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EBI DbfetchID BX251410; SV 1; linear; genomic DNA; STD; PRO; 324050 BP. XX AC BX251410; XX DT 17-FEB-2003 (Rel. 74, Created) DT 30-NOV-2006 (Rel. 89, Last updated, Version 3) XX DE Tropheryma whipplei TW08/27, complete genome; segment 1/3 XX KW complete genome. XX OS Tropheryma whipplei TW08/27 OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Micrococcineae; Tropheryma. XX RN [1] RP 1-324050 RX DOI; 10.1016/S0140-6736(03)12597-4 RX PUBMED; 12606174. RA Bentley S.D., Maiwald M., Murphy L.D., Pallen M.J., Yeats C.A., Dover L., RA Norbertczak H.T., Besra G.S., Quail M.A., Harris D.E., von Herbay A., RA Goble A., Rutter S., Squares R., Squares S., Barrell B.G., Parkhill J., RA Relman D.A.; RT "Sequencing and analysis of the genome of the Whipple's disease bacterium RT Tropheryma whipplei"; RL Lancet 361(9358):637-644(2003). XX RN [2] RP 1-324050 RA Bentley S.D.; RT ; RL Submitted (10-FEB-2003) to the EMBL/GenBank/DDBJ databases. RL Submitted on behalf of the Pathogen Sequencing Unit, Sanger Institute, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL sdb@sanger.ac.uk XX DR EMBL-CON; BX072543. DR RFAM; RF00005; tRNA. XX FH Key Location/Qualifiers FH FT source 1..324050 FT /organism="Tropheryma whipplei TW08/27" FT /strain="TW08/27" FT /mol_type="genomic DNA" FT /db_xref="taxon:218496" FT CDS 1..1437 FT /transl_table=11 FT /gene="dnaA" FT /locus_tag="TW001" FT /product="chromosomal replication initiator protein DnaA" FT /note="Similar to Streptomyces coelicolor chromosomal FT replication initiator protein DnaA or SCO3879 or SCH18.16c FT SWALL:DNAA_STRCO (SWALL:P27902) (656 aa) fasta scores: E(): FT 3.8e-67, 53.02% id in 347 aa, and to Micrococcus luteus FT chromosomal replication initiator protein DnaA FT SWALL:DNAA_MICLU (SWALL:P21173) (515 aa) fasta scores: E(): FT 1.1e-64, 42.17% id in 505 aa" FT /db_xref="GOA:Q83NZ5" FT /db_xref="HSSP:1L8Q" FT /db_xref="InterPro:IPR013317" FT /db_xref="UniProtKB/Swiss-Prot:Q83NZ5" FT /protein_id="CAD66693.1" FT /translation="MNKTLNPQEVWIKAVRNLEGFFSSPRVIGYLKKASPSIEGESLII FT TFPNSHLASVMDDIEVYDATKKTILDSYPSIKEIKITISPDVLEKEITEEINDLVQSME FT EEDFALIDHTKPVIPNFFDQNTRVNFGGGPNNHHPTTGVNPRFTFDNFVVGKSNELARA FT ASISAAERPGKSFNPLFIYGDSGVGKTHLLHSIGNYAKFLFPSLRIKYVSSEDFTNDFI FT NSISSGTSQKFQEKYRQIDILMVDDIQFLQKKQETQESFFHTFNSLHNSSRQLVISSDL FT PPKQLMGFEDRMRSRFECGLVCDIQKPDLETRIAILQKKCQNEKKEVSMEILTYIASCF FT SSSVRELEGALLRIFALASFNKEEINMTLAQKVLEDLGAQRGDKIDPIEIIEITAKHYD FT LAASDLCGNSRVANISIARQIAMYLCRELTDVSLPKLGYIFGRDHSTIIYATRRISDLI FT GKDRKTFSDIYKLTQFILRR" FT misc_feature 427..1360 FT /note="Bacterial dnaA protein Score = 573.7 E-value = FT 8.2e-170" FT misc_feature 502..525 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 535..576 FT /note="PS00675 Sigma-54 interaction domain ATP-binding FT region A signature." FT misc_feature 547..570 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 1306..1362 FT /note="PS01008 DnaA protein signature." FT CDS 1767..2900 FT /transl_table=11 FT /gene="dnaN" FT /locus_tag="TW002" FT /product="DNA polymerase III, beta chain" FT /EC_number="2.7.7.7" FT /note="Similar to Streptomyces coelicolor DNA polymerase FT III, beta chain DnaN or SCO3878 or SCH18.15c FT SWALL:DP3B_STRCO (SWALL:P27903) (376 aa) fasta scores: E(): FT 7.5e-42, 35.46% id in 375 aa" FT /db_xref="GOA:Q83IG6" FT /db_xref="InterPro:IPR001001" FT /db_xref="UniProtKB/TrEMBL:Q83IG6" FT /protein_id="CAD66694.1" FT /translation="MKLIVDRGLLSSSVNFVTRMIPARPPSPILSGMLIEAKNEKVTLS FT TFNYETSAKVEFSANVIEGGKVLVPGTLISSISQKLPDEPVEISKEDEKISLTCGPVNY FT ILNLMPIAEYPPLPNLENAEQYRIPSEDFVKSVSQVTTSAAKDDISAVITGINLRLSNE FT SIELTGTDRYRVAVKTLNSVSGHPSDSSVIVSSKTLFEVSKTLGNLESEISVFIKNDGE FT NKVIGFESGNKTVTSLLISGNYPPVAKLFTEETGHYAILKTSDFLESTKRVSVVVERDE FT PIEFSFVKNTVTIKGSGIALASEKVECELFGDEISIMLRPQFLCDGLIACQEDFIKVAF FT TKPSVKNRPGPVLITPKLSNKEKIDFKYLLQPNLFAK" FT misc_feature 1767..2118 FT /note="DNA polymerase III beta subunit, N-terminal domain FT Score = 115.6 E-value = 6.6e-32" FT misc_feature 2145..2502 FT /note="DNA polymerase III beta subunit, central domain FT Score = 60.4 E-value = 2.7e-15" FT misc_feature 2508..2886 FT /note="DNA polymerase III beta subunit, C-terminal domain FT Score = 1.7 E-value = 0.00015" FT CDS 2890..3981 FT /transl_table=11 FT /gene="recF" FT /locus_tag="TW003" FT /product="DNA replication and repair protein recF" FT /note="Similar to Streptomyces coelicolor DNA replication FT and repair protein RecF or SCO3876 or SCH18.13c FT SWALL:RECF_STRCO (SWALL:P36176) (373 aa) fasta scores: E(): FT 3.9e-24, 37.16% id in 374 aa" FT /db_xref="GOA:Q83NZ4" FT /db_xref="InterPro:IPR003395" FT /db_xref="UniProtKB/Swiss-Prot:Q83NZ4" FT /protein_id="CAD66695.1" FT /translation="MQNNLISHINLRNFRNYEYQSISFTDGLNLIRGDNGQGKTNLAEA FT IYFLSGFGSHRTYKNQPLIKSGEQKAEISAKIQSKYGTRNVYIGISCNSNNILKVDGKP FT SKLRDLVSVFSCVIFSPEDIDLVKGDPGHRRKYLDDIICRARPMMLDIYSAYDRTLKQR FT NSLLKSFRKSSCKSDLLDIWTQKLVELGLEIVNARKRLLKILNPKISEFYSKLAGVSST FT AELFCQSSDCLIDTFDLLRDREIEEGVTLAGPHRDNVDILLNSCPARSQSSQGESWTLA FT LSMKLSLIELMRETKRLYDPDPVVILDDVFAHLDSYRKQKLAQEVFSYEQTIVTTTDNS FT DNYRTSQTLVVEEGKVFSENKKG" FT misc_feature 2899..3316 FT /note="RecF/RecN/SMC N terminal domain Score = -8.3 E-value FT = 6e-07" FT misc_feature 2986..3009 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 3802..3855 FT /note="PS00618 RecF protein signature 2." FT CDS 4011..4445 FT /transl_table=11 FT /locus_tag="TW004" FT /product="hypothetical protein" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein SCO3875 or SCH18.12c SWALL:Y2H5_STRCO FT (SWALL:P35925) (190 aa) fasta scores: E(): 5.9, 24.32% id FT in 111 aa" FT /db_xref="InterPro:IPR007922" FT /db_xref="UniProtKB/TrEMBL:Q83IG5" FT /protein_id="CAD66696.1" FT /translation="MNQYLKISNTAGYCRPIQDFSSNPFDPGRDPVWVSNLVGDFIKKF FT DCNNCLKGNNISNIWPEVVGDFGARNTEVVEITRKGELVISCLSRAIALSFRVYSEDII FT KKLNDRYPDLNLEKLIFVPPESRRGYFGPKLVRNVDKHYE" FT CDS 4485..6434 FT /transl_table=11 FT /gene="gyrB1" FT /locus_tag="TW005" FT /product="DNA gyrase subunit B" FT /EC_number="5.99.1.3" FT /note="Similar to Bacillus halodurans DNA gyrase subunit B FT GtrB or BH0006 SWALL:GYRB_BACHD (SWALL:O50627) (637 aa) FT fasta scores: E(): 1.1e-136, 56.74% id in 645 aa" FT /db_xref="GOA:Q83IG4" FT /db_xref="HSSP:1AJ6" FT /db_xref="InterPro:IPR002288" FT /db_xref="UniProtKB/TrEMBL:Q83IG4" FT /protein_id="CAD66697.1" FT /translation="MVDTPEPAYGADQIQVLEGLEAVRRRPGMYIGSTGSRGLHHLVYE FT LVDNSVDEALAGYCTKINVAILADGGVRVTDNGRGIPVDIHPKEGVSTVQVVLTTLHAG FT GKFGSGGYSVSGGLHGVGSSVVNALSKRLYVEVSRQGFVFRQNYEGGNPTAALERCEET FT NATGTAITFWPDDDIFETVCFEYEVLRSRLQQMAFLNSGLTVSITDERVDSPTNNETYC FT YQNGLFDYVMYQNRIRKHEPLHEEIIHFQAENKDRLMSLEVAMRWTSSSTENIYTFANT FT INTHEGGTHEEGFRAALTSLVNRYAREKGFLKEKDESLQGEDIREGLTAIISVKLGEPQ FT FEGQTKTKLGNTEMRGYVHHEVNSYLWDWFDSHPAQAKVIISKALLAAEARLAAKRARE FT ASRKRGLFESVSMPGKLKECQAKDPAVSELFIVEGDSAGGSAIQGRDPLTQAVLPLRGK FT ILNVEKARLDKAIANSEIQAMLTAFGSGIAEDFDESKARYHKIILMSDADVDGQHITTL FT LLTLLFRYMRPLIESGYVYLAHPPLYRIKWSNSEHDYVFSDRERDKKLAEGKLSGKKIP FT KENAIQRYKGLGEMNYRELWDTTMNPATRTLRQITVDDVTLADEIFSVLMGEDVDSRRK FT FIQHNARDVRFLDI" FT misc_feature 4584..5013 FT /note="Histidine kinase-, DNA gyrase B-, and HSP90-like FT ATPase Score = 94.1 E-value = 2e-25" FT misc_feature 5160..5682 FT /note="DNA gyrase B Score = 261.5 E-value = 7.7e-76" FT misc_feature 5775..5801 FT /note="PS00177 DNA topoisomerase II signature." FT misc_feature 5853..6096 FT /note="Toprim domain Score = 47.8 E-value = 1.7e-11" FT misc_feature 6204..6396 FT /note="DNA gyrase B subunit, carboxyl terminus Score = FT 135.1 E-value = 8.7e-38" FT CDS 6438..8897 FT /transl_table=11 FT /gene="gyrA1" FT /locus_tag="TW006" FT /product="DNA gyrase subunit A" FT /EC_number="5.99.1.3" FT /note="Similar to Streptomyces coelicolor DNA gyrase FT subunit A GyrA or SCO3873 or SCH18.10c SWALL:GYRA_STRCO FT (SWALL:P35885) (857 aa) fasta scores: E(): 1.8e-189, 61.26% FT id in 808 aa" FT /db_xref="GOA:Q83IG3" FT /db_xref="HSSP:1AB4" FT /db_xref="InterPro:IPR013757" FT /db_xref="UniProtKB/TrEMBL:Q83IG3" FT /protein_id="CAD66698.1" FT /translation="MSEQNINQVDLREEMQRSYLDYAMSVIIGRALPDVRDGLKPVHRR FT VLYAMYKGGYRPEKAFSKCARVVGDVMGQFHPHGDAAIYDALVRLVQPWAMRYPLAQGQ FT GNFGSPGNDGAAAPRYTETKMATLAIEMVRDIDEDTVDFSPNYDGESVEPTVMPCRFPN FT LLVNGSVGIAVGMATNIPPHNLAEVSAGALWCLENPDATDEELTEALLERIKGPDFPTG FT ATVLDTGGIKDAYLTGRGSVVMRGVVDIEEIDGRTCLVVRELPYQVNPDNLALKIASLV FT KENKLSGIADIRDETSGRTGQRLIIVLKRDAVARVVLNSLYKHTQLQENFGVNMLAIVD FT GAPRTLSLCSFIRLWVEHQIEVIVRRTTFRLARAEQRAHILRAYLRALDQIDEVIQLIR FT SSKSAEEAQSNLMALLKIDETQARAILDLQLRRLAALERQRIISEAREIEELISSFRKI FT LSDKTAQCQVIAEELREIGQKHSDARRTEIIRGFDGSVSIEDLIPVEPVVVVMTRCGYI FT KRTRIDQYRSQHRGGRGVKGAQVKADDVVLQFISTTTHNWLMFFTNTGRVYRAKAYEVP FT EASREARGQHVANLLPLKPNEAVTRILSVSNFDSEDTSLVLATKDGYVKKTTLKEYDTS FT LSTGVIAIKLRPGDKLVSAVLARSDQDIILVTKNARSLRFKSGTLRPLSRGSYGVKGIS FT LRENDLLLSAELILSDDSYIFVVSERGYAKRSRVGDYKLQARGGIGVRVANITEQKGVL FT ADMLVVNDDDEVLVILASGKVIRSSVAEVSPTLRYTTGVVFVRMSDGDKILAMTIAEKC FT DDLEGQG" FT misc_feature 6525..7878 FT /note="DNA gyrase/topoisomerase IV, subunit A Score = 899.7 FT E-value = 6.1e-268" FT misc_feature 7950..8097 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 52.8 E-value = 5.4e-13" FT misc_feature 8100..8256 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 50.6 E-value = 2.5e-12" FT misc_feature 8271..8412 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 48.9 E-value = 7.8e-12" FT misc_feature 8415..8562 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 43.8 E-value = 2.7e-10" FT misc_feature 8568..8718 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 46.4 E-value = 4.4e-11" FT misc_feature 8721..8868 FT /note="DNA gyrase C-terminal domain, beta-propeller Score = FT 31.1 E-value = 1.8e-06" FT CDS 8894..9274 FT /transl_table=11 FT /locus_tag="TW007" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces coelicolor putative integral FT membrane protein SCO3872 or SCH18.09c SWALL:Q9KXX6 FT (EMBL:AL357152) (185 aa) fasta scores: E(): 0.0026, 30.5% FT id in 118 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NZ3" FT /protein_id="CAD66699.1" FT /translation="MNTKLVKSSSSQAVLRLGSINVVSAARTAFVFSLAFSVVMFLLIL FT MLYMFLNFAGVFNISAVGGTPEGAPADFTLSNAISPWTVLIFSLILAGTNVFTFTTGAI FT IFSVIYNVIARITGGLRFTFYR" FT misc_feature 8894..9085 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.950) with cleavage FT site probability 0.633 between residues 64 and 65" FT misc_feature order(8978..9046,9137..9232) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 29-51 and 82-113" FT tRNA 9278..9351 FT /note="tRNA Ile anticodon GAT, Cove score 79.47" FT tRNA 9365..9441 FT /note="tRNA Ala anticodon TGC, Cove score 94.27" FT CDS complement(9640..10332) FT /transl_table=11 FT /locus_tag="TW008" FT /product="conserved hypothetical protein" FT /note="Similar to Thermoanaerobacter tengcongensis thiamine FT pyrophosphokinase Thi80 or Tte1497 SWALL:Q8R9T9 FT (EMBL:AE013107) (211 aa) fasta scores: E(): 2.5e-09, 29.68% FT id in 192 aa, and to Bacillus subtilis YloS protein FT SWALL:O34664 (EMBL:Z99112) (214 aa) fasta scores: E(): FT 5.7e-08, 30% id in 210 aa" FT /db_xref="GOA:Q83IG2" FT /db_xref="InterPro:IPR007371" FT /db_xref="UniProtKB/TrEMBL:Q83IG2" FT /protein_id="CAD66700.1" FT /translation="MLGMGVCYIYGAGEHFTPPEEVGMHDLVIAADGGLMQLKKHGARI FT DLYVGDLDSIESIPINIDRVILPREKDKTDMMQAALIGAERGFRTFCIFGGTGGRLDHT FT IGNIQLLAELTNMGYSVFIVGKYDVVTAIRNNEIYFPSHFTGNISIFPHSGDASGVYEE FT GLKYALNNAHIPGTFNGVSNEFIGVKSRVAVESGMLLVVYERQGGRMHLNISTCAMTAG FT NQIQKPSG" FT misc_feature complement(9957..10299) FT /note="Thiamin pyrophosphokinase, catalytic domain Score = FT 80.0 E-value = 3.5e-21" FT CDS 10472..11095 FT /transl_table=11 FT /locus_tag="TW009" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces coelicolor putative membrane FT protein SCO3855 or SCH69.25c SWALL:Q9XA09 (EMBL:AL079308) FT (297 aa) fasta scores: E(): 9.4e-13, 40% id in 155 aa" FT /db_xref="GOA:Q83NZ2" FT /db_xref="InterPro:IPR002610" FT /db_xref="UniProtKB/TrEMBL:Q83NZ2" FT /protein_id="CAD66701.1" FT /translation="MIIWRRLRAYPPATATIITLCIFLWLLQMLLGSGVTTSLAFAGAY FT VFPDSLQPWRIFTSMFLHSTFTPLHLLFNMYSLWWLGSNLEQRIGSWRFLALYFISGLG FT AAVGIVYLQPYNTLTLGASGGIFGLLAAFIVLRIDSGQLWGIVGLNLIISFLLPGVSWQ FT AHIGGLLSGFVAAWAIKRRNPLLLGAQVILLIGVIATRPYLLYA" FT misc_feature 10472..10591 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.992) with cleavage FT site probability 0.460 between residues 40 and 41" FT misc_feature order(10538..10606,10649..10717,10736..10804,10814..10882, FT 10901..10969,11027..11086) FT /note="6 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 23-45, 60-82, 89-111, FT 115-137, 144-166 and 186-205" FT misc_feature 10610..11021 FT /note="Rhomboid family Score = 144.6 E-value = 1.3e-40" FT CDS complement(11133..11342) FT /transl_table=11 FT /locus_tag="TW010" FT /product="putative membrane protein" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein SCO3854 or SCH69.24 SWALL:Q9XA10 (EMBL:AL079308) FT (84 aa) fasta scores: E(): 1.4e-08, 40% id in 55 aa, and to FT Corynebacterium glutamicum hypothetical membrane protein FT Cgl0040 cgl0040 SWALL:BAB97433 (EMBL:AP005274) (90 aa) FT fasta scores: E(): 6.5e-06, 33.33% id in 63 aa" FT /db_xref="GOA:P67379" FT /db_xref="InterPro:IPR009619" FT /db_xref="UniProtKB/Swiss-Prot:P67379" FT /protein_id="CAD66702.1" FT /translation="MSRKKHESSENNPVWFPTIMFGLMGTGAVWMVLFYISNGALPLPA FT VGTWNILIAFGIIMAGFAMMSRWK" FT misc_feature complement(order(11151..11210,11238..11306)) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35 and 45-64" FT CDS 11399..12037 FT /transl_table=11 FT /locus_tag="TW011" FT /product="putative glutamine amidotransferase" FT /note="Similar to Streptomyces coelicolor putative FT glutamine amidotransferase SCO3851 or SCH69.21c FT SWALL:Q9XA13 (EMBL:AL079308) (212 aa) fasta scores: E(): FT 1.8e-29, 43.68% id in 206 aa, and to Escherichia coli FT para-aminobenzoate synthase glutamine amidotransferase FT component II PabA or b3360 SWALL:PABA_ECOLI (SWALL:P00903) FT (187 aa) fasta scores: E(): 5e-24, 41.48% id in 188 aa" FT /db_xref="GOA:Q820C3" FT /db_xref="HSSP:1QDL" FT /db_xref="InterPro:IPR001317" FT /db_xref="UniProtKB/TrEMBL:Q820C3" FT /protein_id="CAD66703.1" FT /translation="MFKVLVIDNHDSFIYTLVNYLQQLGVTTSVVRSDNNCHSVESMLG FT VHDAALISPGPGTPEESGITLSVIRAAYSTSTPLLGVCLGHQALAVAFGGDIGPSGRIM FT HGKLVTVRPRPSAIFKDLPTAFTATRYNSLTVTKVPQALRVIARADCGEVMALEHRTAP FT MYGVQFHPESAVSEWGFRILGNWLYISGFNKALGISRDLPIVVYNTRVR" FT misc_feature 11411..11966 FT /note="Glutamine amidotransferase class-I Score = 180.3 FT E-value = 2.2e-51" FT misc_feature 11630..11665 FT /note="PS00442 Glutamine amidotransferases class-I active FT site." FT CDS 12143..12715 FT /transl_table=11 FT /locus_tag="TW012" FT /product="conserved hypothetical membrane protein" FT /note="Similar to Rhizobium meliloti hypothetical FT transmembrane protein SMC00853 or R00853 SWALL:Q92RL3 FT (EMBL:AL591785) (182 aa) fasta scores: E(): 6.7e-26, 49.18% FT id in 183 aa" FT /db_xref="InterPro:IPR007156" FT /db_xref="UniProtKB/TrEMBL:Q83IG1" FT /protein_id="CAD66704.1" FT /translation="MDGVFLWVTLGLALAIVVIAIFAWVAYNRLVAYNVRVDEAWSDIT FT VQLKRRADLIPSLIETVKGYASHEKSVFKQVTLARAASIGASGVAEAAAADNQLQAALK FT SIFAVAEAYPQLQASQNFLDLQAQLTDTENKIQASRRFYNGGVRDLNTLIGVFPSNIVA FT RIAKFSTREFFDVERSEALQSPPKIVF" FT misc_feature 12143..12217 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.916) with cleavage FT site probability 0.503 between residues 25 and 26" FT misc_feature 12152..12220 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 4-26" FT misc_feature 12164..12710 FT /note="LemA family Score = 254.7 E-value = 9e-74" FT CDS 12752..13627 FT /transl_table=11 FT /locus_tag="TW013" FT /product="putative integral membrane heat shock protease" FT /note="Similar to Streptococcus gordonii Challis probable FT protease HtpX homolog SWALL:HTPX_STRGC (SWALL:O30795) (297 FT aa) fasta scores: E(): 1.5e-41, 42.52% id in 301 aa, and to FT Escherichia coli probable protease HtpX or b1829 FT SWALL:HTPX_ECOLI (SWALL:P23894) (293 aa) fasta scores: E(): FT 4.9e-17, 32.05% id in 287 aa" FT /db_xref="GOA:Q83IG0" FT /db_xref="InterPro:IPR001915" FT /db_xref="UniProtKB/Swiss-Prot:Q83IG0" FT /protein_id="CAD66705.1" FT /translation="MMYSFIARNKINTFLILFVFILACGGFGLLAGRFLGMSFFLFILL FT LAAGYACVQYFFSGRLAVLMSGARKISRNDNPRLWNTVENLSITTGLPMPEVYIVDDPA FT PNAFATGRDPKHAKVAATSGLLEILDDSELEGVMAHEMGHVKNYDIRVSTIVFGLVSAV FT GLISDMVLRALIWGDNRREGNSAFSFAIVLFFSLLAPIAAMLVQLAVSREREYLADATG FT ALTTRYPAALASALAKLEGNARPLQRQSSSMAHLWISNPMPRGFFRKLFSTHPPTEERI FT RRLKEMGNQF" FT misc_feature 12752..12895 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.984) with cleavage FT site probability 0.241 between residues 48 and 49" FT misc_feature order(12788..12856,12866..12934,13211..13279,13307..13375) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35, 39-61, 154-176 and FT 186-208" FT misc_feature 12995..13601 FT /note="Peptidase family M48 Score = 115.6 E-value = FT 6.5e-32" FT CDS 13628..13999 FT /transl_table=11 FT /locus_tag="TW014" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces coelicolor putative integral FT membrane protein SCO1562 or SCL11.18 SWALL:Q9L1C0 FT (EMBL:AL157953) (138 aa) fasta scores: E(): 1.2e-12, 41.02% FT id in 117 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NZ1" FT /protein_id="CAD66706.1" FT /translation="MAKVLFASYALLAVASLGRSAYQISTRFYEAPLAYSLSGFAAIVY FT LVVFVSLVYSLRCLAYCALFIELIGVVVIGTLSIFAPGLFGTGNHIAATVWTLYGVGYF FT FLPAALPVLGIIWLSRSKR" FT misc_feature 13628..13696 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.767) with cleavage FT site probability 0.217 between residues 23 and 24" FT misc_feature order(13640..13699,13727..13795,13814..13882,13910..13978) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-24, 34-56, 63-85 and FT 95-117" FT CDS 14121..15404 FT /transl_table=11 FT /locus_tag="TW015" FT /product="WiSP family protein" FT /note="No significant database matches" FT /db_xref="InterPro:IPR008009" FT /db_xref="UniProtKB/TrEMBL:Q83NZ0" FT /protein_id="CAD66707.1" FT /translation="MRVGCLGKEVGLVRAQAIFRLVVLSILCVSVLLPTRWVLATPALK FT PQSFSVAIGESLNRPPIPAAARGSVYTVNTKDLTAPGDGLPRGLDINRGTGTISGSVGS FT DVLPGVYKPRVSVTSSAGSTSAVYTITVTRQIVLGDVLAQIKQGDPVRIPAKIIGGHSL FT FNFRLAGKPRTTPGIAYPMGLSVDSKTGVLFGTVSYEVEYGVYNFLLWADEVIHGEIVS FT HFAYYTLLVSPMHFNVDDQNFELQAYKPFQFPLSANGAAIAWVATGLPKGIYLSPAGLL FT YGVPAVPPGEYSARLTVYGLEVRSGVLKIVSVTANLNILVAGEPIIYPQSITVKKGESV FT SFPAKPPHKPGWVYWANMVDITTPGNGIPDGLILSPDNGTLYGAVSPSVQPGVYTPTVF FT KAVPGEVEYAHSTTYTITVVEGTAPGAN" FT misc_feature 14181..14240 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 21-40" FT CDS 15432..16280 FT /transl_table=11 FT /gene="dkgA" FT /locus_tag="TW016" FT /product="2,5-diketo-D-gluconic acid reductase A" FT /EC_number="1.1.1.-" FT /note="Similar to Yersinia pestis 2,5-diketo-D-gluconic FT acid reductase A DkgA or YPO0676 or y3501 SWALL:DKGA_YERPE FT (SWALL:Q8ZI40) (277 aa) fasta scores: E(): 5.3e-50, 46.71% FT id in 274 aa, and to Corynebacterium sp. FT 2,5-diketo-D-gluconic acid reductase A DkgA FT SWALL:DKGA_CORSP (SWALL:P06632) (277 aa) fasta scores: E(): FT 1.1e-55, 51.5% id in 266 aa" FT /db_xref="GOA:Q83IF9" FT /db_xref="HSSP:1HW6" FT /db_xref="InterPro:IPR020471" FT /db_xref="UniProtKB/TrEMBL:Q83IF9" FT /protein_id="CAD66708.1" FT /translation="MVFVLTYVPSVLLGDGVSIPQFGLGTYELPPNETSSVVQSAIELG FT YRHIDTASLYANEREVGRAIASSGIKREEFFVTTKLWNSDQPKPREAFERSLDLLSLDY FT VDLYLIHWPCPPSELYINVWEVLLELKESGRAKSVGVSNFLSEHINKIKEAGFPLPSVN FT QIELHPWLQQRELVLSCRNYGIQIESWGPFARFSKDLDAFPELTRPAKEYGKTPAQVIL FT RWHIQKGYVVFPKTVHAERLRQNIDIFDFDLTPDEISGIDSLDAGFRTGPDPSSFRAGL FT D" FT misc_feature 15468..16233 FT /note="Aldo/keto reductase family Score = 357.0 E-value = FT 1.4e-104" FT misc_feature 15564..15617 FT /note="PS00798 Aldo/keto reductase family signature 1." FT misc_feature 15810..15863 FT /note="PS00062 Aldo/keto reductase family signature 2." FT CDS complement(16396..18048) FT /transl_table=11 FT /locus_tag="TW017" FT /product="putative phosphomannomutase" FT /note="Similar to Streptomyces coelicolor putative FT phosphomannomutase SCO4916 or SCK13.08c SWALL:Q9AD82 FT (EMBL:AL512667) (549 aa) fasta scores: E(): 9.1e-77, 44.21% FT id in 536 aa, and to Streptococcus thermophilus FT phosphoglucomutase PgmA SWALL:Q9K560 (EMBL:AJ243290) (572 FT aa) fasta scores: E(): 1.1e-28, 33.27% id in 544 aa" FT /db_xref="GOA:Q83NY9" FT /db_xref="InterPro:IPR016066" FT /db_xref="UniProtKB/TrEMBL:Q83NY9" FT /protein_id="CAD66709.1" FT /translation="MNILRKASLWIENDPVAITRLEMRRLLAESEKTGDVRELEERLSK FT TLEFGTAGLRAPQGAGFNRVNAVVTAQAANALSQFLLEENRGRTLVIGYDGRYNSQLWA FT RNTARIASSYDITALIMPRALPTPLLAFAVRQLGAAAGVMVTASHNPREYNGYKVYLGG FT EDKGAQIPDTAAAKIAKNLRDEVAYSDIPMKDSYGILDEEIIEAYLSRTAKAIKRQFGS FT PKADLKICHTAMHGVGHEIFVRLMEKLGFHNLVFVEEQKMPDPAFPTLPFPNPEEKGAL FT DLAFETARLAECDIIIANDPDADRVAVAHPDGKVFTGNEIGALLGVEIARMQRGHGVLS FT NSMVSSPIMRRIAETYGMQHVETPTGFKWVARVPDICFGFEEALGYMIHPELVRDKDGL FT SAGAAIATIAASQKAQGRSLRDCLDDLQSKLGYFRSTQYAVRMASLDSVQAVMQNLRAE FT SLNKIGRFRVTKYRDLLFGSPPVDLLEFNLGQDIDDLFGRLIVRPSGTELKLKCYIDSV FT AKTPDGAEQLLSELTYACKNLLCETSRRGGAEN" FT misc_feature complement(16773..17100) FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain III Score = 14.2 E-value = 0.00014" FT misc_feature complement(17106..17433) FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain II Score = 11.1 E-value = 3.8e-05" FT misc_feature complement(17472..17922) FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain I Score = 147.4 E-value = 1.8e-41" FT misc_feature complement(17581..17625) FT /note="PS00710 Phosphoglucomutase and phosphomannomutase FT phosphoserine signature." FT CDS complement(18061..18894) FT /transl_table=11 FT /gene="punA" FT /locus_tag="TW018" FT /product="purine nucleoside phosphorylase" FT /EC_number="2.4.2.1" FT /note="Similar to Cellulomonas sp purine nucleoside FT phosphorylase PunA SWALL:PUNA_CELSP (SWALL:P81989) (282 aa) FT fasta scores: E(): 6.6e-45, 48.33% id in 271 aa" FT /db_xref="GOA:Q83IF8" FT /db_xref="HSSP:1QE5" FT /db_xref="InterPro:IPR001369" FT /db_xref="UniProtKB/TrEMBL:Q83IF8" FT /protein_id="CAD66710.1" FT /translation="MEDICNTELTAATLAAKQIADITGIARHDIAVTLGSGWVDAVSNL FT GELITTIPAQDIHGFFPPVLAGHSGVLTSIRLTCGVYVLVIGARTHLYQGHGPEAVVHG FT IKTAHAAGARVAILTNGAGSTVPDWGPGEVVVIKDHINLTGKSPLSGANFCDMSDIYTA FT ALRQKILQMAPNIPQGVYAQMPGPQYETPAEVKMLRTIGADLVGMSTALEAIMAKSLKM FT NVVGLSLVTNLAAGIGTGQLSHDEVLTVSEQARQKTSAFLVELIRDIGQDLSGRK" FT misc_feature complement(18084..18816) FT /note="Phosphorylase family 2 Score = 185.7 E-value = FT 5.4e-53" FT CDS 18975..20372 FT /transl_table=11 FT /locus_tag="TW019" FT /product="putative oxidoreductase" FT /note="Similar to Corynebacterium glutamicum FT dihydrolipoamide dehydrogenase/glutathione oxidoreductase FT and related enzymes cgl0688 SWALL:BAB98081 (EMBL:AP005276) FT (469 aa) fasta scores: E(): 6.5e-76, 48.58% id in 459 aa, FT and to Bacillus subtilis dihydrolipoamide dehydrogenase FT PdhD or AceD or CitL SWALL:DLD1_BACSU (SWALL:P21880) (470 FT aa) fasta scores: E(): 1.6e-35, 30.99% id in 442 aa" FT /db_xref="GOA:Q83NY8" FT /db_xref="HSSP:3LAD" FT /db_xref="InterPro:IPR006258" FT /db_xref="UniProtKB/TrEMBL:Q83NY8" FT /protein_id="CAD66711.1" FT /translation="MSVKKNHKIVVIGGGPGGYSAALSGALLGADVVLIENQAVGGSAT FT LTDVVPSKTLIASAERAVFVAQGADFGIRFQNCVSADIGHINRRIMDLTRAQSADMFST FT LTGAGVRVVYGHAALDGPNRVLVSVSGQEKYEFFANTVVVATGSSPRVLPNAIPDGKRI FT LTWKQLYTLEQVPEHIIVVGSGVTGAEFASAFRNLGSEVTLVSSRDRVLPGGDEDAADL FT IQEVFINSGMKLLNRARAQAAAACNGGVVVTLTDGTEVRGTHCLMAVGSVPNTSGIGLE FT TANIALNPAGRITVNRVACSSVPGVYAAGDCSDFLPLASVAEMQGQVAVYHAMGENANP FT IELKNLASTVFTTPEIATVGRSEKAIDKARATALKVDLATNSRAKILGIKTGFVKMIVS FT RETGTVLGGVVVAPNASDLIFPISVAVQNRLSADQLSQSFAVYPSLTISLWHAARASHV FT RTDSASP" FT misc_feature 18975..19061 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.772) with cleavage FT site probability 0.272 between residues 29 and 30" FT misc_feature 18996..19935 FT /note="Pyridine nucleotide-disulphide oxidoreductase Score FT = 221.0 E-value = 1.2e-63" FT misc_feature 20010..20331 FT /note="Pyridine nucleotide-disulphide oxidoreductase, FT dimerisation domain Score = 91.6 E-value = 1.1e-24" FT CDS complement(20441..22216) FT /transl_table=11 FT /locus_tag="TW020" FT /product="putative acyl-CoA carboxylase complex A subunit" FT /note="Similar to Streptomyces coelicolor putative acyl-CoA FT carboxylase complex A subunit AccA1 SWALL:Q9RGQ6 FT (EMBL:AF113603) (590 aa) fasta scores: E(): 2.3e-110, FT 51.67% id in 596 aa, and to Mus musculus pyruvate FT carboxylase, mitochondrial precursor SWALL:PYC_MOUSE FT (SWALL:Q05920) (1178 aa) fasta scores: E(): 1.6e-71, 42.26% FT id in 504 aa" FT /db_xref="GOA:Q83NY7" FT /db_xref="HSSP:1DV1" FT /db_xref="InterPro:IPR005482" FT /db_xref="UniProtKB/TrEMBL:Q83NY7" FT /protein_id="CAD66712.1" FT /translation="MKKITRLLIANRGEIAVRVIRACRDKAIASIAIYSDQDRDAVHTQ FT LADEAYCLEGETAAETYLNIEKILDIAKLSRADGIHPGYGFLAESPEFAEAVSSAGITW FT VGPRAGVIALLADKLSARKIAEQVGVPVPPGGEHVVSCASEVHNFADKYGLPIAIKAAY FT GGGGLGMKVVKQKKNIDELFASAQREAQAAFGNKECFIEKYIDRPRHVETQCLADLFGN FT VQVVSTRDCSVQRRHQKLIEEAPAYTLTDKQEETLITASKAVMKAAEYSGAGTCEFLID FT QDGKIFFLEVNARLQVEHPVTEEITGIDLVLEQINIAEGKLLKNLETPVYKGHSLEFRI FT NAEDANSGFMPRHGKVVKFEPPGGLGIRIDSGIKAGDTIGAAFDSLLCKLIVTGNNREC FT ALARARRALDEFVIDGVTTLIPFHRNILNQPDFINGGMYTGWVENEYSKLVNKQTDAST FT VPDIQDTLSVSKNLREIIVEVNRKQIRVRLPSPIGEYPTERQKPPGRRVGHNFRQKTQE FT KNPDSIFSPMQAVVVKVNVTEGQSVKKDDLLIVLEAMKMEQPIVAPRDGVVEKINAHTG FT ETVPSGHELLRLKKV" FT misc_feature complement(20455..20656) FT /note="Biotin-requiring enzyme Score = 73.7 E-value = FT 2.7e-19" FT misc_feature complement(20890..21208) FT /note="Biotin carboxylase C-terminal domain Score = 180.6 FT E-value = 1.8e-51" FT misc_feature complement(21229..21868) FT /note="Carbamoyl-phosphate synthase L chain, ATP binding FT domain Score = 301.7 E-value = 6.5e-88" FT misc_feature complement(21332..21355) FT /note="PS00867 Carbamoyl-phosphate synthase subdomain FT signature 2." FT misc_feature complement(21874..22210) FT /note="Carbamoyl-phosphate synthase L chain, N-terminal FT domain Score = 149.0 E-value = 6e-42" FT CDS complement(22333..22752) FT /transl_table=11 FT /locus_tag="TW021" FT /product="hypothetical protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83IF7" FT /protein_id="CAD66713.1" FT /translation="MVNMTKTEARAANAAFWQYPAHQPQQRPEFTTDSISRAHTTYMYA FT QYRYATHWACTLLRVIHLSREEETAAALAAIMFIESESCRDVNSKAINKTTDCCNERNT FT KNNWNIRVWSTRSWPSGGTLLPRKYEPLICRQWAR" FT CDS 22844..23152 FT /transl_table=11 FT /locus_tag="TW022" FT /product="hypothetical protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83IF6" FT /protein_id="CAD66714.1" FT /translation="MDFDPGKCVIGAINKVFSVDSISTTVGFTLLDKMVKVLKVSIKLT FT RLINFSSIVLTAIDAVTGCLEGGIVSTETPVHPVPIVSSDCSAYDMGHKLGYRCQRR" FT CDS 23168..23563 FT /transl_table=11 FT /locus_tag="TW023" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NY6" FT /protein_id="CAD66715.1" FT /translation="MWRKLASVPALIIYLAFVPVLTVAAEIYVLTGYSLPWLGIPAFAL FT VIITINSGLLPNRDVSPSRLARLAVYLALAALIVFVVVCMTIYFTVGLSRLARFDVLAP FT FVLGYLLASALSVELCYKLKAKKSGKV" FT misc_feature 23168..23242 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.996) with cleavage FT site probability 0.972 between residues 25 and 26" FT misc_feature order(23186..23254,23264..23332,23369..23437,23468..23536) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29, 33-55, 68-90 and FT 101-123" FT CDS 23661..23798 FT /transl_table=11 FT /locus_tag="TW024" FT /product="putative integral membrane protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NY5" FT /protein_id="CAD66716.1" FT /translation="MAYELHNLLHCAVPYDLLVFSRYIAFTVVAVSPIFWLIPGNYALL FT " FT misc_feature 23724..23792 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 22-44" FT CDS complement(24099..25676) FT /transl_table=11 FT /gene="pccB" FT /locus_tag="TW025" FT /product="propionyl-CoA carboxylase beta chain" FT /EC_number="6.4.1.3" FT /note="Similar to Saccharopolyspora erythraea propionyl-CoA FT carboxylase beta chain PccB SWALL:PCCB_SACER (SWALL:P53003) FT (546 aa) fasta scores: E(): 8.9e-123, 62.5% id in 520 aa" FT /db_xref="GOA:Q83IF5" FT /db_xref="HSSP:1ON3" FT /db_xref="InterPro:IPR000438" FT /db_xref="UniProtKB/TrEMBL:Q83IF5" FT /protein_id="CAD66717.1" FT /translation="MTDNFDESSRGLEKYRQAYEVAVTLREDSAKEKQHSKGKMTARER FT IDKLLDENSFTEIDQFAMHSASGFGIEKNHPYGDSVVTGFGSIDGRKVAVYSQDFTVFG FT GSLGEVAGRKIVKTMDLAMSAGIPVIGLLDSGGARIQEGIAALTKYGEIFKRNVAASGI FT IPQISIVMGPAAGGACYSPALTDFVIMVDQISYMFITGPDVIKAVTGEEVTFEDLGGAN FT MHNATSGVSHYMAHSEDDAIAYARELIGFLPSNNMSDPPTWPQDIHTEESDLELNSIVP FT ENPNKPYDMQFVIERIVDDGNFLEIQSAYAKNVIIGFARISGFSIGIVANQPAHMAGAL FT DINASEKAARFVRFCDAFSIPILTLVDVPGYLPGTEQEWTGIIRRGAKLLYAYSEATVP FT MVTIILRKAYGGAYIVMGSKALGADINLAWPSAEIAVMGAQGAVNILYRNDIKRLVQAG FT EDANPMKEKLVKEYTDKFANPFIAAQRGYLDAIIEPAQTRIAIATAFQTIRTKRYKQID FT RKHGSIPL" FT misc_feature complement(24110..25625) FT /note="Carboxyl transferase domain Score = 893.4 E-value = FT 4.8e-266" FT CDS 25738..26484 FT /transl_table=11 FT /locus_tag="TW026" FT /product="putative protein ligase" FT /note="Similar to Mycobacterium tuberculosis BirA or FT Rv3279c or mtcy71.19c or mt3379 SWALL:P96884 (EMBL:Z92771) FT (266 aa) fasta scores: E(): 2.8e-16, 36.11% id in 252 aa, FT and to Bacillus subtilis BirA bifunctional protein FT [includes: biotin operon repressor; FT biotin--[acetyl-coa-carboxylase] synthetase BirA FT SWALL:BIRA_BACSU (SWALL:P42975) (325 aa) fasta scores: E(): FT 1.6e-11, 30.4% id in 250 aa" FT /db_xref="GOA:Q83IF4" FT /db_xref="HSSP:1BIA" FT /db_xref="InterPro:IPR004408" FT /db_xref="UniProtKB/TrEMBL:Q83IF4" FT /protein_id="CAD66718.1" FT /translation="MFPCVFLDTVGSTNLYLLELLKAKDLDDFFAVFTTNQTAGRGRMA FT RSWECKKGIALSVFLKHNLPGAYINWLPLVIGLAVVKAVNKMLEDATLPHRADIKWPND FT VLINGKKLSGILIETPSDGNGLIVGIGLNVAVAPIATSICLRQVGLQASPKEVVSALLA FT EMHTIYQQLIALAAKDISFKDSECFGEIMRLCSTINKTVRVTGTKTFVGVAQGLDSLGR FT LVIRHSGDTSIVSAGDIEHLRAIDSL" FT misc_feature 25744..26155 FT /note="Biotin/lipoate A/B protein ligase family Score = FT 84.2 E-value = 1.9e-22" FT misc_feature 26326..26461 FT /note="Biotin protein ligase C terminal domain Score = 41.4 FT E-value = 1.4e-09" FT CDS complement(26537..26869) FT /transl_table=11 FT /locus_tag="TW027" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces coelicolor putative integral FT membrane protein SCO4845 or SC5G8.13 SWALL:Q9KZA1 FT (EMBL:AL353872) (157 aa) fasta scores: E(): 2.9e-08, 41.3% FT id in 92 aa" FT /db_xref="GOA:Q83NY4" FT /db_xref="InterPro:IPR007267" FT /db_xref="UniProtKB/TrEMBL:Q83NY4" FT /protein_id="CAD66719.1" FT /translation="MLLGFRNIAYGSVLAASVAVIVSISFNWIGNRHLVFRGLRRDGVL FT REAVRFFLVSIGGSLVQLACLVVSHYGMGFTSILADNIASNLVGLPLATVLRFIGYYFW FT VFSKRK" FT misc_feature complement(26554..26869) FT /note="GtrA-like protein Score = 36.2 E-value = 5.2e-08" FT misc_feature complement(order(26555..26623,26651..26719,26780..26842)) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 10-30, 51-73 and 83-105" FT CDS 26979..28232 FT /transl_table=11 FT /gene="purK" FT /locus_tag="TW028" FT /product="phosphoribosylaminoimidazole carboxylase ATPase FT subunit PurK" FT /EC_number="4.1.1.21" FT /note="Similar to Mycobacterium tuberculosis FT phosphoribosylaminoimidazole carboxylase ATPase subunit FT PurK or Rv3276c or mt3376 or mtcy71.16C SWALL:PURK_MYCTU FT (SWALL:P96881) (429 aa) fasta scores: E(): 1.3e-21, 39.43% FT id in 421 aa, and to Schizosaccharomyces pombe FT phosphoribosylaminoimidazole carboxylase Ade6 or Min1 or FT Spcc1322.13 SWALL:PUR6_SCHPO (SWALL:P15567) (552 aa) fasta FT scores: E(): 1.5e-14, 32.15% id in 395 aa" FT /db_xref="GOA:Q83IF3" FT /db_xref="HSSP:1B6R" FT /db_xref="InterPro:IPR005875" FT /db_xref="UniProtKB/TrEMBL:Q83IF3" FT /protein_id="CAD66720.1" FT /translation="MLSIARIASPAQYNLRLMFERLSCSVGVIGGGQLARMMIAPAQAL FT GVDLKVFADTPDSSAALAATAFGSPENGAAVLEFAQTVDIVTFEHELVPADVLQLLDER FT GIEMLPCPRALRYAQDKLALRRYLDEISVNQPAWAEVRSEGDLERFISEHGGCAVVKTG FT GYDGRGVQVVTLSSEIDTCRNGGFLAEERIDFVCEVSQLVARSSIGEICVWPLTQTIQE FT