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EBI DbfetchID D00647; SV 1; linear; genomic DNA; STD; VRL; 7933 BP. XX AC D00647; XX DT 27-MAR-1991 (Rel. 27, Created) DT 07-DEC-2007 (Rel. 94, Last updated, Version 6) XX DE Bovine leukemia virus genomic DNA, complete sequence. XX KW env gene; gag gene; gp30 transmembrane protein; gp51 surface glycoprotein; KW pol gene. XX OS Bovine leukemia virus OC Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; OC Deltaretrovirus. XX RN [1] RP 1-7933 RX PUBMED; 2167927. RA Coulston J., Naif H., Brandon R., Kumar S., Khan S., Daniel R.C., RA Lavin M.F.; RT "Molecular cloning and sequencing of an Australian isolate of proviral RT leukemia virus DNA: Comparison with other isolates"; RL J. Gen. Virol. 71:1737-1746(1990). XX DR RFAM; RF00192; BLV_package. XX CC These data kindly submitted in computer readable form by: CC Martin F. Lavin CC Queensland Institute of Medical Research CC Bramston Terrace CC Herston Qld 4006 CC Australia XX FH Key Location/Qualifiers FH FT source 1..7933 FT /organism="Bovine leukemia virus" FT /isolate="Australian isolate" FT /mol_type="genomic DNA" FT /clone="pBLV-A1" FT /note="proviral DNA" FT /db_xref="taxon:11901" FT LTR 1..531 FT /note="5' LTR" FT CDS 629..1807 FT /codon_start=1 FT /gene="gag" FT /db_xref="GOA:P25058" FT /db_xref="HSSP:1QRJ" FT /db_xref="InterPro:IPR001878" FT /db_xref="UniProtKB/Swiss-Prot:P25058" FT /protein_id="BAA00543.1" FT /translation="MGNSPSYNPPAGISPSDWLNLLQSAQRLNPRPSPSDFTDLKNYIH FT WFHKTQKKPWTFTSGGPASCPPGKFGRVPLVLATLNEVLSNDEGAPGASAPEEQPPPYD FT PPAVLPIISEGNRNRHRAWALRELQDIKKEIENKAPGSQVWIQTLRLAILQADPTPADL FT EQLCQYIASPVDQTAHMTSLTAAIAAEAAIPSRVLIPKMGTLTQQSAQPNAGDLRSQYQ FT NLWLQAGRISLLVLQVQPWSTIVQGPAESYVEFVNRLQISLADNLPDGVPKEPIIDSLS FT YANANKECQQILQGRGLVAAPVGQKLQACAHWAPKTKQPAILVHTPGPKMPGPRQPAPK FT RPPPGPCYRCLKEGHWARDCPTKTTGPPPGPCPICKDPSHWKRDCPTLKSKN" FT CDS <2318..4876 FT /codon_start=1 FT /gene="pol" FT /note="putative: This is the largest reading frame in the FT pol gene region." FT /db_xref="GOA:P25059" FT /db_xref="HSSP:1C1A" FT /db_xref="InterPro:IPR010661" FT /db_xref="UniProtKB/Swiss-Prot:P25059" FT /protein_id="BAA00544.1" FT /translation="GTSIPFKLERLQALQDLVHRSLEAGYISPWDGPGNNPVFPVRKPN FT GAWRFVHDLRVTNALTKPIPALSPGPPDLTAIPTHLPHIICLDLKDAFFQIPVEDRFRS FT YFAFTLPTPGGLQPHRRFAWRVLPQGFINSPALFERALQEPLRQVSAAFSQSLLVSYMD FT DILYVSPTEEQRLQCYQTMAAHLRDLGFQVASEKTRQTPSPVPFLGQMVHERMVTYQSL FT PTLQISSPISLHQLQTVLGDLQWVSRGTPTTRRPLQLLYSSLKGIDDPRAIIHLSPEQQ FT QGIAELRQALSHNARSRYNEQEPLLAYVHLTRAGSTLVLFQKGAQFPLAYFQTPLTDNQ FT ASPWGLLLLLGCQYLQAQALSSYAKTILKYYHNLPKTSLDNWIQSSEDPRVQELLQLWP FT QISSQGIQPPGPWKTLVTRAEVFLTPQFSPEPIPAALCLFSDGAARRGAYCLWKDHLLD FT FQAVPAPESAQKGELAGLLAGLAAAPPEPLNIWVDSKYLYSLLRTLVLGAWLQPDPVPS