EBI Dbfetch

ID   BX248344; SV 1; linear; genomic DNA; STD; PRO; 318050 BP.
XX
AC   BX248344;
XX
DT   10-JUN-2003 (Rel. 76, Created)
DT   14-JUL-2009 (Rel. 101, Last updated, Version 6)
XX
DE   Mycobacterium bovis subsp. bovis AF2122/97 complete genome; segment 11/14
XX
KW   complete genome.
XX
OS   Mycobacterium bovis AF2122/97
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
XX
RN   [1]
RX   DOI; 10.1073/pnas.1130426100
RX   PUBMED; 12788972.
RA   Garnier T., Eiglmeier K., Camus J.C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis";
RL   Proc. Natl. Acad. Sci. U.S.A. 100(13):7877-7882(2003).
XX
RN   [2]
RP   1-318050
RA   Garnier T.;
RT   ;
RL   Submitted (24-MAR-2003) to the EMBL/GenBank/DDBJ databases.
RL   Garnier T., Unite de Genetique Moleculaire Bacterienne Institut Pasteur
RL   28,rue du Dr Roux 75724 PARIS cedex 15, France. e-mail:tgarnier@pasteur.fr
RL   Submitted on behalf of the Mycobacterium bovis sequencing teams, TB
RL   Research Group, Veterinary Laboratories Agency Weybridge, Woodham Lane, New
RL   Haw,Addlestone, Surrey KT15 3NB, UK. Sanger Centre, Wellcome Trust Genome
RL   Campus, Hinxton,Cambridge CB10 1SA, UK. PT4 Annotation, Genopole, Institut
RL   Pasteur, 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France. Unite de
RL   Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur
RL   Roux, 75724 Paris Cedex 15, France.
XX
DR   EMBL-CON; BX248333.
DR   RFAM; RF00023; tmRNA.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..318050
FT                   /organism="Mycobacterium bovis AF2122/97"
FT                   /strain="AF2122/97"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:233413"
FT   CDS             complement(99..875)
FT                   /transl_table=11
FT                   /gene="Mb2882c"
FT                   /locus_tag="Mb2882c"
FT                   /product="PROBABLE SHORT-CHAIN TYPE
FT                   DEHYDROGENASE/REDUCTASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2882c, -, len: 258 aa. Equivalent to Rv2857c, len:
FT                   258 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 258 aa overlap). Probable short-chain
FT                   dehydrogenase/reductase (EC 1.-.-.-), highly similar to
FT                   various dehydrogenases e.g. O88068|SCI35.33c PROBABLE
FT                   DEHYDROGENASE (SDR FAMILY) from Streptomyces coelicolor
FT                   (260 aa), FASTA scores: opt: 1208, E(): 2e-68, (72.35%
FT                   identity in 253 aa overlap); Q9I376|PA1649 from Pseudomonas
FT                   aeruginosa PROBABLE SHORT-CHAIN DEHYDROGENASE (253 aa),
FT                   FASTA scores: opt: 569, E(): 2.1e-28, (39.2% identity in
FT                   255 aa overlap); Q9EX74|MLHA SDR-LIKE ENZYME from
FT                   Rhodococcus erythropolis (246 aa), FASTA scores: opt: 567,
FT                   E(): 2.8e-28, (41.15% identity in 248 aa overlap); etc.
FT                   Also similar to many Mycobacterium tuberculosis
FT                   dehydrogenases e.g. FABG3|Rv2002|MT2058|MTCY39.16c PUTATIVE
FT                   OXIDOREDUCTASE (260 aa), FASTA score: (38.3% identity in
FT                   248 aa overlap). BELONGS TO THE SHORT-CHAIN
FT                   DEHYDROGENASES/REDUCTASES (SDR) FAMILY."
FT                   /db_xref="GOA:Q7TXP6"
FT                   /db_xref="HSSP:1Q7B"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP6"
FT                   /protein_id="CAD96569.1"
FT                   /translation="MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVE
FT                   AGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRIDIAFNNAGISPPEDNLIENTE
FT                   LAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGG
FT                   VLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPD
FT                   EIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL"
FT   CDS             complement(872..2239)
FT                   /transl_table=11
FT                   /gene="aldC"
FT                   /locus_tag="Mb2883c"
FT                   /product="PROBABLE ALDEHYDE DEHYDROGENASE ALDC"
FT                   /EC_number="1.2.1.3"
FT                   /note="Mb2883c, aldC, len: 455 aa. Equivalent to Rv2858c,
FT                   len: 455 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 455 aa overlap). Probable aldC,
FT                   aldehyde dehydrogenase (EC 1.2.1.3), similar to many e.g.
FT                   O88069|SCI35.34c PUTATIVE ALDEHYDE DEHYDROGENASE from
FT                   Streptomyces coelicolor (483 aa), FASTA scores: opt: 1872,
FT                   E(): 6.4e-109, (64.5% identity in 448 aa overlap);
FT                   Q9FAB1|ALDH|BT-ALDH ALDEHYDE DEHYDROGENASE from Bacillus
FT                   thermoleovorans (497 aa), FASTA scores: opt: 1157, E():
FT                   2.1e-64, (44.3% identity in 458 aa overlap); O33455|CYMC
FT                   P-CUMIC ALDEHYDE DEHYDROGENASE from Pseudomonas putida (494
FT                   aa), FASTA scores: opt: 1149, E(): 6.5e-64, (43.15%
FT                   identity in 452 aa overlap);
FT                   P40047|DHA5_YEAST|ALD5|ALDH5|ALD3|YER073W ALDEHYDE
FT                   DEHYDROGENASE from Saccharomyces cerevisiae (Baker's yeast)
FT                   (519 aa), FASTA scores: opt: 1091, E(): 2.7e-60, (38.55%
FT                   identity in 459 aa overlap);
FT                   P80668|FEAB_ECOLI|PADA|MAOB|B1385 PHENYLACETALDEHYDE
FT                   DEHYDROGENASE (EC 1.2.1.39) from Escherichia coli strain
FT                   K12 (499 aa), FASTA scores: opt: 1074, E(): 3e-59, (42.2%
FT                   identity in 462 aa overlap); etc. Also similar to many M.
FT                   tuberculosis dehydrogenases e.g. P71823|Rv0768|MTCY369.13
FT                   (489 aa), FASTA score: (38.1% identity in 467 aa overlap).
FT                   Contains PS00687 Aldehyde dehydrogenases glutamic acid
FT                   active site and PS00070 Aldehyde dehydrogenases cysteine
FT                   active site. BELONGS TO THE ALDEHYDE DEHYDROGENASES
FT                   FAMILY."
FT                   /db_xref="GOA:Q7TXP5"
FT                   /db_xref="HSSP:1A4S"
FT                   /db_xref="InterPro:IPR016162"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP5"
FT                   /protein_id="CAD96570.1"
FT                   /translation="MSTTQLINPATEEVLASVDHTDANAVDDAVQRARAAQRRWARLAP
FT                   AQRAAGLRAFAAAVQAHLDELAALEVANSGHPIVSAEWEAGHVRDVLAFYAASPERLSG
FT                   RQIPVAGGVDVTFNEPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTPLTT
FT                   MRLGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMAGAAAQ
FT                   VKRVTLELGGKSANIVFHDCDLERAATTAPAGVFDNAGQDCCARSRILVQRSVYDRFME
FT                   LLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAGYVPDDAPVAFRGTAPAGRGFWFPP
FT                   TVLTPKRGDRTVTDEIFGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVA
FT                   RAVESGNLSVNSHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIAVGEEM"
FT   CDS             complement(2236..3162)
FT                   /transl_table=11
FT                   /gene="Mb2884c"
FT                   /locus_tag="Mb2884c"
FT                   /product="POSSIBLE AMIDOTRANSFERASE"
FT                   /EC_number="6.3.5.-"
FT                   /EC_number="2.-.-.-"
FT                   /note="Mb2884c, -, len: 308 aa. Equivalent to Rv2859c, len:
FT                   308 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 308 aa overlap). Possible
FT                   amidotransferase (EC 6.3.5.- or 2.-.-.-), equivalent (but
FT                   longer 58 aa) to Q9CBU9|ML1573 POSSIBLE AMIDOTRANSFERASE
FT                   from Mycobacterium leprae (249 aa), FASTA scores: opt:
FT                   1226, E(): 3e-64, (71.55% identity in 239 aa overlap). Also
FT                   similar to other amidotransferases and hypothetical
FT                   proteins, but shorter in N-terminus e.g. O88072|SCI35.37
FT                   HYPOTHETICAL 25.3 KDA PROTEIN from Streptomyces coelicolor
FT                   (242 aa), FASTA scores: opt: 683, E(): 1.2e-32, (47.65%
FT                   identity in 235 aa overlap); AAK79730|Q97I88|CAC1764
FT                   PREDICTED GLUTAMINE AMIDOTRANSFERASE from Clostridium
FT                   acetobutylicum (241 aa), FASTA scores: opt: 458, E():
FT                   1.6e-19, (32.95% identity in 246 aa overlap);
FT                   AAK75201|Q97QV9|SP1089 GLUTAMINE AMIDOTRANSFERASE CLASS I
FT                   from Streptococcus pneumoniae (229 aa), FASTA scores: opt:
FT                   431, E(): 5.6e-18, (34.75% identity in 236 aa overlap);
FT                   etc. Contains three 17 aa repeats at the N-terminus very
FT                   similar to those in other Mycobacterium tuberculosis
FT                   proteins e.g. Q10699|YY30_MYCTU|Rv2090|MT2151|MTCY49.30
FT                   PUTATIVE 5'-3' EXONUCLEASE RV2090 (EC 3.1.11.-)."
FT                   /db_xref="GOA:Q7TXP4"
FT                   /db_xref="InterPro:IPR011697"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP4"
FT                   /protein_id="CAD96571.1"
FT                   /translation="MDLSASRSDGGDPLRPASPRLRSPVSDGGDPLRPASPRLRSPVSD
FT                   GGDPLRPASPRLRSPLGASRPVVGLTAYLEQVRTGVWDIPAGYLPADYFEGITMAGGVA
FT                   VLLPPQPVDPESVGCVLDSLHALVITGGYDLDPAAYGQEPHPATDHPRPGRDAWEFALL
FT                   RGALQRGMPVLGICRGTQVLNVALGGTLHQHLPDILGHSGHRAGNGVFTRLPVHTASGT
FT                   RLAELIGESADVPCYHHQAIDQVGEGLVVSAVDVDGVIEALELPGDTFVLAVQWHPEKS
FT                   LDDLRLFKALVDAASGYAGRQSQAEPR"
FT   CDS             complement(3143..4516)
FT                   /transl_table=11
FT                   /gene="glnA4"
FT                   /locus_tag="Mb2885c"
FT                   /product="PROBABLE GLUTAMINE SYNTHETASE GLNA4 (GLUTAMINE
FT                   SYNTHASE) (GS-II)"
FT                   /EC_number="6.3.1.2"
FT                   /note="Mb2885c, glnA4, len: 457 aa. Equivalent to Rv2860c,
FT                   len: 457 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 457 aa overlap). Probable glnA4,
FT                   glutamine synthetase class II (EC 6.3.1.2), similar to many
FT                   glutamine synthases e.g. O88070|SCI35.35c from Streptomyces
FT                   coelicolor (462 aa), FASTA scores: opt: 1947, E():
FT                   8.2e-120, (64.15% identity in 452 aa overlap);
FT                   Q98H15|MLL3074 from Rhizobium loti (Mesorhizobium loti)
FT                   (465 aa), FASTA scores: opt: 1321, E(): 7.8e-79, (46.7%
FT                   identity in 452 aa overlap); Q98EM0|MLL4187 from Rhizobium
FT                   loti (Mesorhizobium loti) (456 aa), FASTA scores: opt: 698,
FT                   E(): 4.6e-38, (33.5% identity in 454 aa overlap);
FT                   Q9CDL9|GLNA from Lactococcus lactis (subsp. lactis)
FT                   (Streptococcus lactis) (446 aa), FASTA scores: opt: 633,
FT                   E(): 8.2e-34, (32.45% identity in 456 aa overlap); etc.
FT                   Also similar to three other potential glutamine synthases
FT                   in Mycobacterium tuberculosis:
FT                   Q10378|GLN2_MYCTU|GLNA2|Rv2222c|MT2280|MTCY190.33c|MTCY427.
FT                   03c PROBABLE GLUTAMINE SYNTHETASE (446 aa), FASTA score:
FT                   (31.1% identity in 453 aa overlap); Rv1878|glnA3 and
FT                   Rv2220|glnA1. BELONGS TO THE GLUTAMINE SYNTHETASE FAMILY."
FT                   /db_xref="GOA:Q7TXP3"
FT                   /db_xref="InterPro:IPR008147"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP3"
FT                   /protein_id="CAD96572.1"
FT                   /translation="MTGPGSPPLAWTELERLVAAGDVDTVIVAFTDMQGRLAGKRISGR
FT                   HFVDDIATRGVECCSYLLAVDVDLNTVPGYAMASWDTGYGDMVMTPDLSTLRLIPWLPG
FT                   TALVIADLVWADGSEVAVSPRSILRRQLDRLKARGLVADVATELEFIVFDQPYRQAWAS
FT                   GYRGLTPASDYNIDYAILASSRMEPLLRDIRLGMAGAGLRFEAVKGECNMGQQEIGFRY
FT                   DEALVTCDNHAIYKNGAKEIADQHGKSLTFMAKYDEREGNSCHIHVSLRGTDGSAVFAD
FT                   SNGPHGMSSMFRSFVAGQLATLREFTLCYAPTINSYKRFADSSFAPTALAWGLDNRTCA
FT                   LRVVGHGQNIRVECRVPGGDVNQYLAVAALIAGGLYGIERGLQLPEPCVGNAYQGADVE
FT                   RLPVTLADAAVLFEDSALVREAFGEDVVAHYLNNARVELAAFNAAVTDWERIRGFERL"
FT   CDS             complement(4676..5533)
FT                   /transl_table=11
FT                   /gene="mapB"
FT                   /locus_tag="Mb2886c"
FT                   /product="PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP)
FT                   (PEPTIDASE M)"
FT                   /EC_number="3.4.11.18"
FT                   /note="Mb2886c, mapB, len: 285 aa. Equivalent to Rv2861c,
FT                   len: 285 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 285 aa overlap). Probable mapB
FT                   (alternate gene name: map), methionine aminopeptidase (EC
FT                   3.4.11.18), equivalent to Q9CBU7|MAPB|ML1576 METHIONINE
FT                   AMINOPEPTIDASE from Mycobacterium leprae (285 aa), FASTA
FT                   scores: opt: 1729, E(): 1e-99, (89.75% identity in 283 aa
FT                   overlap). Also highly similar to many e.g. Q9RKR2|MAP3 from
FT                   Streptomyces coelicolor (285 aa), FASTA scores: opt: 1385,
FT                   E(): 2e-78, (70.65% identity in 283 aa overlap);
FT                   Q9SW64|C7A10.320|AT4G37040 from Arabidopsis thaliana
FT                   (Mouse-ear cress) (305 aa), FASTA scores: opt: 914, E():
FT                   3e-49, (50.35% identity in 286 aa overlap);
FT                   P07906|AMPM_ECOLI|MAP|B0168|Z0178|ECS0170 from Escherichia
FT                   coli strains K12 and O157:H7 (264 aa), FASTA scores: opt:
FT                   793, E(): 8.5e-42, (51.0% identity in 245 aa overlap); etc.
FT                   BELONGS TO PEPTIDASE FAMILY M24A; ALSO KNOWN AS THE MAP
FT                   FAMILY 1. COFACTOR: COBALT; BINDS 2 IONS PER SUBUNIT. Note
FT                   that this gene has an N-terminal extension present in the
FT                   human map, but not in the prokaryotic map's. An alternative
FT                   start, with RBS, will give a protein equivalent to the
FT                   shorter prokaryotic map's."
FT                   /db_xref="GOA:P0A5J3"
FT                   /db_xref="HSSP:1C24"
FT                   /db_xref="InterPro:IPR002467"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5J3"
FT                   /protein_id="CAD96573.1"
FT                   /translation="MPSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPE
FT                   VIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSC
FT                   CTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRT
FT                   REATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQ
FT                   PAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEI
FT                   LTCL"
FT   CDS             complement(5575..6159)
FT                   /transl_table=11
FT                   /gene="Mb2887c"
FT                   /locus_tag="Mb2887c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2887c, -, len: 194 aa. Equivalent to Rv2862c, len:
FT                   194 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.0% identity in 194 aa overlap). Conserved hypothetical
FT                   protein, showing some similarity with others e.g.
FT                   Q9X8X5|SCH35.31c HYPOTHETICAL 19.6 KDA PROTEIN from
FT                   Streptomyces coelicolor (180 aa), FASTA scores: opt: 266,
FT                   E(): 2.2e-11, (34.65% identity in 179 aa overlap);
FT                   Q9Z5H1|ML0169|MLCB373.19 HYPOTHETICAL 22.1 KDA PROTEIN from
FT                   Mycobacterium leprae (200 aa), FASTA scores: opt: 195, E():
FT                   2.3e-06, (30.15% identity in 189 aa overlap); etc. Also
FT                   some similarity to
FT                   P71544|Y966_MYCTU|Rv0966c|MT0994|MTCY10D7.08 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (230
FT                   aa), FASTA scores: opt: 209, E(): 2.6e-07, (31.5% identity
FT                   in 184 aa overlap)."
FT                   /db_xref="InterPro:IPR012551"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP2"
FT                   /protein_id="CAD96574.1"
FT                   /translation="MTETGGDMVALRVSDADPNGTMRRLHNAVALGLINIDEFEQRSSR
FT                   VSFARTRSELDGLVGDLPRPGAIVTSAADRVELRGWAGSLKRHGEWIVPTRLALVRRLG
FT                   SIELDLVKARFAGPVVVIELDMMFGSLEVRLPNGASASIDDVEVYVGSASDRRKDAPAE
FT                   GTPHVVLTGRMVCGSVVIKGPRRALLRRHRG"
FT   CDS             6508..6888
FT                   /transl_table=11
FT                   /gene="Mb2888"
FT                   /locus_tag="Mb2888"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2888, -, len: 126 aa. Equivalent to Rv2863, len:
FT                   126 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 126 aa overlap). Conserved hypothetical
FT                   protein, similar to hypothetical proteins from
FT                   Mycobacterium tuberculosis e.g.
FT                   Q50595|YI38_MYCTU|Rv1838c|MT1886|MTCY1A11.05|MTCY359.35
FT                   CONSERVED HYPOTHETICAL PROTEIN (131 aa), FASTA scores: opt:
FT                   299, E(): 6.5e-15, (39.0% identity in 123 aa overlap)."
FT                   /db_xref="InterPro:IPR002716"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP1"
FT                   /protein_id="CAD96575.1"
FT                   /translation="MIFVDTNVFMYAVGRDHPLRMPAREFLEHSLEHQDRLVTSAEAMQ
FT                   ELLNAYVPVGRNSTLDSALTLVRALTEIWPVEAADVAHARTLHHRHPGLGARDLLHLAC
FT                   CQRRGVTRIKTFDHTLASAFRS"
FT   CDS             complement(6970..8781)
FT                   /transl_table=11
FT                   /gene="Mb2889c"
FT                   /locus_tag="Mb2889c"
FT                   /product="POSSIBLE PENICILLIN-BINDING LIPOPROTEIN"
FT                   /note="Mb2889c, -, len: 603 aa. Equivalent to Rv2864c, len:
FT                   603 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 603 aa overlap). Possible
FT                   penicillin-binding lipoprotein, probably located in
FT                   periplasm, equivalent to Q9CBU6|ML1577 PROBABLE PENICILLIN
FT                   BINDING PROTEIN from Mycobacterium leprae (608 aa), FASTA
FT                   scores: opt: 3352, E(): 2.1e-193, (81.5% identity in 606 aa
FT                   overlap). Also shows some similarity to others e.g.
FT                   P72405|PCBR from Streptomyces clavuligerus (551 aa), FASTA
FT                   scores: opt: 543, E(): 6.1e-25, (28.4% identity in 567 aa
FT                   overlap); Q9F2L0|SCH63.18c from Streptomyces coelicolor
FT                   (546 aa), FASTA scores: opt: 519, E(): 1.7e-23, (29.3%
FT                   identity in 577 aa overlap); Q9RKD1|SCE87.07 from
FT                   Streptomyces coelicolor (541 aa), FASTA scores: opt: 472,
FT                   E(): 1.1e-20, (34.3% identity in 318 aa overlap); etc.
FT                   Equivalent to AAK47258 from Mycobacterium tuberculosis
FT                   strain CDC1551 (618 aa) but shorter 15 aa. Contains signal
FT                   sequence and appropriately positioned PS00013 Prokaryotic
FT                   membrane lipoprotein lipid attachment site, and PS00017
FT                   ATP/GTP-binding site motif A (P-loop)."
FT                   /db_xref="GOA:Q7TXP0"
FT                   /db_xref="InterPro:IPR001460"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXP0"
FT                   /protein_id="CAD96576.1"
FT                   /translation="MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAI
FT                   GDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQVLSAKYAEDTGTVAYRFSWHLPKD
FT                   RIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTDVLV
FT                   PGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLH
FT                   ADDSNRVAAAIGQLPGVVITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSV
FT                   NQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNTRGGKAMIVVIKPSTGEILAI
FT                   AQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPN
FT                   YGGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGS
FT                   VPPTVDLAERTEDGFGQGKVLASPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPI
FT                   SQKMIDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGSHSWFAGYRGDLAFASL
FT                   IVGGGSSEYAVRMTKVMFESLPPGYLA"
FT   CDS             9053..9334
FT                   /transl_table=11
FT                   /gene="Mb2890"
FT                   /locus_tag="Mb2890"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2890, -, len: 93 aa. Equivalent to Rv2865, len: 93
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 93 aa overlap). Conserved hypothetical protein,
FT                   showing weak similarity with P58235|YR54_SYNY3|SSR2754
FT                   HYPOTHETICAL 9.7 KDA PROTEIN from Synechocystis sp. strain
FT                   PCC 6803 (87 aa), FASTA scores: opt: 134, E(): 0.007,
FT                   (30.65% identity in 75 aa overlap); BAB58570|SAV2408
FT                   CONSERVED HYPOTHETICAL PROTEIN from Staphylococcus aureus
FT                   subsp. aureus Mu50 (83 aa), FASTA scores: opt: 124, E():
FT                   0.037, (27.5% identity in 80 aa overlap). Also similar to
FT                   Rv1247|MTV006.19c HYPOTHETICAL 9.8 KDA PROTEIN from
FT                   Mycobacterium tuberculosis (89 aa), FASTA scores: opt: 249,
FT                   E(): 2.6e-11, (44.2% identity in 86 aa overlap)."
FT                   /db_xref="InterPro:IPR006442"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN9"
FT                   /protein_id="CAD96577.1"
FT                   /translation="MRILPISTIKGKLNEFVDAVSSTQDQITITKNGAPAAVLVGADEW
FT                   ESLQETLYWLAQPGIRESIAEADADIASGRTYGEDEIRAEFGVPRRPH"
FT   CDS             9338..9601
FT                   /transl_table=11
FT                   /gene="Mb2891"
FT                   /locus_tag="Mb2891"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2891, -, len: 87 aa. Equivalent to Rv2866, len: 87
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 87 aa overlap). Conserved hypothetical protein,
FT                   similar to O50461|Rv1246c|MTV006.18c CONSERVED HYPOTHETICAL
FT                   PROTEIN from Mycobacterium tuberculosis (97 aa), FASTA
FT                   scores: opt: 290, E(): 3.6e-16, (54.1% identity in 85 aa
FT                   overlap)."
FT                   /db_xref="InterPro:IPR007712"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN8"
FT                   /protein_id="CAD96578.1"
FT                   /translation="MPYTVRFTTTARRDLHKLPPRILAAVVEFAFGDLSREPLRVGKPL
FT                   RRELAGTFSARRGTYRLLYRIDDEHTTVVILRVDHRADIYRR"
FT   CDS             complement(9974..10828)
FT                   /transl_table=11
FT                   /gene="Mb2892c"
FT                   /locus_tag="Mb2892c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2892c, -, len: 284 aa. Equivalent to Rv2867c, len:
FT                   284 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 284 aa overlap). Conserved hypothetical
FT                   protein, similar to Q9KYR8|SC5H4.21 HYPOTHETICAL 31.3 KDA
FT                   PROTEIN from Streptomyces coelicolor (287 aa), FASTA
FT                   scores: opt: 798, E(): 2.4e-45, (47.95% identity in 269 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7TXN7"
FT                   /db_xref="InterPro:IPR016794"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96579.1"
FT                   /translation="MSAPPISRLVGERQVSVVRDAAAVWRVLDDDPIESCMVAARVADH
FT                   GIDPNAIGGELWTRRGAHESLCFAGANLIPLRGGPIDLNAFADVAMSTPRRCSSLVGRA
FT                   DLVLPMWQRLEPVWGPARDVRDNQPLMALATHPSCAIDTGVRQVRPEELDSYLVAAVDM
FT                   FIGEVGVDPRLGDGGRGYRRRVAGLIAAGRAWARFEHGQVIFKAEVGSQSPAVGQIQGV
FT                   WVHPEWRGIGLGTAGTATLAAVIVGSGRIASLYVNSFNTVARAAYARVGFKEIGTFATV
FT                   LLD"
FT   CDS             complement(10884..12047)
FT                   /transl_table=11
FT                   /gene="gcpE"
FT                   /locus_tag="Mb2893c"
FT                   /product="PROBABLE GCPE PROTEIN"
FT                   /note="Mb2893c, gcpE, len: 387 aa. Equivalent to Rv2868c,
FT                   len: 387 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 387 aa overlap). Probable gcpE protein
FT                   (protein e), equivalent to Q9CBU5|GCPE|ML1581 HYPOTHETICAL
FT                   PROTEIN GCPE from Mycobacterium leprae (392 aa), FASTA
FT                   scores: opt: 2247, E(): 6.8e-134, (87.65% identity in 388
FT                   aa overlap). Highly similar to essential gene of unknown
FT                   function from Escherichia coli and other prokaryotes e.g.
FT                   Q9X7W2|GCPE_STRCO|SC6A5.16 GCPE PROTEIN HOMOLOG from
FT                   Streptomyces coelicolor (384 aa), FASTA scores: opt: 1965,
FT                   E(): 3.8e-116, (78.2% identity in 385 aa overlap);
FT                   P54482|GCPE_BACSU GCPE PROTEIN HOMOLOG from Bacillus
FT                   subtilis (377 aa), FASTA scores: opt: 1157, E(): 2.6e-65,
FT                   (49.55% identity in 351 aa overlap);
FT                   P27433|GCPE_ECOLI|B2515|Z3778|ECS3377 GCPE PROTEIN (PROTEIN
FT                   E) from Escherichia coli strains K12 and O157:H7 (372 aa),
FT                   FASTA scores: opt: 984, E(): 2e-54, (44.15% identity in 360
FT                   aa overlap); etc. BELONGS TO THE GCPE FAMILY."
FT                   /db_xref="GOA:Q7TXN6"
FT                   /db_xref="InterPro:IPR004588"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXN6"
FT                   /protein_id="CAD96580.1"
FT                   /translation="MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTT
FT                   KTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIF
FT                   AAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKAT
FT                   PEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGP
FT                   AFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCP
FT                   SCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIF
FT                   VRGEVIKTVPEAQIVETLIEEAMRLAAEMGEQAPGATPSGSPIVTVS"
FT   CDS             complement(12064..13278)
FT                   /transl_table=11
FT                   /gene="Mb2894c"
FT                   /locus_tag="Mb2894c"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2894c, -, len: 404 aa. Equivalent to Rv2869c, len:
FT                   404 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 404 aa overlap). Probable conserved
FT                   transmembrane protein, equivalent to Q9CBU4|ML1582 PROBABLE
FT                   INTEGRAL MEMBRANE PROTEIN from Mycobacterium leprae (404
FT                   aa), FASTA scores: opt: 2250, E(): 1.1e-128, (82.2%
FT                   identity in 404 aa overlap). Also weakly similar to other
FT                   membrane proteins or hypothetical proteins e.g.
FT                   Q9A710|CC1916 PUTATIVE MEMBRANE-ASSOCIATED ZINC
FT                   METALLOPROTEASE from Caulobacter crescentus (398 aa), FASTA
FT                   scores: opt: 368, E(): 7.8e-15, (28.1% identity in 427 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7TXN5"
FT                   /db_xref="InterPro:IPR008915"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN5"
FT                   /protein_id="CAD96581.1"
FT                   /translation="MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGP
FT                   TLWSTRRGETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGP
FT                   GMNLAICLVLIYAIALVWGLPNLHPPTRAVIGETGCVAQEVSQGKLEQCTGPGPAALAG
FT                   IRSGDVVVKVGDTPVSSFDEMAAAVRKSHGSVPIVVERDGTAIVTYVDIESTQRWIPNG
FT                   QGGELQPATVGAIGVGAARVGPVRYGVFSAMPATFAFTGDLTVEVGKALAALPTKVGAL
FT                   VRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLILAAINLLPLLPFD
FT                   GGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATYVVLVLVVGYMLLTVTADLVNP
FT                   IRLFQ"
FT   CDS             complement(13286..14527)
FT                   /transl_table=11
FT                   /gene="dxr"
FT                   /locus_tag="Mb2895c"
FT                   /product="PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE
FT                   REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE)
FT                   (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERASE)"
FT                   /EC_number="1.1.1.-"
FT                   /note="Mb2895c, dxr, len: 413 aa. Equivalent to Rv2870c,
FT                   len: 413 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 413 aa overlap). Probable dxr,
FT                   1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC
FT                   1.1.1.-), equivalent to Q9CBU3|DXR|ML1583
FT                   1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE from
FT                   Mycobacterium leprae (406 aa), FASTA scores: opt: 2145,
FT                   E(): 1e-124, (84.05% identity in 395 aa overlap). Also
FT                   highly similar to others e.g. Q9AJD7|DXR from Kitasatospora
FT                   griseola (Streptomyces griseolosporeus) (386 aa), FASTA
FT                   scores: opt: 1176, E(): 5.2e-65, (56.45% identity in 388 aa
FT                   overlap); Q9KYS1|DXR_STRCO|SC5H4.18 from Streptomyces
FT                   coelicolor (401 aa), FASTA scores: opt: 1079, E(): 5.1e-59,
FT                   (52.25% identity in 396 aa overlap); P45568|DXR|B0173 from
FT                   Escherichia coli strain K12 (398 aa), FASTA scores: opt:
FT                   120, E(): 0.032, (52.9% identity in 34 aa overlap); etc.
FT                   Contains PS00133 Zinc carboxypeptidases, zinc-binding
FT                   region 2 signature. BELONGS TO THE DXR FAMILY. N-terminus
FT                   shortened since first submission."
FT                   /db_xref="GOA:P64013"
FT                   /db_xref="HSSP:1JVS"
FT                   /db_xref="InterPro:IPR013512"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64013"
FT                   /protein_id="CAD96582.1"
FT                   /translation="MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLA
FT                   AGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNAL
FT                   VGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRG
FT                   GTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLE
FT                   VIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRV
FT                   SGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAG
FT                   RIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAK
FT                   PGAAGRHASTLERS"
FT   CDS             14654..14911
FT                   /transl_table=11
FT                   /gene="Mb2896"
FT                   /locus_tag="Mb2896"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2896, -, len: 85 aa. Equivalent to Rv2871, len: 85
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 85 aa overlap). Conserved hypothetical protein
FT                   (see citation below), similar to other CONSERVED
FT                   HYPOTHETICAL PROTEINS from Mycobacterium tuberculosis
FT                   strains H37Rv and CDC1551 e.g. O50456|Rv1241|MTV006.13 (86
FT                   aa), FASTA scores: opt: 172, E(): 2.9e-05, (37.2% identity
FT                   in 86 aa overlap); O53811|Rv0748|MTV041.22 (85 aa), FASTA
FT                   scores: opt: 170, E(): 4e-05, (35.3% identity in 85 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:P0A5H0"
FT                   /db_xref="InterPro:IPR002145"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5H0"
FT                   /protein_id="CAD96583.1"
FT                   /translation="MRTTIRIDDELYREVKAKAARSGRTVAAVLEDAVRRGLNPPKPQA
FT                   AGRYRVQPSGKGGLRPGVDLSSNAALAEAMNDGVSVDAVR"
FT   CDS             14898..15341
FT                   /transl_table=11
FT                   /gene="Mb2897"
FT                   /locus_tag="Mb2897"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2897, -, len: 147 aa. Equivalent to Rv2872, len:
FT                   147 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 147 aa overlap). Conserved hypothetical
FT                   protein (see citation below), similar to other CONSERVED
FT                   HYPOTHETICAL PROTEINS from Mycobacterium tuberculosis
FT                   strains H37Rv and CDC1551 e.g. O53683|Rv0277c|MTV035.05c
FT                   (142 aa), FASTA scores: opt: 357, E(): 1.4e-17, (41.45%
FT                   identity in 140 aa overlap); O53812|Rv0749|MTV041.23 (142
FT                   aa), FASTA scores: opt: 350, E(): 4.3e-17, (41.55% identity
FT                   in 142 aa overlap); etc."
FT                   /db_xref="InterPro:IPR006226"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65044"
FT                   /protein_id="CAD96584.1"
FT                   /translation="MLCVDVNVLVYAHRADLREHADYRGLLERLANDDEPLGLPDSVLA
FT                   GFIRVVTNRRVFTEPTSPQDAWQAVDALLAAPAAMRLRPGERHWMAFRQLASDVDANGN
FT                   DIADAHLAAYALENNATWLSADRGFARFRRLRWRHPLDGQTHL"
FT   CDS             15421..16083
FT                   /transl_table=11
FT                   /gene="mpb83"
FT                   /locus_tag="Mb2898"
FT                   /standard_name="mpt83"
FT                   /product="CELL SURFACE LIPOPROTEIN MPB83 (LIPOPROTEIN P23)"
FT                   /note="Mb2898, mpb83, len: 220 aa. Equivalent to Rv2873,
FT                   len: 220 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 220 aa overlap). mpt83 (alternate gene
FT                   name: mpb83), cell surface lipoprotein (see citations
FT                   below). Also similar to upstream ORF
FT                   Q50769|MP70_MYCTU|MPT70|MPB70|Rv2875|MT2943|MTCY274.06
FT                   which is also known as MAJOR SECRETED IMMUNOGENIC PROTEIN
FT                   MPT70 PRECURSOR from Mycobacterium tuberculosis (193 aa),
FT                   FASTA scores: opt: 806, E(): 2.7e-38, (70.25% identity in
FT                   185 aa overlap). BELONGS TO THE MPT70 / MPT83 FAMILY.
FT                   ATTACHED TO THE MEMBRANE BY A LIPID ANCHOR."
FT                   /db_xref="GOA:P0A671"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0CAX7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96585.1"
FT                   /translation="MINVQAKPAAAASLAAIAIAFLAGCSSTKPVSQDTSPKPATSPAA
FT                   PVTTAAMADPAADLIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNPMLSTLTSALS
FT                   GKLNPDVNLVDTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQA
FT                   SPSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ"
FT   CDS             16363..18450
FT                   /transl_table=11
FT                   /gene="dipZ"
FT                   /locus_tag="Mb2899"
FT                   /product="POSSIBLE INTEGRAL MEMBRANE C-TYPE CYTOCHROME
FT                   BIOGENESIS PROTEIN DIPZ"
FT                   /note="Mb2899, dipZ, len: 695 aa. Equivalent to Rv2874,
FT                   len: 695 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 695 aa overlap). Possible dipZ,
FT                   cytochrome c-type biogenesis protein (see citation below),
FT                   probable integral membrane protein, similar in part to
FT                   others or hypothetical proteins e.g. CAC48606|SMB20213
FT                   CONSERVED HYPOTHETICAL PROTEIN from Rhizobium meliloti
FT                   (Sinorhizobium meliloti) (627 aa), FASTA scores: opt: 844,
FT                   E(): 7.3e-43, (32.65% identity in 643 aa overlap);
FT                   Q9ZMH0|CCDA OR JHP0250 PUTATIVE CYTOCHROME C-TYPE
FT                   BIOGENESIS PROTEIN from Helicobacter pylori J99
FT                   (Campylobacter pylori J99) (239 aa), FASTA scores: opt:
FT                   250, E(): 1.4e-07, (27.3% identity in 227 aa overlap);
FT                   Q9LA04|CCDA C-TYPE CYTOCHROME BIOGENESIS PROTEIN from
FT                   Rhodobacter capsulatus (Rhodopseudomonas capsulata) (252
FT                   aa), FASTA scores: opt: 245, E(): 2.9e-07, (27.85% identity
FT                   in 244 aa overlap); etc. Also similar to
FT                   O06393|CCSA|Rv0527|MTCY25D10.06 CYTOCHROME C-TYPE
FT                   BIOGENESIS PROTEIN from Mycobacterium tuberculosis (259
FT                   aa), FASTA scores: opt: 280, E(): 2.4e-09, (29.3% identity
FT                   in 239 aa overlap)."
FT                   /db_xref="GOA:P59960"
FT                   /db_xref="InterPro:IPR003834"
FT                   /db_xref="UniProtKB/Swiss-Prot:P59960"
FT                   /protein_id="CAD96586.1"
FT                   /translation="MVESRRAAAAASAYASRCGIAPATSQRSLATPPTISVPSGEGRCR
FT                   CHVARGAGRDPRRRLRRRRWCGRCGYHSHLTGGEFDVNRLCQQRSRERSCQLVAVPADP
FT                   RPKRQRITDVLTLALVGFLGGLITGISPCILPVLPVIFFSGAQSVDAAQVAKPEGAVAV
FT                   RRKRALSATLRPYRVIGGLVLSFGMVTLLGSALLSVLHLPQDAIRWAALVALVAIGAGL
FT                   IFPRFEQLLEKPFSRIPQKQIVTRSNGFGLGLALGVLYVPCAGPILAAIVVAGATATIG
FT                   LGTVVLTATFALGAALPLLFFALAGQRIAERVGAFRRRQREIRIATGSVTILLAVALVF
FT                   DLPAALQRAIPDYTASLQQQISTGTEIREQLNLGGIVNAQNAQLSNCSDGAAQLESCGT
FT                   APDLKGITGWLNTPGNKPIDLKSLRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSG
FT                   LAVIGVHTPEYAFEKVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDAT
FT                   GTVRHIKFGEGDYNVTETLVRQLLNDAKPGVKLPQPSSTTTPDLTPRAALTPETYFGVG
FT                   KVVNYGGGGAYDEGSAVFDYPPSLAANSFALRGRWALDYQGATSDGNDAAIKLNYHAKD
FT                   VYIVVGGTGTLTVVRDGKPATLPISGPPTTHQVVAGDRLASETLEVRPSKGLQVFSFTY
FT                   G"
FT   CDS             18546..19127
FT                   /transl_table=11
FT                   /gene="mpb70"
FT                   /locus_tag="Mb2900"
FT                   /standard_name="mpt70"
FT                   /product="MAJOR SECRETED IMMUNOGENIC PROTEIN MPB70
FT                   PRECURSOR"
FT                   /note="Mb2900, mpb70, len: 193 aa. Equivalent to Rv2875,
FT                   len: 193 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 193 aa overlap). mpt70 (alternate gene
FT                   name: mpb70), major secreted immunogenic protein MPT70
FT                   precursor (see citations below). Also similar to downstream
FT                   ORF Q10790|MP83_MYCTU|MPT83|MPB83|Rv2873|MT2940|MTCY274.04
FT                   CELL SURFACE LIPOPROTEIN MPT83 PRECURSOR (LIPOPROTEIN P23)
FT                   (220 aa), FASTA scores: opt: 806, E(): 1.2e-40, (70.25%
FT                   identity in 185 aa overlap). BELONGS TO THE MPT70 / MPT83
FT                   FAMILY. GENERALLY FOUND AS A MONOMER; HOMODIMER IN CULTURE
FT                   FLUIDS."