NGICVQTITPALGLSGGNALNQLTTFHDGRTRTPHAPLHSELITKLQDSAKTIALDIAR FT GLNVVGVMAVEMFITQDGKLLVNELAMRPHNSGHWSMAASITDQFEQHLRAVLGLPLGA FT TDMSHNCAIMVNIFNSISPAQYREVMTHWPDAKLHIYKKQPRPGRKIGHVVFAGEDLQQ FT LAIAAEECRQLLRESHAV" FT misc_feature 27135..27588 FT /note="ATP-grasp domain Score = 56.7 E-value = 3.6e-14" FT CDS 28311..28853 FT /transl_table=11 FT /gene="purE" FT /locus_tag="TW029" FT /product="phosphoribosylaminoimidazole carboxylase FT catalytic subunit PurE" FT /EC_number="4.1.1.21" FT /note="Similar to Corynebacterium ammoniagenes FT phosphoribosylaminoimidazole carboxylase catalytic subunit FT PurE SWALL:PUR6_CORAM (SWALL:Q44679) (177 aa) fasta scores: FT E(): 7.7e-28, 55.09% id in 167 aa, and to Streptomyces FT coelicolor phosphoribosylaminoimidazole carboxylase FT catalytic subunit PurE or SCO3059 or SCBAC19G2.14c FT SWALL:Q93J44 (EMBL:AL596138) (180 aa) fasta scores: E(): FT 3.7e-27, 54.21% id in 166 aa" FT /db_xref="GOA:Q83IF2" FT /db_xref="HSSP:1O4V" FT /db_xref="InterPro:IPR000031" FT /db_xref="UniProtKB/TrEMBL:Q83IF2" FT /protein_id="CAD66721.1" FT /translation="MTGKNINDEGSKCPALVWLLMGSDSDWPVMSGAADILQQMNISFR FT VNVVSAHRQPEKMISCAKRARDMGFKVLIAAAGGAAHLPGMLASVTTLPVIGVPVGQKN FT LSGLDSLLSIVQMPSGVPVACVGIDSAKNAALLAARILGVQSADIEASRIADSLSAYQQ FT SLFDQSNEKDRMINEPK" FT misc_feature 28353..28824 FT /note="AIR carboxylase Score = 236.9 E-value = 2e-68" FT CDS complement(29078..29476) FT /transl_table=11 FT /locus_tag="TW030" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NY3" FT /protein_id="CAD66722.1" FT /translation="MSRNVTCKPGMWEAVTLALVAYSSAIASILYFYSSPYATLAGGFA FT LLSVGVLSFMSFRRPRILHSRRVWSVSAVFVFFLSALFLAFFVLSPGFGVSFSLSFLYG FT VLLLATSLMSNLLLIGLICVRFPKHLEA" FT misc_feature complement(order(29111..29179,29207..29275,29312..29365, FT 29375..29443)) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 12-34, 38-55, 68-90 and FT 100-122" FT CDS complement(29804..30667) FT /transl_table=11 FT /locus_tag="TW032" FT /product="putative polysaccharide biosynthesis protein" FT /note="Similar to Streptomyces rishiriensis FT dTDP-4-keto-6-deoxyhexose reductase CouS SWALL:Q9F8T1 FT (EMBL:AF235050) (288 aa) fasta scores: E(): 4.4e-46, 48.52% FT id in 272 aa, and to Saccharopolyspora spinosa FT dTDP-4-dehydrorhamnose reductase Kre SWALL:Q93EJ9 FT (EMBL:AF355468) (305 aa) fasta scores: E(): 4.2e-36, 43.34% FT id in 293 aa" FT /db_xref="GOA:Q83NY2" FT /db_xref="HSSP:1N2S" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q83NY2" FT /protein_id="CAD66723.1" FT /translation="MSLKCLITGGGGMLGRDIRSVFPESVALTHDELDITDEYAVLDAA FT RNKDLLINCAAYTQVDAAESNAAKAYAVNEAGARAVAKAAARRSIRVVHISTDYVFSGT FT AIRPYPEDHPHSPLSVYGKSKAAGEKAVLEEYSKGSFIIRTAWLYGQYGNNFVKSILKA FT CRTQDIVTVVNDQYGQPTWSLDLAKQIKLLAESDAPCGVYHGTNSGKTTWFDFAGKVAA FT LGGYDPKRIIPISSAQFVRPARRPGYSCLGHDAWTAVGLEPMRPWEDALNDAWAAGVFA FT ECIAGQ" FT misc_feature complement(29857..30262) FT /note="RmlD substrate binding domain Score = 183.5 E-value FT = 2.3e-52" FT CDS complement(30664..31647) FT /transl_table=11 FT /locus_tag="TW033" FT /product="putative dehydratase" FT /note="Similar to Streptomyces tenebrarius AprE FT SWALL:Q9F5R6 (EMBL:AF306787) (332 aa) fasta scores: E(): FT 8.2e-88, 64.83% id in 327 aa" FT /db_xref="GOA:Q83NY1" FT /db_xref="HSSP:1BXK" FT /db_xref="InterPro:IPR016040" FT /db_xref="UniProtKB/TrEMBL:Q83NY1" FT /protein_id="CAD66724.1" FT /translation="MTHILVTGGAGFIGSNFVRRAIENKYPEIRDCTVTVLDALTYSGN FT INNLSPVRSSSRLRFIHGDIRDEDLLSEIMPNVNYVVHFAAETHVDRSIKNASAFVETN FT VLGTGRLLEAAARNNIDRFIHISTDEVYGSIESGSWDENQPLLPNSPYSASKAASDLLV FT RSYHKTYDLPVCITRCSNNYGPYQFPEKVIPLFVTNLIEDKEVPLYGDGTNVRDWLHVD FT DHCRGIYIVLTKGRSGEIYNIGGGLELSNADLSQIILEVMEKSWSMVKRVKDRPGHDKR FT YSVSINKISTLGYRPEVSFEQGLAETINWYKDNSSWWKPLKARAAL" FT misc_feature complement(30705..31638) FT /note="NAD dependent epimerase/dehydratase family Score = FT 526.7 E-value = 1.1e-155" FT misc_feature complement(31147..31233) FT /note="PS00061 Short-chain dehydrogenases/reductases family FT signature." FT CDS 31892..32515 FT /transl_table=11 FT /locus_tag="TW035" FT /product="putative epimerase" FT /note="Similar to Streptomyces antibioticus FT dTDP-4-keto-6-deoxyglucose 3,5-epimerase SWALL:Q9L6C5 FT (EMBL:AF237894) (202 aa) fasta scores: E(): 4e-34, 50% id FT in 192 aa" FT /db_xref="GOA:Q83NY0" FT /db_xref="HSSP:1DZR" FT /db_xref="InterPro:IPR000888" FT /db_xref="UniProtKB/TrEMBL:Q83NY0" FT /protein_id="CAD66725.1" FT /translation="MELRNLKVNGCLEVTPEVHVDSRGSFSEVYRFDVLEKEIGYPLRV FT AQVNRSFSKKAVLRGLHYSLAPHSQAKYVMCANGAVLDFVFDLRLGSPSFGVWDAVLLD FT SVGCRAVYIPEGVGHAFIALSKTATVNYLCSATYDPEREKSINPLDKNLNLEYPFTTPE FT IVLSERDAAAPTLPEAQKGGFLPKWDECRWDECRATPETHGNIR" FT misc_feature 31898..32426 FT /note="dTDP-4-dehydrorhamnose 3,5-epimerase Score = 241.2 FT E-value = 1e-69" FT CDS 32571..33449 FT /transl_table=11 FT /locus_tag="TW036" FT /product="putative nucleotidyl transferase" FT /note="Similar to Streptomyces sphaeroides NovV FT SWALL:Q9L9E6 (EMBL:AF170880) (297 aa) fasta scores: E(): FT 6.5e-76, 66.78% id in 286 aa, and to Escherichia coli FT glucose-1-phosphate thymidylyltransferase RffH or b3789 FT SWALL:RFFH_ECOLI (SWALL:P27831) (293 aa) fasta scores: E(): FT 6.6e-69, 59.17% id in 289 aa" FT /db_xref="GOA:Q83IF1" FT /db_xref="HSSP:1FXO" FT /db_xref="InterPro:IPR005835" FT /db_xref="UniProtKB/TrEMBL:Q83IF1" FT /protein_id="CAD66726.1" FT /translation="MKGIILAGGTGSRLWPITKCISKQLMPVYDKPMIYYPLSTLMMAD FT IREILVITTTQDYDQFRRLLGDGGQWGIKLSYAQQLSPGGLAQAFLIGESFIASESIAL FT VLGDNIFHGSGLGTSLRQHRSIQGALIFAYHVSNPKDYGVVTFDADGKAVSIEEKPESP FT KSNFAVPGLYFYDNQVVDIAKQIPLSARGELEISSVNNFYLEKDQLRVYPLARGTSWLD FT TGTFDSLVQASEYVRVIEQRQGFKVGCVEEIAWRAGWIDDDQLAKLANGLMKSGYGKYL FT HYLLSGKHGFS" FT misc_feature 32574..33285 FT /note="Nucleotidyl transferase Score = 311.9 E-value = FT 5.3e-91" FT CDS complement(33457..34305) FT /transl_table=11 FT /locus_tag="TW037" FT /product="putative glycosyl transferase" FT /note="Similar to Mycobacterium smegmatis FT dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, FT a-3-L-rhamnosyl transferase WbbL SWALL:Q9RN50 FT (EMBL:AF187550) (296 aa) fasta scores: E(): 2.3e-30, 36.66% FT id in 270 aa" FT /db_xref="GOA:Q83IF0" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q83IF0" FT /protein_id="CAD66727.1" FT /translation="MTMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSH FT DRSICKDYARQFGARFIALEKNSGYGAAVNAGAKRLPSNIEYIGICNPDLALEKGTIST FT LLSVFEQDKDAVAAGPCILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRSYTQ FT SALGTKRRTCGWLSGAFFIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAK FT VKHIGRYSTRQNPKTMLFFHHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKL FT K" FT misc_feature complement(33732..34284) FT /note="Glycosyl transferase Score = 72.8 E-value = 5e-19" FT CDS complement(34302..35108) FT /transl_table=11 FT /locus_tag="TW038" FT /product="putative ABC transport ATP-binding subunit" FT /note="Similar to Myxococcus xanthus O-antigen export FT system ATP-binding protein RfbB SWALL:RFBB_MYXXA FT (SWALL:Q50863) (437 aa) fasta scores: E(): 2.3e-30, 48.92% FT id in 233 aa" FT /db_xref="GOA:Q83IE9" FT /db_xref="InterPro:IPR002198" FT /db_xref="UniProtKB/TrEMBL:Q83IE9" FT /protein_id="CAD66728.1" FT /translation="MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHN FT RSIKERLLNFRVSRANREPFWALKNITFELPIGSSVGLVGHNGSGKSTLLKLIGGIVRA FT TEGEILSRGRISALIELGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFSGIE FT KFIDTQVKFYSSGMYMRLAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEG FT RSIVMVSHVAEQIETVCDKVMVLKNGRLIYYGTTKVGLDLLRENYQ" FT misc_feature complement(34367..34877) FT /note="ABC transporter Score = 129.9 E-value = 3.3e-36" FT misc_feature complement(34833..34856) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(35160..36041) FT /transl_table=11 FT /locus_tag="TW039" FT /product="putative ABC transport integral membrane subunit" FT /note="Similar to Pseudomonas aeruginosa membrane-spanning FT domain Msd Wzm SWALL:P72162 (EMBL:U63722) (265 aa) fasta FT scores: E(): 8.6e-21, 30.68% id in 277 aa, and to FT Myxococcus xanthus O-antigen export system permease protein FT RfbA SWALL:RFBA_MYXXA (SWALL:Q50862) (260 aa) fasta scores: FT E(): 1.2e-15, 26.83% id in 272 aa" FT /db_xref="GOA:Q83NX9" FT /db_xref="InterPro:IPR000886" FT /db_xref="UniProtKB/TrEMBL:Q83NX9" FT /protein_id="CAD66729.1" FT /translation="MPENLIRARLLSKPLKPVGETGMSSLKGMWQRRALLSLLIQREIK FT IRYKGTAFGVLWSMARPIVQLLVYYFAIGKILGAERGIDQFAIFIFVGFATWSLFAEIA FT STAVVCMTNNGGLIKKIYLPRELFVVTALGNALFTFSIYILILMVAAPVLGQMPIDPTK FT WQGFVGIGIAIVYATALGLVLAPLNVYMRDAQHFLDVALSILFWLTPIVYSFQRVNGAV FT HSNIAEQLYLLNPMAIAVMGMQKTFWTAGSSVHWPADIDARLIIVFLVGLLLLFLAHRI FT FVKMQANLAQEL" FT misc_feature complement(35174..35966) FT /note="ABC-2 type transporter Score = 151.4 E-value = FT 1.1e-42" FT misc_feature complement(order(35193..35252,35394..35453,35472..35540, FT 35583..35651,35712..35780,35823..35891)) FT /note="6 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 51-73, 88-110, 131-153, FT 168-190, 197-216 and 264-283" FT CDS 36116..37087 FT /transl_table=11 FT /locus_tag="TW040" FT /product="putative glycosyl transferase" FT /note="Similar to Actinobacillus actinomycetemcomitans DNA FT for glycosyltransferase, lytic transglycosylase, FT dTDP-4-rhamnose reductase SWALL:O05379 (EMBL:AB002668) (289 FT aa) fasta scores: E(): 3.2e-17, 30.73% id in 257 aa" FT /db_xref="GOA:Q83IE8" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q83IE8" FT /protein_id="CAD66730.1" FT /translation="MGVSVVMATYNGGPFLAEQLMSILSQTVLPDEIVIADDGSTDDTE FT RIIFRFRGKFPNLLYIPSEGTRLGPGKNFERAIKRSSQEFIVFSDQDDIWQPDRIEIQQ FT SALKSNPGAVLLHSNARLVDQDGNMLGDLFSALGITKTILTRINNGEAFNILLRRNVVT FT GATVMTRREFALSTLPFPDAWLHDEWLAICGGNRVRVLDHCLIQYRQHDKNHIGARRLS FT VREKFLKLFEDTDVRNARLLARTEALTNFAEEKSGNIFFNTREIGLIRKKLTHERFRST FT LGKSRLLRIWPVLKRVSRYRQFSNFSADILRDLLSSRQHDKP" FT misc_feature 36125..36602 FT /note="Glycosyl transferase Score = 115.3 E-value = FT 8.3e-32" FT CDS complement(37195..37551) FT /transl_table=11 FT /locus_tag="TW041" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX8" FT /protein_id="CAD66731.1" FT /translation="MTSYFFGILVSIALLVILIEMLRREKLRERHAVWWLLAGFIAVFF FT AVFPGILRWISNLLGIITPINLVLFMAVILLFLVCLQQSCELAKLDKRTRRLAEDTLLL FT QDELEDIKSHSSKE" FT misc_feature complement(order(37309..37377,37387..37455,37489..37542)) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 4-21, 33-55 and 59-81" FT CDS complement(37548..38276) FT /transl_table=11 FT /locus_tag="TW042" FT /product="putative glycosyl transferase" FT /note="Similar to Actinobacillus actinomycetemcomitans FT putative glycosyltransferase SWALL:Q9AQB2 (EMBL:AF213680) FT (234 aa) fasta scores: E(): 6.3e-16, 28.99% id in 238 aa" FT /db_xref="GOA:Q83IE7" FT /db_xref="InterPro:IPR001173" FT /db_xref="UniProtKB/TrEMBL:Q83IE7" FT /protein_id="CAD66732.1" FT /translation="MTNRVLVVVPAHNEALSLPGTLQEIKENLPGFSVLVIDDGSTDAT FT SDAAEAHSIKVIRIPFNAGVGGAMRLGFRFALRKGFNVVVQVDADGQHNPKYVSELINR FT LNNRHDKPDIVIGARFAGCGNYKLRGPRRWAIFALSKLMSRFAKTNLTDVTSGFRASGT FT RAIKLFAEKYPTEYLGDTVESVAIALKEGLVVRQVPVAMRERKAGTPSHGPCRATLLLL FT RVVVAALVAPLKSGKSKGCR" FT misc_feature complement(37772..38261) FT /note="Glycosyl transferase Score = 75.8 E-value = 6.5e-20" FT CDS 38634..40475 FT /transl_table=11 FT /locus_tag="TW043" FT /product="putative large integral membrane protein" FT /note="No significant database matches" FT /db_xref="InterPro:IPR018674" FT /db_xref="UniProtKB/TrEMBL:Q83NX7" FT /protein_id="CAD66733.1" FT /translation="MRMSDSDTNSIPLTRSALRKIEKSSAAGASGLRRLRLAVLVPLLL FT FISLAGWALSSPIGSSPDDDFHLASAWCALGDRPGLCESSGIKDAKKVPTTILDTWHGK FT GSRHGNLYCFLNGVSPECQNKWLGNTDHKMQDTGRVNFGNNAQYTNLYYSAMGLLASDD FT VRASVWGMRLINAFIFTALSLLLYLALPQPRRAALLITWSLSLVPAAMFFIPSSNPSSW FT AFIGVPSTFFAMLSFFETRGRRKICLGIIAVFSVLLSAFARSDAAIYALLAIVISGILQ FT VRDFKNPWAQFALPVALGIMSIATFFMYPLNVAATGLPATGARDYGFITFVKNIIFIPS FT SFLPSVFTPQFLGWLDVPLYPPAYVFVAIAALIVVGFALGVGGVRKLFAVLLTLAALII FT APLYVSQVAGITADKLLQPRYLAPLAIIFIAVVLYTGFGEVLQIKKRYMAVIFFLIAPA FT NAFGIFSLLRHYDALPSFLGGALPPTSDGPNAGASRDALAGHHPPGSISAPDGAGTSGE FT HSGSWWWPGFPVSPILLFSVVVASFTLALLIALRDVLKIRNEVNIANETEKALARARRL FT SVSDTPALVNVGTGMITLSKISNATASITLEDAEDQS" FT misc_feature 38634..38813 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.978) with cleavage FT site probability 0.865 between residues 60 and 61" FT misc_feature order(38742..38810,39135..39203,39222..39275,39288..39347, FT 39381..39449,39507..39575,39609..39677,39720..39779, FT 39792..39860,39888..39956,39975..40043,40215..40283) FT /note="12 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 37-59, 168-190, 197-214, FT 219-238, 250-272, 292-314, 326-348, 363-382, 387-409, FT 419-441, 448-470 and 528-550" FT repeat_region 40470..40740 FT /note="rep11. Degenerate repeat sequence including upstream FT and 5' region of CDS." FT CDS 40712..40825 FT /transl_table=11 FT /locus_tag="TW044" FT /product="hypothetical protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83IE6" FT /protein_id="CAD66734.1" FT /translation="MKGNHVMHAPGNAVKTFDPEGCLYGASSGAVGGFDLV" FT CDS 40845..40934 FT /transl_table=11 FT /locus_tag="TW045" FT /product="putative small membrane protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX6" FT /protein_id="CAD66735.1" FT /translation="MALFVVITLLIGAGLFLLRDLLLPGDEQI" FT misc_feature 40848..40901 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 2-19" FT CDS 41326..41835 FT /transl_table=11 FT /locus_tag="TW046" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX5" FT /protein_id="CAD66736.1" FT /translation="MQKTHPYNMYMFGEIFKQRALEVKRSIGQMPRLPRACFIATPPLV FT LVKMVILVTLWSFWWMWPILFSIIAIDWAVSAVGVFSARRWAKHNPDKLLNLKWAVYPF FT VFIIALFAFIRPFLLMGGYILLMFFALPIGGMIRMFALLAIMSGAKPKPISMLRRAIKG FT RKKRDL" FT misc_feature order(41422..41490,41500..41568,41605..41667,41695..41763) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 33-55, 59-81, 94-114 and FT 124-146" FT repeat_region 42022..42288 FT /note="rep11. Degenerate repeat sequence including upstream FT and 5' region of CDS." FT CDS 42189..42587 FT /transl_table=11 FT /locus_tag="TW048" FT /product="putative secreted protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX4" FT /protein_id="CAD66737.1" FT /translation="MKKLTTVSITVLSIVTLLFIAQPAQASEGNLEANQGTKLKRVTRS FT VKTFDVDKCLNGAVSGAVGVGGGFAGAQAAKLIIKGVSAVNPATFAAVTAGTAVADCVM FT HGGLVDDVVNGFNAGFNAVGDFIGKLFG" FT misc_feature 42189..42266 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.996 between residues 26 and 27" FT CDS 42584..42982 FT /transl_table=11 FT /locus_tag="TW049" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX3" FT /protein_id="CAD66738.1" FT /translation="MNASTLGGRLKNSRLFIVACMLLLIPLFIYVVLSGYSLGYAFGAA FT LALAFTCPGVVRSVFNGSFSLDLGNPFLAAIGLLGAGYLILMTLSPVLWLLFSQTFMFY FT FNAVMFTMLFVALQCALARWAVLSRRAG" FT misc_feature 42584..42730 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.992) with cleavage FT site probability 0.533 between residues 49 and 50" FT misc_feature order(42626..42682,42695..42763,42806..42874,42893..42961) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 15-33, 38-60, 75-97 and FT 104-126" FT CDS 43109..43420 FT /transl_table=11 FT /locus_tag="TW051" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX2" FT /protein_id="CAD66739.1" FT /translation="MDSQQIGLNNFVLRNLLLGFVATVCILFPIAFVLVAGRDWHAVPL FT VFVVLMAICPLFIFDYRFVSGKFKVIVGLSWAAAIFFCAFTILTGIAFLFFGFPDISH" FT misc_feature 43109..43213 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.706) with cleavage FT site probability 0.437 between residues 35 and 36" FT misc_feature order(43145..43213,43226..43285,43322..43390) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35, 40-59 and 72-94" FT repeat_region 43618..43884 FT /note="rep11. Degenerate repeat sequence including upstream FT and 5' region of CDS." FT CDS 43784..44215 FT /transl_table=11 FT /locus_tag="TW052" FT /product="putative secreted protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX1" FT /protein_id="CAD66740.1" FT /translation="MKKLTTVSITVLSIVTLLFIVQPAQARGGAGHISVVARGGNTYIT FT ATIREGFDLDECLKGAVTEVFDVGTGSHMGFLGRLVKIVVKGARFAGPIGTAIGTSIDV FT ITGCLKQGIVPDKPQIPHVNSVCTVNIFSHRPGHSCYKR" FT misc_feature 43784..43861 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.947 between residues 26 and 27" FT misc_feature 43802..43861 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-26" FT CDS 44219..44608 FT /transl_table=11 FT /locus_tag="TW053" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NX0" FT /protein_id="CAD66741.1" FT /translation="MARITRNTSVPVLILCCLLSIPLLAIVGVILVLAGSELWFIPAFV FT LFLMFIFGPEHHVTDYNLWEALFAGLIMGGSLAMLTTCSVVNFVYPELWLLRSPGFSIA FT CTVAFAIAAAFFLAVDLRRKIKQGQ" FT misc_feature 44219..44320 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.997) with cleavage FT site probability 0.402 between residues 34 and 35" FT misc_feature order(44252..44320,44330..44383,44420..44488,44516..44575) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 12-34, 38-55, 68-90 and FT 100-119" FT repeat_region 44676..44810 FT /note="(tcgaatcgtgctgta)9" FT CDS complement(44860..46251) FT /transl_table=11 FT /locus_tag="TW054" FT /product="putative two component system sensor kinase" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein Rv0758 or mt0783 or mtcy369.03 SWALL:P71815 FT (EMBL:Z80226) (485 aa) fasta scores: E(): 8.9e-37, 31.11% FT id in 466 aa, and to Streptomyces coelicolor putative two FT component system histidine kinase SCO4021 or 2SC10A7.25 FT SWALL:Q9ADN6 (EMBL:AL583945) (524 aa) fasta scores: E(): FT 5.5e-27, 37.73% id in 265 aa" FT /db_xref="GOA:Q83IE5" FT /db_xref="InterPro:IPR003660" FT /db_xref="UniProtKB/TrEMBL:Q83IE5" FT /protein_id="CAD66742.1" FT /translation="MVTLVALVLAFSFTAVGIGTTLVIKNEMIKTIDEQLIHISGTFPL FT FESSFEVFSPGRASYKAHIYKFDGTLIWPIGENPSIEFDRKIDITLYNEKGNTPFTLHS FT ISRQKKYRMLLQPLETGSGQEILAYYLPQSGTENTANFYQRSYIWFSLAVFAIAAYIVY FT LITAHTLSPLYALEKTARAFARGDYSRRIRSEYVSAEILNLNKSLNSMLDSLEKALGER FT DKTLGEMKQFLADASHELRTPLVSLRGYAELYRIGALKGKEDIDNAIERIEKEAIRMGT FT MVEDLLSLTRLEKATDLVPVDVKYLVQESVIDMNVLEKTRKITTGIPKRQSCMILGNEN FT MLRRLLANLINNALHYTPPGSPIEIVLRTDKTDVVIDVRDHGPGVPRQLHDKVFKRFWR FT SDASRARNSGGVGLGLSIVASIVKVHKGTIEILRTRGGGATFRTRIPKLVNKHRSGSSS FT HSLTR" FT misc_feature complement(44910..45243) FT /note="Histidine kinase-, DNA gyrase B-, and HSP90-like FT ATPase Score = 132.6 E-value = 5.2e-37" FT misc_feature complement(45369..45570) FT /note="His Kinase A (phosphoacceptor) domain Score = 68.2 FT E-value = 1.2e-17" FT misc_feature complement(45603..45813) FT /note="HAMP domain Score = 46.4 E-value = 4.5e-11" FT misc_feature complement(order(45742..45810,46180..46239)) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-24 and 148-170" FT misc_feature complement(46177..46251) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.702) with cleavage FT site probability 0.385 between residues 25 and 26" FT CDS complement(46318..47001) FT /transl_table=11 FT /locus_tag="TW055" FT /product="putative two component system response regulator" FT /note="Similar to Streptomyces coelicolor putative two FT component system response regulator SCO4020 or 2SC10A7.24 FT SWALL:Q9ADN7 (EMBL:AL583945) (271 aa) fasta scores: E(): FT 1.2e-40, 50.44% id in 226 aa" FT /db_xref="GOA:Q83NW9" FT /db_xref="HSSP:1B00" FT /db_xref="InterPro:IPR001867" FT /db_xref="UniProtKB/TrEMBL:Q83NW9" FT /protein_id="CAD66743.1" FT /translation="MSQTKILVVDDEANIRDLLAASLRFAGYGVVTAGNGAGAVSAVLA FT EEPDLIIMDVMLPDMSGFAATKRLREAGFRCPVIFLSARDSTEDKITGLTVGGDDYVTK FT PFSLDEILARVAAILRRTKIDDVDATIRVGDLVIDQNSNEVFLKGNLIDLSPTEFKLLR FT YFMLNPNRVLSKSQILGHVWDYDFDGDSSIVESYISYIRRKLAAYSSETIIHTKRGFGY FT IMRTR" FT misc_feature complement(46332..46557) FT /note="Transcriptional regulatory protein, C terminal Score FT = 88.7 E-value = 8.6e-24" FT misc_feature complement(46635..46992) FT /note="Response regulator receiver domain Score = 141.1 FT E-value = 1.4e-39" FT CDS 47266..47643 FT /transl_table=11 FT /locus_tag="TW057" FT /product="cold shock protein B" FT /note="Similar to Streptomyces coelicolor cold shock FT protein B CspB or SCO4325 or SCD12A.08 SWALL:Q9KXN2 FT (EMBL:AL357524) (127 aa) fasta scores: E(): 8.1e-16, 42.06% FT id in 126 aa, and to Pseudomonas fragi cold shock protein FT CapB SWALL:CAPB_PSEFR (SWALL:P80415) (69 aa) fasta scores: FT E(): 0.0014, 38.09% id in 63 aa" FT /db_xref="GOA:Q83NW8" FT /db_xref="HSSP:1MJC" FT /db_xref="InterPro:IPR011129" FT /db_xref="UniProtKB/TrEMBL:Q83NW8" FT /protein_id="CAD66744.1" FT /translation="MPLGTVRFYNKERGFGFVVSDDGESVFLPAKALPDGVSDLSPGTR FT VDYGAALGKKGSQVLSLRVLRKPPRRGVRSTDDMAVIIEDLMKILDEAGESFKRGRYPK FT AERAKVLAAMLRQVADGLDAN" FT misc_feature 47266..47458 FT /note="'Cold-shock' DNA-binding domain Score = 23.9 E-value FT = 1.1e-05" FT CDS 47741..47968 FT /transl_table=11 FT /locus_tag="TW058" FT /product="hypothetical protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83IE4" FT /protein_id="CAD66745.1" FT /translation="MRYVNLTCGYTGWFWIAAVNKTADGDLNVLELYPSPGPGALAFTA FT RSDQIATGGEYDDDESGDLITPVDRDGLDF" FT CDS 47971..48753 FT /transl_table=11 FT /locus_tag="TW059" FT /product="putative sporulation/chromosome partition FT protein" FT /note="Similar to Streptomyces coelicolor putative FT partitioning or sporulation protein SCO1772 or SCI51.12c FT SWALL:Q9S228 (EMBL:AL109848) (340 aa) fasta scores: E(): FT 9.9e-52, 57.14% id in 252 aa, and to Bacillus subtilis FT sporulation initiation inhibitor protein Soj FT SWALL:SOJ_BACSU (SWALL:P37522) (253 aa) fasta scores: E(): FT 2.6e-38, 46.21% id in 251 aa" FT /db_xref="GOA:Q83NW7" FT /db_xref="InterPro:IPR002586" FT /db_xref="UniProtKB/TrEMBL:Q83NW7" FT /protein_id="CAD66746.1" FT /translation="MTKKSARTVAVCNQKGGVGKTTTTINLAACLAERGMRVLTVDLDP FT QGALTAGFGISNFEYTVYDLLLGRNRNAVLIQTSLKGVDVLPANIDLSAAEVYLVSEVA FT REQILAKELESFSSDYDVILIDCQPSLGLLTINALTASHGLLIPLECEYFAMRGLALLL FT ETVRKIQDRLNTALKVDGIIATMFDMRTLHAREVLESVKKAFPGLLLTTVINRTIKFPD FT SSIAGMPVTVFAPNHQASKNYRDLTHELVHRGVFTLPS" FT misc_feature 48223..48556 FT /note="ParA family ATPase Score = 119.9 E-value = 3.4e-33" FT CDS 48827..49963 FT /transl_table=11 FT /locus_tag="TW060" FT /product="putative oxidoreductase" FT /note="Similar to Staphylococcus aureus prephenate FT dehydrogenase TyrA or Mw1252 SWALL:BAB95117 (EMBL:AP004826) FT (363 aa) fasta scores: E(): 8.9e-10, 27.5% id in 389 aa" FT /db_xref="GOA:Q83NW6" FT /db_xref="InterPro:IPR003099" FT /db_xref="UniProtKB/TrEMBL:Q83NW6" FT /protein_id="CAD66747.1" FT /translation="MYVHIIGAGLIGGSIALGLSRAGLKVSASDISPAAQRLSKLGDIS FT IGPPNQNPDLVFVCTPPDVTAAEVVSSLDRFPETCVVDVSSVKTRIYREVLRKTHPAKR FT VFYIQSHPMAGREIGGIQGASADLFSGWPWIVCHSFVCGDGNDQMNGENSVHQKNYLTR FT NTEDEAEWSLGKNLLHCINLLGAFPVFMDRDRHDRSVAAVSHVPHILSSLIALSLANTD FT QGTVAICGSGIKDMTRLAASNPELWTQIIFSNRREILQSLGVFSGLLKRMLHTLEKLDN FT PAYRTDLFSQLAEAQAQQARIPKKPGKNLDYSQLEVLIPDKPGELSKVLGAINTQGINL FT EDLHFEHANNLGVVKLSVSNKDRCRLMDTLEDKWTLLV" FT misc_feature 48839..49721 FT /note="Prephenate dehydrogenase Score = 124.4 E-value = FT 1.5e-34" FT misc_feature 49763..49856 FT /note="ACT domain Score = 19.1 E-value = 4.5e-05" FT CDS 49945..52005 FT /transl_table=11 FT /locus_tag="TW061" FT /product="putative GTP-binding protein" FT /note="Similar to many eg. Streptomyces coelicolor putative FT GTP binding protein SCO1758 or 2SCI34.11c SWALL:Q9EWW8 FT (EMBL:AL445403) (492 aa) fasta scores: E(): 8.6e-84, 49.49% FT id in 493 aa. N-terminal region contains match to Pfam FT PF02224 Cytidylate kinase." FT /db_xref="GOA:Q83NW5" FT /db_xref="HSSP:1MKY" FT /db_xref="InterPro:IPR016484" FT /db_xref="UniProtKB/TrEMBL:Q83NW5" FT /protein_id="CAD66748.1" FT /translation="MDFTSIVAIDGPAGSGKSSVGRAVAQYLGYGFLPTGSYYRAFAFL FT LDQTKDLDSQLDSFISSVRNDLDPYNSGFNVHIDDSPFFGSSGISASSRNIASELNNPE FT ITSKTAAVARNKSVRVRLNEYFRKLCSESIYPAIVLEGRDATTVIAPNARVKIFLTASL FT VKRAARRSEQLSSEPPNSVLEALRQRDEADNAVTDFLSDDSSRITLDTSDLTFSESVAR FT VLEVIEQAGMPFVSDKWVGENADVLAASGELGATVVIVGRPNVGKSALVNCILGRREAV FT VENRPGVTRDRVVYPAFWAGRPFTLVDTGGWECDAEGLDAEVVAQAEIGMSIADIIIFV FT VDVQHGPVSTDAVIARNLQRQNKPIFLVANKADNASSDSDVAQFWSLGLGQPYACSATH FT GRGVADLMDIVMQSAQVHTPSFCSGAPRVALIGRPNVGKSSLINQLTNSRRAIVDDLAG FT TTRDPLDALAVIGDKSWLFVDTAGLRRKFKSQKGADFYAYLRATTVLRRTEIALLLLDA FT SHAITEQDVRIAEMVVESGRALVIAINKWDLLDEERRYWLEREIDNTFFRFAWAPRVNI FT SARTGRGVKQLATALQTALTNWNTRLNTARVNHFLQRITREQPHPTRGGRRPRILFASQ FT TGVAPPTFTLFTTGFLEPTYRRFLQKSIRSQHSFTGSPIILSVKIRASRNR" FT misc_feature 49975..49998 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 50152..50617 FT /note="Cytidylate kinase Score = 66.2 E-value = 4.8e-17" FT misc_feature 50725..50748 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 50911..51682 FT /note="GTPase of unknown function Score = 158.0 E-value = FT 1.2e-44" FT misc_feature 51238..51261 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(52002..53279) FT /transl_table=11 FT /locus_tag="TW062" FT /product="putative chorismate binding enzyme" FT /note="Similar to Pseudomonas putida anthranilate synthase FT component I TrpE SWALL:TRPE_PSEPU (SWALL:P20579) (493 aa) FT fasta scores: E(): 5e-16, 29.18% id in 281 aa" FT /db_xref="GOA:Q83NW4" FT /db_xref="HSSP:1K0E" FT /db_xref="InterPro:IPR015890" FT /db_xref="UniProtKB/TrEMBL:Q83NW4" FT /protein_id="CAD66749.1" FT /translation="MLPIEVEITRIGNMDRSDFKRQYIRKVLSWDFVYCTHSTMMRTQG FT RVLKINLDSYSAEARFEAAESLINEIHTKIQYTSENLNPIGLIVLFGFTFSPYSARPSF FT LAIPEQMFFWSDGVAWKIDATICHNLSEPSRIFKWPKSISFKMGDFRQEDYKHAITNVV FT NKLLNADISKVVLARDIIAEIHDDFDPEAHAIDLDEAIQRLMNTANGTVFVFDGLFGAS FT PEVLLRTDGNSGFEVSILAGSMSANHPKHVIHNCAASPPYKALDETYLDEKLRLEHSFA FT LNPTLERLSTLMNTAPTVNSYKIRRFTHITHVASFISGTFKPNISPLRALSHIHPTGAI FT AGEPRERALEIIKEIEPFDRELYGGAIGWIGQDSSCEFTLPIRCAQLNRGHIKAFAGCG FT IVKSSIPQKELEESTLKFKTIIDAIS" FT misc_feature complement(52010..52829) FT /note="chorismate binding enzyme Score = 42.5 E-value = FT 1.2e-18" FT CDS 53375..54094 FT /transl_table=11 FT /locus_tag="TW063" FT /product="putative ubiquinone/menaquinone FT methyltransferase" FT /note="Similar to Streptomyces coelicolor putative FT ubiquinone/menaquinone methyltransferase SCO4556 or FT SCD16a.27c SWALL:Q9XAP8 (EMBL:AL078618) (231 aa) fasta FT scores: E(): 1.6e-29, 42.17% id in 230 aa, and to FT Escherichia coli, and Escherichia coli O157:H7 FT ubiquinone/menaquinone biosynthesis methyltransferase UbiE FT or b3833 or z5355 or ecs4763 SWALL:UBIE_ECOLI FT (SWALL:P27851) (251 aa) fasta scores: E(): 6.5e-23, 36.32% FT id in 245 aa" FT /db_xref="GOA:P67065" FT /db_xref="InterPro:IPR004033" FT /db_xref="UniProtKB/Swiss-Prot:P67065" FT /protein_id="CAD66750.1" FT /translation="MGTNIHIDMVIHGKHTAEIRKMFNRVAQAYDRTNLVLSFLQDAHW FT RRAACKMLGVTAGEEVLDVGAGTGASTRTVARTGAAVTGIDISPRMLQIARNRCKRFQN FT ITWRLTNGDLPFPDKSFDAILMVFCLRNVSNIQGFLCDAARVLKPGGRLVVCEFSHPRR FT FVAPFYRLYLRYVLPRLAKLISSDPAAYEYLTESIEDWYEVDELAFMLEQCGFQNTSWK FT RLSFGAVALHRALRGPE" FT misc_feature 53396..54080 FT /note="ubiE/COQ5 methyltransferase family Score = 136.3 FT E-value = 3.8e-38" FT CDS 54106..55122 FT /transl_table=11 FT /locus_tag="TW064" FT /product="putative polyprenyl diphosphate synthase" FT /note="Similar to Streptomyces coelicolor putative FT transferase SCO4583 or SCD20.01 SWALL:Q9F2X8 FT (EMBL:AL392148) (336 aa) fasta scores: E(): 3.3e-37, 38.19% FT id in 343 aa, and to Gluconobacter oxydans decaprenyl FT diphosphate synthase DdsA SWALL:O82832 (EMBL:AB006850) (315 FT aa) fasta scores: E(): 2.4e-23, 32.55% id in 301 aa" FT /db_xref="GOA:Q83NW3" FT /db_xref="InterPro:IPR017446" FT /db_xref="UniProtKB/TrEMBL:Q83NW3" FT /protein_id="CAD66751.1" FT /translation="MLVSGIFLSDILDPSGSLSDDISPALDRVEDLLLETVGDCHEIVS FT HLLVSGGKRARPLLVLLTSCMGSGINDAVIRAAAGIELIHLGSLYHDDVMDNAYIRHGS FT ITAHRLWGKSAAILAGDFLFAKAGVLGLNLDKRAIAVQTEAFQRMISGQLSETLGISDS FT LDPLEAYIEVSRGKTGSLIAASAQVGAILGDASLSTLEPLRDFGESIGVAFQLVDDVID FT LSGKSGKTPGSDIRAGVMSLPILLLSNAAKDDRDSAVLLEEIERVRRHSGACGSDDYSS FT EMNAVLAHLRKHDVTARTLEIARTWGDKAKHALKKLPECAPRDALLAFVETVVSREF" FT misc_feature 54223..54985 FT /note="Polyprenyl synthetase Score = 137.2 E-value = FT 2.2e-38" FT misc_feature 54424..54447 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 54733..54771 FT /note="PS00444 Polyprenyl synthetases signature 2." FT CDS 55141..56484 FT /transl_table=11 FT /locus_tag="TW065" FT /product="putative ferredoxin/ferredoxin-NADP reductase" FT /note="Similar to Streptomyces coelicolor putative FT ferredoxin/ferredoxin-NADP reductase SCO0681 or SCF15.02 FT SWALL:Q9RK35 (EMBL:AL132856) (454 aa) fasta scores: E(): FT 1.3e-71, 43.55% id in 450 aa, and to Rattus norvegicus FT NADPH:adrenodoxin oxidoreductase, mitochondrial precursor FT FdxR SWALL:ADRO_RAT (SWALL:P56522) (494 aa) fasta scores: FT E(): 7.4e-33, 35.16% id in 455 aa" FT /db_xref="GOA:Q83NW2" FT /db_xref="HSSP:1LQT" FT /db_xref="InterPro:IPR013027" FT /db_xref="UniProtKB/TrEMBL:Q83NW2" FT /protein_id="CAD66752.1" FT /translation="MARIAVVGAGPAGIYSANLLLADESVERVDVFEALPAPYGLVRYG FT VAPDHPRIKSVVSTLSDMLETPRMRLFCGVHFGQHLSLEDIKQRYNAVIFATGALRGAR FT LDIPGIDARNSFSAADFVAWYDGHPDYPRTWPLSAKSVGIIGNGNVALDIARILVKQPE FT ELETTEIPDNVYEDLKSSALSDVHIFGRRGPFDVKFTPLELRELGEVNGVDIVLNEDDF FT QVKPDRLVKQMIIIDRVFSSWRARSGTSSTRRLHFHFYSVPKRVVVRDNCVSGLEYQQL FT RPTIDACDCVAPPRDSDTRHEVVELDALYTAIGYYGSPLSDLPFDDISGIIPNDRGRVI FT IEGKPLRGCYVTGWIKRGPVGLIGHTKSDAIETIVSMRQDKTAWWKPDTDSDISDLLGS FT RGVNFTGVSGWRKLDAHEIYLGSLSGKTRKKVVPREEMYYISSRGSPS" FT CDS complement(56824..57795) FT /transl_table=11 FT /locus_tag="TW066" FT /product="putative iron-siderophore binding lipoprotein" FT /note="Similar to Streptomyces coelicolor putative FT iron-siderophore binding lipoprotein SCO0494 or SCF34.13c FT SWALL:Q9RK12 (EMBL:AL109974) (350 aa) fasta scores: E(): FT 7.7e-19, 30.97% id in 339 aa, and to Corynebacterium FT diphtheriae DtxR/iron regulated lipoprotein precursor Irp1 FT SWALL:Q46023 (EMBL:U02617) (355 aa) fasta scores: E(): FT 1e-12, 31.02% id in 303 aa" FT /db_xref="GOA:Q83IE3" FT /db_xref="InterPro:IPR002491" FT /db_xref="UniProtKB/TrEMBL:Q83IE3" FT /protein_id="CAD66753.1" FT /translation="MFGRKLLGALVALSLLTGCFGGKGDSESSSVLSKVETVFGEVTIP FT RPKGHDLRVVALGWSDAEAALAVGIKPVAVYDWISFGNKGVGPWAEGLFGDVKPEVISR FT GTDGLNWEQIHNLKPDLILNVRSNNDEKTYKRLSQIAPTVYGPPGTKSWVLNWRDQQRQ FT VAKALGRVKEGEEAIKKTEKAIKDAQDPLYRGLKGAFVAKFAEYGVYLPGDGRWDLMQE FT LGFTLEPKINELPKAGFYAKIPTDKLSWVDTDVLIVISIGTDDITKDALLSSLKAAKEG FT RVIYANKDLANVLSASSALSIREAIKRISDKLREIAKKLRNK" FT misc_feature complement(56928..57651) FT /note="Periplasmic binding protein Score = 83.8 E-value = FT 2.5e-22" FT misc_feature complement(57718..57795) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.630 between residues 26 and 27" FT misc_feature complement(57739..57771) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS complement(57921..58916) FT /transl_table=11 FT /locus_tag="TW067" FT /product="putative iron-siderophore binding lipoprotein" FT /note="Similar to Streptomyces coelicolor putative FT iron-siderophore binding lipoprotein SCO0494 or SCF34.13c FT SWALL:Q9RK12 (EMBL:AL109974) (350 aa) fasta scores: E(): FT 4.2e-19, 29.82% id in 342 aa, and to Mycobacterium FT smegmatis FxtD SWALL:O87315 (EMBL:AF027770) (420 aa) fasta FT scores: E(): 2.7e-12, 31.09% id in 238 aa" FT /db_xref="GOA:Q83IE2" FT /db_xref="InterPro:IPR002491" FT /db_xref="UniProtKB/TrEMBL:Q83IE2" FT /protein_id="CAD66754.1" FT /translation="MFGRKLLGALVALSLLTGCFGGKGDSESSSVLSKVETVFGEVTIP FT RPKGHDLRVVALGRADAEAALAVGIKPVAVLDAFNIGGKGVGPWAEGLFGDVKPTVMSF FT STDGLNWEQIKAFKPDVILDVRSKNDEKTYKRLSQIAPTVYGPKNSKDYQPYQIPWRDQ FT QRQVAKALGRVKEGEEAIKKTEKAIKDAQDPLYRGLKAALVVQRPSGYGVFAESTRQWD FT LIRELGFTLEPRVTELFDGRHAGKDIPSGKLNLIDTDVIVVTVKRGIRKAANHNDPLIA FT SLKASKEGRIIYGSDEFNLALIAGSVLSIPEAIKFLSDKLREIAKKLRNK" FT misc_feature complement(58025..58772) FT /note="Periplasmic binding protein Score = 81.2 E-value = FT 1.5e-21" FT misc_feature complement(58839..58916) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.630 between residues 26 and 27" FT misc_feature complement(58860..58892) FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS complement(59134..59919) FT /transl_table=11 FT /locus_tag="TW068" FT /product="putative iron-siderophore uptake system FT ATP-binding