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EBI DbfetchID D13329; SV 1; linear; genomic DNA; STD; PRO; 4539 BP. XX AC D13329; XX DT 20-JAN-1996 (Rel. 46, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 13) XX DE Escherichia coli uxuA, uxuB and uxuR genes for mannonate dehydratase, DE mannonate oxidoreductase and uxu regulon repressor, complete cds. XX KW glucuronate metabolism. XX OS Escherichia coli OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Escherichia. XX RN [1] RP 1-4539 RA Mizobuchi K.; RT ; RL Submitted (30-SEP-1992) to the EMBL/GenBank/DDBJ databases. RL Kiyoshi Mizobuchi, University of Tokyo, School of Science, Dept. of RL Biophysics and Biochemistry; 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan RL (Tel:03-2812-2111(ex.4406), Fax:03-5684-2394) XX RN [2] RP 1-4539 RA Mizobuchi K.; RT ; RL Unpublished. XX RN [3] RX DOI; 10.1007/BF00330526 RX PUBMED; 3083215. RA Blanco C., Ritzenthaler P., Kolb A.; RT "The regulatory region of the uxuAB operon in Escherichia coli K12"; RL Mol. Gen. Genet. 202(1):112-119(1986). XX CC Sequence updated (7-Feb-1997) by: Kiyoshi Mizobuchi XX FH Key Location/Qualifiers FH FT source 1..4539 FT /organism="Escherichia coli" FT /map="97 min" FT /strain="K12" FT /mol_type="genomic DNA" FT /clone_lib="Kohara's E. coli" FT /clone="1D6" FT /cell_line="W3110" FT /db_xref="taxon:562" FT misc_feature 465 FT /note="start site of uxuAB mRNA" FT CDS 580..1764 FT /codon_start=1 FT /transl_table=11 FT /gene="uxuA" FT /product="Mannonate dehydratase" FT /EC_number="4.2.1.8" FT /db_xref="GOA:P24215" FT /db_xref="InterPro:IPR013022" FT /db_xref="UniProtKB/Swiss-Prot:P24215" FT /protein_id="BAA02590.1" FT /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEI FT LKRKAIIEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNF FT MPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFA FT TMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPV FT AEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADN FT DLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAE FT GKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR" FT CDS 1845..3305 FT /codon_start=1 FT /transl_table=11 FT /gene="uxuB" FT /product="Mannonate oxidoreductase" FT /EC_number="1.1.1.57" FT /db_xref="GOA:P39160" FT /db_xref="HSSP:1LJ8" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/Swiss-Prot:P39160" FT /protein_id="BAA02591.1" FT /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHHL FT LESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALHPE FT IDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKSAIG FT YIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPC FT TMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFV FT ADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTVTNPAYRKAAFALMMQEQAPTLS FT MPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHL FT ALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLSGIFADDLP FT QNADFVGAVTAAYQQLCERGARECVAAL" FT misc_feature 3424 FT /note="start site of uxuR mRNA" FT