FT YALLYKSLLRHPAIFVGHVRSHSSASHPIASLNNYVDQLLPLETPEQWHKLTHCNSRAL FT SRWPNPRISAWDPRSPATLCETCQRLNPTGGGKMRTIQRGWAPNHIWQADITHYKYKQF FT TYALHVFVDTYSGATHASAKRGLTTQTTIEGLLEAIVHLGRPKKLNTDQGANYTSKTFV FT RFCQQFGISLSHHVPYNPTSSGLVERTNGLLKLLLSKYHLDEPHLPMTQALSRALWTHN FT QINLLPILKTRWELHHSPPLAVISEGGETPKGSDKLFLYKLPGQNNRRWLGPLPALVEA FT SGGALLATNPPVWVPWRLLKAFKCLKNDGPEDAPNRSSDG" FT CDS 4822..6369 FT /codon_start=1 FT /gene="env" FT /product="precursor of env protein" FT /db_xref="GOA:P25057" FT /db_xref="HSSP:1MOF" FT /db_xref="InterPro:IPR018154" FT /db_xref="UniProtKB/Swiss-Prot:P25057" FT /protein_id="BAA00545.1" FT /translation="MPKERRSRRRPEPIIRWVSLTLTLLALCQPIQTWRCSLSLGNQQW FT MTAYNQEAKFSISIDQILEAHNQSPFCAKSPRYTLDSVNGYPKIYWPPPQGRRRFGARA FT MVTYDCEPRCPYVGADRFDCPHWDNASQADQGSFYVNHQILFLHLKQCHGIFTLTWEIW FT GYDPLITFSLHKIPDPPQPDFPQLNSDWVPSVRSWALLLNQTARAFPDCAICWEPSPPW FT APEILVYNKTISSSGPGLALPDAQIFWVNTSSFNTTQGWHHPSQRLLFNVSQGNALLLP FT PISLVNLSTASSAPPTRVRRSPVAALTLGLALSVGLTGIKVAVSALSHQRLTSLIHVLE FT QDQQRLITAINQTHYNLLNVASVVAQNRRGLDWLYIRLGFQSLCPTINEPCCFLRIQND FT SIIRLGDLQPLSQRVSTDWQWPWNWDLGLTAWVRETIHSVLSLFLLALLLLFLAPCLIK FT CLTSRLSKLLRQAPHFPEISFPPKPDSDYQALLPSAPEIYSHLSPTKPDYINLRPCP" FT sig_peptide 4822..4920 FT /note="signal peptide of env protein" FT mat_peptide 4921..5724 FT /product="gp51 surface glycoprotein (env)" FT mat_peptide 5725..6366 FT /product="gp30 transmembrane protein (env)" XX SQ Sequence 7933 BP; 1759 A; 2632 C; 1673 G; 1869 T; 0 other; tgtatgaaag atcatgccga cctaggagcc gccaccgccc cgcgcgaacc agacagagac 60 gtcagctgcc agaaaagctg gtgacggcag ctggtggcta gaatccccgc acctccccaa 120 cttccccttt cccgagaaat ccacaccctg agctgctgac ctcacctgct gataaattaa 180 taaaatgccg gccctgtcga gttagcggca ccagaagcgc tcttctcctg agaccctcgt 240 gctcagctct cggtcctgag ctctcttgct cccgagacct tctggtcggc tatccggcag 300 gcggcaggta aggcaagcac ggtttggagg gtggttctcg gctgagacca ccgcgagctc 360 tatctccggt ccttgaccgt ctccacgtgg actctctctc ttgcctcctg accccgcgct 420 ccaagggcgt ctggcttgca cccgcgttcg tttcctgtct tactttctgt ttctcgcggc 480 ccgcgctctc tccttcggcg ccctctagcg gccaggggag accggcaaac aattgggggc 540 tcgtccggga ttgatcaccc cggaacccta aaacttctct ggacccaccc cctcggcggc 600 gtcttgggtc tttccttcaa atcatatcat gggaaactcc ccctcctata acccccccgc 660 tggcatctcc ccctcagact ggctcaacct cctgcaaagc gcgcaaaggc tcaatccacg 720 accctccccc agcgatttta ccgatttaaa aaattacatc cattggtttc ataagaccca 780 gaaaaaacca tggactttca cttctggtgg ccccgcctca tgcccacccg ggaaattcgg 840 ccgagttccc cttgtcttgg ccaccctaaa cgaagtgctc tcaaacgatg agggcgcccc 900 gggtgcatcg gccccagaag aacaaccccc cccttatgac cctcccgctg ttttaccaat 960 catatctgaa gggaatcgca accgccaccg cgcttgggca ctccgagaat tacaagatat 1020 taaaaaggag attgaaaata aggcaccggg gtcgcaagta tggatacaaa cgctacgact 1080 tgcaatcctg