FT                   /db_xref="GOA:P0A669"
FT                   /db_xref="InterPro:IPR000782"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A669"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96587.1"
FT                   /translation="MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAAN
FT                   PTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNA
FT                   AFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSL
FT                   KVGNADVVCGGVSTANATVYMIDSVLMPPA"
FT   CDS             19179..19493
FT                   /transl_table=11
FT                   /gene="Mb2901"
FT                   /locus_tag="Mb2901"
FT                   /product="POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2901, -, len: 104 aa. Equivalent to Rv2876, len:
FT                   104 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.0% identity in 104 aa overlap). Possible conserved
FT                   transmembrane protein, equivalent (but longer 16 aa) to
FT                   Q9CBU2|ML1584 POSSIBLE CONSERVED MEMBRANE PROTEIN from
FT                   Mycobacterium leprae (84 aa), FASTA scores: opt: 444, E():
FT                   8.3e-26, (73.85% identity in 88 aa overlap)."
FT                   /db_xref="GOA:Q7TXN4"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN4"
FT                   /protein_id="CAD96588.1"
FT                   /translation="MFGQWEFDVSPTGGIAVASTEVEHFAGSQHEVDTAEVPSAAWGRS
FT                   RIDHRTWHIVGLCIFGFLLAMLRGNHVGHVEDWFLITFAAVVLFVLARDLWGRRRGWIR
FT                   "
FT   CDS             complement(19524..20387)
FT                   /transl_table=11
FT                   /gene="Mb2902c"
FT                   /locus_tag="Mb2902c"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN"
FT                   /note="Mb2902c, -, len: 287 aa. Equivalent to Rv2877c, len:
FT                   287 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 287 aa overlap). Probable conserved
FT                   integral membrane protein, Mer family possibly involved in
FT                   transport of mercury, similar to others, and to the fourth
FT                   protein of the mercury resistance operon of Streptomyces sp
FT                   (or other organisms), and to putative cytochrome-c
FT                   biogenesis proteins e.g. Q9XBD1|CZA382.20C PUTATIVE
FT                   INTEGRAL MEMBRANE TRANSPORTER from Amycolatopsis orientalis
FT                   (298 aa), FASTA scores: opt: 913, E(): 7.6e-46, (51.55%
FT                   identity in 293 aa overlap); P30344|MER4_STRLI MERCURY
FT                   RESISTANCE PROBABLE HG TRANSPORT PROTEIN from Streptomyces
FT                   lividans (319 aa), FASTA scores: opt: 427, E(): 1.2e-17,
FT                   (32.85% identity in 289 aa overlap); Q9M5P3 PUTATIVE
FT                   CYTOCHROME C BIOGENESIS PROTEIN PRECURSOR from Arabidopsis
FT                   thaliana (Mouse-ear cress) (354 aa), FASTA scores: opt:
FT                   229, E(): 4e-06, (29.85% identity in 221 aa overlap); etc.
FT                   Contains PS00044 Bacterial regulatory proteins, lysR family
FT                   signature. Note that previously known as merT."
FT                   /db_xref="GOA:Q7TXN3"
FT                   /db_xref="InterPro:IPR003834"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN3"
FT                   /protein_id="CAD96589.1"
FT                   /translation="MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVHGQDSAGRTGP
FT                   LSAVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLPYATVLIGLALIALGGWLL
FT                   LGRGLTALTPRSLGVRWAPTVRLGSMYGYGISYAVASLSCTIGPFLAVTGAGLRGGSVV
FT                   GSVAIYLAYVAGLTLVVGVLAVAAATASSALADRLRRILPFVNRISGALLVVVGLYVGY
FT                   YGLYELRLIAGVGANPQDAVIAAAGRLQGALAGWVNQHGAWPWAVLLVVLVVGAFAGTW
FT                   FRRVRR"
FT   CDS             complement(20392..20913)
FT                   /transl_table=11
FT                   /gene="mpb53"
FT                   /locus_tag="Mb2903c"
FT                   /standard_name="mpt53"
FT                   /product="SOLUBLE SECRETED ANTIGEN MPB53"
FT                   /note="Mb2903c, mpb53, len: 173 aa. Equivalent to Rv2878c,
FT                   len: 173 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 173 aa overlap). mpt53, secreted
FT                   protein (contains N-terminal signal sequence) (see
FT                   citations below). Shows some similarity with several
FT                   disulfide bond interchange proteins e.g. P43787|THIX_HAEIN
FT                   THIOREDOXIN-LIKE PROTEIN HI1115 from Haemophilus influenzae
FT                   (167 aa), FASTA scores: opt: 200, E(): 1.4e-06, (28.9%
FT                   identity in 135 aa overlap); P52237|TIPB_PSEFL
FT                   THIOL:DISULFIDE INTERCHANGE PROTEIN TIPB PRECURSOR
FT                   (CYTOCHROME C BIOGENESIS PROTEIN TIPB) (178 aa), FASTA
FT                   scores: opt: 184, E(): 1.8e-05, (26.3% identity in 171 aa
FT                   overlap); etc. Also highly similar to
FT                   O53924|DSBF|Rv1677|MTV047.12 PUTATIVE LIPOPROTEIN from
FT                   Mycobacterium tuberculosis (182 aa), FASTA scores: opt:
FT                   482, E(): 5.7e-26, (52.8% identity in 142 aa overlap).
FT                   COULD BE BELONG TO THE THIOREDOXIN FAMILY. Note that also
FT                   previously known as dsbE."
FT                   /db_xref="GOA:P0A619"
FT                   /db_xref="InterPro:IPR000866"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A619"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96590.1"
FT                   /translation="MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFT
FT                   ATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADV
FT                   GAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDE
FT                   LSGRVAALTS"
FT   CDS             complement(21099..22193)
FT                   /transl_table=11
FT                   /gene="Mb2904c"
FT                   /locus_tag="Mb2904c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2904c, -, len: 364 aa. Equivalent to 5' end of
FT                   Rv2880c and 3' end of Rv2879c, len: 275 aa and 189 aa, from
FT                   Mycobacterium tuberculosis strain H37Rv, (100.0% identity
FT                   in 177 aa overlap and 100.0% identity in 188 aa overlap).
FT                   Rv2880c: Conserved hypothetical protein, highly similar in
FT                   N-terminus to others e.g. O86754|SC6A9.22c HYPOTHETICAL
FT                   40.4 KDA PROTEIN from Streptomyces coelicolor (368 aa),
FT                   FASTA scores: opt: 663, E(): 2.6e-33, (52.6% identity in
FT                   213 aa overlap); Q55880|Y098_SYNY3|SLL0098 HYPOTHETICAL
FT                   38.9 KDA PROTEIN from Synechocystis sp. strain PCC 6803
FT                   (350 aa), FASTA scores: opt: 362, E(): 7.3e-15, (38.9%
FT                   identity in 162 aa overlap); O66732|AQ_416 HYPOTHETICAL
FT                   40.2 KDA PROTEIN from Aquifex aeolicus (348 aa), FASTA
FT                   scores: opt: 321, E(): 2.4e-12, (39.75% identity in 146 aa
FT                   overlap); etc. Appears to be a frame shift with respect to
FT                   preceding ORF but we can detect no error in the cosmid
FT                   sequence to account for this. Rv2879c: Conserved
FT                   hypothetical protein, similar to others e.g. C-terminus of
FT                   Q9RVT6|DR0936 CONSERVED HYPOTHETICAL PROTEIN from
FT                   Deinococcus radiodurans (346 aa), FASTA scores: opt: 505,
FT                   E(): 1e-26, (46.5% identity in 185 aa overlap);
FT                   O34617|YLON_BACSU HYPOTHETICAL 41.6 KDA PROTEIN from
FT                   Bacillus subtilis (363 aa), FASTA scores: opt: 459, E():
FT                   1.2e-24, (40.5% identity in 185 aa overlap);
FT                   YFGB_ECOLI|P36979 hypothetical 43.1 kd protein from
FT                   Escherichia coli (384 aa), FASTA scores, opt: 410, E():
FT                   2.8e-21, (41.7% identity in 187 aa overlap); etc. Appears
FT                   to be a frame shift with respect to following ORF but we
FT                   can detect no error in the cosmid sequence to account for
FT                   this. REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2880c and Rv2879c exist as 2
FT                   genes. In Mycobacterium bovis, a single base deletion (g-*)
FT                   leads to a single product."
FT                   /db_xref="GOA:P0A645"
FT                   /db_xref="InterPro:IPR007197"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A645"
FT                   /protein_id="CAD96591.1"
FT                   /translation="MVPELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLA
FT                   HQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKTLWRAVDGTM
FT                   FESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAGAAALRDD
FT                   FGDRLSNVVFMGMGEPLANYARVLAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNL
FT                   ADARLGVTLALSLHAPDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIR
FT                   DVNDQPWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAKGV
FT                   SCTVRDTRGREISAACGQLAAVGG"
FT   CDS             complement(22216..23136)
FT                   /transl_table=11
FT                   /gene="cdsA"
FT                   /locus_tag="Mb2905c"
FT                   /product="PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE
FT                   CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE)
FT                   (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL
FT                   SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE)
FT                   (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE)"
FT                   /EC_number="2.7.7.41"
FT                   /note="Mb2905c, cdsA, len: 306 aa. Equivalent to Rv2881c,
FT                   len: 306 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 306 aa overlap). Probable cdsA,
FT                   phosphatidate cytidylyltransferase (EC 2.7.7.41), integral
FT                   membrane protein, equivalent to Q9CBU1|CDSA_MYCLE|ML1589
FT                   PHOSPHATIDATE CYTIDYLYLTRANSFERASE from Mycobacterium
FT                   leprae (312 aa), FASTA scores: opt: 1470, E(): 1.1e-84,
FT                   (70.3% identity in 313 aa overlap). Also similar to others
FT                   e.g. Q9KPV7|VC2255 from Vibrio cholerae (280 aa), FASTA
FT                   scores: opt: 383, E(): 1.1e-16, (29.3% identity in 280 aa
FT                   overlap); Q9CDT2|CDSA from Lactococcus lactis (subsp.
FT                   lactis) (Streptococcus lactis) (267 aa), FASTA scores: opt:
FT                   361, E(): 2.6e-15, (29.05% identity in 265 aa overlap);
FT                   P06466|CDSA_ECOLI|CDS|B0175|Z0186|ECS0177 from Escherichia
FT                   coli strains K12 and O157:H7 (249 aa), FASTA scores: opt:
FT                   352, E(): 9.2e-15, (40.4% identity in 156 aa overlap); etc.
FT                   Contains PS00017 ATP/GTP-binding site motif A (P-loop).
FT                   BELONGS TO THE CDS FAMILY."
FT                   /db_xref="GOA:P63759"
FT                   /db_xref="InterPro:IPR000374"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63759"
FT                   /protein_id="CAD96592.1"
FT                   /translation="MTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIG
FT                   LVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQAAVWLTWPF
FT                   GAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVPLFC
FT                   SFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSL
FT                   VCGITATIITATFLVGKTPWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGH
FT                   GGLMDRLDGILPSAVAAWIVLTLLP"
FT   CDS             complement(23159..23716)
FT                   /transl_table=11
FT                   /gene="frr"
FT                   /locus_tag="Mb2906c"
FT                   /product="RIBOSOME RECYCLING FACTOR FRR (RIBOSOME RELEASING
FT                   FACTOR) (RRF)"
FT                   /note="Mb2906c, frr, len: 185 aa. Equivalent to Rv2882c,
FT                   len: 185 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 185 aa overlap). Probable frr, ribosome
FT                   recycling factor, equivalent to
FT                   O33046|RRF_MYCLE|FRR|ML1590|MLCB250.76 RIBOSOME RECYCLING
FT                   FACTOR from Mycobacterium leprae (185 aa), FASTA scores:
FT                   opt: 1063, E(): 2.6e-60, (90.8% identity in 185 aa
FT                   overlap). Also highly similar to others e.g.
FT                   O86770|RRF_STRCO|FRR|SC6A9.40c from Streptomyces coelicolor
FT                   (185 aa), FASTA scores: opt: 783, E(): 1.5e-42, (63.25%
FT                   identity in 185 aa overlap); P81101|RRF_BACSU|FRR from
FT                   Bacillus subtilis (184 aa), FASTA scores: opt: 640, E():
FT                   1.7e-33, (51.65% identity in 182 aa overlap);
FT                   P16174|RRF_ECOLI|FRR|B0172|Z0183|ECS0174 from Escherichia
FT                   coli strains K12 and O157:H7 (185 aa), FASTA scores: opt:
FT                   473, E(): 1.4e-23, (40.2% identity in 184 aa overlap); etc.
FT                   BELONGS TO THE RRF FAMILY."
FT                   /db_xref="GOA:P66735"
FT                   /db_xref="HSSP:1GE9"
FT                   /db_xref="InterPro:IPR015998"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66735"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96593.1"
FT                   /translation="MIDEALFDAEEKMEKAVAVARDDLSTIRTGRANPGMFSRITIDYY
FT                   GAATPITQLASINVPEARLVVIKPYEANQLRAIETAIRNSDLGVNPTNDGALIRVAVPQ
FT                   LTEERRRELVKQAKHKGEEAKVSVRNIRRKAMEELHRIRKEGEAGEDEVGRAEKDLDKT
FT                   THQYVTQIDELVKHKEGELLEV"
FT   CDS             complement(23888..24673)
FT                   /transl_table=11
FT                   /gene="pyrH"
FT                   /locus_tag="Mb2907c"
FT                   /product="PROBABLE URIDYLATE KINASE PYRH (UK) (URIDINE
FT                   MONOPHOSPHATE KINASE) (UMP KINASE)"
FT                   /EC_number="2.7.4.-"
FT                   /note="Mb2907c, pyrH, len: 261 aa. Equivalent to Rv2883c,
FT                   len: 261 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 261 aa overlap). Probable pyrH,
FT                   uridylate kinase (EC 2.7.4.-), equivalent to
FT                   O33045|PYRH_MYCLE|ML1591|MLCB250.75 URIDYLATE KINASE from
FT                   Mycobacterium leprae (279 aa), FASTA scores: opt: 1437,
FT                   E(): 3.8e-81, (85.05% identity in 274 aa overlap). Also
FT                   highly similar to others e.g. O69913|PYRH from Streptomyces
FT                   coelicolor (253 aa), FASTA scores: opt: 1086, E(): 1.4e-59,
FT                   (68.9% identity in 251 aa overlap);
FT                   P74457|PYRH_SYNY3|SLL0144 from Synechocystis sp. strain PCC
FT                   6803 (260 aa), FASTA scores: opt: 851, E(): 4.1e-45,
FT                   (55.85% identity in 231 aa overlap);
FT                   P29464|PYRH_ECOLI|SMBA|B0171|Z0182|ECS0173 from strains K12
FT                   and O157:H7 (240 aa), FASTA scores: opt: 666, E(): 1.1e-35,
FT                   (45.7% identity in 232 aa overlap); etc."
FT                   /db_xref="GOA:P65930"
FT                   /db_xref="InterPro:IPR015963"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65930"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96594.1"
FT                   /translation="MTEPDVAGAPASKPEPASTGAASAAQLSGYSRVLLKLGGEMFGGG
FT                   QVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGMERTRSDYMGMLGT
FT                   VMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYF
FT                   STDTTAAQRALEIGADVVLMAKAVDGVFAEDPRVNPEAELLTAVSHREVLDRGLRVADA
FT                   TAFSLCMDNGMPILVFNLLTDGNIARAVRGEKIGTLVTT"
FT   CDS             24908..25666
FT                   /transl_table=11
FT                   /gene="Mb2908"
FT                   /locus_tag="Mb2908"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN"
FT                   /note="Mb2908, -, len: 252 aa. Equivalent to Rv2884, len:
FT                   252 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 252 aa overlap). Probable
FT                   transcriptional regulatory protein, highly similar to
FT                   others e.g. Q05943|GLNR_STRCO|SCD84.26c TRANSCRIPTIONAL
FT                   REGULATORY PROTEIN from Streptomyces coelicolor (267 aa),
FT                   FASTA scores: opt: 609, E(): 2.7e-34, (46.4% identity in
FT                   224 aa overlap); Q55733|SLL0396 REGULATORY COMPONENTS OF
FT                   SENSORY TRANSDUCTION SYSTEM from Synechocystis sp. strain
FT                   PCC 6803 (224 aa), FASTA scores: opt: 330, E(): 3e-15,
FT                   (31.8% identity in 217 aa overlap); Q9A4S3|CC2757
FT                   DNA-BINDING RESPONSE REGULATOR from Caulobacter crescentus
FT                   (223 aa), FASTA scores: opt: 311, E(): 6e-14, (30.3%
FT                   identity in 221 aa overlap); etc. Also highly similar to
FT                   O53830|Rv0818|MTV043.10 PUTATIVE REGULATORY PROTEIN from
FT                   Mycobacterium tuberculosis (255 aa), FASTA scores: opt:
FT                   665, E(): 3.8e-38, (47.6% identity in 227 aa overlap). THE
FT                   N-TERMINAL REGION IS SIMILAR TO THAT OF OTHER REGULATORY
FT                   COMPONENTS OF SENSORY TRANSDUCTION SYSTEMS."
FT                   /db_xref="GOA:Q7TXN2"
FT                   /db_xref="HSSP:1GXQ"
FT                   /db_xref="InterPro:IPR011991"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN2"
FT                   /protein_id="CAD96595.1"
FT                   /translation="MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSV
FT                   QRAPLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANFVAVD
FT                   GDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGTLQFGDLVLHPASYTASLGDRDLG
FT                   LTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRRLRAKLGAEHESM
FT                   IDTVRGVGYMAVTPPQPRWIISESILNRCK"
FT   repeat_region   complement(25681..27948)
FT                   /mobile_element="insertion sequence:IS1539"
FT                   /locus_tag="IS1539"
FT                   /note="IS1539, len: 2268 nt. Equivalent to IS1539, len:
FT                   2267 nt, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 2268 nt overlap)."
FT   CDS             complement(25745..27064)
FT                   /transl_table=11
FT                   /gene="Mb2909c"
FT                   /locus_tag="Mb2909c"
FT                   /product="PUTATIVE TRANSPOSASE"
FT                   /note="Mb2909c, -, len: 439 aa. Equivalent to Rv2885c, len:
FT                   460 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 437 aa overlap). Putative transposase
FT                   for IS1539. Contains PS00017 ATP/GTP-binding site motif A
FT                   (P-loop). REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   bovis, a single base insertion (*-c) leads to a truncation
FT                   resulting in a shorter product compared to its homolog in
FT                   Mycobacterium tuberculosis stain H37Rv (439 aa versus 460
FT                   aa)."
FT                   /db_xref="InterPro:IPR010095"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXN1"
FT                   /protein_id="CAD96596.1"
FT                   /translation="MMARLKVPEGWCVQAFRFTLNPTQTQAASLARHFGARRKAFNWTV
FT                   TALKADIKAWRADGTESAKPSLRVLRKRWNTVKDQVCVNAQTGQVWWPECSKEAYADGI
FT                   AGAVDAYWNWQSCRAGKRAGKTVGVPRFKKKGRDADRVCFTTGAMRVEPDRRHLTLPVI
FT                   GTIRTYENTRRVERLIAKGRARVLAITVRRNGTRLDASVRVLVQRPQQRRVALPDSRVG
FT                   VDVGVRRLATVADAEGTVLEQVPNPRPLDAALRGLRRVSRARSRCTKGSRRYCERTTEL
FT                   SRLHRRVNDVRTHHLHVLTTRLAKTHGRIVVEGLDAAGMLRQKGLPGARARRRALSDAA
FT                   LATPRRHLSYKTGWYGSSLVVADRWFPSSKTCHACRHVQDIGWDEIWQCDGCSITHQRD
FT                   DNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGWP"
FT   CDS             complement(27061..27948)
FT                   /transl_table=11
FT                   /gene="Mb2910c"
FT                   /locus_tag="Mb2910c"
FT                   /product="PROBABLE RESOLVASE"
FT                   /note="Mb2910c, -, len: 295 aa. Equivalent to Rv2886c, len:
FT                   295 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 295 aa overlap). Probable resolvase for
FT                   IS1539. Contains PS00213 Lipocalin signature."
FT                   /db_xref="GOA:P65046"
FT                   /db_xref="InterPro:IPR006119"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65046"
FT                   /protein_id="CAD96597.1"
FT                   /translation="MSRILTHVPGRTVNRSYALPALVGSAAGRLSGNHSHGREAYIALP
FT                   QWACSRQPSTPPLQTPGRINALWSLRPVLPMPGRGCQLLRLGGRWLSVVCCRNGSMNLV
FT                   VWAEGNGVARVIAYRWLRVGRLPVPARRVGRVILVDEPAGQPGRWGRTAVCARLSSADQ
FT                   KVDLDRQVVGVTAWATAEQIPVGKVVTEVGSALYGRRRTFLTLLGDPTVRRIVMKRRDR
FT                   LGRFGFECVQAVLAADGRELVVVDSADVDDDVVGDITEILTSICARLYGKRAAGNRAAR
FT                   AVAAAARAGGHEAR"
FT   CDS             27947..28366
FT                   /transl_table=11
FT                   /gene="Mb2911"
FT                   /locus_tag="Mb2911"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN"
FT                   /note="Mb2911, -, len: 139 aa. Equivalent to Rv2887, len:
FT                   139 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 139 aa overlap). Probable
FT                   transcriptional regulatory protein, highly similar to
FT                   Q9EX59|SC1A4.04 PUTATIVE MARR-FAMILY TRANSCRIPTIONAL
FT                   REGULATOR from Streptomyces coelicolor (151 aa), FASTA
FT                   scores: opt: 354, E(): 6.6e-16, (42.95% identity in 135 aa
FT                   overlap); and similar to others e.g. AAF97817|SLYA
FT                   TRANSCRIPTIONAL REGULATOR SLYA from Escherichia coli strain
FT                   EPEC 2348/69 (146 aa), FASTA scores: opt: 181, E(): 0.0001,
FT                   (27.25% identity in 132 aa overlap);
FT                   P55740|SLYA_ECOLI|AAG56631|B1642|Z2657|ECS2351
FT                   TRANSCRIPTIONAL REGULATOR SLYA from Escherichia coli
FT                   strains K12 and O157:H7 (146 aa), FASTA scores: opt: 177,
FT                   E(): 0.00018, (27.25% identity in 132 aa overlap) ; etc.
FT                   Contains probable helix-turn-helix motif at aa 50-71 (Score
FT                   1182, +3.21 SD)."
FT                   /db_xref="GOA:P67748"
FT                   /db_xref="InterPro:IPR011991"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67748"
FT                   /protein_id="CAD96598.1"
FT                   /translation="MGLADDAPLGYLLYRVGAVLRPEVSAALSPLGLTLPEFVCLRMLS
FT                   QSPGLSSAELARHASVTPQAMNTVLRKLEDAGAVARPASVSSGRSLPATLTARGRALAK
FT                   RAEAVVRAADARVLARLTAPQQREFKRMLEKLGSD"
FT   CDS             complement(28380..29801)
FT                   /transl_table=11
FT                   /gene="amiC"
FT                   /locus_tag="Mb2912c"
FT                   /product="PROBABLE AMIDASE AMIC (AMINOHYDROLASE)"
FT                   /EC_number="3.5.1.4"
FT                   /note="Mb2912c, amiC, len: 473 aa. Equivalent to Rv2888c,
FT                   len: 473 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 473 aa overlap). Probable amiC, amidase
FT                   (EC 3.5.1.4), equivalent to
FT                   O33040|AMI3_MYCLE|AMIC|ML1596|MLCB250.65 PUTATIVE AMIDASE
FT                   AMIC from Mycobacterium leprae (468 aa), FASTA scores: opt:
FT                   2361, E(): 4.2e-139, (76.7% identity in 468 aa overlap).
FT                   Also similar to others e.g. Q9A8N0|CC1323 PUTATIVE
FT                   6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE from Caulobacter
FT                   crescentus (521 aa), FASTA scores: opt: 925, E(): 7.4e-50,
FT                   (36.55% identity in 465 aa overlap);
FT                   O28325|YJ54_ARCFU|AF1954 PUTATIVE AMIDASE (EC 3.5.1.4) from
FT                   Archaeoglobus fulgidus (453 aa), FASTA scores: opt: 659,
FT                   E(): 2.2e-33, (31.1% identity in 460 aa overlap);
FT                   Q55424|AMID_SYNY3|SLL0828 PUTATIVE AMIDASE from
FT                   Synechocystis sp. strain PCC 6803 (506 aa), FASTA scores:
FT                   opt: 643, E(): 2.4e-32, (30.7% identity in 466 aa overlap);
FT                   etc. Also similar to
FT                   O05835|AMI1_MYCTU|AMIA2|Rv2363|MT2432|MTCY27.17c PUTATIVE
FT                   AMIDASE AMIA2 (484 aa), FASTA scores: opt: 656, E():
FT                   3.6e-33, (35.9% identity in 465 aa overlap); and
FT                   Q11056|AMI2_MYCTU|AMIB2|Rv1263|MT1301|MTCY50.19c PUTATIVE
FT                   AMIDASE from Mycobacterium tuberculosis (462 aa), FASTA
FT                   scores: opt: 650, E(): 8.2e-33, (33.45% identity in 472 aa
FT                   overlap). Contains PS00017 ATP/GTP-binding site motif A
FT                   (P-poop). BELONGS TO THE AMIDASE FAMILY."
FT                   /db_xref="GOA:P63495"
FT                   /db_xref="InterPro:IPR000120"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63495"
FT                   /protein_id="CAD96599.1"
FT                   /translation="MSRVHAFVDDALGDLDAVALADAIRSGRVGRADVVEAAIARAEAV
FT                   NPALNALAYAAFDVARDAAAMGTGQEAFFSGVPTFIKDNVDVAGQPSMHGTDAWEPYAA
FT                   VADSEITRVVLGTGLVSLGKTQLSEFGFSAVAEHPRLGPVRNPWNTDYTAGASSSGSGA
FT                   LVAAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRGRLPLEPEYRRLPVGIVANGVLTR
FT                   TVRDTAAFYREAERLWRNHQLPPVGDVTSPVKQRLRIAVVTRSVLREASPEVRQLTLKL
FT                   AGLLEELGHRVEHVDHPPAPASFVDDFVLYWGFLALAQVRSGRRTFGRTFDPTRLDELT
FT                   LGLARHTGRNLHRLPLAIMRLRMLRRRSVRFFGTYDVLLTPTVAEATPQVGYLAPTDYQ
FT                   TVLDRLSSWVVFTPVQNVTGVPAISLPLAQSADGMPVGMMLSADTGREALLLELAYELE
FT                   EARPWARIHAPNIAE"
FT   CDS             complement(29808..30623)
FT                   /transl_table=11
FT                   /gene="tsf"
FT                   /locus_tag="Mb2913c"
FT                   /product="PROBABLE ELONGATION FACTOR TSF (EF-TS)"
FT                   /note="Mb2913c, tsf, len: 271 aa. Equivalent to Rv2889c,
FT                   len: 271 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 271 aa overlap). Probable tsf,
FT                   elongation factor, equivalent to
FT                   O33039|EFTS_MYCLE|TSF|ML1597|MLCB250.64 ELONGATION FACTOR
FT                   from Mycobacterium leprae (276 aa), FASTA scores: opt:
FT                   1430, E(): 1.9e-80, (83.7% identity in 276 aa overlap).
FT                   Also highly similar to others e.g. Q9X5Z9|EFTS_STRRA|TSF
FT                   from Streptomyces ramocissimus (278 aa), FASTA scores: opt:
FT                   928, E(): 1.1e-49, (57.05% identity in 277 aa overlap);
FT                   O31213|EFTS_STRCO|TSF|SC2E1.42 from Streptomyces coelicolor
FT                   (278 aa), FASTA scores: opt: 927, E(): 1.3e-49, (56.3%
FT                   identity in 277 aa overlap); P80700|EFTS_BACSU|TSF from
FT                   Bacillus subtilis (292 aa), FASTA scores: opt: 650, E():
FT                   1.3e-32, (43.85% identity in 276 aa overlap); etc. Contains
FT                   PS01127 Elongation factor Ts signature 2. BELONGS TO THE
FT                   EF-TS FAMILY."
FT                   /db_xref="GOA:Q7TXN0"
FT                   /db_xref="InterPro:IPR018101"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXN0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96600.1"
FT                   /translation="MANFTAADVKRLRELTGAGMLACKNALAETDGDFDKAVEALRIKG
FT                   AKDVGKRAERATAEGLVAAKDGALIELNCETDFVAKNAEFQTLADQVVAAAAAAKPADV
FT                   DALKGASIGDKTVEQAIAELSAKIGEKLELRRVAIFDGTVEAYLHRRSADLPPAVGVLV
FT                   EYRGDDAAAAHAVALQIAALRARYLSRDDVPEDIVASERRIAEETARAEGKPEQALPKI
FT                   VEGRLNGFFKDAVLLEQASVSDNKKTVKALLDVAGVMVTRFVRFEVGQA"
FT   CDS             complement(30635..31498)
FT                   /transl_table=11
FT                   /gene="rpsB"
FT                   /locus_tag="Mb2914c"
FT                   /product="PROBABLE 30S RIBOSOMAL PROTEIN S2 RPSB"
FT                   /note="Mb2914c, rpsB, len: 287 aa. Equivalent to Rv2890c,
FT                   len: 287 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 287 aa overlap). Probable rpsB, 30s
FT                   ribosomal protein s2, equivalent to
FT                   O33038|RS2_MYCLE|RPSB|ML1598|MLCB250.63 30S RIBOSOMAL
FT                   PROTEIN S2 from Mycobacterium leprae (277 aa), FASTA
FT                   scores: opt: 1593, E(): 2.3e-93, (91.5% identity in 270 aa
FT                   overlap). Also highly similar to others e.g.
FT                   O31212|RS2_STRCO|RPSB|SC2E1.41 from Streptomyces coelicolor
FT                   (310 aa), FASTA scores: opt: 1302, E(): 6.1e-75, (70.6%
FT                   identity in 289 aa overlap); Q9KA63|RPSB|BH2427 from
FT                   Bacillus halodurans (244 aa), FASTA scores: opt: 991, E():
FT                   2.3e-55, (59.6% identity in 255 aa overlap);
FT                   P21464|RS2_BACSU|RPSB from Bacillus subtilis (245 aa),
FT                   FASTA scores: opt: 959, E(): 2.4e-53, (58.55% identity in
FT                   246 aa overlap); etc. Contains PS00962 Ribosomal protein S2
FT                   signature 1. BELONGS TO THE S2P FAMILY OF RIBOSOMAL
FT                   PROTEINS."
FT                   /db_xref="GOA:P66538"
FT                   /db_xref="InterPro:IPR018130"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66538"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96601.1"
FT                   /translation="MAVVTMKQLLDSGTHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQ
FT                   TLTFIDKAYEFVKETVAHGGSVLFVGTKKQAQESVAAEATRVGMPYVNQRWLGGMLTNF
FT                   STVHKRLQRLKELEAMEQTGGFEGRTKKEILGLTREKNKLERSLGGIRDMAKVPSAIWV
FT                   VDTNKEHIAVGEARKLGIPVIAILDTNCDPDEVDYPIPGNDDAIRSAALLTRVIASAVA
FT                   EGLQARAGLGRADGKPEAEAAEPLAEWEQELLASATASATPSATASTTALTDAPAGATE
FT                   PTTDAS"
FT   CDS             31782..32531
FT                   /transl_table=11
FT                   /gene="Mb2915"
FT                   /locus_tag="Mb2915"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2915, -, len: 249 aa. Equivalent to Rv2891, len:
FT                   249 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 249 aa overlap). Conserved hypothetical
FT                   protein, similar in N-terminus to O69910|SC2E1.40c
FT                   HYPOTHETICAL 22.8 KDA PROTEIN from Streptomyces coelicolor
FT                   (226 aa), FASTA scores: opt: 315, E(): 3.4e-11, (40.7%
FT                   identity in 145 aa overlap). C-terminus overlaps
FT                   neigbouring ORF."
FT                   /db_xref="InterPro:IPR016047"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65048"
FT                   /protein_id="CAD96602.1"
FT                   /translation="MAKSPARRCTAKVRRVLSRSVLILCWSLLGAAPAHADDSRLGWPL
FT                   RPPPAVVRQFDAASPNWNPGHRGVDLAGRPGQPVYAAGSATVVFAGLLAGRPVVSLAHP
FT                   GGLRTSYEPVVAQVRVGQPVSAPTVIGALAAGHPGCQAAACLHWGAMWGPASGANYVDP
FT                   LGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKSPKQGVFRGAAQG
FT                   GDIVARQPPGRWVCPSSAGGPIGWHRQ"
FT   CDS             complement(32310..33536)
FT                   /transl_table=11
FT                   /gene="PPE45"
FT                   /locus_tag="Mb2916c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb2916c, PPE45, len: 408 aa. Equivalent to Rv2892c,
FT                   len: 408 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 408 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PPE family, highly similar to
FT                   many e.g. O06386|Rv3621c|MTCY15C10.31|MTCY07H7B.01 from M.
FT                   tuberculosis (413 aa), FASTA scores: opt: 957, E():
FT                   6.2e-46, (44.7% identity in 423 aa overlap)."
FT                   /db_xref="GOA:P0A695"
FT                   /db_xref="InterPro:IPR000030"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A695"
FT                   /protein_id="CAD96603.1"
FT                   /translation="MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGY
FT                   RLAISELTGAYWAGPAAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMT
FT                   VPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAIATE
FT                   LTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQW
FT                   LAENLLGLTPDNRMTIVRLLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSW
FT                   GPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESIGGSVSAALGKGSSAGSLSVP
FT                   PDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLA
FT                   VMQRPPFAG"
FT   CDS             33936..34913
FT                   /transl_table=11
FT                   /gene="Mb2917"
FT                   /locus_tag="Mb2917"
FT                   /product="POSSIBLE OXIDOREDUCTASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2917, -, len: 325 aa. Equivalent to Rv2893, len:
FT                   325 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 325 aa overlap). Possible
FT                   oxidoreductase (EC 1.-.-.-), showing similarity with
FT                   various proteins and/or oxidoreductases e.g. Q9AE05|RIF11
FT                   eleventh protein in the rif biosynthetic gene cluster from
FT                   Amycolatopsis mediterranei (Nocardia mediterranei) (294
FT                   aa), FASTA scores: opt: 270, E(): 4.8e-10, (34.5% identity
FT                   in 313 aa overlap); O52567 REDUCTASE from Amycolatopsis
FT                   mediterranei (Nocardia mediterranei) (153 aa), FASTA
FT                   scores: opt: 251, E(): 5e-09, (42.4% identity in 125 aa
FT                   overlap); Q58929|MER|MJ1534 F420-DEPENDENT
FT                   METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (EC 1.5.99.-)
FT                   from Methanococcus jannaschii (331 aa), FASTA scores: opt:
FT                   249, E(): 1.2e-08, (29.7% identity in 283 aa overlap); etc.
FT                   Also some similarity with others proteins from
FT                   Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g.
FT                   P71844|Rv0791c|MTCY369.35c PUTATIVE OXIDOREDUCTASE (347
FT                   aa), FASTA scores: opt: 264, E(): 1.3e-09, (29.05% identity
FT                   in 272 aa overlap); and P96809|Rv0132|MTCI5.06c PUTATIVE
FT                   OXIDOREDUCTASE (360 aa), FASTA scores: opt: 260, E():
FT                   2.4e-09, (33.05% identity in 239 aa overlap)."
FT                   /db_xref="GOA:Q7TXM9"
FT                   /db_xref="InterPro:IPR019923"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96604.1"
FT                   /translation="MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAAGFDVLAF
FT                   PDHLVPSVSPFAGATAAAMATQRLHTGTLVLNNDFRHPVDTAREAAGVATLAEGRFELG
FT                   LGAGHRRSEYDAAGITFDSGATRVARLIESAHLIRALLDAEPVDFDGQHYRVHAEAGSL
FT                   VAPPKVRVPLLVGGNGTEVLRLGGRIADIVGLAGISHNRDATQVRFTHFDADGLADRIA
FT                   VVRHAAGDRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQVLESPFLLLGTHE
FT                   QMAEALAARQRRFGVSYWTVFDEWAGRASAMRDIAEVIALLRYG"
FT   CDS             complement(34910..35806)
FT                   /transl_table=11
FT                   /gene="xerC"
FT                   /locus_tag="Mb2918c"
FT                   /product="PROBABLE INTEGRASE/RECOMBINASE XERC"
FT                   /note="Mb2918c, xerC, len: 298 aa. Equivalent to Rv2894c,
FT                   len: 298 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 298 aa overlap). Probable xerC,
FT                   integrase/recombinase, equivalent to
FT                   Q9CBU0|XERC|ML1600|MLCB250.62 INTEGRASE/RECOMBINASE from
FT                   Mycobacterium leprae (297 aa), FASTA scores: opt: 1624,
FT                   E(): 2e-97, (85.15% identity in 296 aa overlap). Also
FT                   highly similar to others integrases/recombinases (generally
FT                   xerC and xerD) e.g. Q9HTS4|SSS|PA5280 SITE-SPECIFIC
FT                   RECOMBINASE from Pseudomonas aeruginosa (303 aa), FASTA
FT                   scores: opt: 660, E(): 3.2e-35, (41.8% identity in 299 aa
FT                   overlap); Q9HXQ6|XERD|PA3738 INTEGRASE/RECOMBINASE from
FT                   Pseudomonas aeruginosa (298 aa), FASTA scores: opt: 656,
FT                   E(): 5.7e-35, (40.05% identity in 297 aa overlap);
FT                   Q9KCP0|BH1529 INTEGRASE/RECOMBINASE from Bacillus
FT                   halodurans (299 aa), FASTA scores: opt: 645, E(): 2.9e-34,
FT                   (37.35% identity in 300 aa overlap); etc. Also similar to
FT                   O33200|Rv1701|MTCI125.23 INTEGRASE/RECOMBINASE from
FT                   Mycobacterium tuberculosis (311 aa), FASTA scores: opt:
FT                   646, E(): 2.6e-34, (43.1% identity in 304 aa overlap).