CDS 3520..4293 FT /codon_start=1 FT /transl_table=11 FT /gene="uxuR" FT /product="uxu regulon repressor" FT /db_xref="GOA:P39161" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/Swiss-Prot:P39161" FT /protein_id="BAA02592.1" FT /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDV FT TRTVVREALIMLEIKGLVEVRRGAGIYVLDNSGSQNTDSPDANVCNDAGPFELLQARQL FT LESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATHNSM FT LVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQ FT HLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA" XX SQ Sequence 4539 BP; 1104 A; 1182 C; 1225 G; 1028 T; 0 other; gtcgaccatc aatttaccga tgaccgcacc gaacaccacg atgatagcca gttcccccag 60 cgtgttgccg aagcccgctt tcatagtgtg cagcagcgac atcaaatcca tgcccgccag 120 catcccgacg gacagcgccg ccaccaacaa agccaccatt gaattgattt tgaacttcaa 180 attcagtacc agcatcagac caatgccgaa taccacccag agaatgttaa gcacatgcat 240 aacgttttac cttacctggt tgaaccgttg ttattttggg cgatatgtta tgtaaattgg 300 tcaaccattg ttgcgatgaa tgtcacatcc tctgatcaat aaccatcgat taccctttgc 360 tgcaatttgc agcaacaacc atgagagtga aattcttgtg atgtggttaa ccaatttcag 420 aattcgggtt gacatgtctt accaaaaggt agaacttata cgccatctca tccgatgcaa 480 cgccacggct gcggtctggt tgttcatccg gatacctaaa caactccagg gttccgcgtc 540 tctttgctgt ggaacccact atgtgaaaga ggaaaaatca tggaacagac ctggcgctgg 600 tacggcccaa acgatccggt ttctttagct gatgtccgtc aggcgggcgc aactggcgtg 660 gttaccgcgc tgcaccatat cccgaacggc gaagtatggt ccgttgaaga gatcctcaaa 720 cgcaaggcga tcattgaaga cgcaggcctg gtgtggtctg tcgtagaaag cgtgccaatt 780 cacgaagata tcaaaaccca cactggcaac tatgagcagt ggatcgctaa ctatcagcag 840 actctgcgca acctggcgca gtgtggcatt cgcaccgtgt gctacaactt catgccggtg 900 ctcgactgga cccgtactga cctcgaatac gtgctgccag acggctccaa agctctgcgc 960 ttcgaccaga tcgaattcgc tgcattcgaa atgcatatcc tgaaacgccc aggcgcggaa 1020 gcggattaca ccgaagaaga aattgctcag gcagctgaac gcttcgccac tatgagcgat 1080 gaagacaaag cgcgtctgac ccgtaacatc attgctggtc ttccgggcgc ggaagaaggc 1140 tacaccctcg accagttccg taaacacctg gagctgtaca aagatatcga caaagcgaag 1200 ctgcgcgaaa actttgccgt cttcctgaaa gcgattattc cagttgctga agaagtcggc 1260 gtgcgtatgg ctgttcaccc ggacgatccg ccgcgcccga tcctcggcct gccgcgcatt 1320 gtttccacca ttgaagatat gcagtggatg gttgataccg taaacagcat ggcaaacggt 1380 tttaccatgt gcaccggttc ctacggcgtg cgtgctgaca acgatctggt tgatatgatc 1440 aagcagttcg gtccgcgtat ttacttcacc catctgcgct ccaccatgcg tgaagataac 1500 ccgaaaacct tccacgaagc ggcgcacctg aacggtgacg ttgatatgta cgaagtggtg 1560 aaagcgattg ttgaagaaga acaccgtcgt aaagcggaag gcaaagaaga cctgatcccg 1620 atgcgtccgg accacggtca tcagatgctg gacgacctga agaagaaaac caacccaggt 1680 tactccgcaa ttggtcgtct gaaaggcctg gccgaagttc gcggtgtcga actggcgatc 1740 cagcgcgctt tctttagccg ttaatatcca ccggcatggc tgcgcgccgt gccggttcct 1800 tcttccttgc cgtcactctt tgaagacgga ttctggagtt tacgatgact actattgttg 1860 acagcaatct gccggttgcc cgcccgtcat gggatcattc tcgtctggaa tcacgcattg 1920 tgcatctcgg ttgcggggcg tttcaccgcg cgcaccaggc gctgtatacc catcatctgc 1980 tggaaagcac cgacagcgac tggggcatct gcgaagttaa cctgatgcca ggcaacgacc 2040 gcgtgctgat