caggccgacc ctacccctgc tgacctagaa cagctttgcc aatatattgc 1140 ttccccggtc gaccaaacgg cccacatgac cagcctaacg gcggcaatag ccgctgaagc 1200 ggcaataccc tccagggttt taatccccaa aatgggaacc ctgacccaac aatcagctca 1260 gcccaacgcc ggagatctta ggagtcaata tcaaaacctc tggcttcagg ctggaagaat 1320 ctccctactc gtccttcagg tacaaccctg gtccaccatc gtccagggcc ccgccgagag 1380 ctatgtagag tttgtcaacc ggttacaaat ttcattagct gacaaccttc ccgacggagt 1440 ccctaaagaa cccattattg actcccttag ttatgcaaat gccaacaaag aatgccaaca 1500 aattttgcag gggcggggct tagtggccgc cccggtggga caaaaactgc aggcttgtgc 1560 acactgggcc cccaagacta aacagcctgc aatcctcgtc cacaccccag ggcccaagat 1620 gcccgggcct cggcaaccgg cccccaaaag gccccccccg ggaccatgct atcgatgcct 1680 caaagaaggc cattgggccc gggactgtcc caccaaaacc accggccccc ctccgggacc 1740 ttgtcccata tgtaaagatc cttcccattg gaaacgagac tgtccaaccc tcaaatcaaa 1800 aaactaatag aggggggacc tagcgccccc caaatcataa cacctataac agattctctc 1860 agtgaggccg aattagaatg cttactttct attcctctgg ctcgcagccg tccctccgtg 1920 gctgtatacc tgtctggccc ctggctgcag ccctctcaaa atcaagccct catgctcgtg 1980 gacaccgggg ctgaaaatac ggtcctccca caaaattggc tggttcgaga ttacccacgg 2040 acccccgccg cggtactcgg agcgggagga atctcccgga acagatacaa ttggctacaa 2100 ggccctctga ccctggctct aaaaccagag ggtcccttta tcaccatccc aaaaatttta 2160 gttgacacct tcgataaatg gcaaatttta ggacgggacg tctctcccgc ctacaggctt 2220 ctatctccat acctgaggaa gtacaccccc ctgtggtagg cgtcttagat gcccccccga 2280 gccacattgg attagaacat ttgccccccc cacctgaggt acctcaattc cctttaaact 2340 agaacgcctc caggcccttc aagacctggt ccatcgctct ctggaggcag gttatatctc 2400 cccctgggac gggccaggca ataatccagt cttcccggta cggaaaccaa atggtgcctg 2460 gaggtttgtg catgatctac gagttacaaa tgctcttaca aagcccatcc cggcactctc 2520 ccccggaccg ccagacctta ccgctatccc cacacacctt ccacatatca tttgtttaga 2580 tctcaaagat gccttcttcc agattccagt cgaagaccgc ttccgctcct actttgcttt 2640 taccctccct acccccgggg gacttcaacc tcatagacgc ttcgcctggc gggtcctacc 2700 tcaaggcttc attaacagcc cagctctttt cgaacgggca cttcaggaac cccttcgcca 2760 agtttccgcc gccttttccc agtctcttct ggtgtcctat atggacgata tcctttacgt 2820 ttcgcctaca gaggaacaac ggttacaatg ttatcaaact atggctgccc acctccggga 2880 cctagggttt caggtggcgt ctgaaaagac tcgccagacg ccttcgcctg tccctttctt 2940 gggacaaatg gtccatgagc ggatggtcac ctaccagtcc ctacctacct tgcagatctc 3000 atccccaatt tctcttcacc aattacagac ggtcttggga gacctccaat gggtctctag 3060 gggcacaccc actacccgcc ggcccctgca acttctatac tcttctctta aaggcatcga 3120 tgacccaagg gccatcatcc acctttcccc ggaacagcag cagggcattg cagagcttcg 3180 acaagccctg tcccataacg caagatccag atataacgag caggaacccc tgctggccta 3240 cgtacacctc acccgggcgg ggtccaccct ggtactcttc cagaagggcg ctcaatttcc 3300 cctggcctac tttcagaccc ccttgactga caaccaagcc tcaccttggg gcctccttct 3360 cctgctggga tgccaatatc tgcaggctca