component" FT /note="Similar to Escherichia coli ferric enterobactin FT transport ATP-binding protein FepC or b0588 FT SWALL:FEPC_ECOLI (SWALL:P23878) (271 aa) fasta scores: E(): FT 8.6e-42, 50% id in 250 aa" FT /db_xref="GOA:Q83IE1" FT /db_xref="HSSP:1L7V" FT /db_xref="InterPro:IPR003439" FT /db_xref="UniProtKB/TrEMBL:Q83IE1" FT /protein_id="CAD66755.1" FT /translation="MITVDKLSFSYGKNKVLHDISIEIKRGSFIAIIGANGCGKSTFLR FT SIAGLNRFEGDILLDKQHIRRLKPKNLAKHIAFLPQQVNLPEGLTIADLVSRGRYPHQS FT ILHRWTKTDEEVVKESLQAVQASHISQRAIEAVSGGQRQRALIAMVLAQQTRILLLDEP FT TTFLDIAYQYEILELLASLNRESKTIICSLHDLNQAARYASHLFVMGEGRIIASGEPKK FT VITENLIENAFGLKSRIIDDPESNTPMIIPRKSENLKRL" FT misc_feature complement(59286..59841) FT /note="ABC transporter Score = 172.0 E-value = 6.8e-49" FT misc_feature complement(59467..59511) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(59797..59820) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(59903..60937) FT /transl_table=11 FT /locus_tag="TW069" FT /product="putative iron-siderophore uptake system integral FT membrane component" FT /note="Similar to Escherichia coli ferric enterobactin FT transport system permease protein FepG or b0589 FT SWALL:FEPG_ECOLI (SWALL:P23877) (330 aa) fasta scores: E(): FT 1.2e-43, 39.93% id in 323 aa" FT /db_xref="GOA:Q83NW1" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q83NW1" FT /protein_id="CAD66756.1" FT /translation="MPQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQ FT TSFADMWSALTGNGDIELRQTILEWRLPRVLSAIFVGSSVALAGALFQSLTRNPLCSPD FT IIGFNAGAFAGVIIAAELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLVIVG FT ISLNAIISSFNTYMKSIINVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIV FT IPKMRVLEMGDDNAASLGVSARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKF FT LVGSKAINIFPTIAVGGFLLAASDLIARTIIAPSQLPTGVVTIVFGGAYLLYLSIRGAN FT DYRR" FT misc_feature complement(59929..60814) FT /note="FecCD transport family Score = 267.8 E-value = FT 9.9e-78" FT misc_feature complement(order(59936..60004,60032..60100,60119..60187, FT 60269..60322,60488..60556,60566..60625,60662..60730, FT 60809..60877)) FT /note="8 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 21-43, 70-92, 105-124, FT 128-150, 206-223, 251-273, 280-302 and 312-334" FT misc_feature complement(60806..60937) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.829) with cleavage FT site probability 0.374 between residues 44 and 45" FT CDS complement(60943..61908) FT /transl_table=11 FT /locus_tag="TW070" FT /product="putative iron-siderophore uptake system integral FT membrane component" FT /note="Similar to Escherichia coli ferric enterobactin FT transport system permease protein FepD or b0590 FT SWALL:FEPD_ECOLI (SWALL:P23876) (334 aa) fasta scores: E(): FT 5.2e-33, 40% id in 305 aa" FT /db_xref="GOA:Q83NW0" FT /db_xref="InterPro:IPR000522" FT /db_xref="UniProtKB/TrEMBL:Q83NW0" FT /protein_id="CAD66757.1" FT /translation="MAGPVFRLSLVFGSVVIVGLCYLALFLDGSSVGQLIDAVFGGGDD FT FKDVVLRDFRVPRILLAILVGAALSVAGAIMQVVTRNPLADPGLLGITHGAYLAIVLGF FT LVGYVTPFWNLLIVPLLGASIAAGLVYFIGNIVTPGQLILVGVALTALISGLARSVALI FT NQDIFDVIRHWAVGSLDYKKIDTVYISFPLILAGILIALMMMSSLNVLSIDKDISKSLG FT VGKTALWSYIAVIALSAGSTAAVGPISFLALAAAHISRVISGPNLLRIIPLCLITGPIV FT LLTADTLGRVLTPTGLDAGVVVPFLGAPILIFLSRKVKVF" FT misc_feature complement(60960..61824) FT /note="FecCD transport family Score = 223.4 E-value = FT 2.3e-64" FT misc_feature complement(order(60967..61026,61054..61113,61150..61218, FT 61276..61344,61417..61485,61498..61566,61579..61647, FT 61675..61743,61828..61896)) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-27, 56-78, 88-110, 115-137, FT 142-164, 189-211, 231-253, 266-285 and 295-314" FT misc_feature complement(61786..61908) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.836) with cleavage FT site probability 0.222 between residues 41 and 42" FT tRNA complement(62075..62151) FT /note="tRNA Met anticodon CAT, Cove score 95.55" FT tRNA complement(62170..62241) FT /note="tRNA Thr anticodon GGT, Cove score 73.84" FT CDS 62354..62647 FT /transl_table=11 FT /locus_tag="TW071" FT /product="putative regulator" FT /note="Similar to Staphylococcus aureus cadmium efflux FT system accessory protein homolog cadC SWALL:CADF_STAAU FT (SWALL:P37374) (121 aa) fasta scores: E(): 3e-07, 37.89% id FT in 95 aa" FT /db_xref="GOA:Q83NV9" FT /db_xref="HSSP:1SMT" FT /db_xref="InterPro:IPR001845" FT /db_xref="UniProtKB/TrEMBL:Q83NV9" FT /protein_id="CAD66758.1" FT /translation="MGLSRKNAQSAEKLFKCLASASRLKILFVLLESEKSVGDITVDCD FT MSQPLVSQHLRHLRDNNLVYTKRHGKQVYYSIADEHIKHVVADCIQHVQHET" FT misc_feature 62396..62627 FT /note="Bacterial regulatory protein, arsR family Score = FT 84.2 E-value = 1.9e-22" FT tRNA complement(62810..62892) FT /note="tRNA Tyr anticodon GTA, Cove score 64.70" FT CDS complement(62943..64580) FT /transl_table=11 FT /gene="lysS" FT /locus_tag="TW072" FT /product="lysyl-tRNA synthetase" FT /EC_number="6.1.1.6" FT /note="Similar to Pyrococcus horikoshii lysyl-tRNA FT synthetase LysS or ph0224 SWALL:SYK_PYRHO (SWALL:O57963) FT (523 aa) fasta scores: E(): 2e-56, 33.2% id in 530 aa" FT /db_xref="GOA:Q83IE0" FT /db_xref="HSSP:1IRX" FT /db_xref="InterPro:IPR001412" FT /db_xref="UniProtKB/TrEMBL:Q83IE0" FT /protein_id="CAD66759.1" FT /translation="MTASRIDAASPEKYGKQDWVSKLAEQVIQERKGDKKIVVASGISP FT SGQIHLGNLREVITGHFIADEISSRGFDCEHILSWDDFDRLRKVPANIDKGYEQYIGMP FT LCDVPPPAGSKKNSWSEHFRGDFEKTMEILGIKVRHISQSQMYRSGAYTHNILLALEKR FT HEIQNIIGKYQSKKTQPAESPREYYPYVVYCTRCKKDLTQIEDFAGSELSYSCKCGHSE FT TIGIGEFNNGKLPWKVDWPMRWMYESVDFEPGGVDHCSPGSASLSASSDIANQIFNWTP FT PLTVMYSFVGVQGHAKMSSSTGNVLTPNDALSVMEPTLLRWMYARRKPNQSFTVGFDQS FT LQRLYDEWDSLPNDLTGCELASSYTRAMSTTNKRFNAPEILISFRTLVSLIDISASDDS FT QLLRMVKNLRPDIRSLAQLEPRLSCARIYSKKFSNPIHVLQTPNKQVLHTAAPNVREML FT RIFIDGLDKNWSIEKLTTLAYGVPKVVLGIDQSSKDVSQEVKNLQKEFFRTIYQLVIGQ FT DKGPRLPTLLMAIGKQSTRALLCSCETC" FT misc_feature complement(62966..64532) FT /note="tRNA synthetases class I (K) Score = 364.7 E-value = FT 7e-107" FT misc_feature complement(64419..64448) FT /note="PS00178 Aminoacyl-transfer RNA synthetases class-I FT signature." FT CDS 64669..65535 FT /transl_table=11 FT /gene="panC" FT /locus_tag="TW073" FT /product="pantoate--beta-alanine ligase" FT /EC_number="6.3.2.1" FT /note="Similar to Corynebacterium glutamicum FT pantoate--beta-alanine ligase PanC or cgl0113 FT SWALL:PANC_CORGL (SWALL:Q9X713) (279 aa) fasta scores: E(): FT 1.5e-27, 39.59% id in 293 aa" FT /db_xref="GOA:Q83ID9" FT /db_xref="HSSP:1N2E" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q83ID9" FT /protein_id="CAD66760.1" FT /translation="MNLKLASSPHELRTCLAGRAFVLVPTMGALHEGHIWLVDMARRCN FT LPVVVSIFVNPLQFDDSLDLDTYPRTLEQDLEKLEGKAFAVYSPSVETMYPNGLDSIRI FT DPGPIGRILEGAIRPGFFDGILTIVAKLLLQTAPERVFFSKKDAQQAFLVRRMVRELAF FT PVRVEVTGFLRDKFSLPYSSRNRKLGVDAREKAQRLSQGLLSVVNNGPLTVRDCIDKIT FT DLANSIGVDLGYAQILDENFCEIASDRMVTRAFHSEACIGLNTPLFLLAARVHGVRVVD FT NVDLVVV" FT misc_feature 64675..65521 FT /note="Pantoate-beta-alanine ligase Score = 171.0 E-value = FT 1.4e-48" FT CDS 65832..67328 FT /transl_table=11 FT /locus_tag="TW074" FT /product="putative phospholipase" FT /note="Similar to Escherichia coli cardiolipin synthetase FT Cls or Nov or b1249 SWALL:CLS_ECOLI (SWALL:P31071) (486 aa) FT fasta scores: E(): 4.9e-21, 30.64% id in 496 aa" FT /db_xref="GOA:Q83NV8" FT /db_xref="InterPro:IPR001736" FT /db_xref="UniProtKB/TrEMBL:Q83NV8" FT /protein_id="CAD66761.1" FT /translation="MKPYLFILAALLLADLVIRIGCLFVVPRNRRPNSANAWLLTIFFL FT PFIGWFLFLIIGSYKLPKSRREKQALINQLVANALSDHAVLDNVDLQWLPSLVKLNRNL FT GSMPMVAGTRVHILTDTSVIMEQMVSAIDSAKSSVHVEFYIFSLDEFTQGFFTSLENAT FT ARGVKVRVLYDHIATLRVPGYLNMKSRLKRNGIEFYPMLPIQPFKLKYQRPDLRNHRKL FT LVIDDAIAFVGSLNIIDPFYNTRGRKKMFWQDAMLRLEGPVISGISAVFVSDWYAETGQ FT LLRDYRIVKTSSGDSFTENRTQSNSVDRSCPSTNNVLCQVVPSGPGFEGENNLQLFLML FT LYASQKRVAITSPYFVPDEAMTLAIVSATKRGVSVELFLSENHDQKIVYHAQCSYYEQL FT LRSGVKIWLYRAPNFLHSKYVTVDDDVAVFGSSNFDMRSFNLNMEMSLLLYSKEFVAKL FT QAVEQENRANSSLLTLDEWMHRGKMDRLKDNLARLTSALQ" FT misc_feature order(65844..65912,65931..65999) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-27 and 34-56" FT misc_feature 66471..66552 FT /note="Phospholipase D. Active site motif Score = 27.9 FT E-value = 1.7e-05" FT misc_feature 67062..67143 FT /note="Phospholipase D. Active site motif Score = 28.7 FT E-value = 9.3e-06" FT CDS 67380..69902 FT /transl_table=11 FT /locus_tag="TW075" FT /product="putative Clp-family ATP-binding FT protease/regulator" FT /note="Similar to Bacillus subtilis negative regulator of FT genetic competence ClpC/MecB SWALL:CLPC_BACSU FT (SWALL:P37571) (810 aa) fasta scores: E(): 3e-152, 56.66% FT id in 810 aa, and to Streptomyces coelicolor putative FT Vlp-family ATP-binding protease SCO3373 or SCE94.24c FT SWALL:Q9S6T8 (EMBL:AL049628) (841 aa) fasta scores: E(): FT 7.6e-189, 65.87% id in 838 aa" FT /db_xref="GOA:Q83ID8" FT /db_xref="HSSP:1JBK" FT /db_xref="InterPro:IPR019489" FT /db_xref="UniProtKB/TrEMBL:Q83ID8" FT /protein_id="CAD66762.1" FT /translation="MGEDMFERFTDKARRVIVLAQEEARTLSHNYIGTEHVLLGLISEG FT DGIAAQALESLDITLERAREGVAELIGRGQNATSGHIPFTPRAKKVLELSLREALQLGH FT NYIGTEHILLGILHEGEGIAAQVLVNMGAELPAIQQRVMHLLEDGREQEPVSVGPSESG FT KISGSQILDQFGRHLTRAAKEGKLDPVIGREKEIERVMQVLSRRTKNNPILIGEPGVGK FT TAVVEALAQAIVNGDVPVNLRNKQVYSLDLGSLIAGSRYRGDFEERLKKVTKEIRSRGD FT IIVFIDEIHSLVGAGSAEGAIDAATILKPLLARGELQTIGATTLDEYRKNIEKDSALER FT RFQPVNVSEPSIPMCIQILKGLRDRYEAHHKVKITDEAIYAAVTLSSRYINDRFLPDKA FT IDLIDEAGARLRLSVLSNPSQLRAVEKKILAVVARKDKAVEKQDFDKVGELKRKEKALR FT AELRKIKRDYENGNIASAGTVDEGLIAEVLASATGVPVFRLTEDESVRLMMMERSLHQR FT VIGQDEAISSLSRAMRRTRAGLKDPNRPSGSFIFAGPTGVGKTELAKALAEFLFDNEDA FT LVSLDMSEYGERHTVSRLFGAPPGFVGFEEGGQLTEKIRRKPFSVVLFDEIEKAHPDVF FT NSLLQILEEGRLSDAQGRMVDFRNTIIVMTTNLGSRDIASGPVGFQSGDGSFLAYEAMK FT AKVNEELRRSLKPEFLNRIDEVIVFPPLNRDELLQILKIFIKKLDDRLRDRTMRLSVTD FT AALEQLVQIGYEPTMGARPLRRAVQREVEDRISEKILLGEIKPNQEIEMDFVNDNFTIV FT SRDMDYPLSPLVPSVTTGLVTPDLASHV" FT misc_feature 67437..67593 FT /note="Clp amino terminal domain Score = 69.5 E-value = FT 5e-18" FT misc_feature 67662..67818 FT /note="Clp amino terminal domain Score = 74.2 E-value = FT 1.9e-19" FT misc_feature 68010..68589 FT /note="ATPase family associated with various cellular FT activities (AAA) Score = 44.1 E-value = 2.3e-10" FT misc_feature 68025..68048 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 69021..69681 FT /note="ATPase family associated with various cellular FT activities (AAA) Score = 15.1 E-value = 5.8e-06" FT misc_feature 69036..69059 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 70637..72220 FT /transl_table=11 FT /gene="menD" FT /locus_tag="TW078" FT /product="putative menaquinone biosynthesis protein MenD" FT /EC_number="4.1.3.-" FT /note="Similar to Bacillus subtilis menaquinone FT biosynthesis protein MenD [includes: 2-succinyl-6-hydroxy- FT 2,4-cyclohexadiene-1-carboxylate synthase MenD FT SWALL:MEND_BACSU (SWALL:P23970) (580 aa) fasta scores: E(): FT 3.6e-17, 28.57% id in 525 aa, and to Mycobacterium leprae FT putative FT 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate FT synthase / 2-oxoglutarate decarboxylase MenD or ML2270 FT SWALL:Q9CBB0 (EMBL:AL583925) (556 aa) fasta scores: E(): FT 1.4e-25, 32.95% id in 531 aa" FT /db_xref="GOA:Q83ID7" FT /db_xref="InterPro:IPR012001" FT /db_xref="UniProtKB/TrEMBL:Q83ID7" FT /protein_id="CAD66763.1" FT /translation="MTCASGIAFCLLNLLAERGVRDIVVAPGARSQALALAAVALERAG FT LVRLTVRIDERVAAFTAFGMAKALDSPAVVITTSGSAVANLYPAVVEASHSFVPLIVIT FT ADRPRELHGKRSNQTMNQEKFFSHWVRFFCHIEQDVPGERVIDSALQAALGVSSLRGAG FT PGPVHINVAFDNPLSCAHAVQPGDNKGSALKHKKVLRSKRETLVLRKDDPPTVIIAGTG FT SGRRPADIACATGWPLVAEISSGSRFGPFLIKNYRNWLTENSLDIRRAIVFGHPTLSSE FT IPTFLTKRNIDTIVVAPFGREFYNPSGTARPVANVLVDEDSFSGIPLGAAKFASASAGC FT ISQDVISSDRPRGHRVTRQQLVSEIWNITKEDEILFFGSSQLIRVADSILPGKRVTVFA FT NRGLSGIDGNLSTAAGIAIATNRTTRVLVGDLTGVHDIGALLIPLMEAKYRLQIVIGND FT FGGGIFDTLEVHATPSDYKRVLYVPCRVDFRLVSHAFGWKYTFCPDPNSLRKALKSRIF FT PHLLEVHLAV" FT misc_feature 70640..71186 FT /note="Thiamine pyrophosphate enzyme, N-terminal TPP FT binding domain Score = -42.9 E-value = 5.4e-05" FT CDS 72230..72775 FT /transl_table=11 FT /locus_tag="TW079" FT /product="putative secreted protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NV7" FT /protein_id="CAD66764.1" FT /translation="MKRVYLRRRIMLSMLIVLPLIVAVFFATGSPGHERPALPQPTPIK FT VADDRCTEEQIAVFVTSDRESYTKNRLPAFRASVRNIGISPCRINVGTASQSYRIIRDG FT KLIWDSKICLVDPTNALVMLLPKQTLTSQTLTWHREIANISDCGKDFSVRPKATPGEYT FT VEFSIDGFSSSKYNFVLQ" FT misc_feature 72230..72367 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.820 between residues 46 and 47" FT misc_feature 72263..72316 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 12-29" FT CDS 72796..73707 FT /transl_table=11 FT /gene="menA" FT /locus_tag="TW080" FT /product="1,4-dihydroxy-2-naphthoate octaprenyltransferase" FT /EC_number="2.5.1.-" FT /note="Similar to Escherichia coli FT 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA or FT b3930 SWALL:MENA_ECOLI (SWALL:P32166) (308 aa) fasta FT scores: E(): 8.9e-17, 33.45% id in 275 aa, and to FT Mycobacterium tuberculosis probable FT 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA or FT Rv0534c or mt0558 or mtcy25d10.13C SWALL:MENA_MYCTU FT (SWALL:O06400) (292 aa) fasta scores: E(): 2.8e-24, 40.63% FT id in 251 aa" FT /db_xref="GOA:Q83ID6" FT /db_xref="InterPro:IPR004657" FT /db_xref="UniProtKB/TrEMBL:Q83ID6" FT /protein_id="CAD66765.1" FT /translation="MALEKRRRKKKRSLILPWLLASRPATLIVSLSAVSLGWGAALLTV FT TGRKASLLLVALAALTAVLLQIGANYINDYGDGIRGADSNRSHASRRLTASGANPFSVL FT TTGLSFLIAAAGSGLIAVILTQRWQLILVGVFSIAAAYLYTAGPFPYAYFGLGELSVFI FT FFGPVTVIGTVFLLSGIVTLSSFLVAVVAGSWSAAILLMNNLRDHESDMQSNKRTFSVL FT FGVLIARIVCIALIAVPYIVVAILLIELPFIGYVFLTLLLSAPIVIILATAVTSKEFAI FT AFRLGIICLIPFAIFFTWGLAS" FT misc_feature 72796..72942 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.999) with cleavage FT site probability 0.204 between residues 49 and 50" FT misc_feature order(72832..72900,72943..73011,73072..73140,73183..73251, FT 73270..73338,73351..73410,73468..73536,73546..73614, FT 73633..73701) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35, 50-72, 93-115, FT 130-152, 159-181, 186-205, 225-247, 251-273 and 280-302" FT misc_feature 72880..73696 FT /note="UbiA prenyltransferase family Score = 64.0 E-value = FT 2.3e-16" FT CDS 73945..77412 FT /transl_table=11 FT /gene="rpoB" FT /locus_tag="TW081" FT /product="DNA-directed RNA polymerase beta chain" FT /EC_number="2.7.7.6" FT /note="Previously sequenced as Tropheryma whipplei FT DNA-directed RNA polymerase beta chain RpoB FT SWALL:RPOB_TROWH (SWALL:Q93GF2) (1216 aa) fasta scores: FT E(): 0, 99.56% id in 1155 aa. Similar to Mycobacterium FT tuberculosis DNA-directed RNA polymerase beta chain RpoB or FT Rv0667 or mt0695 or mtci376.08C SWALL:RPOB_MYCTU FT (SWALL:P47766) (1178 aa) fasta scores: E(): 0, 65.56% id in FT 1150 aa" FT /db_xref="GOA:P59642" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR007641" FT /db_xref="UniProtKB/Swiss-Prot:P59642" FT /protein_id="CAD66766.1" FT /translation="MFGVGFLAFAKGKRVCAIGRSSLGKISDPLEVPNLLDLQLDSFDW FT LIGGPRWRAALDAYRKNPSGAPIAEKSGLDEVFDEISPIEDSAGNMQLNFSKPVLEAEE FT LSVRECRVRGRTYSAPLYVEAEFMNHDTGEIKTQTVFMGDFPLMTDKGTFVINGTERVV FT VSQLVRSPGVYFERTPEKNSEKDLFSGRIIPARGAWLEFEVDRHDQLGVRVDRKRRQPV FT IFFLRAIGMTDDEIRDAFGEFESISVQHEKNIGLSRDDALREIYRRVRPGEQASAEAGR FT ALLENFYFTSRRFDLARVGRYKVNRKLGVDVDPTRMVLTRSDIIATIRYLAALHLGFSE FT VAVLNSNKSVPISTDDIDHLGNRRIRPVGELVQNQLRAGLARMERVVRERMTTQDIEAI FT IPQTLINVMPIVAALKEFYGTSQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVE FT VRDVNPSHYGRMCPIETPEGPNIGLIGSLACYSRVNSFGFIETPYRRVVNGKVTDDIEY FT MTATQEDEHAIAQASTPLRPDNSFVDERVLVRRKGGEVEVVPADQVDYMDVSGRQMVSV FT ATSLIPFLEHNDANRALMGSNMQRQAVPLLVTESPLVGTGMERYVAIDAGDVLIAEDPG FT IVGDVSADVVTVKQDDGKHRDYHVGKFVRSNQGNCYNQRVVVRSGDRVEKGTVLADGPC FT TDKGELSLGRNLLVAFMPWEGYNFEDAIIISQNLVKDDTLSSIHIEEHEVSTRDTKLGS FT EEITRDLPNVSMDYIKDLDERGIIRIGAEVGPGDILVGKVTPKGETELSAEERLLRAIF FT NEKSMEVRDTSLKVPHGQQGTVIDVKLFDAVDGEDKLGAGINQRVVVYIAHKRKITEGD FT KLAGRHGNKGVISKILPVEDMPFMADGTPVDIILNPLGVPARMNFGQVLETHLGWISKQ FT GWKIEGDPDWAKDIRVREAQPDSRVSSPVFDGISEGEITGLFSSVFPNRDGERAVGSDG FT KAILYDGRTGEPFPEPISVGYMYVLKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGG FT QRFGEMEVWALEAYGAAHALQELLTIKSDDVVGRVKVYDAIVKGYPIPTPGVPESFKVI FT VKEMQSLCINIEVVSDGEDDVSADAETLQIEEGLDTSPKVEVGSLEEV" FT misc_feature 74044..75205 FT /note="RNA polymerase beta subunit Score = 78.2 E-value = FT 1.2e-20" FT misc_feature 74449..75001 FT /note="RNA polymerase Rpb2, domain 2 Score = 48.6 E-value = FT 1e-11" FT misc_feature 75208..75424 FT /note="RNA polymerase Rpb2, domain 3 Score = 145.8 E-value FT = 5.4e-41" FT misc_feature 75826..77077 FT /note="RNA polymerase Rpb2, domain 6 Score = 688.8 E-value FT = 1.9e-204" FT misc_feature 76552..76590 FT /note="PS01166 RNA polymerases beta chain signature." FT misc_feature 77083..77311 FT /note="RNA polymerase Rpb2, domain 7 Score = 170.3 E-value FT = 2.2e-48" FT CDS 77472..81299 FT /transl_table=11 FT /gene="rpoC" FT /locus_tag="TW082" FT /product="DNA-directed RNA polymerase beta' chain" FT /EC_number="2.7.7.6" FT /note="Similar to Aquifex pyrophilus DNA-directed RNA FT polymerase beta' chain RpoC SWALL:RPOC_AQUPY (SWALL:Q9X6Y2) FT (1576 aa) fasta scores: E(): 3.4e-124, 40.11% id in 1573 FT aa" FT /db_xref="GOA:Q820D9" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR012754" FT /db_xref="UniProtKB/Swiss-Prot:Q820D9" FT /protein_id="CAD66767.1" FT /translation="MATTEDIRRWSYGVVKKPETINYRTLKPEKDGLFGEQIFGPTRDW FT ECGCGKYKRSRYRGVVCERCGVEVTQSSVRRERMGHIELAAPVTHIWYFKGVPSRLGYL FT LDIAPKDLDKVIYFAAYMVVSLDEEGRKEDLQDLENELRLDIKQLRDACDASIASAVSE FT LERTITELQDAKTSASRINKVRSEAENKMANIRREYDDKIEHLERVWDSFKALKVGGLY FT AEDDVFRDVQDRYGDYFDACMGAEAIKRRLEDFDLQKTAQELGVQIVECRGQRKVRAIK FT RLRVVNSFITSKANPACMVLDVIPVIPPELRPMVQLDAGRFAASDLNDLYRRVINRNNR FT LKRLLDLGAPRIIVNNEKRMLQEAVDALFDNGRRGRPVSGTNNRTLKSLSDMLKGKSGR FT FRQNLLGKRVDYSGRSVIVVGPTLQLHQCGLPKLMALELFKPFIVKRLLDLALAPNIRS FT ARRMIERGDPAVWDMLDAVIKARPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCA FT AFNADFDGDQMAVHLPLSLEAQAEARVLMLASNNILNPSDGRPVTLPSHDMIIGLYHLT FT TVKPSAKGAGRAFSSVAEAIMAKDRGDLSISAPVKILFSNIVLDGKTLDSAVVETTLGR FT AIFNEALPDGHPYINELVDKQVISSIINNLAEVYSKVEVANTLDKIKSVGFHWATRSGV FT TVAISDVVSPPEKQEIISKYETQARGVQQDFEIGLLTDLERRQALVSIWSEATDRVAEA FT MRKCFPDDNTINTMVTSGARGNWLQVRNIAGMRGLVANPKGETIPRPIISSYREGLSVT FT EYFISTHGARKGLVDTALKTADSGYLTRRLVDVAQDVVVRERDCGFTRGVRMPVTFRGD FT DGELHKVENAEHSVYGRTLAEDVKTPDDNLIAKAGEDISGIMIDSFIAAGVESVEVRSV FT LTCRSKVGVCSACYGRSLATGARVDIGDAVGIVAAQSIGEPGTQLTMRTFHSGGSASAV FT DITQGLPRVQELFEARTPRAAAPIAEADGTVSIEDGDRARRLILKSDNNEEFSYTVLKR FT AQLRVKDGSRVSLGDQLVEGSLDPKEVLRVKGIRAVQEYLVNGVQQVYRSQGVPIHNKH FT IEVIVRQMLRKVTVVDHGDTSMLPGELIDQSRYQELNREAQAEGRKTASARQEVTGITK FT ASLATESWLSAASFQETTRVLTQAVISGRRDPLIGLKENVIIGNLIPAGTGLSVYRDVE FT PEPRPEAISRMYPTRRPEIENLLEGDSVDPEFDFSSLTQGLELPDDYPVQ" FT misc_feature 78687..79113 FT /note="RNA polymerase Rpb1, domain 2 Score = 282.9 E-value FT = 2.9e-82" FT CDS complement(81523..82884) FT /transl_table=11 FT /locus_tag="TW083" FT /product="putative hydrolase" FT /note="Similar to Synechocystis sp. serine esterase sll1284 FT SWALL:P73192 (EMBL:D90904) (204 aa) fasta scores: E(): FT 0.0001, 29.01% id in 193 aa" FT /db_xref="GOA:Q83ID5" FT /db_xref="InterPro:IPR003140" FT /db_xref="UniProtKB/TrEMBL:Q83ID5" FT /protein_id="CAD66768.1" FT /translation="MNNFDASAPIDECRVLGHVNENRFLLLAMHGYSGNNQVMYDTVKS FT FMPQEIQAGISIVSLRAPIDLSSVSEGPDEGFAWFLFDESGSYKNSYKTLSQSAKQILS FT WLDTKKPAGIGLLGFSQGGAMCMELLRAAPEKFDFAVNISGFVWGPPRRDDSVLAGGLE FT KRVRYGDSLVTERRRTEVFWGLGKEDTILPYKVWEATQAWLLSVTNPEIRIYPELAHKI FT CDEEVRDISSFLLRHLENRVGRITPAIRCRWKEQDLTGKNVVLLLHGYGSSESELIRWT FT GPSAAQVSLDEQTEQYLPENTTYISLQGPIPEAMGYAWFDRNATDVGDAVNSVVNWFCD FT LVQTFGKPARVGLLGFSQGGAVCIELLLRHPELFDLAVVLSGFAVGSTTSSAKKPVLWI FT RGDSDSVIDENRVLSTKYVLEKSSELTEECLSGLTHEITPEVIARASKYLRAHL" FT misc_feature complement(81528..82152) FT /note="Phospholipase/Carboxylesterase Score = 19.9 E-value FT = 6.7e-10" FT misc_feature complement(82173..82329) FT /note="Phospholipase/Carboxylesterase Score = 26.2 E-value FT = 2.4e-07" FT CDS 82958..83341 FT /transl_table=11 FT /gene="groS" FT /locus_tag="TW084" FT /product="10 kDa chaperonin" FT /note="Similar to Streptomyces coelicolor and Streptomyces FT lividans 10 kDa chaperonin GroS or SCO4761 or SC6G4.39 FT SWALL:CH10_STRCO (SWALL:P40172) (102 aa) fasta scores: E(): FT 3.9e-21, 68.42% id in 95 aa" FT /db_xref="GOA:Q83NV6" FT /db_xref="HSSP:1HX5" FT /db_xref="InterPro:IPR001476" FT /db_xref="UniProtKB/TrEMBL:Q83NV6" FT /protein_id="CAD66769.1" FT /translation="MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRP FT ADAEQVTASGLVIPDTAQERPQEGEVVAVGPGSLNDDGNRVPLDVSVGDRVIYARYGGT FT EVKLGDDEYTILASRDVLAVVHR" FT misc_feature 83051..83333 FT /note="Chaperonin 10 Kd subunit Score = 189.8 E-value = FT 3e-54" FT misc_feature 83057..83131 FT /note="PS00681 Chaperonins cpn10 signature." FT CDS 83392..84867 FT /transl_table=11 FT /gene="guaB1" FT /locus_tag="TW085" FT /product="inosine-5'-monophosphate dehydrogenase" FT /EC_number="1.1.1.205" FT /note="Similar to Bacillus subtilis FT inosine-5'-monophosphate dehydrogenase GuaB or GnaB FT SWALL:IMDH_BACSU (SWALL:P21879) (513 aa) fasta scores: E(): FT 2.1e-87, 50.92% id in 489 aa" FT /db_xref="GOA:Q83ID4" FT /db_xref="HSSP:1B3O" FT /db_xref="InterPro:IPR018529" FT /db_xref="UniProtKB/TrEMBL:Q83ID4" FT /protein_id="CAD66770.1" FT /translation="MHPHKLSGVGLTYDDVMLVPGRSDVLPSQVNFGSFLTRRIRLSAP FT LVSAAMDTVTESGMAVAMARLGGVGVIHRNMSIADQAEHVTRVKLSESGMITRPVSVSP FT DLTLEEVEQRCSRYKISGFPVVDEDNTLLGIVTSRDMWPYRHEHRASVRVSEVMTRSPL FT ITASPNISSEEARDLLYKHRLEKLPLVDEHGRLFGLITVKDFVNRQRYPFATKDKNGCL FT IVGAAIGFFGDAYDRALALAAAGVDFIVVDTANGYSDGALKMINRLKNDSTFADIDIIG FT GNVATGDGAKALIDSGADAVKVGIGPGSICTTRVIAGVGVPQITAIYECAQTSSVPIIA FT DGGLHYSGDIAKALVAGAKSVMLGGLLAGCDESPGELISRGGKQYKIYRGMGSAGAMQA FT RASYSRDRYFQHDLDSHPIAEGVEGQVPHTGSVSTVFYQLLGGLRQSMFYVGCRDINEL FT QDKGRFVRITSAGLKESHPHDIEMIVETPNYRT" FT misc_feature 83392..84856 FT /note="IMP dehydrogenase / GMP reductase Score = 647.7 FT E-value = 4.4e-192" FT misc_feature 83668..83827 FT /note="CBS domain Score = 55.5 E-value = 8.2e-14" FT misc_feature 83860..84019 FT /note="CBS domain Score = 45.7 E-value = 7.6e-11" FT misc_feature 84292..84330 FT /note="PS00487 IMP dehydrogenase / GMP reductase FT signature." FT CDS 84872..85993 FT /transl_table=11 FT /gene="guaB2" FT /locus_tag="TW086" FT /product="putative inosine-5'-monophosphate dehydrogenase" FT /note="Similar to Streptomyces coelicolor putative FT inosine-5'-monophosphate dehydrogenase SCO4771 or SCD63.03 FT SWALL:Q9L0I6 (EMBL:AL161755) (374 aa) fasta scores: E(): FT 7.1e-82, 58.64% id in 370 aa, and to Escherichia coli and FT Escherichia coli O157:H7 inosine-5'-monophosphate FT dehydrogenase GuaB or b2508 or z3772 or ecs3370 FT SWALL:IMDH_ECOLI (SWALL:P06981) (488 aa) fasta scores: E(): FT 7.5e-05, 32.94% id in 170 aa" FT /db_xref="GOA:Q83NV5" FT /db_xref="HSSP:1B3O" FT /db_xref="InterPro:IPR005992" FT /db_xref="UniProtKB/TrEMBL:Q83NV5" FT /protein_id="CAD66771.1" FT /translation="MEVGFSRNARRAFSLDEVAVVPSRRTRHSSEVSIEWKMDAFSFDT FT PIISSPADSVVSPSTIVELSEFGCLGILDLEGVWTRYENPEPVLREISALPEEKACLGL FT QKIYSEPIKRHLLERRLQELRDAGVIVAGCLSPQTTNALYKSVISAGVDIFVIRGGTVS FT AEHVSKSDNVLNLKRFIYELDVPVMVGGVATYTAALHMMRTGAAGVLVGFGGCAGSTNH FT ASLGIKVPMATAIADVAAARKDYLDESGGRYVQVIADGSMNTSGMAVNALALGADAVMM FT GTPLVRSTTSPGFGYHWGREAHHMTLPRGRRAYIGQTASLQEIIQGPGHSPDGTVNFAG FT AIRRAVALAGFQDLKNFQRVEMVVIQDQRRCCA" FT misc_feature 85421..85748 FT /note="IMP dehydrogenase / GMP reductase Score = 39.4 FT E-value = 1.7e-11" FT CDS 85986..86699 FT /transl_table=11 FT /locus_tag="TW087" FT /product="putative membrane protein" FT /note="Similar to Streptomyces coelicolor putative membrane FT protein SCO1829 or SCI8.14 SWALL:Q9RJ39 (EMBL:AL132644) FT (290 aa) fasta scores: E(): 0.37, 25.79% id in 252 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NV4" FT /protein_id="CAD66772.1" FT /translation="MPKAYFKLSSLLLLAPFLVVSFCFVYLGFWQLSRSYSPQDDPGTG FT IVTDFSVHTHILHGQRIALEGQLIPEDTLIVSDRYEKGESTWWLVARYNTPNGALPAVL FT GYGDRNAVATACSHLKQTKVVASQKISGRFYYDEPPDSLKLPESGTLNRMSSAAMINMW FT RKFSDPRVFSGFVVLDDPPGLGLGRVSILPGQPARINWLNIFYAVEWFLFAGFCLYVWF FT YLVRTPEIESCAKRD" FT misc_feature 85986..86096 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.976) with cleavage FT site probability 0.587 between residues 37 and 38" FT misc_feature order(86013..86072,86586..86654) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 10-29 and 201-223" FT CDS 86765..87202 FT /transl_table=11 FT /locus_tag="TW088" FT /product="putative membrane protein" FT /note="Similar to Corynebacterium glutamicum hypothetical FT membrane protein Cgl2499 SWALL:BAB99892 (EMBL:AP005281) FT (118 aa) fasta scores: E(): 0.0015, 31.53% id in 130 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NV3" FT /protein_id="CAD66773.1" FT /translation="MPKGSSEQEPVRQPVCPGDNSVLSAFRMYRAASSITGVLLILVCV FT EMFLKYILGVQVFALTGGALVELYHVDAPEPSGLNLSVMTLIFHGWFYVFYLWSDLYLW FT SKVRFGFALFIVIALGGVVPLMSFVVERYVYKKLSKRFVST" FT misc_feature order(86861..86929,86990..87058,87086..87154) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 33-55, 76-98 and 108-130" FT CDS 87199..88710 FT /transl_table=11 FT /gene="guaA" FT /locus_tag="TW089" FT /product="GMP synthase [glutamine-hydrolyzing]" FT /EC_number="6.3.5.2" FT /note="Similar to Bacillus subtilis GMP synthase FT [glutamine-hydrolyzing] GuaA SWALL:GUAA_BACSU FT (SWALL:P29727) (513 aa) fasta scores: E(): 2.2e-94, 50.49% FT id in 509 aa" FT /db_xref="GOA:Q83ID3" FT /db_xref="HSSP:1GPM" FT /db_xref="InterPro:IPR018318" FT /db_xref="UniProtKB/Swiss-Prot:Q83ID3" FT /protein_id="CAD66774.1" FT /translation="MRPVLVVDFGSQYSQLVVRAIRECGYYAEFASPSISAAECLALSP FT IAIFLSGGPASAYKDNAPKLDEEIFNCGIPIFGICYGFQLLAQAFGGSVKKANAPEYGP FT ADITIVNKAFFSGQPDRQTVWMSHGDSVIRAPKNFCILSTSQDAVLSFCNRDRTIAGVQ FT WHPEVKHSRFGKHTIKAFLSSFAAPNWDPEQTICGTVDSIRKTVGCKRVLCALSGGVDS FT VVAATLTHRAIGDRLRCVFVDHGLLRLNEREQVEEYCSSLGLNVSTYDASDCFLSALSG FT IRDSEQKRKVIGREFIACFSKLQERFDIKPHFLLQGTLYPDLVESGATPGGATIKSHHN FT VGGLSDNLGFELLEPLKYLFKDEVRKIGLQLGIPKHIVHRQPFPGPGLAIRIIGEVTNK FT KLSILRAADAIVRHELRDWTDIWQCPVILLSDVQSVGVRGDSRSCGFPIVIRPVSSDDA FT MTADWYRLPYDVLARISGRITNEIPEIVRVVLDITPKPPATIEWE" FT misc_feature 87211..87748 FT /note="Glutamine amidotransferase class-I Score = 137.2 FT E-value = 2.1e-38" FT misc_feature 87421..87456 FT /note="PS00442 Glutamine amidotransferases class-I active FT site." FT misc_feature 88351..88702 FT /note="GMP synthase C terminal domain Score = 195.4 E-value FT = 6.1e-56" FT CDS 88815..91046 FT /transl_table=11 FT /locus_tag="TW090" FT /product="ATP-dependent DNA helicase" FT /note="Similar to Bacillus subtilis ATP-dependent DNA FT helicase PcrA SWALL:PCRA_BACSU (SWALL:O34580) (739 aa) FT fasta scores: E(): 1.1e-72, 41.42% id in 758 aa" FT /db_xref="GOA:Q83ID2" FT /db_xref="HSSP:1PJR" FT /db_xref="InterPro:IPR014017" FT /db_xref="UniProtKB/TrEMBL:Q83ID2" FT /protein_id="CAD66775.1" FT /translation="MTIPADLLKGLNPQQVEGVCYRGPTLLISAGAGSGKTKVLTHRIA FT GFLATGEASCDQILAITFTNKAASEMRHRTGDLVGLSVRDMQISTFHSVCVRILRECVG FT HLGKAKNFTIYDAADQRAIIKQICQSTDTFGLTASMVASQIGLLKNQMHTPDTYSRCLA FT SNSTNGNSVTSITLQREQFILHVFRRYQEILKEANAFDFDDLISETVFLLQKSPEISAM FT YRNRWKYLLVDEYQDTNHAQYRLILELTKGDKSDMSLTAVGDSDQSIYAFRGADIANIV FT NFENDFPDCHTILLEQNYRSCQNILLAANALISNNQNRKDKNLWSELGAGEKVVAYCAS FT SAEEEGRFVADRVRHLVDQGESLSDIAVFYRSNTQSRAIEESLIRQSIPYRVVGGTKFY FT ERAEIKDILAYLTVIVNPDDTLALRRILNVPKRGVGTVSENRLVEFASARGITLMQALS FT RIDEINIQPSAKSALRDLFYLLNRFAGSSMPANELLDDLLKATDLLSRFNNTDDPQNEA FT RKINIGDFVDSVEDFAKENPGGTLSDFMTNIALMTSYDQSDDAPGQITLMTLHMAKGLE FT FDFVFLTGLEEGILPHEMSLKEKNGIEEERRLAYVGMTRAKKVLHLSFSSYRKRYTDGV FT RLPSRFWDEIPQHLLRWHSRFTHKRFTGPLYGFTARPAGESRQSVHVLKDRYPRESFSI FT SDSVKHSVFGVGTVVDVLGLGPKQIIVVEFADKRRSLLASIAPIVKCKQ" FT misc_feature 88845..90321 FT /note="UvrD/REP helicase Score = 607.9 E-value = 4.2e-180" FT misc_feature 88902..88925 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 91313..92797 FT /transl_table=11 FT /locus_tag="TW092" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="GOA:Q83NV2" FT /db_xref="InterPro:IPR009056" FT /db_xref="UniProtKB/TrEMBL:Q83NV2" FT /protein_id="CAD66776.1" FT /translation="MKVLPLLFVTALDACFAVVTPILIPLVVLLVSWIFSDNLYGPFSY FT RLEGALAIWGAGFGVPVRVLRPLEFSVSIIPLSMTLVTMLISLRLARRCVLFGRRILLF FT VIASIAYVITAMVILSFVHWELVTLDPVKVIFFGLFLYISFALLASEILINRNHSRIVT FT PIIRLHAPKWLRELAGLSMRCAIMLLLLQLSLASMVFAGLQFLHTFDTVQIYNSMHAGI FT VGLISITLLQLAFLPNFLIWIISWQVGAGFYIGGLHFGGFSIDHGDYSLPLVPVFASLP FT AQNFPLMGNIILTTVCVIPVGIWLMKNRSISFSFGWKLVIGFSGVVLATLSLVFLSYLS FT GGSISPRQSVGIDLLLLFLLSFADIFCGVLVGVVIGIIFKPYTAYERIKTPRVWEYLGH FT LPSRASSLLPIFGRPNANKAPVNKVSVSKTTELNTGNTPETSGRSVFTAVYFWRTICRV FT CHVKRLWGKQSKVDPAIKGKSRNKPGLGVPRMKDLE" FT misc_feature order(91349..91417,91514..91582,91616..91684,91712..91771, FT 91868..91936,91964..92032,92036..92104,92162..92230, FT 92267..92335,92378..92446) FT /note="10 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35, 68-90, 102-124, FT 134-153, 186-208, 218-240, 242-264, 284-306, 319-341 and FT 356-378" FT CDS 92799..93437 FT /transl_table=11 FT /gene="purN" FT /locus_tag="TW093" FT /product="phosphoribosylglycinamide formyltransferase" FT /EC_number="2.1.2.2" FT /note="Similar to Mycobacterium paratuberculosis PurN FT SWALL:Q9RAJ6 (EMBL:AF191543) (209 aa) fasta scores: E(): FT 1.5e-21, 42.39% id in 184 aa and to Escherichia coli FT phosphoribosylglycinamide formyltransferase PurN or b2500 FT SWALL:PUR3_ECOLI (SWALL:P08179) (212 aa) fasta scores: E(): FT 2.1e-17, 36.2% id in 174 aa" FT /db_xref="GOA:Q83ID1" FT /db_xref="HSSP:1MEO" FT /db_xref="InterPro:IPR004607" FT /db_xref="UniProtKB/TrEMBL:Q83ID1" FT /protein_id="CAD66777.1" FT /translation="MKTAMRLIVMVSGIGSGLLRLIRACEQKELKAEIVAVGSDRHAPA FT LSHASDYGIPFFVSPFKEYSNRDAWGANLLNTVLAYKPDLVVLSGFMRILPSCVVDALS FT PNLINTHPSYLPEFPGMNAVEDALRAGVKTTGASVIRVDNGIDTGPVISQMRVKVYSSD FT TCQTLHSRIKKVEHLLLCRAIKNIYTEQFILKNLLHNSVRRPSGKTGDR" FT misc_feature 92811..93348 FT /note="Formyl transferase Score = 147.5 E-value = 1.7e-41" FT CDS 93477..95105 FT /transl_table=11 FT /gene="purH" FT /locus_tag="TW094" FT /product="bifunctional purine biosynthesis protein PurH" FT /EC_number="2.1.2.3" FT /note="Similar to Mycobacterium paratuberculosis PurH FT SWALL:Q9RAJ5 (EMBL:AF191543) (527 aa) fasta scores: E(): FT 8.2e-59, 50.46% id in 543 aa, and to Escherichia coli FT bifunctional purine biosynthesis protein PurH [includes: FT phosphoribosylaminoimidazolecarboxamide formyltransferase FT purh or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) FT fasta scores: E(): 2.6e-27, 39.48% id in 547 aa" FT /db_xref="GOA:Q83ID0" FT /db_xref="HSSP:1G8M" FT /db_xref="InterPro:IPR011607" FT /db_xref="UniProtKB/TrEMBL:Q83ID0" FT /protein_id="CAD66778.1" FT /translation="MTTNIRIKRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIR FT GVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQLQQLGVDAFDLVV FT VNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHTRVVVIVDPSDYIHVINSLE FT RGAPSRLRHQLAIKAYSHTSEYDLHISRWLSERFYKHTLYSSSDSVGDVCDNNLDSNDH FT FVELRGKKLGDLRYGENSHQKASLYLSCKESVPQLGLASAALLGGKQMSYNNYLDADVA FT SRIVNSFDLPTVSFVKHGNPCGIASNIEVAIACRNAHECDPTSAFGGVVAVNREVTLDV FT ATHLLPIFIEVVVAPGYDPQALQLLLKKKNLRVVELPECASYPQDQLRQISGGFLVQDA FT DKFDHHDTFSSWTQVSGPRIFMDAGADNETLMDLEFAWKSCAFVKSNAILLAKNMASVG FT IGMGQVNRLDACYLAVNRAGSRSLGAVAASDAFFPFSDGLDVLINSGVKAIVQPGGSVR FT DNAVIAAAQQAGVTMFFTGKRHFAH" FT misc_feature 93504..93876 FT /note="MGS-like domain Score = 106.3 E-value = 4.1e-29" FT misc_feature 93891..94905 FT /note="AICARFT/IMPCHase bienzyme Score = 360.0 E-value = FT 1.8e-105" FT CDS complement(95180..95521) FT /transl_table=11 FT /locus_tag="TW095" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NV1" FT /protein_id="CAD66779.1" FT /translation="MKSMNKKLAVFLLARDLSFVLSATILEVWCLSSVTWPVNAIFGVV FT LPIVLGLGWACILSTSPAISASIYLRSIVYLVVSLLAALSLIDFRSIGLAVAHLVLASF FT IGFVLVLLD" FT misc_feature complement(order(95189..95248,95261..95329,95348..95416, FT 95429..95497)) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 