spacer
spacer
EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   D00646; SV 1; linear; mRNA; STD; VRT; 1902 BP.
XX
AC   D00646;
XX
DT   01-JUN-1991 (Rel. 28, Created)
DT   18-APR-2005 (Rel. 83, Last updated, Version 5)
XX
DE   Xenopus laevis mRNA for RCC1 protein, partial cds.
XX
KW   RCC1; regulator for chromosome condensation.
XX
OS   Xenopus laevis (African clawed frog)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Xenopus.
XX
RN   [1]
RP   1-1902
RX   PUBMED; 2361953.
RA   Nishitani H., Kobayashi H., Ohtsubo M., Nishimoto T.;
RT   "Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene:
RT   complementation of tsBN2 mutation and identification of the product";
RL   J. Biochem. 107(2):228-235(1990).
XX
CC   The RCC1 protein was suggested to regulate the onset of chromosome
CC   condensation in the eukaryote from amphibian to mammalian cells.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1902
FT                   /organism="Xenopus laevis"
FT                   /mol_type="mRNA"
FT                   /clone_lib="libraries provided by D. Melton and by B. Kay"
FT                   /clone="lambda 0-23"
FT                   /note="103 bp upstream of PvuII site"
FT                   /db_xref="taxon:8355"
FT   CDS             <1..1219
FT                   /codon_start=2
FT                   /standard_name="regulator for chromosome condensation"
FT                   /product="RCC1 protein"
FT                   /db_xref="GOA:P25183"
FT                   /db_xref="HSSP:1I2M"
FT                   /db_xref="InterPro:IPR009091"
FT                   /db_xref="UniProtKB/Swiss-Prot:P25183"
FT                   /protein_id="BAA00542.1"
FT                   /translation="SNGTSDVKKTKVTHPSHGTVGGQVLTLGQGDVGQLGLGEDIMERK
FT                   KPALVTLTEDIVQAAAGGMHTVCLGASGSIYTFGCNDEGALGRDTSEEGSEMQPGKVEL
FT                   AEKVVQVSAGDSHTAALTEDGRVFVFGSFRDNNGVIGLLEPMKKSMVPVQVQINTPVIK
FT                   IASGNDHLVLLTVDGDLYTSGCGEQGQLGRVPERFTNRGGRKGLERLLVPQCIHLKAKG
FT                   SGRVHFQDVFCGAYFTFAVSQEGHVYGFGLSNYHQLGTKNTQACYAPQNLTSFKNSTKS
FT                   WIGFSGGQHHTVCVDSEGKAYSLGRAEYGRLGLGENAEEQSEPTPIPDLPKINSVASGA
FT                   SVSYAVSTDGCVFAWGMGTNLQLGTGEEEDVWSPEQMTGKHLEDREVLSVSSGGQHTVL
FT                   LVRKRS"
FT   polyA_signal    1885..1890
FT   polyA_site      1902
FT                   /note="10 a nucleotides"
XX
SQ   Sequence 1902 BP; 505 A; 390 C; 442 G; 565 T; 0 other;
     aagcaatgga acttccgatg ttaagaaaac aaaagtcact catccttcac atggcacagt        60
     tgggggccag gtattaaccc ttgggcaggg agatgtaggg cagctgggtc ttggagaaga       120
     cataatggag aggaaaaaac ctgccctggt tacccttact gaggacatag tacaagcagc       180
     agctggagga atgcacactg tgtgccttgg agcatctgga agtatatata cctttgggtg       240
     caatgatgag ggtgcactgg gtcgtgatac ctcagaagaa ggatcggaaa tgcagcctgg       300
     caaggtggag cttgcagaaa aggtggtgca ggtgtcggca ggagacagtc atacagctgc       360
     tctgacagaa gatggcagag tgtttgtctt tggatcattc agggataata acggtgttat       420
     tggattactg gaacctatga agaaaagcat ggtgcctgtt caagtgcaaa taaacacgcc       480
     agtaattaaa atagcctctg gtaatgatca tcttgtgttg cttaccgtgg atggtgacct       540
     atacacgtca ggatgcggag agcagggtca gttgggaaga gttccagaga gatttaccaa       600
     tcgtggaggg cgcaaagggc tagaaagact gttggttcca caatgtatcc acctaaaggc       660
     aaagggaagc gggcgtgtgc atttccagga tgtgttttgt ggcgcatact tcacctttgc       720
     ggtgtcccaa gaaggccatg tatatggctt tggtctttca aattatcatc agcttggaac       780
     aaaaaacact caggcctgct atgcaccaca gaacttaaca tcatttaaaa actccaccaa       840
     gtcctggatc ggtttctctg gaggacaaca tcacaccgtt tgtgtggact ctgaagggaa       900
     ggcttatagt cttggccgtg cagaatatgg cagacttggt cttggggaaa atgcagaaga       960
     acagagtgag cccaccccaa ttcctgactt acctaagatc aattctgttg catctggagc      1020
     atctgtcagc tatgctgtgt ctactgatgg ttgtgtcttt gcctggggca tgggtacaaa      1080
     ccttcagcta ggtactggtg aagaagagga tgtctggagt cccgagcaga tgactgggaa      1140
     acaccttgaa gaccgggagg tcctgtctgt atccagtgga ggtcagcaca ctgtccttct      1200
     agtgcgaaaa agaagctgac cgcgtcttct acaaaaaaaa cactcattga ccaagtcagc      1260
     ctgagtggag tgtagcaaca atgctgcagt cctccctttt gcacaacata gaaacatttt      1320
     aattggtcca taataaataa cacacttttg tggagctgcc cctcctggca ccattttgtt      1380
     tgtgtcatcc aacataacca aaaatgtttc tgactttacc ctctgcatga ctcttgtttt      1440
     atttcagtct gtttctcttt tttttttttt tttttttcct atttctattt tgcggaacca      1500
     tctcaccctc actttgtggg gtttgatttt tagcttcctt aagatctgtt ttctgtttgg      1560
     tgagcattta ccttacatct gtttggtcta taaaattgaa tttacagacc aagcactcct      1620
     gcttttatct cttccctttc ttgctagctc actgcctttc cccaacctct tatcaggggt      1680
     tcattataac tgttggataa ggtttttact tttaatatcc catcccattc caaaaaaaaa      1740
     aattgcttta tttttttaaa ttgagctgtg attttctgta cagacaggca tgtattactc      1800
     tgggaaatct gtttccggtt cccgtaaaaa aaaaaatcta ttttgatttt atggggacat      1860
     aaaacacctt ttatctgtct ttggaataaa tttgtttttc at                         1902
//
spacer
spacer