ccttgggaat actttttttt tcatagacgc tttgctagtt ataatgagga aatttacaag 1200 ggtgcaaaat gaatctaaag caaataagcg ttattatcat cgtaaaaaat gctgagcaaa 1260 ctttgcttga gtgtttaaat tctttaaaag attttgatga aattatttta cttaacaatg 1320 aaagcattga taatacccta aatatagcta atgaatttaa aaaagatttt gctaatttat 1380 atatttatca caatgctttt ataggttttg gagctttaaa aaatcttgcc ttaagctatg 1440 caaaaaatga ttggatttta agcattgatg ctgatgaagt acttgaaaat gagtgtatta 1500 aagagcttaa aaatttagaa cttcaagaag ataatatcat cgcacttagt cggaaaaatc 1560 tctataaagg cgaatggata aaggcttgtg gttggtcgcc tgattatgtt ttaagaattt 1620 ttaataaaaa tttcactcgt tttaatgata atttagtgca tgaaagcctt gttttaccaa 1680 gtaatgttaa aaaaattcat cttaaaaatg gattgaagca ttatgctttt agagatattt 1740 ctcacttaat caataaaatg cagtactact caagcctttg ggcaaaacaa aatatacata 1800 aaaaaagtgg tgttttaaaa gcaaatttaa gagctttttg gacttttttt agaaattatt 1860 ttttaaaaaa tggctttttg tatggttatc aaggctttac gatcagcgtt tgcaatgcct 1920 tagggacttt ttttaaatat atgaaattat atgaacttca aaagcaaaag ccaaaaactt 1980 gtgctttaat aataacaacc tataatcaaa aagaacgcct taaattagtg cttgatagtg 2040 ttaaaaatct aaccttttta cccaatgaag ttttaatcgc agatgatggt agcaaagaag 2100 atacagcaag gcttattgaa gaatatcaaa aagattttcc ttgctcttta aaacacattt 2160 ggcaagaaga tgagggtttt cgcgctgcaa aaaatagaaa taatgccatt agagtttcta 2220 aaagtgaata tataatttta attgacggtg atatgatttt agaaaaagac tttataaaaa 2280 atcatttcga atttgcgaaa cgcaaagtaa ttttacaagg ttcaagagta attttaaata 2340 aaaatgaaag cgaagaaatc ttaaaaaatg atgattatag tttagctttt agtaaaaaag 2400 attttaaaag ctataaaaat tcttttttag ccaaaattat ctataaaatt tcaaaaatag 2460 atcaaaaatt ttttaatacc aaagaaataa taaagggaag taaaacctgc aatatgagtt 2520 tttttaaagc cgattttgat gaacttgatg gttttaatga aaattttatt ggttggggta 2580 gagaagatag tgaatttgtg gctagatttt tatttaataa aggcattttt agacgcttaa 2640 aatttaaagc tattgcttat catatttatc atgaagaaaa tagcaaaaaa atgctcgaaa 2700 gcaatcatca aatttattta gataccatca aaaataaaaa aatttcttgg agataaaaca 2760 tgaagaaaat aggtgtagtt ataccaatat acaacgtaga agaatatttg agagaatgtt 2820 taacagcgtc atcaatcaaa cttatactaa cttagaaatc atacttgtaa atgatggtag 2880 tacagatgaa aactcactca atatagccaa agaatatact ttaaaagatg aaagatttat 2940 actttttgat aagaaaaatg ggggtttaag ttcagctaga aatgtaggta tagaatactt 3000 tagtggggag tataaattaa aaaacaaaac tcaacatata aaagaaaatt ctttaataga 3060 atttcaattg gatggtaata atccttataa tatatataaa gcatataaaa gctctcaagc 3120 ttttaataat gaaaaagatt taactaattt tacttatcct aatatagatt atattatatt 3180 tttagattct gatgattatt gggagttaaa ctgcatagaa gaatgtgtta taagaatgaa 3240 aaatgtggat gtattgtggt ttgaccatga ttgcacctat gaagacaata taaaaaataa 3300 gcacaaaaaa acaaggatgg aaatttttga ttttaaaaaa gaatgtataa tcactccaaa 3360 agaatatgca aatcgagcat taagtgtagg