FT                   BELONGS TO THE 'PHAGE' INTEGRASE FAMILY."
FT                   /db_xref="GOA:P67629"
FT                   /db_xref="HSSP:1A0P"
FT                   /db_xref="InterPro:IPR011931"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67629"
FT                   /protein_id="CAD96605.1"
FT                   /translation="MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLD
FT                   ALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARR
FT                   TLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDT
FT                   GHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVR
FT                   QARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTH
FT                   VAVARLRAVHERAHPRA"
FT   CDS             complement(35897..36748)
FT                   /transl_table=11
FT                   /gene="viuB"
FT                   /locus_tag="Mb2919c"
FT                   /product="POSSIBLE MYCOBACTIN UTILIZATION PROTEIN VIUB"
FT                   /note="Mb2919c, viuB, len: 283 aa. Equivalent to Rv2895c,
FT                   len: 283 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 283 aa overlap). Possible viuB,
FT                   mycobactin utilization protein, highly similar to
FT                   Q9RJ78|SCI41.06 HYPOTHETICAL 31.5 KDA PROTEIN from
FT                   Streptomyces coelicolor (280 aa), FASTA scores: opt: 639,
FT                   E(): 5.1e-32, (46.3% identity in 285 aa overlap); and
FT                   similar to other proteins e.g. Q9F641|MXCB protein of the
FT                   biosynthetic gene cluster of the myxochelin-type iron
FT                   chelator from Stigmatella aurantiaca (270 aa), FASTA
FT                   scores: opt: 417, E(): 2.2e-18, (34.2% identity in 263 aa
FT                   overlap); Q56646|VIUB_VIBCH|VC2210 VIBRIOBACTIN UTILIZATION
FT                   PROTEIN from Vibrio cholerae (271 aa), FASTA scores: opt:
FT                   395, E(): 5.1e-17, (31.0% identity in 274 aa overlap);
FT                   Q56743|VIUB_VIBVU VULNIBACTIN UTILIZATION PROTEIN V from
FT                   Vibrio vulnificus (271 aa), FASTA scores: opt: 390, E():
FT                   1e-16, (33.95% identity in 274 aa overlap); etc. Equivalent
FT                   to AAK47289 from Mycobacterium tuberculosis strain CDC1551
FT                   (321 aa) but shorter 38 aa."
FT                   /db_xref="GOA:P65050"
FT                   /db_xref="InterPro:IPR007037"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65050"
FT                   /protein_id="CAD96606.1"
FT                   /translation="MAGRPLHAFEVVATRHLAPHMVRVVLGGSGFDTFVPSDFTDSYIK
FT                   LVFVDDDVDVGRLPRPLTLDSFADLPTAKRPPVRTMTVRHVDAAAREIAVDIVLHGEHG
FT                   VAGPWAAGAQRGQPIYLMGPGGAYAPDPAADWHLLAGDESAIPAIAAALEALPPDAIGR
FT                   AFIEVAGPDDEIGLTAPDAVEVNWVYRGGRADLVPEDRAGDHAPLIEAVTTTAWLPGQV
FT                   HVFIHGEAQAVMHNLRPYVRNERGVDAKWASSISGYWRRGRTEEMFRKWKKELAEAEAG
FT                   TH"
FT   CDS             complement(36781..37950)
FT                   /transl_table=11
FT                   /gene="Mb2920c"
FT                   /locus_tag="Mb2920c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2920c, -, len: 389 aa. Equivalent to Rv2896c, len:
FT                   389 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.5% identity in 389 aa overlap). Conserved hypothetical
FT                   protein, similar to others proteins e.g. Q9ZJ08|FIR2 from
FT                   Rhodococcus fascians (293 aa), FASTA scores: opt: 663, E():
FT                   3.3e-32, (43.7% identity in 286 aa overlap);
FT                   O69892|SC2E1.21 HYPOTHETICAL 37.9 KDA PROTEIN from
FT                   Streptomyces coelicolor (382 aa), FASTA scores: opt: 600,
FT                   E(): 2.2e-28, (46.45% identity in 267 aa overlap);
FT                   Q9JWZ4|DPRA|NMA0158 DPRA HOMOLOG from Neisseria
FT                   meningitidis (serogroup A) (395 aa), FASTA scores: opt:
FT                   495, E(): 4.1e-22, (34.6% identity in 347 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:Q7TXM8"
FT                   /db_xref="InterPro:IPR003488"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM8"
FT                   /protein_id="CAD96607.1"
FT                   /translation="MIDPTARAWAYLSRVAEPPCAQLAALVRCVGPVEAADRVRRGQVG
FT                   NELAQHTGARRGIDRAADDLELLMRRGGRLITPDDDEWPVLAFAAFSGAGARARPCGHS
FT                   PLVLWALGPARLDEVAPRAAAVVGTRAATAYGEHVAADLAAGLAERDVAVVSGGAYGID
FT                   GAAHRAALDSEGITVAVLAGGFDIPYPAGHSALLHRIAQHGVLFTEYPPGVRPARHRFL
FT                   TRNRLVAAVARAAVVVEAGLRSGAANTAAWARALGRVVAAVPGPVTSSASAGCHTLLRH
FT                   GAELVTRADDIVEFVGHIGELAGDEPRPGAALDVLSEAERQVYEALPGRGAATIDEIAV
FT                   GSGLLPAQVLGPLAILEVAGLAECRDGRWRILRAGAGQAAAKGAAARLV"
FT   CDS             complement(37947..39458)
FT                   /transl_table=11
FT                   /gene="Mb2921c"
FT                   /locus_tag="Mb2921c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2921c, -, len: 503 aa. Equivalent to Rv2897c, len:
FT                   503 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 503 aa overlap). Conserved hypothetical
FT                   protein, possibly Mg-chelatase, highly similar to
FT                   hypothetical proteins and chelatases e.g. Q9RTV0|DR1656
FT                   MG(2+) CHELATASE FAMILY PROTEIN from Deinococcus
FT                   radiodurans (519 aa), FASTA scores: opt: 1333, E():
FT                   3.6e-68, (46.55% identity in 505 aa overlap);Q55372|SLR0904
FT                   HYPOTHETICAL 55.1 KDA PROTEIN from Synechocystis sp. strain
FT                   PCC 6803 (509 aa), FASTA scores: opt: 1271, E(): 1.2e-64,
FT                   (42.65% identity in 504 aa overlap); Q9HTR4|PA5290
FT                   HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (497 aa),
FT                   FASTA scores: opt: 1248, E(): 2.3e-63, (45.9% identity in
FT                   503 aa overlap); Q9K0Z6|COMM|NMB0405 COMPETENCE PROTEIN
FT                   (MG-CHELATASE) from Neisseria meningitidis (serogroup B),
FT                   FASTA scores: opt: 1229, E(): 2.8e-62, (43.2% identity in
FT                   509 aa overlap); etc. Contains PS00017 ATP/GTP-binding site
FT                   motif A (P-loop)."
FT                   /db_xref="GOA:P68908"
FT                   /db_xref="InterPro:IPR000523"
FT                   /db_xref="UniProtKB/Swiss-Prot:P68908"
FT                   /protein_id="CAD96608.1"
FT                   /translation="MALGRAFSVAVRGLDGEIVEIEADITSGLPGVHLVGLPDAALQES
FT                   RDRVRAAVTNCGNSWPMARLTLALSPATLPKMGSVYDIALAAAVLSAQQKKPWERLENT
FT                   LLLGELSLDGRVRPVRGVLPAVLAAKRDGWPAVVVPADNLPEASLVDGIDVRGVRTLGQ
FT                   LQSWLRGSTGLAGRITTADTTPESAADLADVVGQSQARFAVEVAAAGAHHLMLTGPPGV
FT                   GKTMLAQRLPGLLPSLSGSESLEVTAIHSVAGLLSGDTPLITRPPFVAPHHSSSVAALV
FT                   GGGSGMARPGAVSRAHRGVLFLDECAEISLSALEALRTPLEDGEIRLARRDGVACYPAR
FT                   FQLVLAANPCPCAPADPQDCICAAATKRRYLGKLSGPLLDRVDLRVQMHRLRAGAFSAA
FT                   DGESTSQVRQRVALAREAAAQRWRPHGFRTNAEVSGPLLRRKFRPSSAAMLPLRTALDR
FT                   GLLSIRGVDRTLRVAWSLADLAGRTSPGIDEVAAALSFRQTGARR"
FT   CDS             complement(39458..39844)
FT                   /transl_table=11
FT                   /gene="Mb2922c"
FT                   /locus_tag="Mb2922c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2922c, -, len: 128 aa. Equivalent to Rv2898c, len:
FT                   128 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 128 aa overlap). Conserved hypothetical
FT                   protein, highly similar to
FT                   O33024|YS98_MYCLE|ML1607|MLCB250.49 HYPOTHETICAL 11.0 KDA
FT                   PROTEIN from Mycobacterium leprae (96 aa), FASTA scores:
FT                   opt: 318, E(): 2.3e-16, (58.35% identity in 96 aa overlap).
FT                   Also similar to other hypothetical proteins e.g.
FT                   O69890|YE19_STRCO|SC2E1.19 from Streptomyces coelicolor
FT                   (130 aa), FASTA scores: opt: 253, E(): 1.7e-11, (39.65%
FT                   identity in 121 aa overlap); Q9HVZ1|PA4424 from Pseudomonas
FT                   aeruginosa (125 aa), FASTA scores: opt: 234, E(): 4.2e-10,
FT                   (40.85% identity in 115 aa overlap); O86871 from
FT                   Streptomyces lividans (85 aa), FASTA scores: opt: 224, E():
FT                   1.8e-09, (46.45% identity in 84 aa overlap); etc.
FT                   Equivalent to AAK47292 from Mycobacterium tuberculosis
FT                   strain CDC1551 (141 aa) but shorter 13 aa."
FT                   /db_xref="GOA:P67231"
FT                   /db_xref="InterPro:IPR003509"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67231"
FT                   /protein_id="CAD96609.1"
FT                   /translation="MTTLKTMTRVQLGAMGEALAVDYLTSMGLRILNRNWRCRYGELDV
FT                   IACDAATRTVVFVEVKTRTGDGYGGLAHAVTERKVRRLRRLAGLWLADQEERWAAVRID
FT                   VIGVRVGPKNSGRTPELTHLQGIG"
FT   CDS             complement(40092..40922)
FT                   /transl_table=11
FT                   /gene="fdhD"
FT                   /locus_tag="Mb2923c"
FT                   /product="POSSIBLE FDHD PROTEIN"
FT                   /note="Mb2923c, fdhD, len: 276 aa. Equivalent to Rv2899c,
FT                   len: 276 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 276 aa overlap). Possible fdhD protein,
FT                   highly similar to other bacterial fdhd proteins e.g.
FT                   Q9ZBW0|FDHD_STRCO|SC4B5.08c from Streptomyces coelicolor
FT                   (282 aa), FASTA scores: opt: 1032, E(): 3.6e-59, (59.0%
FT                   identity in 278 aa overlap); BAB59387|TVG0258796 from
FT                   Thermoplasma volcanium (279 aa), FASTA scores: opt: 536,
FT                   E(): 3.4e-27, (38.65% identity in 282 aa overlap);
FT                   Q9HL17|FDHD_THEAC|TA0423 from Thermoplasma acidophilum (282
FT                   aa), FASTA scores: opt: 529, E(): 9.6e-27, (38.8% identity
FT                   in 281 aa overlap); P32177|FDHD_ECOLI FDHD PROTEIN from
FT                   Escherichia coli strain K12 (277 aa), FASTA scores: opt:
FT                   297, E(): 8.6e-12, (33.35% identity in 261 aa overlap);
FT                   etc. BELONGS TO THE FDHD FAMILY."
FT                   /db_xref="GOA:P64119"
FT                   /db_xref="InterPro:IPR003786"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64119"
FT                   /protein_id="CAD96610.1"
FT                   /translation="MGYATAHRRVRHLSADQVITRPETLAVEEPLEIRVNGTPVTVTMR
FT                   TPGSDFELVQGFLLAEGVVAHREDVLTVSYCGRRVEGNATGASTYNVLDVALAPGVKPP
FT                   DVDVTRTFYTTSSCGVCGKASLQAVSQVSRFAPGGDPATVAADTLKAMPDQLRRAQKVF
FT                   ARTGGLHAAALFGVDGAMLAVREDIGRHNAVDKVIGWAFERDRIPLGASVLLVSGRASF
FT                   ELTQKALMAGIPVLAAVSAPSSLAVSLADASGITLVAFLRGDSMNVYTRADRIT"
FT   CDS             complement(40922..43261)
FT                   /transl_table=11
FT                   /gene="fdhF"
FT                   /locus_tag="Mb2924c"
FT                   /product="POSSIBLE FORMATE DEHYDROGENASE H FDHF
FT                   (FORMATE-HYDROGEN-LYASE-LINKED, SELENOCYSTEINE-CONTAINING
FT                   POLYPEPTIDE) (FORMATE DEHYDROGENASE-H ALPHA SUBUNIT)
FT                   (FDH-H)"
FT                   /EC_number="1.2.1.2"
FT                   /note="Mb2924c, fdhF, len: 779 aa. Equivalent to Rv2900c,
FT                   len: 779 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 779 aa overlap). Possible fdhF, formate
FT                   dehydrogenase (EC 1.2.1.2), highly similar to others
FT                   formate dehydrogenases and prokaryotic
FT                   molybdopterin-containing oxidoreductases e.g.
FT                   Q9S2J9|SC7H2.18 PUTATIVE FORMATE DEHYDROGENASE from
FT                   Streptomyces coelicolor (759 aa), FASTA scores: opt: 3038,
FT                   E(): 2.7e-180, (59.7% identity in 767 aa overlap);
FT                   Q9HU08|PA5181 PROBABLE OXIDOREDUCTASE from Pseudomonas
FT                   aeruginosa (773 aa), FASTA scores: opt: 2560, E():
FT                   1.1e-150, (53.2% identity in 761 aa overlap); P78160
FT                   FORMATE DEHYDROGENASE A CHAIN (EC 1.2.1.2) (FRAGMENT) from
FT                   Escherichia coli strain K12 (740 aa), FASTA scores: opt:
FT                   2002, E(): 3.7e-116, (43.1% identity in 733 aa overlap);
FT                   P07658|FDHF_ECOLI|P78137|B4079 FORMATE DEHYDROGENASE from
FT                   Escherichia coli strain K12 (715 aa), FASTA scores: opt:
FT                   305, E(): 5.6e-13, (25.5% identity in 748 aa overlap); etc.
FT                   BELONGS TO THE PROKARYOTIC MOLYBDOPTERIN-CONTAINING
FT                   OXIDOREDUCTASE FAMILY."
FT                   /db_xref="GOA:P65409"
FT                   /db_xref="InterPro:IPR006657"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65409"
FT                   /protein_id="CAD96611.1"
FT                   /translation="MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSL
FT                   QRGMQQMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEATKR
FT                   TVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAEQLN
FT                   GLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGK
FT                   GSVTIGDVEHADLIVIAGQNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDP
FT                   QKVNGVVGHGIPIADEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAG
FT                   FDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIG
FT                   EVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRA
FT                   HGFDTVAAIRAMRDGRVSVFMGMGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHL
FT                   VHGATALILPTLGRTDRDTRNGRKQLVSVEDSMSMVHLSRGSLHPPSDQVRSEVQIICQ
FT                   LARALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDARE
FT                   FRTSTGKANFAVNPLQWVPVPPGRLVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFI
FT                   NPADIETFGLTAGDRVDLVSEWTDGQGGLQERRAKDFLVVAYSTPVGNAAAYYPETNPL
FT                   VPLDHTAAQSNTPVSKAIIVRLEPTA"
FT   CDS             complement(43319..43624)
FT                   /transl_table=11
FT                   /gene="Mb2925c"
FT                   /locus_tag="Mb2925c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2925c, -, len: 101 aa. Equivalent to Rv2901c, len:
FT                   101 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 101 aa overlap). Conserved hypothetical
FT                   protein, very equivalent to O33023|ML1610|MLCB250.41
FT                   HYPOTHETICAL 12.3 KDA PROTEIN from Mycobacterium leprae
FT                   (101 aa), FASTA scores: opt: 658, E(): 2.6e-43, (99.0%
FT                   identity in 101 aa overlap). Also highly similar to
FT                   O69889|SC2E1.18 HYPOTHETICAL PROTEIN from Streptomyces
FT                   coelicolor and Streptomyces lividans (102 aa), FASTA
FT                   scores: opt: 515, E(): 2.2e-32, (75.0% identity in 100 aa
FT                   overlap)."
FT                   /db_xref="InterPro:IPR019592"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65052"
FT                   /protein_id="CAD96612.1"
FT                   /translation="MSAEDLEKYETEMELSLYREYKDIVGQFSYVVETERRFYLANSVE
FT                   MVPRNTDGEVYFELRLADAWVWDMYRPARFVKQVRVVTFKDVNIEEVEKPELRLPE"
FT   CDS             complement(43678..44472)
FT                   /transl_table=11
FT                   /gene="rnhB"
FT                   /locus_tag="Mb2926c"
FT                   /product="PROBABLE RIBONUCLEASE HII PROTEIN RNHB (RNASE
FT                   HII)"
FT                   /EC_number="3.1.26.4"
FT                   /note="Mb2926c, rnhB, len: 264 aa. Equivalent to Rv2902c,
FT                   len: 264 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 264 aa overlap). Probable rnhB,
FT                   ribonuclease HII (EC 3.1.26.4), equivalent to
FT                   O33022|RNH2_MYCLE|RNHB|ML1611|MLCB250.40 RIBONUCLEASE HII
FT                   from Mycobacterium leprae (240 aa), FASTA scores: opt:
FT                   1242, E(): 6.9e-72, (76.75% identity in 245 aa overlap).
FT                   Also similar (but longer ~20 aa) to others e.g.
FT                   Q9HXY9|RNHB|PA3642 RIBONUCLEASE HII from Pseudomonas
FT                   aeruginosa (201 aa), FASTA scores: opt: 572, E(): 3.1e-29,
FT                   (52.7% identity in 184 aa overlap);
FT                   Q9PEI7|RNH2_XYLFA|RNHB|XF1041 RIBONUCLEASE HII from Xylella
FT                   fastidiosa (234 aa), FASTA scores: opt: 556, E(): 3.6e-28,
FT                   (50.25% identity in 185 aa overlap);
FT                   P10442|RNH2_ECOLI|RNHB|B0183 RIBONUCLEASE HII from
FT                   Escherichia coli strain K-12 (213 aa), FASTA scores: opt:
FT                   519, E(): 7.4e-26, (48.65% identity in 183 aa overlap);
FT                   etc. BELONGS TO THE RNASE HII FAMILY. COFACTOR: MANGANESE
FT                   (BY SIMILARITY)."
FT                   /db_xref="GOA:Q7TXM7"
FT                   /db_xref="InterPro:IPR001352"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXM7"
FT                   /protein_id="CAD96613.1"
FT                   /translation="MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGA
FT                   CAGPLVVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPSAEVD
FT                   RHGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGGDAAAACIAAASVL
FT                   AKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYSFINVRRVASGS
FT                   NTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT"
FT   CDS             complement(44486..45370)
FT                   /transl_table=11
FT                   /gene="lepB"
FT                   /locus_tag="Mb2927c"
FT                   /product="PROBABLE SIGNAL PEPTIDASE I LEPB (SPASE I)
FT                   (LEADER PEPTIDASE I)."
FT                   /EC_number="3.4.21.89"
FT                   /note="Mb2927c, lepB, len: 294 aa. Equivalent to Rv2903c,
FT                   len: 294 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 294 aa overlap). Probable lepB, signal
FT                   peptidase I (EC 3.4.21.89) (TYPE II MEMBRANE PROTEIN) (see
FT                   first citation below), equivalent to
FT                   O33021|LEP_MYCLE|ML1612|MLCB250.39 PROBABLE SIGNAL
FT                   PEPTIDASE I from Mycobacterium leprae (289 aa), FASTA
FT                   scores: opt: 1335, E(): 1.8e-77, (69.75% identity in 301 aa
FT                   overlap). Also similar to many e.g. O86869|SIPX SIGNAL
FT                   PEPTIDASE I from Streptomyces lividans (320 aa), FASTA
FT                   scores: opt: 474, E(): 1e-22, (43.55% identity in 248 aa
FT                   overlap); O69884|SIP1|SIPW PUTATIVE SIGNAL PEPTIDASE I from
FT                   Streptomyces coelicolor and Streptomyces lividans (259 aa),
FT                   FASTA scores: opt: 226, E(): 5e-07, (36.0% identity in 214
FT                   aa overlap); P42668|LEP_BACLI|SIP SIGNAL PEPTIDASE I from
FT                   Bacillus licheniformis (186 aa), FASTA scores: opt: 218,
FT                   E(): 1.3e-06, (34.5% identity in 194 aa overlap); etc.
FT                   Contains PS00501 Signal peptidases I serine active site,and
FT                   PS00761 Signal peptidases I signature 3. BELONGS TO
FT                   PEPTIDASE FAMILY S26; ALSO KNOWN AS TYPE I LEADER PEPTIDASE
FT                   FAMILY."
FT                   /db_xref="GOA:Q7TXM6"
FT                   /db_xref="HSSP:1B12"
FT                   /db_xref="InterPro:IPR019759"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96614.1"
FT                   /translation="MTETTDSPSERQPGPAEPELSSRDPDIAGQVFDAAPFDAAPDADS
FT                   EGDSKAAKTDEPRPAKRSTLREFAVLAVIAVVLYYVMLTFVARPYLIPSESMEPTLHGC
FT                   STCVGDRIMVDKLSYRFGSPQPGDVIVFRGPPSWNVGYKSIRSHNVAVRWVQNALSFIG
FT                   FVPPDENDLVKRVIAVGGQTVQCRSDTGLTVNGRPLKEPYLDPATMMADPSIYPCLGSE
FT                   FGPVTVPPGRVWVMGDNRTHSADSRAHCPLLCTNDPLPGTVPVANVIGKARLIVWPPSR
FT                   WGVVRSVNPQQGR"
FT   CDS             complement(45428..45769)
FT                   /transl_table=11
FT                   /gene="rplS"
FT                   /locus_tag="Mb2928c"
FT                   /product="PROBABLE 50S RIBOSOMAL PROTEIN L19 RPLS"
FT                   /note="Mb2928c, rplS, len: 113 aa. Equivalent to Rv2904c,
FT                   len: 113 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 113 aa overlap). Probable rplS, 50S
FT                   ribosomal protein L19, equivalent to O33020|RL19_MYCLE 50S
FT                   RIBOSOMAL PROTEIN L19 from Mycobacterium leprae (113 aa),
FT                   FASTA scores: opt: 702, E(): 1.4e-45, (93.8% identity in
FT                   113 aa overlap). Also highly similar to others e.g.
FT                   O69883|RL19_STRCO from Streptomyces coelicolor (116 aa),
FT                   FASTA scores: opt: 571, E(): 9.5e-36, (77.25% identity in
FT                   110 aa overlap); O31742|RL19_BACSU from Bacillus subtilis
FT                   (115 aa), FASTA scores: opt: 523, E(): 3.8e-32, (72.9%
FT                   identity in 107 aa overlap); RL19_BACST|P30529 from
FT                   Bacillus stearothermophilus (116 aa), FASTA scores: opt:
FT                   518, E(): 9.1e-32, (71.7% identity in 106 aa overlap); etc.
FT                   BELONGS TO THE L19P FAMILY OF RIBOSOMAL PROTEINS."
FT                   /db_xref="GOA:P66081"
FT                   /db_xref="InterPro:IPR018257"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66081"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96615.1"
FT                   /translation="MNRLDFVDKPSLRDDIPAFNPGDTINVHVKVIEGAKERLQVFKGV
FT                   VIRRQGGGIRETFTVRKESYGVGVERTFPVHSPNIDHIEVVTRGDVRRAKLYYLRELRG
FT                   KKAKIKEKR"
FT   CDS             46144..47088
FT                   /transl_table=11
FT                   /gene="lppW"
FT                   /locus_tag="Mb2929"
FT                   /product="PROBABLE CONSERVED ALANINE RICH LIPOPROTEIN LPPW"
FT                   /note="Mb2929, lppW, len: 314 aa. Equivalent to Rv2905,
FT                   len: 314 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 314 aa overlap). Probable lppW,
FT                   conserved ala-rich lipoprotein, with slight similarity to
FT                   beta-lactamases and hypothetical proteins e.g.
FT                   Q9S1P7|SCJ9A.23 HYPOTHETICAL 36.3 KDA PROTEIN from
FT                   Streptomyces coelicolor (336 aa), FASTA scores: opt: 222,
FT                   E(): 2.8e-06, (25.5% identity in 298 aa overlap);
FT                   O69914|SC3C8.01 PUTATIVE SECRETED PROTEIN from Streptomyces
FT                   coelicolor (302 aa), FASTA scores: opt: 201, E(): 5.1e-05,
FT                   (24.9% identity in 257 aa overlap); P14559|BLAC_STRAL
FT                   BETA-LACTAMASE PRECURSOR from Streptomyces albus G (314
FT                   aa), FASTA scores: opt: 113, E(): 3.3, (25.2% identity in
FT                   278 aa overlap); etc. Has signal peptide and appropriately
FT                   positioned prokaryotic lipoprotein lipid attachment site:
FT                   ATTACHED TO THE MEMBRANE BY A LIPID ANCHOR (POTENTIAL)."
FT                   /db_xref="GOA:P65305"
FT                   /db_xref="InterPro:IPR001466"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65305"
FT                   /protein_id="CAD96616.1"
FT                   /translation="MRARPLTLLTALAAVTLVVVAGCEARVEAEAYSAADRISSRPQAR
FT                   PQPQPVELLLRAITPPRAPAASPNVGFGELPTRVRQATDEAAAMGATLSVAVLDRATGQ
FT                   LVSNGNTQIIATASVAKLFIADDLLLAEAEGKVTLSPEDHHALDVMLQSSDDGAAERFW
FT                   SQDGGNAVVTQVARRYGLRSTAPPSDGRWWNTISSAPDLIRYYDMLLDGSGGLPLDRAA
FT                   VIIADLAQSTPTGIDGYPQRFGIPDGLYAEPVAVKQGWMCCIGSSWMHLSTGVIGPERR
FT                   YIMVIESLQPADDATARATITQAVRTMFPNGRI"
FT   CDS             complement(47181..47873)
FT                   /transl_table=11
FT                   /gene="trmD"
FT                   /locus_tag="Mb2930c"
FT                   /product="PROBABLE TRNA (GUANINE-N1)-METHYLTRANSFERASE TRMD
FT                   (M1G-METHYLTRANSFERASE) (TRNA [GM37] METHYLTRANSFERASE)"
FT                   /EC_number="2.1.1.31"
FT                   /note="Mb2930c, trmD, len: 230 aa. Equivalent to Rv2906c,
FT                   len: 230 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 230 aa overlap). Probable trmD, tRNA
FT                   m1G methyltransferase (EC 2.1.1.31), equivalent to
FT                   O33017|TRMD_MYCLE from Mycobacterium leprae (238 aa), FASTA
FT                   scores: opt: 1363, E(): 8.1e-86, (87.2% identity in 227 aa
FT                   overlap). Also highly similar to others e.g.
FT                   O69882|TRMD_STRCO from Streptomyces coelicolor and S.
FT                   lividans (277 aa), FASTA scores: opt: 841, E(): 4.5e-50,
FT                   (55.55% identity in 234 aa overlap); Q9A0B6 from
FT                   Streptococcus pyogenes (243 aa), FASTA scores: opt: 698,
FT                   E(): 2.5e-40, (47.6% identity in 227 aa overlap);
FT                   P07020|TRMD_ECOLI|TRMD|B2607|Z3901|ECS3470 from Escherichia
FT                   coli strain O157:H7 (255 aa), FASTA scores: opt: 573, E():
FT                   3.8e-33, (42.1% identity in 228 aa overlap); etc. BELONGS
FT                   TO THE RNA METHYLTRANSFERASE TRMD FAMILY."
FT                   /db_xref="GOA:P66969"
FT                   /db_xref="HSSP:1UAJ"
FT                   /db_xref="InterPro:IPR002649"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66969"
FT                   /protein_id="CAD96617.1"
FT                   /translation="MRIDIVTIFPACLDPLRQSLPGKAIESGLVDLNVHDLRRWTHDVH
FT                   HSVDDAPYGGGPGMVMKAPVWGEALDEICSSETLLIVPTPAGVLFTQATAQRWTTESHL
FT                   VFACGRYEGIDQRVVQDAARRMRVEEVSIGDYVLPGGESAAVVMVEAVLRLLAGVLGNP
FT                   ASHQDDSHSTGLDGLLEGPSYTRPASWRGLDVPEVLLSGDHARIAAWRREVSLQRTRER
FT                   RPDLSHPD"
FT   CDS             complement(47877..48407)
FT                   /transl_table=11
FT                   /gene="rimM"
FT                   /locus_tag="Mb2931c"
FT                   /product="PROBABLE 16S RRNA PROCESSING PROTEIN RIMM"
FT                   /note="Mb2931c, rimM, len: 176 aa. Equivalent to Rv2907c,
FT                   len: 176 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 176 aa overlap). Probable rimM, 16S
FT                   rRNA processing protein, equivalent to O33016|RIMM_MYCLE
FT                   PROBABLE 16S RRNA PROCESSING protein from Mycobacterium
FT                   leprae (179 aa), FASTA scores: opt: 797, E(): 2.4e-46,
FT                   (73.15% identity in 175 aa overlap). Also highly similar to
FT                   others e.g. O69881|RIMM_STRCO from Streptomyces coelicolor
FT                   (188 aa), FASTA scores: opt: 485, E(): 2.3e-25, (48.85%
FT                   identity in 176 aa overlap); Q9KA14|RIMM_BACHD from
FT                   Bacillus halodurans (173 aa), FASTA scores: opt: 289, E():
FT                   3.2e-12, (30.65% identity in 173 aa overlap);
FT                   P21504|RIMM_ECOLI|RIMM|B2608 from Escherichia coli strain
FT                   K12 (182 aa), FASTA scores: opt: 237, E(): 1e-08, (29.4%
FT                   identity in 177 aa overlap). BELONGS TO THE RIMM FAMILY."
FT                   /db_xref="GOA:P66654"
FT                   /db_xref="InterPro:IPR002676"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66654"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96618.1"
FT                   /translation="MELVVGRVVKSHGVTGEVVVEIRTDDPADRFAPGTRLRAKGPFDG
FT                   GAEGSAVSYVIESVRQHGGRLLVRLAGVADRDAADALRGSLFVIDADDLPPIDEPDTYY
FT                   DHQLVGLMVQTATGEGVGVVTEVVHTAAGELLAVKRDSDEVLVPFVRAIVTSVSLDDGI
FT                   VEIDPPHGLLNLE"
FT   CDS             complement(48421..48663)
FT                   /transl_table=11
FT                   /gene="Mb2932c"
FT                   /locus_tag="Mb2932c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2932c, -, len: 80 aa. Equivalent to Rv2908c, len:
FT                   80 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 80 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O33015|YT08_MYCLE from Mycobacterium
FT                   leprae (80 aa), FASTA scores: opt: 492, E(): 3.1e-29,
FT                   (93.75% identity in 80 aa overlap). Also highly similar to
FT                   others e.g. O69880|YE09_STRCO from Streptomyces coelicolor
FT                   (79 aa), FASTA scores: opt: 356, E(): 3e-19, (71.6%
FT                   identity in 74 aa overlap); Q9KA12|BH2482 PROTEIN from
FT                   Bacillus halodurans (76 aa), FASTA scores: opt: 220, E():
FT                   2.9e-09, (48.6% identity in 72 aa overlap);
FT                   O31738|YLQC_BACSU HYPOTHETICAL 9.1 KDA PROTEIN from
FT                   Bacillus subtilis (81 aa), FASTA scores: opt: 172, E():
FT                   1e-05, (39.2% identity in 74 aa overlap); etc. BELONGS TO
FT                   THE UPF0109 FAMILY."
FT                   /db_xref="GOA:P67237"
FT                   /db_xref="InterPro:IPR004088"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67237"
FT                   /protein_id="CAD96619.1"
FT                   /translation="MSAVVVDAVEHLVRGIVDNPDDVRVDLITSRRGRTVEVHVHPDDL
FT                   GKVIGRGGRTATALRTLVAGIGGRGIRVDVVDTDQ"
FT   CDS             complement(48671..49159)
FT                   /transl_table=11
FT                   /gene="rpsP"
FT                   /locus_tag="Mb2933c"
FT                   /product="PROBABLE 30S RIBOSOMAL PROTEIN S16 RPSP"
FT                   /note="Mb2933c, rpsP, len: 162 aa. Equivalent to Rv2909c,
FT                   len: 162 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 162 aa overlap). Probable rpsP, 30S
FT                   ribosomal protein S16, equivalent to O33014|RS16_MYCLE 30S
FT                   RIBOSOMAL PROTEIN S16 from Mycobacterium leprae (160 aa),
FT                   FASTA scores: opt: 828, E(): 1.6e-39, (82.5% identity in
FT                   160 aa overlap). Also highly similar to others e.g.
FT                   O69879|RS16_STRCO 30S RIBOSOMAL PROTEIN S16 from
FT                   Streptomyces coelicolor (139 aa), FASTA scores: opt: 486,
FT                   E(): 1.9e-20, (56.95% identity in 144 aa overlap);
FT                   P80379|RS16_THETH 30S RIBOSOMAL PROTEIN S16 from Thermus
FT                   Thermophilus (88 aa), FASTA scores: opt: 280, E(): 4.8e-09,
FT                   (53.25% identity in 77 aa overlap) (C-terminus shorter);
FT                   P21474|RS16_BACSU|RPSP 30S RIBOSOMAL PROTEIN S16 (BS17)
FT                   from Bacillus subtilis (89 aa,), FASTA scores: opt: 258,
FT                   E(): 8.2e-08, (42.85% identity in 91 aa overlap)
FT                   (C-terminus shorter); etc. BELONGS TO THE S16P FAMILY OF
FT                   RIBOSOMAL PROTEINS."
FT                   /db_xref="GOA:P66436"
FT                   /db_xref="HSSP:1EMW"
FT                   /db_xref="InterPro:IPR000307"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66436"
FT                   /protein_id="CAD96620.1"
FT                   /translation="MAVKIKLTRLGKIRNPQYRVAVADARTRRDGRAIEVIGRYHPKEE
FT                   PSLIEINSERAQYWLSVGAQPTEPVLKLLKITGDWQKFKGLPGAQGRLKVAAPKPSKLE
FT                   VFNAALAAADGGPTTEATKPKKKSPAKKAAKAAEPAPQPEQPDTPALGGEQAELTAES"
FT   CDS             complement(49343..49786)
FT                   /transl_table=11
FT                   /gene="Mb2934c"
FT                   /locus_tag="Mb2934c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2934c, -, len: 147 aa. Equivalent to Rv2910c, len:
FT                   147 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 147 aa overlap). Conserved hypothetical
FT                   protein, showing some similarity with hypothetical proteins
FT                   from other organisms e.g. Q9JN76|MMYY HYPOTHETICAL 17.4 KDA
FT                   PROTEIN from Streptomyces coelicolor (153 aa), FASTA
FT                   scores: opt: 164, E(): 0.00026, (35.05% identity in 129 aa
FT                   overlap); etc. Also some similarity with protein from
FT                   Mycobacterium tuberculosis e.g. O07237|Rv0310c|MTCY63.15c
FT                   (163 aa), FASTA scores: opt: 165, E(): 0.00023, (26.3%
FT                   identity in 137 aa overlap); P96815|Rv0138|MTCI5.12 (167
FT                   aa), FASTA scores: opt: 132, E(): 0.048, (30.25% identity
FT                   in 109 aa overlap); etc."
FT                   /db_xref="UniProtKB/Swiss-Prot:P65054"
FT                   /protein_id="CAD96621.1"
FT                   /translation="MCAVLDRSMLSVAEISDRLEIQQLLVDYSSAIDQRRFDDLDRVFT
FT                   PDAYIDYRALGGIDGRYPKIKQWLSQVLGNFPVYAHMLGNFSVRVDGDTASSRVICFNP
FT                   MVFAGDRQQVLFCGLWYDDDFVRTPDGWRIIRRVETKCFQKMM"
FT   CDS             49855..50730
FT                   /transl_table=11
FT                   /gene="dacB2"
FT                   /locus_tag="Mb2935"
FT                   /product="PROBABLE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE
FT                   DACB2 (PENICILLIN-BINDING PROTEIN) (DD-PEPTIDASE)
FT                   (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE)
FT                   (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE)"
FT                   /EC_number="3.4.16.4"
FT                   /note="Mb2935, dacB2, len: 291 aa. Equivalent to Rv2911,
FT                   len: 291 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 291 aa overlap). Probable dacB2,
FT                   D-alanyl-D-alanine carboxypeptidase (penicillin-binding
FT                   protein) (EC 3.4.16.4), an ala-rich protein. Highly similar
FT                   (except in N-terminus) to Q9CCM2|ML0691 PUTATIVE
FT                   D-ALANYL-D-ALANINE CARBOXYPEPTIDASE from Mycobacterium
FT                   leprae (411 aa), FASTA scores: opt: 749, E(): 9.3e-39,
FT                   (46.75% identity in 276 aa overlap). Also similar to
FT                   penicillin binding proteins / D-alanyl-D-alanine
FT                   carboxypeptidases e.g. Q9KCJ8|SC4G1.16c D-ALANYL-D-ALANINE
FT                   CARBOXYPEPTIDASE from Streptomyces coelicolor (382 aa),
FT                   FASTA scores: opt: 386, E(): 2.1e-16, (31.25% identity in
FT                   285 aa overlap); P35150|DACB_BACSU PENICILLIN-BINDING
FT                   PROTEIN 5* PRECURSOR from Bacillus subtilis (382 aa), FASTA
FT                   scores: opt: 384, E(): 3.6e-17, (30.7% identity in 244 aa
FT                   overlap); Q9K8X5|DACB|BH2877 D-ALANYL-D-ALANINE
FT                   CARBOXYPEPTIDASE (PENICILLIN-BINDING PROTEIN 5) from
FT                   Bacillus halodurans (395 aa), FASTA scores: opt: 359, E():
FT                   9.7e-15, (30.3% identity in 241 aa overlap);
FT                   P33364|PBP7_ECOLI|PBPG|B2134 penicillin-binding protein 7
FT                   precursor from Escherichia coli strain K12 (313 aa), FASTA
FT                   scores: opt: 273, E(): 7.5e-10, (27.8% identity in 263 aa
FT                   overlap); etc. Also similar to O53380|Rv3330|MTV016.30
FT                   PENICILLIN-BINDING PROTEIN from Mycobacterium tuberculosis
FT                   (405 aa), FASTA scores: opt: 746, E(): 1.4e-38, (47.0%
FT                   identity in 266 aa overlap). Seems to contain PF00768
FT                   Peptidase_S11 domain PFAM. BELONGS TO PEPTIDASE FAMILY S11;
FT                   ALSO KNOWN AS THE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE 1
FT                   FAMILY. Thought to be a membrane-bound protein. Note that
FT                   previously known as dacB."