9-31, 36-58, 65-87 and FT 92-111" FT misc_feature complement(95393..95521) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.620) with cleavage FT site probability 0.196 between residues 43 and 44" FT CDS 95602..96681 FT /transl_table=11 FT /locus_tag="TW096" FT /product="putative integral membrane protein" FT /note="Weakly similar to Streptomyces coelicolor putative FT integral membrane transport protein SCO0079 or SCJ11.08c FT SWALL:Q9RI96 (EMBL:AL109949) (407 aa) fasta scores: E(): FT 2.3e-19, 26.37% id in 364 aa" FT /db_xref="InterPro:IPR011701" FT /db_xref="UniProtKB/TrEMBL:Q83NV0" FT /protein_id="CAD66780.1" FT /translation="MIPASAIKYMAEDLNVSLGKIGFLITLFSFAVILTAPILTIITRG FT ISRRSLMTTVIIFLGLFHASAALFTGYEMVAVVRFLTGAVHGMFWTLVGSIVGQLYAPR FT SLARAMSIVLGGGTVSYVIGLPLSNFFAFQFGWKSVVIVLGIMFVLLGLLFNFTLKVPL FT HSARMGPAKNRNVFKSKWMPICILSASVLLGQFIFSSYVPAFLSKRYSPEFVSILLFVY FT GFCGCIGNVLAGVFKPTRRRFMVIIATSLICILLFSFMDNAIGLAAYAIWGAMFGAVPV FT LLTVFLLSNTSDNNRDIANAYYTMSFNIGIGSGALFGGLFLDGFGFYVLPLASCAALLL FT SFLLSLRTVSGRHNPADTG" FT misc_feature order(95659..95727,95764..95817,95827..95895,95932..96000, FT 96010..96078,96139..96198,96241..96309,96328..96381, FT 96391..96459,96493..96561,96571..96639) FT /note="11 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 20-42, 55-72, 76-98, 111-133, FT 137-159, 180-199, 214-236, 243-260, 264-286, 298-320 and FT 324-346" FT CDS complement(96582..97733) FT /transl_table=11 FT /gene="truB" FT /locus_tag="TW097" FT /product="tRNA pseudouridine synthase B" FT /EC_number="4.2.1.70" FT /note="Similar to Escherichia coli and Escherichia coli FT O157:H7 tRNA pseudouridine synthase B TruB or p35 or b3166 FT or z4527 or ecs4047 SWALL:TRUB_ECOLI (SWALL:P09171) (314 FT aa) fasta scores: E(): 2.2e-23, 35.24% id in 227 aa" FT /db_xref="GOA:Q820Z5" FT /db_xref="HSSP:1K8W" FT /db_xref="InterPro:IPR014780" FT /db_xref="UniProtKB/Swiss-Prot:Q820Z5" FT /protein_id="CAD66781.1" FT /translation="MLGKVERSEMYILFAMTQVLLVDKISGITSHTAVAKIRHLTGVKK FT IGHCGTLDPAACGLLIMGCGTATRLIRYMSNLDKRYIATITLGTQTTTDDSEGEIIYSA FT PKPSLDKITLESIGRAAEKLSGTIKQIPSAYSAIKVSGNRAYNLARQGIIPKLNAREVR FT VHWKFLGDFENNQVHVQITCSSGTYVRALARDMGKFLGVGGHLSYLKRLSIGPFHLHEI FT YREINKKEATMSERTPSGNTQGLTDNMAISDNMAISESDKHDCTEPGINCTELGIKDTC FT TALREVHYTQGDTLSFTRLTALQALSRIYKPIEVSQKQADDLSCGRYISLGIDSNGPVC FT AVCKENLIAVIQPVSAGLWRPETVLSDNRKLNSNAAQDASGST" FT misc_feature complement(97169..97631) FT /note="TruB family pseudouridylate synthase (N terminal FT domain) Score = 155.3 E-value = 7.4e-44" FT CDS 97781..98905 FT /transl_table=11 FT /locus_tag="TW098" FT /product="putative metalloprotease" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT zinc metalloprotease Rv2869c or mt2937 or mtv003.15C FT SWALL:YS69_MYCTU (SWALL:O33351) (404 aa) fasta scores: E(): FT 8.7e-11, 34.51% id in 423 aa" FT /db_xref="GOA:Q83IC9" FT /db_xref="InterPro:IPR006025" FT /db_xref="UniProtKB/TrEMBL:Q83IC9" FT /protein_id="CAD66782.1" FT /translation="MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPS FT LFSFKKRETSYSFNLLPLGGYVQLEGMLPPSENPRRWFKKLMKFAESDSPRAFWRLPAW FT KKIIVMFSGPFVNLILATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDEIIA FT INDTAISSPGQIRGLIQDKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFD FT ALSSMVKDTVGVAKSLIALPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISL FT YDKLRSMIWIFASLNLALFVFNMIPLLPFDGGYIAAAVFEGARSRVLLAFRKNDYAPVN FT ISYLLPVTLLVTAAIIVMSIMLAWIDIVNPLRLG" FT misc_feature order(97784..97852,98099..98167,98642..98710,98807..98875) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 2-24, 107-129, 288-310 and FT 343-365" FT misc_feature 97802..98876 FT /note="Peptidase family M50 Score = 122.5 E-value = FT 5.6e-34" FT misc_feature 97829..97858 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature." FT misc_feature 98096..98354 FT /note="PDZ domain (Also known as DHR or GLGF) Score = 11.3 FT E-value = 0.0056" FT CDS complement(98907..100013) FT /transl_table=11 FT /gene="dxr" FT /locus_tag="TW099" FT /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase" FT /EC_number="1.1.1.267" FT /note="Similar to Pseudomonas aeruginosa 1-deoxy-D-xylulose FT 5-phosphate reductoisomerase Dxr or pa3650 SWALL:DXR_PSEAE FT (SWALL:Q9KGU6) (396 aa) fasta scores: E(): 6.2e-42, 40.92% FT id in 391 aa" FT /db_xref="GOA:Q83IC8" FT /db_xref="HSSP:1K5H" FT /db_xref="InterPro:IPR013512" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC8" FT /protein_id="CAD66783.1" FT /translation="MQRVIIVGSTGSIGTQAIDFILKNRDSFLVVGLAASTQTSLLREQ FT AQVFGTKNTAQGASEAAELIEATEADVVLNAITGAAGLLSTYATLKTGKRLALANKESL FT IMGGKYFLDMTSFKGQITPVDSEHSAIAQAMKSGKFSEVNKLILTASGGPFYDRESLEG FT ITLKDALDHPTWNMGPMISINSATMFNKGLEIIEAHLLFGIPYSQIDVVIHPQSIVHSM FT VEYKDGSVIAQASVADMTLPIGYALSWPNRALNAVRPLEWGARQRWDFLPPTENSMRSI FT NLARRAGEAGGVYPAVLNASNECAVEAFMAGKISFARIIHVTETVFNLYTKQHTNRESA FT KNPIEVILEEDARTRELAKTVIENMSAD" FT misc_feature complement(98942..100004) FT /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase FT Score = 517.2 E-value = 8.4e-153" FT CDS 100065..100817 FT /transl_table=11 FT /locus_tag="TW100" FT /product="conserved hypothetical protein" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein SCO3845 or SCH69.15 SWALL:Q9XA19 (EMBL:AL079308) FT (515 aa) fasta scores: E(): 5.4e-22, 35.98% id in 239 aa, FT and to Rhizobium loti probable phosphoprotein phosphatase FT mlr2361 SWALL:Q98IK3 (EMBL:AP002999) (280 aa) fasta scores: FT E(): 1.4e-20, 36.08% id in 230 aa" FT /db_xref="GOA:Q83IC7" FT /db_xref="InterPro:IPR014045" FT /db_xref="UniProtKB/TrEMBL:Q83IC7" FT /protein_id="CAD66784.1" FT /translation="MSNRSTGSDDYIVSGKFSISWASLSHVGHHRESNEDSYSAKPPLW FT VVADGMGGHACGDIASGVVTSFLSAISSDFVSPQDITGALRQALASLAKKIGSTTAGTT FT LSGIGLSKVDNQPAWLVLNLGDSRVYCIESDKIRLLTEDHSIVHEMIKSGQITPEEAAI FT HPYNNIITRAVSFNSEPIPDFSFLPLRSGVRFIICSDGLTKELNDAQIETHATRGSPRE FT AAESLLYAALSAGGRDNITIILLDVHDK" FT misc_feature 100122..100782 FT /note="Protein phosphatase 2C Score = -16.8 E-value = FT 2.9e-06" FT CDS complement(100840..102411) FT /transl_table=11 FT /locus_tag="TW101" FT /product="conserved hypothetical protein (putative FT ATP-binding)" FT /note="Weakly similar to Methanosarcina acetivorans FT hypothetical protein Ma1866 SWALL:Q8TPP0 (EMBL:AE010868) FT (613 aa) fasta scores: E(): 0.0012, 22.1% id in 579 aa" FT /db_xref="UniProtKB/TrEMBL:Q820Z4" FT /protein_id="CAD66785.1" FT /translation="MQLKQVTITNYTPISDITLEVRRHLVLVGANDSGKTSILTCLDLL FT LSATTPMLYSHFQAWHFRDATKPIIISVDINNLDDKIQIAFGINNNRISEIKLTLSAFL FT DESQMLTIKREVLYNNTTKPVADSQLTGIGWELFDAGEVPCTASQYKTVLSGVMESTNL FT RQHGLSSLTQSFREQIEASPFLENLRERLAEKLIKTMPGNLNKDAVHLVPKDDIGTQVL FT GNIRVQVKRQNKSPHMIDCLDGMRSLYAVAIYDVLSRDASVVGIDEPETHLHPTIQRSL FT ARVLQEESNQKIIATHSADIVGAFSPEHVAVVQPNGQVVQPARGFLGEDERIIARWWVH FT GRLEPLTARRIVAVEGISDRIILESAAEVTGRNLDRLGIALIEANGSGDMWPIYKLFGP FT KGFRIPISLLIDSDAVQHTSVRLGIPKNEFTQNSIYVSKRDLEDEYTRAIGANTLWNAL FT RESKLFAHSELRGGGKTEQAVAAFCRKNSSNKVRAALVVSSLLNEQLAIAIESVNSLLN FT AIELPR" FT misc_feature complement(102304..102327) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 102673..102936 FT /transl_table=11 FT /locus_tag="TW103" FT /product="putative membrane protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NU9" FT /protein_id="CAD66786.1" FT /translation="MAACLFLAVLLTLRPILHPGFLLVPSDTIFGGLWLLTFVVGLIGV FT IYFMHMLIFTPLCDKVDHMEYTANFGVLDLATSHVKYQCGRR" FT misc_feature order(102685..102738,102766..102834) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-22 and 32-54" FT CDS 102921..103964 FT /transl_table=11 FT /locus_tag="TW104" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NU8" FT /protein_id="CAD66787.1" FT /translation="MWEKIADLRRSLTLSGVFFVYFTRKVFSYRLGLSSRMFILGICVL FT LYGTVLIYRLSLLAPVFYDFVTLIGAAESIINLFMAFLFAKILFLRSGGLMNFTMQLPL FT KNKERTMALTICEILIVFMGFTILYSPEAIVSTWKTGQPAYLLVNGLMPGFIAYILCSL FT IYNLSVRIFILFNLSRLSHIGGIIVTIFAFLGLLIFVGQSVQSLLPAPGQSIKQAYDHL FT QTDVFLIFNVFFWLFQHYGLLTSILAFLISLIILFPALIISIPSKYPDVHRFIKFPVPF FT INSTLWPFIAVFIRRIEWWVAVVVSILSIPLGGFVLILLNLHLLALFSAGIYMFSMSRA FT IRTATWI" FT misc_feature order(103011..103079,103122..103190,103251..103310, FT 103353..103421,103458..103526,103644..103712, FT 103749..103817,103860..103928) FT /note="8 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 31-53, 68-90, 111-130, FT 145-167, 180-202, 242-264, 277-299 and 314-336" FT CDS 103993..104355 FT /transl_table=11 FT /locus_tag="TW105" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NU7" FT /protein_id="CAD66788.1" FT /translation="MFAAQALCICPFLMLVQLALYIASFASGTIVPHDPINLSVILMFG FT VILPTFIGILFVHNEDNPVQAFAGYFVVSIIAMVTYLAISVTGQIFLLILFTEAIVAIP FT LTILAVQAVRKSERYA" FT misc_feature order(104095..104163,104182..104250,104260..104328) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 22-44, 51-73 and 77-99" FT CDS 104352..105071 FT /transl_table=11 FT /locus_tag="TW106" FT /product="putative ABC transport ATP-binding subunit" FT /note="Similar to Myxococcus xanthus PilH SWALL:O30385 FT (EMBL:AF003632) (326 aa) fasta scores: E(): 1.1e-12, 33.49% FT id in 206 aa, and to Streptomyces coelicolor putative ABC FT transporter ATP-binding protein SCO3633 or SCH10.11 FT SWALL:Q9X8Q0 (EMBL:AL049754) (311 aa) fasta scores: E(): FT 2.3e-11, 29.61% id in 233 aa" FT /db_xref="GOA:Q83IC6" FT /db_xref="InterPro:IPR003439" FT /db_xref="UniProtKB/TrEMBL:Q83IC6" FT /protein_id="CAD66789.1" FT /translation="MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKST FT FIKLVFDLLELQKGQIQILGNNHRLTTARLASIYLPSDDDLPEFLTGDEYLRTLFRLYK FT RPFDKNSVLREFDRFGMRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETINGID FT LDAVYECRKSITELKSRGHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLE FT DRVAEILGVDLHDRGAL" FT misc_feature 104439..104970 FT /note="ABC transporter Score = 87.8 E-value = 1.5e-23" FT misc_feature 104460..104483 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 104745..104789 FT /note="PS00211 ABC transporters family signature." FT CDS 105068..105424 FT /transl_table=11 FT /locus_tag="TW107" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NU6" FT /protein_id="CAD66790.1" FT /translation="MTQAFSRRSPFRKIKLVTAILSSSFALSMITVFVSFMYLVAITDP FT SSGVEQYHSLIFNTIYIRTEPSSKGVHIDISVGLLAVILPFLFFTIIISLCVFFYKKFI FT KNKKTTKSKKLPLK" FT misc_feature 105068..105211 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.999) with cleavage FT site probability 0.305 between residues 48 and 49" FT misc_feature order(105125..105193,105296..105364) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 20-42 and 77-99" FT repeat_region complement(105691..107456) FT /note="Non-coding degenerately repetitive sequence related FT to non-coding repeats at complement(108625..110025), FT complement(110760..111635), complement(113459..115135) and FT coding repeats at 117585..118355" FT tRNA complement(106618..106694) FT /note="tRNA Pro anticodon GGG, Cove score 78.34" FT CDS complement(107600..108649) FT /transl_table=11 FT /locus_tag="TW108" FT /product="putative DNA recombinase" FT /note="Similar to Corynebacterium glutamicum integrase FT Cgl1419 SWALL:BAB98812 (EMBL:AP005278) (304 aa) fasta FT scores: E(): 6.6e-16, 38.73% id in 333 aa, and to FT Pseudomonas aeruginosa integrase Inti1 SWALL:Q9AIL0 FT (EMBL:AF263519) (337 aa) fasta scores: E(): 4.4e-12, 28.75% FT id in 306 aa" FT /db_xref="GOA:Q83NU5" FT /db_xref="HSSP:1A0P" FT /db_xref="InterPro:IPR013762" FT /db_xref="UniProtKB/TrEMBL:Q83NU5" FT /protein_id="CAD66791.1" FT /translation="MSKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRN FT SLGIYLSWLGEQGTQRLSEVNSNAIERFLEYRQRHTRKSTLANTVAALRTFHRHLVLEG FT RQALNPTEKLQQPKVPKALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYGTGA FT RISEAVSLNVNAFAESDQNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSH FT VYRNITDASTLKYRPTSSTIGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKL FT GEAAEIGRYISPHSLRHSFATHMLQAGADIRTVQELLGHSSINTTSVYTKVTIDSLREV FT YTTSHPRAL" FT misc_feature complement(107635..108271) FT /note="Phage integrase family Score = 163.2 E-value = FT 3e-46" FT misc_feature complement(108337..108592) FT /note="Phage integrase, N-terminal SAM-like domain Score = FT 23.4 E-value = 0.00024" FT repeat_region complement(108625..110025) FT /note="Non-coding degenerately repetitive sequence related FT to non-coding repeats at complement(105691..107456), FT complement(110760..111635), complement(113459..115135) and FT coding repeats at 117585..118355" FT CDS complement(110016..110624) FT /transl_table=11 FT /locus_tag="TW109" FT /product="putative NUDIX hydrolase" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein sco1775 sco1775 or sci51.15C SWALL:Q9S225 FT (EMBL:AL109848) (211 aa) fasta scores: E(): 6e-27, 46.74% FT id in 169 aa, and to Bacillus subtilis adp-ribose FT pyrophosphatase nudF SWALL:ADPP_BACSU (SWALL:P54570) (185 FT aa) fasta scores: E(): 1.1e-13, 33.15% id in 184 aa" FT /db_xref="GOA:Q83IC5" FT /db_xref="HSSP:1MQE" FT /db_xref="InterPro:IPR000086" FT /db_xref="UniProtKB/TrEMBL:Q83IC5" FT /protein_id="CAD66792.1" FT /translation="MHYRVLESTLLHKGAVWDVVQEKLDYRGETISREFVSHPGAVGVL FT ALNDKNEALLIRQYRHPIRTREWEIPAGMLDLSGESPLDAAKRELSEEVDMCAQTWHTL FT IDFTLTPGGSNEVMRVYLARELRASQAKFNRKSEEADMEIAWIPMEDLLFSVLTRRVQN FT PVLMLAALAAHEGLQVQWKYLRDADEPWPVYERLKGLIS" FT misc_feature complement(110114..110513) FT /note="NUDIX domain Score = 83.9 E-value = 2.3e-22" FT repeat_region complement(110760..111635) FT /note="Non-coding degenerately repetitive sequence related FT to non-coding repeats at complement(108625..110025), FT complement(105691..107456), complement(113459..115135) and FT coding repeats at 117585..118355" FT repeat_region 111536..111619 FT /note="(taaccaaaataaacagttggg)4" FT CDS complement(111707..113344) FT /transl_table=11 FT /gene="pyrG" FT /locus_tag="TW110" FT /product="CTP synthetase" FT /EC_number="6.3.4.2" FT /note="Similar to Chlamydia trachomatis CTP synthetase PyrG FT or Ct183 SWALL:PYRG_CHLTR (SWALL:Q59321) (539 aa) fasta FT scores: E(): 4.8e-90, 48.3% id in 532 aa, and to FT Streptomyces coelicolor putative CTP synthetase PyrG or FT SCO1776 or SCI51.16c SWALL:Q9S224 (EMBL:AL109848) (549 aa) FT fasta scores: E(): 1.2e-104, 58.92% id in 538 aa" FT /db_xref="GOA:Q83IC4" FT /db_xref="InterPro:IPR000991" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC4" FT /protein_id="CAD66793.1" FT /translation="MNGIKHIFITGGVVSSIGKGLTAASLGSLLTMRGLKVFIKKLDPY FT LNVDPGTMNPLQHGEVFITEDGAETDLDVGHYERFLDVDLDRTANVTTGQVYSKVITLE FT RTGRYLGETVQVIPHITDEIKRRIRLAPDDIDVIITEIGGTVGDIESQPFIEAARQIRR FT EVGRENCCFIHVSLVPFLESAGEQKTKPTQHSVAILRAAGIQPDALVLRSDKPISSANQ FT KKIALMCDVSAVVNAVTVPNIYEIPCVLNQHGLDKFVIKHLDLEAGEIDWSYWDDVLDA FT IENNRSEIEIAIIGKYTGLPDAYISVIEALRAGGFESKTKVNIKWVDSDDENLEDQLEN FT INGACIPGGFGIRGIEGLIKAIRICREREIPTLGICLGMQCMVIEYARHVVGMHGASST FT EFTDDTQWPVVTTMLEQRDILIDDQFGGTMRLGSYRAVLSVGSLAASLYGTTDIHERHR FT HRYEVNNGYAQRLVERGLIVSGRNTEQDLIEFIELDRKDHPFYIGTQAHPECKSRPKRP FT HPLFKGLVAAALARKEIAEFNSGKTVLQ" FT misc_feature complement(111719..111742) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(111766..112450) FT /note="Glutamine amidotransferase class-I Score = 193.3 FT E-value = 2.7e-55" FT misc_feature complement(112199..112234) FT /note="PS00442 Glutamine amidotransferases class-I active FT site." FT misc_feature complement(113258..113326) FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29" FT repeat_region complement(113459..115135) FT /note="Non-coding degenerately repetitive sequence related FT to non-coding repeats at complement(108625..110025), FT complement(110760..111635), complement(105691..107456) and FT coding repeats at 117585..118355" FT repeat_region 115120..115176 FT /note="(acgtgcggccctgcatttc)3" FT CDS complement(115156..116793) FT /transl_table=11 FT /gene="recN" FT /locus_tag="TW111" FT /product="DNA repair protein RecN" FT /note="Similar to Escherichia coli DNA repair protein RecN FT or RadB or b2616 SWALL:RECN_ECOLI (SWALL:P05824) (553 aa) FT fasta scores: E(): 2.9e-30, 30.23% id in 559 aa" FT /db_xref="GOA:Q83NU4" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83NU4" FT /protein_id="CAD66794.1" FT /translation="MIEQISIRNFGNIAKADIDFGSDFTVITGETGAGKTMLLGALETL FT LGKPGNSKYPHNQSAQVIGIWRVPRHFENVLPCIEGKLTVSREISLSGKSVANVNGKTA FT NNSYLGKLRNKLLVVHGQFAQVRLKNPALQRQILDGYAGNTDLLKEYQLAWSELSKTNL FT ELRNIRDNLAGRRAEAIGLIQAVEEINEINPQIGEDENIKKQINILENHEQLLGNLRAA FT KQLLIDNGIIDKITELQQILCEMEGIKLQHAYGTAIDTALVTMQELSNEITKQIDTLPE FT DSTEILDEMHNRLGALRKLQKKYGPTIEDVIDFAKNALARSSTIENDDVRVQELEAKKE FT ELQKNVEYLAKKLSERRVSAARLLGDSVSLNLPCLAMPEARFEVQVLQKSHDSYGMDQV FT AMFLRTSYAGAAQPIGTGASGGEISRVMLAIEIALASVKTVPTVIFDEIDSGVGGAAAI FT EIGRRLAALARRLQVIVITHSAQVAAFATTHLLVTKTGNLSDVCSLSGENRVGEMARLL FT SGLHDSESGLEHSRELLAMAAREMQGRT" FT CDS complement(116812..117729) FT /transl_table=11 FT /locus_tag="TW112" FT /product="putative ATP-NAD kinase" FT /note="Similar to Streptomyces coelicolor probable FT inorganic polyphosphate/ATP-NAD kinase PpnK or SCO1781 or FT SCI51.21c SWALL:PPNK_STRCO (SWALL:Q9S219) (301 aa) fasta FT scores: E(): 1.2e-29, 39.09% id in 220 aa" FT /db_xref="GOA:Q83IC3" FT /db_xref="InterPro:IPR002504" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC3" FT /protein_id="CAD66795.1" FT /translation="MRVYIAHNGCLEAEPIYGTICELVAQRKMSVITDPHARNNESARN FT TDSGVVSLNQAGRNKYLDQETTSPATSRSINVPFCAGISIGGDGTFLRMARDLKNTGTP FT LFGVNMGRMGFLVDIEPEDIVNLVENIVKGEYTEEKRLPITASVQRGGKKIHDEWAVNE FT ITIERKVEGKVVDIEVFVDGCRVMDISCNGIIIATATGSTAYSFSSGGPIVWPEMKVTL FT VVPVSPHELFAKPIVLPDNRSILLKVTSRDNKVVLCSDGQVRLCLQSGDEIACHVGKVP FT VVFGRVKKGCFAEHLVKKFNLQTA" FT misc_feature complement(116847..117597) FT /note="ATP-NAD kinase Score = 192.6 E-value = 4.5e-55" FT repeat_region 117585..118355 FT /note="Coding degenerately repetitive sequence inversely FT related to non-coding repeats at FT complement(105691..107456), complement(108625..110025), FT complement(110760..111635), complement(113459..115135)" FT CDS complement(117757..124683) FT /transl_table=11 FT /locus_tag="TW113" FT /product="WiSP family protein" FT /note="No significant database matches" FT /db_xref="GOA:Q83NU3" FT /db_xref="InterPro:IPR012421" FT /db_xref="UniProtKB/TrEMBL:Q83NU3" FT /protein_id="CAD66796.1" FT /translation="MVDTKKTYSVLPVVASLTAVTLITSGLYINPQTYTHAAEQTKEAS FT QQPVDLPGRDIWLPKHISTTEQAKAFAAYFTEKTHLPTHVSGTDVYVKTYAGPDKITGT FT ISFTSSSSTTPATGKYPSAVSFLNSGDHKGWLKVSPGSLTSDVSGTYTATAEYKSADSS FT TVLSASYTFHVYDEYAVTLVTRGEASLTSALKTQYSGGLSLFGTVSQRPPACRGVDCVH FT NNQLSIPQGLQLVNPVQGILGGTVTAAPGYYTFGLVDSTKRSTATINDIVAVVEMIVQE FT HPTLDSADISVGPGSQVSYDQRPFPGRTLGGPDVTYTLTDQKPDKKPGQEIEEGKYTLP FT SGLSFNSTTGRISGTVSKTQQAHTYPLTVRTHQNYGELAKLFDLKPSQAVATIVISVVT FT PPRVTYGTTTIDSSTGTITSAIPTNLDSQALKFSIRTKPYGLDALSIDTFTGALRGNID FT SGNRLYPVPPEGVYRVVVEAKNQLGQSAYFDAPVTVGEHVSFVGRPIPSDPLDKNRTHV FT VAGVAYSLSPASGNQDNPLSQPTSVSYYRLADGTNQNATTPGSDSLPKGLSLNPNTGTI FT SGTVASTGDEIPASGTYSFRVIAVSLGGEKTEVTYTLRVEQPFVAGNSTVYVSTDQTLD FT KTTGVLTGIVGGTDVTVSLPQGTNQNATTPGSNSLPKGLSLSVSGTGESSTASARSVHL FT TGKPDGSVAPGRYLTRLSVTSGGVTKTVVLVVVVTKLALKDKARAELETQNISVYHQEG FT QPSDPIYVSPPALTGVDGETVIYTLKSGSTLPAGLSLGHEGRLTGRLLGATGVSQFTVT FT ISTRHSKSSIDLTYKITHLPVSLGKQTVTTSQGGTIVLPPSVTGLTTAGTYSIGEPDPK FT SKKKKPEEGATSPDTHDKLPKGLHLSHETGTIYGVIDKTVKTGVYSFPLTLTYGDDKNK FT KSVSAVVEIYVTQGDPIITPKNLVYYKGDTNPVKVKTLDGQDFSGLPITPTATDTNTYT FT WSLYDSGSTEGTGIIPADNTLPRGLSLDKSTGKITGTIDSSVEYGTYTFRLRATNATGG FT YGVADISLIYVTKPHTTPISPVTNPVYAAPGGRVSIPQLDGKGGFKYTLVDARDQAETV FT KKSDGPVQFGLPTGLSLNPETGYVSGTVGKTVLPGTYVFGVKVSADSLDTGRFPGSSET FT IYYALTVTTRPVLESVDGPVYKSHHVTIPANLLNAGTGTTFSLSGSSSIDPGVNRYPQG FT LSIDQSTGTLTGSVSSANPGSYTFRVLATTDGVSTEALYHLTVKTPPPFPTTTYSVVAG FT YTPHTTGREPLKDRFSVYLDLSRKYPSYTWTFGRDTVQGTTPGENTVPLGLVLYSSEGA FT LIGNVDKSVKPGLYSFDLVALDNGQYVSSLRVEITVFELDAVEYPENTLVKPGQQVSIT FT PKVPTDLDQARKLTITAGSGAVPSLKPGDGRLPLGLTITKPSLTSSSKTSDGLGAIQGV FT VDPRVEAGEYTAHIDVFQATGEQIPVGARRTVLVKIRVEGQATLLSPTQLVVTKQGASV FT SFFPHIAGGQTFAFANGTSSSITPGPNRVPAGLGINPDTGLVQGTLGTDVEAGRYTFGI FT TATGSQGTSPVTLQVTLLVSAIESRNYSVVAGRPVPVNKDTNTTGYTYALSSSSYSSVV FT AGQGRIPRGITLDRTTGNITGTVGRTVAAGLYTFGVDVFSARGSRITTVMYSVSVTDVF FT GTKPFSAAVTLGTQVSLPSGQDDGGSDFSFVNAAWSTTPGPNRVPRGVFLDPSTGSLKT FT LNPLSGVQPGIYTFTLSFGPRGRRSSYLYTLAVLPPVTLSALQGDQITDEIAIPSGITL FT SGLPKEYGIVVGADGSVTSKAITQPPGIYSLPYTTRYYGQPLYTSAPSTATLTVSSVSP FT LSADVNDVNALFDKTPEESLKETLTFAFARGTSSSTTPGPNRVPAGLGIAGPTGRVAGF FT FKTGIQNGVYTFTVDISTQSGKYLGSRLYTITIGAPGIDATVNLVKIAGIYQSTSPVIF FT FPPTQEGTYSLSSTATYSATPGPNRVPLGLLLGRADGSLTGSVYGSSPGVYTFLVESTY FT GQQLYRLTLKDTTPPPSHTQSAKPTEKPKEEKTPTESKGGGFWSKVGSGIAAPFKWIWH FT GITWPFRKLFGSRSEAPSSTTNATGNTNGKTRVKRDTQKPPEHPLKSVNEQIKTVTGAV FT NNFQKSVLTSLKDFFTYLTDTAHLKFLNSTKTGLTKINGWVTGITGPVNKYIDKIRDWG FT LLDKDHKTTGTTLKVLEAVVNPLTSWLPSPLQVLASNVLESKGLVTWTKGTATKLICLI FT PWIKTLPLCPADSGNSDKSSK" FT repeat_region 121274..121738 FT /note="rep11 inverted/repeated at 874563..875027" FT misc_feature complement(124573..124683) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.994) with cleavage FT site probability 0.943 between residues 43 and 44" FT misc_feature complement(124597..124665) FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35" FT CDS complement(124733..125194) FT /transl_table=11 FT /gene="rplI" FT /locus_tag="TW114" FT /product="50s ribosomal protein L9" FT /note="Similar to Streptomyces coelicolor 50s ribosomal FT protein L9 RplI or SCO3909 or SCH24.31 SWALL:RL9_STRCO FT (SWALL:Q9X8U5) (148 aa) fasta scores: E(): 3.6e-21, 44.66% FT id in 150 aa, and to Escherichia coli and Escherichia coli FT O157:H7 50s ribosomal protein l9 RplI or b4203 or z5812 or FT ecs5179 SWALL:RL9_ECOLI (SWALL:P02418) (149 aa) fasta FT scores: E(): 1.6e-11, 39.73% id in 151 aa" FT /db_xref="GOA:Q83IC2" FT /db_xref="HSSP:1CQU" FT /db_xref="InterPro:IPR020070" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC2" FT /protein_id="CAD66797.1" FT /translation="MTRVILVQDVNGLGSVGDVVEVKAGYSRNYLVPKGMAVRWTEGAQ FT KHIGDISAARRAREAAALQEARDIANTLTKEAVTRELRLAANAGEDGRLFGSVTAANIA FT KVLSSASGHKIDRGKIEIDSPIKTLGEHTVKVKLHPNVKVDINVVVYAE" FT misc_feature complement(124738..125008) FT /note="Ribosomal protein L9, C-terminal domain Score = 72.5 FT E-value = 6.2e-19" FT misc_feature complement(125026..125191) FT /note="Ribosomal protein L9, N-terminal domain Score = 74.5 FT E-value = 1.5e-19" FT misc_feature complement(125072..125155) FT /note="PS00651 Ribosomal protein L9 signature." FT CDS complement(125191..125442) FT /transl_table=11 FT /gene="rpsR" FT /locus_tag="TW115" FT /product="30s ribosomal protein S18" FT /note="Similar to Streptomyces coelicolor 30s ribosomal FT protein S18-2 RpsR2 or SCO3425 or SCE9.32c SWALL:R18B_STRCO FT (SWALL:Q9X8K4) (79 aa) fasta scores: E(): 2.5e-09, 52.77% FT id in 72 aa, and to Escherichia coli, Escherichia coli FT O157:H7 and Salmonella typhi 30s ribosomal protein S18 RpsR FT or b4202 or z5811 or ecs5178 or sty4749 SWALL:RS18_ECOLI FT (SWALL:P02374) (74 aa) fasta scores: E(): 2.1e-05, 43.39% FT id in 53 aa" FT /db_xref="GOA:Q83IC1" FT /db_xref="InterPro:IPR018275" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC1" FT /protein_id="CAD66798.1" FT /translation="MGYRAKGRRQPKADSVVAPPKRVSIKGLDYKDLASLKRFLSDRGK FT IRARRVTGASIQQQRQIAKAIKNAREMGVIPFKSGVSR" FT misc_feature complement(125220..125379) FT /note="Ribosomal protein S18 Score = 79.2 E-value = FT 5.8e-21" FT CDS complement(125457..126017) FT /transl_table=11 FT /gene="ssb1" FT /locus_tag="TW116" FT /product="single-strand binding protein" FT /note="Similar to Escherichia coli and Escherichia coli FT O157:H7 single-strand binding protein Ssb or ExrB or LexC FT or b4059 or z5658 or ecs5041 SWALL:SSB_ECOLI (SWALL:P02339) FT (177 aa) fasta scores: E(): 8.8e-08, 27.95% id in 186 aa, FT and to Mycobacterium smegmatis single-stranded DNA-binding FT protein SWALL:Q9AFI5 (EMBL:AF349434) (165 aa) fasta scores: FT E(): 6.6e-32, 68.29% id in 123 aa" FT /db_xref="GOA:Q83NU2" FT /db_xref="HSSP:1EYG" FT /db_xref="InterPro:IPR011344" FT /db_xref="UniProtKB/Swiss-Prot:Q83NU2" FT /protein_id="CAD66799.1" FT /translation="MDATVTVVGNLTADPELRYTATGAAVVNMTIASTPRMYDRQSGEW FT KDGEPLFLRGILWREYAINAAASLAKGMRVVAVGKLKQRNYETREGDRRTSVELEIDEI FT GPTLRYATAKCSRATQAGHGVSPDPWADSQTGQGIDSHTTRSEEITENAKNGEGAGKNE FT LNKKVLVGDNVSYEDFDSDEVPF" FT misc_feature complement(125696..126014) FT /note="Single-strand binding protein family Score = 117.9 FT E-value = 1.3e-32" FT CDS complement(126021..126323) FT /transl_table=11 FT /gene="rpsF" FT /locus_tag="TW117" FT /product="30s ribosomal protein S6" FT /note="Similar to Streptomyces coelicolor 30s ribosomal FT protein S6 RpsF or SCO3906 or SCH24.28 SWALL:RS6_STRCO FT (SWALL:Q9X8U2) (96 aa) fasta scores: E(): 9.4e-07, 35.86% FT id in 92 aa" FT /db_xref="GOA:Q83IC0" FT /db_xref="InterPro:IPR014717" FT /db_xref="UniProtKB/Swiss-Prot:Q83IC0" FT /protein_id="CAD66800.1" FT /translation="MLGSPLREYELLVSLGSEFEPEAESRVRSLFTPVEPEGVTVKHLD FT VLGVRKFAYEIKGRNDGVCVVVRLLANAGSIAEIGRQMRLTEDVIRTKLLRVGRK" FT misc_feature complement(126035..126194) FT /note="Ribosomal protein S6 Score = 26.7 E-value = 7.9e-08" FT CDS complement(126672..127589) FT /transl_table=11 FT /gene="purC" FT /locus_tag="TW119" FT /product="phosphoribosylaminoimidazole-succinocarboxamide FT synthase" FT /EC_number="6.3.2.6" FT /note="Similar to Streptomyces coelicolor FT phosphoribosylaminoimidazole-succinocarboxamide synthase FT PurC or SCO4071 or SCD25.07 SWALL:Q9RKL1 (EMBL:AL118514) FT (299 aa) fasta scores: E(): 1e-38, 40.64% id in 310 aa, and FT to Mycobacterium tuberculosis FT phosphoribosylaminoimidazole-succinocarboxamide synthase FT PurC or Rv0780 or mt0804 or mtcy369.24 SWALL:PUR7_MYCTU FT (SWALL:Q59566) (297 aa) fasta scores: E(): 1.6e-28, 38.19% FT id in 288 aa" FT /db_xref="GOA:Q83IB9" FT /db_xref="HSSP:1OBD" FT /db_xref="InterPro:IPR018236" FT /db_xref="UniProtKB/Swiss-Prot:Q83IB9" FT /protein_id="CAD66801.1" FT /translation="MTRKLEIPESRDLPDWSHIGGGKVRELYVHRQYKNILLMFASNRV FT SAFDFVLEPEIPEKGRMLTQMSNWWFRKLPAENHLLENYDQELYRDLASHIPSHILERS FT TICRKMDIIPFEFVIRGYLTGSAWADYLENNTVYGIKLKGKFRQGDRLPGPIFTPTTKS FT RTKDTPVRYEDLVNAIGLSHAQQLREMCTDYYTTAEQIARNKGLIIADAKFEFGIAEGK FT AYLADELLTADSARYWDINSWGQFDLPIERRLDSFDKQAVRDWVKCNSGKNITPQNITP FT LRLPQELIQTVYKKYKTLLAKLTG" FT misc_feature complement(126728..127547) FT /note="SAICAR synthetase Score = 194.1 E-value = 1.5e-55" FT misc_feature complement(126939..126965) FT /note="PS01058 SAICAR synthetase signature 2." FT CDS 128106..129023 FT /transl_table=11 FT /gene="menB" FT /locus_tag="TW120" FT /product="naphthoate synthase" FT /EC_number="4.1.3.36" FT /note="Similar to Escherichia coli naphthoate synthase MenB FT or b2262 SWALL:MENB_ECOLI (SWALL:P27290) (285 aa) fasta FT scores: E(): 1.3e-46, 48.76% id in 283 aa, and to FT Mycobacterium tuberculosis MenB or Rv0548c or mtcy25d10.27c FT or mt0573 SWALL:O06414 (EMBL:Z95558) (314 aa) fasta scores: FT E(): 4.5e-71, 63.39% id in 295 aa" FT /db_xref="GOA:Q83IB8" FT /db_xref="HSSP:1MJ3" FT /db_xref="InterPro:IPR018376" FT /db_xref="UniProtKB/TrEMBL:Q83IB8" FT /protein_id="CAD66802.1" FT /translation="MGESKGAPTFDTLQHVLLSELFDPDLWVAHEGFEACDVTYHTAPG FT VARIAFNRPEIRNAFRPETVDQLYAALDHARVSDKIGAVLLTGNGPSPRDGIRAFCAGG FT DQKTRRRDGYAYSDSHRSSRMHILEVQRLIRFMPKPVIALVNGWAAGGGHSLHVVCDLS FT IASLEHAKFKQTDATVASFDSGFGSAYFARQVGQKFAREVCFLAAEYDAKTALEKGAVN FT AVVAHEYLEQTGYEWARRILEQSPTSIRMFKYALNAVDDGLVGQQIFAGEATRLAYATD FT ESKEGRDAFLEKRRPDWSSFPWSF" FT misc_feature 128244..128781 FT /note="Enoyl-CoA hydratase/isomerase family Score = 125.3 FT E-value = 7.9e-35" FT misc_feature 128529..128591 FT /note="PS00166 Enoyl-CoA hydratase/isomerase signature." FT CDS 129025..130161 FT /transl_table=11 FT /gene="menE" FT /locus_tag="TW121" FT /product="O-succinylbenzoic acid--CoA ligase" FT /EC_number="6.2.1.26" FT /note="Similar to Escherichia coli O-succinylbenzoic FT acid--CoA ligase MenE or b2260 SWALL:MENE_ECOLI FT (SWALL:P37353) (451 aa) fasta scores: E(): 2.5e-10, 28.11% FT id in 345 aa, and to Mycobacterium tuberculosis MenE or FT Rv0542c or mtcy25d10.21c or mt0567 SWALL:O06408 FT (EMBL:Z95558) (362 aa) fasta scores: E(): 2.5e-29, 32.84% FT id in 338 aa" FT /db_xref="GOA:Q83IB7" FT /db_xref="InterPro:IPR000873" FT /db_xref="UniProtKB/TrEMBL:Q83IB7" FT /protein_id="CAD66803.1" FT /translation="MTKALMRGQITLDSVKRVLEDERFAICASEEPLSCGGKIMVDDAV FT CLVINTSGSTASPKRVAFSSSSLMNSARACCSVLGYGQWVLCLPKQYTAGVRVLVRSIL FT SGTKPIDISEDRFSPENFIHACRRLSCSNTFTALVPTQLSALVRVAEDDKNVAKVLSGF FT TGVIVGGQHIARSLLERSRLLGINLFTSYGLTETFGGCVYNGLPLPGVQIQIIDGRAAI FT ASPSLALGYLKENGQIDETGFFFDRGERWFHTNDLAVMNRGKLIIHGRIDRVINSGGMK FT LDLNAIETALRSLDCVEDAVLLGVKSKKWGQHFCAFIDIGDVTKADRTDCLQKINTLLS FT TFGRACRSGQIKLIHPIPRTFSGKPDRIALQRGLQNNI" FT misc_feature 129151..129649 FT /note="AMP-binding enzyme Score = 30.4 E-value = 1.5e-08" FT misc_feature 129688..129928 FT /note="AMP-binding enzyme Score = 44.7 E-value = 1.7e-12" FT tRNA 130466..130552 FT /note="tRNA Ser anticodon CGA, Cove score 52.75" FT CDS 130688..131341 FT /transl_table=11 FT /gene="ideR" FT /locus_tag="TW124" FT /product="iron-dependent repressor" FT /note="Similar to Mycobacterium tuberculosis iron-dependent FT repressor IdeR or DtxR or Rv2711 or mt2784 or mtcy05a6.32 FT SWALL:IDER_MYCTU (SWALL:Q50495) (230 aa) fasta scores: E(): FT 6.4e-29, 42.98% id in 221 aa, and to Streptomyces lividans FT and Streptomyces coelicolor iron repressor DesR or DmdR1 or FT SCO4394 or SCD10.26 SWALL:Q54343 (EMBL:Z50049) (230 aa) FT fasta scores: E(): 3.8e-32, 47.23% id in 199 aa" FT /db_xref="GOA:Q83NU1" FT /db_xref="HSSP:1DDN" FT /db_xref="InterPro:IPR011991" FT /db_xref="UniProtKB/TrEMBL:Q83NU1" FT /protein_id="CAD66804.1" FT /translation="MYLRTIVNLEEEGISPIIKARISERIGHTAPTVFQTIARMQRDGL FT LVVSSNKSLILTSKGRKIALSVVRKHRLAEVLLHDVVGLEWEHIHLEACRLEHVMSDHL FT EEHLRRILNNPSFTTYGTPIPPADSDFVEPFRDVISLSRAVIRQKARKLSVRCLGEIAQ FT QDTILLSQLSKAGLRPGGLGSFMDSQNGILSWTNSGNKFIISHYIAECIFVNQN" FT misc_feature 130688..130850 FT /note="Iron dependent repressor, N-terminal DNA binding FT domain Score = 32.7 E-value = 5.9e-07" FT misc_feature 130856..131066 FT /note="Iron dependent repressor, metal binding and FT dimerisation domain Score = 104.2 E-value = 1.8e-28" FT CDS 131520..131756 FT /transl_table=11 FT /gene="rpmB" FT /locus_tag="TW125" FT /product="50s ribosomal protein L28" FT /note="Similar to Escherichia coli 50s ribosomal protein FT l28 RpmB or b3637 or z5061 or ecs4512 SWALL:RL28_ECOLI FT (SWALL:P02428) (77 aa) fasta scores: E(): 2.9e-10, 51.31% FT id in 76 aa" FT /db_xref="GOA:Q83IB6" FT /db_xref="InterPro:IPR001383" FT /db_xref="UniProtKB/Swiss-Prot:Q83IB6" FT /protein_id="CAD66805.1" FT /translation="MSSVCQVTGASPGFGYAVSHSHRRTKRRFDPNVRRRTFYVATLGR FT RVTLNVSVKGLRLIDKRGIDAVVRDLIKKGVKL" FT misc_feature 131526..131706 FT /note="Ribosomal L28 family Score = 75.1 E-value = 1e-19" FT CDS 131756..131926 FT /transl_table=11 FT /gene="rpmG" FT /locus_tag="TW126" FT /product="50s ribosomal protein L33" FT /note="Similar to Escherichia coli 50s ribosomal protein FT l33 RpmG or b3636 SWALL:RL33_ECOLI (SWALL:P02436) (54 aa) FT fasta scores: E(): 3.6e-07, 43.13% id in 51 aa, and to FT Mycobacterium tuberculosis 50s ribosomal protein l33 type 1 FT RpmG or Rv2057c or mt2117.1 or mtcy63a.03 SWALL:R331_MYCTU FT (SWALL:O86356) (54 aa) fasta scores: E(): 3.1e-17, 78.84% FT id in 52 aa" FT /db_xref="GOA:Q83IB5" FT /db_xref="InterPro:IPR018264" FT /db_xref="UniProtKB/Swiss-Prot:Q83IB5" FT /protein_id="CAD66806.1" FT /translation="MARKRQDVRPIVKLKSTAGTGFTYVTRKNRRNDPDRIVLKKYDPI FT IRRHTEFREER" FT misc_feature 131780..131921 FT /note="Ribosomal protein L33 Score = 42.9 E-value = FT 5.2e-10" FT CDS 131927..132232 FT /transl_table=11 FT /gene="rpsN" FT /locus_tag="TW127" FT /product="30s ribosomal protein S14" FT /note="Similar to Escherichia coli 30s ribosomal protein FT S14 RpsN or b3307 or z4677 or ecs4172 SWALL:RS14_ECOLI FT (SWALL:P02370) (100 aa) fasta scores: E(): 5.8e-12, 47% id FT in 100 aa, and to Mycobacterium tuberculosis 30s ribosomal FT protein S14-2 RpsN2 or Rv2056c or mt2117 or mtcy63a.04 FT SWALL:R14B_MYCTU (SWALL:O86355) (101 aa) fasta scores: E(): FT 1.2e-21, 61.38% id in 101 aa" FT /db_xref="GOA:Q83IB4" FT /db_xref="InterPro:IPR018271" FT /db_xref="UniProtKB/Swiss-Prot:Q83IB4" FT /protein_id="CAD66807.1" FT /translation="MSKLSKIVKNEKRKVIVARYAARRQELKRIIAAPGTAPERRDEAQ FT AALQKLPRDASPVRVRSRDVVDGRPRGILSRFGVSRIRFREMAHRGELPGITKSSW" FT misc_feature 131927..132227 FT /note="Ribosomal protein S14p/S29e Score = 114.0 E-value = FT 2e-31" FT CDS 132298..132579 FT /transl_table=11 FT /gene="hup" FT /locus_tag="TW128" FT /product="DNA-binding protein HU-alpha" FT /note="Similar to Escherichia coli DNA-binding protein FT HU-alpha HupA or b4000 or z5576 or ecs4923 SWALL:DBHA_ECOLI FT (SWALL:P02342) (90 aa) fasta scores: E(): 7.7e-08, 37.77% FT id in 90 aa, and to Streptomyces coelicolor, and FT Streptomyces lividans DNA-binding protein HU 1 Hup1 or Hup FT or SCO2950 or SCE59.09 SWALL:DBH1_STRCO (SWALL:O06447) (93 FT aa) fasta scores: E(): 5.1e-13, 50.54% id in 91 aa" FT /db_xref="GOA:Q83IB3" FT /db_xref="HSSP:1HUE" FT /db_xref="InterPro:IPR000119" FT /db_xref="UniProtKB/TrEMBL:Q83IB3" FT /protein_id="CAD66808.1" FT /translation="MVSLNRTELVAKVAETSGVSRATVNSVIEETFAVFAETVRAGGKV FT TIPGWCSVTRSHRAARTGRNPQTGKTVEIPAGYSVRIAPGSKLKAAVK" FT misc_feature 132307..132574 FT /note="Bacterial DNA-binding protein Score = 97.6 E-value = FT 1.8e-26" FT misc_feature 132319..132384 FT /note="Predicted helix-turn-helix motif with score FT 1013.000, SD 2.64 at aa 8-29, sequence FT ELVAKVAETSGVSRATVNSVIE" FT CDS 132629..134734 FT /transl_table=11 FT /locus_tag="TW129" FT /product="putative integral membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein Rv0102 or mt0111 or mtcy251.21 SWALL:Y102_MYCTU FT (SWALL:Q10897) (661 aa) fasta scores: E(): 8.5e-38, 31.79% FT id in 478 aa, and to Streptomyces coelicolor putative FT integral membrane protein SCO1215 or 2SCG58.15 SWALL:Q9FC98 FT (EMBL:AL391017) (316 aa) fasta scores: E(): 3.3e-37, 40.13% FT id in 304 aa" FT /db_xref="InterPro:IPR019108" FT /db_xref="UniProtKB/TrEMBL:Q83NU0" FT /protein_id="CAD66809.1" FT /translation="MARLLSARFFSILIVFFALSFFLASFVLPRLLGGFDINWALVSVT FT GALRFLVAILVGCLVSIAYSLSPRFPEYGKLLIVARTLSCCVVPVVFFCILFAFLTEKA FT EFSGLNFETYLTGPGFVWIIVLALVLLISLALLFCKKRIQIAVISTITLLLLIPLAFSE FT HSGHSTVSANVSQHVTDYQGSVSDKSHHAHHSHNHSHNHSQGETRSAHDVPLDAIGASR FT TPAMHGGSHGAMGASLVYAISISVLAGVIFSMLYITGLYFARIKHIKSSVQIMPQRFFS FT ITNRLSVLSMFLLLFAFFSDAVTAMPYISSEFTPYGILSATKIALFLLLALCALYIHFF FT YFIKSRMTCALIVILACEAVITGLIFLITASAVTQIPQASVSDRTPTPAELLTGQILPP FT RESFTNYLSIWMIDPLWLSICVVLAFFYLLGVIKLHRRGDRWPWLKTVSWLFAVLVMFY FT VTNGGVAVYGMYLFSAHMVMHMTLGAIVPIFLVVASPVTLLLRAVPARRDGSFGPREWI FT LFFLNTRFIQFISLPPIAAAIFILSMFIFYFTDLLQFGIQNYLGHQVMMFHFLLSGYLF FT AQSILVTDPSRHRFSIPSRMLVLVLAMATHAFFGIAIMSSRYLFLPEWFGAMGRTWGSP FT PLVDQQMGGALAWGTTEIPTILLVTFLFFKWFKQDQREALRRDRAEDRNGDKALVAYNE FT YLARLQG" FT misc_feature 132629..132730 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.974) with cleavage FT site probability 0.443 between residues 34 and 35" FT misc_feature order(132647..132715,132758..132826,132863..132931, FT 132974..133042,133061..133114,133340..133408, FT 133487..133555,133598..133657,133676..133744, FT 133847..133915,133973..134041,134069..134137, FT 134198..134266,134309..134377,134414..134482, FT 134561..134629) FT /note="16 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29, 44-66, 79-101, 116-138, FT 145-162, 238-260, 287-309, 324-343, 350-372, 407-429, FT 449-471, 481-503, 524-546, 561-583, 596-618 and 645-667" FT CDS 134760..136832 FT /transl_table=11 FT /locus_tag="TW130" FT /product="putative helicase regulator" FT /note="Similar to Anabaena sp. hypothetical protein Alr4398 FT SWALL:Q8YP09 (EMBL:AP003596) (1075 aa) fasta scores: E(): FT 9.6e-17, 26.54% id in 584 aa, and to Drosophila FT melanogaster IswI protein or cg8625 SWALL:ISWI_DROME FT (SWALL:Q24368) (1027 aa) fasta scores: E(): 2.3e-15, 26.16% FT id in 474 aa" FT /db_xref="GOA:Q83IB2" FT /db_xref="InterPro:IPR014021" FT /db_xref="UniProtKB/TrEMBL:Q83IB2" FT /protein_id="CAD66810.1" FT /translation="MTNAVIKDRTSHLLSALARTVREVEMSLVRKRIGPSSVMRFHAVA FT LLLRQERARVKSDPDITDTVRTELIRRLDGLAAVMVRIAARDTALMSIVTPDAPVSDGA FT LLYRRRLLSQIGVIDSDGESSEIREAAPPPPSLELYPQSVKMYHATHIFRPPGPDMESD FT LVPIIRLANWDLVGSVFKAFSQGGASVCKSLPAPSPFLDRLAPDGLSMMPHQAGFVESA FT RLGHRSFLLADEPGLGKTAQSLLAAGVTNSFPLLVVVPNVVKLNWVREAKMWLPGRRAT FT IISGDDLDAFADIFVINYEMLDRHMLWMVDFGFAGMVVDEAHLIKNFSSQRSGNVLALA FT QHIRKKCCNPLMIALTGTPVINSVEDFRALWLFLGWLAGPRGRDLSPVFVSELEKTGLT FT PEDPGFSETVRDVMGHLGIVRRRKTQVAKDLPERMVVDLPVELDGDAFRSVKNAEDDLA FT DALYAQYISLKHLRIDDYQIRLKAVERFAVESKDSSALNIFSIVRKIGITKAPLAIDFT FT IQMLDSVGKIVFFAKHIEVMNMAEEMFCQQGIRSVSIRGSQTPNDRKNALRTFDEDPDT FT RVAICSLTAAGLGINLQVASNVVLSELSWTAAEQGQAIDRLHRIGQTEPVTAWRILGAG FT TVDIRMAALVDSKSNDAILSLDGGDMREVQQESLHIRSLLDLLDDRIRKAEQHVE" FT misc_feature 135399..136293 FT /note="SNF2 family N-terminal domain Score = -26.6 E-value FT = 2.3e-08" FT misc_feature 136401..136620 FT /note="Helicase conserved C-terminal domain Score = 52.2 FT E-value = 8.2e-13" FT CDS 136972..138165 FT /transl_table=11 FT /gene="tufA" FT /locus_tag="TW131" FT /product="elongation factor TU-1" FT /note="Similar to Escherichia coli elongation factor TU FT (TufA or b3339) and (TufB or b3980) SWALL:EFTU_ECOLI FT (SWALL:P02990) (393 aa) fasta scores: E(): 1.1e-103, 70.38% FT id in 395 aa, and to Micrococcus luteus elongation factor FT TU Tuf or TufA SWALL:EFTU_MICLU (SWALL:P09953) (396 aa) FT fasta scores: E(): 6.3e-119, 82.02% id in 395 aa" FT /db_xref="GOA:Q83NT9" FT /db_xref="HSSP:1ETU" FT /db_xref="InterPro:IPR004160" FT /db_xref="UniProtKB/Swiss-Prot:Q83NT9" FT /protein_id="CAD66811.1" FT /translation="MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISRVLSERLPSNTN FT VKQDFDAIDSAPEERQRGITINISHIEYETEKRHYAHVDAPGHADYIKNMITGAAQMDG FT AILVVAATDGAMAQTREHVLLAKQVGVPYLLVALNKADMVSDEEILELVELEVRELLST FT HGFDGENVPVVRVSGLKALEGDQKWGDAVMELMKAVDESIPDPVRDRDKPFLMPIEDVF FT TITGRGTVVTGRAERGVLAVNSEVEIVGIRPTQKTTVTGIEMFRKQLDEAWAGENCGLL FT LRGTKREDVERGQVVVKPGSVTPHTKFEGKAYILSKDEGGRHNPFYSNYRPQFYFRTTD FT VTGVITLPEGTEMVMPGDTISITVDLIQPIAMEEGLGFAIREGGRTVGAGTVVKILE" FT misc_feature 136999..137590 FT /note="Elongation factor Tu GTP binding domain Score = FT 317.3 E-value = 1.2e-92" FT misc_feature 137026..137049 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 137131..137178 FT /note="PS00301 GTP-binding elongation factors signature." FT misc_feature 137626..137860 FT /note="Elongation factor Tu domain 2 Score = 105.9 E-value FT = 5.4e-29" FT misc_feature 137872..138157 FT /note="Elongation factor Tu C-terminal domain Score = 190.4 FT E-value = 2e-54" FT CDS complement(138453..140111) FT /transl_table=11 FT /locus_tag="TW132" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="GOA:Q83NT8" FT /db_xref="InterPro:IPR003342" FT /db_xref="UniProtKB/TrEMBL:Q83NT8" FT /protein_id="CAD66812.1" FT /translation="MIAYWGMIFGVVVLATLLRFYNLSDPKTLIFDETYYVKDAYTLYK FT NGYESEWPRDMKPEDIDKRFVSGDTDFFTNEPEFLAHPHLGKYIIGAGIELFGVRSQFG FT WRIAVALIGVLGVFMTAVIAARLFESTLIGGIAGFLFAIENNAIVMSRVAILDNVLMII FT SLIAVWCVLLDRQWYRKAMSKWVQNRSKHLSQDAKGNYLVSGPLVWWRPWLALAAVLMG FT MAASVKWSGIFYYFGIIPYITAIDWTTRKQLGIKYRFQGTFYQVLVSGISSVIISVFVY FT IALWANYFIVGGWGSSWATYPGNGWAGPLAWVPKIFQSWVNFQVTMYRFNSTLTTPHIY FT EAPVYTWPFLIRPTNMYWTKIGDDVRVIIGLPNPLLWWAAVALFIIFALIAIFAPSRRD FT WRMNFILMTLAGGYFPWFLYVNRTIFHFYTIVFEPFMIIMIAAAIYKILEIKTENRLLP FT TPWVGTRRFEYGSRVLAALRGSGNRVREACFVMPARIASLDIAPVMQAPLLRLMLVVTF FT LLAATVCGFVILPINMAWPVHYKYWESLMILPSWK" FT misc_feature complement(order(138507..138575,138777..138845, FT 138855..138914,138933..138992,139257..139325, FT 139386..139454,139593..139652,139665..139724, FT 139737..139805,140043..140102)) FT /note="10 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 4-23, 103-125, 130-149, FT 154-173, 220-242, 263-285, 374-393, 400-419, 423-445 and FT 513-535" FT misc_feature complement(139244..140093) FT /note="Dolichyl-phosphate-mannose-protein FT mannosyltransferase Score = 3.2 E-value = 0.00012" FT CDS 140623..141990 FT /transl_table=11 FT /gene="manA" FT /locus_tag="TW133" FT /product="mannose-6-phosphate isomerase" FT /EC_number="5.3.1.8" FT /note="Similar to Escherichia coli mannose-6-phosphate FT isomerase ManA or Pmi or b1613 SWALL:MANA_ECOLI FT (SWALL:P00946) (391 aa) fasta scores: E(): 2.9e-15, 30.23% FT id in 387 aa, and to Streptomyces coelicolor FT mannose-6-phosphate isomerase ManA or SCO3025 or SCE34.06c FT SWALL:Q9KZL9 (EMBL:AL353862) (383 aa) fasta scores: E(): FT 1.5e-22, 34.36% id in 323 aa" FT /db_xref="GOA:Q83IB1" FT /db_xref="InterPro:IPR016305" FT /db_xref="UniProtKB/TrEMBL:Q83IB1" FT /protein_id="CAD66813.1" FT /translation="MRRPDIFLLKNAPMNYDWGDCTAIASLQGRQPTSRPEAEIWFGTH FT PRSPAYLSDGRLLASALEEHGISISYLVKLLAAAKPLSIQVHPNSAQARAGFAREKHLD FT SASKNYRDRYEKSEMLIAISDTFSLLCGFRPKDELSETLNHFSLVSKKFKIMRDLYEQH FT GLKCAIAWFFENANQSDIDLLCEGRMPYESQNTTISDLKKHHVNEPGFVLAVLMSRVNI FT TRGQSVFVQAGTLHSYLKGFGVEIMTNSDNVIRAGLTTKHIDTVELQKVALFKSEPVCL FT LQPHISNSGASRRFCTPYFTVEEVTLSGNEGSCLSSTIGNCAYCNRDSDSDLTSVLQHD FT LDQKHDGMTEPSPGLSEGIHACNSGITCTSESISKSATAIPGGTFGGSGYTLRGTGLVL FT VTAGVVHLSSGDEELIVRSGFAAFVIDPSPSGGVFLTGCGVCYIVTDDNQFDIIAS" FT misc_feature 140638..141607 FT /note="Phosphomannose isomerase type I Score = 64.2 E-value FT = 2e-16" FT CDS 142042..142350 FT /transl_table=11 FT /locus_tag="TW134" FT /product="WhiB-like regulatory protein" FT /note="Similar to Streptomyces griseocarneus WhiB-STV FT protein SWALL:Q06387 (EMBL:X68708) (87 aa) fasta scores: FT E(): 1.6e-20, 80% id in 70 aa, and to Streptomyces FT coelicolor regulatory protein WhiB or SCO3034 or SCE34.15C FT SWALL:Q53963 (EMBL:X62287) (87 aa) fasta scores: E(): FT 1.6e-20, 80% id in 70 aa" FT /db_xref="InterPro:IPR003482" FT /db_xref="UniProtKB/TrEMBL:Q83NT7" FT /protein_id="CAD66814.1" FT /translation="MSDNLPIPDDWHIDPVLLGIPGLRGGFDWRARALCAQADPESFFP FT EKGGSTREAKKVCSSCAVRSECLEYALENDERYGIWGGTSERERRILRQRRAASGLA" FT misc_feature 142126..142315 FT /note="Transcription factor WhiB Score = 125.1 E-value = FT 8.9e-35" FT CDS 142512..144908 FT /transl_table=11 FT /locus_tag="TW135" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces aureofaciens transmembrane FT protein WhiB2 SWALL:Q53785 (EMBL:L22864) (1219 aa) fasta FT scores: E(): 1.5e-06, 21.76% id in 896 aa, and to FT Streptomyces coelicolor putative integral membrane protein FT SCO3033 or SCE34.14c SWALL:Q9KZL1 (EMBL:AL353862) (1268 aa) FT fasta scores: E(): 2e-06, 24.06% id in 939 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NT6" FT /protein_id="CAD66815.1" FT /translation="MRFPPGYNRARALNAACLKCPDTDFYWFLNTRIVAAPTALEYLLN FT TIEVSPGASVAAPKILNDTGVFFDYGQSITTGGRAVHLVQDELDQGQHDDKVDTMGANY FT AGMLVHRSCFEAIKGFDPGFSEYEQGLDFCIRARLSGARVSLSPRSVVTHVGTGLRSYR FT VQEGYIQKRTGQLRRQIVYAPFVKSVLLWFSLIPRGVLWFLASLLTRRSALKEAWAHIK FT LAFLPISLARSRKISNRQNSLRALSVLMQKPKREFMSYEKLDFFFRNGLVIVLIFVFIG FT FVVFLPFLAHPALSGGSLLPINLSFYQMWRMTAVYVFLDGVYPADPFNIIPALLGSLTF FT WDTNFSILLLYFVALPLSCTAAWLCASRLLSSPRTIAFSAALYSLSPSLWLGLYNGNLQ FT GIVVHICLPFLCFLMLGIKTFRTLSLASLLFAFITVASPSIFLPLTVLVLIVAIATATF FT RMLFIVLPVIVAFIPLFLVQPLRVNLLADPVLSSTNLFSSIFGLGNIFTTAHLSLFLLV FT LPIIFLILMGLWKTYSSLPFLLITFVGFVNSVIWADVWQGPSFSLAWLGITGAAAIGFT FT SIRCIKRMIALVSVGALGAFFVYIPYATKIWQAQSPVVSTTSAVNLPAYVLAEANSNSN FT IGTLIVEPVSEKEIRVKVARGAVFGFGSQNTKLISGANPQSSDLANLAVNLVMSGNVDI FT AEGMKRLNLEMLLLSGDKYGFSANINANSMFEAAGNTPFGKLWRLKDRLPPLGQATFPP FT YYWLSPIVFLLLFLVGVFGRSSRKPPEEMGIDLEDQFAEPGYALT" FT misc_feature order(143049..143117,143304..143372,143457..143525, FT 143544..143603,143631..143690,143709..143762, FT 143805..143873,143892..143951,144027..144095, FT 144108..144176,144189..144245,144264..144332, FT 144759..144827) FT /note="13 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 235-257, 320-342, 371-393, FT 400-419, 429-448, 455-472, 487-509, 516-535, 561-583, FT 588-610, 615-633, 640-662 and 805-827" FT CDS 144961..146340 FT /transl_table=11 FT /locus_tag="TW136" FT /product="putative secreted protein" FT /note="Similar to Streptomyces coelicolor putative secreted FT protein SCO3032 or SCE34.13c SWALL:Q9KZL2 (EMBL:AL353862) FT (506 aa) fasta scores: E(): 0.01, 24.83% id in 294 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NT5" FT /protein_id="CAD66816.1" FT /translation="MKIFPKILNCFILVLLPAIVFLFSGVHITTAVGVRHKTKVTSIEL FT RLSCPGSLVGVGGVHARGISFVPLGNPSVLYAASQAGLLKAEHPSGVMLRGGYGTSGSQ FT IQGLSSDRVKGLAAASCQQPRQESWLLGGATGVFDNTLLILGNPSDSQTSVSFTVYSGN FT EKKFSSGVPVPSRSLRFVNLAGIAPGLSRIAVQVKSDDVPVYSVLQHSIVKGAVPMGVS FT YVSTGNIDKSQYIPGVIINDNTINDNDNPQILLRLFVPGKDDADVSVSVVSKTTPGTAL FT TAHVTGGSIRDIPISGLTSSSYFISITSSKPLLASALSSMSFQSGARDFAWYPATHATS FT ADTFIAVPSRGVLALQNTLDQSQSVKLESLNGFSDSFPSGFVNTSHVFVPKQPEVTNST FT VIHLDRSGVATHPVSRGFYRLSHKGQVAFSLAFVNSEGIAMYNPPTGDTRPDGITVDVL FT Q" FT misc_feature 144961..145062 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.998) with cleavage FT site probability 0.606 between residues 34 and 35" FT misc_feature 144979..145047 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29" FT CDS 146782..148212 FT /transl_table=11 FT /gene="manB" FT /locus_tag="TW137" FT /product="phosphomannomutase" FT /EC_number="5.4.2.8" FT /note="Similar to Escherichia coli phosphomannomutase ManB FT or RfbK or RfbK2 SWALL:RFK9_ECOLI (SWALL:P37755) (456 aa) FT fasta scores: E(): 4.3e-48, 34.44% id in 450 aa, and to FT Streptomyces coelicolor phosphomannomutase ManB or SCO3028 FT or SCE34.09c SWALL:Q9KZL6 (EMBL:AL353862) (454 aa) fasta FT scores: E(): 6.8e-88, 51.96% id in 458 aa" FT /db_xref="GOA:Q83IB0" FT /db_xref="HSSP:1K35" FT /db_xref="InterPro:IPR016055" FT /db_xref="UniProtKB/TrEMBL:Q83IB0" FT /protein_id="CAD66817.1" FT /translation="MPQRGGLCSSIHSYSGRSVSVFKAYDVRGLVPEQLTTDISRAIGA FT AYIDSLGCSSIVVGRDMRPSSKELFYAFAEGCTARGASVIDIGLCSTDAVYYASGAWNI FT PAAVFTASHNPPEYNGIKFCRPGAQGIGYTTGLSDVEKISDKYLLKGIPHAETKGKVVK FT KSVGREYAEYICNLVGPLQKPLKVVIDAGNGMAGKMVPIVMQSALTDIEILPLYFELDG FT TFPNHEANPFDPKNLVDLQHAVKETGADIGLAFDGDADRCVVIDEMSNPVTPSSIASIV FT VGRILKQYGNAKATIVHNLLVSRGFAESVISRNSENRLVRTRVGHSFIKDIMHKTNALF FT GCEHSAHYYFRDFWGADNGMLAALYVMAELCESPMPMSVLSRKYTPYFQSGETNYRVHN FT PDMTMSAIRQAFPGAYVEFLDGMTLYESVKDPGPERFWWLNVRKSNTEPLLRLNVEAQT FT EDLMRLVRDKAVKIITGG" FT misc_feature 146827..147244 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain I Score = 132.2 E-value = 6.9e-37" FT misc_feature 147292..147592 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain II Score = 101.0 E-value = 1.7e-27" FT misc_feature 147598..147940 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain III Score = 67.0 E-value = 2.8e-17" FT misc_feature 147985..148207 FT /note="Phosphoglucomutase/phosphomannomutase, C-terminal FT domain Score = 15.5 E-value = 0.0008" FT CDS 148563..149258 FT /transl_table=11 FT /locus_tag="TW138" FT /product="conserved hypothetical protein (possible FT ATP-binding)" FT /note="Similar to Corynebacterium glutamicum predicted FT amidophosphoribosyltransferases Cgl0757 SWALL:BAB98150 FT (EMBL:AP005276) (196 aa) fasta scores: E(): 4.4e-06, 23.98% FT id in 196 aa, and to Deinococcus radiodurans competence FT protein ComF, putative dr1389 SWALL:Q9RUJ7 (EMBL:AE001984) FT (219 aa) fasta scores: E(): 2.2e-05, 27.17% id in 195 aa" FT /db_xref="UniProtKB/TrEMBL:Q820Z3" FT /protein_id="CAD66818.1" FT /translation="MSNLFYPTSCPCCGMQDTTLCDLCFARLAERPYRESLAGLDVISC FT CDYTPTARAFITAYKVMKRMTLAKFMGLIIANQLNVFSSEYGNYSVITMPSTRLSWRSR FT GFHPVDHALKTIGVEPVDLLCFRKQPKDQAFLDRRERMANMFGTLQVKKISTYSKNLLF FT VDDVMTSAATLLEVHRAVSLTGKTLIGAVVLFRTRAKYPLGYNVRNKRSDSQSLKCTNH FT FIPTFSITR" FT misc_feature 149100..149123 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 149502..152045 FT /transl_table=11 FT /gene="secA" FT /locus_tag="TW139" FT /product="preprotein translocase SecA subunit" FT /note="Similar to Streptomyces griseus preprotein FT translocase SecA subunit secA SWALL:SECA_STRGR FT (SWALL:P95759) (940 aa) fasta scores: E(): 5.6e-138, 60.32% FT id in 862 aa" FT /db_xref="GOA:Q83NT4" FT /db_xref="HSSP:1NKT" FT /db_xref="InterPro:IPR011116" FT /db_xref="UniProtKB/Swiss-Prot:Q83NT4" FT /protein_id="CAD66819.1" FT /translation="MSVKLLERILRAGEGRTLKRLRNIAHTVNAIEDEYKGCTDGELRT FT FAFDLKVRHQNGESLDSILPEAFAMVREASSRTLGLRHFDVQIMGGAALHMGYIAEMFT FT GEGKTLVATLPAFLNSLSGNGVHIVTVNDYLAGYHSQQMGRVYKVLGLETGVILADQDP FT STRAQQYRADITYGTNNEFGFDYLRDNMAWSCAERVQRGHNFVILDEVDSILIDEARTP FT LIISGSSSGEVSRWFVEFAGIARALTAGEDYDVDERKHTVGVLEPGIAKVEDLLGISNL FT YESVNTPLISFLNNSIKAKELFKRDRDYVVLDGEVMIVDEHTGRILSGRRYNEGLHQAI FT EAKEGVEIKAENQTLATVTLQNYFRLYKKISGMTGTAVTEASEFMSTYKLPVVSIPTNK FT PNIRKDHPDVVYKNEQIKFENLADHVRECYTRGQPVLIGTTSVEKSEYVSKLLSKRGVR FT HEVLNAKNHAKEARIVAEAGRLRAVTVATNMAGRGTDIILGGNPEVLTAVELRRKGLDP FT SKDPERYEQAWSSAFPKLHRRTREEAEKVIEAGGLMVIGTERHESRRIDNQLRGRSGRQ FT GDPGESRFYLSLTDDLMRKFNPGAASALAARVPDDTAIESKLVSRAIRSAQAQVESLNA FT ETRKNVLKYDDVLNRQRAAIYTDRSRILEGGDIADRVQAFLSDAIEEIINSHAVTAWDF FT DALWADLKTIYPVGISIEELTDEAGGMGRITPDFVMREILSDAKFAYEKRESEIGPESM FT RDLERKVVLSVIDRCWRDHLYEMEYLKEGIGLRAMAQRDPLVEYQKEGFDMFEAMMGRI FT REESIGYLFNIDAQVSSNSPSDARNRPIEHDDNAV" FT misc_feature 149517..150762 FT /note="SecA protein, amino terminal region Score = 855.6 FT E-value = 1.1e-254" FT misc_feature 150948..150995 FT /note="PS01312 Protein secA signatures." FT CDS 152632..152805 FT /transl_table=11 FT /locus_tag="TW140" FT /product="hypothetical protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83IA9" FT /protein_id="CAD66820.1" FT /translation="MFLETLREHCRRCRLHTPHTIAEGVVTGVHKDHVHLKKDIDHELF FT FPICNLIAIELL" FT CDS 152950..153696 FT /transl_table=11 FT /locus_tag="TW141" FT /product="putative membrane/secreted protein" FT /note="No significant database matches" FT /db_xref="InterPro:IPR013974" FT /db_xref="UniProtKB/TrEMBL:Q83NT3" FT /protein_id="CAD66821.1" FT /translation="MKIRSKWFPDTRILIGLALIAASFIGVFFVIKTNNSKSQVYVATR FT PLSIGDKFDAKQFSIVEANLGANLDKYITPGSLPNAVFNRPIMPGEFLPKSALVPVIDK FT DIVAVVLRIAGDLPGDVKEGDLVDVWAAVKIKEEGFWQSELIAKTLRVSRVIVSTSQFD FT PRGTTKVEVQASRDRLSYLLNAIANQDKVSIVRASHKEIELLRSASTPRTLDEQDKQNV FT GETPDTNPRGPDEKDSNSESIHEGHE" FT misc_feature 152950..153063 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.996) with cleavage FT site probability 0.480 between residues 38 and 39" FT misc_feature 152986..153042 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-31" FT CDS 153705..154487 FT /transl_table=11 FT /locus_tag="TW142" FT /product="putative regulator" FT /note="Similar to Bacillus subtilis sporulation initiation FT inhibitor protein SoJ SWALL:SOJ_BACSU (SWALL:P37522) (253 FT aa) fasta scores: E(): 0.00051, 30.88% id in 136 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NT2" FT /protein_id="CAD66822.1" FT /translation="MGKTIAIWGPAGSPGRTTLSINIAATLASYGKKVILIDLDTFGGV FT VSIYLGLDDQKSGLAAICYRADSRSFTPEDLLNIAIKVPIRGGLFYFLSGIAHHSRWPE FT INQPSLLRVIGSAKSAFDYVVMDLSFALDSVGQDTRGRLNYTLMGSGDFLVMVGRGDPI FT GICRFIRAWPEVPKAQNGRSLSIIPVINMVRHTAVGSRPTKQLREVICEYTSFQQVWQI FT DFDQKVCDALLLRGKTIVDCMQNSSVAMQIASIGRVLQ" FT misc_feature 154395..154418 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS join(154524..154733,154735..155181) FT /transl_table=11 FT /locus_tag="TW143" FT /product="hypothetical phase-variable integral membrane FT protein" FT /note="No significant database matches. Frameshift at FT potentially variable G(11) tract after aa 70" FT /db_xref="UniProtKB/TrEMBL:Q83IA8" FT /protein_id="CAD66823.1" FT /translation="MSAFHSKVSPHVSSVVPTTNLTYKPNTRNIQVIRGIFKVITLCLI FT KTLIITLCTMTFQTQTYAAQIQTSGGGARSLAEQEHNRTKRGANLFGLFASAVGTAVKT FT KLKELKSTVQRKGKELQNTITRPLQQAVDNTVQTVVAQAAQSATQAVQSQPVQAQVQQL FT TSTATSAVSTLANTVLDDLLGRAKETAKTVGYSLLGVLAAALTGFAIFAIVKWGR" FT misc_feature order(154611..154679,155098..155166) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 30-52 and aa 131-153" FT repeat_region 154731..154741 FT /note="(g)11" FT misc_feature 155098..155166 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 131-153" FT CDS 155275..158181 FT /transl_table=11 FT /gene="gcvP" FT /locus_tag="TW144" FT /product="glycine dehydrogenase [decarboxylating]" FT /EC_number="1.4.4.2" FT /note="Similar to Escherichia coli glycine dehydrogenase FT [decarboxylating] GcvP or b2903 SWALL:GCSP_ECOLI FT (SWALL:P33195) (956 aa) fasta scores: E(): 4.4e-106, 48.71% FT id in 973 aa, and to Mycobacterium tuberculosis probable FT glycine dehydrogenase [decarboxylating] GcvP or GcvB or FT Rv1832 or mt1880 or mtcy1a11.11C SWALL:GCSP_MYCTU FT (SWALL:Q50601) (941 aa) fasta scores: E(): 2e-114, 51.27% FT id in 981 aa" FT /db_xref="GOA:Q83IA7" FT /db_xref="InterPro:IPR015421" FT /db_xref="UniProtKB/Swiss-Prot:Q83IA7" FT /protein_id="CAD66824.1" FT /translation="MHERHIGPSQEEIDHMLGFLGYKSLDDLMHAALPNGVQSPPDIKI FT PSHDELTCLTQLAAFAKMNRIKTSMLGQGFYNCITPAVIRRNILENPSWYTSYTPYQPE FT ISQGRLEMLINFQTMICDLTGLEIANASMLDEASCAAEAMLLAKRVSRSSSNKYLVHNG FT VFPHIRRVLETRADAVGVEIVDLPEGQSIDFDHFGVYAQYQSASGKLLDLRPLFSRSKR FT AGAICVIGCDLLMLTLFTSPGELGADIAFGSAQRFGIPMNFGGPLASFLAARKAMERSL FT PGRLVGVSVDADSNHAYRLTLQTREQHIRREKATSNICTATVLMAIAAVAFAQHHGPKG FT LRAIAHRINTVAVGFARLLKQTAFRVSSLDIFDTIEINNPTQVCVEAESKYDLLFWKVD FT DNKLRITFDEVTARLDGDLPERLSKVFGISPDKIRDLGCNYDSCDCSFYGDLQQAREGL FT SSVASRNISVHSDLARHPLRRFSGYLKHPVFNNYTGEVALMRYLKALSDKDFALDRGMI FT PLGSCTMKLNAAFQLEPVLWPEFANLHPFAPLGDADGTLQIIDQIETWLANLSGYDAVS FT LQPTAGSQGELAGLLAIRGYYKSLNLDRDVCLIPASAHGTNAASAVLAGMRVVVVACDQ FT QGNIDLDDLRLKASKNAHALAALMVTYPSTHGVYEDNISEVCSVVHKYGGQVYVDGANS FT NALIGYLRTGDFGGDVSHLNLHKTFGIPHGGGGPGIGPVVAKAHLAPFLPFRNRVHKPS FT TDLPAVKHMGGPIASSDYGFAGALYISWAYIFCLGSQGMKRCTAVAVLVANYIAKQLSD FT TFPVLYTGKNNLVAHEFIMDFREVTRVSGITVDDVCKRLIDYGFHAPTMSFPVPGTLMV FT EPTESEPFSEIQRFIKTIRSIRAEIDRVIDKTYDPDNNPLKRAPHTLEQIASDKWDRPY FT SRRTGIVYTSGKYWPASARIDNAYGDRNIFCTCPDLPD" FT misc_feature 155281..156550 FT /note="Glycine cleavage system P-protein Score = 572.6 FT E-value = 1.8e-169" FT CDS 158391..159971 FT /transl_table=11 FT /locus_tag="TW145" FT /product="putative ABC transporter substrate-binding FT protein" FT /note="Similar to Streptomyces coelicolor putative peptide FT transport system secreted peptide-binding protein SCO5117 FT or SC9E12.02 SWALL:Q9F353 (EMBL:AL391751) (544 aa) fasta FT scores: E(): 1.2e-51, 33.57% id in 551 aa" FT /db_xref="GOA:Q83NT1" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q83NT1" FT /protein_id="CAD66825.1" FT /translation="MRKGFSRVFTFTAVSAVLFVTACFGGKPTDSYVNVNTTKISTGLV FT PANSNELSAHRILSMLFSGLVYIDKDARIQNEVAKSIETADNRVWTITLREDFKFSNGE FT KVTAKSFVDAWNFAAKISNAMGNRDFLGNIEGFTEKGDTDLSGLKILDEYKFRVILKSP FT NRNFVAKLSYSVFWPLPSDAYKDIRAFGLKPIGNGPYSLVSFTQDVEAVLKKNPDYKGP FT RQPRNSGLRYKIYSDPGPAYADVLSDSSDVTDIIPPNAQEKFQSDFPSRWVRREIAATI FT YIAIPGYVAHFAFDREGILRRKAVSMAINRQDIADKIYHGARVPARDFTSPSVLGYKAG FT LPGSDVLKYDPERAKQLWAQADAISPWGSGVLYLNFAATRGDKALFEALANSIKNVLGI FT EVQAYPNTDWKANLLHGQQTKQPFRIGWAADWPAIDTYLGSLFHSQASNNYYEFRNAEY FT DSLLVKAAEALTFPKAQDYYDKLQEILFQNMPVVPLFYDRGGLVWSKNVSNVESNWVGV FT PVYYLITKG" FT misc_feature 158391..158489 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.577 between residues 33 and 34" FT misc_feature 158409..159963 FT /note="Bacterial extracellular solute-binding proteins, FT family 5 Score = 96.8 E-value = 3e-26" FT misc_feature 158427..158459 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS 159968..161569 FT /transl_table=11 FT /locus_tag="TW146" FT /product="putative ABC transporter substrate-binding FT protein" FT /note="Similar to Streptomyces coelicolor putative peptide FT transport system secreted peptide-binding protein SCO5117 FT or SC9E12.02 SWALL:Q9F353 (EMBL:AL391751) (544 aa) fasta FT scores: E(): 3.3e-48, 33.39% id in 512 aa" FT /db_xref="GOA:Q83NT0" FT /db_xref="HSSP:1B52" FT /db_xref="InterPro:IPR000914" FT /db_xref="UniProtKB/TrEMBL:Q83NT0" FT /protein_id="CAD66826.1" FT /translation="MKYMNSRFKFFAAFIPVVLFMAACFGGSPGVKGKEMRFGSCEPQT FT ALLPGSVRDECGSGIVTNLFVGLVTRDREGNLINEVAESIETQDNLTYVIKVKKDWKFS FT NGEKVTAKSFVDAWNFTAKKSNAQSNRDDLKYIDGYSADLDGDLSGLKITDEFTFTVKL FT NKKLNDFSERLSNTTAFFPLPSVAYQDIKKFGQNPIGNGPYLLHDRRKNVSWSYRPNRD FT YHGYASQFPIPPSVRVTVYQSGSAKYADYLAGNLDLVDVPQENIETYKQDSEGRHIEGV FT TSVVSYIGITANTPGFELNTEAGKLRRRALSLAIDRQEMGDKLYHGLRFPATGFFSSAF FT FPNYADLPGSDVLKFNLEKAKEFWAEAEKLSPYPRRQIDFFYNVDGGHKIWIDAVVNQL FT KNGLGITNIIPKPVPTFREFLDLVDQDDFSGFFRSGWQTGYIAAPSIETLFTSDGSNNS FT SRYRNPEFDKLAVRAVEAKTSESASLYKELLGILLKDLPLIPLFGYKDALVYGKDVKGI FT KLNKRGIVDTSDMIRE" FT misc_feature 159968..160066 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.787 between residues 33 and 34" FT misc_feature 159986..160054 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29" FT misc_feature 160004..161561 FT /note="Bacterial extracellular solute-binding proteins, FT family 5 Score = 94.3 E-value = 1.7e-25" FT misc_feature 160007..160039 FT /note="PS00013 Prokaryotic membrane lipoprotein lipid FT attachment site." FT CDS complement(161570..162175) FT /transl_table=11 FT /locus_tag="TW147" FT /product="putative ABC transporter integral membrane FT subunit" FT /note="Similar to Rhizobium meliloti hypothetical FT transmembrane protein smc00963 r00889 or smc00963 FT SWALL:Q92RI2 (EMBL:AL591785) (201 aa) fasta scores: E(): FT 2.3e-12, 34.23% id in 184 aa" FT /db_xref="GOA:Q83NS9" FT /db_xref="InterPro:IPR003339" FT /db_xref="UniProtKB/TrEMBL:Q83NS9" FT /protein_id="CAD66827.1" FT /translation="MKVGVKVKEYNKDGQKYVGRRIPKTPVAVKLLGLAVYGVLMYNIS FT GVYLLLLFLPSLLFFLRVSVAFIKQLIILVGIVSLVNLVFSGAEYAAYSALRMSALLAG FT AYTVSRTTRFSEFLNFFIIVATPLRIFGLNQKRVGLTLSMTVRFVPEILTLHTQVREAQ FT IARGVQKKPLAIFLPFTVLSLNMAQEIATAIASRGFED" FT misc_feature complement(order(161777..161836,161897..161965, FT 161993..162061)) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 39-61, 71-93 and 114-133" FT CDS complement(162302..162985) FT /transl_table=11 FT /locus_tag="TW148" FT /product="putative ABC transporter ATP-binding subunit" FT /note="Similar to Deinococcus radiodurans ABC transporter, FT ATP-binding protein dr2469 SWALL:Q9RRL9 (EMBL:AE002076) FT (226 aa) fasta scores: E(): 3.2e-27, 42.98% id in 221 aa" FT /db_xref="GOA:Q83IA6" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83IA6" FT /protein_id="CAD66828.1" FT /translation="MIAIEFSNVSLEIDDCKILREINLVFSAHRIGIIGVNGSGKSTLV FT RLINGLHFPSNGCVKVDGIEVNKKTVKQIRRMVGFVFQNPQTQLVMPEVREDLKFGLKN FT MGIQNIESAIEEVSVMLGIQNLLGRNTYQLSGGEKQMVALATILVTKPKVLVFDEPTTY FT LDLMSFNRLSEIVNTLPQQIITISHNLDLIQTCNQVILMNQGQVAYDGPPKNAIAKYRE FT LCKSA" FT misc_feature complement(162373..162904) FT /note="ABC transporter Score = 169.5 E-value = 3.9e-48" FT misc_feature complement(162542..162586) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(162860..162883) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 163138..164073 FT /transl_table=11 FT /locus_tag="TW149" FT /product="putative ABC transporter integral membrane FT subunit" FT /note="Similar to Streptomyces coelicolor putative peptide FT transport system integral membrane protein SCO5118 or FT SC9E12.03 SWALL:Q9F352 (EMBL:AL391751) (307 aa) fasta FT scores: E(): 6.3e-45, 42.15% id in 306 aa, and to Bacillus FT subtilis oligopeptide transport system permease protein FT OppB SWALL:OPPB_BACSU (SWALL:P24138) (311 aa) fasta scores: FT E(): 2.4e-28, 34.07% id in 314 aa" FT /db_xref="GOA:Q83NS8" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q83NS8" FT /protein_id="CAD66829.1" FT /translation="MGRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPS FT PDVVAAIREQYNLDKPFIVQYFIWFSGILTGNMGVTFSGQSVTEVLGSTIPVSAQLGFM FT ALVIQLLLGLSVGLIAGLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLRLLP FT VTVGGDTSFYRMLLPAFSLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIF FT GHIVRNSLLVVVTLIGFDLAGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSA FT VFVIAFMLANLLVDISYSYIDPRIRLSGRK" FT misc_feature 163138..163251 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.824) with cleavage FT site probability 0.215 between residues 38 and 39" FT misc_feature order(163165..163233,163324..163392,163435..163503, FT 163540..163608,163651..163719,163822..163890, FT 163972..164040) FT /note="7 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 10-32, 63-85, 100-122, FT 135-157, 172-194, 229-251 and 279-301" FT misc_feature 163729..163942 FT /note="Binding-protein-dependent transport systems inner FT membrane component Score = 40.2 E-value = 3.3e-09" FT CDS 164075..165040 FT /transl_table=11 FT /locus_tag="TW150" FT /product="putative ABC transporter system integral membrane FT subunit" FT /note="Similar to Corynebacterium glutamicum ABC-type FT transporter, permease components cgl1992 SWALL:BAB99385 FT (EMBL:AP005280) (333 aa) fasta scores: E(): 2.3e-50, 45.77% FT id in 308 aa, and to Bacillus subtilis oligopeptide FT transport system permease protein OppC or Spo0KC FT SWALL:OPPC_BACSU (SWALL:P24139) (305 aa) fasta scores: E(): FT 6.1e-29, 31.77% id in 299 aa" FT /db_xref="GOA:Q83NS7" FT /db_xref="InterPro:IPR000515" FT /db_xref="UniProtKB/TrEMBL:Q83NS7" FT /protein_id="CAD66830.1" FT /translation="MSNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIW FT VYLRRRFAFWFSVVVLFTLTLAALFPGLFTRVPPNSDCYLKNSNGGPTGEHILGFTKQG FT CDVFSRIVHGASTSLSVGLLTLAFALAIGVTIGALAGFFGGWVDAIISRAADIFFVIPF FT LVAAIVVMSAFSSFRSVFTIALVLAVFGWPGTARLVRSEVYRVKNLEFVLAAHCLGQRK FT WGILMKHIIPNSLSPIYSLAAISVGYAIISETVLSFLGLGLPSNVMSWGNDIASAQPDL FT RNNPMTLFWPSLVLSVTVLAFTLLGDVIRKANNPAERSKG" FT misc_feature order(164228..164296,164435..164503,164522..164590, FT 164603..164671,164762..164830,164933..165001) FT /note="6 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 52-74, 121-143, 150-172, FT 177-199, 230-252 and 287-309" FT misc_feature 164681..164909 FT /note="Binding-protein-dependent transport systems inner FT membrane component Score = 20.6 E-value = 0.00061" FT CDS 165037..166665 FT /transl_table=11 FT /locus_tag="TW151" FT /product="putative ABC transporter ATP-binding subunit" FT /note="Similar to Mycobacterium tuberculosis putative FT peptide ABC transporter ATP-binding protein Rv3663c or FT mtv025.011c or mt3764 SWALL:O69631 (EMBL:AL022121) (548 aa) FT fasta scores: E(): 2e-88, 52.67% id in 543 aa" FT /db_xref="GOA:Q83IA5" FT /db_xref="HSSP:1B0U" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83IA5" FT /protein_id="CAD66831.1" FT /translation="MNTVEPPLLDVRNLQIEFSTPTRAIKAVDGVSFTLEKGDTLAIVG FT ESGSGKSTLAHSVIGLLPGTGRITEGQINYAGRDLVKLSQKQLEGVRGHNIGFVPQDPM FT QSLNPVLRIGAQVEEAIRANALASDNKEIRKLAIQALENAGLPNPSDRIRSYPHQLSGG FT MQQRVLIGIALSCHPGLLIADEPTSALDVTVQKVILDHIAERTSSLGTAVMLITHDLAL FT AAERARRLLVMYKGKVVELGSSEEILKNPRHPYTKKLLGAAARARRSPLRSKEQDTAPP FT AVVVDSLVKRYPIRSGTFSTSLLTAVDGVSFSIPSGSTVALVGESGSGKSTIAKIILGF FT EKPTRGTVTIAGVNTSSLSASGLRRMAARIQPVFQNPYGSLDPLRNIASIISEPLSIHK FT VGNRASRKARVVELLDQVALPQFIATRYPGELSGGQRQRVAIARALALKPEIMILDEAV FT SALDALVQSQILDLLDSLQKQLSVSYLFITHDLAVARAISDFVCVMHQGKLVEQGPAER FT IFNNPESKYTRTLLESIPGRLFSWG" FT misc_feature 165148..165742 FT /note="ABC transporter Score = 178.0 E-value = 1.1e-50" FT misc_feature 165169..165192 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 165514..165558 FT /note="PS00211 ABC transporters family signature." FT misc_feature 165985..166555 FT /note="ABC transporter Score = 191.4 E-value = 1e-54" FT misc_feature 166006..166029 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 166327..166371 FT /note="PS00211 ABC transporters family signature." FT repeat_region 166803..171844 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS complement(171897..172667) FT /transl_table=11 FT /locus_tag="TW152" FT /product="putative membrane protein" FT /note="Doubtful CDS. No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NS6" FT /protein_id="CAD66832.1" FT /translation="MNRPIKTIRSRQCLVIFFFTLCLSVMFVILSLIATEWQYALLALI FT LCVCSCLPFYVLFASPKLEVHQEYLRVVGPVRELRLPFDDIEEVLAAPMLTLKLKSGKV FT ISCWGIIKRGRLLESEIQEARLSGEWSEIIPVSQSGQTYSSEIHPNLRAGTIRLDDEKE FT REKGQYGGGHECNKHNAPEKDPLQKNPLQLSISHSEIPRGCTSAISSPEVGTEMGAEID FT TRLISRSYNTLNIALLIVSCSLLFVSYFTLYYFQ" FT misc_feature complement(order(171903..171971,172485..172553, FT 172563..172631)) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 13-35, 39-61 and 233-255" FT misc_feature complement(172560..172667) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.707 between residues 36 and 37" FT repeat_region 172696..178092 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT repeat_region 