atctagagat atttcttttg gatggaatgg 3420 aatgattgat tttaattttt taaagaaaat taaacttaaa tttataaatt ttattatcaa 3480 tgaagatata cactttggga taattttgtt tgctagtgct aataaaattt atattttatc 3540 acaaaagttg tatttatgcc gtttaagagc aaacagtata tcaaatcatg ataagaagat 3600 tacaaaagca aatgtgtcag agtattttaa agatatatat gaaactttcg gggaaaacgc 3660 taaggaagca aaaaattatt taaaagcagc aagcagggtt acaactgctt taaaattgat 3720 agaatttttt aaagatcaaa aaagcgaaaa tgcacttgct ataaaagaaa catttttacc 3780 ttgctatgcc aaaaaagctt taatgattaa aaaatttaaa aaagatcctt taaatttaaa 3840 ggaacaatta gttttaatta agccttttat tcaaacaaaa cttccttacg atatttggaa 3900 attttggcaa aaaataaaaa aaattaatta atttttaggt ataatcacta taattatagg 3960 agaaaatatt ttatatgcta tttcaatcat actttgtgaa aataatttgc ttattcattc 4020 cttttagaaa aattagacat aaaataaaaa aaacattttt actaaaaaac atacaacgag 4080 ataaaatcga ttcttatcta ccaaaaaaaa ttcttataca aattaataaa tacaacaatg 4140 aagatttaat taaacttaat aaagctatta caggaggggg cataaaggat attttaatta 4200 tgatgaaaaa tctaaagatc caaaatctcc tttgaatcct tgggctttta tacgagtaaa 4260 aaatgaagtt attaccttaa aagcttctct tgaaagtata ttgcctgcta tccaaagagg 4320 tgttatagga tataatgatt gtaccgatgg aagtgaagaa ataattctag aattttgcaa 4380 acaatatcct tcatttatac caataaaata tccttatgaa attcaaattc aaaacccaaa 4440 atcagaagaa aataaactct atagctatta taattatgtt gcaagtttta taccaaaaga 4500 tgagtggctt ataaaaatag atgtggatca tatctatgat gctaaaaaac tttataaaag 4560 cttctatata ccaaaaaaca aatatgatgt agttagttat tcaagggttg atattcacta 4620 ttttaatgat aatttttttc tttgtaaaga taataatggc aatatattga aagaaccagg 4680 agattgcttg cttatcaata attataactt aaaatggaaa gaagtattaa ttgacagaat 4740 caataacaat tggaaaaaag caacaaaaca aagtttttct tcaaatatac actctttaga 4800 gcaattaaag tataaacaca ggatattatt tcacactgaa ttaaataatt atcattttcc 4860 ttttttaaaa aaacatagag ctcaagatat ttataaatat aattggataa gtattgaaga 4920 atttaaaaaa ttctatttac aaaatattaa tcataaaata gaaccttcta tgatttcaaa 4980 agaaactcta aaaaaaatat tcttaacatt gttttaaaaa ttttttatat ttaaataaaa 5040 tttttaaagt taaaatattt attttagcta acaatgtaac cattaatttt gttcttttta 5100 ttttatatat ttgaatatat agcaaatatt taattagcac atagagaacg ctacaatact 5160 tgtttaaaat ataattttgc cttaaatagt ttaaaaccaa ctgcaactct tgaatattat 5220 ttttaacaag cacttcattc ttagtattac aaattgaatt attattaggc acgtaatgat 5280 ataaattaca gttcatatat gctatttttt gagcttgact taacattgga taatataaca 5340 atacatcttc agccatattg attttaacat ctttctcgag tcttaaactc gcaaaagctt 5400 ctaaatacaa tttctttctt ataagtttcc cccacatagt ccaatataaa tttttctttg 5460 caataatttt tttcacaaac tcttttttgc tataaaaacc agaattaaag tcaaactttt 5520 tatatgaaat aacattactt tcaacaatag cattgaaaaa cactaaatca acttcatcct 5580 gttcatctaa aatttttata cactcttcac aagcatttag ttccaaataa tcatcaggat 5640 