FT                   /db_xref="GOA:Q7TXM5"
FT                   /db_xref="HSSP:1J9M"
FT                   /db_xref="InterPro:IPR018044"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM5"
FT                   /protein_id="CAD96622.1"
FT                   /translation="MRKLMTATAALCACAVTVSAGAAWADADVQPAGSVPIPDGPAQTW
FT                   IVADLDSGQVLAGRDQNVAHPPASTIKVLLALVALDELDLNSTVVADVADTQAECNCVG
FT                   VKPGRSYTARQLLDGLLLVSGNDAANTLAHMLGGQDVTVAKMNAKAATLGATSTHATTP
FT                   SGLDGPGGSGASTAHDLVVIFRAAMANPVFAQITAEPSAMFPSDNGEQLIVNQDELLQR
FT                   YPGAIGGKTGYTNAARKTFVGAAARGGRRLVIAMMYGLVKEGGPTYWDQAATLFDWGFA
FT                   LNPQASVGSL"
FT   CDS             complement(50790..51377)
FT                   /transl_table=11
FT                   /gene="Mb2936c"
FT                   /locus_tag="Mb2936c"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
FT                   (PROBABLY TETR-FAMILY)"
FT                   /note="Mb2936c, -, len: 195 aa. Equivalent to Rv2912c, len:
FT                   195 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 195 aa overlap). Probable transcription
FT                   regulatory protein, tetR family, showing similarity with
FT                   others e.g. Q9K3V9|SCD10.17 PUTATIVE TETR-FAMILY
FT                   TRANSCRIPTIONAL from Streptomyces coelicolor (202 aa),
FT                   FASTA scores: opt: 185, E(): 4.4e-05, (31.15% identity in
FT                   167 aa overlap); Q9KFQ0 TETR-FAMILY from Bacillus
FT                   halodurans (185 aa), FASTA scores: opt: 164, E(): 0.001,
FT                   (35.6% identity in 73 aa overlap);
FT                   P17446|BETI_ECOLI|BETI|B0313 regulatory protein from
FT                   Escherichia coli strain K12 (195 aa), FASTA scores: opt:
FT                   126, E(): 0.024, (24.5% identity in 196 aa overlap); etc.
FT                   Contains possible helix-turn-helix motif at aa 33-54 (+2.71
FT                   SD). POSSIBLY BELONGS TO THE TETR/ACRR FAMILY."
FT                   /db_xref="GOA:P67441"
FT                   /db_xref="InterPro:IPR001647"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67441"
FT                   /protein_id="CAD96623.1"
FT                   /translation="MARTQQQRREETVARLLQASIDTIIEVGYARASAAVITKRAGVSV
FT                   GALFRHFETMGDFMAATAYEVLRRQLETFTKQVAEIPADRPALPAALTILRDITAGSTN
FT                   AVLYELMVAARTDEKLKETLQNVLGQYSAKIHDAARALPGAESFPEETFPVIVALMTNV
FT                   FDGAAIVRGVLPQPELEEQRIPMLTALLTAGL"
FT   CDS             complement(51379..53214)
FT                   /transl_table=11
FT                   /gene="Mb2937c"
FT                   /locus_tag="Mb2937c"
FT                   /product="POSSIBLE D-AMINO ACID AMINOHYDROLASE"
FT                   /EC_number="3.5.1.-"
FT                   /note="Mb2937c, -, len: 611 aa. Equivalent to Rv2913c, len:
FT                   611 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 611 aa overlap). Possible D-amino acid
FT                   aminohydrolase (EC 3.5.1.-), similar (principally in
FT                   N-terminus) to D-amino acid aminohydrolases e.g.
FT                   Q9V2D3|NDAD|PAB0090 D-AMINOACYLASE (ASPARTATE, GLUTAMATE
FT                   ETC) from Pyrococcus abyssi (526 aa), FASTA scores: opt:
FT                   336, E(): 2.2e-13, (27.55% identity in 581 aa overlap);
FT                   P94212|NDDD_ALCXX N-ACYL-D-ASPARTATE DEACYLASE (EC
FT                   3.5.1.83) (N-ACYL-D-ASPARTATE AMIDOHYDROLASE) from
FT                   Alcaligenes xylosoxydans xylosoxydans (Achromobacter
FT                   xylosoxidans) (498 aa), FASTA scores: opt: 221, E():
FT                   3.4e-06, (25.95% identity in 532 aa overlap); Q9AGH8
FT                   D-AMINOACYLASE (EC 3.5.1.81) from Alcaligenes faecalis (484
FT                   aa), FASTA scores: opt: 218, E(): 5.1e-06, (28.35% identity
FT                   in 434 aa overlap); etc."
FT                   /db_xref="GOA:P65531"
FT                   /db_xref="InterPro:IPR006680"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65531"
FT                   /protein_id="CAD96624.1"
FT                   /translation="MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVV
FT                   ATVAAGALDETGCPEVVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLG
FT                   NCSLSTVYANSEDAADLFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVS
FT                   SLLGHSDLRTAVLGLDRATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLD
FT                   GDRFRSRALPSTFATWRERRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRR
FT                   KGVRMSMLVSADAKSMPLAVHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVF
FT                   EEFGAGTAALHLRDQLQRNELLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPD
FT                   KSLIGKSFGAIADERGLHPLDAFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVH
FT                   MGFSDAGAHLRNMAFYNFGLRLLKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAG
FT                   TLRQGDRADFAVIDPTHLDESVDGYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFR
FT                   GGQFGGQFRDGYGQNVKSGRYLRAGELGAALSRSA"
FT   CDS             complement(53283..55040)
FT                   /transl_table=11
FT                   /gene="pknI"
FT                   /locus_tag="Mb2938c"
FT                   /product="PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN
FT                   KINASE I PKNI (PROTEIN KINASE I) (STPK I) (PHOSPHORYLASE B
FT                   KINASE KINASE) (HYDROXYALKYL-PROTEIN KINASE)"
FT                   /EC_number="2.7.1.37"
FT                   /note="Mb2938c, pknI, len: 585 aa. Equivalent to Rv2914c,
FT                   len: 585 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 585 aa overlap). Probable pknI,
FT                   transmembrane serine/threonine-protein kinase (EC 2.7.1.-)
FT                   (see citation below), ala-rich protein, highly similar to
FT                   many in Mycobacterium tuberculosis and other bacteria e.g.
FT                   Q9RLQ7|MBK PUTATIVE SERINE/THREONINE PROTEIN KINASE from
FT                   Mycobacterium bovis BCG (291 aa), FASTA scores: opt: 376,
FT                   E(): 1.1e-10, (36.95% identity in 287 aa overlap);
FT                   P33973|PKN1_MYXXA serine/threonine-protein kinase from
FT                   Myxococcus xanthus (693 aa), FASTA scores: opt: 286, E():
FT                   5.4e-10, (29.9% identity in 374 aa overlap);
FT                   P72003|PKNF_MYCTU|Rv1746|MT1788|MTCY28.09 PROBABLE
FT                   SERINE/THREONINE-PROTEIN KINASE from Mycobacterium
FT                   tuberculosis (476 aa), FASTA scores: opt: 675, E():
FT                   1.7e-24, (39.75% identity in 468 aa overlap);
FT                   Q10697|PKNJ_MYCTU|Rv2088|MT2149|MTCY49.28 PROBABLE
FT                   SERINE/THREONINE-PROTEIN KINASE from Mycobacterium
FT                   tuberculosis (589 aa), FASTA scores: opt: 574, E(): 1e-19,
FT                   (34.85% identity in 479 aa overlap); etc. Equivalent to
FT                   AAK47308 from Mycobacterium tuberculosis strain CDC1551
FT                   (603 aa) but shorter 18 aa. Contains Hank's kinase
FT                   subdomain. BELONGS TO THE SER/THR FAMILY OF PROTEIN
FT                   KINASES."
FT                   /db_xref="GOA:P65731"
FT                   /db_xref="HSSP:1O6Y"
FT                   /db_xref="InterPro:IPR008271"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65731"
FT                   /protein_id="CAD96625.1"
FT                   /translation="MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSP
FT                   AMAADDEFRRRFQRETEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADR
FT                   FPAVLPVGEVLAIVTAVAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA
FT                   SQPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDL
FT                   ARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAY
FT                   VVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPA
FT                   SPTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTV
FT                   AVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDN
FT                   DHTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDL
FT                   VGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPP
FT                   TTTAPGPGR"
FT   CDS             complement(55084..56196)
FT                   /transl_table=11
FT                   /gene="Mb2939c"
FT                   /locus_tag="Mb2939c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2939c, -, len: 370 aa. Equivalent to Rv2915c, len:
FT                   370 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 370 aa overlap). Conserved hypothetical
FT                   protein, posssibly XAA-PRO dipeptidase (prolidase) (EC
FT                   3.4.13.9), highly similar to CAC38796|SCI39.08c CONSERVED
FT                   HYPOTHETICAL PROTEIN from Streptomyces coelicolor (363 aa),
FT                   FASTA scores: opt: 1341, E(): 5.5e-76, (56.65% identity in
FT                   362 aa overlap); and similar to prolidases (XAA-PRO
FT                   dipeptidase) e.g. Q9ABC9|CC0300 PUTATIVE XAA-PRO
FT                   DIPEPTIDASE from Caulobacter crescentus (428 aa), FASTA
FT                   scores: opt: 327, E(): 7.4e-13, (30.2% identity in 374 aa
FT                   overlap); Q97XD4 PROLIDASE from Sulfolobus solfataricus
FT                   (396 aa), FASTA scores: opt: 271, E(): 2.1e-09, (30.5%
FT                   identity in 354 aa overlap); Q9WX55 PROLIDASE from
FT                   Microbacterium esteraromaticum (393 aa), FASTA scores: opt:
FT                   256, E(): 1.8e-08, (27.95% identity in 365 aa overlap);
FT                   etc. Also similar to O53619|Rv0074|MTV030.18 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (411
FT                   aa), FASTA scores: opt: 243, E(): 1.2e-07, (27.5% identity
FT                   in 389 aa overlap)."
FT                   /db_xref="GOA:P68916"
FT                   /db_xref="InterPro:IPR006680"
FT                   /db_xref="UniProtKB/Swiss-Prot:P68916"
FT                   /protein_id="CAD96626.1"
FT                   /translation="MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAG
FT                   ADTVFDGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRDCGSPTDTR
FT                   GLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAVAEQARRGDGWVKLVGDW
FT                   IDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTAHVFSEDALPGLINAGIDCIEHGTGLT
FT                   DDTIALMLEHGTALVPTLINLENFPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAG
FT                   VPVYAGTDAGSTIEHGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASAD
FT                   LLCYAQDPRQGPGVLQHPDLVILRGRTFGP"
FT   CDS             complement(56224..57801)
FT                   /transl_table=11
FT                   /gene="ffh"
FT                   /locus_tag="Mb2940c"
FT                   /product="PROBABLE SIGNAL RECOGNITION PARTICLE PROTEIN FFH
FT                   (FIFTY-FOUR HOMOLOG)"
FT                   /note="Mb2940c, ffh, len: 525 aa. Equivalent to Rv2916c,
FT                   len: 525 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 525 aa overlap). Probable ffh, signal
FT                   recognition particle protein (ala-, gly-, leu-rich
FT                   protein), equivalent to O33013|SR54_MYCLE SIGNAL
FT                   RECOGNITION PARTICLE from Mycobacterium leprae (521 aa),
FT                   FASTA scores: opt: 2968, E(): 1.6e-145, (87.85% identity in
FT                   526 aa overlap). Also highly similar to others e.g.
FT                   O69874|FFH from Streptomyces coelicolor (550 aa), FASTA
FT                   scores: opt: 2025, E(): 6e-97, (63.8% identity in 519 aa
FT                   overlap) (N-terminus longer 34 aa); P37105|SR54_BACSU from
FT                   Bacillus subtilis (446 aa), FASTA scores: opt: 1451, E():
FT                   1.9e-67, (51.5% identity in 435 aa overlap); BAB57399|FFH
FT                   from Staphylococcus aureus subsp. aureus Mu50 (455 aa),
FT                   FASTA scores: opt: 1418, E(): 9.4e-66, (48.65% identity in
FT                   448 aa overlap); etc. Contains PS00017 ATP/GTP-binding site
FT                   motif A (P-loop). BELONGS TO THE SRP FAMILY OF GTP-BINDING
FT                   PROTEINS. NOTE THAT SIGNAL RECOGNITION PARTICLE CONSISTS OF
FT                   A SMALL CYTOPLASMIC RNA (SC-RNA) MOLECULE AND PROTEIN FFH.
FT                   THE PROTEIN HAS A TWO DOMAIN STRUCTURE: THE G-DOMAIN BINDS
FT                   GTP; THE M-DOMAIN BINDS THE RNA AND ALSO BINDS THE SIGNAL
FT                   SEQUENCE."
FT                   /db_xref="GOA:P66845"
FT                   /db_xref="HSSP:2FFH"
FT                   /db_xref="InterPro:IPR004125"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66845"
FT                   /protein_id="CAD96627.1"
FT                   /translation="MFESLSDRLTAALQGLRGKGRLTDADIDATTREIRLALLEADVSL
FT                   PVVRAFIHRIKERARGAEVSSALNPAQQVVKIVNEELISILGGETRELAFAKTPPTVVM
FT                   LAGLQGSGKTTLAGKLAARLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHP
FT                   GASPESGPGDPVAVAAAGLAEARAKHFDVVIVDTAGRLGIDEELMAQAAAIRDAINPDE
FT                   VLFVLDAMIGQDAVTTAAAFGEGVGFTGVALTKLDGDARGGAALSVREVTGVPILFAST
FT                   GEKLEDFDVFHPDRMASRILGMGDVLSLIEQAEQVFDAQQAEEAAAKIGAGELTLEDFL
FT                   EQMLAVRKMGPIGNLLGMLPGAAQMKDALAEVDDKQLDRVQAIIRGMTPQERADPKIIN
FT                   ASRRLRIANGSGVTVSEVNQLVERFFEARKMMSSMLGGMGIPGIGRKSATRKSKGAKGK
FT                   SGKKSKKGTRGPTPPKVKSPFGVPGMPGLAGLPGGLPDLSQMPKGLDELPPGLADFDLS
FT                   KLKFPGKK"
FT   CDS             57879..59759
FT                   /transl_table=11
FT                   /gene="Mb2941"
FT                   /locus_tag="Mb2941"
FT                   /product="CONSERVED HYPOTHETICAL ALANINE AND ARGININE RICH
FT                   PROTEIN"
FT                   /note="Mb2941, -, len: 626 aa. Equivalent to Rv2917, len:
FT                   626 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 626 aa overlap). Conserved hypothetical
FT                   ala-, arg-rich protein, highly similar (but longer 34 aa)
FT                   to O33011|ML1624|MLCB250.18C HYPOTHETICAL 65.2 KDA PROTEIN
FT                   from Mycobacterium leprae (596 aa), FASTA scores: opt:
FT                   3117, E(): 9e-183, (79.8% identity in 584 aa overlap). Also
FT                   highly similar to Q9S2E8|SCE19A.36C HYPOTHETICAL 66.2 KDA
FT                   PROTEIN from Streptomyces coelicolor (598 aa), FASTA
FT                   scores: opt: 1921, E(): 1.1e-109, (56.08% identity in 567
FT                   aa overlap); and Q9S3Y6|SDRA SDRA PROTEIN from Streptomyces
FT                   coelicolor (597 aa), FASTA scores: opt: 1896, E():
FT                   3.6e-108, (55.75% identity in 567 aa overlap). And shows
FT                   some similarity with others proteins from other organisms.
FT                   Equivalent to AAK47311 putative RNA helicase from
FT                   Mycobacterium tuberculosis strain CDC1551 (602 aa) but
FT                   longer 24 aa. Contains PS00017 ATP/GTP-binding site motif
FT                   (P-loop)."
FT                   /db_xref="GOA:Q7TXM4"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM4"
FT                   /protein_id="CAD96628.1"
FT                   /translation="MRVTRLVDAESTRCDVGPAPKSVAMLHFTAATSRFRLGRERANSV
FT                   RSDGGWGVLQPVSATFNPPLRGWQRRALVQYLGTQPRDFLAVATPGSGKTSFALRIAAE
FT                   LLRYHTVEQVTVVVPTEHLKVQWAHAAAAHGLSLDPKFANSNPQTSPEYHGVMVTYAQV
FT                   ASHPTLHRVRTEARKTLVVFDEIHHGGDAKTWGDAIREAFGDATRRLALTGTPFRSDDS
FT                   PIPFVSYQPDADGVLRSQADHTYGYAEALADGVVRPVVFLAYSGQARWRDSAGEEYEAR
FT                   LGEPLSAEQTARAWRTALDPEGEWMPAVITAADRRLRQLRAHVPDAGGMIIASDRTTAR
FT                   AYARLLTTMTAEEPTVVLSDDPGSSARITEFAQGTSRWLVAVRMVSEGVDVPRLSVGVY
FT                   ATNASTPLFFAQAIGRFVRSRRPGETASIFVPSVPNLLQLASALEVQRNHVLGRPHRES
FT                   AHDPLDGDPATRTQTERGGAERGFTALGADAELDQVIFDGSSFGTATPTGSDEEADYLG
FT                   IPGLLDAEQMRALLHRRQDEQLRKRAQLQKGATQPATSGASASVHGQLRDLRRELHTLV
FT                   SIAHHRTGKPHGWIHDELRRRCGGPPIAAATRAQIKARIDALRQLNSERS"
FT   CDS             complement(59770..62196)
FT                   /transl_table=11
FT                   /gene="glnD"
FT                   /locus_tag="Mb2942c"
FT                   /product="PROBABLE [PROTEIN-PII] URIDYLYLTRANSFERASE GLND
FT                   (PII URIDYLYL-TRANSFERASE) (URIDYLYL REMOVING ENZYME)
FT                   (UTASE)"
FT                   /EC_number="2.7.7.59"
FT                   /note="Mb2942c, glnD, len: 808 aa. Equivalent to Rv2918c,
FT                   len: 808 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 808 aa overlap). Probable glnD,
FT                   uridylyltransferase (ala-rich protein) (EC 2.7.7.59),
FT                   similar to other uridylyltransferases e.g. O69873||SC2E1.02
FT                   from Streptomyces coelicolor (835 aa), FASTA scores: opt:
FT                   1473, E(): 2.8e-81, (41.03% identity in 858 aa overlap);
FT                   P43919|GLND_HAEIN from Haemophilus influenzae (863 aa),
FT                   FASTA scores: opt: 333, E(): 2.5e-12, (25.4% identity in
FT                   819 aa overlap); P27249|GLND_ECOLI|GLND|B0167 from
FT                   Escherichia coli strain K12 (890 aa), FASTA scores: opt:
FT                   306, E(): 1.1e-10, (27.75% identity in 858 aa overlap);
FT                   etc. BELONGS TO THE GLND FAMILY."
FT                   /db_xref="GOA:Q7TXM3"
FT                   /db_xref="InterPro:IPR013546"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM3"
FT                   /protein_id="CAD96629.1"
FT                   /translation="MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLI
FT                   DKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLLHDGKPADILRPVADRLWYPLW
FT                   DANIRLDHSVRTVSEALTIANSDLMAALGMLEARHIAGDQQLSFALIDGVRRQWRNGIR
FT                   SRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTD
FT                   RPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAG
FT                   RTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPG
FT                   LVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEA
FT                   LDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGA
FT                   LLHDIGKGRGTDHSVLGAELVIPVCTRLGLSPPDVWTLSKLVRHHLLLPITATRRDLND
FT                   PKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGE
FT                   SLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLALNSLR
FT                   VHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAAS
FT                   LVSARAGDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAG
FT                   AGIVWAKVNTFGSTAADVFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD"
FT   CDS             complement(62254..62592)
FT                   /transl_table=11
FT                   /gene="glnB"
FT                   /locus_tag="Mb2943c"
FT                   /product="PROBABLE NITROGEN REGULATORY PROTEIN P-II GLNB"
FT                   /note="Mb2943c, glnB, len: 112 aa. Equivalent to Rv2919c,
FT                   len: 112 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 112 aa overlap). Probable glnB,
FT                   nitrogen regulatory protein, highly similar to others e.g.
FT                   Q9X705|GLNB PII PROTEIN from Corynebacterium glutamicum
FT                   (Brevibacterium flavum) (112 aa), FASTA scores: opt: 531,
FT                   E(): 4.5e-30, (68.75% identity in 112 aa overlap);
FT                   P21193|GLNB_AZOBR NITROGEN REGULATORY PROTEIN P-II from
FT                   Azospirillum brasilense (112 aa), FASTA scores: opt: 496,
FT                   E(): 1.2e-27, (60.7% identity in 112 aa overlap);
FT                   P05826|GLNB_ECOLI|B2553|Z3829|ECS3419|STY2808 NITROGEN
FT                   REGULATORY PROTEIN P-II from Escherichia coli strains K12
FT                   and O157:H7 (112 aa), FASTA scores: opt: 487, E(): 5.3e-27,
FT                   (61.6% identity in 112 aa overlap); etc. Contains PS00496
FT                   P-II protein urydylation site. BELONGS TO THE P(II) PROTEIN
FT                   FAMILY."
FT                   /db_xref="GOA:P64250"
FT                   /db_xref="HSSP:2PII"
FT                   /db_xref="InterPro:IPR002332"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64250"
FT                   /protein_id="CAD96630.1"
FT                   /translation="MKLITAIVKPFTLDDVKTSLEDAGVLGMTVSEIQGYGRQKGHTEV
FT                   YRGAEYSVDFVPKVRIEVVVDDSIVDKVVDSIVRAARTGKIGDGKVWVSPVDTIVRVRT
FT                   GERGHDAL"
FT   CDS             complement(62589..64022)
FT                   /transl_table=11
FT                   /gene="amt"
FT                   /locus_tag="Mb2944c"
FT                   /product="PROBABLE AMMONIUM-TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN AMT"
FT                   /note="Mb2944c, amt, len: 477 aa. Equivalent to Rv2920c,
FT                   len: 477 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 477 aa overlap). Probable amt,
FT                   ammonium-transport integral membrane protein (ala-, gly-,
FT                   leu-, val-rich protein), highly similar to others e.g.
FT                   Q9ZBP6|SC7A1.27 AMMONIUM TRANSPORTER from Streptomyces
FT                   coelicolor (448 aa), FASTA scores: opt: 1246, E(): 7.3e-67,
FT                   (54.1% identity in 462 aa overlap); P54146|AMT_CORGL
FT                   AMMONIUM TRANSPORT SYSTEM from Corynebacterium glutamicum
FT                   (452 aa), FASTA scores: opt: 953, E(): 2.1e-49, (41.45%
FT                   identity in 475 aa overlap); Q07429|NRGA_BACSU PROBABLE
FT                   AMMONIUM TRANSPORTER (MEMBRANE PROTEIN NRGA) from Bacillus
FT                   subtilis (404 aa), FASTA scores: opt: 721, E(): 0, (44.4%
FT                   identity in 430 aa overlap); etc. BELONGS TO THE
FT                   AMT1/MEP/NRGA FAMILY OF AMMONIUM TRANSPORTERS (TC 2.49)."
FT                   /db_xref="GOA:P63520"
FT                   /db_xref="InterPro:IPR018047"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63520"
FT                   /protein_id="CAD96631.1"
FT                   /translation="MDQFPIMGVPDGGDTAWMLVSSALVLLMTPGLAFFYGGMVRSKSV
FT                   LNMIMMSISAMGVVTVLWALYGYSIAFGDDVGNIAGNPSQYWGLKGLIGVNAVAADPST
FT                   QTAAVNIPLAGTLPATVFVAFQLMFAIITVALISGAVADRLKFGAWLLFAGLWATFVYF
FT                   PVAHWVFAFDGFAAEHGGWIANKLHAIDFAGGTAVHINAGVAALMLAIVLGKRRGWPAT
FT                   LFRPHNLPFVMLGAALLWFGWYGFNAGSATTANGVAGATFVTTTIATAAAMLGWLLTER
FT                   VRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALAVGVSAGVLCALAVGLKFKLGFDD
FT                   SLDVVGVHLVGGLVGTLLVGLLAAPEAPAINGVAGVSKGLFYGGGFAQLERQALGACSV
FT                   LVYSGIITLILALILKFTIGLRLDAEQESTGIDEAEHAESGYDFAVASGSVLPPRVTVE
FT                   DSRNGIQERIGQKVEAEPK"
FT   CDS             complement(64499..65767)
FT                   /transl_table=11
FT                   /gene="ftsY"
FT                   /locus_tag="Mb2945c"
FT                   /product="PROBABLE CELL DIVISION PROTEIN FTSY"
FT                   /note="Mb2945c, ftsY, len: 422 aa. Equivalent to Rv2921c,
FT                   len: 422 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 422 aa overlap). Probable ftsY,
FT                   membrane-associated cell division protein, equivalent to
FT                   O33010|FTSY_MYCLE CELL DIVISION PROTEIN FTSY HOMOLOG from
FT                   Mycobacterium leprae (430 aa), FASTA scores: opt: 1760,
FT                   E(): 1.1e-108, (81.35% identity in 429 aa overlap). Also
FT                   similar to others e.g. Q9I6C1|FTSY|PA0373 SIGNAL
FT                   RECOGNITION PARTICLE RECEPTOR FTSY from Pseudomonas
FT                   aeruginosa (455 aa), FASTA scores: opt: 882, E(): 5.1e-40,
FT                   (42.08% identity in 385 aa overlap); Q9KVJ6|FTSY CELL
FT                   DIVISION PROTEIN from Vibrio cholerae (391 aa), FASTA
FT                   scores: opt: 837, E(): 1.2e-37, (36.3% identity in 394 aa
FT                   overlap); P10121|FTSY_ECOLI|FTSY|B3464 CELL DIVISION
FT                   PROTEIN from Escherichia coli strain K12 (497 aa), FASTA
FT                   scores: opt: 800, E(): 1.3e-35, (39.75% identity in 327 aa
FT                   overlap); etc. Also similar to Q9ZBP9|SC7A1.24 PUTATIVE
FT                   PROKARYOTIC DOCKING PROTEIN from Streptomyces coelicolor
FT                   (412 aa), FASTA scores: opt: 1461, E(): 4.3e-71, (60.3%
FT                   identity in 423 aa overlap). Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop), and PS00300
FT                   SRP54-type proteins GTP-binding domain signature. BELONGS
FT                   TO THE SRP FAMILY OF GTP-BINDING PROTEINS."
FT                   /db_xref="GOA:P66843"
FT                   /db_xref="HSSP:1FTS"
FT                   /db_xref="InterPro:IPR013822"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66843"
FT                   /protein_id="CAD96632.1"
FT                   /translation="MWEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVD
FT                   RSGGYTASSGITFSQTPTTQPAERIDTSGLPAVGDDATVPRDAPKRTIADVHLPEFEPE
FT                   PQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDVEDTLL
FT                   VADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMDRSIRALPHAGH
FT                   PSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAV
FT                   VRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASV
FT                   DEVLLVLDATIGQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLV
FT                   GLGEGPDDLAPFEPAAFVDALLG"
FT   CDS             complement(65817..69434)
FT                   /transl_table=11
FT                   /gene="smc"
FT                   /locus_tag="Mb2946c"
FT                   /product="PROBABLE CHROMOSOME PARTITION PROTEIN SMC"
FT                   /note="Mb2946c, smc, len: 1205 aa. Equivalent to Rv2922c,
FT                   len: 1205 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 1205 aa overlap). Probable smc,
FT                   chromosome partition protein (ala-, arg-, leu-, glu-rich
FT                   protein, possibly coiled-coil protein) (see * below),
FT                   equivalent (but longer 84 aa) to
FT                   Q9CBT5|SMC|ML1629|MLCB250.01 POSSIBLE CELL DIVISION PROTEIN
FT                   from Mycobacterium leprae (1203 aa), FASTA scores: opt:
FT                   5957, E(): 0, (79.15% identity in 1205 aa overlap). Also
FT                   highly similar to other chromosome segregation proteins
FT                   e.g. Q9ZBQ2|SC7A1.21 PUTATIVE CHROMOSOME ASSOCIATED PROTEIN
FT                   from Streptomyces coelicolor (1186 aa), FASTA scores: opt:
FT                   2633, E(): 4.1e-120, (53.03% identity in 1205 aa overlap);
FT                   P51834|SMC_BACSU CHROMOSOME PARTITION PROTEIN from Bacillus
FT                   subtilis (1186 aa), FASTA scores: opt: 1009, E(): 2.1e-41,
FT                   (30.75% identity in 1205 aa overlap); Q9CHC9|SMC CHROMOSOME
FT                   SEGREGATION PROTEIN from Lactococcus lactis (subsp. lactis)
FT                   (Streptococcus lactis) (924 aa), FASTA scores: opt: 996,
FT                   E(): 7.5e-41, (29.75% identity in 874 aa overlap); etc.
FT                   Equivalent to AAK47317 from Mycobacterium tuberculosis
FT                   strain CDC1551 (1205 aa) but longer 84 aa. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop). BELONGS TO THE SMC
FT                   FAMILY. N-terminus shortened since first submission.
FT                   [*Note: Cobbe N., Heck M.M.S.- Phylogenetic analysis of SMC
FT                   proteins (OCT-2001)]."
FT                   /db_xref="GOA:Q7TXM2"
FT                   /db_xref="HSSP:1E69"
FT                   /db_xref="InterPro:IPR011890"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM2"
FT                   /protein_id="CAD96633.1"
FT                   /translation="MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVDALA
FT                   WVMGEQGAKTLRGGKMEDVIFAGTSSRAPLGRAEVTVSIDNSDNALPIEYTEVSITRRM
FT                   FRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLEEILQSRPEDRRAFIEE
FT                   AAGVLKHRKRKEKALRKLDTMAANLARLTDLTTELRRQLKPLGRQAEAAQRAAAIQADL
FT                   RDARLRLAADDLVSRRAEREAVFQAEAAMRREHDEAAARLAVASEELAAHESAVAELST
FT                   RAESIQHTWFGLSALAERVDATVRIASERAHHLDIEPVAVSDTDPRKPEELEAEAQQVA
FT                   VAEQQLLAELDAARARLDAARAERADRERRAAEADRAHLAAVREEADRREGLARLAGQV
FT                   ETMRARVESIDESVARLSERIEDAAMRAQQTRAEFETVQGRIGELDQGEVGLDEHHERT
FT                   VAALRLADERVAELQSAERAAERQVASLRARIDALAVGLQRKDGAAWLAHNRSGAGLFG
FT                   SIAQLVKVRSGYEAALAAALGPAADALAVDGLTAAGSAVSALKQADGGRAVLVLSDWPA
FT                   PQAPQSASGEMLPSGAQWALDLVESPPQLVGAMIAMLSGVAVVNDLTEAMGLVEIRPEL
FT                   RAVTVDGDLVGAGWVSGGSDRKLSTLEVTSEIDKARSELAAAEALAAQLNAALAGALTE
FT                   QSAGQDAAEQALAALNESDTAISAMYEQLGRLGQEARAAEEEWNRLLQQRTEQEAVRTQ
FT                   TLDDVIQLETQLRKAQETQRVQVAQPIDRQAISAAADRARGVEVEARLAVRTAEERANA
FT                   VRGRADSLRRAAAAEREARVRAQQARAARLHAAAVAAAVADCGRLLAGRLHRAVDGASQ
FT                   LRDASAAQRQQRLAAMAAVRDEVNTLSARVGELTDSLHRDELANAQAALRIEQLEQMVL
FT                   EQFGMAPADLITEYGPHVALPPTELEMAEFEQARERGEQVIAPAPMPFDRVTQERRAKR
FT                   AERALAELGRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLGVVADVDARILQVFN
FT                   DAFVDVEREFRGVFTALFPGGEGRLRLTEPDDMLTTGIEVEARPPGKKITRLSLLSGGE
FT                   KALTAVAMLVAIFRARPSPFYIMDEVEAALDDVNLRRLLSLFEQLREQSQIIIITHQKP
FT                   TMEVADALYGVTMQNDGITAVISQRMRGQQVDQLVTNSS"
FT   CDS             complement(69446..69727)
FT                   /transl_table=11
FT                   /gene="acyP"
FT                   /locus_tag="Mb2947c"
FT                   /product="PROBABLE ACYLPHOSPHATASE ACYP (ACYLPHOSPHATE
FT                   PHOSPHOHYDROLASE)"
FT                   /EC_number="3.6.1.7"
FT                   /note="Mb2947c, acyP, len: 93 aa. Equivalent to Rv2922A,
FT                   len: 93 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 93 aa overlap). Probable acyP,
FT                   acylphosphatase (acylphosphate phosphohydrolase) (EC
FT                   3.6.1.7), highly similar to others e.g. Q9ZBQ3|SC7A1.20
FT                   PUTATIVE ACYLPHOSPHATASE from Streptomyces coelicolor (93
FT                   aa), FASTA scores: opt: 345, E(): 9.5e-19, (58.9% identity
FT                   in 90 aa overlap);
FT                   P75877|ACYP_ECOLI|YCCX|B0968|Z1320|ECS1052 PUTATIVE
FT                   ACYLPHOSPHATASE from Escherichia coli strains K12 and
FT                   O157:H7 (92 aa), FASTA scores: opt: 220, E(): 2e-09,
FT                   (44.95% identity in 89 aa overlap); Q9RVU3|DR0929 PUTATIVE
FT                   ACYLPHOSPHATASE from Deinococcus radiodurans (87 aa), FASTA
FT                   scores: opt: 193, E(): 2.1e-07, (44.3% identity in 79 aa
FT                   overlap); etc. BELONGS TO THE ACYLPHOSPHATASE FAMILY."
FT                   /db_xref="GOA:P69418"
FT                   /db_xref="InterPro:IPR017968"
FT                   /db_xref="UniProtKB/Swiss-Prot:P69418"
FT                   /protein_id="CAD96634.1"
FT                   /translation="MSAPDVRLTAWVHGWVQGVGFRWWTRCRALELGLTGYAANHADGR
FT                   VLVVAQGPRAACQKLLQLLQGDTTPGRVAKVVADWSQSTEQITGFSER"
FT   CDS             complement(69714..70127)
FT                   /transl_table=11
FT                   /gene="Mb2948c"
FT                   /locus_tag="Mb2948c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2948c, -, len: 137 aa. Equivalent to Rv2923c, len:
FT                   137 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 137 aa overlap). Conserved hypothetical
FT                   protein, showing similarity with other hypothetical
FT                   proteins e.g. P24246|YHFA_ECOLI|B3356|Z4717|ECS4207 from
FT                   Escherichia coli strains K12 and O157:H7 (134 aa), FASTA
FT                   scores: opt: 110, E(): 1.9, (25.9% identity in 135 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:P65056"
FT                   /db_xref="InterPro:IPR003718"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65056"
FT                   /protein_id="CAD96635.1"
FT                   /translation="MTQLWVERTGTRRYIGRSTRGAQVLVGSEDVDGVFTPGELLKIAL
FT                   AACSGMASDQPLARRLGDDYQAVVKVSGAADRDQERYPLIEETMELDLSGLTEDEKERL
FT                   LVVINRAVELACTVGRTLKSGTTVNLEVVDVGA"
FT   CDS             complement(70229..71098)
FT                   /transl_table=11
FT                   /gene="fpg"
FT                   /locus_tag="Mb2949c"
FT                   /product="PROBABLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE FPG
FT                   (FAPY-DNA GLYCOSYLASE)"
FT                   /EC_number="3.2.2.23"
FT                   /note="Mb2949c, fpg, len: 289 aa. Equivalent to Rv2924c,
FT                   len: 289 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 289 aa overlap). Probable fpg
FT                   (alternate gene name: mutM), formamidopyrimidine-DNA
FT                   glycosylase (EC 3.2.2.23), equivalent to O69470|FPG_MYCLE
FT                   FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE from Mycobacterium
FT                   leprae (282 aa), FASTA scores: opt: 1563, E(): 1.3e-96,
FT                   (80.6% identity in 289 aa overlap). Also highly similar to
FT                   other formamidopyrimidine-DNA glycosylases e.g.
FT                   Q9ZBQ6|FPG_STRCO from Streptomyces coelicolor (286 aa),
FT                   FASTA scores: opt: 1047, E(): 2.9e-62, (57.55% identity in
FT                   292 aa overlap); P95744|FPG_SYNEN from Synechococcus
FT                   elongatus naegeli (284 aa), FASTA scores: opt: 569, E():
FT                   1.9e-30, (37.95% identity in 290 aa overlap);
FT                   P05523|FPG_ECOLI|MUTM|FPG|B3635 from Escherichia coli
FT                   strain K12 (269 aa), FASTA scores: opt: 424, E(): 8.2e-21,
FT                   (33.9% identity in 289 aa overlap); etc. BELONGS TO THE FPG
FT                   FAMILY. COFACTOR: BINDS 1 ZINC ION."