173678..173741 FT /note="(ggcgagaaatatgtat)4" FT CDS 178288..178713 FT /transl_table=11 FT /gene="rplM" FT /locus_tag="TW153" FT /product="50S ribosomal protein L13" FT /note="Similar to Escherichia coli 50s ribosomal protein FT L13 RplM or b3231 or z4589 or ecs4104 or stm3345 or sty3525 FT SWALL:RL13_ECOLI (SWALL:P02410) (142 aa) fasta scores: E(): FT 3.8e-25, 54.33% id in 127 aa, and to Streptomyces FT coelicolor 50s ribosomal protein L13 RplM or SCO4734 or FT SC6G4.12 SWALL:RL13_STRCO (SWALL:Q53874) (147 aa) fasta FT scores: E(): 3e-29, 52.94% id in 136 aa. N-terminus FT truncated relative to homologues." FT /db_xref="GOA:Q83IA4" FT /db_xref="InterPro:IPR005823" FT /db_xref="UniProtKB/TrEMBL:Q83IA4" FT /protein_id="CAD66833.1" FT /translation="MSSKQWVLVDAKDMVLGRLATQVAVLLRGKHRPTYEPHLDTGDCV FT IVVNAALIRVTSNKHAKKVFYTHSGYPGGLKKRGFSDVFQKSPERVLEKAVKGMLPKNK FT LGRSVFRNLRVYPGQDHPHAAQKPSVYAPTRVAQVLV" FT misc_feature 178303..178684 FT /note="Ribosomal protein L13 Score = 225.7 E-value = FT 4.9e-65" FT misc_feature 178573..178641 FT /note="PS00783 Ribosomal protein L13 signature." FT CDS 178713..179177 FT /transl_table=11 FT /gene="rpsI" FT /locus_tag="TW154" FT /product="30s ribosomal protein S9" FT /note="Similar to Escherichia coli 30s ribosomal protein S9 FT RpsI or b3230 or z4588 or ecs4103 SWALL:RS9_ECOLI FT (SWALL:P02363) (129 aa) fasta scores: E(): 2.6e-20, 51.61% FT id in 124 aa, and to Streptomyces coelicolor 30s ribosomal FT protein S9 RpsI or SCO4735 or SC6G4.13 SWALL:RS9_STRCO FT (SWALL:Q53875) (170 aa) fasta scores: E(): 2.4e-25, 61.6% FT id in 125 aa" FT /db_xref="GOA:Q83IA3" FT /db_xref="InterPro:IPR000754" FT /db_xref="UniProtKB/Swiss-Prot:Q83IA3" FT /protein_id="CAD66834.1" FT /translation="MVPPQRAKNDTSSAPDSAAETRGPLVSSGSGLGRRKSATARVYLS FT PGEGVFVVNGRDINEYFTSKLHRQFACQPLKILDLLGSYDVKVTLHGGGASGQAGAVRL FT GIARALNTIDPENNRKPLKSAGFLTRDSRVKERKKAGLKKARKAPQYSKR" FT misc_feature 178809..179172 FT /note="Ribosomal protein S9/S16 Score = 192.8 E-value = FT 3.7e-55" FT misc_feature 178986..179042 FT /note="PS00360 Ribosomal protein S9 signature." FT CDS 179181..180542 FT /transl_table=11 FT /locus_tag="TW155" FT /product="putative phospho-sugar mutase" FT /note="Similar to Streptomyces coelicolor putative FT phospho-sugar mutase SCO4736 or sc6g4.14 SWALL:Q53876 FT (EMBL:AL031317) (452 aa) fasta scores: E(): 3.6e-76, 50% id FT in 458 aa" FT /db_xref="GOA:Q83NS5" FT /db_xref="InterPro:IPR006352" FT /db_xref="UniProtKB/Swiss-Prot:Q83NS5" FT /protein_id="CAD66835.1" FT /translation="MARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQ FT VLGKRPVAIVARDPRISGDFLVAAISAGLASSGVDVLDAGVIPTPAVAFLVKNANADFG FT FMISASHNPGYDNGVKIFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFVDAE FT DRYQMHLLSTLFTRIDGVKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDG FT VGSAYPERLRAEVIRNSATLGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGT FT LRNKTLVTTIMSNIGLDRAMKKLGINLKRTQVGDRYVIEAMTQGGFNIGGEQSGHIILS FT DYSTAGDGILAGLHLCAEIIRTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRH FT EISRIEKSLKGRVVIRPSGTEPLIRIMVEDLNPEKAERACSHLADFFKQEIQKS" FT misc_feature 179181..179634 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain I Score = 155.2 E-value = 7.9e-44" FT misc_feature 179670..179964 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain II Score = 80.7 E-value = 2.2e-21" FT misc_feature 179970..180306 FT /note="Phosphoglucomutase/phosphomannomutase, FT alpha/beta/alpha domain III Score = 86.9 E-value = 3e-23" FT misc_feature 180330..180522 FT /note="Phosphoglucomutase/phosphomannomutase, C-terminal FT domain Score = 17.6 E-value = 0.00048" FT CDS complement(180517..181272) FT /transl_table=11 FT /gene="coaA" FT /locus_tag="TW156" FT /product="pantothenate kinase" FT /EC_number="2.7.1.33" FT /note="Similar to Escherichia coli pantothenate kinase CoaA FT or Rts or PanK or b3974 or z5545 or ecs4901 FT SWALL:COAA_ECOLI (SWALL:P15044) (316 aa) fasta scores: E(): FT 4.5e-12, 39.66% id in 242 aa" FT /db_xref="GOA:Q83IA2" FT /db_xref="HSSP:1ESM" FT /db_xref="InterPro:IPR004566" FT /db_xref="UniProtKB/TrEMBL:Q83IA2" FT /protein_id="CAD66836.1" FT /translation="MGIEVFKKDITKTYTEMLKDIRKRVRERGKVGKSFIIGITGSVAA FT GKSTLASDLAKMLDGISVEVISTDGYLYPNKILEQKGLMLKKGFPESYDTAHLASLVKN FT IKAGAKTIGIRQYAHPIHDVTGVIKTVNKPEILIIEGLNVMRHPVKTVVDLGIYIEAPK FT RSVFKWYVKRFFELRAQHEKNTYFRKYANLPRRQCIKMLKQVWRDVNRKNFTENILPVK FT HTADFIVYKNPRHKMTLYRNEASSSGFPV" FT misc_feature complement(181129..181152) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 181825..181959 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.891 between residues 45 and 46" FT CDS 181855..183954 FT /transl_table=11 FT /locus_tag="TW157" FT /product="WiSP family protein" FT /note="No significant database matches. Has possible FT N-terminal secretion signal sequence and 3 possible FT membrane spanning regions in the C-terminal portion. FT Similar to CDS TW161 - TW157 residues 8-275 identical to FT TW161 residues 7-274, though not similar at sequence level FT TW161 C-terminal portion also contains 3 possible membrane FT spanning regions. Region following identity with TW161 is FT an array of small repeats." FT /db_xref="InterPro:IPR012503" FT /db_xref="UniProtKB/TrEMBL:Q83NS4" FT /protein_id="CAD66837.1" FT /translation="MKKQYRHPLSYLTKAFTLLLTLLLLSSLQYETAFARQTPPALSLL FT SSVSSTSVSSNTKYTRVSNTNTQEVCVTTNTNVSLLIDPVTSSTKQTLSCTPSLSPQPQ FT THIYVPYTDTSSYLYVPYITNTHISLYYTDKKADPSSFLTFPHTDIATPYGDEKVVSIT FT KTTTNLIALLTTRNIFFFDIHVTEKPKITVPIHKQIDNTYLSDIPSLRNSRYTFSLTHP FT NKDITIDRYTGQIHLSSLPTSPITAIAINKDTSTHITYAIDTHNPTTHNRSKRAAPRQS FT SGYSWGDLFGNITSAAAGAITSALSGLANSFLGSSTTPSLSSTATGVSIGQSTITITPN FT ARGSPTSYIATPTGATSGGANAAGLPKGLTLNSSGTITGSIDTGVSQGIYTVVVTATAS FT KTSIVSATYTLLVTSTTPSLSGTTITIYTTTPVSLSVTGFITGYAINPTTPTDTSSQKT FT HTVTINIDKTNGNITITPSIVPGTYTVTITATAPSYTSSATTLTSTIVIAVYTLVLSSM FT KFFQRVKYYITKPFKAIYSWFSHTCTPVHHTTSQGFLGAATALLPAAVTSLVDAYNAFY FT SAAHNSDACYDWKSYAYPVASLYGQVGIKALYRKISAHLPSFSGWGGKFFRAFMSAVSV FT GAVYFLPFYLYGKLVKKPASSSGSGSNSNNSSLSGIIRNYFTGNWRTLLPGLFAPALTL FT LTLWF" FT repeat_region 181874..182680 FT /note="Repeated directly at 193785..194591. Codes for the FT sub-N-terminus of a possible surface protein" FT misc_feature order(181885..181953,183334..183402,183508..183576, FT 183727..183795) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 21-43, 504-526, 562-584 and FT 635-657" FT repeat_region 182423..183559 FT /note="Coding degenerate repeat region in Repeat Cluster 1 FT (RC1). Related to local non-coding repeat regions." FT variation 182819 FT /note="polymorphic base C or A" FT variation 182821 FT /note="polymorphic base: A or G" FT variation 182823 FT /note="polymorphic base: T or C" FT CDS 184178..186028 FT /transl_table=11 FT /gene="glmS" FT /locus_tag="TW158" FT /product="glucosamine--fructose-6-phosphate FT aminotransferase [isomerizing]" FT /EC_number="2.6.1.16" FT /note="Similar to Escherichia coli FT glucosamine--fructose-6-phosphate aminotransferase FT [isomerizing] GlmS or b3729 SWALL:GLMS_ECOLI (SWALL:P17169) FT (608 aa) fasta scores: E(): 9.8e-90, 42.23% id in 618 aa, FT and to Streptomyces coelicolor FT glucosamine--fructose-6-phosphate aminotransferase FT [isomerizing] GlmS or SCO4740 or SC6G4.18 SWALL:GLMS_STRCO FT (SWALL:O86781) (614 aa) fasta scores: E(): 1.5e-125, 53.73% FT id in 616 aa" FT /db_xref="GOA:Q83IA1" FT /db_xref="HSSP:1GDO" FT /db_xref="InterPro:IPR001347" FT /db_xref="UniProtKB/Swiss-Prot:Q83IA1" FT /protein_id="CAD66838.1" FT /translation="MCGIIGYSGPRPAAEVLLKGLERLEYRGYDSAGIAVVTDKAYIES FT VKKSGKLNVLKTCLERRTTPIVGSTGIGHTRWATHGEPSDRNAHPHMDTEQSLAIVHNG FT IIENSDVLKRELLASGKSFTSETDTEVVAHLLSDAFKKTQDLVQAFVEVTQRLEGAFAV FT VAIHKDQPNTIVAAKNNSPLLLGFGQGENFLASDIAAFAEYTQRVANIDQERIVALSGD FT SVYITDFAGHPVDYEVHTVSWHPASVDSSGWSSFMLKEIFEEPQAVENTLKGRTEDGTV FT ILPECDHIRDDLLAIDRVVLVGCGTAAYAAMTASYSIEAWAGLPVSVELSHEFRYREPV FT LNSKTLAVFISQSGETMDSLMAVRYARQAGVKTISVCNVMDSSIPKESHAVIYTKAGPE FT VAVASTKSFVCQIVVLYLLALYLGQLRGFRSIFPRQKAVCELNRLPVKLKQVLEIYESV FT RQLAHWMSDSRSILFLGRHAGYPIALEAALKLKELAYIHAEGFAAGELKHGPIALIEPG FT QPVFVIVPSPVGSPILHAKVISNIREIKSRGARIIAIAAEGDSAVLPHADSVLRIPLTR FT YSFEPLLSIVPLQIFALELAADKGFDVDRPRNLAKSVTVE" FT misc_feature 184178..184195 FT /note="PS00443 Glutamine amidotransferases class-II active FT site." FT misc_feature 184181..184733 FT /note="Glutamine amidotransferases class-II Score = 221.0 FT E-value = 1.2e-63" FT misc_feature 185045..185447 FT /note="SIS domain Score = 136.8 E-value = 2.7e-38" FT misc_feature 185054..185083 FT /note="PS00339 Aminoacyl-transfer RNA synthetases class-II FT signature 2." FT misc_feature 185561..185981 FT /note="SIS domain Score = 119.4 E-value = 4.6e-33" FT repeat_region 185973..187677 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT tRNA complement(187804..187874) FT /note="tRNA Gln anticodon TTG, Cove score 59.16" FT CDS complement(187878..189107) FT /transl_table=11 FT /gene="ispE" FT /locus_tag="TW159" FT /product="4-diphosphocytidyl-2-c-methyl-D-erythritol FT kinase" FT /EC_number="2.7.1.148" FT /note="Similar to Escherichia coli FT 4-diphosphocytidyl-2-c-methyl-D-erythritol kinase IspE or FT Ipk or b1208 or z1979 or ecs1713 SWALL:ISPE_ECOLI FT (SWALL:P24209) (283 aa) fasta scores: E(): 7.7e-07, 28.95% FT id in 221 aa, and to Streptomyces coelicolor FT 4-diphosphocytidyl-2-c-methyl-D-erythritol kinase IspE or FT SCO3148 or SCE66.27c SWALL:ISPE_STRCO (SWALL:Q9K3R6) (299 FT aa) fasta scores: E(): 5.9e-21, 39.07% id in 238 aa. Note FT possible alternative translational start sites." FT /db_xref="GOA:Q83IA0" FT /db_xref="InterPro:IPR014721" FT /db_xref="UniProtKB/Swiss-Prot:Q83IA0" FT /protein_id="CAD66839.1" FT /translation="MKTDGGNTWRASHSKPLNTANTMGEPFSHSEYSVHADQSEFYLNE FT LTEHSGQDNPCMNTSRLNTNRYGHPVVHPCPKIHCICTQSNIAAIGSDCTGCVDIAQAC FT KMLRGGQGCTQDPCVKNPHTQCFTDVSNHAMRNVLPLNVSNTEQFPIQIEYANGRNPVL FT NPMDDLAMRAALLLSKDIDLQNTHILPSTRISIEKNIPVAAGLAGGSADAAAVLLGINS FT AWQTNYSRCDLLGKAGALGADVPFLIWGGAAYGSGTGSCVTFFETQTLYWVLCFSKHPL FT STRKVFQELDRQRSGAGCNHHPVFSNPAECAEMLKKAIKRGPEALAALLHNDLTSAAKM FT LMPEIAERIKAAERCPGILRAIISGSGPTLALLAEDAEAANRACSILKDTGVICKAVSS FT PAYSSIYWQT" FT misc_feature complement(187898..189266) FT /note="GHMP kinases putative ATP-binding protein Score = FT 49.3 E-value = 6e-12" FT repeat_region 189310..191014 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS 191188..192282 FT /transl_table=11 FT /locus_tag="TW160" FT /product="putative membrane protein" FT /note="Similar to Corynebacterium glutamicum FT uncharacterized membrane proteins cgl2282 SWALL:BAB99675 FT (EMBL:AP005281) (264 aa) fasta scores: E(): 2.1e-24, 43.16% FT id in 278 aa" FT /db_xref="GOA:Q83NS3" FT /db_xref="InterPro:IPR008217" FT /db_xref="UniProtKB/TrEMBL:Q83NS3" FT /protein_id="CAD66840.1" FT /translation="MKDNHDRERKKWRRYLRREITEARIYEILATRFKQKQIFLDLAKA FT EKRHAQHWRNLLGNEPDPKPKDFLLRLMAKYGSKVIVLSFLQRAEAKAPYFRDVNAVHM FT AADETIHKEVIRAVAAPNRQSISGPFRAAVFGINDGLVSNTALIVTMAVFTDNITLLLL FT TGFGGLLSGSLSMAAGEYVSVTSQKELINSNTPDPESYKALSNLSIDANELSLVYRARG FT MTPAQAQHRANRVLEIVRHTDNLRLHVPDPITSNLNQHHSNTTGLPNDHNQALGNPWTA FT AITSFILFATGALIPLLPFLIPIPIHLALPTSLTLFTLCLLITGAVIALLSGSNIIVKA FT LRQLIIGALATILTSILTLFFGHH" FT misc_feature order(191584..191652,191665..191733,192031..192099, FT 192112..192180,192217..192276) FT /note="5 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 133-155, 160-182, 282-304, FT 309-331 and 344-363" FT repeat_region 192292..192718 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT tRNA complement(193050..193125) FT /note="tRNA Phe anticodon GAA, Cove score 74.74" FT tRNA complement(193131..193204) FT /note="tRNA Asp anticodon GTC, Cove score 87.26" FT tRNA complement(193214..193289) FT /note="tRNA Glu anticodon TTC, Cove score 54.89" FT repeat_region 193286..193640 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT misc_feature 193745..193870 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.999) with cleavage FT site probability 0.819 between residues 42 and 43" FT CDS 193769..196159 FT /transl_table=11 FT /locus_tag="TW161" FT /product="WiSP family protein" FT /note="No significant database matches. Has possible FT N-terminal secretion signal sequence and 3 possible FT membrane spanning regions in the C-terminal portion. FT Similar to CDS TW157 - TW161 residues 7-274 identical to FT TW157 residues 8-275, though not similar at sequence level FT TW157 C-terminal portion also contains 3 possible membrane FT spanning regions." FT /db_xref="InterPro:IPR012503" FT /db_xref="UniProtKB/TrEMBL:Q83NS2" FT /protein_id="CAD66841.1" FT /translation="MPTSPNPLSYLTKAFTLLLTLLLLSSLQYETAFARQTPPALSLLS FT SVSSTSVSSNTKYTRVSNTNTQEVCVTTNTNVSLLIDPVTSSTKQTLSCTPSLSPQPQT FT HIYVPYTDTSSYLYVPYITNTHISLYYTDKKADPSSFLTFPHTDIATPYGDEKVVSITK FT TTTNLIALLTTRNIFFFDIHVTEKPKITVPIHKQIDNTYLSDIPSLRNSRYTFSLTHPN FT KDITIDRYTGQIHLSSLPTSPITAIAINKDTSTHITYAIDTHNPTTHNRSKREMQDRQI FT KNPHVNRSPLKVQDRALINTSLDKWCSELTICNGGNEPIIRYYGYLMLTPNISNITTTV FT SVNQSTITISPSWSIPGKIIRTSTDSHGWLHGTGFAKSYATPTSFLINTSNVITNGMNS FT MFSLPSGLTLNTSNGEITGSIDKSVTPGLYQFVVTAFFGKTLSYVNPFFGKNWTYTFTL FT SDSYTTATYQIYVTYRESNSLYITLIQGQNLSLTAPFPSRYAMTLLHTAGSLPSGLNLV FT SRSITGIVAGPPGVYEYVVTYARTATIGQYSKHGTSSTNVFLKGICNTCSRKTAIFEHM FT PKDVYTTLSTVITPELAVVTYIFTVLGQLKTNTVHTYASLGAKRVSISLPVPPFFLLFS FT QYTYTTLTSPGSGLPKGLTLDRYRKYITGSINPSITQGVYIAYITALAVFTIAVDAVYI FT TVYNTDISTTSIKTSVLIGQSSVYIPLPSSSFYTLSVTETDRTEPGVGLPSGLFIDTAV FT GVVRGQVNRNVRPGLYTVNISLDVFKIRKKDTLFIYVLPYTPL" FT repeat_region 193785..194591 FT /note="Repeated directly at 181874..182680. Codes for the FT sub-N-terminus of a possible surface protein" FT misc_feature order(195506..195574,195629..195697,195791..195859) FT /note="3 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 588-610, 629-651 and 683-705" FT repeat_region 196197..197688 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS complement(197697..199415) FT /transl_table=11 FT /locus_tag="TW162" FT /product="putative ABC transporter (ATP-binding and FT integral membrane)" FT /note="Similar to Escherichia coli transport ATP-binding FT protein CydC or MdrA or MdrH or SurB or b0886 FT SWALL:CYDC_ECOLI (SWALL:P23886) (573 aa) fasta scores: E(): FT 4.8e-32, 27.92% id in 573 aa" FT /db_xref="GOA:Q83I99" FT /db_xref="HSSP:1MT0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83I99" FT /protein_id="CAD66842.1" FT /translation="MLKDLLILAGKLRKCLGLFTLATLVLIIWNLAETGIAVVSLFISS FT AFFSDTQAELQGLFILLFSLVVVYPVFNLLDIWLAHDVANRILHILRVSTYSAINRIAP FT LGLQNKRTADIASAALSDTSELEWFYTQILPSAIFTIVNSIIFTTILTWLIGPIGLFMI FT IPMILTIIFPFVLVPIQRRQGVASRETLVDLRAAVLNAVQGQRELRSLGMVKKQHEVVI FT AATERVQKIKNAHNLRKALELAFSSLVTAAGSIILLIILTDRVLNGQLDGRILPVAILL FT AGLSVIPSYILADAMGRMGDFGACAMRINKILKAKDPIPTEPRRGLEKHHNEDNTLVAD FT DIGFSYDSQPVLSGVNLTVSPSRSVAIVGHSGAGKSTLANLAMRFLDPDDGEMRFDGLN FT LHGYNPDVYRQRLSLVPQDCHIFAGTIRQNLELAKDGVSDDAIWEALKLADIATLVESL FT GGLDAPVGDRGTTLSGGERQRIGIARAFLRNPDMLILDEPLANIDPLLEANIAANVRRL FT RGGRTTIVIAHRLASIRIADHIIVLDNGGVVAQGTHKKLLNNMHYLELLGNQIQQ" FT misc_feature complement(197783..198332) FT /note="ABC transporter Score = 201.4 E-value = 9.6e-58" FT misc_feature complement(197958..198002) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(198288..198311) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(order(198537..198602,198630..198698, FT 198879..198938,198951..199019,199176..199244, FT 199287..199355)) FT /note="6 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 21-43, 58-80, 133-155, FT 160-179, 240-262 and 272-293" FT misc_feature complement(198551..199361) FT /note="ABC transporter transmembrane region Score = -19.6 FT E-value = 0.0025" FT misc_feature complement(199269..199415) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.981) with cleavage FT site probability 0.595 between residues 49 and 50" FT CDS complement(199447..201318) FT /transl_table=11 FT /locus_tag="TW163" FT /product="putative ABC transporter (ATP-binding and FT integral membrane)" FT /note="Similar to Clostridium perfringens probable ABC FT transporter cpe0226 SWALL:Q8XNV6 (EMBL:AP003185) (576 aa) FT fasta scores: E(): 2.7e-35, 26.56% id in 576 aa" FT /db_xref="GOA:Q83I98" FT /db_xref="HSSP:1PF4" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83I98" FT /protein_id="CAD66843.1" FT /translation="MEPISFLTRLLVRLRVCYGKRPPNSRLDLLGSNYRSCDSLVLSEK FT LRVMRAGKITIRLLLPPVLMNLLSFGAYIIAGVFNALLFTELLSQRRLFEITILIGGIA FT LTLIARPLISVGEAVLETRAGTRVKQNLRQALLTELDRRGPMRVGFWRSGKIQALISDG FT IESIDLYFVKYFVHFITTVVSGIVIVIIIWQINWIIAVVLLFCAIGMVGIPRLWDKALG FT KKGQEHWVAYENMNADFIDAMMGMSTLKSFGAAERYGKKLEEQSNRLLSSTRRRLRISL FT GENGLRSLMRALGPALGLVIAIFQIRAGHMEIGQLFLVIMLSIELFRPLNTLVILYYGA FT FFGIAAVSSINEILEERSHSVAHNNHETPSLTGLTGFDRVSYTYIGADKSALTHTTFSI FT PSNKTTAIVGLSGSGKSTALGLLMGFDRPNSGQIRVFGNDPVSIDTTKVMTLVPQDPVI FT FPGTIREILASANRKATEAEMIEALRYAQETTLHLETEHDELDILDVCIFEHGKNLSGG FT QKQRLAIARALIRNTPILVLDESTSALDTMTESALLKAIRTARPDLTLLIVTHRIDTAA FT KADQVVVMANGSVTCAGAPQLLARDKDSVWSKLVKAQLGDVNVERIE" FT misc_feature complement(199560..200115) FT /note="ABC transporter Score = 156.8 E-value = 2.6e-44" FT misc_feature complement(199735..199779) FT /note="PS00211 ABC transporters family signature." FT misc_feature complement(200071..200094) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(order(200275..200343,200401..200469, FT 200668..200736,200746..200814,200959..201027, FT 201085..201153)) FT /note="6 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 56-78, 98-120, 169-191, FT 195-217, 284-306 and 326-348" FT misc_feature complement(200331..201147) FT /note="ABC transporter transmembrane region Score = 37.9 FT E-value = 1.7e-08" FT repeat_region 201593..202308 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS complement(202542..203240) FT /transl_table=11 FT /locus_tag="TW164" FT /product="putative integral membrane protein" FT /note="Similar to Streptomyces coelicolor putative integral FT membrane protein SCO2196 or SC5F7.05 or SC3H12.04 FT SWALL:Q9S2P0 (EMBL:AL096872) (234 aa) fasta scores: E(): FT 5.7e-15, 31.89% id in 232 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NS1" FT /protein_id="CAD66844.1" FT /translation="MPKSNKKAPGRIAQIMQVLRIACSGRPKVVVYLIAAGITPLVAGI FT SAAVILAYTSILVFILLILISVGAALLSFMITLGKQAEKVAYSQVEGRPGATGAVIKTF FT RGCWQTSEIPVAVNPKTADAIYRAVGKCGVVLIIEGMRQRAQKMLAEEQRRVKRVLPNI FT QIHVLNVNHLDPKSVPLNRLGKKMRSLKKTLHRSEVWKAGKLLDAIPKNYMPVPKGMDL FT KKPVKRPSRG" FT misc_feature complement(order(203007..203075,203088..203156)) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 29-51 and 56-78" FT misc_feature complement(203085..203240) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.866) with cleavage FT site probability 0.502 between residues 52 and 53" FT CDS 203335..204531 FT /transl_table=11 FT /locus_tag="TW165" FT /product="putative serine/threonine protein kinase" FT /note="Similar to Streptomyces coelicolor putative FT serine/threonine protein kinase SCO1724 or SCI11.13 FT SWALL:Q9S2A6 (EMBL:AL096849) (550 aa) fasta scores: E(): FT 0.0015, 30.3% id in 165 aa, and to Amycolatopsis FT mediterranei serine/threonine kinase PkmA SWALL:Q9KK90 FT (EMBL:AF135382) (589 aa) fasta scores: E(): 0.0043, 25.59% FT id in 168 aa" FT /db_xref="GOA:Q820C1" FT /db_xref="InterPro:IPR000719" FT /db_xref="UniProtKB/TrEMBL:Q820C1" FT /protein_id="CAD66845.1" FT /translation="MIPFFNKHTRSTDDKDTEKARQIIGNYRVIKTLHESDRAVIYLAQ FT EISGDPGMVARQSFMDPGELVNLVALKMYRAGVTSEHIAIEADALDSLRGPGVVELRDV FT LNLPDKRGLVMRALHGPALVDLWETRGSLSPGEMVTILASLVATLARISSAGYAHGAVW FT PGNIRFDDIGRPVLTGFSSARKHAPPNADWLDFYSLLRGCAVLINEKQEQMLQISAGVR FT KRLDPFDPELPAWVEASLFRLADPQPLRFEHPISLHDTSGYNLRESPNPVDSNRQTGKS FT QIILKLTDNKYVAAILGKLKRPSVLFIALFVSVFVVLLMVIPNNSGEDNERKSEKPGYV FT KSKGTFKKPSKTGKSRKRSEVSEKLRKNMEECLASKDADCVDVMSEINADLGEKLDEG" FT misc_feature 204247..204315 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 305-327" FT repeat_region 204575..205214 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS 205328..207172 FT /transl_table=11 FT /locus_tag="TW166" FT /product="putative transcription factor" FT /note="Similar to Caulobacter crescentus elongation factor FT TU family protein cc0741 SWALL:Q9AA65 (EMBL:AE005749) (610 FT aa) fasta scores: E(): 4e-83, 43.18% id in 616 aa, and to FT Streptomyces coelicolor putative GTP-binding protein FT SCO5111 or SCBAC31E11.07 SWALL:Q93IU4 (EMBL:AL596043) (635 FT aa) fasta scores: E(): 8.9e-80, 56.85% id in 635 aa" FT /db_xref="GOA:Q83NS0" FT /db_xref="HSSP:1ELO" FT /db_xref="InterPro:IPR006298" FT /db_xref="UniProtKB/TrEMBL:Q83NS0" FT /protein_id="CAD66846.1" FT /translation="MITKDIRNIAVVAHVDHGKTTLISAMLQQTSDSTTAEDRVLDSHE FT LEREKGITILAKNTAVTYKSSGRSVTLNIVDTPGHADFGGEVERGMSMVDGVVVLVDAS FT EGPLPQTRFVLKKALLKKLPIVLAVNKTDRSDARIDDVVSEFQDLLISLAEEINDPAIY FT SILDVPIVYVSGRAGRASINKPDNGQLPDRNNLDDLFEKIISYIPAPEYDKSAPLQAHV FT ANIDASAFLGRLALTRIYNGSISKGQTVCWVNTSSKQRVNVRVTELLKTVALDRVPVPS FT VSAGDIVAIAGIPDVMIGDSICDPDDVRPLPGISIDEPAISVVIGVNTSPLAGGVPGHK FT LTATQIKERLDRETIGNVSIRVIPTRGTDAWEVQGRGELALAVLIEQMRREGFELTVGK FT PSAVTRIVDGSLHEPYELLTVNLMDEYFGSVTKLLAERKCRVESVISNAGWTNADFVVP FT SRGLIGFRTEFLTITRGTGTANAIFHSYAPWSGQINQRAQGSAVADRAGHVTSYAILGL FT QERVLFFVSPSERVYEGMVVGRNSRPGDLNVNVTKGKKLTNTRSSTAEELEKIVPARHL FT SLEECLEFAGPDECVEVTPEAIRIRKIELSQSVRSKQR" FT misc_feature 205337..205958 FT /note="Elongation factor Tu GTP binding domain Score = FT 223.5 E-value = 2.2e-64" FT misc_feature 205364..205387 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 205451..205498 FT /note="PS00301 GTP-binding elongation factors signature." FT misc_feature 205985..206234 FT /note="Elongation factor Tu domain 2 Score = 48.2 E-value = FT 1.3e-11" FT misc_feature 206555..206816 FT /note="Elongation factor G C-terminus Score = 75.4 E-value FT = 8.5e-20" FT CDS 207488..208330 FT /transl_table=11 FT /locus_tag="TW167" FT /product="conserved hypothetical protein" FT /note="Has C-terminal similarity to proteins of undefined FT function. Similar to Streptococcus pyogenes hypothetical FT protein Spym18_1743 SWALL:AAL98271 (EMBL:AE010084) (153 aa) FT fasta scores: E(): 1.6e-10, 40% id in 140 aa" FT /db_xref="GOA:Q83I97" FT /db_xref="HSSP:1HTW" FT /db_xref="InterPro:IPR003442" FT /db_xref="UniProtKB/TrEMBL:Q83I97" FT /protein_id="CAD66847.1" FT /translation="MRTGVDLVDIIDFKKKIDRSNRLLERLFAPTELSNSYNRKALSVR FT FALKESVIKALGGLAGTWHDIQTSGGTHLPISVSLSGSMLLKADELGLNEWAASVTHSS FT GFAIANVVAQHNTTISHPPWSIQVPTCGATECLGYVLGSVLKPGDVVLLVGELGAGKTT FT FTKGIAAGLGIESAVVSPTFTLVREHVAQNGGMNHVDCYRLIHDFDDFDLDLDNRVTVV FT EWPLSFFWNLPRYLSFKIDFTSKDNTRIFTLHAKGFDIKELAFITHTMSQSHTMSQSQ" FT misc_feature 207491..207815 FT /note="4'-phosphopantetheinyl transferase superfamily Score FT = 48.8 E-value = 8.6e-12" FT misc_feature 207887..208241 FT /note="Uncharacterised P-loop hydrolase UPF0079 Score = FT 111.1 E-value = 1.5e-30" FT misc_feature 207950..207973 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 208351..209856 FT /transl_table=11 FT /locus_tag="TW169" FT /product="conserved hypothetical protein" FT /note="Localised similarity to proteins of unknown FT function. C-terminal similar to Thermoanaerobacter FT tengcongensis acetyltransferases RimI3 or tte0537 FT SWALL:Q8RC99 (EMBL:AE013024) (149 aa) fasta scores: E(): FT 5e-10, 37.24% id in 145 aa. N-termional similar to FT Corynebacterium glutamicum inactive homologs of FT metal-dependent proteases, putative molecular chaperones FT cgl0592 SWALL:BAB97985 (EMBL:AP005275) (225 aa) fasta FT scores: E(): 0.00017, 39.62% id in 106 aa" FT /db_xref="GOA:Q83I96" FT /db_xref="InterPro:IPR016181" FT /db_xref="UniProtKB/TrEMBL:Q83I96" FT /protein_id="CAD66848.1" FT /translation="MKILAIDTSSRLAIACLEIDNNRITTVGKCIEDSGRLHSELIAEA FT ISQACSELQSLSFIAVCLGPGFYTGLRSGLVAARILGLSLSIPVYGVMAHDAIYMGYLS FT CEEHVFCDRGLHTSQVFSHHEPVSKSADGANHEEFCDRNTYSMGDAIHRNVPSIARTII FT TPAGRRQFYWSRYTGLDNDGLPIIYAGPGLIDSCDINILSQDFPFNPVFVASAHEPQFE FT AQKESNGTLTGSPRPRRTGRHIDRGSCPPNVSSTIPPGIFRARVPQAHDCAINVVSKNS FT MRETDTLKTDASIDKSITSDRPNTQPILPVSAVNPVILGKLAYLQLKAKRACSRIEPFY FT MRRADVTLRVPSGEINKDLVSIHPASLHDLPDIMKIERGSFTGEEWSSATMLQQLRLGS FT YFVLKVSDMPVGYAGISHPRFEDVDLETLAIDPAWRRKGLGGILLRHLFEYARDAGVKR FT CFLEVKVCNLPAIGMYKKHGFVTLGRRPKYYNGVDAITMKKEL" FT misc_feature 208456..208624 FT /note="Glycoprotease family Score = 18.0 E-value = 1.9e-05" FT misc_feature 209551..209788 FT /note="Acetyltransferase (GNAT) family Score = 86.8 E-value FT = 3.2e-23" FT CDS 209856..211061 FT /transl_table=11 FT /gene="gcp" FT /locus_tag="TW170" FT /product="O-sialoglycoprotein endopeptidase" FT /EC_number="3.4.24.57" FT /note="Similar to Pasteurella haemolytica FT O-sialoglycoprotein endopeptidase Gcp SWALL:GCP_PASHA FT (SWALL:P36175) (325 aa) fasta scores: E(): 1.5e-13, 36.97% FT id in 384 aa, and to Streptomyces coelicolor probable FT O-sialoglycoprotein endopeptidase Gcp or SCO4752 or FT SC6G4.30 SWALL:GCP_STRCO (SWALL:O86793) (374 aa) fasta FT scores: E(): 4.3e-20, 43.71% id in 398 aa" FT /db_xref="GOA:Q83I95" FT /db_xref="InterPro:IPR000905" FT /db_xref="UniProtKB/Swiss-Prot:Q83I95" FT /protein_id="CAD66849.1" FT /translation="MSIILGIETSCDETGVGIVSGSTVLANEVASSSLRHKPFGGVIPE FT IAARAHLEYLPNLLELALETAQLCIKDIDGIAVTAGPGLVTSLSVGVSAAKALGLSTGT FT PVYGVNHLVGHAVSAFLDDYTNDGLGVIHRRDSIGSNGIENDASSTHSHTHTTQVNRHS FT NLCVYTPPRRVLRDVCKYMHVRDSVVLLASGGHSCLLKIHNNKISLLGETLDDAAGEAF FT DKIARLMGLQYPGGPAIEMLASSGNPNAVEFPRALLTHFEEHNRYSFSFSGLKTAVGRV FT VERIKSNPAHSIPKIEDIAASFQEAVADVLTAKTVAAALASDVDLIVMGGGVAANNRIR FT EMLCERAKIHGLDVKIPPIALCTDNGAMIAAAGSWLMQLGYNPSHSRFSPVSIMPLTQM FT VV" FT misc_feature 209859..210987 FT /note="Glycoprotease family Score = 376.6 E-value = FT 1.7e-110" FT repeat_region 211107..212101 FT /note="Non-coding degenerate repeat region in Repeat FT Cluster 1 (RC1)." FT CDS 212254..213477 FT /transl_table=11 FT /locus_tag="TW171" FT /product="conserved hypothetical protein" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein SCO3406 or SCE9.13c SWALL:Q9X8I6 (EMBL:AL049841) FT (352 aa) fasta scores: E(): 2.6e-11, 32.66% id in 401 aa" FT /db_xref="GOA:Q83I94" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q83I94" FT /protein_id="CAD66850.1" FT /translation="MLHRPRITPAVANARRAMLNTLPADLHNQLVLIALSGGRDSLAAM FT VIASWVIPRLNGRVGAVVVDHGLQENSARIADEVRIRAEQFALNPILIKRVSPSRVSAG FT PEASARIARYAAFYDTLEETKAYAIILAHTLDDQAETVLLGLMRGSGPSSLRGMKAVSY FT TPEDCRYMNNKACNSVTAVYAHNTQRCSCDSRPYPPPPEPRNENRSYFPHPSCKCVEGS FT ATRFTNADIDSRFGVFIRPFLDITRHETGKICEFYGLDYWNDPHNEDVRFSRVRIRHNV FT MPVLENEIGPGVKYALSRTAKLAQLDTEYLDHLSNELLDEIASKESDWSIRLPINTLQK FT TPVPIRLRVIRLAALQYFTVSLSFKHTRQIERLLCSSCDIKHVNLPRLITAQRVGNYIY FT MHTLRGKL" FT CDS 213482..213985 FT /transl_table=11 FT /gene="hpt" FT /locus_tag="TW172" FT /product="hypoxanthine phosphoribosyltransferase" FT /EC_number="2.4.2.8" FT /note="Similar to Salmonella typhimurium hypoxanthine FT phosphoribosyltransferase Hpt or Stm0170 SWALL:HPRT_SALTY FT (SWALL:O33799) (178 aa) fasta scores: E(): 7.7e-25, 46.01% FT id in 163 aa, and to Streptomyces coelicolor putative FT hypoxanthine phosphoribosyltransferase HprT or SCO3405 or FT SCE9.12c SWALL:Q9X8I5 (EMBL:AL049841) (187 aa) fasta FT scores: E(): 7.9e-35, 54.81% id in 166 aa" FT /db_xref="GOA:Q83I93" FT /db_xref="HSSP:1J7J" FT /db_xref="InterPro:IPR002375" FT /db_xref="UniProtKB/TrEMBL:Q83I93" FT /protein_id="CAD66851.1" FT /translation="MKPLLSEAVIHRRLAQLALQIDEDYRGTSIVLLGVLKGSIMLMAD FT LSRLLSSDLRIEWVTLSSYGNDTVSSGSIRIVHDLDADIRDRHVLIIEDIVDSGLTLGW FT LLAKMRERRPASIEACVLLRKPHARGTDVRYLGFDIPDEFVIGYGMDYAEKYRNLKSVY FT VLEQ" FT misc_feature 213482..213920 FT /note="Phosphoribosyl transferase domain Score = 63.3 FT E-value = 3.6e-16" FT misc_feature 213746..213784 FT /note="PS00103 Purine/pyrimidine phosphoribosyl FT transferases signature." FT CDS 213988..215988 FT /transl_table=11 FT /gene="ftsH" FT /locus_tag="TW173" FT /product="FtsH-like putative cell division protein" FT /EC_number="3.4.24.