ctaaaaacat tatataagga gagtttgcta ctttcacacc ttcatatctt gctcttaaaa 5700 gacctaagtt tttttcattg tggattattt ttattctttt gtctttttta gagtattctt 5760 tggctatatt tatactatta tcatttccac aatcatcaac tacaattatt tctatatctt 5820 taaaagtctg attgatacag ctttctattg cccttgctat atattgttcc acattataag 5880 ttggtaagat gattgaaatt ttaaacatat ttatttctta ttttattata atttaattat 5940 aacataaaat ctattttgat aaaatcgtta aaaataaatc ttgatggaaa ataatcatga 6000 aaaaagttat tattgctgga aatggaccaa gtttaaaaga aattgattat tcaaggctac 6060 caaatgattt tgatgtattt agatgtaatc aattttattt tgaagataaa tactatcttg 6120 gtaaaaaatg caaaacagtg ttttacaccc ctaatttctt ctttgagcaa tactacactt 6180 taaaacattt aatccaaaat caagaatatg agaccgaact aattatgtgt tctaattaca 6240 accaagctca tctagaaaat gaaaattttg taaaaacttt ttacgattat tttcctgatg 6300 ctcatttggg atatgatttt tttaaacaac ttaaagaatt taatgcttat tttaaatttc 6360 acgaaattta tttcaatcaa agaattacct caggggtcta tatgtgtgca gtagccatag 6420 ccctaggata caaagaaatt tatctttcgg gaattgattt ttatcaaaat gggtcatctt 6480 atgcttttga taccaaacaa gaaaatcttt taaaactagc ccctgatttt aaaaatgatc 6540 gctcacacta tatcggacat agtaaaaata cagatataaa agctttagaa tttctagaaa 6600 aaacttacaa aataaaacta tattgcttat gtcctaatag tcttttagca aattttatag 6660 aactagcgcc aaatttaaat tcaaatttta tcatacaaga aaaaaataac tacactaaag 6720 atatactcat accttctagt gaggcttatg gaaaattttc aaaaaatatt aattttaaaa 6780 aaataaaaat taaagaaaat gtttattaca agttgataaa agatctatta agattaccta 6840 gtgatataaa gcattatttc aaaggaaaat aaatgaaaga aataaaaata caaaatataa 6900 tcataagtga agaaaaagca cccttagtcg tgcctgaaat aggcattaat cataatggca 6960 gtttagaact agctaaaatt atggtagatg cagcctttag cgcaggtgct aagattataa 7020 agcatcaaac ccacatcgtt gaagatgaga tgagtaaggc cgctaaaaaa gtaattcctg 7080 gtaatgcaaa aataagcatt tatgagatta tgcaaaaatg tgctttagat tataaagatg 7140 agctagcact taaagaatac acagaaaaat taggtcttgt ttatcttagc acaccttttt 7200 ctcgtgcagg tgcaaaccgc ttagaagata tgggagttag tgcttttaag attggttcag 7260 gtgagtgtaa taattatccg cttattaaac acatagcagc ctttaaaaag cctatgatag 7320 ttagcacagg aatgaatagt attgaaagta taaaaccaac tgtaaaaatc ttattagaca 7380 atgaaattcc ctttgtttta atgcacacga ccaatcttta cccaaccccg cataatcttg 7440 taagattaaa cgctatgctt gaattaaaaa aagaattttc ttgcatggta ggcttaagcg 7500 accacacaac agataatctt gcgtgtttag gtgcggttgc acttggtgct tgtgtgcttg 7560 aaagacattt tactgatagt atgcatagaa gtggccctga tatagtttgt tctatggata 7620 caaaggcttt aaaagagcta attatccaaa gtgagcaaat ggctataatg aaaggaaata 7680 atgaaagcaa aaaagcagct aagcaagaac aagttacaat tgattttgcc tttgcaagcg 7740 tagttagcat taaagatatt aaaaaaggcg aagttttatc tatggacaat atctgggtta 7800 aaagacctgg acttggtgga attagtgcgg ctgaatttga aaatatttta ggcaaaaaag 7860 cattaagaga tatagaaaat gatactcagt taagctatga