FT                   /db_xref="GOA:P64151"
FT                   /db_xref="HSSP:1K82"
FT                   /db_xref="InterPro:IPR010663"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64151"
FT                   /protein_id="CAD96636.1"
FT                   /translation="MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLT
FT                   ARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRIS
FT                   ALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLR
FT                   RKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMR
FT                   EALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCP
FT                   RCQPRPRK"
FT   CDS             complement(71402..72124)
FT                   /transl_table=11
FT                   /gene="rnc"
FT                   /locus_tag="Mb2950c"
FT                   /product="PROBABLE RIBONUCLEASE III RNC (RNASE III)"
FT                   /EC_number="3.1.26.3"
FT                   /note="Mb2950c, rnc, len: 240 aa. Equivalent to Rv2925c,
FT                   len: 240 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 240 aa overlap). Probable rnc,
FT                   ribonuclease III (RNase III) (EC 3.1.26.3), equivalent to
FT                   O69469|RNC_MYCLE RIBONUCLEASE III from Mycobacterium leprae
FT                   (238 aa). Also highly similar to other ribonucleases III
FT                   e.g. Q9ZBQ7|RNC_STRCO from Streptomyces coelicolor (272
FT                   aa), FASTA scores: opt: 889, E(): 5.4e-51, (62.2% identity
FT                   in 225 aa overlap) (N-terminus longer 21 aa);
FT                   P51833|RNC_BACSU from Bacillus subtilis (249 aa), FASTA
FT                   scores: opt: 493, E(): 5e-25, (43.25% identity in 215 aa
FT                   overlap); P05797|RNC_ECOLI|RNC|B2567|Z3848|ECS3433 from
FT                   Escherichia coli strain O157:H7 and K12 (226 aa), FASTA
FT                   scores: opt: 459, E(): 7.9e-23, (41.8% identity in 213 aa
FT                   overlap); etc. Contains PS00517 Ribonuclease III family
FT                   signature."
FT                   /db_xref="GOA:P66667"
FT                   /db_xref="HSSP:1O0W"
FT                   /db_xref="InterPro:IPR011907"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66667"
FT                   /protein_id="CAD96637.1"
FT                   /translation="MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEF
FT                   LGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGR
FT                   GEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWK
FT                   TSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAA
FT                   AWKALEVLDNAMPGKTSA"
FT   CDS             complement(72121..72744)
FT                   /transl_table=11
FT                   /gene="Mb2951c"
FT                   /locus_tag="Mb2951c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2951c, -, len: 207 aa. Equivalent to Rv2926c, len:
FT                   207 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 207 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O69468|ML1660|MLCB1243.14
FT                   HYPOTHETICAL 23.5 KDA PROTEIN from Mycobacterium leprae
FT                   (217 aa), FASTA scores: opt: 866, E(): 1.4e-48, (67.2%
FT                   identity in 192 aa overlap). Also similar in part to other
FT                   hypothetical proteins e.g. Q9WXZ8 CONSERVED HYPOTHETICAL
FT                   PROTEIN from Thermotoga maritima (182 aa), FASTA scores:
FT                   opt: 254, E(): 3.4e-09, (31.45% identity in 143 aa
FT                   overlap); Q9ZBQ9|SC7A1.14 HYPOTHETICAL 23.5 KDA PROTEIN
FT                   from Streptomyces coelicolor (217 aa), FASTA scores: opt:
FT                   244, E(): 1.7e-08, (45.5% identity in 189 aa overlap);
FT                   O65982 HYPOTHETICAL 26.2 KDA PROTEIN from Clostridium
FT                   thermosaccharolyticum (Thermoanaerobacterium
FT                   thermosaccharolyticum) (228 aa), FASTA scores: opt: 220,
FT                   E(): 6.1e-07, (32.45% identity in 148 aa overlap); etc.
FT                   Equivalent to AAK47323 from Mycobacterium tuberculosis
FT                   strain CDC1551 (195 aa) but longer 12 aa."
FT                   /db_xref="InterPro:IPR003772"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65058"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96638.1"
FT                   /translation="MDLGGVRRRISLMARQHGPTAQRHVASPMTVDIARLGRRPGAMFE
FT                   LHDTVHSPARIGLELIAIDQGALLDLDLRVESVSEGVLVTGTVAAPTVGECARCLSPVR
FT                   GRVQVALTELFAYPDSATDETTEEDEVGRVVDETIDLEQPIIDAVGLELPFSPVCRPDC
FT                   PGLCPQCGVPLASEPGHRHEQIDPRWAKLVEMLGPESDTLRGER"
FT   CDS             complement(72795..73532)
FT                   /transl_table=11
FT                   /gene="Mb2952c"
FT                   /locus_tag="Mb2952c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2952c, -, len: 245 aa. Equivalent to Rv2927c, len:
FT                   245 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 245 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBS6|ML1661|MLCB1243.13 (alias
FT                   O69467) HYPOTHETICAL PROTEIN from Mycobacterium leprae (247
FT                   aa), FASTA scores: opt: 1440, E(): 4.9e-76, (90.6% identity
FT                   in 245 aa overlap). Also similar to many hypothetical
FT                   proteins from other organisms e.g. Q9ZBR0|SC7A1.13
FT                   HYPOTHETICAL 41.0 KDA PROTEIN from Streptomyces coelicolor
FT                   (379 aa), FASTA scores: opt: 266, E(): 3.4e-08, (29.9%
FT                   identity in 234 aa overlap); etc. Also some similarity with
FT                   P46815|AG84_MYCLE|ML0922 ANTIGEN 84 from Mycobacterium
FT                   leprae (266 aa), FASTA scores: opt: 193, E(): 0.00043,
FT                   (28.7% identity in 136 aa overlap) (see citation below);
FT                   and P46816|AG84_MYCTU|WAG31|Rv2145c|MT2204|MTCY270.23
FT                   ANTIGEN 84 from Mycobacterium tuberculosis (260 aa), FASTA
FT                   scores: opt: 178, E(): 0.0031, (34.35% identity in 131 aa
FT                   overlap) (see citation below). Contains potential
FT                   coiled-coil region."
FT                   /db_xref="UniProtKB/Swiss-Prot:P65060"
FT                   /protein_id="CAD96639.1"
FT                   /translation="MYRVFEALDELSAIVEEARGVPMTAGCVVPRGDVLELIDDIKDAI
FT                   PGELDDAQDVLDARDSMLQDAKTHADSMVSSATTEAESILNHARTEADRILSDAKAQAD
FT                   RMVSEARQHSERMVADAREEAIRIATAAKREYEASVSRAQAECDRLIENGNISYEKAVQ
FT                   EGIKEQQRLVSQNEVVAAANAESTRLVDTAHAEADRLRGECDIYVDNKLAEFEEFLNGT
FT                   LRSVGRGRHQLRTAAGTHDYAVR"
FT   CDS             73771..74556
FT                   /transl_table=11
FT                   /gene="tesA"
FT                   /locus_tag="Mb2953"
FT                   /product="PROBABLE THIOESTERASE TESA"
FT                   /EC_number="3.1.2.-"
FT                   /note="Mb2953, tesA, len: 261 aa. Equivalent to Rv2928,
FT                   len: 261 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 261 aa overlap). Probable tesA,
FT                   thioesterase (EC 3.1.2.-), equivalent to
FT                   Q9Z5K4|ML2359|MLCB12.04c PUTATIVE THIOESTERASE from
FT                   Mycobacterium leprae (261 aa), FASTA scores: opt: 1326,
FT                   E(): 3.7e-80, (73.2% identity in 261 aa overlap). Also
FT                   similar to others e.g. Q9ZGI1 THIOESTERASE II PIKAV from
FT                   Streptomyces venezuelae (281 aa), FASTA scores: opt: 535,
FT                   E(): 6.6e-28, (38.05% identity in 234 aa overlap);
FT                   Q9L4W2|NYSE thioesterase involved in synthesis of the
FT                   polyene antifungal antibiotic nystatin from Streptomyces
FT                   noursei (see citation below) (251 aa), FASTA scores: opt:
FT                   523, E(): 3.8e-27, (34.53% identity in 223 aa overlap);
FT                   Q54145 THIOESTERASE from Streptomyces fradiae (253 aa),
FT                   FASTA scores: opt: 495, E(): 2.7e-25, (37.85% identity in
FT                   230 aa overlap); etc."
FT                   /db_xref="GOA:P63461"
FT                   /db_xref="InterPro:IPR001031"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63461"
FT                   /protein_id="CAD96640.1"
FT                   /translation="MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYV
FT                   AFSREFSADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARIDDPVAFFGHS
FT                   MGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTGMNP
FT                   DFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDR
FT                   TTEEFSIRVFPGDHFYLNDNLPELVSDIEDKTLQWHDRA"
FT   CDS             74543..74854
FT                   /transl_table=11
FT                   /gene="Mb2954"
FT                   /locus_tag="Mb2954"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2954, -, len: 103 aa. Equivalent to Rv2929, len:
FT                   103 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 103 aa overlap). Hypothetical unknown
FT                   protein; unlikely ORF but some weak similarity to
FT                   C-terminal half of P18319|UREG_KLEAE urease accessory
FT                   protein from klebsiella aerogenes (205 aa), FASTA scores:
FT                   opt: 99, E(): 1.1, (38.6% identity in 57 aa overlap)."
FT                   /db_xref="UniProtKB/Swiss-Prot:P65062"
FT                   /protein_id="CAD96641.1"
FT                   /translation="MIELSYAPDVAGRRSNWPKGSGVNTWTAIRWTFAEDSPYVGTGLE
FT                   RMASDTHGGGGGRPVTPPPPGMHHLGCSRGVLLISSQRDAGHKTCDPAAGGTLTSVLT"
FT   CDS             75270..77021
FT                   /transl_table=11
FT                   /gene="fadD26"
FT                   /locus_tag="Mb2955"
FT                   /product="FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA
FT                   SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)"
FT                   /EC_number="6.2.1.-"
FT                   /note="Mb2955, fadD26, len: 583 aa. Equivalent to Rv2930,
FT                   len: 583 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 583 aa overlap). fadD26, fatty-acid-CoA
FT                   synthetase (EC 6.2.1.-) (see first and third citations
FT                   below), equivalent to Q9Z5K5|FADD26|ML2358|MLCB12.03c
FT                   PROBABLE ACYL-CoA SYNTHASE from Mycobacterium leprae (583
FT                   aa), FASTA scores: opt: 3026, E(): 9.2e-180, (76.85%
FT                   identity in 583 aa overlap). Also highly similar to many
FT                   e.g. Q9CD84|ML0132 PUTATIVE ACYL-CoA SYNTHETASE from
FT                   Mycobacterium leprae (680 aa), FASTA scores: opt: 2324,
FT                   E(): 3.2e-136, (61.35% identity in 572 aa overlap); P71495
FT                   ACYL-CoA SYNTHASE from Mycobacterium bovis (582 aa), FASTA
FT                   scores: opt: 2304, E(): 5e-135, (59.85% identity in 583 aa
FT                   overlap); etc. Also highly similar to others from
FT                   Mycobacterium tuberculosis e.g.
FT                   Q50586|FD25_MYCTU|RV1521|MTCY19G5.07 PUTATIVE
FT                   FATTY-ACID--CoA LIGASE (583 aa), FASTA scores: opt: 2188,
FT                   E(): 7.6e-128, (57.55% identity in 584 aa overlap); etc.
FT                   BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY.
FT                   N-terminus shortened since first submission. Note that
FT                   Rv2930|fadD26 belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXM1"
FT                   /db_xref="InterPro:IPR000873"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM1"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96642.1"
FT                   /translation="MPVTDRSVPSLLQERADQQPDSTAYTYIDYGSDPKGFADSLTWSQ
FT                   VYSRACIIAEELKLCGLPGDRVAVLAPQGLEYVLAFLGALQAGFIAVPLSTPQYGIHDD
FT                   RVSAVLQDSKPVAILTTSSVVGDVTKYAASHDGQPAPVVVEVDLLDLDSPRQMPAFSRQ
FT                   HTGAAYLQYTSGSTRTPAGVIVSHTNVIANVTQSMYGYFGDPAKIPTGTVVSWLPLYHD
FT                   MGLILGICAPLVARRRAVLMSPMSFLRRPARWMQLLATSGRCFSAAPNFAFELAVRRTS
FT                   DQDMAGLDLRDVVGIVSGSERIHVATVRRFIERFAPYNLSPTAIRPSYGLAEATLYVAA
FT                   PEAGAAPKTVRFDYEQLTAGQARPCGTDGSVGTELISYGSPDPSSVRIVNPETMVENPP
FT                   GVVGEIWVHGDHVTMGYWQKPKQTAQVFDAKLVDPAPAAPEGPWLRTGDLGVISDGELF
FT                   IMGRIKDLLIVDGRNHYPDDIEATIQEITGGRAAAIAVPDDITEQLVAIIEFKRRGSTA
FT                   EEVMLKLRSVKREVTSAISKSHSLRVADLVLVSPGSIPITTSGKIRRSACVERYRSDGF
FT                   KRLDVAV"
FT   CDS             77018..82648
FT                   /transl_table=11
FT                   /gene="ppsA"
FT                   /locus_tag="Mb2956"
FT                   /product="PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE
FT                   SYNTHASE PPSA"
FT                   /note="Mb2956, ppsA, len: 1876 aa. Equivalent to Rv2931,
FT                   len: 1876 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 1876 aa overlap). ppsA, type-I
FT                   polyketide synthase (see citations below), highly similar
FT                   to others from Mycobacterium leprae e.g.
FT                   Q9Z5K6|ML2357|MLCB12.02c PUTATIVE POLYKETIDE SYNTHASE from
FT                   Mycobacterium leprae (1871 aa), FASTA scores: opt: 7566,
FT                   E(): 0, (76.1% identity in 1888 aa overlap);
FT                   Q9S384|ML2356|MLCB12.01c PUTATIVE POLYKETIDE SYNTHASE from
FT                   Mycobacterium leprae (1540 aa), FASTA scores: opt: 4026,
FT                   E(): 9.8e-212, (45.7% identity in 1811 aa overlap);
FT                   Q49932|PKSC|L518_F1_2 PUTATIVE POLYKETIDE SYNTHASE (1446
FT                   aa), FASTA scores: opt: 4026, E(): 9.4e-212, (70.6%
FT                   identity in 885 aa overlap). Also similar to polyketide
FT                   synthases from other bacteria e.g. C-terminus of
FT                   Q9L8C7|EPOC POLYKETIDE SYNTHASE from Polyangium cellulosum
FT                   (7257 aa), FASTA scores: opt: 2592, E(): 5.2e-133, (32.55%
FT                   identity in 2245 aa overlap); P22367|MSAS_PENPA
FT                   6-methylsalicylic acid synthase from Penicillium patulum
FT                   (Penicillium griseofulvum) (1774 aa), FASTA scores: opt:
FT                   2391, E(): 0, (34.2% identity in 1815 aa overlap); etc. And
FT                   also highly similar to others from Mycobacterium
FT                   tuberculosis e.g. Q10978|PPSB_MYCTU|RV2932 PHENOLPTHIOCEROL
FT                   SYNTHESIS POLYKETIDE SYNTHASE (1538 aa), FASTA scores: opt:
FT                   4227, E(): 0, (46.8% identity in 1810 aa overlap) (gap in
FT                   middle); etc. Contains PS00606 Beta-ketoacyl synthases
FT                   active site, and PS00012 Phosphopantetheine attachment
FT                   site. Note that Rv2931|ppsA belongs to the transcriptional
FT                   unit Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXM0"
FT                   /db_xref="HSSP:1DNY"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXM0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96643.1"
FT                   /translation="MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLADLGVSSRD
FT                   AVVLSGELSELLGRTVSPIDFWEHPTINALAAYLAAPEPSPDSDAAVKRGARNSLDEPI
FT                   AVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQRWQPFEGGPPEVAAALARTTRWG
FT                   SFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFAG
FT                   ACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIH
FT                   LACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGA
FT                   GVVVLKRLTDAQRDGDRVLAVICGSAVTQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQP
FT                   SEVDYVEAHGTGTLLGDPIEARALGTVLGRGRPEDSPLLIGSVKTNLGHTEAAAGIAGF
FT                   IKTVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDTQTEWPATGHPRRAGVSSFGFGG
FT                   TNAHVVIEQGQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALA
FT                   DVAHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPAEGSPGPGTVFVY
FT                   SGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLG
FT                   LIGMQLALTELWCSYGVQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLS
FT                   GQGGMALLELDAPTTEALIADFPQVTLGIYNSPRQTVIAGPTEQIDELITRVRARDRFA
FT                   SRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPVFDAEHWATN
FT                   MRNPVHFQQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQR
FT                   DTDDVVTFRTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYPAGSVGSAPR
FT                   AGTLLGQHTTVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAA
FT                   TELGYSALSEVRFEQPIFADRPRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSS
FT                   SPSDSASSLNEHHRANGQPPERAHRDLIPDLAELLAMRGIDGLPFSWTVASWTQHSSNL
FT                   TVAIDLPEALPEGSTGPLLDAAVHLAALSDVADSRLYVPASIEQISLGDVVTGPRSSVT
FT                   LNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYRALDFGLDVGRAQPPASTGPVEAYCD
FT                   ATNFVHTIDWQPQTVPDATHPGAEQVTHPGPVAIIGDDGAALCETLEGAGYQPAVMSDG
FT                   VSQARYVVYVADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRGVH
FT                   ESVAPSALRQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPSKSIL
FT                   VRRDGVVLAPALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVL
FT                   TGRTPLPPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARD
FT                   RDGAAPIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLT
FT                   ASAAGIFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLGLAADAQLVSEE
FT                   LARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGANAYLLPARNWSVMA
FT                   ATEVRSELEQGLRRIIAAELRVPEKELDTDRPFAELGLNSLMAMAIRREAEQFVGIELS
FT                   ATMLFNHPTVKSLASYLAKRVAPHDVSQDNQISALSSSAGSVLDSLFDRIESAPPEAER
FT                   SV"
FT   CDS             82645..87261
FT                   /transl_table=11
FT                   /gene="ppsB"
FT                   /locus_tag="Mb2957"
FT                   /product="PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE
FT                   SYNTHASE PPSB"
FT                   /note="Mb2957, ppsB, len: 1538 aa. Equivalent to Rv2932,
FT                   len: 1538 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 1538 aa overlap). ppsB, type-I
FT                   polyketide synthase (see citations below), highly similar
FT                   to others from Mycobacterium leprae e.g.
FT                   Q9S384|ML2356|MLCB12.01c PUTATIVE POLYKETIDE SYNTHASE (1540
FT                   aa), FASTA scores: opt: 7284, E(): 0, (76.3% identity in
FT                   1561 aa overlap); Q49932|PKSC|L518_F1_2 PUTATIVE POLYKETIDE
FT                   SYNTHASE (1446 aa), FASTA scores: opt: 6811, E(): 0, (76.2%
FT                   identity in 1462 aa overlap); etc. Also similar to
FT                   polyketide synthases from other bacteria e.g. Q9KIZ6|EPOE
FT                   EPOE PROTEIN from Polyangium cellulosum (3798 aa), FASTA
FT                   scores: opt: 3052, E(): 3.3e-165, (38.35% identity in 1538
FT                   aa overlap); etc. And also highly similar to others from
FT                   Mycobacterium tuberculosis e.g. Q10977|PPSA_MYCTU|RV2931
FT                   PHENOLPTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE (1876 aa),
FT                   FASTA scores: opt: 4227, E(): 0, (46.9% identity in 1810 aa
FT                   overlap); P96203|PPSD|Rv2934|MTCY19H9.02 PKSE PROTEIN (1827
FT                   aa), FASTA scores: opt: 3756, E(): 1.8e-205, (42.9%
FT                   identity in 1808 aa overlap); etc. Overlaps and extends CDS
FT                   from neighbouring cosmid MTCY338.21. Contains PS00606
FT                   Beta-ketoacyl synthases active site. Note that Rv2932|ppsB
FT                   belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL9"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96644.1"
FT                   /translation="MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRF
FT                   PGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGF
FT                   DAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSM
FT                   LAASPQNVDAYSGTGNAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLR
FT                   ETDLALAGGVSITLRPETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLT
FT                   DAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAH
FT                   GTGTVLGDPIEFEALAATYGHGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATI
FT                   PPNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSE
FT                   LAPVSEGGEDTGVSTLVVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRAR
FT                   QATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGR
FT                   QLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELW
FT                   RSYGVQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDA
FT                   AATEALIADYPQVTVGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNP
FT                   AMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIA
FT                   SAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTF
FT                   RTNLYTADIAHPPHTCHPPEPHPTIPTTPWQHTHHWIATTHPSTAAPEDPGSNKVVVNG
FT                   QSTSESRALEDWCHQLAWPIRPAVSADPPSTAAWLVVADNELCHELARAADSRVDSLSP
FT                   PALAAGSDPAALLDALRGVDNVLYAPPVPGELLDIESAYQVFHATRRLAAAMVASSATA
FT                   ISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELA
FT                   VRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRTLPGKPVTLNADASQLVIGATGNIGPH
FT                   LIRQLARMGAKTIVAMARKPGALDELTQCLAATGTDLIAVAADATDPAAMQTLFDRFGT
FT                   ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSS
FT                   VSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAES
FT                   GLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLAAAYRTRGALRIVDDLLPAPEDV
FT                   GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMS
FT                   VTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIGATAVATQQATDSYHE
FT                   LTEAELLEQLSERLRGTQ"
FT   CDS             87258..93824
FT                   /transl_table=11
FT                   /gene="ppsC"
FT                   /locus_tag="Mb2958"
FT                   /product="PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE
FT                   SYNTHASE PPSC"
FT                   /note="Mb2958, ppsC, len: 2188 aa. Equivalent to Rv2933,
FT                   len: 2188 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 2188 aa overlap). ppsC, type-I
FT                   polyketide synthase (see citations below), highly similar
FT                   to others from Mycobacterium leprae e.g.
FT                   Q49933|PKSD|ML2355|L518_F1_3 PUTATIVE POLYKETIDE SYNTHASE
FT                   (2201 aa), FASTA scores: opt: 6973, E(): 0, (82.32%
FT                   identity in 2217 aa overlap);
FT                   Q49624|PKS3|MASA|ML1229|B1170_C2_209 PROBABLE MYCOCEROSIC
FT                   ACID SYNTHASE (2118 aa), FASTA scores: opt: 4015, E():
FT                   2.9e-208, (36.6% identity in 2184 aa overlap); etc. Also
FT                   similar to polyketide synthases from other bacteria e.g.
FT                   C-terminus of Q9L8C7 POLYKETIDE SYNTHASE from Polyangium
FT                   cellulosum (7257 aa), FASTA scores: opt: 3909, E():
FT                   3.6e-202, (40.15% identity in 2220 aa overlap); Q9KIZ7|EPOD
FT                   EPOD PROTEIN from Polyangium cellulosum (7257 aa), FASTA
FT                   scores: opt: 3886, E(): 6.2e-201, (40.05% identity in 2220
FT                   aa overlap); etc. And also highly similar to others from
FT                   Mycobacterium tuberculosis e.g. P96291|Rv2940c (2111 aa),
FT                   FASTA scores: opt: 4204, E(): 0, (39.1% identity in 2176 aa
FT                   overlap); Q10977|PPSA_MYCTU|RV2931 PHENOLPTHIOCEROL
FT                   SYNTHESIS POLYKETIDE SYNTHASE (1876 aa), FASTA scores: opt:
FT                   3793, E(): 2.4e-196, (46.65% identity in 1612 aa overlap);
FT                   etc. Contains PS00606 Beta-ketoacyl synthases active site,
FT                   and PS00012 Phosphopantetheine attachment site. Note that
FT                   Rv2933|ppsC belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL8"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL8"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96645.1"
FT                   /translation="MTAATPDRRAIITEALHKIDDLTARLEIAEKSSSEPIAVIGMGCR
FT                   FPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICSTEGGFLTSWQP
FT                   DEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTSVFVGVTAYDY
FT                   MLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSSLVAVHLACQ
FT                   SLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVRGEGAAVVV
FT                   LKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSKLTAADID
FT                   YVEAHGTGTPLGDPIELDSLSKVFSDRAGSDQLVIGSVKTNLGHLEAAAGVAGLMKAVL
FT                   AVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGVSGTNAHV
FT                   VIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGAAVPLAD
FT                   VAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGTVFVYS
FT                   GRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQIQLGL
FT                   IGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAPLSG
FT                   QGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGFAT
FT                   RVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEHW
FT                   ATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD
FT                   AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPL
FT                   LGVGVTDPTNGTRVWESELDPDLLWLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQD
FT                   QPWMISELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTRSGSSGWTTHATATVARAEP
FT                   LAPLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQ
FT                   VRLPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRF
FT                   AGVHVYGDITRGVRAVGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATE
FT                   LTNRLFMLEWEPAPLEKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELASAAD
FT                   EATLRAAISRTSWDGIVVVCPPRANDESMPDEAQLELARTRTLLVASVVETVTRMGARK
FT                   SPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVLTFEHSELNTTLVDIEPDGTGSLAAL
FT                   AEELLAGSEADEVALRDGQRYVNRLVPAPTTTSGDLAAEARHQVVNLDSSGASRAAVRL
FT                   QIDQPGRLDALNVHEVKRGRPQGDQVEVRVVAAGLNFSDVLKAMGVYPGLDGAAPVIGG
FT                   ECVGYVTAIGDEVDGVEVGQRVIAFGPGTFGTHLGTIADLVVPIPDTLADNEAATFGVA
FT                   YLTAWHSLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMIGARIYTTAGSDAKREMLSR
FT                   LGVEYVGDSRSVDFADEILELTDGYGVDVVLNSLAGEAIQRGVQILAPGGRFIELGKKD
FT                   VYADASLGLAALAKSASFSVVDLDLNLKLQPARYRQLLQHILQHVADGKLEVLPVTAFS
FT                   LHDAADAFRLMASGKHTGKIVISIPQHGSIEAIAAPPPLPLVSRDGGYLIVGGMGGLGF
FT                   VVARWLAEQGAGLIVLNGRSAPSDEVAAAIAELNASGSRIEVITGDITEPDTAERLVRA
FT                   VEDAGFRLAGVVHSAMVLADEIVLNMTDSAARRVFAPKVTGSWRLHVATAARDVDWWLT
FT                   FSSAAALLGTPGQGAYAAANSWVDGLVAHRRSAGLPAVGINWGPWADVGRAQFFKDLGV
FT                   EMINAEQGLAAMQAVLTADRGRTGVFSLDARQWFQSFPAVAGSSLFAKLHDSAARKSGQ
FT                   RRGGGAIRAQLDALDAAERPGHLASAIADEIRAVLRSGDPIDHHRPLETLGLDSLMGLE
FT                   LRNRLEASLGITLPVALVWAYPTISDLATALCERMDYATPAAAQEISDTEPELSDEEMD
FT                   LLADLVDASELEAATRGES"
FT   CDS             93821..99304
FT                   /transl_table=11
FT                   /gene="ppsD"
FT                   /locus_tag="Mb2959"
FT                   /product="PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE
FT                   SYNTHASE PPSD"
FT                   /note="Mb2959, ppsD, len: 1827 aa. Equivalent to Rv2934,
FT                   len: 1827 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 1827 aa overlap). ppsD, type-I
FT                   polyketide synthase (see citations below), highly similar
FT                   to others from Mycobacterium leprae e.g. Q9CB70|ML2354
FT                   POLYKETIDE SYNTHASE (1822 aa), FASTA scores: opt: 9779,
FT                   E(): 0, (80.35% identity in 1836 aa overlap);
FT                   Q49940|L518_F3_67|PFSE (1815 aa), FASTA scores: opt: 9658,
FT                   E(): 0, (79.85% identity in 1831 aa overlap); etc. Also
FT                   similar to polyketide synthases from other bacteria e.g.
FT                   C-terminus of Q9RNB2|MCYD|Q9FDU1 POLYKETIDE SYNTHASE (MCYD
FT                   PROTEIN) from Microcystis aeruginosa (3906 aa), FASTA
FT                   scores: opt: 2961, E(): 6e-159, (32.15% identity in 1827 aa
FT                   overlap); etc. And also highly similar to others from
FT                   Mycobacterium tuberculosis e.g. Q10978|PPSB_MYCTU|RV2932
FT                   PHENOLPTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE (1538 aa),
FT                   FASTA scores: opt: 3756, E(): 3.8e-204, (42.85% identity in
FT                   1808 aa overlap) (gaps in middle); P96202|PPSC|RV2933
FT                   POLYKETIDE SYNTHASE (2188 aa), FASTA scores: opt: 3463,
FT                   E(): 1.7e-187, (39.2% identity in 2165 aa overlap); etc.
FT                   Contains PS00606 Beta-ketoacyl synthases active site,
FT                   PS00017 ATP/GTP-binding site motif A, PS00013 Prokaryotic
FT                   membrane lipoprotein lipid attachment site, and PS00012
FT                   Phosphopantetheine attachment site. Note that Rv2934|ppsD
FT                   belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL7"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96646.1"
FT                   /translation="MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGC
FT                   RFPGNVTGPESFWQLLADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVD
FT                   AFDADFFGITPREAVAMDPQHRILLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYT
FT                   IVNIERRADIDAYLSTGTPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLR
FT                   LRETDVALAGGVQLTLSPFTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKR
FT                   LADAVRDQDRVLAVVRGSATNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVE
FT                   THGTGTVLGDPIEFESLAATYGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLA
FT                   VQRGHIPRNLHFTRWNPAIDASATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVV
FT                   VEQAPDTAVAAAGGMPYVSALNVSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLN
FT                   RHRARHAKFATVIARDRAEAIAGLRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQW
FT                   ASMGQQLLANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLA
FT                   LTELWRSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMAL
FT                   LELDADAAEALIAGYPQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRLARRVEVDV
FT                   ASHHPIIDPILPELRSALADLTPQPPSIPIISTTYESAQPVADADYWSANLRNPVRFHQ
FT                   AVTAAGVDHNTFIEISPHPVLTHALTDTLDPDGSHTVMSTMNRELDQTLYFHAQLAAVG
FT                   VAASEHTTGRLVDLPPTPWHHQRFWVTDRSAMSELAATHPLLGAHIEMPRNGDHVWQTD
FT                   VGTEVCPWLADHKVFGQPIMPAAGFAEIALAAASEALGTAADAVAPNIVINQFEVEQML
FT                   PLDGHTPLTTQLIRGGDSQIRVEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPA
FT                   TGTTVSPADFYALLRQTGQHHGPAFAALSRIVRLADGSAETEISIPDEAPRHPGYRLHP
FT                   VVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCRAHLTNLDGGTG
FT                   KMGRIVLINDAGHIAAEVDGIYLRRVERRAVPLPLEQKIFDAEWTESPIAAVPAPEPAA
FT                   ETTRGSWLVLADATVDAPGKAQAKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAET
FT                   AGDPEHPPVGVVVFVGGASSRLDDELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTG
FT                   GGLSVADDEPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQDPLTALSAELRNAGSG
FT                   SRHDDVIAWRGERRFVERLSRATIDVSKGHPVVRQGASYVVTGGLGGLGLVVARWLVDR
FT                   GAGRVVLGGRSDPTDEQCNVLAELQTRAEIVVVRGDVASPGVAEKLIETARQSGGQLRG
FT                   VVHAAAVIEDSLVFSMSRDNLERVWAPKATGALRMHEATADCELDWWLGFSSAASLLGS
FT                   PGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVGVAQALVGSVLDTISVAEGIE
FT                   ALDSLLAADRIRTGVARLRADRALVAFPEIRSISYFTQVVEELDSAGDLGDWGGPDALA
FT                   DLDPGEARRAVTERMCARIAAVMGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGAR
FT                   ADFGVEPPVALILQGASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAA
FT                   MRRRPKPAVQGG"
FT   CDS             99310..103776
FT                   /transl_table=11
FT                   /gene="ppsE"
FT                   /locus_tag="Mb2960"
FT                   /product="PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE
FT                   SYNTHASE PPSE"
FT                   /note="Mb2960, ppsE, len: 1488 aa. Equivalent to Rv2935,
FT                   len: 1488 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 1488 aa overlap). ppsE, type-I
FT                   polyketide synthase (see citations below), equivalent to
FT                   Q49934|PKSF|ML2353|L518_F1_8 PUTATIVE POLYKETIDE SYNTHASE
FT                   from Mycobacterium leprae (1489 aa), FASTA scores: opt:
FT                   8156, E(): 0, (82.05% identity in 1493 aa overlap). Also
FT                   similar to polyketide synthases from other bacteria e.g.
FT                   Q9RAH3|NOSB NOSB PROTEIN from Nostoc sp. GSV224 (1244 aa),
FT                   FASTA scores: opt: 2438, E(): 8.8e-137, (43.75% identity in
FT                   969 aa overlap); Q9KIZ8|EPOC EPOC PROTEIN from Polyangium
FT                   cellulosum (1832 aa), FASTA scores: opt: 2272, E():
FT                   8.6e-127, (39.95% identity in 1061 aa overlap);
FT                   O54155|SC3F7.12 POLYKETIDE SYNTHASE from Streptomyces
FT                   coelicolor (2297 aa), FASTA scores: opt: 1522, E():
FT                   3.6e-82, (36.35% identity in 1057 aa overlap); etc.
FT                   Contains PS00606 Beta-ketoacyl synthases active site. Note
FT                   that Rv2935|ppsE belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL6"
FT                   /db_xref="HSSP:1DNY"
FT                   /db_xref="InterPro:IPR018201"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96647.1"
FT                   /translation="MSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKESIVTLSEQEL
FT                   RDAGVSDKTLADPAYVRRAPLLDGIDEFDAGFFGFPPLAAQVLDPQHRLFLQCAWHALE
FT                   DAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFL
FT                   ATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYF
FT                   TSPGSMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINND
FT                   GSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFE
FT                   VSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSPNPELRLD
FT                   QSPFVVQSKYGPWECDGVRRAGVSSFGVGGTNAHVVLEEAPAEASEVSAHAEPAGPQVI
FT                   LLSAQTAAALGESRTALAAALETQDGPRLSDVAYTLARRRKHNVTMAAVVHDREHAATV
FT                   LRAAEHDNVFVGEAAHDGEHGDRADAAPTSDRVVFLFPGQGAQHVGMAKGLYDTEPVFA
FT                   QHFDTCAAGFRDETGIDLHAEVFDGTATDLERIDRSQPALFTVEYALAKLVDTFGVRAG
FT                   AYIGYSTGEYIAATLAGVFDLQTAIKTVSLRARLMHESPPGAMVAVALGPDDVTQYLPP
FT                   EVELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQE
FT                   FLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAAPSRIL
FT                   VEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHPLQDVDDRDTFLRALGELWSAGVEVDWT
FT                   PRRPAVPHLVSLPGYPFARQRHWVEPNHTVWAQAPGANNGSPAGTADGSTAATVDAARN
FT                   GESQTEVTLQRIWSQCLGVSSVDRNANFFDLGGDSLMAISIAMAAANEGLTITPQDLYE
FT                   YPTLASLTAAVDASFASSGLAKPPEAQANPAVPPNVTYFLDRGLRDTGRCRVPLILRLD
FT                   PKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEFTGLSNRSVPDGVAAGS
FT                   PEERAAVLGILAELLEDQTDPNAPLAAVHIAAAHGGPHYLCLAIHAMVTDDSSRQILAT
FT                   DIVTAFGQRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTKATLWLA
FT                   DALPNAHTAHPPRADELTKLSSTLSVEQTSELDDGRRRFRRSIQTILLAALGRTIAQTV
FT                   GEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVPLACATGLGALAQLDAVHNTLKS
FT                   VPHYGIGYGLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSGDAPVQFDSDMTLPVR
FT                   EPIPGMGHAIELRVYRFGGSLHLDWWYDTRRIPAATAEALERTFPLALSALIQEAIAAE
FT                   HTEHDDSEIVGEPEAGALVDLSSMDAG"
FT   CDS             103787..104782
FT                   /transl_table=11
FT                   /gene="drrA"
FT                   /locus_tag="Mb2961"
FT                   /product="PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING
FT                   PROTEIN ABC TRANSPORTER DRRA"
FT                   /note="Mb2961, drrA, len: 331 aa. Equivalent to Rv2936,
FT                   len: 331 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 331 aa overlap). Probable drrA,
FT                   daunorubicin-DIM-transport resistance ATP-binding protein
FT                   ABC transporter, probably involved in daunorubicin
FT                   resistance and phthiocerol dimycocerosate transport (see
FT                   citations below), equivalent to
FT                   Q49938|DRRA|ML2352|L518_F2_43|DRRA PROBABLE DAUNORUBICIN
FT                   RESISTANCE ATP-BINDING PROTEIN from Mycobacterium leprae
FT                   (331 aa), FASTA scores: opt: 1842, E(): 4.2e-103, (85.2%
FT                   identity in 331 aa overlap). Also highly similar to others
FT                   e.g. Q9XCF7 DRRA from Mycobacterium avium (315 aa), FASTA
FT                   scores: opt: 1040, E(): 4.7e-55, (54.35% identity in 309 aa
FT                   overlap); Q9X5J8 DAUNORUBICIN RESISTANCE PROTEIN A from
FT                   Mycobacterium avium (315 aa), FASTA scores: opt: 1030, E():
FT                   1.9e-54, (53.7% identity in 309 aa overlap);
FT                   P32010|DRRA_STRPE DAUNORUBICIN RESISTANCE ATP-BINDING
FT                   PROTEIN from Streptomyces peucetius (330 aa), FASTA scores:
FT                   opt: 852, E(): 9e-44, (47.15% identity in 318 aa overlap);
FT                   etc. Contains PS00017 ATP/GTP-binding site motif A
FT                   (P-loop), and PS00211 ABC transporters family signature.
FT                   BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC
FT                   TRANSPORTERS). Note that Rv2936|drrA belongs to the
FT                   transcriptional unit Rv2930|fadD26-Rv2939|papA5 (proven
FT                   experimentaly)."