ggccttaagc tcctatgcca agaccatact 3420 caaatactat cacaatcttc ctaaaacctc tctagacaat tggatccaat catctgagga 3480 ccctcgagtt caggagttgt tgcaattgtg gccccagatt tcctctcagg gaatacagcc 3540 cccgggcccc tggaagacct tagtcaccag ggcagaggtt tttttgacgc cccagttctc 3600 ccctgaaccg atccctgcgg ccctttgcct ctttagtgac ggggctgcaa gacgaggagc 3660 atattgctta tggaaagacc accttttgga ctttcaggcc gttccagctc cagagtccgc 3720 ccaaaaggga gaactagcag gtcttttggc gggcttagca gccgccccgc ctgaaccttt 3780 aaatatatgg gtagattcca aatacctgta ctccttgctc agaaccctag ttctaggagc 3840 ttggcttcaa cctgaccccg taccctctta tgccctccta tataaaagcc tcctccgaca 3900 tccagcaatc tttgttggtc atgttcggag ccactcttca gcatcccacc ctattgcttc 3960 cctgaacaat tatgtagatc aactgcttcc cttagaaact ccagagcaat ggcataagct 4020 cacccactgc aactctcggg ccttgtctcg atggccgaac ccacgtattt ctgcctggga 4080 tccccgttcc cccgctacgc tgtgtgaaac ctgtcaaagg ctcaacccaa ctggaggcgg 4140 aaagatgcgg actattcaga gagggtgggc cccaaatcat atctggcagg ccgatataac 4200 tcattataaa tacaaacagt tcacctacgc tttgcacgtg tttgtagata cttactctgg 4260 agctactcat gcctcagcaa agcgagggct caccactcaa acgaccattg agggccttct 4320 tgaggccata gtgcatctag gtcgtccaaa aaagctaaac accgaccaag gtgctaacta 4380 cacctccaaa acctttgtca ggttttgcca gcagttcgga atttcccttt ctcatcatgt 4440 tccctacaac cccacaagtt cagggttagt ggaacggaca aatggactgc tcaaacttct 4500 tttgtctaaa tatcacttag acgaacccca ccttcccatg actcaggccc tttctcgagc 4560 cctctggact cacaatcaga ttaacctcct accaattcta aagaccagat gggagctaca 4620 ccattcaccc ccacttgctg tcatttcaga gggcggagaa acacccaagg gctctgataa 4680 actctttttg tacaagctcc ccgggcaaaa caatcgtcgg tggctaggac cactcccggc 4740 cctagtcgaa gcctcgggag gcgctctcct ggctaccaac ccccccgtgt gggttccctg 4800 gcgtttgctg aaggccttca aatgcctaaa gaacgacggt cccgaagacg ccccgaaccg 4860 atcatcagat gggtaagtct cactctcact ctcctcgctc tctgtcagcc catccagact 4920 tggagatgct ccctgtccct aggaaatcaa caatggatga cagcatataa ccaagaggca 4980 aaattttcca tctccattga ccaaatacta gaggctcata atcagtcacc tttctgtgcc 5040 aagtctccca gatacacctt ggactctgta aatggctatc ctaagatcta ctggcccccc 5100 ccacaagggc ggcgccggtt tggagccagg gccatggtca catatgattg cgagccccga 5160 tgcccttatg tgggggcaga tcgcttcgac tgcccccact gggacaatgc ctcccaggcc 5220 gatcagggat ccttttatgt caatcatcag attttattcc tgcatctcaa acaatgtcat 5280 ggaattttca ctctaacctg ggagatatgg ggatatgatc ccctgatcac cttttcttta 5340 cataagatcc ctgatccccc tcaacccgac tttccccagt tgaacagtga ctgggttccc 5400 tctgtcagat catgggccct gcttttaaat caaacagcac gggccttccc agactgtgct 5460 atatgttggg aaccttcccc tccctgggct cccgaaatat tagtatataa caaaaccatc 5520 tccagctctg gacccggcct cgccctcccg gacgcccaaa tcttctgggt caacacgtcc 5580 tcgtttaaca ccacccaagg atggcaccac ccttcccaga ggttgttgtt caatgtttct 5640 caaggcaacg ccttgttatt acctcctatc tccctggtta atctctctac