ggattttgcg tgaaaaaaat 7920 cctttttata acaggcacca gggctgatta ttctaagatt aaatctttaa tgtatagggt 7980 gcaaaactca agcgaatttg agctttacat ctttgcaaca ggaatgcact taagcaaaaa 8040 ttttggctat acagttaaag agctttataa aaatggcttt aaaaatattt atgaatttat 8100 aaattatgat aaatattatc aaactgataa ggctttagcc actacaattg atggattttc 8160 aaggtatgta aatgagttaa aacctgattt aatcgtagta catggagata gaatcgagcc 8220 tttagcagca gctattgttg gagcattaaa taatatctta gtagcgcata ttgaaggcgg 8280 agagatttca ggaactattg acgatagctt acgccacgct atatcaaaac tagctcatat 8340 tcatttagta aatgatgagt ttgcaaaaag gcgtttaatg cagcttggag aagatgaaaa 8400 atctattttt atcataggtt cgcctgattt agaactttta aacgataata aaatttcact 8460 tagcgaagca aaaaaatatt atgatataaa ttatgaaaac tacgctttgc ttatgtttca 8520 tcctgttaca actgaaatta ctagcattaa aaatcaagca gataatttag taaaagcact 8580 gatacaaagt aataaaaatt atattgttat ttatccaaat aatgatttag gttttgaatt 8640 aatcttgcaa agctatgaag agcttaaaaa caatcctaga tttaagcttt ttccatcgct 8700 tagatttgag tattttataa ctttgttaaa aaatgctgat tttataatag gtaattcaag 8760 ttgcatttta aaagaggcct tatacttaaa aacagcaggg attttagttg gctcaagaca 8820 aaatggaaga cttggcaatg aaaatacact aaaagttaat gcaaatagtg atgaaatact 8880 aaaagctatt aacaccattc ataaaaaaca agatttattt agcactaagt tagagatttt 8940 agatagctca aaattatttt ttgaatattt attaagcgga gaatttttta aactcagcac 9000 acaaaaagtt tttaaggata taaaacatgc ttaaaaaaat catttcttta tataaaagat 9060 actcgatttc taaaaaattg gttttagata atgagcattt cattaaggaa aataaaaaca 9120 tctatggaaa aaaacataag ggcttttttg actttgatga aaaggctaag gatgtgaaat 9180 caccccttaa tccttgggga tttatcaggg ttaaaaatga agctttaacc ctaagagttt 9240 ctttagaaag tatactacct gctttacaaa gaggaattat agcttacaac gactgtgatg 9300 atgggagtga agagcttatt ttagaatttt gcaagcaata tcccaacttc attgctaaaa 9360 aatatcctta taaagtagat ctagaaaatc ctaaaaatga agaaaataaa ctttactctt 9420 attacaattg ggcagcatct tttataccct tagatgagtg gtttataaaa atcgatgtgg 9480 atcattacta cgatgccaag aagctttata agagttttta taggattgat caagaaaata 9540 aagccttatg ctacccaaga attaatttta taatcttaaa tggaaatatt tatgtgcaaa 9600 atagtggaaa ttatggattc ataggggggg gggatcaact cttgattaaa agaagaaata 9660 gtagctttat agaaagaagg gtttcaaaaa aaagccaatg gatagatcct aagggactta 9720 tagaagaact ctactccgag caacaagtct tatctcaagg agtgaaaata ctacaagctc 9780 ccctacttca gtggcatttt cctgccttaa aataccgccg aaacgattac caacaatatt 9840 tagatatctt gagtttagaa gaatttcagg cctttcatcg taagagcaaa gaggctaaaa 9900 aaatagactt tgccatgcta aaacgccctg taatcgagca aatattaaag aaatttcaag 9960 gagagataaa atgagcttag caataatccc tgctcgtggt ggctcaaagg gtattaaaaa 10020 taaaaatttg gttttattaa ataataaacc tttaatttat tacaccatta aagctgcact 10080 aaatgctaaa agcattagta aagttgttgt aagcagtgat agtgatgaaa ttttaaatta 10140 