FT                   /db_xref="GOA:Q7TXL5"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL5"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96648.1"
FT                   /translation="MRNDDMAVVVNGVRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNG
FT                   AGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGVRRSIMVTGQQVAVDDALSGEQNLV
FT                   LFGRLWGLSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGMRRRIDIACGLVVQPQVAF
FT                   LDEPTTGLDPRSRQAIWDLVASFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEG
FT                   TANELKHRAGDTFCEIVPRDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIR
FT                   MLVEAARRIDEARIELADIALRRPSLDDVFLAMTTDPTESLTHLVSGSAR"
FT   CDS             104779..105648
FT                   /transl_table=11
FT                   /gene="drrB"
FT                   /locus_tag="Mb2962"
FT                   /product="PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL
FT                   MEMBRANE PROTEIN ABC TRANSPORTER DRRB"
FT                   /note="Mb2962, drrB, len: 289 aa. Equivalent to Rv2937,
FT                   len: 289 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 289 aa overlap). Probable drrB,
FT                   daunorubicin-DIM-transport integral membrane protein ABC
FT                   transporter, probably involved in daunorubicin resistance
FT                   and phthiocerol dimycocerosate transport (see citations
FT                   below), equivalent to Q49935|DRRB|ML2351|L518_F1_9
FT                   DAUNORUBICIN RESISTANCE TRANSMEMBRANE PROTEIN from
FT                   Mycobacterium leprae (288 aa), FASTA scores: opt: 1252,
FT                   E(): 5.3e-72, (64.0% identity in 289 aa overlap). Also
FT                   similar to others e.g. Q9XCF8 DRRB PROTEIN from
FT                   Mycobacterium avium (246 aa), FASTA scores: opt: 423, E():
FT                   1.5e-19, (30.85% identity in 243 aa overlap); Q9S6H4
FT                   DAUNORUBICIN RESISTANCE PROTEIN B from Mycobacterium avium
FT                   (246 aa), FASTA scores: opt: 420, E(): 2.3e-19, (30.85%
FT                   identity in 243 aa overlap); P32011|DRRB_STRPE DAUNORUBICIN
FT                   RESISTANCE TRANSMEMBRANE PROTEIN from Streptomyces
FT                   peucetius (283 aa), FASTA scores: opt: 242, E(): 4.7e-08,
FT                   (27.85% identity in 219 aa overlap); etc. Note that
FT                   Rv293|drrB belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL4"
FT                   /db_xref="InterPro:IPR004377"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96649.1"
FT                   /translation="MSGPAIDASPALTFNQSSASIQQRRLSTGRQMWVLYRRFAAPSLL
FT                   NGEVLTTVGAPIIFMVGFYIPFAIPWNQFVGGASSGVASNLGQYITPLVTLQAVSFAAI
FT                   GSGFRAATDSLLGVNRRFQSMPMAPLTPLLARVWVAVDRCFTGLVISLVCGYVIGFRFH
FT                   RGALYIVGFCLLVIAIGAVLSFAADLVGTVTRNPDAMLPLLSLPILIFGLLSIGLMPLK
FT                   LFPHWIHPFVRNQPISQFVAALRALAGDTTKTASQVSWPVMAPTLTWLFAFVVILALSS
FT                   TIVLARRP"
FT   CDS             105645..106475
FT                   /transl_table=11
FT                   /gene="drrC"
FT                   /locus_tag="Mb2963"
FT                   /product="PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL
FT                   MEMBRANE PROTEIN ABC TRANSPORTER DRRC"
FT                   /note="Mb2963, drrC, len: 276 aa. Equivalent to Rv2938,
FT                   len: 276 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 276 aa overlap). Probable drrC,
FT                   daunorubicin-DIM-transport integral membrane protein ABC
FT                   transporter, probably involved in daunorubicin resistance
FT                   and phthiocerol dimycocerosate transport (see citations
FT                   below), equivalent to Q9CB71|ML2350 PROBABLE ANTIBIOTIC
FT                   RESISTANCE MEMBRANE PROTEIN from Mycobacterium leprae (276
FT                   aa), FASTA scores: opt: 1434, E(): 1.2e-81, (79.0% identity
FT                   in 276 aa overlap); and Q49941|DRRC|L518_F3_76 PUTATIVE
FT                   DAUNORUBICIN RESISTANCE TRANSMEMBRANE PROTEIN from
FT                   Mycobacterium leprae (244 aa), FASTA scores: opt: 1194,
FT                   E(): 8.3e-67, (76.85% identity in 242 aa overlap). Also
FT                   similar to others e.g. Q9XCF9 DRRC PROTEIN from
FT                   Mycobacterium avium (263 aa), FASTA scores: opt: 538, E():
FT                   3.7e-26, (32.65% identity in 251 aa overlap); Q9S6H3
FT                   DAUNORUBICIN RESISTANCE PROTEIN C from Mycobacterium avium
FT                   (263 aa), FASTA scores: opt: 533, E(): 7.6e-26, (32.25%
FT                   identity in 251 aa overlap); P32011|DRRB_STRPE DAUNORUBICIN
FT                   RESISTANCE TRANSMEMBRANE PROTEIN from Streptomyces
FT                   peucetius (283 aa), FASTA scores: opt: 276, E(): 6.6e-10,
FT                   (21.07% identity in 261 aa overlap); etc. Note that
FT                   Rv2938|drrC belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q7TXL3"
FT                   /db_xref="InterPro:IPR004377"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96650.1"
FT                   /translation="MITTTSQEIELAPTRLPGSQNAARLFVAQTLLQTNRLLTRWARDY
FT                   ITVIGAIVLPILFMVVLNIVLGNLAYVVTHDSGLYSIVPLIALGAAITGSTFVAIDLMR
FT                   ERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLVMLGTGVVLGFRFRQGLIPSLM
FT                   WISVPVILGIAIAAMVTTVALYTAQTVVVEGVELVQAIAIFFSTGLVPLNSYPGWIQPF
FT                   VAHQPVSYAIAAMRGFAMGGPVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH"
FT   CDS             106522..107790
FT                   /transl_table=11
FT                   /gene="papA5"
FT                   /locus_tag="Mb2964"
FT                   /product="POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED
FT                   PROTEIN PAPA5"
FT                   /note="Mb2964, papA5, len: 422 aa. Equivalent to Rv2939,
FT                   len: 422 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 422 aa overlap). Possible papA5,
FT                   conserved polyketide synthase (PKS) associated protein (see
FT                   first citation below), equivalent to Q49939 HYPOTHETICAL
FT                   45.6 KDA PROTEIN from Mycobacterium leprae (423 aa), FASTA
FT                   scores: opt: 2398, E(): 4.5e-144, (84.05% identity in 426
FT                   aa overlap); and Q02279|YMA3_MYCBO HYPOTHETICAL 38.1 KDA
FT                   PROTEIN from Mycobacterium bovis (354 aa), FASTA scores:
FT                   opt: 2193, E(): 3.6e-131, (97.4% identity in 343 aa
FT                   overlap). And C-terminus highly similar to to Q9S381
FT                   HYPOTHETICAL 5.0 KDA PROTEIN (FRAGMENT) from Mycobacterium
FT                   leprae (44 aa), FASTA scores: opt: 275, E(): 1.4e-10,
FT                   (88.65% identity in 44 aa overlap). Also similar in part to
FT                   various synthetases e.g. Q9AE01|RIF20 RIF20 PROTEIN from
FT                   Amycolatopsis mediterranei (Nocardia mediterranei) (403
FT                   aa), FASTA scores: opt: 282, E(): 2.7e-10, (30.3% identity
FT                   in 393 aa overlap); middle part of Q00869|ESYN1 ENNIATIN
FT                   SYNTHETASE (FRAGMENT) (N-methyl peptide synthetase) from
FT                   Fusarium equiseti (3131 aa), FASTA scores: opt: 180, E():
FT                   0.0036, (26.85% identity in 242 aa overlap); N-terminus of
FT                   Q9FB18 PEPTIDE SYNTHETASE NRPS2-1 from Streptomyces
FT                   verticillus (2626 aa), FASTA scores: opt: 159, E(): 0.068,
FT                   (23.65% identity in 351 aa overlap); etc. Note that
FT                   Rv2939|papA5 belongs to the transcriptional unit
FT                   Rv2930|fadD26-Rv2939|papA5 (proven experimentaly)."
FT                   /db_xref="GOA:Q02279"
FT                   /db_xref="InterPro:IPR001242"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q02279"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96651.1"
FT                   /translation="MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDA
FT                   LLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDGTAATNGSPSGNAELRLDQSVSL
FT                   LHLQLILREGGAELTLYLHHCMADGHHGAVLVDELFSRYTDAVTTGDPGPITPQPTPLS
FT                   MEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQAVPVTRLWLSKQQ
FT                   TSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEA
FT                   TNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPP
FT                   LVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEP
FT                   GKSLEAIRSLLCTVPSEYGWIME"
FT   CDS             complement(107953..114288)
FT                   /transl_table=11
FT                   /gene="mas"
FT                   /locus_tag="Mb2965c"
FT                   /product="PROBABLE MULTIFUNCTIONAL MYCOCEROSIC ACID
FT                   SYNTHASE MEMBRANE-ASSOCIATED MAS"
FT                   /note="Mb2965c, mas, len: 2111 aa. Equivalent to Rv2940c,
FT                   len: 2111 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 2111 aa overlap). Probable mas,
FT                   mycocerosic acid synthase membrane associated,
FT                   multifunctional enzyme (see citations below), almost
FT                   identical to Q02251|MCAS_MYCBO|MAS MYCOCEROSIC ACID
FT                   SYNTHASE from Mycobacterium bovis (2110 aa), FASTA scores:
FT                   opt: 13226, E(): 0, (95.8% identity in 2115 aa overlap)
FT                   (see first citation below); and equivalent to
FT                   Q9CD78|MAS|ML0139 PUTATIVE MYCOCEROSIC SYNTHASE from
FT                   Mycobacterium leprae (2116 aa), FASTA scores: opt: 12142,
FT                   E(): 0, (87.95% identity in 2119 aa overlap); and
FT                   Q49624|PKS3|MASA|ML1229|B1170_C2_209 PROBABLE MYCOCEROSIC
FT                   ACID SYNTHASE from Mycobacterium leprae (2118 aa), FASTA
FT                   scores: opt: 8421, E(): 0, (60.8% identity in 2127 aa
FT                   overlap). Also similar to other synthases e.g. C-terminus
FT                   of Q9L8C7|EPOC POLYKETIDE SYNTHASE from Polyangium
FT                   cellulosum (7257 aa), FASTA scores: opt: 4332, E(): 0,
FT                   (40.85% identity in 2149 aa overlap); etc. Also similar to
FT                   others from Mycobacterium tuberculosis e.g.
FT                   O53901|PKS5|Rv1527c|MTV045.01c|MTCY19G5.01 POLYKETIDE
FT                   SYNTHASE (2108 aa), FASTA scores: opt: 5059, E(): 0, (65.9%
FT                   identity in 2121 aa overlap); etc. Contains several
FT                   domains, organized in the following order: beta-ketoacyl
FT                   synthase (PS00606), acyl transferase, dehydratase-enoyl
FT                   reductase, beta-ketoreductase, acyl carrier protein.
FT                   Contains PS00012 Phosphopantetheine attachment site."
FT                   /db_xref="GOA:Q02251"
FT                   /db_xref="HSSP:1E5M"
FT                   /db_xref="InterPro:IPR013149"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q02251"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96652.1"
FT                   /translation="MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDR
FT                   WDADDYYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWE
FT                   AIEHAGLDPASLAGSSTAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHT
FT                   LGLHGPAMTFDTACSSGLMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGML
FT                   SSTGRCHSFDADADGFVRSEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLT
FT                   MPSEDAQVAVYRAALAAAGVQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALG
FT                   SAKSNMGHSTASAGTVGLIKAILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPW
FT                   PNGNDHTPKRVAVSSFGMSGTNVHAIVEEAPAEASAPESSPGDAEVGPRLFMLSSTSSD
FT                   ALRQTARQLATWVEEHQDCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVAD
FT                   GDALYDAAVGHGDRGPVWVFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFS
FT                   VTEAITAQQTVTGIDKVQPAVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGA
FT                   LSLEDAARVICRRSKLMTRIAGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQST
FT                   VIGGTSDTVRDLIARWEQRDVMAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVP
FT                   YYSATLFDPREQPVCDGAYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVE
FT                   QTGRSLDMSVAALAGMRREQPLPHGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAW
FT                   THARLFIDDDGQEQRAQGACTITVHPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQ
FT                   VHNVAALPGAAYCEMALAAAAEVFGEAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVV
FT                   NFTVETNRDGETTRHATAALRAAEDDCPPPGYDITALLQAHPHAVNGTAMRESFAERGV
FT                   TLGAAFGGLTTAHTAEAGAATVLAEVALPASIRFQQGAYRIHPALLDACFQSVGAGVQA
FT                   GTATGGLLLPLGVRSLRAYGPTRNARYCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLA
FT                   VRGLRMGTGTSERDERDRLVSERLLTLGWQQRALPEVGDGEAGSWLLIDTSNAVDTPDM
FT                   LASTLTDALKSHGPQGTECASLSWSVQDTPPNDQAGLEKLGSQLRGRDGVVIVYGPRVG
FT                   DPDEHSLLAGREQVRHLVRITRELAEFEGELPRLFVVTRQAQIVKPHDSGERANLEQAG
FT                   LRGLLRVISSEHPMLRTTLIDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLTPS
FT                   PLGHEERRTAVLDPDHDGMRVQVRRPGDLQTLEFVASDRVPPGPGQIEVAVSMSSINFA
FT                   DVLIAFGRFPIIDDREPQLGMDFVGVVTAVGEGVTGHQVGDRVGGFSEGGCWRTFLTCD
FT                   ANLAVTLPPGLTDEQAITAATAHATAWYGLNDLAQIKAGDKVLIHSATGGVGQAAISIA
FT                   RAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGA
FT                   AQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVREL
FT                   LATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNAEHTGKLVLDVPRSGRRSVAVTPE
FT                   QAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIVLTARSQPNPKARQTIEGLRAAG
FT                   ADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSP
FT                   KVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDVFAHWRRAQGLPV
FT                   SAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRHDRAYSGYIPILGAPWLADL
FT                   VRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRRLLVEQASVILRRTIDADR
FT                   SFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALAQYLADTLAEEQAAAPAA
FT                   S"
FT   CDS             114908..116650
FT                   /transl_table=11
FT                   /gene="fadD28"
FT                   /locus_tag="Mb2966"
FT                   /standard_name="acoas"
FT                   /product="FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA
FT                   SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)"
FT                   /EC_number="6.2.1.-"
FT                   /note="Mb2966, fadD28, len: 580 aa. Equivalent to Rv2941,
FT                   len: 580 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 580 aa overlap). fadD28 (alternate gene
FT                   name: acoas), fatty-acid-CoA synthetase (EC 6.2.1.-) (see
FT                   citations below), almost identical to P71495 ACYL-COA
FT                   SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores:
FT                   opt: 3828, E(): 0, (99.15% identity in 580 aa overlap); and
FT                   equivalent to Q9CD79|FADD28|ML0138 ACYL-COA SYNTHETASE from
FT                   Mycobacterium leprae (579 aa), FASTA scores: opt: 3183,
FT                   E(): 8.8e-186, (81.9% identity in 580 aa overlap). And also
FT                   highly similar to others Mycobacteria proteins e.g.
FT                   O07797|FADD23|Rv3826|MTCY409.04c PUTATIVE FATTY-ACID-COA
FT                   SYNTHETASE from Mycobacterium tuberculosis (584 aa); etc.
FT                   Contains PS00018 EF-hand calcium-binding domain. Note that
FT                   Rv2941|fadD28 and Rv2942|mmpL7 are transcriptionally
FT                   coupled (proven experimentaly)."
FT                   /db_xref="GOA:Q02278"
FT                   /db_xref="InterPro:IPR000873"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q02278"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96653.1"
FT                   /translation="MIVRSLPAALRACARLQPHDPAFTFMDYEQDWDGVAITLTWSQLY
FT                   RRTLNVARELSRCGSTGDRVVISAPQGLEYVVAFLGALQAGRIAVPLSVPQGGVTDERS
FT                   DSVLSDSSPVAILTTSSAVDDVVQHVARRPGESPPSIIEVDLLDLDAPNGYTFKEDEYP
FT                   STAYLQYTSGSTRTPAGVVMSHQNVRVNFEQLMSGYFADTDGIPPPNSALVSWLPFYHD
FT                   MGLVIGICAPILGGYPAVLTSPVSFLQRPARWMHLMASDFHAFSAAPNFAFELAARRTT
FT                   DDDMAGRDLGNILTILSGSERVQAATIKRFADRFARFNLQERVIRPSYGLAEATVYVAT
FT                   SKPGQPPETVDFDTESLSAGHAKPCAGGGATSLISYMLPRSPIVRIVDSDTCIECPDGT
FT                   VGEIWVHGDNVANGYWQKPDESERTFGGKIVTPSPGTPEGPWLRTGDSGFVTDGKMFII
FT                   GRIKDLLIVYGRNHSPDDIEATIQEITRGRCAAISVPGDRSTEKLVAIIELKKRGDSDQ
FT                   DAMARLGAIKREVTSALSSSHGLSVADLVLVAPGSIPITTSGKVRRGACVEQYRQDQFA
FT                   RLDA"
FT   CDS             116643..119405
FT                   /transl_table=11
FT                   /gene="mmpL7"
FT                   /locus_tag="Mb2967"
FT                   /product="CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7"
FT                   /note="Mb2967, mmpL7, len: 920 aa. Equivalent to Rv2942,
FT                   len: 920 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 920 aa overlap). mmpL7, conserved
FT                   transmembrane transport protein (see citations below),
FT                   member of RND superfamily, highly similar to Q9XB10
FT                   HYPOTHETICAL 99.5 KDA PROTEIN from Mycobacterium bovis BCG
FT                   (945 aa), FASTA scores: opt: 488, E(): 4.9e-20, (29.5%
FT                   identity in 918 aa overlap); and to others from
FT                   Mycobacteria e.g. O53735|MML4_MYCTU from Mycobacterium
FT                   tuberculosis (945 aa), FASTA scores: opt: 481, E():
FT                   1.2e-19, (25.9% identity in 922 aa overlap); etc. Also
FT                   similar to other membrane proteins e.g.
FT                   O54101|MMLB_STRCO|SC10A5.10c PUTATIVE MEMBRANE PROTEIN from
FT                   Streptomyces coelicolor (847 aa), FASTA scores: opt: 256,
FT                   E(): 7.2e-07, (25.15% identity in 545 aa overlap); etc.
FT                   Contains PS00639 Eukaryotic thiol (cysteine) proteases
FT                   histidine active site, PS00079 Multicopper oxidases
FT                   signature 1, and PS00044 Bacterial regulatory proteins,
FT                   lysR family signature. BELONGS TO THE MMPL FAMILY. Note
FT                   that Rv2941|fadD28 and Rv2942|mmpL7 are transcriptionally
FT                   coupled (proven experimentaly)."
FT                   /db_xref="GOA:P65371"
FT                   /db_xref="InterPro:IPR004869"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65371"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96654.1"
FT                   /translation="MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLL
FT                   VVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYL
FT                   VVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVW
FT                   LRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVA
FT                   AVIAVLLLLRARLSVRAAAIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLT
FT                   IGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVG
FT                   TAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVL
FT                   AICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHR
FT                   LVEVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIE
FT                   QMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFT
FT                   NCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSA
FT                   LAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHV
FT                   RESMFSSDGTATRLFLYSDGQLDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQI
FT                   AAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYLAALGVSIALWQH
FT                   LLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAA
FT                   LGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR"
FT   repeat_region   119934..119938
FT                   /rpt_type=DIRECT
FT                   /note="5 bp direct repeat, CCGTT, flanking IS element
FT                   IS1533."
FT   repeat_region   119939..119992
FT                   /rpt_type=INVERTED
FT                   /note="54 bp imperfect inverted repeat, IRL,
FT                   TGTCGACGGCACGTGAAAACTGACCCCGGCGCGGCACCCGAATTTTGACCCCCT,
FT                   flanking IS element IS1533."
FT   repeat_region   119939..122151
FT                   /mobile_element="insertion sequence:IS1533"
FT                   /locus_tag="IS1533"
FT                   /note="IS1533, len: 2213 nt. Equivalent to IS1533, len:
FT                   2042 nt, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 2042 nt overlap). Minimum region
FT                   corresponding to IS1533"
FT   CDS             120037..121278
FT                   /transl_table=11
FT                   /gene="Mb2968"
FT                   /locus_tag="Mb2968"
FT                   /product="PROBABLE TRANSPOSASE FOR INSERTION SEQUENCE
FT                   ELEMENT IS1533"
FT                   /note="Mb2968, -, len: 413 aa. Equivalent to Rv2943, len:
FT                   413 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 413 aa overlap). Probable transposase
FT                   for insertion sequence IS1533, similar to other
FT                   transposases e.g. P15025|ISTA_ECOLI ista protein (insertion
FT                   sequence IS21) from Escherichia coli (390 aa), FASTA
FT                   scores: opt: 268, E(): 5.1e-11, (24.1% identity in 378 aa
FT                   overlap). Contains potential helix-turn-helix motif at aa
FT                   19-40 (Score 1611, +4.67 SD)."
FT                   /db_xref="GOA:Q7TXL0"
FT                   /db_xref="InterPro:IPR001584"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXL0"
FT                   /protein_id="CAD96655.1"
FT                   /translation="MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALESNQQP
FT                   KYERAPQGSIVDAVEPRIRELLQAYPTMPATVIAERIGWERSIRVLSARVAELRPVYLP
FT                   PDPASRTTYVAGEIAQCDFWFPPIELPVGFGQTRTAKQLPVLTMVCAYSRWLLAMLLPS
FT                   RCAEDLFAGWWRLIEALGAVPRVLVWDGEGAIGRWRGGRSELTTECQAFRGTLAAKVLI
FT                   CRPADPEAKGLIERAHDYLERSFLPGRVFASPADFNAQLGAWLALVNTRTRRALGCAPT
FT                   DRIGADRAAMLSLPPVAPATGWCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLE
FT                   RVHVFCDGELVADHERIWAVHQTVSDPAHVEAAKVLRRRHFSAASPVVEPQVQVRSLSD
FT                   YDDALGVDIDGGVA"
FT   CDS             121278..121808
FT                   /transl_table=11
FT                   /gene="Mb2969"
FT                   /locus_tag="Mb2969"
FT                   /product="POSSIBLE TRANSPOSASE"
FT                   /note="Mb2969, -, len: 176 aa. Equivalent to Rv2943A, len:
FT                   176 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 176 aa overlap). Possible transposase,
FT                   similar to many e.g. AJ238712|MBO238712_2 PUTATIVE
FT                   TRANSPOSASE (IS21-l) from Mycobacterium bovis BCG (266 aa),
FT                   FASTA scores: opt: 762, E(): 0, (100.0% identity in 118 aa
FT                   overlap). Possible frameshift after codon 118 i.e. near
FT                   position 3290056, to fuse with Rv2944."
FT                   /db_xref="GOA:Q7TXK9"
FT                   /db_xref="InterPro:IPR002611"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK9"
FT                   /protein_id="CAD96656.1"
FT                   /translation="MPTTKATQRRDVSTEIAYLTRALKAPTLRESVSRLADRARAENWS
FT                   HEEYLAACLQREVSARESHGGEGRIRAARFPARKSLEEFDFEHARGLKRDTIAHLGTLD
FT                   FITARDNVVFLGPAWHREDSSCGRPGDTRVSGRSSGAVRHRRRMGSTARRGSPRRAHLR
FT                   RTHPALPLSAPGG"
FT   repeat_region   complement(122098..122151)
FT                   /rpt_type=INVERTED
FT                   /note="54 bp imperfect inverted repeat, IRR,
FT                   TGTCAACGGCACCCGAAAACTGACCCCCTGACGGCATCTGAAAATTGACCCCCT,
FT                   flanking IS element IS1533."
FT   repeat_region   122152..122156
FT                   /rpt_type=DIRECT
FT                   /note="5 bp direct repeat, CCGTT, flanking IS element
FT                   IS1533."
FT   CDS             complement(122197..122898)
FT                   /transl_table=11
FT                   /gene="lppX"
FT                   /locus_tag="Mb2970c"
FT                   /product="PROBABLE CONSERVED LIPOPROTEIN LPPX"
FT                   /note="Mb2970c, lppX, len: 233 aa. Equivalent to Rv2945c,
FT                   len: 233 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 233 aa overlap). Probable lppX,
FT                   conserved lipoprotein, equivalent to Q9CD80 PUTATIVE
FT                   LIPOPROTEIN from Mycobacterium leprae (233 aa), FASTA
FT                   scores: opt: 1165, E(): 2.1e-65, (76.4% identity in 233 aa
FT                   overlap); and similar to Q9CCP6|ML0557 from Mycobacterium
FT                   leprae (238 aa), FASTA scores: opt: 338, E(): 7.4e-14,
FT                   (30.75% identity in 231 aa overlap). Also similar to others
FT                   from Mycobacterium tuberculosis e.g. P71679|LPRG_MYCTU
FT                   LIPOPROTEIN (236 aa), FASTA scores: opt: 342, E(): 4.1e-14,
FT                   (32.05% identity in 231 aa overlap); etc. Contains PS00013
FT                   Prokaryotic membrane lipoprotein lipid attachment site, and
FT                   has in its N-terminal a signal peptide. BELONGS TO THE
FT                   LPPX/LPRAFG FAMILY OF LIPOPROTEINS."
FT                   /db_xref="GOA:P65307"
FT                   /db_xref="InterPro:IPR009830"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65307"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96657.1"
FT                   /translation="MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTA
FT                   SDPALLAEIRQSLDATKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYN
FT                   DEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTE
FT                   VIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLT
FT                   QSKWNEPVNVD"
FT   CDS             complement(123190..129528)
FT                   /transl_table=11
FT                   /gene="pks1"
FT                   /locus_tag="Mb2971c"
FT                   /product="PROBABLE POLYKETIDE SYNTHASE PKS1"
FT                   /note="Mb2971c, pks1, len: 2112 aa. Equivalent to Rv2947c
FT                   and Rv2946c, len: 496 aa and 1616 aa, from Mycobacterium
FT                   tuberculosis strain H37Rv, (99.6% identity in 488 aa
FT                   overlap and 99.9% identity in 1616 aa overlap). Rv2947c:
FT                   Probable pks15, polyketide synthase. Almost identical to
FT                   G560508|Q50469 PKS002B protein from Mycobacterium
FT                   tuberculosis (495 aa), FASTA scores: opt: 3270, E(): 0,
FT                   (99.6% identity in 496 a a overlap). Similar to
FT                   Mycobacterium tuberculosis proteins
FT                   MTCY338.20|RV2931|PPSA_MYCTU ppsA phenolpthiocerol
FT                   synthesis (1876 aa) (49.9% identity in 465 aa overlap);
FT                   MTCY24G1.09|RV2940C|P96291 Putative mas, mycocerosic acid
FT                   synthase (2111 aa) (50.2% identity in 454 aa overlap); and
FT                   MTCY22H8.03|RV2382C|P71718 hypothetical protein (444 aa)
FT                   (47.6% identity in 437 aa overlap). Contains PS00606
FT                   Beta-ketoacyl synthases active site. Rv2946c: Probable
FT                   pks1, polyketide synthase, similar to many e.g.
FT                   ML035|AL583917|Q9CD81 putative polyketide synthase from
FT                   Mycobacterium leprae (2103 aa), Fasta scores: opt: 8761,
FT                   E(): 0, (82.6% identity in 1620 aa overlap); etc. Almost
FT                   identical in part to G560507|Q50470 PKS002C protein from
FT                   Mycobacterium tuberculosis (fragment) (950 aa), Fasta
FT                   scores: opt: 5685, E(): 0, (95.3% identity in 927 aa
FT                   overlap). Also similar to Mycobacterium tuberculosis
FT                   polyketide synthases pks7|Rv1661|P94996 (2126 aa) (54.6%
FT                   identity in 1632 aa); pks12|Rv2048c|O53490 (4151 aa) (58.0%
FT                   identity in 1606 aa); pks8|rv1662|O65933 (1602 aa) (59.7%
FT                   identity in 1144 aa). Contains a PS00012 Phosphopantetheine
FT                   attachment site. REMARK-M.bovis-M.tuberculosis: In
FT                   Mycobacterium tuberculosis H37Rv, pks1 and pks15 exist as 2
FT                   genes. In Mycobacterium bovis, a single base insertion
FT                   (*-g) results in a single product that is more similar to
FT                   pks1."
FT                   /db_xref="GOA:Q7TXK8"
FT                   /db_xref="HSSP:1IYZ"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK8"
FT                   /protein_id="CAD96658.1"
FT                   /translation="MIEEQRTMSVEGADQQSEKLFHYLKKVAVELDETRARLREYEQRA
FT                   TEPVAVVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKT
FT                   YTRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLSLRGSAT
FT                   GVYTGIFAASYGNRDTGGLQGYGLTGTSISVASGRVSYVLGLQGPAVSVDTACSSSLVA
FT                   IHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGE
FT                   GAGVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGL
FT                   SAADVDVVEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAGVA
FT                   GVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSVDGRPRRAAVSSFGI
FT                   SGTNAHLILEEAPVPAPAEAPVEASESTGGPRPSMVPWVISARSAEALTAQAGRLMAHV
FT                   QANPGLDPIDVGCSLASRSVFEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSV
FT                   GKTVVVFPGQGAQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLL
FT                   DSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLTLADAAMLVVA
FT                   RGRLMQALPAGGAMVAVAASEDEVEPLLGEGVGIAAINAPESVVISGAQAAANAIADRF
FT                   AAQGRRVHQLAVSHAFHSPLMEPMLEEFARVAARVQAREPQLGLVSNVTGELAGPDFGS
FT                   AQYWVDHVRRPVRFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGK
FT                   DRPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPGADGPAD
FT                   AAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHVVNGVVLFPGAGFVEL
FT                   VIRAGDEVGCALIEELVLAAPLVMHPGVGVQVQVVVGAADESGHRAVSVYSRGDQSQGW
FT                   LLNAEGMLGVAAAETPMDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQGLVAIWRR
FT                   GSELFAEVVAPGEAGVAVDRMGMHPAVLDAVLHALGLAVEKTQASTETRLPFCWRGVSL
FT                   HAGGAGRVRARFASAGADAISVDVCDATGLPVLTVRSLVTRPITAEQLRAAVTAAGGAS
FT                   DQGPLEVVWSPISVVSGGANGSAPPAPVSWADFCAGSDGDASVVVWELESAGGQASSVV
FT                   GSVYAATHTALEVLQSWLGADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQAE
FT                   NPGRIVLIDTDAAVDASVLAGVGEPQLLVRGGTVHAPRLSPAPALLALPAAESAWRLAA
FT                   GGGGTLEDLVIQPCPEVQAPLQAGQVRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGA
FT                   GVVLETGPEVTDLAVGDAVMGFLGGAGPLAVVDQQLVTRVPQGWSFAQAAAVPVVFLTA
FT                   WYGLADLAEIKAGESVLIHAGTGGVGMAAVQLARQWGVEVFVTASRGKWDTLRAMGFDD
FT                   DHIGDSRTCEFEEKFLAVTEGRGVDVVLDSLAGEFVDASLRLLVRGGRFLEMGKTDIRD
FT                   AQEIAANYPGVQYRAFDLSEAGPARMQEMLAEVRELFDTRELHRLPVTTWDVRCAPAAF
FT                   RFMSQARHIGKVVLTMPSALADRLADGTVVITGATGAVGGVLARHLVGAYGVRHLVLAS
FT                   RRGDRAEGAAELAADLTEAGAKGQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGV
FT                   LDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFVLCSSIAATVGSPGQGNYS
FT                   AANAFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLSSRDLARMSRSGLAPMSPAEA
FT                   VELFDAALAIDHPLAVATLLDRAALDARAQAGALPALFSGLARRPRRRQIDDTGDATSS
FT                   KSALAQRLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVEL
FT                   RNRLKTATGLTLPPTVIFDHPTPTAVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSV
FT                   HA"
FT   CDS             complement(129525..131642)
FT                   /transl_table=11
FT                   /gene="fadD22"
FT                   /locus_tag="Mb2972c"
FT                   /product="PROBABLE FATTY-ACID-CoA LIGASE FADD22
FT                   (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)"
FT                   /EC_number="6.2.1.-"
FT                   /note="Mb2972c, fadD22, len: 705 aa. Equivalent to Rv2948c,
FT                   len: 705 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 705 aa overlap). Probable fadD22,
FT                   fatty-acid-CoA synthetase (EC 6.2.1.-). Highly similar to
FT                   many e.g. Q9CD82|ML0134 putative acyl-CoA synthetase from
FT                   Mycobacterium leprae (707 aa), fasta scores: opt: 3554,
FT                   E(): 6.4e-209, (75.9% identity in 705 aa overlap). Almost
FT                   identical to G560509|Q50468 PKS002A protein from
FT                   Mycobacterium tuberculosis (705 aa), fasta scores: opt:
FT                   4647, E(): 0, (99.7% identity in 705 aa overlap)."
FT                   /db_xref="GOA:Q7TXK7"
FT                   /db_xref="InterPro:IPR009081"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96659.1"
FT                   /translation="MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGE
FT                   VLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPA
FT                   LVVTSDALRDRFQPSRVAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAA
FT                   IHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAP
FT                   VTPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLM
FT                   EFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEG
FT                   DLWVRGPAIAKGYWNRPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVD
FT                   PREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRL
FT                   SAFKVPHRFAVVDRLPRTPNGKLVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSAS
FT                   NMTIAGGNDGGATLRERLVALRQERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELG
FT                   FDSQMTVTLCKRLAAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSG
FT                   ATGLWAIEEQLNKVEELVAVIADGEKQRVADRLRALLGTIAGSEAGLGKLIQAASTPDE
FT                   IFQLIDSELGK"
FT   CDS             complement(131659..132258)
FT                   /transl_table=11
FT                   /gene="Mb2973c"
FT                   /locus_tag="Mb2973c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2973c, -, len: 199 aa. Equivalent to Rv2949c, len:
FT                   199 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 199 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CD83|ML0133 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (210 aa), FASTA scores: opt: 797,
FT                   E(): 7.4e-47, (62.55% identity in 195 aa overlap).
FT                   Equivalent to AAK47348 from Mycobacterium tuberculosis
FT                   strain CDC1551 (212 aa) but shorter 13 aa."
FT                   /db_xref="GOA:Q7TXK6"
FT                   /db_xref="InterPro:IPR002800"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXK6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96660.1"
FT                   /translation="MTECFLSDQEIRKLNRDLRILIAANGTLTRVLNIVADDEVIVQIV
FT                   KQRIHDVSPKLSEFEQLGQVGVGRVLQRYIILKGRNSEHLFVAAESLIAIDRLPAAIIT
FT                   RLTQTNDPLGEVMAASHIETFKEEAKVWVGDLPGWLALHGYQNSRKRAVARRYRVISGG
FT                   QPIMVVTEHFLRSVFRDAPHEEPDRWQFSNAITLAR"
FT   CDS             complement(132284..134143)
FT                   /transl_table=11
FT                   /gene="fadD29"
FT                   /locus_tag="Mb2974c"
FT                   /product="PROBABLE FATTY-ACID-CoA LIGASE FADD29
FT                   (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)"
FT                   /EC_number="6.2.1.-"
FT                   /note="Mb2974c, fadD29, len: 619 aa. Equivalent to Rv2950c,
FT                   len: 619 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 619 aa overlap). Probable fadD29,
FT                   fatty-acid-CoA synthetase (EC 6.2.1.-), similar to various
FT                   mycobacterial enzymes believed to be involved in polyketide
FT                   or fatty acid synthesis. Equivalent (but shorter 61 aa) to
FT                   Q9CD84 from Mycobacterium leprae (680 aa), FASTA scores:
FT                   opt: 3280, E(): 2.2e-192, (80.15% identity in 620 aa
FT                   overlap); and highly similar to others from Mycobacterium
FT                   leprae e.g. Q9Z5K5 PROBABLE ACYL-COA SYNTHASE (583 aa),
FT                   FASTA scores: opt: 2358, E(): 3.4e-136, (62.35% identity in
FT                   579 aa overlap). Also similar to others from Mycobacterium
FT                   tuberculosis e.g. Q10976|FD26_MYCTU PUTATIVE
FT                   FATTY-ACID--CoA LIGASE (583 aa), FASTA scores: opt: 2416,
FT                   E(): 1e-139, (63.15% identity in 581 aa overlap)
FT                   (N-terminus shorter); etc. Equivalent to AAK47349 from
FT                   Mycobacterium tuberculosis strain CDC1551 (582 aa) but
FT                   longer 37 aa."
FT                   /db_xref="GOA:Q7TXK5"
FT                   /db_xref="InterPro:IPR000873"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK5"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96661.1"
FT                   /translation="MKTNSSFHAAGEVATQPAWGTGEQAAQPLNGSTSRFAMSESSLAD
FT                   LLQKAASQYPNRAAYKFIDYDTDPAGFTETVTWWQVHRRAMIVAEELWIYASSGDRVAI
FT                   LAPQGLEYIIAFMGVLQAGLIAVPLPVPQFGIHDERISSALRDSAPSIILTTSSVIDEV
FT                   TTYAPHACAAQGQSAPIVVAVDALDLSSSRALDPTRFERPSTAYLQYTSGSTRAPAGVV
FT                   LSHKNVITNCVQLMSDYIGDSEKVPSTPVSWLPFYHDMGLMLGIILPMINQDTAVLMSP
FT                   MAFLQRPARWMQLLAKHRAQISSAPNFGFELAVRRTSDDDMAGLDLGHVRTIVTGAERV
FT                   NVATLRRFTERFAPFNLSETAIRPSYGLAEATVYVATAGPGRAPKSVCFDYQQLSVGQA
FT                   KRTENGSEGANLVSYGAPRASTVRIVDPETRMENPAGTVGEIWVQGDNVGLGYWRNPQQ
FT                   TEATFRARLVTPSPGTSEGPWLRTGDLGVIFEGELFITGRIKELLVVDGANHYPEDIEA
FT                   TIQEITGGRVVAIAVPDDRTEKLVTIIELMKRGRTDEEEKNRLRTVKREVASAISRSHR
FT                   LRVADVVMVAPGSIPVTTSGKVRRSASVERYLHHEFSRLDAMA"
FT   CDS             complement(134791..135936)
FT                   /transl_table=11
FT                   /gene="Mb2975c"
FT                   /locus_tag="Mb2975c"
FT                   /product="POSSIBLE OXIDOREDUCTASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2975c, -, len: 381 aa. Equivalent to Rv2951c, len:
FT                   381 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 381 aa overlap). Possible
FT                   oxidoreductase (EC 1.-.-.-), equivalent to Q9CD85 PUTATIVE
FT                   OXIDOREDUCTASE from Mycobacterium leprae (382 aa), FASTA
FT                   scores: opt: 2225, E(): 7.6e-134, (84.8% identity in 382 aa
FT                   overlap); and similar to O30260 CONSERVED HYPOTHETICAL
FT                   PROTEIN from Mycobacterium leprae (363 aa), FASTA scores:
FT                   opt: 652, E(): 6.1e-34, (32.55% identity in 344 aa
FT                   overlap). Also similar to various oxidoreductases e.g.