ggcttcctcc 5700 gcccctccta cccgggtcag gcgtagtcct gtcgcggccc tgaccttagg tctagccctg 5760 tcagtggggc tcactggaat taaagtagcc gtgtctgccc ttagccatca gagactcacc 5820 tccctgatcc acgttctgga acaagatcag caacgcttga ttacagcaat taaccagacc 5880 cactataatt tgcttaatgt ggcctctgtg gtcgcccaga accgacgggg gcttgattgg 5940 ttgtacatcc ggctgggttt tcaaagccta tgtcccacaa tcaatgaacc ttgctgtttc 6000 ctgcgcattc aaaacgactc catcatccgc ctcggtgatc tccagcctct ctcgcaaaga 6060 gtctctacag actggcagtg gccctggaat tgggatctgg gactcactgc ctgggtgcga 6120 gaaaccattc attccgttct aagcctgttc ctattagccc ttcttttgct cttcttggcc 6180 ccctgcctga taaaatgctt gacctctcgc ctttcaaagc tcctccggca ggctccccac 6240 ttccctgaga tctccttccc ccctaaaccc gattctgatt atcaggcctt gctaccgtca 6300 gcaccagaga tctactctca cctctccccc accaaacccg attacatcaa ccttcgaccc 6360 tgcccttgac acccccgtgt ttcacgcacc ctcaggctgt ggtggggcac tggcttagtg 6420 gaatagtcag tgtaccatca caagcctctt cttgctgcca gcaccgagtt cgaacacagc 6480 cctaccctga gcctctctga gtacatgact gagtgtagcg cagagaggtt gtcgcttctg 6540 cgtgtcactc agtcattttt tatagccgat tggggttcgc gccctcccat tgcctgtgac 6600 acggttaaga cctctctcac ttctgcttca ccatccccct gccagcgttg gtctagtgga 6660 aagaactaac gctgacgggg gcgatttctt gcagctgtgc taagcgagag gctctggtgc 6720 tggggataag atgcggcccc tagcaccacc gtctctgcgc cttttgggtt cgaatcttcc 6780 ccatgcagct tccgcttttt acgccctgtt gcacaccctt tctagagata cctgaaaatc 6840 tcagctcgca ccccaaggaa ggttgtggct cagaggttaa aatagctcga gccgcaacct 6900 ccctttcttt ttattccacc ctcgcaaggc cccgggttct gagcccccta acggaggttt 6960 aaaatttcct ctactagagg atgctcggga ggaagtcacg tcaatatctc ttcgaaaagg 7020 tcctgatgaa catcttccca tgtaacaagc cccaacagag acattccagc cacatccagc 7080 agcattcggg ccgccttctc taacagtgcc cataaagtct cttccgtttc cacaacgcct 7140 gcctctgcat cttctatttc cacctcggca ccgactcccc cgccgagccc ctcgagctct 7200 tcgggatcca ttacctgata acgacaaaat tatttcttgt cttttaagca agtgttgttg 7260 gttgggggcc ccactctctg catgcctgcc cggccctggt tttgtccaat gatgtcacca 7320 tcgatgcctg gtgccccctc tgcgggcccc atgaacgact ccaattcgag aggatcgaca 7380 ccacgctcac ctgcgagacc caccgtatca cctggaccgc cgatggacga cctttcggcc 7440 tcaatggaac gttgttccct cgactgcatg tctccagaga cccgccccca agggccccga 7500 cgactctgga tcaactgccc ccttccggcc gttcgcgctc agcccggccc ggtttcactt 7560 tcccccttcg agcagtcccc cttccagccc taccaatgcc aattgccctc ggcctctagc 7620 gatggttccc ccatcatcgg gcacggcctt cttccctgga acaacttagt aacgcacccc 7680 gtcctcggaa aagtccttat attaaatcag atggcaaatt tctccttact cccctccttc 7740 gataccctca ttgtagaccc cctccggctg tccgtctttg ccccggacca ctaggggagc 7800 catacgttat ctctccaccc ttttgacgct atgcccagct acttgtatcc tacccctaga 7860 cgagcccttc tctcctaatg tccccatatg ccgctttccc cgggactcca atgaaccccc 7920 cctttcagaa ttc 7933 // |
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