tgcaaaaagc caaaatgttg atattttaaa acgcccaatt agccttgcac aagatgatac 10200 tacaagcgat aaagtgcttt tacatgctct aaaattttac aaagattatg aagatgtagt 10260 ttttttacaa cccacttcgc cgctaagaac aaatattcat attgataaag cttttaatct 10320 ttataaaaat agcaatgcaa atgccctaat tagcgtaagc gaatgtgata ataaaattct 10380 aaaagccttt gtttgtaatg attatggcga tttagcaggg atttgtaatg atgaatatcc 10440 ttttatgcca aggcaaaaat tgcctaaaac ttatatgagc aatggtgcaa tttatatttt 10500 aaagataaaa gaatttttaa acaatcctag ctttttgcaa aacaaaacca agcatttttt 10560 aatggacgaa agctcaagtt tagatattga ctgtttagag gatttaaaaa aggttgaaca 10620 gatatggaaa aaataacctt aaaatgcaat aaaaatatat taaatttatt aaagcaatat 10680 aatatttata caaaaactta catagaaaat cctagaagat tttcaagact aaaaaccaaa 10740 gattttataa ccattccatt gaaaaacaat caattagaga gtgcggcggg gctggggata 10800 gaagaatatt gtgcttttaa atttagcaat atcttacatg aaatgggttc attttctttt 10860 agcggatctt ttctacctca ttatgcaaaa gttgaaaggt attgttcaat tgctgatggg 10920 gtttctatgt ttaactttca acaccctata gatagaatca gcactgcaag ttttacctat 10980 gaaacaaatc atagttttat taacgatgct tgccaaaatc acatcaacaa aacatttcct 11040 atagttaacc ataatccaag ctcatcaata acgcatttaa ttatacaaga tgatgtttgg 11100 ataggaaaag atgttttgct taaacagggt atcacacttg ggactggatg tgtcatagga 11160 caaagagctg tagttactaa agatgtacca ccttatgcta tagttgcagg aattccagcc 11220 aaaattatca aatatagatt tgatgaaaaa acaatagaaa gattattaaa aattcaatgg 11280 tggagatatc attttgctga tttttatgat attgatctta atttaaaaat aaaccaatat 11340 cttgacctac tagaagaaaa aatcataaaa aaatcaattt cctactataa tccaaataaa 11400 ctttatttta gagatatttt agaactaaaa tcaaaaaaaa tttttaatct attttaatct 11460 atttttcacc cctacttcct ctctctccaa aacttcaaat aatttctgat gaaattcatc 11520 atgtaaaaac tctttggaga gtctttttat gatttcatta cttttctttt tatcataata 11580 attttgattt aaaatttctt tatttttatt ctcatatctt ccatttggat taaattcgta 11640 atgataaatg caagttttaa aaacagctat tttctcgcaa aacataaaat aaacataaca 11700 aaaaagcaca tcttcgccgt aactcaaacg ctcatcgatt ttaacctttt caaatttaac 11760 cttttcaaaa ttttttaaga tgatatcttt tctaaaacac ttcgcccaaa ctgaccagca 11820 aaaatgcctt tgtttgctta agaattctaa aaattctttt tgattaaaaa ctccatcttg 11880 tttaaaacga taaaattgtt tggtttttac cctatgtaca aaggcatcaa aacaaagcaa 11940 atcaaaacct tttttcatct ctttaaacgc tatttcacaa gcaccaggtg tcaaaaaatc 12000 atcactatct aaaaacatta taaaatcaga actagaatgc aaaactccta aatttctact 12060 tgcaaaagtg cctaaatttt cttcattttg aaagattttt atccttggat cttttttagc 12120 aaattctaaa accatattta aactattatc tttactttta tcatcgataa tcaaaatttc 12180 aatatctttt aaagtctgat ttatacaact ttgcaaagct cttaagataa aatcacaaga 12240 attaaaaagc gggattatga tcgaaagttg tggcatattt ttcctaaatt ttgttaaaat 12300 aataaaaaca attctatcaa agtttaggaa atttatgaaa atttttatac atcttccca 12359 // |
|