FT                   O29071|AF1196 N5,N10-METHYLENETETRAHYDROMETHANOPTERIN
FT                   REDUCTASE from Archaeoglobus fulgidus (348 aa), FASTA
FT                   scores: opt: 381, E(): 9.7e-17, (27.7% identity in 354 aa
FT                   overlap); Q58929|MER|MJ1534 F420-DEPENDENT
FT                   METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (EC 1.5.99.-)
FT                   from Methanococcus jannaschii (331 aa), FASTA scores: opt:
FT                   372, E(): 3.5e-16, (30.85% identity in 295 aa overlap);
FT                   Q9UXP0 PUTATIVE F420-DEPENDENT
FT                   N5,N10-METHYLENE-TETRAHYDROMETHANOPTERIN REDUCTASE from
FT                   Methanolobus tindarius (326 aa), FASTA scores: opt: 343,
FT                   E(): 2.4e-14, (27.4% identity in 314 aa overlap); etc."
FT                   /db_xref="GOA:Q7TXK4"
FT                   /db_xref="InterPro:IPR016048"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXK4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96662.1"
FT                   /translation="MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLN
FT                   ALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPA
FT                   VTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGE
FT                   LISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDY
FT                   SRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAW
FT                   ARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAE
FT                   WRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL"
FT   CDS             136129..136941
FT                   /transl_table=11
FT                   /gene="Mb2976"
FT                   /locus_tag="Mb2976"
FT                   /product="POSSIBLE METHYLTRANSFERASE (METHYLASE)"
FT                   /EC_number="2.1.1.-"
FT                   /note="Mb2976, -, len: 270 aa. Equivalent to Rv2952, len:
FT                   270 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 270 aa overlap). Probable
FT                   methyltransferase (EC 2.1.1.-), equivalent to Q9CD86|ML0130
FT                   HYPOTHETICAL PROTEIN from Mycobacterium leprae (270 aa),
FT                   FASTA scores: opt: 1584, E(): 6.1e-99, (83.7% identity in
FT                   270 aa overlap). Also highly similar to Q9RMN9|MTF2
FT                   PUTATIVE METHYLTRANSFERASE from Mycobacterium smegmatis
FT                   (274 aa), FASTA scores: opt: 902, E(): 3.8e-53, (56.35%
FT                   identity in 252 aa overlap). Also similar to other
FT                   methyltransferases e.g. Q9ADL4|SORM O-METHYLTRANSFERASE
FT                   from Polyangium cellulosum (346 aa), FASTA scores: opt:
FT                   390, E(): 1.1e-18, (36.25% identity in 251 aa overlap);
FT                   Q54303|RAPM METHYLTRANSFERASE from Streptomyces
FT                   hygroscopicus (317 aa), FASTA scores: opt: 315, E():
FT                   1.1e-13, (40.75% identity in 135 aa overlap); etc. Very
FT                   similar to C-terminal part of Q50584|Rv1523|MTCY19G5.05c
FT                   HYPOTHETICAL 37.9 KDA PROTEIN from Mycobacterium
FT                   tuberculosis (358 aa), FASTA score: opt: 965, E(): 2.7e-57,
FT                   (60.3% identity in 247 aa overlap)."
FT                   /db_xref="GOA:Q7TXK3"
FT                   /db_xref="InterPro:IPR013216"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXK3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96663.1"
FT                   /translation="MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWA
FT                   YEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHP
FT                   ASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRR
FT                   FLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQ
FT                   KSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD"
FT   CDS             136967..138223
FT                   /transl_table=11
FT                   /gene="Mb2977"
FT                   /locus_tag="Mb2977"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2977, -, len: 418 aa. Equivalent to Rv2953, len:
FT                   418 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 418 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CD87|ML0129 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (418 aa), FASTA scores: opt:
FT                   2357, E(): 2.7e-143, (86.6% identity in 418 aa overlap).
FT                   Also highly similar to Q9X7N5|SC5F2A.12c CONSERVED
FT                   HYPOTHETICAL PROTEIN from Streptomyces coelicolor (396 aa),
FT                   FASTA scores: opt: 491, E(): 7e-24, (38.35% identity in 417
FT                   aa overlap); and similar to other hypothetical proteins
FT                   e.g. Q9VG81 CG5167 PROTEIN from Drosophila melanogaster
FT                   (Fruit fly) (431 aa), FASTA scores: opt: 393, E(): 1.4e-17,
FT                   (26.55% identity in 433 aa overlap); Q9GZE9|F22F7.1
FT                   HYPOTHETICAL PROTEIN from Caenorhabditis elegans (426 aa),
FT                   FASTA scores: opt: 338, E(): 4.6e-14, (27.05% identity in
FT                   425 aa overlap); P73855|SLL1601 HYPOTHETICAL 44.8 KDA
FT                   PROTEIN from Synechocystis sp. (strain PCC 6803) (414 aa),
FT                   FASTA scores: opt: 565, E(): 1.3e-28, (35.7% identity in
FT                   409 aa overlap); etc. Also highly similar to other proteins
FT                   from Mycobacterium tuberculosis e.g.
FT                   RV2449C|O53176|MTV008.05C HYPOTHETICAL 44.4 KDA PROTEIN
FT                   (419 aa), FASTA scores: opt: 1835, E(): 7e-110, (67.55%
FT                   identity in 419 aa overlap); etc."
FT                   /db_xref="GOA:Q7TXK2"
FT                   /db_xref="InterPro:IPR005097"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXK2"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96664.1"
FT                   /translation="MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSER
FT                   LRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQVVLTTVGPYTRYGLPLVAACAKA
FT                   GTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVEDGT
FT                   GELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPEL
FT                   GAQPDFLRRPGRDLAPELAGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSL
FT                   GKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTF
FT                   ETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGD
FT                   ALLARLPGAGVVMGTTRLS"
FT   CDS             complement(138354..139079)
FT                   /transl_table=11
FT                   /gene="Mb2978c"
FT                   /locus_tag="Mb2978c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2978c, -, len: 241 aa. Equivalent to Rv2954c, len:
FT                   241 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 241 aa overlap). Hypothetical unknown
FT                   protein. Equivalent to AAK47354 from Mycobacterium
FT                   tuberculosis strain CDC1551 (199 aa) but longer 42 aa."
FT                   /db_xref="InterPro:IPR013217"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK1"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96665.1"
FT                   /translation="MRLPGMLRPTAERHFHSIFYLRHNARRQEHLATLGLDLGNKSVLE
FT                   VGAGIGDHTQFFLDRGCKVLCTEPRGENLDVIRQRFGSNPNVTVDHLDLDGDLPAEAHQ
FT                   YDVVYCYGVLYHLSRPAEALAWMCDRAVDLLLLETCVSYSGEDEPFLVSERASSPSQAI
FT                   TGTGCRPSRVWVMNRLREKMPHVYVTATQPRHRQFPLDWRANGPIASTGLARAVFVASR
FT                   APLNLPTLVEELPMVQRRC"
FT   CDS             complement(139268..140233)
FT                   /transl_table=11
FT                   /gene="Mb2979c"
FT                   /locus_tag="Mb2979c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2979c, -, len: 321 aa. Equivalent to Rv2955c, len:
FT                   321 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 321 aa overlap). Conserved hypothetical
FT                   protein, similar to others e.g. Q98NV5|MLL9724 HYPOTHETICAL
FT                   PROTEIN from Rhizobium loti (Mesorhizobium loti) (284 aa),
FT                   FASTA scores: opt: 231, E(): 6.5e-08, (34.6% identity in
FT                   182 aa overlap); Q9AGG2|NLPE1 NLPE1 from Rhizobium etli
FT                   (249 aa), FASTA scores: opt: 212, E(): 1.1e-06, (27.85%
FT                   identity in 255 aa overlap); Q9KXY2 HYPOTHETICAL 31.3 KDA
FT                   PROTEIN from Streptomyces coelicolor(291 aa), FASTA scores:
FT                   opt: 211, E(): 1.4e-06, (30.9% identity in 249 aa overlap);
FT                   etc."
FT                   /db_xref="InterPro:IPR006342"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXK0"
FT                   /protein_id="CAD96666.1"
FT                   /translation="MQFQDVRLMRVVVCRRLGPAKGQRRWHPLDLGTTGCFENLGAQRP
FT                   TYRMRAIRMLECAMPNRLVRSLQRWRPFGLPPHRWRLAPWYWRGLQVTLEPGSAIAWIV
FT                   RLTGGFEETEIDIAAALYSALYPDRCILDVGANVGIHSLAWARLAPVVALEPAPGTHSR
FT                   LEANVAANGLQDRIRTLRTAAGDAVGEVDFFVAADSAFSSLNDTGRIRIRERTRVPCTT
FT                   LDALAAELPLPVGLLKIDVEGLERAVIAGAAELLRRDRPVLLVEIYGGAASNPDPERTI
FT                   ADIRAYGYEPFVYADDAGLQPYQRHRDDRYCYFFIPSRKG"
FT   CDS             140356..141087
FT                   /transl_table=11
FT                   /gene="Mb2980"
FT                   /locus_tag="Mb2980"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2980, -, len: 243 aa. Equivalent to Rv2956, len:
FT                   243 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 243 aa overlap). Conserved hypothetical
FT                   protein, highly similar to O86299|GSC GSC PROTEIN from
FT                   Mycobacterium avium subsp. silvaticum Mycobacterium avium
FT                   (240 aa), FASTA scores: opt: 1070, E(): 3.5e-63, (67.5%
FT                   identity in 240 aa overlap); and O86294|GSC GSC PROTEIN
FT                   from Mycobacterium paratuberculosis (240 aa), FASTA scores:
FT                   opt: 1070, E(): 3.5e-63, (67.5% identity in 240 aa
FT                   overlap). Also some similarity with other proteins from
FT                   other organisms e.g. Q9L727 NODULATION PROTEIN NOEI from
FT                   Rhizobium fredii (Sinorhizobium fredii) (241 aa), FASTA
FT                   scores: opt: 205, E(): 3.5e-06, (27.25% identity in 198 aa
FT                   overlap); Q9AGG1|LPEA LPEA PROTEIN from Rhizobium etli (286
FT                   aa), FASTA scores: opt: 201, E(): 7.2e-06, (28.85% identity
FT                   in 208 aa overlap); P74191|SLL1173 HYPOTHETICAL 28.0 KDA
FT                   PROTEIN Synechocystis sp. (strain PCC 6803) (244 aa), FASTA
FT                   scores: opt: 274, E(): 1e-10, (30.65% identity in 225 aa
FT                   overlap); etc. Also highly similar to others from
FT                   Mycobacterium tuberculosis e.g. P71792|RV1513|MTCY277.35
FT                   HYPOTHETICAL 26.7 KDA PROTEIN (243 aa), FASTA scores: opt:
FT                   1105, E(): 1.7e-65, (70.05% identity in 237 aa overlap);
FT                   etc."
FT                   /db_xref="InterPro:IPR006342"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ9"
FT                   /protein_id="CAD96667.1"
FT                   /translation="MKSLKLARFIARSAAFEVSRRYSERDLKHQFVKQLKSRRVDVVFD
FT                   VGANSGQYAAGLRRAAYKGRIVSFEPLSGPFTILESKASTDPLWDCRQHALGDSDGTVT
FT                   INIAGNAGQSSSVLPMLKSHQNAFPPANYVGTQEASIHRLDSVAPEFLGMNGVAFLKVD
FT                   VQGFEKQVLAGGKSTIDDHCVGMQLELSFLPLYEGGMLIPEALDLVYSLGFTLTGLLPC
FT                   FIDANNGRMLQADGTFFREDD"
FT   CDS             141158..141985
FT                   /transl_table=11
FT                   /gene="Mb2981"
FT                   /locus_tag="Mb2981"
FT                   /product="POSSIBLE GLYCOSYL TRANSFERASE"
FT                   /EC_number="2.4.1.-"
FT                   /note="Mb2981, -, len: 275 aa. Equivalent to Rv2957, len:
FT                   275 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 275 aa overlap). Possible glycosyl
FT                   transferase (EC 2.4.1.-); possibly secreted protein. Highly
FT                   similar to O88109|GSD|GTFD GSD PROTEIN from Mycobacterium
FT                   avium subsp. silvaticum, Mycobacterium paratuberculosis,
FT                   and Mycobacterium avium (266 aa), FASTA scores: opt: 1010,
FT                   E(): 2.5e-62, (68.8% identity in 221 aa overlap). Also some
FT                   similarity with other proteins and especially glycosyl
FT                   transferases e.g. Q9AEE4 HYPOTHETICAL 31.4 KDA PROTEIN from
FT                   Leptospira interrogans (265 aa), FASTA scores: opt: 371,
FT                   E(): 3.3e-18, (34.43% identity in 212 aa overlap); Q9EXY4
FT                   PUTATIVE GLYCOSYL TRANSFERASE from Escherichia coli (248
FT                   aa), FASTA scores: opt: 339, E(): 5e-16, (32.4% identity in
FT                   210 aa overlap); Q9RCC4 GLYCOSYLTRANSFERASE-LIKE PROTEIN
FT                   from Yersinia pestis (247 aa), FASTA scores: opt: 333, E():
FT                   1.3e-15, (31.8% identity in 217 aa overlap); Q9EXY1
FT                   PUTATIVE GLYCOSYL TRANSFERASE from Escherichia coli (248
FT                   aa), FASTA scores: opt: 328, E(): 2.9e-15, (31.9% identity
FT                   in 210 aa overlap); etc. Equivalent to AAK47357 from
FT                   Mycobacterium tuberculosis strain CDC1551 (256 aa) but
FT                   longer 19 aa."
FT                   /db_xref="GOA:P0A5A0"
FT                   /db_xref="InterPro:IPR001173"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5A0"
FT                   /protein_id="CAD96668.1"
FT                   /translation="MVQTKRYAGLTAANTKKVAMAAPMFSIIIPTLNVAAVLPACLDSI
FT                   ARQTCGDFELVLVDGGSTDETLDIANIFAPNLGERLIIHRDTDQGVYDAMNRGVDLATG
FT                   TWLLFLGADDSLYEADTLARVAAFIGEHEPSDLVYGDVIMRSTNFRWGGAFDLDRLLFK
FT                   RNICHQAIFYRRGLFGTIGPYNLRYRVLADWDFNIRCFSNPALVTRYMHVVVASYNEFG
FT                   GLSNTIVDKEFLKRLPMSTRLGIRLVIVLVRRWPKVISRAMVMRTVISWRRRR"
FT   CDS             complement(142589..143689)
FT                   /transl_table=11
FT                   /gene="Mb2982c"
FT                   /locus_tag="Mb2982c"
FT                   /product="POSSIBLE GLYCOSYL TRANSFERASE [FIRST PART]"
FT                   /EC_number="2.4.1.-"
FT                   /note="Mb2982c, -, len: 366 aa. Similar to 5' end of
FT                   Rv2958c, len: 428 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (83.3% identity in 371 aa overlap). Possible
FT                   glycosyl transferase (EC 2.4.1.-), highly similar to
FT                   Q9CD88|ML0128 PUTATIVE GLYCOSYL TRANSFERASE from
FT                   Mycobacterium leprae (435 aa), FASTA scores: opt: 2116,
FT                   E(): 5.8e-126, (75.05% identity in 417 aa overlap); and
FT                   Q9CD91|ML0125 PUTATIVE GLYCOSYL TRANSFERASE from
FT                   Mycobacterium leprae (438 aa), FASTA scores: opt: 2104,
FT                   E(): 3.3e-125, (74.65% identity in 418 aa overlap). Also
FT                   shows some similarity to variety of glycosyl transferases
FT                   e.g. Q9RYI3 PUTATIVE GLYCOSYLTRANSFERASE from Deinococcus
FT                   radiodurans (418 aa), FASTA scores: opt: 317, E(): 1.9e-12,
FT                   (31.0% identity in 297 aa overlap); Q9S1V2 PUTATIVE
FT                   GLYCOSYL TRANSFERASE from Streptomyces coelicolor (407 aa),
FT                   FASTA scores: opt: 264, E(): 4.1e-09, (27.2% identity in
FT                   342 aa overlap); P72650|CRTX|SLR1125 ZEAXANTHIN GLUCOSYL
FT                   TRANSFERASE from Synechocystis sp. strain PCC 6803 (419
FT                   aa), FASTA scores: opt: 251, E(): 2.8e-08, (26.8% identity
FT                   in 295 aa overlap); etc. Very similar to P95130|MTCY349.25
FT                   from Mycobacterium tuberculosis (449 aa), FASTA score: opt:
FT                   2215, E(): 3.3e-132, (77.25% identity in 422 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
FT                   frameshift due to a single base insertion (*-g) leads to a
FT                   shorter product with a different COOH part compared to its
FT                   homolog in Mycobacterium tuberculosis strain H37Rv."
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXJ8"
FT                   /protein_id="CAD96669.1"
FT                   /translation="MEETSVAGDPGPDAGTSTAPNAAPEPVARRQRILFVGEAATLAHV
FT                   VRPFVLARSLDPSRYEVHFACDPRFNKLLGPLPFPHHPIHTVPSEEVLLKIAQGRLFYN
FT                   TRTLRKYIAADRKILNEIAPDVVVGDNRLSLSVSARLAGIPYIAIANAYWSPQARRRFP
FT                   LPDVPWTRFFGVRPVSILYRLYRPLIFALYCLPLNWLRRKHGLSSLGWDLCRIFTDGDY
FT                   TLYADVPELVPTYNLPANHRYLGPVLWSPDVKPPTWWHSLPTDRPIIYATLGSSGGKNL
FT                   LQVVLNALGRFTRDGDRGHRWPEPPEERAGQRLRRGLPAGRSGCSALRRGALQRRQPDD
FT                   AAGVGGRGAGDRAPQQHGPALEHGGP"
FT   CDS             complement(143790..144527)
FT                   /transl_table=11
FT                   /gene="Mb2983c"
FT                   /locus_tag="Mb2983c"
FT                   /product="POSSIBLE METHYLTRANSFERASE (METHYLASE)"
FT                   /EC_number="2.1.1.-"
FT                   /note="Mb2983c, -, len: 245 aa. Equivalent to Rv2959c, len:
FT                   245 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 245 aa overlap). Possible
FT                   methyltransferase (EC 2.1.1.-), highly similar to
FT                   Q9CD89|ML0127 from Mycobacterium leprae (229 aa), FASTA
FT                   scores: opt: 1183, E(): 3.9e-69, (76.1% identity in 226 aa
FT                   overlap). Also some similarity with other
FT                   methyltransferases and other proteins e.g. Q51079 PUTATIVE
FT                   METHYL TRANSFERASE from Nocardia lactamdurans (236 aa),
FT                   FASTA scores: opt: 156, E(): 0.0086, (23.25% identity in
FT                   159 aa overlap); Q98ID5 CEPHALOSPORIN HYDROXYLASE from
FT                   Rhizobium loti (Mesorhizobium loti) (217 aa), FASTA scores:
FT                   opt: 275, E(): 1.7e-10, (29.65% identity in 199 aa
FT                   overlap); etc. And also similar to P72897 HYPOTHETICAL 27.8
FT                   KDA PROTEIN from Mycobacterium tuberculosis (249 aa), FASTA
FT                   scores: opt: 292, E(): 1.5e-11, (31.25% identity in 208 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7TXJ7"
FT                   /db_xref="InterPro:IPR007072"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXJ7"
FT                   /protein_id="CAD96670.1"
FT                   /translation="MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWY
FT                   YGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFANIMRQI
FT                   GQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAILDS
FT                   DHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDY
FT                   KHDAERENKFGWTSAPNGFLIRN"
FT   CDS             complement(144642..144890)
FT                   /transl_table=11
FT                   /gene="Mb2984c"
FT                   /locus_tag="Mb2984c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2984c, -, len: 82 aa. Equivalent to Rv2960c, len:
FT                   82 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 82 aa overlap). Hypothetical unknown
FT                   protein, equivalent to AAK47362 from Mycobacterium
FT                   tuberculosis strain CDC1551 (116 aa) but shorter 34 aa.
FT                   Shortened version of MTCY349.28 avoiding overlap."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ6"
FT                   /protein_id="CAD96671.1"
FT                   /translation="MGRNATAVVSLPVVALSPRAGQAGYLWQSITRGLRVTPICCYHPP
FT                   CGGGVQKMLSRKLGRVCPAPSPKDAARGAHNVGANAV"
FT   CDS             144972..145361
FT                   /transl_table=11
FT                   /gene="Mb2985"
FT                   /locus_tag="Mb2985"
FT                   /product="PROBABLE TRANSPOSASE"
FT                   /note="Mb2985, -, len: 129 aa. Equivalent to Rv2961, len:
FT                   129 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 129 aa overlap). Probable transposase,
FT                   highly similar to C-terminus of O50414|Rv3387|MTV004.45
FT                   PUTATIVE TRANSPOSASE from Mycobacterium tuberculosis (225
FT                   aa), FASTA scores: opt: 605, E(): 7.2e-34, (66.65% identity
FT                   in 129 aa overlap); and similar to others e.g. CAC47401
FT                   PUTATIVE PARTIAL TRANSPOSASE FOR ISRM17 PROTEIN from
FT                   Rhizobium meliloti (Sinorhizobium meliloti) (174 aa), FASTA
FT                   scores: opt: 183, E(): 2.6e-05, (30.25% identity in 129 aa
FT                   overlap); etc."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ5"
FT                   /protein_id="CAD96672.1"
FT                   /translation="MEHGNPHDAPQLAPAVERITTRAGRPPGTVTADRGYGEKRVEDDL
FT                   HDLGVRTVAIPRKGRPSQARRAEEQRPSFRRTVKWRTGSEGRISTLKRNYGWNRSCIDG
FT                   TEGTRIWTRHGILTHNLIKISSLAA"
FT   CDS             complement(145462..146811)
FT                   /transl_table=11
FT                   /gene="Mb2986c"
FT                   /locus_tag="Mb2986c"
FT                   /product="POSSIBLE GLYCOSYL TRANSFERASE"
FT                   /EC_number="2.4.1.-"
FT                   /note="Mb2986c, -, len: 449 aa. Equivalent to Rv2962c, len:
FT                   449 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 449 aa overlap). Possible glycosyl
FT                   transferase (EC 2.4.1.-), highly similar or identical to
FT                   Mycobacterium tuberculosis proteins G560522 U0002JA,
FT                   G560521 U0002H, G560522 U0002JA, G560519 U0002KA.
FT                   Equivalent (but longer 21 aa) to Q9CD91 PUTATIVE GLYCOSYL
FT                   TRANSFERASE from Mycobacterium leprae (438 aa), FASTA
FT                   scores: opt: 2229, E(): 1.3e-133, (77.45% identity in 426
FT                   aa overlap); and highly similar to Q9CD88 PUTATIVE GLYCOSYL
FT                   TRANSFERASE from Mycobacterium leprae (435 aa), FASTA
FT                   scores: opt: 2129, E(): 2.7e-127, (74.35% identity in 425
FT                   aa overlap); and others from Mycobacterium leprae. Also
FT                   shows some similarity to variety of glycosyl transferases
FT                   e.g. Q9RYI3|DRA0329 PUTATIVE GLYCOSYL TRANSFERASE from
FT                   Deinococcus radiodurans (418 aa), FASTA scores: opt: 340,
FT                   E(): 5.5e-14, (31.2% identity in 330 aa overlap); P72650
FT                   ZEAXANTHIN GLUCOSYL TRANSFERASE from Synechocystis sp.
FT                   (strain PCC 6803) (419 aa), FASTA scores: opt: 244, E():
FT                   6.6e-08, (26.2% identity in 294 aa overlap); etc. Also
FT                   highly similar to P95134 HYPOTHETICAL 46.8 KDA PROTEIN from
FT                   Mycobacterium tuberculosis (428 aa), FASTA scores: opt:
FT                   2215, E(): 9.6e-133, (77.25% identity in 422 aa overlap)."
FT                   /db_xref="GOA:Q7TXJ4"
FT                   /db_xref="InterPro:IPR002213"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXJ4"
FT                   /protein_id="CAD96673.1"
FT                   /translation="MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRI
FT                   LFVAEAVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIPSERF
FT                   FGNLTQGRFYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVSARLAGIPYIAIANA
FT                   YWSPYAQRRFPLPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGW
FT                   NLCRIFTDGDHTLYADVPELMPTYDLPANHEYLGPVLWSPAGKPPTWWDSLPTDRPIVY
FT                   ATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKTVPANAFVADYLPGEAAAARSA
FT                   VVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGA
FT                   VMQVISRSEYRQAAARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS"
FT   CDS             146925..148145
FT                   /transl_table=11
FT                   /gene="Mb2987"
FT                   /locus_tag="Mb2987"
FT                   /product="PROBABLE INTEGRAL MEMBRANE PROTEIN"
FT                   /note="Mb2987, -, len: 406 aa. Equivalent to Rv2963, len:
FT                   406 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 406 aa overlap). Probable integral
FT                   membrane protein."
FT                   /db_xref="InterPro:IPR005524"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ3"
FT                   /protein_id="CAD96674.1"
FT                   /translation="MTSTKVEDRVTAAVLGAIGHALALTASMTWEILWALILGFALSAV
FT                   VQAVVRRSTIVTLLGDDRPRTLVIATGLGAASSSCSYAAVALARSLFRKGANFTAAMAF
FT                   EIGSTNLVVELGIILALLMGWQFTAAEFVGGPIMILVLAVLFRLFVGARLIDAAREQAE
FT                   RGLAGSMEGHAAMDMSIKREGSFWRRLLSPPGFTSIAHVFVMEWLAILRDLILGLLIAG
FT                   AIAAWVPESFWQSFFLANHPAWSAVWGPIIGPIVAIVSFVCSIGNVPLAAVLWNGGISF
FT                   GGVIAFIFADLLILPILNIYRKYYGARMMLVLLGTFYASMVVAGYLIELLFGTTNLIPS
FT                   QRSATVMTAEISWNYTTWLNVIFLVIAAALVVRFITSGGLPMLRMMGGSPDAPHDHHDR
FT                   HDDHLGH"
FT   CDS             148218..149150
FT                   /transl_table=11
FT                   /gene="purU"
FT                   /locus_tag="Mb2988"
FT                   /product="PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU
FT                   (FORMYL-FH(4) HYDROLASE)"
FT                   /EC_number="3.5.1.10"
FT                   /note="Mb2988, purU, len: 310 aa. Equivalent to Rv2964,
FT                   len: 310 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 310 aa overlap). Probable purU,
FT                   formyltetrahydrofolate deformylase (EC 3.5.1.10), highly
FT                   similar to others e.g. Q9RWT1|DR0584 FORMYLTETRAHYDROFOLATE
FT                   DEFORMYLASE from Deinococcus radiodurans (298 aa), FASTA
FT                   scores: opt: 1005, E(): 4.9e-52, (52.25% identity in 297 aa
FT                   overlap); Q9K7U4 FORMYLTETRAHYDROFOLATE DEFORMYLASE from
FT                   Bacillus halodurans (289 aa), FASTA scores: opt: 982, E():
FT                   1.1e-50, (51.8% identity in 280 aa overlap);
FT                   Q55135|PURU_SYNY3|SLL0070 FORMYLTETRAHYDROFOLATE
FT                   DEFORMYLASE from Synechocystis sp. strain PCC 6803 (284
FT                   aa), FASTA scores: opt: 839, E(): 2.9e-42, (48.2% identity
FT                   in 280 aa overlap); etc."
FT                   /db_xref="GOA:P0A5T7"
FT                   /db_xref="InterPro:IPR004810"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5T7"
FT                   /protein_id="CAD96675.1"
FT                   /translation="MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIA
FT                   AVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVADKFG
FT                   IDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLAAHVRPFG
FT                   VPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSF
FT                   LPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGA
FT                   DVERAVLSRAVLWHCQDRVIVHHNQTIVF"
FT   CDS             complement(150019..150504)
FT                   /transl_table=11
FT                   /gene="kdtB"
FT                   /locus_tag="Mb2989c"
FT                   /standard_name="coaD"
FT                   /product="PROBABLE PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
FT                   KDTB (PANTETHEINE-PHOSPHATE ADENYLYLTRANSFERASE) (PPAT)
FT                   (DEPHOSPHO-COA PYROPHOSPHORYLASE)"
FT                   /EC_number="2.7.7.3"
FT                   /note="Mb2989c, kdtB, len: 161 aa. Equivalent to Rv2965c,
FT                   len: 161 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 161 aa overlap). Probable kdtB
FT                   (alternate gene name: coaD), phosphopantetheine
FT                   adenylyltransferase (EC 2.7.7.3), equivalent to
FT                   O69466|COAD_MYCLE PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE
FT                   from Mycobacterium leprae (160 aa), FASTA scores: opt: 881,
FT                   E(): 2.5e-54, (84.1% identity in 157 aa overlap). Also
FT                   highly similar to others e.g. Q9ZBR1|COAD_STRCO from
FT                   Streptomyces coelicolor (159 aa), FASTA scores: opt: 575,
FT                   E(): 5.8e-33, (54.1% identity in 159 aa overlap);
FT                   Q9WZK0|COAD_THEMA from Thermotoga maritima (161 aa), FASTA
FT                   scores: opt: 509, E(): 2.4e-28, (50.0% identity in 154 aa
FT                   overlap); P23875|COAD_ECOLICOAD|KDTB|B3634|Z5058|ECS4509
FT                   from Escherichia coli strain O157:H7 and K12 (159 aa),
FT                   FASTA scores: opt: 459, E(): 7.3e-25, (45.15% identity in
FT                   155 aa overlap); etc. BELONGS TO THE COAD FAMILY."
FT                   /db_xref="GOA:P0A531"
FT                   /db_xref="HSSP:1QJC"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A531"
FT                   /protein_id="CAD96676.1"
FT                   /translation="MTGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMF
FT                   DLDERIAMVKESTTHLPNLRVQVGHGLVVDFVRSCGMTAIVKGLRTGTDFEYELQMAQM
FT                   NKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLRDRLNTERT"
FT   CDS             complement(150590..151156)
FT                   /transl_table=11
FT                   /gene="Mb2990c"
FT                   /locus_tag="Mb2990c"
FT                   /product="POSSIBLE METHYLTRANSFERASE (METHYLASE)"
FT                   /EC_number="2.1.1.-"
FT                   /note="Mb2990c, -, len: 188 aa. Equivalent to Rv2966c, len:
FT                   188 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 188 aa overlap). Possible
FT                   methyltransferase (EC 2.1.1.-), equivalent (but shorter 36
FT                   aa) to O69465|MLCB1243.09 HYPOTHETICAL 23.0 KDA PROTEIN
FT                   from Mycobacterium leprae (220 aa), FASTA scores: opt: 872,
FT                   E(): 9.1e-50, (74.2% identity in 182 aa overlap). Also
FT                   similar to others e.g. Q9ZBR2|SC7A1.11 PUTATIVE METHYLASE
FT                   from Streptomyces coelicolor (195 aa), FASTA scores: opt:
FT                   510, E(): 3.7e-26, (47.5% identity in 179 aa overlap);
FT                   Q9F842 HYPOTHETICAL METHYLTRANSFERASE (FRAGMENT) from
FT                   Mycobacterium smegmatis (80 aa), FASTA scores: opt: 386,
FT                   E(): 2.5e-18, (75.0% identity in 80 aa overlap);
FT                   P10120|YHHF_ECOLI|YHHFZ|B3465 PUTATIVE METHYLASE from
FT                   Escherichia colistrain K12 (198 aa), FASTA scores: opt:
FT                   319, E(): 1.1e-13, (35.5% identity in 183 aa overlap); etc.
FT                   Contains PS00092 N-6 Adenine-specific DNA methylases
FT                   signature."
FT                   /db_xref="GOA:Q7TXJ2"
FT                   /db_xref="InterPro:IPR016065"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ2"
FT                   /protein_id="CAD96677.1"
FT                   /translation="MTRIIGGVAGGRRIAVPPRGTRPTTDRVRESLFNIVTARRDLTGL
FT                   AVLDLYAGSGALGLEALSRGAASVLFVESDQRSAAVIARNIEALGLSGATLRRGAVAAV
FT                   VAAGTTSPVDLVLADPPYNVDSADVDAILAALGTNGWTREGTVAVVERATTCAPLTWPE
FT                   GWRRWPQRVYGDTRLELAERLFANV"
FT   CDS             complement(151352..154735)
FT                   /transl_table=11
FT                   /gene="pca"
FT                   /locus_tag="Mb2991c"
FT                   /product="PROBABLE PYRUVATE CARBOXYLASE PCA (PYRUVIC
FT                   CARBOXYLASE)"
FT                   /EC_number="6.4.1.1"
FT                   /note="Mb2991c, pca, len: 1127 aa. Equivalent to Rv2967c,
FT                   len: 1127 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 1127 aa overlap). Probable pca,
FT                   pyruvate carboxylase (ala-rich protein) (EC 6.4.1.1),
FT                   equivalent to Q9F843|PYC PYRUVATE CARBOXYLASE from
FT                   Mycobacterium smegmatis (1127 aa), FASTA scores: opt: 6232,
FT                   E(): 0, (83.3% identity in 1127 aa overlap). Also highly
FT                   similar to others e.g. Q9RK64|SCF11.26c PYRUVATE
FT                   CARBOXYLASE from Streptomyces coelicolor (1124 aa), FASTA
FT                   scores: opt: 5526, E(): 0, (74.65% identity in 1125 aa
FT                   overlap); O54587|PYC PYRUVATE CARBOXYLASE from
FT                   Corynebacterium glutamicum (Brevibacterium flavum) (1140
FT                   aa), FASTA scores: opt: 4811, E(): 0, (64.5% identity in
FT                   1132 aa overlap); Q9DDT1 PYRUVATE CARBOXYLASE from
FT                   Brachydanio rerio (Zebrafish) (1180 aa), FASTA scores: opt:
FT                   3133, E(): 1.1e-171, (47.8% identity in 1142 aa overlap);
FT                   etc. Contains PS00867 Carbamoyl-phosphate synthase
FT                   subdomain signature 2, PS00165 Serine/threonine
FT                   dehydratases pyridoxal-phosphate attachment site, and
FT                   PS00188 Biotin-requiring enzymes attachment site."
FT                   /db_xref="GOA:Q7TXJ1"
FT                   /db_xref="HSSP:1BNC"
FT                   /db_xref="InterPro:IPR000634"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ1"
FT                   /protein_id="CAD96678.1"
FT                   /translation="MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKA
FT                   DESYQIGDIGHPVHAYLSVDEIVATARRAGADAIYPGYGFLSENPDLAAACAAAGISFV
FT                   GPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAGMPFPLFVKAVAGG
FT                   GGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLEQAVINPRHIEVQILADNLGDVI
FT                   HLYERDCSVQRRHQKVIELAPAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDER
FT                   GEYVFIEMNPRVQVEHTVTEEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQC
FT                   RITTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDL
FT                   PTAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQLLTARASAD
FT                   RGTKILNFLADVTVNNPYGSRPSTIYPDDKLPDLDLRAAPPAGSKQRLVKLGPEGFARW
FT                   LRESAAVGVTDTTFRDAHQSLLATRVRTSGLSRVAPYLARTMPQLLSVECWGGATYDVA
FT                   LRFLKEDPWERLATLRAAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIF
FT                   RIFDALNNIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVD
FT                   AGAHVLAIKDMAGLLRPPAAQRLVSALRSRFDLPVHLHTHDTPGGQLASYVAAWHAGAD
FT                   AVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSAVCALEPYWEALRKVYAPFESG
FT                   LPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSK
FT                   VVGDLALALVGAGVSADEFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGR
FT                   GAARPTAQLAADDEIALSSVGAKRQATLNRLLFPSPTKEFNEHREAYGDTSQLSANQFF
FT                   YGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVRDRSIASAV
FT                   PAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEAPITAPVAGTVE
FT                   RVAVSDTAQVEGGDLLVVVS"
FT   CDS             complement(154760..155392)
FT                   /transl_table=11
FT                   /gene="Mb2992c"
FT                   /locus_tag="Mb2992c"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN"
FT                   /note="Mb2992c, -, len: 210 aa. Equivalent to Rv2968c, len:
FT                   210 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 210 aa overlap). Probable conserved
FT                   integral membrane protein, equivalent to O69464 PUTATIVE
FT                   INTEGRAL MEMBRANE PROTEIN from Mycobacterium leprae (214
FT                   aa), FASTA scores: opt: 1060, E(): 1.4e-58, (71.95%
FT                   identity in 214 aa overlap). Also highly similar to others
FT                   e.g. Q9F844 HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN from
FT                   Mycobacterium smegmatis (187 aa), FASTA scores: opt: 883,
FT                   E(): 1.2e-47, (62.8% identity in 190 aa overlap); Q9KXP3
FT                   PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces
FT                   coelicolor (240 aa), FASTA scores: opt: 503, E(): 4.6e-24,
FT                   (38.0% identity in 192 aa overlap); etc."
FT                   /db_xref="InterPro:IPR012932"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXJ0"
FT                   /protein_id="CAD96679.1"
FT                   /translation="MVAARPAERSGDPAAVRVPVPSAWWVLIGGVIGLFASMTLTVEKV
FT                   RILLDPIYVPSCNVNPIVSCGSVMTTPQASLLGFPNPLLGIAGFTVVVVTGVLAVAKVP
FT                   LPRWYWIGLAVGILVGVAFVHWLIFQSLYRIGALCPYCMVVWAVIATLLVVVASIVFGP
FT                   MRENRGSQERVGARLLYQWRWSLATLWFTTVFLLIMVRFWDYWSTLI"
FT   CDS             complement(155398..156165)
FT                   /transl_table=11
FT                   /gene="Mb2993c"
FT                   /locus_tag="Mb2993c"
FT                   /product="POSSIBLE CONSERVED MEMBRANE OR SECRETED PROTEIN"
FT                   /note="Mb2993c, -, len: 255 aa. Equivalent to Rv2969c, len:
FT                   255 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 255 aa overlap). Possible conserved
FT                   membrane or exported protein, equivalent to Q9CBS4|ML1667
FT                   POSSIBLE CONSERVED MEMBRANE PROTEIN from Mycobacterium
FT                   leprae (264 aa), FASTA scores: opt: 1101, E(): 9.9e-68,
FT                   (65.9% identity in 258 aa overlap); and highly similar to
FT                   O69463 PUTATIVE TRANSMEMBRANE PROTEIN from Mycobacterium
FT                   leprae (258 aa), FASTA scores: opt: 1097, E(): 1.8e-67,
FT                   (65.5% identity in 258 aa overlap). C-terminus also highly
FT                   similar to Q9KK65|996A160 EXPORTED PROTEIN (FRAGMENT) from
FT                   Mycobacterium avium (85 aa), FASTA scores: opt: 418, E():
FT                   2e-21, (72.95% identity in 85 aa overlap). Also weakly
FT                   similar to membrane or exported proteins e.g.