cgaaaacctg aaaaaacagc aactgctgta caccgtagcg gaaaaaggcg 2100 cagagagcac cgagctgaaa attatcggtt cgatgaaaga agcgctgcat ccggaaatcg 2160 atggctgcga aggtattctc aacgcgatgg cgcgtccgca aacggcgatt gtctctctaa 2220 cggtcacgga aaaaggctac tgcgctgatg cggcaagcgg tcaactggat ctcaataacc 2280 cgctgatcaa gcacgatctg gaaaacccga ctgcgccgaa gtccgcgatt ggttacatcg 2340 tcgaagcgtt gcgtctgcgt cgtgaaaaag ggttgaaagc gtttacggtg atgtcctgcg 2400 ataacgtgcg tgaaaacggt catgtggcga aggtcgcggt actggggctg gctcaggcgc 2460 gtgacccgca gctggcggca tggattgaag aaaatgtcac cttcccgtgc accatggttg 2520 accgcatcgt tccggcggcg acgccagaaa ccttacagga aattgctgac cagctgggtg 2580 tttacgaccc gtgcgccatt gcctgcgaac cgttccgtca gtgggtgatt gaagataact 2640 tcgttaatgg tcgcccggat tgggataaag tgggcgcaca gttcgttgca gacgttgtgc 2700 cgttcgaaat gatgaagctg cgtatgctga acggcagcca ctcttttctg gcgtacctcg 2760 gttacctcgg cggctatgaa accattgccg acaccgtgac taacccggct tatcgcaaag 2820 cggcctttgc cctgatgatg caggaacaag cgccaacgct gtcgatgccg gaaggtacag 2880 acctgaacgc ctatgcgacg ctgctgatcg agcgtttcag caacccgtct ctgcgtcacc 2940 gtacctggca gattgcgatg gacggcagcc agaagttacc gcagcgtctg ctggacccgg 3000 tgcgtctgca cctgcaaaac ggcggcagct ggcgtcacct ggcgctgggc gtggctggct 3060 ggatgcgtta cacccagggc gtggatgagc agggtaatgc cattgacgtg gtcgacccga 3120 tgctggcgga gttccagaag atcaacgcgc agtatcaggg cgcagaccgc gtgaaagcgc 3180 tgctgggcct gagcggtatt tttgccgatg atctgccgca gaatgccgac tttgttggcg 3240 cagtgacggc ggcatatcag cagctgtgcg aacgcggtgc gcgcgagtgt gtggctgcgc 3300 tgtaactaac tgattaccct acagacttac tggtcaatca aactgatatt tggttgacca 3360 gttttcgttt ttttgcccac ctgtacgtgc caacttccag tgctaatggt atagtttgag 3420 attaacgggg gccgtaaaat tgcccgttgt aggccggata aggcgttcac gccgcatccg 3480 gcaaaaattt gattaaccgc acctaacgga cacaacacca tgaaatctgc cacctctgcg 3540 caaagacctt accaggaagt cggggcgatg atccgcgatc tgatcataaa gacgccgtac 3600 aatcctggcg aacggctgcc gccggagcgt gaaattgcag aaatgcttga tgtcacgcgg 3660 acggtggtac gtgaagcgct gatcatgctg gagatcaaag ggctggtgga agtacgccgg 3720 ggtgccggta tctatgttct tgataactca ggcagccaga acacagacag tccggatgcc 3780 aacgtctgca acgatgccgg tccttttgag ctgttacagg cgcggcagtt attggagagc 3840 aacatcgccg agtttgccgc tttgcaggct acccgcgaag atatcgtcaa aatgcgtcag 3900 gcattgcaac tggaagagcg tgaactggct tccagtgcgc cgggcagcag cgaaagcggt 3960 gacatgcagt tccatctcgc tattgccgaa gcaacgcata acagcatgct ggtggagctg 4020 ttccgtcagt cctggcagtg gcgggaaaac aatccaatgt ggatccagtt gcacagccat 4080 ctggatgaca gcctgtatcg caaagagtgg ttgggcgatc acaaacagat cctcgccgcg 4140 ttaatcaaaa aagatgcccg agcggcgaag ctggcaatgt ggcagcatct ggaaaacgtt 4200 aagcaacgtc tgctggaatt ctcgaacgtt gacgatattt attttgatgg ctatctgttt 4260 gattcatggc cgctggataa agtcgacgcc tgacttatta taataagcgc aagggtaaac 4320 gttccttgcg ctttcttaaa ttaagaagtc gcaatgagta ttactttgta aattgcaggg 4380 tattgtttag ctatctgtat aacctgaatg ttagtactca ttcttcctgg tagttattta 4440 ccaatataat tccattcacc attttttaat tcaaacagtt ctggaagaga tgacggttgc 4500 agagtcatac gtttgagtgg tgcattttca tcacccggg 4539 // |
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