-" FT /note="Similar to Streptococcus pneumoniae cell division FT protein FtsH or sp0013 SWALL:FTSH_STRPN (SWALL:O69076) (652 FT aa) fasta scores: E(): 2.5e-86, 54.38% id in 502 aa, and to FT Streptomyces coelicolor cell division protein FtsH homolog FT FtsH2 or SCO3404 or SCE9.11c SWALL:Q9X8I4 (EMBL:AL049841) FT (668 aa) fasta scores: E(): 4.5e-119, 55.12% id in 664 aa" FT /db_xref="GOA:Q83I92" FT /db_xref="HSSP:1IXZ" FT /db_xref="InterPro:IPR003960" FT /db_xref="UniProtKB/TrEMBL:Q83I92" FT /protein_id="CAD66852.1" FT /translation="MSKITKSPVLYIVLLVVGVWVAVNLFLTNAYQSIRTEEGLELIKS FT DSLVSVRIVDRDQRVDLELATPYKNHGTKVQFNYVSQRATEIVNAVNKAKIKDGFTDEV FT PAPSVWGSIISMLLPIAAIGLFLWFMAGPQAAGGRGIAQFSRMRSRLVSKEMPKVRFTD FT VAGADEAVEELQEIKDFLSDPDKYRKLGARIPKGVLLFGPPGTGKTLLARAVAGEAGVP FT FFSISGSDFVEMFVGVGASRVRDLFEQAKQNSPSIIFIDEIDAVGRRRGSGFGGGHDER FT EQTLNQLLVEMDGFDVKTNIILIAATNRSDVLDSALLRPGRFDRHVAIDAPNLQGRLKI FT LQVHARTKPVSKSVDLEVLARKTPGFTGADLANVLNEAALLTARSNAQIIDDRALDEAV FT DRVMAGPQRRSRVMTDHEKLVTAYHEAGHALTAAAMRYSDPVTKVTILPRSRALGYTMV FT MPVQDRYSVTRNELLDKLAYAMGGRAAEELVFHDPTTGASNDIEKATSIARKMVTEFGL FT SKDLGAVKFGNAHNETLMGVGQMTARDYSEVTAERIDVQVRALIQNARDEAWEVISNNR FT NLLDDLALNLLEKETLNQDEIAEIFKGVRKLPERHVWQSAPNREPSNKPPVKYSAMGPD FT SEVTAKSPKRTSNRRRLPSARRPRKDSETQE" FT misc_feature 213988..214083 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.907) with cleavage FT site probability 0.640 between residues 32 and 33" FT misc_feature order(214015..214068,214312..214380) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 10-27 and 109-131" FT misc_feature 214576..215137 FT /note="ATPase family associated with various cellular FT activities (AAA) Score = 328.5 E-value = 5.6e-96" FT misc_feature 214591..214614 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 214888..214944 FT /note="PS00674 AAA-protein family signature." FT misc_feature 215155..215785 FT /note="Peptidase family M41 Score = 336.5 E-value = FT 2.1e-98" FT CDS 216002..216547 FT /transl_table=11 FT /gene="folE" FT /gene_synonym="mtrA" FT /locus_tag="TW174" FT /product="GTP cyclohydrolase I" FT /EC_number="3.5.4.16" FT /note="Similar to Bacillus subtilis GTP cyclohydrolase I FT FolE or MtrA SWALL:GCH1_BACSU (SWALL:P19465) (190 aa) fasta FT scores: E(): 1.9e-12, 33.53% id in 167 aa, and to Bacillus FT halodurans GTP cyclohydrolase I FolE or MtrA or bh1646 FT SWALL:GCH1_BACHD (SWALL:Q9KCC7) (188 aa) fasta scores: E(): FT 2.6e-14, 32.25% id in 186 aa" FT /db_xref="GOA:Q83I91" FT /db_xref="HSSP:1IS8" FT /db_xref="InterPro:IPR018234" FT /db_xref="UniProtKB/TrEMBL:Q83I91" FT /protein_id="CAD66853.1" FT /translation="MTKLCRFESGSAQSAVANLLSALGQDVGRLKETPSIASSGLESLI FT SGSETNPADCLVDLIPNTQKGIVILRDIPFRSICEHHLLPFVGTANLLYEPGKFLAGLG FT NLTSLVRCAARRLSIQERVTDQIADAIYTGLCARRVLVSLAARHTCILDEAGNTEVTTF FT AHRGIGDADIISFMTIIR" FT misc_feature 216197..216482 FT /note="GTP cyclohydrolase I Score = 46.7 E-value = 3.8e-11" FT CDS 216584..218881 FT /transl_table=11 FT /gene="folP" FT /gene_synonym="sul" FT /locus_tag="TW175" FT /product="dihydropteroate synthase" FT /EC_number="2.5.1.15" FT /note="Similar to Bacillus subtilis dihydropteroate FT synthase Sul SWALL:DHPS_BACSU (SWALL:P28822) (285 aa) fasta FT scores: E(): 8.7e-28, 40.61% id in 261 aa, and to FT Streptomyces coelicolor putative dihydropteroate synthase FT FolP or SCO3398 or SCE9.05 SWALL:Q9X8H8 (EMBL:AL049841) FT (288 aa) fasta scores: E(): 1.7e-38, 46.26% id in 268 aa" FT /db_xref="GOA:Q83I90" FT /db_xref="HSSP:1EYE" FT /db_xref="InterPro:IPR000550" FT /db_xref="UniProtKB/TrEMBL:Q83I90" FT /protein_id="CAD66854.1" FT /translation="MMNMSYTPDPFPPPNVMGILNITDDSFSDGGLFLDPSAAITQGRK FT LFAEGASIIDVGGESTRPGAERISVEEEKKRVLPVVRELLSEGIHVSLDTMNADTAKEG FT LSMGVAIINDVSAGKADPDMLRVIADAGCKYIAMHWRGHSMFMDSLAHYDDVVSDVLRE FT LKFDIERITAAGVKSDQIILDPGFGFSKTSDHNWQLFRNLDCFVKLGFPVLIGLSRKRF FT LSRVFKGHDFSPKDSKNVGGLDNREILARDLPSGILSAIAITRGAWGVRVHDVASAHTA FT LRTLQLAQYGSVYQAHKRAANTGIDTAIPGQGNTDDTTASSNHTNNSETGASLKSGVSQ FT VRNMIAPPVIKIRSLRVYAYHGVYRSERDYGQQFIIDADIQLKHFPEDKIDSTLDYDSL FT TGKFVQYATASSVNLIETLADHLAKIAVLDPMVEWVSLSITKPNPPLAYMKQSNTAACH FT AMHKPDTRGDYAKEHTNLTGLQLSCTVRKVRSESVTRVYIGIGANVGNCLDNVQRAIKD FT IADHPMIELVSLGRLFRTTAVVGESLDESLPVFLNTAIAIDTALSMQDLLALMLCIEKK FT LGRTRHSRTRHSLSSAQDAHQADSTSDNPNQLHYPCAGRQGIQQPLHSSTLAHTQDGFV FT NRHIDLDILLAEGVQITEHGLCIPHPRLSKRAFALLPLESIDPDLHIPGHGPITDLIHG FT LPEDQISSVATLRDSGYELFRHSITRLNNCSAHNKAYVTPSAGQNYDSEQDFDAGLSHT FT ESRGKTEPHGKI" FT misc_feature 216629..216676 FT /note="PS00792 Dihydropteroate synthase signature 1." FT misc_feature 216638..217412 FT /note="Pterin binding enzyme Score = 325.9 E-value = FT 3.3e-95" FT misc_feature 216731..216772 FT /note="PS00793 Dihydropteroate synthase signature 2." FT misc_feature 217631..217958 FT /note="Dihydroneopterin aldolase Score = 59.2 E-value = FT 6.1e-15" FT misc_feature 218066..218612 FT /note="7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase FT (HPPK) Score = 100.9 E-value = 1.7e-27" FT CDS 218878..219327 FT /transl_table=11 FT /locus_tag="TW176" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NR9" FT /protein_id="CAD66855.1" FT /translation="MNKTAALVAALIVFSAVIAALASQVLSELGYSVFVPSYTFVFACL FT ALALIQIILAIRIKLVLVKGKRAINPAFAYRILALARSYILAGSLFFGFFSGTALYFVR FT GGFIPEKFYLLIPPAIASLIVIIAGVISKFLLRIPKNHGAAANLE" FT misc_feature 218878..218958 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.468 between residues 27 and 28" FT misc_feature order(218890..218949,218977..219045,219106..219174, FT 219217..219285) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 5-24, 34-56, 77-99 and FT 114-136" FT CDS 219552..220313 FT /transl_table=11 FT /locus_tag="TW177" FT /product="putative ABC transporter ATP-binding subunit" FT /note="Similar to Lactococcus lactis NisF protein NisF FT SWALL:Q48635 (EMBL:Z29363) (225 aa) fasta scores: E(): FT 2.3e-15, 32.57% id in 221 aa" FT /db_xref="GOA:Q83I89" FT /db_xref="InterPro:IPR003439" FT /db_xref="UniProtKB/TrEMBL:Q83I89" FT /protein_id="CAD66856.1" FT /translation="MAKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAG FT DCVGLIGPNGGGKTTLINLILGFMPPSSGAIAFHSVLSTPTQRGLNTGIMLDIPAVPYG FT LSVIRYFSLEARHRQLNDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLMLSP FT EFLVLDEPTNSLDIEGITWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLR FT YNGDLADLAKDGGDLEKAYFRLTDDSAVQYG" FT misc_feature 219684..220209 FT /note="ABC transporter Score = 108.4 E-value = 9.9e-30" FT misc_feature 219705..219728 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 219984..220028 FT /note="PS00211 ABC transporters family signature." FT CDS 220402..221079 FT /transl_table=11 FT /locus_tag="TW178" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NR8" FT /protein_id="CAD66857.1" FT /translation="MTALSNWLLVSQGGVSHESVSKAIVSMPVSTITIFIPAVGIMFIS FT RDFVSGYILRATLLLGDWRRFFFLRAIEAVVLSALFVLAICVLSVLFSSVFLAFAGYPV FT GKAFSSDLFLSLLSCIPVSCVVGLMAYFLGWALRGAVVFMSVYFPYVFVADPVLSLLIP FT NFVWFSYPGAVTRATNFFPTTPGEHALSGYTSPYIGFSVVLAYCAVAFLLAYFRNTRRG FT GIL" FT misc_feature order(220468..220536,220624..220692,220735..220803, FT 220837..220905,220981..221049) FT /note="5 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 23-45, 75-97, 112-134, FT 146-168 and 194-216" FT CDS 221086..221778 FT /transl_table=11 FT /gene="ung" FT /locus_tag="TW179" FT /product="uracil DNA glycosylase" FT /note="Similar to Streptomyces coelicolor uracil DNA FT glycosylase Ung or SCO1114 or 2SCG38.07 SWALL:Q9EX12 FT (EMBL:AL445503) (225 aa) fasta scores: E(): 2.6e-52, 59.17% FT id in 218 aa, and to Homo sapiens uracil-DNA glycosylase, FT mitochondrial precursor Ung or Dgu or Ung15 SWALL:UNG_HUMAN FT (SWALL:P13051) (304 aa) fasta scores: E(): 6.1e-26, 42.18% FT id in 192 aa" FT /db_xref="GOA:P67079" FT /db_xref="HSSP:1EMH" FT /db_xref="InterPro:IPR005122" FT /db_xref="UniProtKB/Swiss-Prot:P67079" FT /protein_id="CAD66858.1" FT /translation="MGYLHVLAQRGVIHATWVSALEPVSSNLAAMGDCLRSLRSKGESF FT LPAPRNILRAFRYPFDSVRVLIVGQDPYPTQGHPIGLSFAVDHKVRPLPGSLQNIYTEY FT RSDLNLDPPQHGDISLWSERGVMLLNRTLTVRPGIPSSHRGLGWEEITQTAVRALAARD FT VPLIAILWGRHAQELKSVLQSDRVAILESVHPSPMSATRGFFGSKPFSKANDLLRDLGS FT APIDWRLT" FT misc_feature 221251..221737 FT /note="Uracil DNA glycosylase superfamily Score = 170.1 FT E-value = 2.7e-48" FT misc_feature 221275..221304 FT /note="PS00130 Uracil-DNA glycosylase signature." FT CDS 221811..222749 FT /transl_table=11 FT /gene="ribF" FT /locus_tag="TW180" FT /product="riboflavin biosynthesis protein RibF [includes: FT riboflavin kinase]" FT /EC_number="2.7.1.26" FT /note="Similar to Escherichia coli riboflavin biosynthesis FT protein RibF [includes: riboflavin kinase] or b0025 or FT z0029 or ecs0028 SWALL:RIBF_ECOLI (SWALL:P08391) (313 aa) FT fasta scores: E(): 8.3e-30, 35.33% id in 317 aa" FT /db_xref="GOA:Q83I88" FT /db_xref="HSSP:1N05" FT /db_xref="InterPro:IPR002606" FT /db_xref="UniProtKB/TrEMBL:Q83I88" FT /protein_id="CAD66859.1" FT /translation="MRVFRSFDCLGRDKRTALTIGKFDGVHLGHRRLLERIVALQNQDT FT SALVVTFDRDPKTFFKKDMSFVPLCSLEQKLSLLENCNIPNCLILRFDDEFASMSAEDF FT VHKVLLEKLNMSSIVIGDGFRFGARGLGDAMLLEKLARELGFYLEVIPKIQFGKTNISS FT TLIRKFLSLGQAGNASSCLGRNHVCTGTVVHGKKRGRELGFPTANLGKDVSGFIPADGV FT YIGRIISDRSYPAAVSIGRNPTFGDLEFSQIEAHALYEDISSLDLYGRRIDVEFIAHLR FT DTMLYKSIDSLKAAIRSDVERCKEYFSTTVG" FT misc_feature 222351..222732 FT /note="Riboflavin kinase / FAD synthetase Score = 125.2 FT E-value = 8.4e-35" FT CDS 223106..223651 FT /transl_table=11 FT /locus_tag="TW181" FT /product="putative secreted protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NR6" FT /protein_id="CAD66860.1" FT /translation="MVMSVVKMRILAALLTIPLMFLIAIGPVSAETQHVQETAIRLTAD FT DTNQIIKELEQAGFTKQVTGNKRQETITLTKDGVTVTLTHVTQQTQTRLSWGDDPWGFY FT IKLEWHEQVALAAGTLAAGGGAGLALKAALKIAVKAGTAFLAGLEVVDKLSDIIGAGPC FT PPFQPRYIRFDPFRTKCN" FT misc_feature 223106..223195 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.992 between residues 30 and 31" FT misc_feature 223133..223201 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 10-32" FT CDS 223721..224497 FT /transl_table=11 FT /locus_tag="TW182" FT /product="putative integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NR5" FT /protein_id="CAD66861.1" FT /translation="MNRQSSFFPLLTGFFTYLFLLTRPHKRRLFMAGLVRKYYRDSTAR FT TLIFDFYEYSVEGGILCLLLGVPSYIQLTEPLLLALVVALVALCVALIMHHSQYTLVLF FT DDWGIDKRSFLLRYSYYSQTPSFQNPTKRRQILLLDTVTRYGSKWSRVYVATMAVCIFF FT LVGTPISAWYLGALSFFACLFYTCFFTILPSIIFPFAFDGFPALLVRKLLYNLHIRRHG FT PIPKELTDMVTQAYEIYPERLYPWFRSRKNQKCESR" FT misc_feature order(223730..223783,223949..224017,224174..224242, FT 224255..224323) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 4-21, 77-99, 152-174 and FT 179-201" FT CDS 224723..225307 FT /transl_table=11 FT /locus_tag="TW184" FT /product="putative peptidase" FT /note="Similar to Aeromonas hydrophila type 4 prepilin-like FT proteins leader peptide processing enzyme [includes: leader FT peptidase tapD] SWALL:LEP4_AERHY (SWALL:P45794) (290 aa) FT fasta scores: E(): 1.5e-05, 29.44% id in 197 aa, and to FT Escherichia coli leader peptidase HopD SWALL:HOPD_ECOLI FT (SWALL:O68932) (155 aa) fasta scores: E(): 0.0017, 32.7% id FT in 159 aa" FT /db_xref="GOA:Q83NR4" FT /db_xref="InterPro:IPR000045" FT /db_xref="UniProtKB/TrEMBL:Q83NR4" FT /protein_id="CAD66862.1" FT /translation="MTKPVAYSIYALIVILTGIGLGIIGLPFATLAFIAIFVSTPALFR FT ADIRELRLPNAITLPLIAIGIVALLADQIVHPNLDIVFSALIAIGLSSFLFIVSIFGGM FT GMGDVKLSLALLLCAANLGPAFPIIAISSAFLVAFCFCILIFVGLFRFFKNSGRISCLP FT FGPFLLLGFWTTVIVWGIDRWTDVDILRIIW" FT misc_feature 224723..224857 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.981) with cleavage FT site probability 0.862 between residues 45 and 46" FT misc_feature order(224741..224836,224879..224932,224969..225037, FT 225095..225163,225197..225265) FT /note="5 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-38, 53-70, 83-105, 125-147 FT and 159-181" FT CDS 225473..226039 FT /transl_table=11 FT /locus_tag="TW186" FT /product="putative integral membrane protein" FT /db_xref="UniProtKB/TrEMBL:Q83NR3" FT /protein_id="CAD66863.1" FT /translation="MYITWITPQVRPITPYIVTCALILSPARYRYRITVTPSQQAHTLS FT LQSVAHGQRLIYLDLEMWSVRFFRLVCLRLGVLLLLVLVSSLFSLFGTAGVTFFLGGVP FT VGLLLGISTLTLFYLSIRLMFLSRIYLAISGVTNFAVVVFYGRNIPADQVVIWIWMASL FT PIICGTILSVPLFGSRRYGASAPDA" FT misc_feature order(225680..225748,225761..225829,225848..225907, FT 225935..226003) FT /note="4 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 70-92, 97-119, 126-145 and FT 155-177" FT CDS 226082..226408 FT /transl_table=11 FT /locus_tag="TW187" FT /product="ferredoxin" FT /note="Similar to Streptomyces griseus ferredoxin FT SWALL:FER_STRGR (SWALL:P13279) (105 aa) fasta scores: E(): FT 1.8e-33, 79.2% id in 101 aa" FT /db_xref="GOA:Q83NR2" FT /db_xref="HSSP:1BD6" FT /db_xref="InterPro:IPR000813" FT /db_xref="UniProtKB/TrEMBL:Q83NR2" FT /protein_id="CAD66864.1" FT /translation="MTYVIAFPCVDLKDRACIDECPVDCIYEGGRSLYINPDECVDCGA FT CEPVCPVEAIYYEDDLPEEWGEYYRANVEFFDEIGSPGGAAKLGPVDFDHPIIAQLPKS FT SDSV" FT misc_feature 226178..226247 FT /note="4Fe-4S binding domain Score = 38.9 E-value = 8e-09" FT misc_feature 226199..226234 FT /note="PS00198 4Fe-4S ferredoxins, iron-sulfur binding FT region signature." FT CDS 226431..227699 FT /transl_table=11 FT /locus_tag="TW188" FT /product="putative integral membrane protein" FT /note="Weakly similar to Streptomyces coelicolor putative FT integral membrane protein SCO1752 or 2SCI34.05 SWALL:Q9EWX4 FT (EMBL:AL445403) (396 aa) fasta scores: E(): 4.1e-05, 24.72% FT id in 364 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NR1" FT /protein_id="CAD66865.1" FT /translation="MSSRFSLFTPRCLLRFACIIAQFTKRVFLRFWNGHWVVTILGIYI FT ASRIVTTILVLIVSTNQQPTFAISHNPDYFAFANIWDARWYESIVYFGYPKVLPTNAFG FT YVGQNAWAFLPGYPIAVKLVMFLFGLGFQKAAVAISLIFGFLTCIVMYLLQRSLFSRDR FT AMLCVLLFAFNPLSPLFQFGYADTYSLFFVLLALWFLRLREYALLVAVLPGIAFSRPIA FT LAFALGLILLFLMRCVKSRQGKEEFPKKDFMSLLIASVVAVILGFAWPVIAGIFSGRLD FT AYLATELSWRIYMQSDPHFAIFQPWFLAFYFYATYFGMPGWIGILTAAVIILILLFVLF FT CYIRRLGDEIFSWSAAYIVYILAVFFPQSSVFRIALPLSPALVLLARRKSIVIIFLVLS FT VILQFVWLDVLWVISPGGDPAPP" FT misc_feature order(226536..226604,226758..226826,226839..226907, FT 226926..227030,227073..227132,227190..227258, FT 227391..227459,227478..227546,227604..227672) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 36-58, 110-132, 137-159, FT 166-200, 215-234, 254-276, 321-343, 350-372 and 392-414" FT repeat_region 227946..227956 FT /note="(g)11" FT CDS 228065..228706 FT /transl_table=11 FT /locus_tag="TW189" FT /product="putative membrane protein" FT /note="No significant database matches. Possible FT coiled-coil region at residues 42-80." FT /db_xref="UniProtKB/TrEMBL:Q83NR0" FT /protein_id="CAD66866.1" FT /translation="MRRKLLPVLLFSVFLWVCLPAQSAQAFLFDGKNNIFKQLQQTAEK FT KLKELKGTAQKAVNTVKKKVEQAKHTAETKVKELQNTVATAVHNAVQPKPQKRPAKPVA FT TKAPPAPKPSSSSAPSRVSPPTPPTHSSSASASVTHSSSIPSATHSSNSSSARESSGAT FT STSSSSADAGKSVAAESSPGLLIPAAITAAVTVAITSITAVMYIVFSRFL" FT misc_feature 228065..228133 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.998) with cleavage FT site probability 0.405 between residues 23 and 24" FT misc_feature order(228077..228145,228626..228694) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 12-34 and 195-217" FT CDS complement(228948..229565) FT /transl_table=11 FT /gene="mdmC" FT /locus_tag="TW190" FT /product="putative O-methyltransferase" FT /EC_number="2.1.1.-" FT /note="Similar to Streptomyces mycarofaciens FT O-methyltransferase MdmC SWALL:MDMC_STRMY (SWALL:Q00719) FT (221 aa) fasta scores: E(): 8e-05, 28.57% id in 175 aa" FT /db_xref="GOA:Q83I87" FT /db_xref="InterPro:IPR002935" FT /db_xref="UniProtKB/TrEMBL:Q83I87" FT /protein_id="CAD66867.1" FT /translation="MKAEINWNFTQSLPKDTEEEKHLRLLSEELYIQSICPAIGAHIKT FT QVAALPAPQVLEIGTGIGLSALKMVSVNRKAHITTIEVNPDFYNRAKNNLTNYFSCLRF FT INSNALEVIPRMNRNMYDLVLIDANPRDVLNYFELALGVVKSGGAILVPHALWQGKVAS FT PVYKDEPEISFRALIHEVVNSETFVSCLSPIGDGILTVTKPK" FT misc_feature complement(228956..229538) FT /note="O-methyltransferase Score = -50.0 E-value = 1.3e-08" FT CDS 229601..229825 FT /transl_table=11 FT /locus_tag="TW191" FT /product="putative secreted protein" FT /note="N-terminus similar to that of Caulobacter crescentus FT hypothetical protein Cc2002 SWALL:Q9A6T1 (EMBL:AE005873) FT (200 aa) fasta scores: E(): 5.2, 31.91% id in 47 aa" FT /db_xref="UniProtKB/TrEMBL:Q83NQ9" FT /protein_id="CAD66868.1" FT /translation="MHVLGIGLDKIVIIAFFAALLLSPSQLLAYAKKIGFYAGKIRVMS FT DLVKKQFVDATSERKVPVGDFSVTDDEAT" FT misc_feature 229601..229693 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.889) with cleavage FT site probability 0.511 between residues 31 and 32" FT misc_feature 229631..229690 FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 11-30" FT CDS 229953..230495 FT /transl_table=11 FT /locus_tag="TW192" FT /product="possible integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NQ8" FT /protein_id="CAD66869.1" FT /translation="MPKTNIKFLIITLSVIFSLIFIATPTYATTSVTTDKAVATTTEPK FT ANQIIKELEQAGFTKQVTGNKRQETITLTKDGVTVTLTHVTQQTQTRLSWGDDPWGFYI FT KLEWHEQVALAAGTLAAGGGAGLALKAALKIAVKAGTAFLAGLEVVDKLSDIIGAGPCP FT PFQPRYIRFDPFRTKCG" FT misc_feature 229953..230036 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 1.000) with cleavage FT site probability 0.780 between residues 28 and 29" FT misc_feature order(229971..230039,230283..230351) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 7-29 and 111-133" FT CDS 230519..231298 FT /transl_table=11 FT /locus_tag="TW193" FT /product="possible integral membrane protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83NQ7" FT /protein_id="CAD66870.1" FT /translation="MPKTTTSVTQPRQSSFFPLLTGFFTYLFLLTRPHKRRLFMAGLVR FT KYYRDSTARTVLSTTDIFLFSFVITFAIAVLIGMSSALYFIIASVPGAVVYESSLWQFV FT WWSSILVSFVVAYLYLQIFSPSDRSFLLRYSYYSQTPSFQNPTKRRQILLLDTVTRYGS FT KYYRDLAKFWLTLLAILVFIGALFIFVTQNFSILNPIFLLLFLLSCLISFLVIDSLSGS FT LVRKLLYNLHIRRHGPIPKELTDIVTQAYEIYPQVTT" FT misc_feature order(230561..230608,230708..230776,230819..230887, FT 231023..231091,231119..231187) FT /note="5 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 15-30, 64-86, 101-123, FT 169-191 and 201-223" FT CDS complement(231435..232766) FT /transl_table=11 FT /gene="aroA" FT /locus_tag="TW194" FT /product="3-phosphoshikimate 1-carboxyvinyltransferase" FT /EC_number="2.5.1.19" FT /note="Similar to Mycobacterium tuberculosis FT 3-phosphoshikimate 1-carboxyvinyltransferase AroA or Rv3227 FT or mt3324 or mtcy20b11.02 SWALL:AROA_MYCTU (SWALL:P22487) FT (450 aa) fasta scores: E(): 1.6e-52, 42.4% id in 441 aa" FT /db_xref="GOA:Q83I86" FT /db_xref="InterPro:IPR006264" FT /db_xref="UniProtKB/Swiss-Prot:Q83I86" FT /protein_id="CAD66871.1" FT /translation="MAKTEMYQPPLGNRALFKMSIPGSKSLTNRHLIIAAIASGETTIH FT NLLESRDTNLMIEGLRRIGCKIEKLNHTGTHDTGVISPHCTCLNDLIQPSDVRIIPSKH FT YTCSTKIDCGLAGTVMRFLPVLAGLCKGSVEFFGDDQAIRRPMDGTLHALRKLGVQVDG FT DRIPFTVHGRGEIEGGALETTEHSSSQFISGLLLSACRFKNGLTLKHIGNPLPSRPYID FT MTVEVMREWGINVTHSDGVWAVTPKELTGKHITIEPDLSNAAPFMIGAIVTGGSATIQN FT WPSKTSQPGKYLEAILPQFGAEITKTANTITVSGTGNITGIRADLGHIGELVPNLVALA FT TLAETPSVFYNIGHIRYHETDRIEALVNEISSLGGTITAGKDYIKITPTTLTRSGVWKT FT YKDHRMATSGAIIGLRHKLTIEDIECTSKTFPRFADLWSGAFGK" FT misc_feature complement(231458..232721) FT /note="EPSP synthase (3-phosphoshikimate FT 1-carboxyvinyltransferase) Score = 326.9 E-value = 1.7e-95" FT CDS 232840..234861 FT /transl_table=11 FT /gene="recG" FT /locus_tag="TW195" FT /product="ATP-dependent DNA helicase RecG" FT /EC_number="3.6.1.-" FT /note="Similar to Staphylococcus aureus ATP-dependent DNA FT helicase RecG SWALL:RECG_STAAU (SWALL:O50581) (686 aa) FT fasta scores: E(): 3.9e-62, 32.43% id in 666 aa" FT /db_xref="GOA:Q83I85" FT /db_xref="HSSP:1GM5" FT /db_xref="InterPro:IPR014001" FT /db_xref="UniProtKB/TrEMBL:Q83I85" FT /protein_id="CAD66872.1" FT /translation="MASLLAKEFGISRVIDLLTYYPRRYICRGKLTKLSELIPGDEVTI FT VGRVLSTEQRKTFSGANFLSVTLSDGENIIQLVFFHQPWRAENLKPGACGLFSGKVTEF FT NNKKQLSHPEYELFSSEPTREQIQKWNEQIIPIYRACIACPSWKIARAVDLALEAVKGQ FT TVDFMSGNYGYMSVEKAFYVIHHPTDNEELEAAKESLRFFEAFLLQSALLHRKRFRNRA FT SATPFIRKNGGFLERFDARLEFSQTNDQLRAADEIFEDLSLSEPMTRLLHGEVGSGKTL FT VAIRAMLLAADNDMQAVLVAPTEVLAKQHHRNLTRMLGHELCAEIQPSLLLGREKHTLR FT IASGRSKIIIGTHSVFSKKTVFHNLALVVIDEQHRFGVGQRDELLLKGDSPHLLMLSAT FT PIPRTVALSLLNFIAISEIKTPPSGKAEISTHVVPLAEKPQWGREVIRRISEEIQKGHQ FT VFVVAPVIEQSRTGAASISALLRELEETPLLQGAKISRLHGKLTAAECEKSMEEFSCGA FT SDILLSTTMIEVGIDVPNATAMVIVSADRFGIAQLHQLRGRIGRGNLPGVCLLVTNAPE FT GSAARSRLDLVARTHDGFSLAEIDMKMRREGDLLGLGQSGQGNYRLLRLDEDLQVLSDA FT RLHAEGIMENDIKLEKNKLLRLFLSQYLSGTNLSRLLS" FT misc_feature 232966..233191 FT /note="OB-fold nucleic acid binding domain Score = 47.9 FT E-value = 1.6e-11" FT misc_feature 233545..234124 FT /note="DEAD/DEAH box helicase Score = 98.8 E-value = FT 7.8e-27" FT misc_feature 233656..233679 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 234310..234526 FT /note="Helicase conserved C-terminal domain Score = 76.5 FT E-value = 3.9e-20" FT CDS 234982..235512 FT /transl_table=11 FT /gene="coaD" FT /locus_tag="TW196" FT /product="phosphopantetheine adenylyltransferase" FT /EC_number="2.7.7.3" FT /note="Similar to Escherichia coli phosphopantetheine FT adenylyltransferase CoaD or KdtB or b3634 or z5058 or FT ecs4509 SWALL:COAD_ECOLI (SWALL:P23875) (159 aa) fasta FT scores: E(): 3.8e-06, 33.13% id in 169 aa" FT /db_xref="GOA:Q83I84" FT /db_xref="HSSP:1O6B" FT /db_xref="InterPro:IPR014729" FT /db_xref="UniProtKB/Swiss-Prot:Q83I84" FT /protein_id="CAD66873.1" FT /translation="MSNRIAVVPGTFDPVTRGHMDILTRTSRIFNTLYVLVANNPDKTP FT LLPMHDRVDLVGQALEEYGFPRSEPKCDSESDRNGPIVKIHRFEKGLLVDCCKQLGATV FT IVRGLISADAHREASMAYANRNMSGIETVFILPDPPLSVVSSSMVRQLIALGGDISPYV FT PACVTRFFGTHSG" FT misc_feature 235000..235498 FT /note="Cytidylyltransferase Score = 56.8 E-value = 3.4e-14" FT CDS complement(235965..236714) FT /transl_table=11 FT /locus_tag="TW197" FT /product="putative membrane protein" FT /note="Similar to Streptomyces coelicolor putative integral FT membrane protein SCO3849 or SCH69.19c SWALL:Q9XA15 FT (EMBL:AL079308) (253 aa) fasta scores: E(): 9.6e-09, 25.6% FT id in 250 aa" FT /db_xref="InterPro:IPR005754" FT /db_xref="UniProtKB/TrEMBL:Q83NQ6" FT /protein_id="CAD66874.1" FT /translation="MIAKHTKRGVKFPRGEQAKPASGWSRIVMIFGELSMTAGVLVGIF FT YTWVLYIDSPLTAWEQGNSANLTASQFMRHRSDATETMPVTDRVKDYEDIAVLFVPRFG FT NKYKRVIRETTDVTRVLNSKTAGVGHYPHTALPGTSGNFAVAAHEVGWGAAFGKLSELR FT LGDKIYVLTPKGWYIYAYRSSEYVKPDGVNVLRPLPQSFAVPDETYIMTMTTCNPPFSV FT AERLIAYAVLEKWQADVPHEIVNIVNS" FT misc_feature complement(235997..236423) FT /note="Sortase family Score = 54.3 E-value = 1.9e-13" FT misc_feature complement(236568..236636) FT /note="1 probable transmembrane helix predicted for FT Unknown_CDS by TMHMM2.0 at aa 27-49" FT CDS 236982..237179 FT /transl_table=11 FT /gene="rpmF" FT /locus_tag="TW198" FT /product="50s ribosomal protein L32" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L32 RpmF SWALL:RL32_BACST (SWALL:P07840) (56 aa) FT fasta scores: E(): 4.3, 34.92% id in 63 aa, and to FT Mycobacterium tuberculosis 50s ribosomal protein L32 RpmF FT or Rv0979.1c or mt1007 or mtv044.07c.1 SWALL:RL32_MYCTU FT (SWALL:P58287) (57 aa) fasta scores: E(): 0.00062, 55.1% id FT in 49 aa" FT /db_xref="GOA:Q83I83" FT /db_xref="InterPro:IPR002677" FT /db_xref="UniProtKB/Swiss-Prot:Q83I83" FT /protein_id="CAD66875.1" FT /translation="MAVPKRKKSRANTRARRSQWKASVPGFARLEERGRPVFYLPHRAR FT RILDSNGNELFMEYKGRRVG" FT misc_feature 236985..237099 FT /note="Ribosomal L32p protein family Score = 17.6 E-value = FT 0.00057" FT CDS 237204..237851 FT /transl_table=11 FT /gene="rnc" FT /locus_tag="TW199" FT /product="ribonuclease III" FT /EC_number="3.1.26.3" FT /note="Similar to Escherichia coli ribonuclease III Rnc or FT b2567 or z3848 or ecs3433 SWALL:RNC_ECOLI (SWALL:P05797) FT (226 aa) fasta scores: E(): 3e-18, 35% id in 220 aa, and to FT Streptomyces coelicolor ribonuclease III Rnc or SCO5572 or FT SC7A1.16 SWALL:RNC_STRCO (SWALL:Q9ZBQ7) (272 aa) fasta FT scores: E(): 3.9e-26, 42.05% id in 214 aa" FT /db_xref="GOA:Q83I82" FT /db_xref="HSSP:1O0W" FT /db_xref="InterPro:IPR011907" FT /db_xref="UniProtKB/Swiss-Prot:Q83I82" FT /protein_id="CAD66876.1" FT /translation="MRKFNLTLPPGLLRTAFVHKSFSFENGACQNNERLEFLGDAVLGL FT VVSHYLFETCPEYTEGQLSAARSYIVSGTSIAQIAKELNLGQFMLLGKGEKLAGGMDKT FT SLLADLLESLIGAVMVDQGFESARDFVLALVGEKLRQVGEFSVDDPKTKLQKLTRTQLV FT YEVVTEGPPHSRTFKASVIVNEKRFFGQGSSKKQAQVAAAMSALASLENKSS" FT misc_feature 237300..237326 FT /note="PS00517 Ribonuclease III family signature." FT misc_feature 237300..237570 FT /note="RNase3 domain Score = 160.6 E-value = 1.8e-45" FT misc_feature 237651..237831 FT /note="Double-stranded RNA binding motif Score = 71.7 FT E-value = 1.1e-18" FT CDS 237969..239126 FT /transl_table=11 FT /locus_tag="TW200" FT /product="putative ABC transporter branched chain amino FT acid binding protein" FT /note="Similar to Pseudomonas aeruginosa leucine-, FT isoleucine-, valine-, threonine-, and alanine-binding FT protein precursor BraC or pa1074 SWALL:BRAC_PSEAE FT (SWALL:P21175) (373 aa) fasta scores: E(): 3.2e-22, 28.78% FT id in 337 aa" FT /db_xref="GOA:Q83NQ5" FT /db_xref="InterPro:IPR000709" FT /db_xref="UniProtKB/TrEMBL:Q83NQ5" FT /protein_id="CAD66877.1" FT /translation="MFFSGCFGSGDNKSSAEHIVLPKVTAPVSFKNALFPAGDGKAVCP FT KGLSIAYVGIVTGPNAAFGKSINEAFQLAVKQHNDNNPGCQVTGKVFDTEGSPDKAPGV FT VAQVIGDSSIVAVLGPAFSGENQAVGGIFETARLVHITPSATLPTLSSHGWKTFFRAAS FT TDLEQSTGVIALLEKLEAKKTFVVSDDSAYGKFLGDLVKKGVDLAGSDGIITGSRDFSS FT VVAKVVSSGADSVFFAGYYPEAAAFFTQLRGAGFNGYLVVPDGSLDRNLSKLAGQAAVG FT VYAVCPCTDDSQVAGFGDAMKKAYGHYPGIYSSSAYDVTTILLRGIDSGRTSRSSLLDW FT VRGYDAYGVSGHYKFKANGDLQHTRLYFYRFDESGAPVLVGEYSK" FT misc_feature 238092..239115 FT /note="Receptor family ligand binding region Score = -7.8 FT E-value = 4.8e-05" FT CDS 239174..240178 FT /transl_table=11 FT /locus_tag="TW201" FT /product="putative ABC transporter branched chain amino FT acid transport permease" FT /note="Similar to Escherichia coli high-affinity FT branched-chain amino acid transport system permease protein FT LivH or b3457 or z4827 or ecs4304 SWALL:LIVH_ECOLI FT (SWALL:P08340) (308 aa) fasta scores: E(): 1.1e-30, 42.05% FT id in 302 aa" FT /db_xref="GOA:Q83NQ4" FT /db_xref="InterPro:IPR001851" FT /db_xref="UniProtKB/TrEMBL:Q83NQ4" FT /protein_id="CAD66878.1" FT /translation="MLLSLDYLLSQSWITFDVASFIKGFGFATVEGLTFGAIYALIAVG FT YTVVYGVLGLINFAHAGVFVTGCYALVFTLSALGFSSFPSKKPIFIVLIYVLIAVFVSI FT LAAAAVAFLVERVAYKPLRKRNAPNLAFLITAIGASLTISNLFFLRSPNPEPALSIFTP FT VPLFKFFGATVTSFNVVTILAAVILMFLVDWFIRRTRFGRGIRAVAQDPNTASLVGVNP FT ERVIALTFVLGGVIAGAASLFYVLKVPSGVVYNADIVLGLKAFAAAVLGGIGSIRGALL FT GGLLLGLFSNWGALLLGNSQWGDVSVFVLLLLVLLFRPSGILGRSGLSAKSRM" FT misc_feature 239246..240152 FT /note="Branched-chain amino acid transport system / FT permease component Score = 127.1 E-value = 2.3e-35" FT misc_feature order(239270..239338,239351..239419,239447..239515, FT 239552..239620,239678..239746,239843..239911, FT 239924..239992,240011..240064,240092..240160) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 33-55, 60-82, 92-114, FT 127-149, 169-191, 224-246, 251-273, 280-297 and 307-329" FT CDS 240175..241269 FT /transl_table=11 FT /locus_tag="TW202" FT /product="putative ABC transporter branched chain amino FT acid transport permease" FT /note="Similar to Escherichia coli high-affinity FT branched-chain amino acid transport system permease protein FT LivM or b3456 SWALL:LIVM_ECOLI (SWALL:P22729) (425 aa) FT fasta scores: E(): 2.9e-14, 36.19% id in 326 aa" FT /db_xref="GOA:Q83NQ3" FT /db_xref="InterPro:IPR001851" FT /db_xref="UniProtKB/TrEMBL:Q83NQ3" FT /protein_id="CAD66879.1" FT /translation="MMGFLSSVMRWWKGMSRPQQWFFLLPFVVLVYLLPIINPPVITTE FT PGNNFPISLFTMAIYALAAVGLNVVVGYAGLLDLGYIAFFAVGAYVSAVFTSPDSPYVK FT IPYLWTIPVAIFTAMVFGAALGVPTLRLRGDYLAIVTLGFGEIVRIMATVIPALRGNLG FT FSNVGHPPGDYPSGQPIFTPDNGVAWYWVAITVVIFVLVIVGNLERSIVGRNWFAICQD FT EDAAEVMGVNTFSFKVWAFAIGAAIGGLSGSLQAAQTGFVNNQRFDVATSVLFLVAVVL FT GGSGNKFGAAIGGALVAYIPLRFTEIAQYKYLIFGVCLILLMLFRHEGLFPMKANLFSR FT QVLLRKLSLRHSPDKRASSSPSGS" FT misc_feature order(240235..240303,240331..240390,240409..240465, FT 240493..240561,240580..240648,240736..240795, FT 240886..240954,240997..241065,241102..241155) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 21-43, 53-72, 79-97, 107-129, FT 136-158, 188-207, 238-260, 275-297 and 310-327" FT misc_feature 240310..241177 FT /note="Branched-chain amino acid transport system / FT permease component Score = 94.8 E-value = 1.2e-25" FT CDS 241271..242053 FT /transl_table=11 FT /locus_tag="TW203" FT /product="putative branched chain amino acid ABC FT transporter ATP-binding subunit" FT /note="Similar to Escherichia coli high-affinity FT branched-chain amino acid transport ATP-binding protein FT LivG or b3455 or z4825 or ecs4302 SWALL:LIVG_ECOLI FT (SWALL:P22730) (255 aa) fasta scores: E(): 4.7e-36, 47.43% FT id in 253 aa" FT /db_xref="GOA:Q83I81" FT /db_xref="HSSP:1JI0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83I81" FT /protein_id="CAD66880.1" FT /translation="MQDALLQSEHLLDVRDLVVRFGGIVALDGVSFSVGRGEILALIGP FT NGAGKTTLFNVITGVYRPTSGDVSLESVSLKSVKRYRIARMGIARTFQNIRLFGGMTVL FT ENVAVGLGVHHKTHILGALFRTPRHCREEREIVERGLEILDMVGIAQDAYKLAGSLSYG FT SQRRLEIARALACQPKLLCLDEPAAGFNPAEKNQLVELILKIRDAGYSILLIEHDMKLI FT FDVADRVVVLDFGKKIADGLPDDVRNDPHVIAAYLGEG" FT misc_feature 241379..241973 FT /note="ABC transporter Score = 197.7 E-value = 1.3e-56" FT misc_feature 241400..241423 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 242078..242761 FT /transl_table=11 FT /locus_tag="TW204" FT /product="putative branched chain amino acid ABC FT transporter ATP-binding subunit" FT /note="Similar to Escherichia coli high-affinity FT branched-chain amino acid transport ATP-binding protein FT LivF or b3454 SWALL:LIVF_ECOLI (SWALL:P22731) (237 aa) FT fasta scores: E(): 1.4e-33, 52.42% id in 227 aa" FT /db_xref="GOA:Q83I80" FT /db_xref="HSSP:1JI0" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83I80" FT /protein_id="CAD66881.1" FT /translation="MNVSYGKIRVLYDISFTVNRGEIVSLIGSNGAGKTTLMRTISGLL FT NTSGKILFQGEDITKYAPYKRVLSGISQSPEGRGVFPGMTVRENLDMGAYARKDRKNIK FT DDFDRVYGLFPRLLERRDQLGGAMSGGEQQMLAIARAIMSRPKLLLLDEPSMGLAPQLI FT QQIFSIVREINRQGVTILMVEQNANQSLGISDHAMVLETGNITRTGTGKELLQDGSIRK FT AYLGV" FT misc_feature 242138..242684 FT /note="ABC transporter Score = 187.2 E-value = 1.9e-53" FT misc_feature 242159..242182 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 242459..242503 FT /note="PS00211 ABC transporters family signature." FT CDS 242928..243596 FT /transl_table=11 FT /gene="ftsY" FT /locus_tag="TW205" FT /product="putative SRP54-type protein" FT /note="Similar to Escherichia coli cell division protein FT FtsY or b3464 SWALL:FTSY_ECOLI (SWALL:P10121) (497 aa) FT fasta scores: E(): 4.8e-30, 47.32% id in 224 aa" FT /db_xref="GOA:Q83NQ2" FT /db_xref="HSSP:1FTS" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83NQ2" FT /protein_id="CAD66882.1" FT /translation="MREYLECRLSSFDPTLRLTNHPSVILIVGVNGVGKTATAGKLANL FT LHLRGKKVLLAAADTFRAAAVEQLSIWAQRAGVEIITPPKPRIDPASVAYSSVKKAIDD FT NYDVVVIDTAGRLHNKANLMAELERIARVTEKLVSIDEVLLVLDATTGQNGLTQARSFL FT EAVSVTGIVLSKTDSSAKAGFIFQVQESTGVPVKLIGTGEAIDDIAGFAPYAFVAQIFG FT " FT misc_feature 242985..243591 FT /note="SRP54-type protein, GTPase domain Score = 329.8 FT E-value = 2.2e-96" FT misc_feature 243012..243035 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 243510..243551 FT /note="PS00300 SRP54-type proteins GTP-binding domain FT signature." FT CDS 243756..244064 FT /transl_table=11 FT /gene="rpsJ" FT /locus_tag="TW206" FT /product="30S ribosomal protein S10" FT /note="Similar to Mycobacterium tuberculosis 30s ribosomal FT protein S10 RpsJ or RpsX or Rv0700 or mt0727 or mtcy210.19 FT SWALL:RS10_MYCTU (SWALL:P95048) (101 aa) fasta scores: E(): FT 7.7e-28, 70.29% id in 101 aa" FT /db_xref="GOA:Q83I79" FT /db_xref="InterPro:IPR018268" FT /db_xref="UniProtKB/Swiss-Prot:Q83I79" FT /protein_id="CAD66883.1" FT /translation="MEEQKIRIRLKSYSHEIIDVSAKKIVDTVTRAGATIVGPVPLPTK FT KSVVCVIRSPHRHKDSREHFEMRTHKRLINVVDLTPRAVDALMRLDLSSEVNVEIKL" FT misc_feature 243768..244053 FT /note="Ribosomal protein S10p/S20e Score = 176.1 E-value = FT 4e-50" FT misc_feature 243840..243887 FT /note="PS00361 Ribosomal protein S10 signature." FT CDS 244074..244706 FT /transl_table=11 FT /gene="rplC" FT /locus_tag="TW207" FT /product="50S ribosomal protein L3" FT /note="Similar to Escherichia coli 50s ribosomal protein L3 FT RplC or b3320 or z4691 or ecs4185 SWALL:RL3_ECOLI FT (SWALL:P02386) (209 aa) fasta scores: E(): 2.1e-32, 49.26% FT id in 205 aa" FT /db_xref="GOA:Q83I78" FT /db_xref="InterPro:IPR019926" FT /db_xref="UniProtKB/Swiss-Prot:Q83I78" FT /protein_id="CAD66884.1" FT /translation="MARALLGTKVGMTQIWSGRRVVPVTAVAVTTNVVSQVKAPEKDGY FT SRLQIATGAIDPRRVNRPRKGHFAKAGLTPRRFIREVDSEGSLGDEFGPEIFQEGQLVD FT VVGKSKGKGFSGTMKRHNFQGVSATHGSHRNHRKPGSVGASSTPSRVFKGTRMAGRLGS FT SRVTVHNLRLVKIDSENGLLLVEGAVPGSSGSPVIIRDAVKGVPIVS" FT misc_feature 244098..244671 FT /note="Ribosomal protein L3 Score = 213.6 E-value = FT 2.2e-61" FT misc_feature 244362..244433 FT /note="PS00474 Ribosomal protein L3 signature." FT CDS 244696..245442 FT /transl_table=11 FT /gene="rplD" FT /locus_tag="TW208" FT /product="50s ribosomal protein L4" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L4 RplD SWALL:RL4_BACST (SWALL:P28601) (207 aa) FT fasta scores: E(): 6.1e-28, 41.62% id in 197 aa" FT /db_xref="GOA:Q83I77" FT /db_xref="InterPro:IPR013005" FT /db_xref="UniProtKB/Swiss-Prot:Q83I77" FT /protein_id="CAD66885.1" FT /translation="MSPSATVFDIGGNAVGTLQLVGHLFDSDPNLHLIHQVVVAQQAAF FT RQGTHKTKSRAEVSGSGRKPFRQKGTGNARCGSTRAPQMRGGGVVHGPVPRSYVHRTPK FT KMIKAALAGCLTNRARAGRVHIVDSFGDTPSVADALTLFQITGLSSKLLVVAQASDSVA FT YRSVRNIPGVRLVHVGQLNSYDVLRSDDVLFTRGAYNVFVGPSGDLAFSEDRDNPGTSL FT PKSPTPEDSSDATKARSSRHDDRTGA" FT misc_feature 244741..245308 FT /note="Ribosomal protein L4/L1 family Score = 159.9 E-value FT = 3e-45" FT CDS 245439..245750 FT /transl_table=11 FT /gene="rplW" FT /locus_tag="TW209" FT /product="50s ribosomal protein L23" FT /note="Similar to Mycobacterium bovis 50s ribosomal protein FT L23 RplW SWALL:RL23_MYCBO (SWALL:O06046) (100 aa) fasta FT scores: E(): 8.8e-19, 69.31% id in 88 aa, and to Thermus FT thermophilus ribosomal protein L23 SWALL:Q9RA57 FT (EMBL:AF094532) (96 aa) fasta scores: E(): 1.4e-11, 51.76% FT id in 85 aa" FT /db_xref="GOA:Q83I76" FT /db_xref="HSSP:1N88" FT /db_xref="InterPro:IPR001014" FT /db_xref="UniProtKB/TrEMBL:Q83I76" FT /protein_id="CAD66886.1" FT /translation="MMRRYSSSVINNKHVHDVILGPAISEKTYGLLEDSKYTFLVDPKS FT NKTEIKLAVEKIFGVKVSSVNTMNRRGKLQRTRKGIGRRKDRKRAVVTLKSGTIDLFT" FT misc_feature 245484..245745 FT /note="Ribosomal protein L23 Score = 107.4 E-value = FT 1.9e-29" FT misc_feature 245700..245744 FT /note="This hit extended beyond the end of the feature by 1 FT aa and was clipped." FT /note="PS00050 Ribosomal protein L23 signature." FT CDS 245758..246591 FT /transl_table=11 FT /gene="rplB" FT /locus_tag="TW210" FT /product="50s ribosomal protein l2" FT /note="Similar to Escherichia coli 50s ribosomal protein l2 FT RplB or b3317 or z4688 or ecs4182 SWALL:RL2_ECOLI FT (SWALL:P02387) (272 aa) fasta scores: E(): 6e-60, 56.93% id FT in 274 aa" FT /db_xref="GOA:Q83I75" FT /db_xref="HSSP:1RL2" FT /db_xref="InterPro:IPR014722" FT /db_xref="UniProtKB/Swiss-Prot:Q83I75" FT /protein_id="CAD66887.1" FT /translation="MAVRKSNPLTPARRGMSFSDFAEITRATPHKSLLSKLSKTGGRNN FT HGRITARHIGGGHKRRYRLVDFRRSDKDGVKAKVAHIEYDPNRTARIALLHFLDGAKRY FT ILAPSGLKQGDVVESGSSADIRPGNSLCIRDIPVGTILHAVELRPGQGAKLARSAGSSV FT RLSAKDGDFAILKLPSGEIRMVSLSCRATIGEVGNGQRLNVSLGKAGRSRWCGVRPSVR FT GVAMNPVDHPHGGGEGKTSGGRHPVSPWGRPEGKTRRANKPSDRFIIRRKSRKRR" FT misc_feature 245881..246112 FT /note="Ribosomal Proteins L2, RNA binding domain Score = FT 162.1 E-value = 6.5e-46" FT misc_feature 246130..246514 FT /note="Ribosomal Proteins L2, C-terminal domain Score = FT 286.9 E-value = 1.8e-83" FT misc_feature 246412..246447 FT /note="PS00467 Ribosomal protein L2 signature." FT CDS 246596..246877 FT /transl_table=11 FT /gene="rpsS" FT /locus_tag="TW211" FT /product="30s ribosomal protein s19" FT /note="Similar to Escherichia coli 30s ribosomal protein FT S19 RpsS or b3316 or z4687 or ecs4181 SWALL:RS19_ECOLI FT (SWALL:P02375) (91 aa) fasta scores: E(): 6.9e-26, 67.39% FT id in 92 aa" FT /db_xref="GOA:Q83I74" FT /db_xref="HSSP:1FKA" FT /db_xref="InterPro:IPR005732" FT /db_xref="UniProtKB/Swiss-Prot:Q83I74" FT /protein_id="CAD66888.1" FT /translation="MPRSLKKGPFVDMHLLKKVRAGNESKDRNMIKTWSRRSMIIPEML FT GHTIAVHDGRRHIPVFITESMVGHKLGEFAPTRTYRGHVKDDRKARRR" FT misc_feature 246602..246842 FT /note="Ribosomal protein S19 Score = 176.2 E-value = FT 3.8e-50" FT misc_feature 246752..246826 FT /note="PS00323 Ribosomal protein S19 signature." FT CDS 246877..247236 FT /transl_table=11 FT /gene="rplV" FT /locus_tag="TW212" FT /product="50s ribosomal protein l22" FT /note="Similar to Escherichia coli 50s ribosomal protein FT L22 RplV or EryB or b3315 or z4686 or ecs4180 or stm3435 or FT sty4363 SWALL:RL22_ECOLI (SWALL:P02423) (110 aa) fasta FT scores: E(): 2.2e-13, 45.37% id in 108 aa" FT /db_xref="GOA:Q83I73" FT /db_xref="HSSP:1BXE" FT /db_xref="InterPro:IPR005727" FT /db_xref="UniProtKB/Swiss-Prot:Q83I73" FT /protein_id="CAD66889.1" FT /translation="MSEEKDTPLEAFASLKHSGVTPQKVRRIVDLIRGRSVDEALAILR FT FSPHSASGILYKLIVSAQANYANLLGRDDDLFVSSVYVDEGKTYKRGRPRARGSSSRIL FT KRGSHVTVTLSKEVR" FT misc_feature 246913..247222 FT /note="Ribosomal protein L22p/L17e Score = 127.3 E-value = FT 1.9e-35" FT misc_feature 247144..247218 FT /note="PS00464 Ribosomal protein L22 signature." FT CDS 247239..247901 FT /transl_table=11 FT /gene="rpsC" FT /locus_tag="TW213" FT /product="30s ribosomal protein S3" FT /note="Similar to Escherichia coli 30s ribosomal protein S3 FT RpsC or b3314 or z4685 or ecs4179 or stm3434 or sty4364 FT SWALL:RS3_ECOLI (SWALL:P02352) (232 aa) fasta scores: E(): FT 7.2e-36, 50.72% id in 207 aa" FT /db_xref="GOA:Q83I72" FT /db_xref="InterPro:IPR008282" FT /db_xref="UniProtKB/Swiss-Prot:Q83I72" FT /protein_id="CAD66890.1" FT /translation="MGQKINPYGLRLGITTDHVSHWYSDSTRPGQRYADYVSEDIKIRS FT YLTKTLDRAGIARIEIERTRDRIRVDIYTARPGIVIGRRGAEADRYRLELEKITSKQVQ FT LNILEVKNPETTARLVAQGIAEQLAARVAFRRAMRKGLQSATSAGVRGIRIRLAGRLGG FT AEISRSEFYIEGQVPLQTLRASIDYGFYEARTPYGHIGVKVWIYKKPSVRGRTEGGG" FT misc_feature 247239..247434 FT /note="Ribosomal protein S3, N-terminal domain Score = 98.0 FT E-value = 1.3e-26" FT misc_feature 247443..247584 FT /note="KH domain Score = 20.6 E-value = 0.00091" FT misc_feature 247605..247854 FT /note="Ribosomal protein S3, C-terminal domain Score = FT 147.0 E-value = 2.3e-41" FT misc_feature 247737..247841 FT /note="PS00548 Ribosomal protein S3 signature." FT CDS 247898..248329 FT /transl_table=11 FT /gene="rplP" FT /locus_tag="TW214" FT /product="50s ribosomal protein L16" FT /note="Similar to Bacillus subtilis 50s ribosomal protein FT L16 RplP SWALL:RL16_BACSU (SWALL:P14577) (144 aa) fasta FT scores: E(): 2.4e-32, 56.61% id in 136 aa" FT /db_xref="GOA:Q83I71" FT /db_xref="InterPro:IPR000114" FT /db_xref="UniProtKB/Swiss-Prot:Q83I71" FT /protein_id="CAD66891.1" FT /translation="MMLIPKKVKFRKQHRPNRKGMSGCGTRIVFGDYGIQALSRAYVTN FT RQVESARIAMTRHIRRGGRVWINIYPDRPLTKKPAETRMGSGKGSPEYWVANIRPGRIM FT FEVSGVSESLAKEALMRAIHKLPLRARIVERQEFDDAGL" FT misc_feature 247901..248294 FT /note="Ribosomal protein L16 Score = 246.8 E-value = FT 2.1e-71" FT misc_feature 248144..248179 FT /note="PS00701 Ribosomal protein L16 signature 2." FT CDS 248316..248555 FT /transl_table=11 FT /gene="rpmC" FT /locus_tag="TW215" FT /product="50s ribosomal protein L29" FT /note="Similar to Escherichia coli 50s ribosomal protein FT L29 RpmC or b3312 or z4683 or ecs4177 SWALL:RL29_ECOLI FT (SWALL:P02429) (63 aa) fasta scores: E(): 0.0011, 40% id in FT 60 aa, and to Streptomyces coelicolor 50s ribosomal protein FT L29 RpmC or SCO4710 or SCD31.35 SWALL:RL29_STRCO FT (SWALL:Q9L0D2) (74 aa) fasta scores: E(): 9.1e-12, 54.93% FT id in 71 aa" FT /db_xref="GOA:Q83I70" FT /db_xref="InterPro:IPR018254" FT /db_xref="UniProtKB/Swiss-Prot:Q83I70" FT /protein_id="CAD66892.1" FT /translation="MLGSKGLSPTDLRGMTDGHLRVELKNAKEEVFKLRFQSATGQLAH FT NARLRAVRRDIARIYTVMRERDIGIRSVQEEVSQ" FT misc_feature 248340..248526 FT /note="Ribosomal L29 protein Score = 75.4 E-value = FT 8.4e-20" FT CDS 248552..248812 FT /transl_table=11 FT /gene="rpsQ" FT /locus_tag="TW216" FT /product="30S ribosomal protein S17" FT /note="Similar to Escherichia coli 30s ribosomal protein FT S17 RpsQ or NeaA or b3311 or z4681 or ecs4176 FT SWALL:RS17_ECOLI (SWALL:P02373) (83 aa) fasta scores: E(): FT 2.3e-12, 49.35% id in 77 aa" FT /db_xref="GOA:Q83I69" FT /db_xref="HSSP:1RIP" FT /db_xref="InterPro:IPR019979" FT /db_xref="UniProtKB/Swiss-Prot:Q83I69" FT /protein_id="CAD66893.1" FT /translation="MSQQRGYRKSRRGYVTSNSMDKTIVVKIEDRVKHALYGKVIRKTS FT KVKAHDQGSIAGVGDLVLISETRPISATKRWRLVQILEKAK" FT misc_feature 248588..248792 FT /note="Ribosomal protein S17 Score = 113.0 E-value = 4e-31" FT misc_feature 248726..248764 FT /note="PS00056 Ribosomal protein S17 signature." FT CDS 248910..249281 FT /transl_table=11 FT /gene="rplN" FT /locus_tag="TW217" FT /product="50s ribosomal protein L14" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L14 RplN SWALL:RL14_BACST (SWALL:P04450) (122 aa) FT fasta scores: E(): 1e-30, 72.35% id in 123 aa" FT /db_xref="GOA:Q83I68" FT /db_xref="HSSP:1WHI" FT /db_xref="InterPro:IPR019972" FT /db_xref="UniProtKB/Swiss-Prot:Q83I68" FT /protein_id="CAD66894.1" FT /translation="MIQQESRLKVADNTGAKSLSVIRVLGGSNRRFGSLGDVVVASVKD FT AVPGSSAVKKGDVVKAVIVRSTKEVRRTDGSYIRFDDNAAVILRPDNDPRGTRIFGPVA FT RELRDRKFTRIISLAPEVV" FT misc_feature 248910..249276 FT /note="Ribosomal protein L14p/L23e Score = 260.6 E-value = FT 1.4e-75" FT misc_feature 249090..249170 FT /note="PS00049 Ribosomal protein L14 signature." FT CDS 249284..249625 FT /transl_table=11 FT /gene="rplX" FT /locus_tag="TW218" FT /product="50S ribosomal protein L24" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L24 RplX SWALL:RL24_BACST (SWALL:P04455) (103 aa) FT fasta scores: E(): 1.9e-11, 42.85% id in 112 aa" FT /db_xref="GOA:Q83I67" FT /db_xref="InterPro:IPR005825" FT /db_xref="UniProtKB/Swiss-Prot:Q83I67" FT /protein_id="CAD66895.1" FT /translation="MSVKIRKGDLVQVITGSKTGGKKGKQGRVLAVSGDRVWVEGVNLT FT TRHRKRVTNDKGTSSGGLEKRESPMHISNVALVDPETGAPTKVGFLVKTSGDKTVRVRF FT AKKSGKELT" FT misc_feature 249302..249382 FT /note="PS00052 Ribosomal protein S7 signature." FT CDS 249622..250173 FT /transl_table=11 FT /gene="rplE" FT /locus_tag="TW219" FT /product="50S ribosomal protein L5" FT /note="Similar to Escherichia coli 50s ribosomal protein L5 FT RplE or b3308 or z4678 or ecs4173 SWALL:RL5_ECOLI FT (SWALL:P02389) (178 aa) fasta scores: E(): 1.3e-37, 54.23% FT id in 177 aa" FT /db_xref="GOA:Q83I66" FT /db_xref="HSSP:1IQ4" FT /db_xref="InterPro:IPR002132" FT /db_xref="UniProtKB/Swiss-Prot:Q83I66" FT /protein_id="CAD66896.1" FT /translation="MTCYTPRLLTRYREEIVPVLMSRFDINNVHQVPSITKIVVNSGVG FT DAARDSKIIEGAVSDITLITGQKPRINRAKQSIAKFKLREGQAVGVTATLRGRRMWEFL FT DRLLTLALPRIRDFRGISDKQFDGHGNYTFGLSEQGIFHEIDQDKIDRVRGMDITVVTT FT SSSDDMARALLGELGFPFKK" FT misc_feature 249703..249871 FT /note="Ribosomal protein L5 Score = 98.0 E-value = 1.3e-26" FT misc_feature 249883..250165 FT /note="ribosomal L5P family C-terminus Score = 177.5 FT E-value = 1.5e-50" FT CDS 250203..250601 FT /transl_table=11 FT /gene="rpsH" FT /locus_tag="TW220" FT /product="30S ribosomal protein S8" FT /note="Similar to Bacillus stearothermophilus 30s ribosomal FT protein S8 RpsH SWALL:RS8_BACST (SWALL:P56209) (130 aa) FT fasta scores: E(): 2.1e-25, 57.81% id in 128 aa" FT /db_xref="GOA:Q83I65" FT /db_xref="HSSP:1SEI" FT /db_xref="InterPro:IPR000630" FT /db_xref="UniProtKB/Swiss-Prot:Q83I65" FT /protein_id="CAD66897.1" FT /translation="MTMTDPLSDMFSRIRNANQVLHKKVTVPSSRLKVSIADLLKREGY FT ILDYSVIDEHPGQLLVIELKYGPDKSRALVGLKRVSKPGLRVYAKSSNLPEVFGGLGIA FT ILSTSSGLLTCSQARKKGVGGEVLAYAW" FT misc_feature 250215..250596 FT /note="Ribosomal protein S8 Score = 214.2 E-value = FT 1.4e-61" FT misc_feature 250506..250559 FT /note="PS00053 Ribosomal protein S8 signature." FT CDS 250595..251140 FT /transl_table=11 FT /gene="rplF" FT /locus_tag="TW221" FT /product="50S ribosomal protein L6" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L6 RplF SWALL:RL6_BACST (SWALL:P02391) (177 aa) FT fasta scores: E(): 1.3e-31, 54.8% id in 177 aa" FT /db_xref="GOA:Q83I64" FT /db_xref="HSSP:1C04" FT /db_xref="InterPro:IPR019906" FT /db_xref="UniProtKB/Swiss-Prot:Q83I64" FT /protein_id="CAD66898.1" FT /translation="MVDMSRVGKLPIEIPVGVEVCVNGRTVSITGPKGSLYLDIAEQIG FT VSVSDGKVLVSRSDDSRTARALHGLTRALIANNVHGVLHGYTKTLEIVGTGYRVSKKGE FT NLELALGFSHPVFVDPVPGVSFGVEGNSKIIVSGIDKQAVGEAAASIRKLSKPEPYKGK FT GIRYSDEIVRRKVGKAGK" FT misc_feature 250634..250847 FT /note="Ribosomal protein L6 Score = 63.0 E-value = 4.5e-16" FT misc_feature 250871..251096 FT /note="Ribosomal protein L6 Score = 85.9 E-value = 5.6e-23" FT misc_feature 251063..251089 FT /note="PS00525 Ribosomal protein L6 signature 1." FT CDS 251137..251496 FT /transl_table=11 FT /gene="rplR" FT /locus_tag="TW222" FT /product="50S ribosomal protein L18" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L18 RplR SWALL:RL18_BACST (SWALL:P09415) (120 aa) FT fasta scores: E(): 8.7e-20, 52.54% id in 118 aa" FT /db_xref="GOA:Q83I63" FT /db_xref="HSSP:1OVY" FT /db_xref="InterPro:IPR004389" FT /db_xref="UniProtKB/Swiss-Prot:Q83I63" FT /protein_id="CAD66899.1" FT /translation="MSLTSRASARKRRHVRLRKKISGTCDRPRLSVTRSNRHVFVQAVD FT DISGKTLVSASTMEKDIRALELGKTERALAVGKLVAQRALAVGVKSAVFDRGGCKYTGR FT VAAVAEGAREAGLQT" FT misc_feature 251149..251491 FT /note="Ribosomal L18p/L5e family Score = 162.3 E-value = FT 5.9e-46" FT CDS 251493..252353 FT /transl_table=11 FT /gene="rpsE" FT /locus_tag="TW223" FT /product="30s ribosomal protein S5" FT /note="Similar to Bacillus stearothermophilus 30s ribosomal FT protein S5 RpsE SWALL:RS5_BACST (SWALL:P02357) (166 aa) FT fasta scores: E(): 5.9e-26, 62.32% id in 146 aa. Has an FT unusually long N-terminal extension relative to homologues FT so may use a downstream alternative translational start FT site." FT /db_xref="GOA:Q83I62" FT /db_xref="HSSP:1PKP" FT /db_xref="InterPro:IPR018192" FT /db_xref="UniProtKB/Swiss-Prot:Q83I62" FT /protein_id="CAD66900.1" FT /translation="MIHDDDTVDLTDTLADAADSTRSAPDPAPVSDASPRGSSSGADVS FT DAARRQSGTVRQSGNDMVRQSGSELSDQSDTDISADSDTSASQGSARHSARGRHRDSRQ FT KGDSSSRGQFLERVVRINRVAKVVKGGRKFSFSALVVVGDGDGTVGVGYGKAREVPLAI FT SKGIESARKNFFTVPRVASTIPHPVQGEAASGVVLLRPAAPGTGVIAGGPVRAVLECAG FT VRDVLSKSLGSSNSINVVYATLDALKHLEDPASVARRRGLDYYHVVPKRIVRAVNSVGA FT SSDTA" FT misc_feature 251829..252027 FT /note="Ribosomal protein S5, N-terminal domain Score = FT 136.6 E-value = 3.2e-38" FT misc_feature 251883..251981 FT /note="PS00585 Ribosomal protein S5 signature." FT misc_feature 252054..252273 FT /note="Ribosomal protein S5, C-terminal domain Score = FT 126.0 E-value = 4.8e-35" FT CDS 252558..253001 FT /transl_table=11 FT /gene="rplO" FT /locus_tag="TW224" FT /product="50s ribosomal protein L15" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L15 RplO SWALL:RL15_BACST (SWALL:P04452) (146 aa) FT fasta scores: E(): 3.1e-15, 44.75% id in 143 aa" FT /db_xref="GOA:Q83I61" FT /db_xref="InterPro:IPR005749" FT /db_xref="UniProtKB/Swiss-Prot:Q83I61" FT /protein_id="CAD66901.1" FT /translation="MRLIKLHHLRPAPGSRRARIRVGRGEGSKGKTAGRGTKGTKARAP FT VRPGFAGGQIPLHMSIPKLKGFKNHKKVEYSVISIKRLCEAYPSGGVVTRDNVMSVIGK FT KRGFVKLLSDGEVTVKFDITVDKASAAAVEKITSAAGTVTQAR" FT misc_feature 252567..252861 FT /note="Ribosomal protein L15 amino terminal region Score = FT 123.2 E-value = 3.4e-34" FT misc_feature 252630..252653 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 252885..252978 FT /note="Ribosomal protein L15 Score = 29.2 E-value = 7e-06" FT CDS 253023..254348 FT /transl_table=11 FT /gene="secY" FT /locus_tag="TW225" FT /product="preprotein translocase SecY subunit" FT /note="Similar to Streptomyces griseus preprotein FT translocase SecY subunit SWALL:SECY_STRGR (SWALL:Q59916) FT (437 aa) fasta scores: E(): 2.9e-97, 57.52% id in 445 aa" FT /db_xref="GOA:Q83NQ1" FT /db_xref="InterPro:IPR002208" FT /db_xref="UniProtKB/TrEMBL:Q83NQ1" FT /protein_id="CAD66902.1" FT /translation="MFGVVRRMFSTTDLRRKLLFSVFIIVIFRLGSFIPSPYVNFTNVQ FT VCLAANSGATGIYELINLFSGGALLQLSVFALGVMPYITSSIIIQLLRVVVPRFEQLYK FT QGQEGQAKLIQYTRYLTIGLAVLQSTTLITVARSGALFAASNSPACSSLLTDDSWYSTI FT IIVIVMTAGTGLIMWLGELITERGIGNGMSILIFTSIAAGFPGVLVGVYQTRGFGMFST FT VVITSLVVMVGVVFVEQSQRRVPVQYAKRVVGRRILGGGSTYLPIKLNMAGVVPVIFAS FT AILRVPSIIAQFSQPAPGQPPAAWVVWINENFTTGNSPFYIALYFFMIVGFTYFYVAVT FT FNPTEIADNMKNYGGFISGIRPGVPTANYLSYIIKRITLPGSLYLGIVSLIPLIAFALF FT GLSADIPLGGTSVLIMVGVGLDTVKQIDAQMQQRHYRGLLTA" FT misc_feature 253023..253166 FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.891) with cleavage FT site probability 0.399 between residues 48 and 49" FT misc_feature order(253077..253145,253242..253310,253368..253436, FT 253494..253562,253581..253649,253662..253730, FT 253791..253859,253980..254048,254163..254231) FT /note="9 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 19-41, 74-96, 116-138, FT 158-180, 187-209, 214-236, 257-279, 320-342 and 381-403" FT misc_feature 253239..253298 FT /note="PS00755 Protein secY signature 1." FT misc_feature 253239..254295 FT /note="eubacterial secY protein Score = 548.2 E-value = FT 3.8e-162" FT misc_feature 253554..253610 FT /note="PS00756 Protein secY signature 2." FT CDS 254348..254908 FT /transl_table=11 FT /gene="adk" FT /locus_tag="TW226" FT /product="adenylate kinase" FT /note="Similar to Xanthomonas campestris adenylate kinase FT Adk or Xcc3291 SWALL:AAM42561 (EMBL:AE012446) (187 aa) FT fasta scores: E(): 3.3e-21, 37.96% id in 187 aa, and to FT Homo sapiens adenylate kinase isoenzyme 1 Ak1 FT SWALL:KAD1_HUMAN (SWALL:P00568) (194 aa) fasta scores: E(): FT 3.7e-14, 32.78% id in 183 aa" FT /db_xref="GOA:Q83I60" FT /db_xref="InterPro:IPR000850" FT /db_xref="UniProtKB/Swiss-Prot:Q83I60" FT /protein_id="CAD66903.1" FT /translation="MRAIMVGPPGSGKGTQCGLIQSRLGISVIATGDVFRERMKTDMAL FT RDIVSSGGYVSDSTTNRIVEDCLDKEDVSSGFVLDGYPRTLQQLDFLEGFLKRRALTLD FT AVFSLEVATDLLIERLRARSKESGRTDDRDSVIARRLEIYTEMTLPIIDACEEKGLLHR FT IDASKGIEEVFQSIKDVFDRVTI" FT misc_feature 254360..254825 FT /note="Adenylate kinase Score = 139.0 E-value = 5.8e-39" FT misc_feature 254576..254611 FT /note="PS00113 Adenylate kinase signature." FT CDS 254911..255774 FT /transl_table=11 FT /locus_tag="TW227" FT /product="putative aminotransferase" FT /note="Similar to Bacillus licheniformis D-alanine FT aminotransferase Dat SWALL:DAAA_BACLI (SWALL:P54692) (283 FT aa) fasta scores: E(): 5.1e-11, 29.91% id in 244 aa" FT /db_xref="GOA:Q83I59" FT /db_xref="HSSP:1A3G" FT /db_xref="InterPro:IPR001544" FT /db_xref="UniProtKB/TrEMBL:Q83I59" FT /protein_id="CAD66904.1" FT /translation="MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFET FT IGILSGRILNLDEHLERMCTSANRLGLRSIEPDRWRSLILQSAKKIADQERAGLRVVYA FT RNSNRSYLAWIAAFAVRDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYAVNM FT HALEVAQARGADDAIFLSEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLF FT MLLEAEGKKTLETSVATEALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNEL FT LARSAV" FT misc_feature 254962..255757 FT /note="Aminotransferase class IV Score = 23.8 E-value = FT 2.5e-12" FT CDS 255844..256065 FT /transl_table=11 FT /gene="infA" FT /locus_tag="TW228" FT /product="translation initiation factor IF-1" FT /note="Similar to Escherichia coli translation initiation FT factor IF-1 InfA or b0884 or z1228 or ecs0969 or stm0953 or FT sty0951 SWALL:IF1_ECOLI (SWALL:P02998) (71 aa) fasta FT scores: E(): 3.7e-16, 65.27% id in 72 aa" FT /db_xref="GOA:Q83I58" FT /db_xref="InterPro:IPR004368" FT /db_xref="UniProtKB/Swiss-Prot:Q83I58" FT /protein_id="CAD66905.1" FT /translation="MAKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHY FT IRILPEDRVVVELSPYDLARGRIVYRYK" FT misc_feature 255850..256060 FT /note="S1 RNA binding domain Score = 34.6 E-value = FT 1.6e-07" FT misc_feature 256021..256050 FT /note="PS00215 Mitochondrial energy transfer proteins FT signature." FT CDS 256068..256187 FT /transl_table=11 FT /gene="rpmJ" FT /locus_tag="TW229" FT /product="50S ribosomal protein L36" FT /note="Similar to Thermus thermophilus 50s ribosomal FT protein L36 RpmJ or Rpl36 SWALL:RL36_THETH (SWALL:P80256) FT (37 aa) fasta scores: E(): 3.8e-10, 70.27% id in 37 aa" FT /db_xref="GOA:Q83I57" FT /db_xref="HSSP:1DFE" FT /db_xref="InterPro:IPR000473" FT /db_xref="UniProtKB/Swiss-Prot:Q83I57" FT /protein_id="CAD66906.1" FT /translation="MLVKVKPSVKKICGVCKVIRRNGRVAVLCSNPRHKQRQG" FT misc_feature 256074..256182 FT /note="Ribosomal protein L36 Score = 62.1 E-value = FT 8.6e-16" FT misc_feature 256104..256181 FT /note="PS00828 Ribosomal protein L36 signature." FT CDS 256222..256596 FT /transl_table=11 FT /gene="rpsM" FT /locus_tag="TW230" FT /product="30S ribosomal protein S13" FT /note="Similar to Synechococcus sp. 30s ribosomal protein FT S13 RpsM or Rps13 SWALL:RS13_SYNP6 (SWALL:O24708) (125 aa) FT fasta scores: E(): 6.5e-27, 61.78% id in 123 aa" FT /db_xref="GOA:P66398" FT /db_xref="InterPro:IPR018269" FT /db_xref="UniProtKB/Swiss-Prot:P66398" FT /protein_id="CAD66907.1" FT /translation="MARVAGVDIPGNKRVEIGLTYICGIGPTRSRHALTAAGISFDTRV FT KDLTDDQLVALRAHIQNSYRIEGDLRREVASDIRRKVEIGCYQGLRHRRGLPVNGQRTR FT TNARSSKGPRRTVAGKKKAR" FT misc_feature 256228..256546 FT /note="Ribosomal protein S13/S18 Score = 166.5 E-value = FT 3.1e-47" FT misc_feature 256309..256341 FT /note="PS00639 Eukaryotic thiol (cysteine) proteases FT histidine active site." FT CDS 256600..256992 FT /transl_table=11 FT /gene="rpsK" FT /locus_tag="TW231" FT /product="30S ribosomal protein S11" FT /note="Similar to Escherichia coli 30s ribosomal protein FT S11 RpsK or b3297 or z4667 or ecs4162 SWALL:RS11_ECOLI FT (SWALL:P02366) (128 aa) fasta scores: E(): 7.1e-26, 56.69% FT id in 127 aa" FT /db_xref="GOA:P66366" FT /db_xref="InterPro:IPR018102" FT /db_xref="UniProtKB/Swiss-Prot:P66366" FT /protein_id="CAD66908.1" FT /translation="MSKQAQSRSRKKARKNIPAGLAHIKSTFNNTIVTITDLSGNVIGW FT SSSGAVGFKGSRKSTPYAAQMAADAAARSAQEHGVKKVDVFVKGPGSGRETAIRSLQTA FT GLEIGSISDTTPLAFNGCRPPKKRLV" FT misc_feature 256657..256984 FT /note="Ribosomal protein S11 Score = 226.0 E-value = FT 3.8e-65" FT CDS 257011..257994 FT /transl_table=11 FT /gene="rpoA" FT /locus_tag="TW232" FT /product="DNA-directed RNA polymerase alpha chain" FT /EC_number="2.7.7.6" FT /note="Similar to Streptomyces coelicolor DNA-directed RNA FT polymerase alpha chain RpoA or SCO4729 or SC6G4.07 FT SWALL:RPOA_STRCO (SWALL:P72404) (340 aa) fasta scores: E(): FT 9.7e-75, 63.91% id in 327 aa" FT /db_xref="GOA:Q820D8" FT /db_xref="HSSP:1HQM" FT /db_xref="InterPro:IPR011773" FT /db_xref="UniProtKB/Swiss-Prot:Q820D8" FT /protein_id="CAD66909.1" FT /translation="MLIAHRPTLIEKKVSDIRSRFIIEPLEPGFGYTLGNSLRRTLLSS FT IPGAAVTSINIQGVMHEFSTIPGVKEDVTEIVLNVKRLVISSEIDEPFTVRLYKTGEGE FT VLAKDIEVPTGIEIGNGDLVIATLAKDAVFDMQLTIERGRGYVSAEQNRNDGMSLAGHI FT PVDSIYSPVHKVTYRVEATRAGERTDFDRLIIDVETKPSILPRDAVASAGKTLCELFGL FT ARELNSQAEGVEFGVDSMIPESDEDLRIPIEDLGLSVRSYNCLKREGVNYVSELLGFSE FT QELLDIRNFGQKSADEVQEKLAELGHSLKGSVPGFDGSYFDPNYGS" FT misc_feature 257062..257668 FT /note="Bacterial RNA polymerase, alpha chain, N terminal FT domain Score = 367.9 E-value = 7.6e-108" FT misc_feature 257632..257655 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature 257719..257920 FT /note="Bacterial RNA polymerase, alpha chain C terminal FT domain Score = 115.3 E-value = 8.3e-32" FT CDS 258010..258549 FT /transl_table=11 FT /gene="rplQ" FT /locus_tag="TW233" FT /product="50S ribosomal protein L17" FT /note="Similar to Bacillus stearothermophilus 50s ribosomal FT protein L17 RplQ SWALL:RL17_BACST (SWALL:P07843) (119 aa) FT fasta scores: E(): 3.8e-13, 47.7% id in 109 aa" FT /db_xref="GOA:Q83I55" FT /db_xref="HSSP:1GD8" FT /db_xref="InterPro:IPR000456" FT /db_xref="UniProtKB/Swiss-Prot:Q83I55" FT /protein_id="CAD66910.1" FT /translation="MPKPSRGPRMCSGPDHERLVLANMSASLFLNKKLRTTEARAKRLR FT PFAEKLVTLSKRGGLHSRRRALSILRNKAALHELFTNIAPLVEDRNGGYTRITKVGFRS FT GDGAPMALIELILEPVSARTRGTDTLPDTVIDTGPDSAPDPVPGSEPGSAAGDLPDADT FT APADPGESSSNQRVIR" FT misc_feature 258067..258355 FT /note="Ribosomal protein L17 Score = 130.0 E-value = 3e-36" FT CDS 258575..259378 FT /transl_table=11 FT /gene="truA" FT /locus_tag="TW234" FT /product="tRNA pseudouridine synthase A" FT /EC_number="4.2.1.70" FT /note="Similar to Escherichia coli tRNA pseudouridine FT synthase A TruA or HisT or AsuC or LeuK or b2318 FT SWALL:TRUA_ECOLI (SWALL:P07649) (270 aa) fasta scores: E(): FT 5.1e-18, 32.27% id in 251 aa, and to Streptomyces FT coelicolor tRNA pseudouridine synthase A TruA or SCO4731 or FT SC6G4.09 SWALL:TRUA_STRCO (SWALL:O86776) (284 aa) fasta FT scores: E(): 4.5e-34, 40.59% id in 271 aa" FT /db_xref="GOA:Q820Z2" FT /db_xref="InterPro:IPR020094" FT /db_xref="UniProtKB/Swiss-Prot:Q820Z2" FT /protein_id="CAD66911.1" FT /translation="MNKTRYRLDVAYDGANFCGWAPQPGLRTVGGLILDALRLICSEPP FT DIVIAARTDAGVHALQQVCHVDLISSPDPVWLLHRLRSLLKSETDLHILSAVKAPVNFH FT ARFSAIGRRYVYRVIDKRSSWYPQNRYFVYRVNAFLQDYRMRRAASGLIGLKDFGAFCK FT PRRMGSTVRHLRQFEVIRQPDGQIHFFLESDAFCHSMVRNLVGSLIEVGRGALTLQDLF FT CYTKIAKRTPKIPTLPPHALTLIGIDYPQEHLFECQNRKTRQKRT" FT misc_feature 258596..258896 FT /note="tRNA pseudouridine synthase Score = 83.2 E-value = FT 3.9e-22" FT misc_feature 259016..259322 FT /note="tRNA pseudouridine synthase Score = 42.0 E-value = FT 9.3e-10" FT CDS complement(259491..260606) FT /transl_table=11 FT /locus_tag="TW235" FT /product="putative MRP-family ATP-binding protein" FT /note="Similar to Mycobacterium tuberculosis Mrp protein FT homolog or rv1229c or mt1267 or mtci61.12c or mtv006.01C FT SWALL:MRP_MYCTU (SWALL:O33225) (381 aa) fasta scores: E(): FT 1.2e-45, 43.83% id in 365 aa" FT /db_xref="GOA:Q83I54" FT /db_xref="InterPro:IPR019591" FT /db_xref="UniProtKB/TrEMBL:Q83I54" FT /protein_id="CAD66912.1" FT /translation="MIEKKLYSAMEKVYDPELHIPITRLGMVKTITTDSKTVSILIHIT FT SPTCPAVDKIKQRVTDAASAVCPEHDIKIEIGVMSHQERQNLKEVLNLQKRSNPFKESK FT TRIIAVTSGKGGVGKSTIVSNLGVGLARMGFSVSVIDADVYGFSIPRMFGIDEDFIPQR FT ENGMIMPANKFGVKLISIGMFMRRRGAVAWRGPLLHRTINQFLCDVNFADPDILLIDMP FT PGTGDAAITIAQLLPNSEVLVITTPQIVAADVAIRSGQFALSVKQNIIGVVENMSSCPE FT SKLDIFGHGGGKFVAEFLDKQCKKESTAKDNRITNPHEAIDLITCIPLDVNIRKSGDEG FT VPLLVENKYEGSPGHTALKELYEKIALKLYG" FT misc_feature complement(260207..260291) FT /note="4Fe-4S iron sulfur cluster binding proteins, FT NifH/frxC family Score = 24.8 E-value = 3.1e-07" FT misc_feature complement(260247..260270) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT misc_feature complement(260381..260603) FT /note="Domain of unknown function DUF59 Score = 54.4 FT E-value = 1.8e-13" FT CDS complement(260614..261108) FT /transl_table=11 FT /locus_tag="TW236" FT /product="conserved hypothetical membrane protein" FT /note="Similar to Mycobacterium tuberculosis hypothetical FT protein Rv1231c or mtv006.03c or mt1269 SWALL:O86314 FT (EMBL:Z98260) (180 aa) fasta scores: E(): 1.4e-09, 39.25% FT id in 135 aa" FT /db_xref="InterPro:IPR010406" FT /db_xref="UniProtKB/TrEMBL:Q83I53" FT /protein_id="CAD66913.1" FT /translation="MKKSSKLHTPLLTSRMRLRYNPGVFEMRTERIALYMGTASFFIFF FT TTFCILWILWSNYAPNGLRFDSAEIGYPVLTLVLSVLAAYAAPLILLAEIRQWKRESLN FT MKQMREMADRNIASTEYLAREVADLRLSIAQLITDQQKNNNRLKRLEETEKTIQDFGND FT S" FT misc_feature complement(order(260833..260901,260944..261012)) FT /note="2 probable transmembrane helices predicted for FT Unknown_CDS by TMHMM2.0 at aa 33-55 and 70-92" FT CDS complement(261095..262342) FT /transl_table=11 FT /locus_tag="TW237" FT /product="conserved hypothetical protein" FT /note="Similar to Streptomyces coelicolor hypothetical FT protein SCO5154 or SCP8.17c SWALL:Q9FBK4 (EMBL:AL390975) FT (433 aa) fasta scores: E(): 6.5e-37, 38.06% id in 423 aa" FT /db_xref="InterPro:IPR006668" FT /db_xref="UniProtKB/TrEMBL:Q83I52" FT /protein_id="CAD66914.1" FT /translation="MSKSVYISRVCGSSVLGPTGDRLGKVKDVLGTPRLRKSPRIIGMV FT LEIVGKRYIFVSINRVTAIDNGYVATRGVINIQRFRRRSGEICLSQDIVGKKVSIGNNT FT TARAEDIEILADPAGEWYVGKIFVRTSGNRLFSRGNTCFMHWQDISGLDQVPDYISNPE FT IKAADLAADIVDMPSTDAARIVEDLPDERLADVLEEMEEPEQAKIIDALDDNRTADILE FT EMQPDDAVDLIGYMSNKRKEGLLQLMEPEEARKLRLLLGFAHNTAGGMMTSDFVIVSPD FT TTVAEALALIRRQEIAPALASTVCVALPPYDPPTGRFIGVVHFQALLRQPPYQKLSHII FT DTSIEPVLPTIDAEKVSRILATYNLLSLPVIDDRKRLLGIITIDDVLDYVLPKNWRKNE FT IDSTNNKENMVHNEKE" FT misc_feature complement(261172..261331) FT /note="CBS domain Score = 37.5 E-value = 2.2e-08" FT misc_feature complement(261349..261538) FT /note="CBS domain Score = 22.5 E-value = 0.00068" FT misc_feature complement(261544..261925) FT /note="MgtE intracellular domain Score = 58.7 E-value = FT 8.8e-15" FT CDS complement(262339..263508) FT /transl_table=11 FT /locus_tag="TW238" FT /product="Xaa-Pro aminopeptidase" FT /note="Similar to Streptomyces coelicolor Xaa-Pro FT aminopeptidase I PepP1 or SCO3970 or SCBAC25e3.07c FT SWALL:AMP1_STRCO (SWALL:Q05813) (490 aa) fasta scores: E(): FT 6.8e-55, 43.76% id in 409 aa, and to Escherichia coli FT Xaa-Pro aminopeptidase PepP or b2908 SWALL:AMPP_ECOLI FT (SWALL:P15034) (440 aa) fasta scores: E(): 1.9e-26, 35.63% FT id in 275 aa" FT /db_xref="GOA:Q83I51" FT /db_xref="HSSP:1A16" FT /db_xref="InterPro:IPR001131" FT /db_xref="UniProtKB/TrEMBL:Q83I51" FT /protein_id="CAD66915.1" FT /translation="MRCRANDTFYRYRPDSSFTWLTGWGCETTPGAVLVIYPDTKPVLF FT FKPPAGKKNDDFFTDSHNGTFWIGSRPSLQEIETLLGITCRDIKDFRCPTDNVLLCKTR FT GKDAEEINDLKVAISELRLLKDRWEITQLQKAVDATAQGFERVVKSINEAKSVTNGERV FT IEGAFYTSARSLGYETGYETIVAAGANACILHWSVNNGPINDGDLLLVDAGIELETLYT FT ADITRTVPISGKFTDVQAKAYEAVLEAADAAFDAAMPGQPFHKMHEAAMGVIRRHLSEW FT GICKASQNEFYRRYMIHGTGHHLGLDVHDCAFAKRENYRNGTLADGMVLTIEPGLYFHK FT NDLTVPKDFRGIGVRIEDNILIASDGPVNMSRDIPRARIDVEQWIQQAS" FT misc_feature complement(262365..263142) FT /note="metallopeptidase family M24 Score = 185.4 E-value = FT 6.3e-53" FT misc_feature complement(262579..262617) FT /note="PS00491 Aminopeptidase P and proline dipeptidase FT signature." FT CDS 263951..264562 FT /transl_table=11 FT /locus_tag="TW240" FT /product="hypothetical protein" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83I50" FT /protein_id="CAD66916.1" FT /translation="MGISEAHTPHKDIHLDVGLISAQIILLRNIFSTALGNIRACDSYA FT ASLIKRSESVQKCSKAPKEVFRAELVGAALSVQQLMSGRGEYVDLMSYFLISELMRDFH FT LLALSHLEVSEKYRIEELTCVDLKDKKKLSREIFRLLSRIARNDSTLSSMMSLWGRRIL FT GDVLLFIKLCIGQDHNNSRSLLSTLAGKHSERMRAIGLIA" FT CDS complement(264653..264874) FT /transl_table=11 FT /locus_tag="TW241" FT /product="conserved hypothetical protein" FT /note="Similar to Corynebacterium glutamicum hypothetical FT protein Cgl0772 SWALL:BAB98165 (EMBL:AP005276) (75 aa) FT fasta scores: E(): 0.0016, 34.72% id in 72 aa" FT /note="No significant database matches" FT /db_xref="UniProtKB/TrEMBL:Q83I49" FT /protein_id="CAD66917.1" FT /translation="MELKIGIANCIKEISFHVDITHEQLLQKVNDAVGNHGVLNLKDTG FT GEEIIIPGSALAYVWIVQEKKRVCGFVS" FT CDS 264900..267881 FT /transl_table=11 FT /locus_tag="TW242" FT /product="putative ATP-dependent DNA helicase subunit" FT /note="Similar to Streptomyces coelicolor putative FT ATP-dependent DNA helicase SCO5183 or 2SC3B6.07 FT SWALL:Q9FCK5 (EMBL:AL390968) (1159 aa) fasta scores: E(): FT 2.7e-07, 24.49% id in 1139 aa" FT /db_xref="GOA:Q83I48" FT /db_xref="InterPro:IPR003593" FT /db_xref="UniProtKB/TrEMBL:Q83I48" FT /protein_id="CAD66918.1" FT /translation="MFMDISECSLPDAIDSIARIPEGSRVSVIGPPGSGKTSLLLSLLE FT KYSESFEPEEVLVLAPGRLLANRLNGIALPALLKEKKVRSGRLVVTPASFAFRIVQNSM FT KGERPTLLSGADEDQVIAETIAQNCELFKSSYARSPNFRSRMRFFIEDLSRHGIDPAHL FT GKIDRWKTYAALIEKYRLARTSNNAFTAVEIIERAAQLASTGYLPYRVIMVDEAQELAA FT EHMRLFSALARRNITVILFGDPDKAVARSASPSIFLDFSEKLFVLKTVFRTPRNLHLLS FT QKICQGIGVTGSVLAHRQSFNSSILEGRVETVISSSRATSMADIARWFREKHLLEGIDW FT EDMALIIFQRSSAEVYSHFLERFGVPVQILGGGLNLSEKPIAGAILNAIELACFPDILT FT GKTLVKLLLSPIGGFDVFLMRKLTIELKRIAPKNIQVLNERLLWAFHAYRKLQTQDTDE FT VYRVFLASRIGRSLKKIFECLISLERLYREDNVSLPVLIWHVYSFLNLKSAVSKEPWQT FT SKVSHRVLEEVIALQKLADAVSKKDPLCSAGLILQKIINAEVPVDNLSIREKRGCVTIL FT TPASSVGYEYRAVVITDIQGSHKMDSTQLDPELALADINNIPFSRYLESKLAGRRHNLL FT RTLYQAVTRSTSDLLVSVIDSAETSPSWLFYAFFSDYPSCELSSLPLTLRGIVTQLRLD FT LERDPGNTEAASALRLLAKEGISQADPQNWYGYLSRTENKSYVMDSIKPSALDKFHTCP FT LGWFTDQLDCNRYPGNATEIGTIIHRCMQELTCDNRQPNLNEFLDYAYAKLREADFESR FT WVLEREKKRLVGIIRKLVDYLIDFDAHGGTLLASEKSFSFDLNVFKDRSIMISGQIDRL FT ERLSSGEIRIVDLKTGSSLLSKNDAESNLQLSAYQLAVEHLDIVYETLPSAMLIYPAVG FT TKKAAIRIKGPMDRDSKRVLKNTIRDLLLQNESFTLTAALEEHCESRTACKKLMVPHVS FT FSVK" FT misc_feature 264987..265010 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS 267878..270799 FT /transl_table=11 FT /locus_tag="TW243" FT /product="putative ATP-dependent DNA helicase subunit" FT /note="Similar to Streptomyces coelicolor putative FT ATP-dependent DNA helicase SCO5184 or 2SC3B6.08 FT SWALL:Q9FCK4 (EMBL:AL390968) (1222 aa) fasta scores: E(): FT 9.9e-16, 26.61% id in 1161 aa, and to Escherichia coli DNA FT helicase II UvrB or MutU or PdeB or Rad or Recl or b3813 FT SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): FT 2.8e-09, 24.25% id in 800 aa" FT /db_xref="GOA:Q83I47" FT /db_xref="HSSP:2PJR" FT /db_xref="InterPro:IPR014017" FT /db_xref="UniProtKB/TrEMBL:Q83I47" FT /protein_id="CAD66919.1" FT /translation="MNMSLRDSRHMCSILNLHAPTEEQRAIIESPLENALVIAGAGSGK FT TETLVLRLLWLIASGKLKPESIMGLTFTRKAAGELASRLQKSLAILNSYTGDVLSPEID FT VLTYNSFANSIYQDNALLLDHPVPYTAIEDSEAQLIARRLLVEHGLDEDEPSETIDNLA FT SSLIKLDDAIVDNLLDLGELNQFASEFIEFVGAFDAPVAKSDVFRAKRLIALSKLIPAL FT KDEKKLRGRISYSEQVAFALEVCRQTHVLAEFQEKIAYVVLDEYQDTSPIQVEFLKTIF FT GNRCRVLAVGDPRQAIFGFRGASVANIANFARDFVSNKQYELSISWRNDKNILDLANHI FT SPKIRPLHPRPEANDGSTSLEVYTDPEQEVHEGALWLNSVVEKGTAAVLTRTRSRLISV FT SRVLDEIGVSYTRADVNIFYEPGVVDILSCMRIISGVNENLSFLRLITGPRWQVGISDL FT HALRGYIAVGKKNLDRISLLEAVNRINIQKTPMSCEGKKRLEDFLEFFRKIKGLSFLSP FT LELAYLIEESLNLDIEVQMSHRGRENLDALYELIASFRGDNLSEMLAWFDSLEEEDAFR FT GPIKQSCPGQVELFTVHSAKGLEWDWVLLPFLDDFPAKSREKSGWLSKTGLLPFCLRLD FT RESLPEFYFHKCSDSKEYRAARRQYEDDVLQHQIREERKLLYVAVTRARQGLRISASAR FT QKPGQFLREISEFLQTDLPQAVHNNPKKRVGYWPLDSLGARRKRVKLAAAAVHNRSIEE FT SEESLKKEPLKALIAGMLKELDISVDKPEKRISATALSKKDPNVFLLPQPPIKNAWLGV FT AFHAWIENYYSTYSDMLFHENSADEYGISGPVFEQSQRFSPELDQLRHNFMQSEWSYKK FT PIAVELSLEWLIGDVIVPCTIDAVFFDGDRYTILDWKSGLSSNQYRIQLSLYRLAFAEW FT KGVNPDKVEAKIYFAADNRTIKVRPYTVDELGKMPGFLSDLFS" FT misc_feature 267935..269465 FT /note="UvrD/REP helicase Score = 189.1 E-value = 4.8e-54" FT misc_feature 267992..268015 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)." FT CDS complement(270823..271998) FT /transl_table=11 FT /locus_tag="TW244" FT /product="putative transferase" FT /note="Weakly similar to Escherichia coli macrolide FT 2'-phosphotransferase I MphA SWALL:Q47396 (EMBL:D16251) FT (301 aa) fasta scores: E(): 1.4e-07, 26.1% id in 226 aa" FT /db_xref="GOA:Q83I46" FT /db_xref="UniProtKB/TrEMBL:Q83I46" FT /protein_id="CAD66920.1" FT /translation="MIALSPMSMAAVAVATLPNLNVLQVARGTSDSHHVDSILRCDDNR FT WMLIRVPLSQNAKDKMARLVKNLRALSKGVRARLPFSIPNVLAYQPVKLSSGMNMTLIM FT DHPQGYALRDIKPGEGAATSIGWAIAAIHNLPSGLLISAGYTHKTAQDCRYEVIDFVDK FT ANATNMLPGSLKEKWETLVEDEDLWKFQTTVVKKNFSMDSFRFQDNQEGESSVCAILEW FT EDASIDDPAYDLHWLNQLSHESAESILKAYEAFSTTTHDRGCLERAKLYAELDIARILI FT DGVREEKHELIDMAKRLLLELDRTSAQEDTPKQAIHKAEGLLENAQNLSFEQQRSYEIQ FT SDDVNAYSDEETYKSDQVSDSGISENLRNIEEFLGSAKTNTEEENSEAKNE" FT misc_feature complement(271915..271998) FT /note="Signal peptide predicted for Unknown_CDS by SignalP FT 2.0 HMM (Signal peptide probabilty 0.931) with cleavage FT site probability 0.359 between residues 28 and 29" FT CDS 272079..273836 FT /transl_table=11 FT /locus_tag="TW245" FT /product="putative ATP-dependent DNA helicase" FT /note="Similar to Streptomyces coelicolor putative FT ATP-dependent DNA helicase SCO5188 or 2SC3B6.12 FT SWALL:Q9FCK0 (EMBL:AL390968) (785 aa) fasta scores: E(): FT 2.7e-40, 35.14% id in 606 aa, and to Escherichia coli DNA FT helicase II UvrD or MutU or PdeB or Rad or Recl or b3813 FT SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): FT 1.5e-19, 25.47% id in 636 aa" FT /db_xref="GOA:Q83I45" FT /db_xref="HSSP:1PJR" FT /db_xref="InterPro:IPR014016" FT /db_xref="UniProtKB/TrEMBL:Q83I45" FT /protein_id="CAD66921.1" FT /translation="MTIDVFSGLSDQQCDAVRTLRGPVKIIAGAGSGKTLTI |