FT                   Q9S2U7|SC4G6.04c PUTATIVE INTEGRAL MEMBRANE PROTEIN from
FT                   Streptomyces coelicolor (275 aa), FASTA scores: opt: 312,
FT                   E(): 7.6e-14, (28.25% identity in 230 aa overlap);
FT                   Q9XAB6|SCC22.22C PUTATIVE SECRETED PROTEIN from
FT                   Streptomyces coelicolor (255 aa), FASTA scores: opt: 181,
FT                   E(): 6.4e-05, (27.0% identity in 226 aa overlap); etc. Also
FT                   some similarity with P72001|PKNE_MYCTU from Mycobacterium
FT                   tuberculosis (566 aa), FASTA scores: opt: 264, E():
FT                   2.3e-10, (30.5% identity in 177 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI9"
FT                   /protein_id="CAD96680.1"
FT                   /translation="MADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVT
FT                   SRDDKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVS
FT                   KLVDIGAVAADYTMVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQP
FT                   AELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGT
FT                   EYEWSTPAALVAKIKEIVGDVPGIDSAAATATS"
FT   CDS             complement(156262..157392)
FT                   /transl_table=11
FT                   /gene="lipN"
FT                   /locus_tag="Mb2994c"
FT                   /product="PROBABLE LIPASE/ESTERASE LIPN"
FT                   /EC_number="3.1.1.-"
FT                   /note="Mb2994c, lipN, len: 376 aa. Equivalent to Rv2970c,
FT                   len: 376 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 376 aa overlap). Probable lipN,
FT                   lipase/esterase (EC 3.1.1.-), similar to others e.g.
FT                   Q9AA37|CC0771 PUTATIVE ESTERASE from Caulobacter crescentus
FT                   (380 aa), FASTA scores: opt: 822, E(): 8e-46, (42.15%
FT                   identity in 318 aa overlap); Q9XDR4 ESTERASE HDE from
FT                   petroleum-degrading bacterium HD-1 (317 aa), FASTA scores:
FT                   opt: 738, E(): 2e-40, (48.85% identity in 262 aa overlap);
FT                   O52270 LIPASE from Pseudomonas sp. (strain B11-1) (308 aa),
FT                   FASTA scores: opt: 683, E(): 7.3e-37, (41.3% identity in
FT                   288 aa overlap); etc. Also similar to P71668 HYPOTHETICAL
FT                   34.1 KDA PROTEIN from Mycobacterium tuberculosis (320 aa),
FT                   FASTA scores: opt: 715, E(): 6.3e-39, (42.3% identity in
FT                   298 aa overlap). Equivalent to AAK47374 from Mycobacterium
FT                   tuberculosis strain CDC1551 (309 aa) but longer 67 aa."
FT                   /db_xref="GOA:Q7TXI8"
FT                   /db_xref="HSSP:1JJI"
FT                   /db_xref="InterPro:IPR013094"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI8"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96681.1"
FT                   /translation="MTKSLPGVADLRLGANHPRMWTRRVQGTVVNVGVKVLPWIPTPAK
FT                   RILSAGRSVIIDGNTLDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAICEAMPGPQ
FT                   IHVDVTDLSIPGPAGEIPARHYRPSGGGATPLLVFYHGGGWTLGDLDTHDALCRLTCRD
FT                   ADIQVLSIDYRLAPEHPAPAAVEDAYAAFVWAHEHASDEFGALPGRVAVGGDSAGGNLS
FT                   AVVCQLARDKARYEGGPTPVLQWLLYPRTDFTAQTRSMGLFGNGFLLTKRDIDWFHTQY
FT                   LRDSDVDPADPRLSPLLAESLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRY
FT                   LGSLTHGFLNLFQLGGGSAAGTNELISALRAHLSRV"
FT   CDS             157623..157793
FT                   /transl_table=11
FT                   /gene="Mb2995"
FT                   /locus_tag="Mb2995"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2995, -, len: 56 aa. Equivalent to Rv2970A, len:
FT                   56 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 56 aa overlap). Conserved hypothetical
FT                   protein, similar to C-terminal part of several
FT                   oxidoreductases e.g. Rv2971|Z83018|MTCY349_22 from
FT                   Mycobacterium tuberculosis (282 aa), FASTA scores: opt:
FT                   158, E(): 3.6e-06, (45.0% identity in 60 aa overlap). May
FT                   represent a gene fragment."
FT                   /protein_id="CAD96682.1"
FT                   /translation="MLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIR
FT                   KPSISQAGEMT"
FT   CDS             157790..158638
FT                   /transl_table=11
FT                   /gene="Mb2996"
FT                   /locus_tag="Mb2996"
FT                   /product="PROBABLE OXIDOREDUCTASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2996, -, len: 282 aa. Equivalent to Rv2971, len:
FT                   282 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 282 aa overlap). Probable oxidoreductase
FT                   (EC 1.-.-.-), possibly aldo/keto reductase, equivalent to
FT                   O69462 PUTATIVE OXIDOREDUCTASE from Mycobacterium leprae
FT                   (282 aa), FASTA scores: opt: 1495, E(): 4.9e-93, (82.35%
FT                   identity in 272 aa overlap). Also similar to others e.g.
FT                   Q9KYM9|SC9H11.10C OXIDOREDUCTASE from Streptomyces
FT                   coelicolor (276 aa), FASTA scores: opt: 849, E(): 1.2e-49,
FT                   (51.7% identity in 267 aa overlap); Q9ZBW7|SC4B5.01C
FT                   PUTATIVE OXIDOREDUCTASE from Streptomyces coelicolor (277
FT                   aa), FASTA scores: opt: 847, E(): 1.7e-49, (49.1% identity
FT                   in 271 aa overlap); Q46857|YQHE_ECOLI|YQHE|B3012
FT                   HYPOTHETICAL OXIDOREDUCTASE from Escherichia coli strain
FT                   K12 (275 aa), FASTA scores: opt: 827, E(): 3.7e-48, (47.45%
FT                   identity in 276 aa overlap); etc. Contains PS00063 Aldo
FT                   /keto reductase family putative active site signature; and
FT                   PS00062 Aldo/keto reductase family signature 2."
FT                   /db_xref="GOA:Q7TXI6"
FT                   /db_xref="HSSP:1HW6"
FT                   /db_xref="InterPro:IPR018170"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXI6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96683.1"
FT                   /translation="MTGESGAAAAPSITLNDEHTMPVLGLGVAELSDDETERAVSAALE
FT                   IGCRLIDTAYAYGNEAAVGRAIAASGVAREELFVTTKLATPDQGFTRSQEACRASLDRL
FT                   GLDYVDLYLIHWPAPPVGKYVDAWGGMIQSRGEGHARSIGVSNFTAEHIENLIDLTFVT
FT                   PAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGRLLDNPTVTSIASEYVKTPAQV
FT                   LLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVREDPLTYAG
FT                   T"
FT   CDS             complement(158712..159425)
FT                   /transl_table=11
FT                   /gene="Mb2997c"
FT                   /locus_tag="Mb2997c"
FT                   /product="POSSIBLE CONSERVED MEMBRANE OR EXPORTED PROTEIN"
FT                   /note="Mb2997c, -, len: 237 aa. Equivalent to Rv2972c, len:
FT                   237 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 237 aa overlap). Possible conserved
FT                   membrane or exported protein, equivalent (but longer 52 aa)
FT                   to O69461|MLCB1243.02 HYPOTHETICAL 20.5 KDA PROTEIN from
FT                   Mycobacterium leprae (180 aa), FASTA scores: opt: 581, E():
FT                   8.2e-32, (55.75% identity in 174 aa overlap). Also similar
FT                   to membrane or exported proteins e.g. Q9F2P3|SCE41.16C
FT                   PUTATIVE LIPOPROTEIN from Streptomyces coelicolor (258 aa),
FT                   FASTA scores: opt: 498, E(): 4.1e-26, (44.08% identity in
FT                   186 aa overlap); Q99QB5|SCP1.323C PUTATIVE SECRETED PROTEIN
FT                   from Streptomyces coelicolor (219 aa), FASTA scores: opt:
FT                   329, E(): 8.5e-15, (36.35% identity in 176 aa overlap);
FT                   Q9ACQ1|SCP1.267 PUTATIVE SECRETED PROTEIN from Streptomyces
FT                   coelicolor (219 aa), FASTA scores: opt: 286, E(): 6.6e-12,
FT                   (32.03% identity in 231 aa overlap); etc."
FT                   /db_xref="InterPro:IPR006311"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI5"
FT                   /protein_id="CAD96684.1"
FT                   /translation="MNRRTLLWLSAIAALALVVAYQTLGSSAGRHADEFAARAGVPTVQ
FT                   PGADVLAGIAVLPKRIHRYDYRRSAFGHPWDDRNDAPGGHNGCDTRDDILDRDLVDKTY
FT                   VSIKRCPNAVATGTLRDPYTNTTVAFQRGASVGQSVQIDHIVPLSYAWDMGAYRWPNSE
FT                   RMRFANDPANLLAVQGQANQDKGDSPPAQWMPPNKAFACQYAMQFIAVLRGYSLPVDQP
FT                   SSDVLRQAAATCPTG"
FT   CDS             complement(159422..161635)
FT                   /transl_table=11
FT                   /gene="recG"
FT                   /locus_tag="Mb2998c"
FT                   /product="PROBABLE ATP-DEPENDENT DNA HELICASE RECG"
FT                   /EC_number="3.6.1.-"
FT                   /note="Mb2998c, recG, len: 737 aa. Equivalent to Rv2973c,
FT                   len: 737 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 737 aa overlap). Probable recG,
FT                   ATP-dependent DNA helicase (EC 3.6.1.-), equivalent to
FT                   O69460|RECG_MYCLE ATP-DEPENDENT DNA HELICASE from
FT                   Mycobacterium leprae (743 aa), FASTA scores: opt: 3846,
FT                   E(): 0, (79.3% identity in 744 aa overlap). Also highly
FT                   similar to others e.g. Q9ZBR3|SC7A1.10 PUTATIVE
FT                   ATP-DEPENDENT DNA HELICASE from Streptomyces coelicolor
FT                   (742 aa), FASTA scores: opt: 1249, E(): 1.1e-67, (46.2%
FT                   identity in 758 aa overlap); Q9PGE8 ATP-DEPENDENT DNA
FT                   HELICASE from Xylella fastidiosa (718 aa), FASTA scores:
FT                   opt: 1174, E(): 3.5e-63, (42.1% identity in 539 aa
FT                   overlap); P24230|RECG_ECOLI|RECG|B3652 from Escherichia
FT                   coli strain K12 (693 aa), FASTA scores: opt: 457, E():
FT                   7.3e-22, (35.2% identity in 733 aa overlap); etc. Contains
FT                   PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO
FT                   THE HELICASE FAMILY, RECG SUBFAMILY."
FT                   /db_xref="GOA:P64323"
FT                   /db_xref="HSSP:1GM5"
FT                   /db_xref="InterPro:IPR004365"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64323"
FT                   /protein_id="CAD96685.1"
FT                   /translation="MASLSDRLDRVLGATAADALDEQFGMRTVDDLLRHYPRSYVEGAA
FT                   RVGIGDARPEAGEHITIVDVITDTYSFPMKKKPNRKCLRITVGGGRNKVTATFFNADYI
FT                   MRDLTKHTKVMLSGEVGYYKGAMQLTHPAFLILDSPDGKNHGTRSLKSIADASKAISGE
FT                   LVVEEFERRFFPIYPASTKVQSWDIFKCVRQVLDVLDRVDDPLPAELRAKHGLIPEDEA
FT                   LRAIHLAESQSLRERARERLTFDEAVGLQWALVARRHGELSESGPSAAWKSNGLAAELL
FT                   RRLPFELTAGQREVLDVLSDGLAANRPLNRLLQGEVGSGKTIVAVLAMLQMVDAGYQCA
FT                   LLAPTEVLAAQHLRSIRDVLGPLAMGGQLGGAENATRVALLTGSMTAGQKKQVRAEIAS
FT                   GQVGIVIGTHALLQEAVDFHNLGMVVVDEQHRFGVEQRDQLRAKAPAGITPHLLVMTAT
FT                   PIPRTVALTVYGDLETSTLRELPLGRQPIATNVIFVKDKPAWLDRAWRRIIEEAAAGRQ
FT                   AYVVAPRIDESDDTDVQGGVRPSATAEGLFSRLRSAELAELRLALMHGRLSADDKDAAM
FT                   AAFRAGEVDVLVCTTVIEVGVDVPNATVMLVMDADRFGISQLHQLRGRIGRGEHPSVCL
FT                   LASWVPPDTPAGQRLRAVAGTMDGFALADLDLKERKEGDVLGRNQSGKAITLRLLSLAE
FT                   HEEYIVAARDFCIEAYKNPTDPALALMAARFTSTDRIEYLDKS"
FT   CDS             complement(161638..163299)
FT                   /transl_table=11
FT                   /gene="Mb2999c"
FT                   /locus_tag="Mb2999c"
FT                   /product="CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN"
FT                   /note="Mb2999c, -, len: 553 aa. Equivalent to Rv2975c and
FT                   Rv2974c, len: 84 aa and 470 aa, from Mycobacterium
FT                   tuberculosis strain H37Rv, (100.0% identity in 83 aa
FT                   overlap and 100.0% identity in 470 aa overlap). Rv2975c:
FT                   Conserved hypothetical protein, similar to N-terminus of
FT                   others e.g. Q9ZBR4|SC7A1.09 HYPOTHETICAL 59.5 KDA PROTEIN
FT                   from Streptomyces coelicolor (589 aa), FASTA scores: opt:
FT                   141, E(): 0.0019, (41.25% identity in 80 aa overlap);
FT                   Q98R49|MYPU_1610 HYPOTHETICAL PROTEIN from Mycoplasma
FT                   pulmonis (545 aa), FASTA scores: opt: 127, E(): 0.023,
FT                   (48.0% identity in 50 aa overlap); Q9K9Z6|BH2498
FT                   HYPOTHETICAL PROTEIN from Bacillus halodurans (557 aa),
FT                   FASTA scores: opt: 126, E(): 0.028, (34.55% identity in 81
FT                   aa overlap); etc. Also some similarity with N-terminus of
FT                   P47609|Y369_MYCGE|MG369 HYPOTHETICAL PROTEIN from
FT                   Mycoplasma genitalium (557 aa), FASTA scores: opt: 108,
FT                   E(): 0.7, (36.75% identity in 49 aa overlap); this, and
FT                   preceding ORF, are similar to Y369_MYCGE and YLOV PROTEIN
FT                   but no cosmid sequence error was identified. Rv2974c:
FT                   Conserved hypothetical ala-rich protein, highly similar to
FT                   others e.g. C-terminus of Q9ZBR4|SC7A1.09 HYPOTHETICAL 59.5
FT                   KDA PROTEIN from Streptomyces coelicolor (589 aa), FASTA
FT                   scores: opt: 774, E(): 1.3e-36, (41.0% identity in 495 aa
FT                   overlap); Q9K9Z6|BH2498 HYPOTHETICAL PROTEIN from Bacillus
FT                   halodurans (557 aa), FASTA scores: opt: 268, E(): 8e-08,
FT                   (27.7% identity in 502 aa overlap) (N-terminus longer 76
FT                   aa); Q9X293 CONSERVED HYPOTHETICAL PROTEIN from Thermotoga
FT                   maritima (497 aa), FASTA scores: opt: 265, E(): 1.1e-07,
FT                   (24.9% identity in 470 aa overlap) (N-terminus longer 43
FT                   aa); etc. Also some similarity with P47609|Y369_MYCGE|MG369
FT                   HYPOTHETICAL PROTEIN from Mycoplasma genitalium (557 aa),
FT                   FASTA scores: opt: 154, E(): 0.25, (20.25% identity in 489
FT                   aa overlap); this, and following ORF, are similar to
FT                   Y369_MYCGE but no cosmid sequence error was identified.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis H37Rv, Rv2975c and Rv2974c exist as 2 genes.
FT                   In Mycobacterium bovis, a 2 bp deletion (cg-*) results in a
FT                   single product that is more similar to Rv2974c."
FT                   /db_xref="GOA:Q7TXI4"
FT                   /db_xref="InterPro:IPR019986"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI4"
FT                   /protein_id="CAD96686.1"
FT                   /translation="MGTADRPLDASALRDWAHAVVSDLILHIDEINRLNVFPVADSDTG
FT                   VNMLFTMRAAVVEADLHANSQADAEDVARVAAALAAGALNGARGNSGVILSQILRGIAE
FT                   VTATAAAASGAVLRAVDANALGAALWRGVELVVASMGGVEVPGTIVSVLRAAAGAVDQC
FT                   AHEGLAGAVTAAGDAAVIALEKTPEQLDVLADAGAVDAGGRGLLVLLDALRSTICGQAP
FT                   ARAVYEPSPRALPTDTATQRPAPQFEVMYLLAVCDAAAADQLRDRLKELGESVAIAAAP
FT                   PDSYSVHVHTDDAGAAVEAGLAVGRVSRIVISALGSGTSGLPAGGWTRGRAVLAVVDGD
FT                   GAAELFAGEGACVLRPGPDAVTPAADISAHQLVRAVVDTGAAHVMVLPNGYVAAEELVA
FT                   GCTAAIGWGVDVVPVPTGSMVQGLAALAVHDAARQAVDDGYSMARAAGASRHGSVRIAT
FT                   QKALTWAGTCKPGDGLGIAGDEVLIVADDVAAAAIGLVDLLLASGGDLVTVLIGAGVTE
FT                   DVAVVLERHVHDHHPGTELVSYRTGHRGDALLIGVE"
FT   CDS             complement(163758..164441)
FT                   /transl_table=11
FT                   /gene="ung"
FT                   /locus_tag="Mb3000c"
FT                   /product="PROBABLE URACIL-DNA GLYCOSYLASE UNG (UDG)"
FT                   /EC_number="3.2.2.-"
FT                   /note="Mb3000c, ung, len: 227 aa. Equivalent to Rv2976c,
FT                   len: 227 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 227 aa overlap). Probable ung,
FT                   uracil-DNA glycosylase (EC 3.2.2.-), equivalent to Q9CBS3
FT                   URACIL-DNA GLYCOSYLASE from Mycobacterium leprae (227 aa),
FT                   FASTA scores: opt: 1394, E(): 8.8e-85, (88.1% identity in
FT                   227 aa overlap). Also highly similar to others e.g. Q9EX12
FT                   from Streptomyces coelicolor (225 aa), FASTA scores: opt:
FT                   1134, E(): 1.3e-67, (72.75% identity in 224 aa overlap);
FT                   Q9K682|UNG_BACHD from Bacillus halodurans (224 aa), FASTA
FT                   scores: opt: 652, E(): 8.9e-36, (45.5% identity in 222 aa
FT                   overlap); P39615|UNG_BACSU from Bacillus subtilis (225 aa),
FT                   FASTA scores: opt: 625, E(): 5.4e-34, (45.5% identity in
FT                   222 aa overlap); etc. BELONGS TO THE URACIL-DNA GLYCOSYLASE
FT                   FAMILY."
FT                   /db_xref="GOA:P67072"
FT                   /db_xref="HSSP:3EUG"
FT                   /db_xref="InterPro:IPR005122"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67072"
FT                   /protein_id="CAD96687.1"
FT                   /translation="MTARPLSELVERGWAAALEPVADQVAHMGQFLRAEIAAGRRYLPA
FT                   GSNVLRAFTFPFDNVRVLIVGQDPYPTPGHAVGLSFSVAPDVRPWPRSLANIFDEYTAD
FT                   LGYPLPSNGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEAVTECAIRALAARAAPL
FT                   VAILWGRDASTLKPMLAAGNCVAIESPHPSPLSASRGFFGSRPFSRANELLVGMGAEPI
FT                   DWRLP"
FT   CDS             complement(164474..165475)
FT                   /transl_table=11
FT                   /gene="thiL"
FT                   /locus_tag="Mb3001c"
FT                   /product="PROBABLE THIAMINE-MONOPHOSPHATE KINASE THIL
FT                   (THIAMINE-PHOSPHATE KINASE)"
FT                   /EC_number="2.7.4.16"
FT                   /note="Mb3001c, thiL, len: 333 aa. Equivalent to Rv2977c,
FT                   len: 333 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 333 aa overlap). Possible thiL,
FT                   thiamin-monophosphate kinase (EC ), equivalent to Q9CBS2
FT                   PROBABLE THIAMINE-MONOPHOSPHATE KINASE from Mycobacterium
FT                   leprae (325 aa), FASTA scores: opt: 1738, E(): 4.5e-98,
FT                   (80.9% identity in 314 aa overlap). Also highly similar to
FT                   others e.g. Q9ZBR7|SC7A1.06 PUTATIVE THIAMINE MONPHOSPHATE
FT                   KINASE from Streptomyces coelicolor (322 aa), FASTA scores:
FT                   opt: 959, E(): 7.8e-51, (51.1% identity in 319 aa overlap);
FT                   O05514|THIL_BACSU THIAMINE-MONOPHOSPHATE KINASE from
FT                   Bacillus subtilis (325 aa), FASTA scores: opt: 476, E():
FT                   1.5e-21, (35.15% identity in 273 aa overlap);
FT                   P77785|THIL_ECOLI|THIL|B0417 THIAMINE-MONOPHOSPHATE KINASE
FT                   from Escherichia coli strain K12 (325 aa), FASTA scores:
FT                   opt: 418, E(): 5e-18, (36.9% identity in 282 aa overlap);
FT                   etc. BELONGS TO THE THIAMINE-MONOPHOSPHATE KINASE FAMILY.
FT                   Note that the start, as given, is in IS1538."
FT                   /db_xref="GOA:Q7TXI3"
FT                   /db_xref="InterPro:IPR006283"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI3"
FT                   /protein_id="CAD96688.1"
FT                   /translation="MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDA
FT                   ALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFVVGF
FT                   GAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVLRS
FT                   GAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAM
FT                   IDVSDGLLADLRHIAEASGVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHA
FT                   LVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGWQSFGEPDNQGSLG"
FT   repeat_region   165455..165460
FT                   /rpt_type=INVERTED
FT                   /note="6 bp perfect inverted repeat, IRR, TGAGTG, flanking
FT                   IS element IS1538."
FT   repeat_region   complement(165455..167479)
FT                   /mobile_element="insertion sequence:IS1538"
FT                   /locus_tag="IS1538"
FT                   /note="IS1538, len: 2025 nt. Equivalent to IS1538, len:
FT                   2025 nt, from Mycobacetrium tuberculosis strain H37Rv,
FT                   (99.9% identity in 2025 nt overlap). Similar to other IS
FT                   elements in Mycobacterium tuberculosis e.g. IS1535, IS1536,
FT                   IS1537, & IS1539 (EM_NEW:MTCY274 Z74024 Mycobacterium
FT                   tuberculosis cosmid Y274)"
FT   CDS             complement(165472..166851)
FT                   /transl_table=11
FT                   /gene="Mb3002c"
FT                   /locus_tag="Mb3002c"
FT                   /product="PROBABLE RESOLVASE"
FT                   /note="Mb3002c, -, len: 459 aa. Equivalent to Rv2978c, len:
FT                   459 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 459 aa overlap). Probable resolvase for
FT                   IS1538, with low level matches to transposon resolvases;
FT                   highly similar from aa 101 to YX1C_MYCTU|Q10831 from
FT                   Mycobacterium tuberculosis (295 aa), FASTA scores: opt:
FT                   809, E(): 0, (69.1% identity in 194 aa overlap). Contains
FT                   PS00397 Site-specific recombinases active site, and
FT                   possible helix-turn-helix motiv at aa 2-23."
FT                   /db_xref="InterPro:IPR010095"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI2"
FT                   /protein_id="CAD96689.1"
FT                   /translation="MPKFEVPDGWTVQAFRFTLDPTEDQAKALARHFGARRKAYNWTVA
FT                   TLKADIQAWHASGTVTAKPSLRVLRKRWNTVKDDVCVNTETGVAWWPECSKEAYADGIA
FT                   GAVEAYWNWQTSRAGKRAGKRVGFPRFKRKGRDQDRVSFTTGAMRVEPDRRHLTLPVIG
FT                   TVRTHENTRRIERLIKAGRARVLAISVRRNGTRLDASVRVLVQRPQQPKVVHPGSRVGV
FT                   DVGVRRLATVATADGTAIEQVENPRPLGAALRELRHVCRARSRCTKGSRRYRERTTQIS
FT                   RLHRRVNDVRTHHLHVLTTRLAQTHGRIVVEGLDATEMLRQKGLPGARARRRGLSDAAL
FT                   GTPRRHLSYKTVWYGSALVVADRWFPSSKTCHACRHVQDIGWDEQWQCDRCSVVHQRDD
FT                   CAAINLARYEETSSIVGPVGAAVKRGADRKTGPRPAGGCEARKGSSPKAAEQPRDGVQV
FT                   A"
FT   CDS             complement(166851..167435)
FT                   /transl_table=11
FT                   /gene="Mb3003c"
FT                   /locus_tag="Mb3003c"
FT                   /product="PROBABLE RESOLVASE"
FT                   /note="Mb3003c, -, len: 194 aa. Equivalent to Rv2979c, len:
FT                   194 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (98.5% identity in 194 aa overlap). Probable resolvase for
FT                   IS1538, with low level matches to transposon resolvases;
FT                   highly similar from aa 101 to YX1C_MYCTU|Q10831 from
FT                   Mycobacterium tuberculosis (295 aa), FASTA scores: opt:
FT                   809, E(): 0, (69.1% identity in 194 aa overlap). Contains
FT                   PS00397 Site-specific recombinases active site, and
FT                   possible helix-turn-helix motiv at aa 2-23."
FT                   /db_xref="GOA:Q7TXI1"
FT                   /db_xref="InterPro:IPR006119"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI1"
FT                   /protein_id="CAD96690.1"
FT                   /translation="MNLATWAERNGVARGTAYRWFRAGLLSVMARRVGRLILVDEPAGD
FT                   AGMRSPTAVYARVSSADQKADLDRQVARVTAWAAAQQMPVDKVVTEVGSAFNEHRRKFL
FT                   SLLRDPSVHRIVVEHRDRFCRLGSKYVQAAFAAQGRELVVVDSAEVGDDLVRDMTEILT
FT                   SMCARLYGKRAAENRTKRALAAAAGEDHEAA"
FT   repeat_region   complement(167474..167479)
FT                   /rpt_type=INVERTED
FT                   /note="6 bp perfect inverted repeat, IRL, TGAGTG, flanking
FT                   IS element IS1538."
FT   CDS             167647..168192
FT                   /transl_table=11
FT                   /gene="Mb3004"
FT                   /locus_tag="Mb3004"
FT                   /product="POSSIBLE CONSERVED SECRETED PROTEIN"
FT                   /note="Mb3004, -, len: 181 aa. Equivalent to Rv2980, len:
FT                   181 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 181 aa overlap). Possible conserved
FT                   secreted protein, equivalent to Q9CBS1 POSSIBLE SECRETED
FT                   PROTEIN from Mycobacterium leprae (191 aa), FASTA scores:
FT                   opt: 794, E(): 2.3e-40, (67.25% identity in 177 aa
FT                   overlap). Also some weak similarity with other hypothetical
FT                   proteins or secreted proteins e.g. C-terminus of
FT                   Q98F98|MLL3872 MLL3872 PROTEIN from Rhizobium loti
FT                   (Mesorhizobium loti) (575 aa), FASTA scores: opt: 148, E():
FT                   0.16, (28.35% identity in 194 aa overlap);
FT                   Q9L0W9|SCH22A.13C PUTATIVE SECRETED PROTEIN from
FT                   Streptomyces coelicolor (167 aa), FASTA scores: opt: 114,
FT                   E(): 7.5, (40.0% identity in 80 aa overlap); etc.
FT                   Equivalent to AAK47385 from Mycobacterium tuberculosis
FT                   strain CDC1551 (214 aa) but shorter 33 aa. Has hydrophobic
FT                   stretch near N-terminus."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXI0"
FT                   /protein_id="CAD96691.1"
FT                   /translation="MTGESDGPPRAVLIAAAALAAAVIGVILVVAANRQPPERPVVIPA
FT                   VPAPQATGPGCKALLAALPQRLGEYRRAPVAEPTTAGATAWRTGPNSTPVILRCGLDRP
FT                   AEFVVGSAIQVVDRVQWFQVAAQNPDEPGRSTWYTVDRPVYVALTLPSGSGPTAIQELS
FT                   DVIDHTIPAVPIDPAPAR"
FT   CDS             complement(168365..169477)
FT                   /transl_table=11
FT                   /gene="ddlA"
FT                   /locus_tag="Mb3005c"
FT                   /standard_name="ddl"
FT                   /product="PROBABLE D-ALANINE--D-ALANINE LIGASE DDLA
FT                   (D-ALANYLALANINE SYNTHETASE) (D-ALA-D-ALA LIGASE)"
FT                   /EC_number="6.3.2.4"
FT                   /note="Mb3005c, ddlA, len: 370 aa. Equivalent to Rv2981c,
FT                   len: 373 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (98.9% identity in 373 aa overlap). Probable ddlA
FT                   (alternate gene name: ddl), D-alanine--D-alanine ligase A
FT                   (EC 6.3.2.4), equivalent to Q9CBS0|Q9CBS0
FT                   D-ALANINE-D-ALANINE LIGASE A from Mycobacterium leprae (384
FT                   aa), FASTA scores: opt: 2001, E(): 2.4e-115, (81.75%
FT                   identity in 367 aa overlap); and Q9ZGN0|DDL_MYCSM
FT                   D-ALANINE--D-ALANINE LIGASE from Mycobacterium smegmatis
FT                   (373 aa), FASTA scores: opt: 1934, E(): 3.1e-111, (77.95%
FT                   identity in 372 aa overlap). Also highly similar to others
FT                   e.g. Q9ZBR9|DDL_STRCO from Streptomyces coelicolor (389
FT                   aa), FASTA scores: opt: 1187, E(): 2.2e-65, (52.0% identity
FT                   in 379 aa overlap); P15051|DDLA_SALTY from Salmonella
FT                   typhimurium and Salmonella typhi (363 aa), FASTA scores:
FT                   opt: 946, E(): 1.3e-50, (44.5% identity in 364 aa overlap);
FT                   P23844|DDLA_ECOLI|DDLA|B0381|Z0477|ECS0431 from Escherichia
FT                   coli strain O157:H7 and K12 (364 aa), FASTA scores: opt:
FT                   938, E(): 3.9e-50, (43.55% identity in 363 aa overlap);
FT                   etc. Contains PS00843 D-alanine--D-alanine ligase signature
FT                   1. BELONGS TO THE D-ALANINE--D-ALANINE LIGASE FAMILY.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 9
FT                   bp deletion (acgccggtc-*) leads to a shorter product
FT                   compared to its homolog in Mycobacterium tuberculosis
FT                   strain H37Rv (370 aa versus 373 aa)."
FT                   /db_xref="GOA:Q7TXH9"
FT                   /db_xref="InterPro:IPR013817"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXH9"
FT                   /protein_id="CAD96692.1"
FT                   /translation="MSANDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAV
FT                   GITPAGSWVLTDANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVL
FT                   ESVDVVFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPV
FT                   GAYAVLRPPRSTLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDP
FT                   KVIVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAEL
FT                   DVPAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMY
FT                   PRMWAASGVDYPTLLATMIETALARGVGLH"
FT   CDS             complement(169555..170559)
FT                   /transl_table=11
FT                   /gene="gpdA2"
FT                   /locus_tag="Mb3006c"
FT                   /standard_name="gpsA"
FT                   /product="PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE
FT                   [NAD(P)+] GPDA2 (NAD(P)H-DEPENDENT GLYCEROL-3-PHOSPHATE
FT                   DEHYDROGENASE)"
FT                   /EC_number="1.1.1.94"
FT                   /note="Mb3006c, gpdA2, len: 334 aa. Equivalent to Rv2982c,
FT                   len: 334 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 334 aa overlap). Probable gpdA2
FT                   (alternate gene name: gpsA), glycerol-3-phosphate
FT                   dehydrogenase [NAD(P)+] (EC 1.1.1.94), equivalent to
FT                   Q9CBR9|GPDA_MYCLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE
FT                   [NAD(P)+] from Mycobacterium leprae (349 aa), FASTA scores:
FT                   opt: 1686, E(): 1.7e-95, (77.95% identity in 349 aa
FT                   overlap). Also highly similar to others e.g.
FT                   Q9ZBS0|GPDA_STRCO from Streptomyces coelicolor (336 aa),
FT                   FASTA scores: opt: 1165, E(): 9.8e-64, (56.25% identity in
FT                   327 aa overlap); P46919|GPDA_BACSU from Bacillus subtilis
FT                   (345 aa), FASTA scores: opt: 872, E(): 7.5e-46, (44.9%
FT                   identity in 325 aa overlap);
FT                   P37606|GPDA_ECOLI|GPSA|B3608|Z5035|ECS4486. from
FT                   Escherichia coli strain O157:H7 and K12 (339 aa), FASTA
FT                   scores: opt: 799, E(): 2.1e-41, (42.9% identity in 331 aa
FT                   overlap); etc. Also highly similar to O53761|GPD2_MYCTU
FT                   PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE from
FT                   Mycobacterium tuberculosis (341 aa), FASTA scores: opt:
FT                   740, E(): 8.4e-38, (40.35% identity in 322 aa overlap).
FT                   BELONGS TO THE NAD-DEPENDENT GLYCEROL-3-PHOSPHATE
FT                   DEHYDROGENASE FAMILY."
FT                   /db_xref="GOA:P59961"
FT                   /db_xref="InterPro:IPR006109"
FT                   /db_xref="UniProtKB/Swiss-Prot:P59961"
FT                   /protein_id="CAD96693.1"
FT                   /translation="MAGIASTVAVMGAGAWGTALAKVLADAGGEVTLWARRAEVADQIN
FT                   TTRYNPDYLPGALLPPSIHATADAEEALGGASTVLLGVPAQTMRANLERWAPLLPEGAT
FT                   LVSLAKGIELGTLMRMSQVIISVTGAEPAQVAVISGPNLASEIAECQPAATVVACSDSG
FT                   RAVALQRALNSGYFRPYTNADVVGTEIGGACKNIIALACGMAVGIGLGENTAAAIITRG
FT                   LAEIIRLGTALGANGATLAGLAGVGDLVATCTSPRSRNRSFGERLGRGETLQSAGKACH
FT                   VVEGVTSCESVLALASSYDVEMPLTDAVHRVCHKGLSVDEAITLLLGRRTKPE"
FT   CDS             170678..171322
FT                   /transl_table=11
FT                   /gene="Mb3007"
FT                   /locus_tag="Mb3007"
FT                   /product="CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN"
FT                   /note="Mb3007, -, len: 214 aa. Equivalent to Rv2983, len:
FT                   214 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 214 aa overlap). Conserved hypothetical
FT                   ala-rich protein, equivalent to O33128|ML1680|MLCB637.37c
FT                   HYPOTHETICAL 22.0 KDA PROTEIN from Mycobacterium leprae
FT                   (216 aa), FASTA scores: opt: 1080, E(): 9e-61, (79.05%
FT                   identity in 215 aa overlap). Also similar to other
FT                   hypothetical proteins e.g. Q9ZBS2|SC7A1.01C from
FT                   Streptomyces coelicolor (212 aa), FASTA scores: opt: 420,
FT                   E(): 2.9e-19, (43.5% identity in 207 aa overlap);
FT                   O26710|MTH613 from Methanothermobacter thermautotrophicus
FT                   (223 aa), FASTA scores: opt: 193, E(): 5.8e-05, (30.0%
FT                   identity in 190 aa overlap); Q9RKG8|SCE46.21 from
FT                   Streptomyces coelicolor (210 aa), FASTA scores: opt: 139,
FT                   E(): 0.14, (27.65% identity in 206 aa overlap); etc."
FT                   /db_xref="InterPro:IPR002835"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH8"
FT                   /protein_id="CAD96694.1"
FT                   /translation="MSGTPDDGDIGLIIAVKRLAAAKTRLAPVFSAQTRENVVLAMLVD
FT                   TLTAAAGVGSLRSITVITPDEAAAAAAAGLGADVLADPTPEDDPDPLNTAITAAERVVA
FT                   EGASNIVVLQGDLPALQTQELAEAISAARHHRRSFVADRLGTGTAVLCAFGTALHPRFG
FT                   PDSSARHRRSGAVELTGAWPGLRCDVDTPADLTAARQLGVGPATARAVAHR"
FT   CDS             171414..173642
FT                   /transl_table=11
FT                   /gene="ppk"
FT                   /locus_tag="Mb3008"
FT                   /product="PROBABLE POLYPHOSPHATE KINASE PPK (POLYPHOSPHORIC
FT                   ACID KINASE) (ATP-POLYPHOSPHATE PHOSPHOTRANSFERASE)"
FT                   /EC_number="2.7.4.1"
FT                   /note="Mb3008, ppk, len: 742 aa. Equivalent to Rv2984, len:
FT                   742 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 742 aa overlap). Probable ppk,
FT                   polyphosphate kinase (EC 2.7.4.1), equivalent to
FT                   O33127|PPK_MYCLE POLYPHOSPHATE KINASE from Mycobacterium
FT                   leprae (739 aa), FASTA scores: opt: 4264, E(): 0, (87.85%
FT                   identity in 742 aa overlap). Also highly similar to others
FT                   e.g. Q9KZV6|PPK_STRCO from Streptomyces coelicolor (746
FT                   aa), FASTA scores: opt: 1979, E(): 2.6e-117, (59.9%
FT                   identity in 701 aa overlap); Q9KD27|PPK_BACHD from Bacillus
FT                   halodurans (705 aa), FASTA scores: opt: 1319, E(): 1.4e-75,
FT                   (45.55% identity in 674 aa overlap); Q9PAC7|PPK_XYLFA from
FT                   Xylella fastidiosa (698 aa), FASTA scores: opt: 1300, E():
FT                   2.2e-74, (43.3% identity in 693 aa overlap); etc. BELONGS
FT                   TO THE POLYPHOSPHATE KINASE FAMILY."
FT                   /db_xref="GOA:P65769"
FT                   /db_xref="InterPro:IPR003414"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65769"
FT                   /protein_id="CAD96695.1"
FT                   /translation="MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAIS
FT                   DQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLK
FT                   RRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWAD
FT                   LDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARV
FT                   KVPDNVDRFVELAAREASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFR
FT                   ITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPG
FT                   DVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVH
FT                   HPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEI
FT                   KARFDEQANIAWARALEQAGVHVAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYN
FT                   SKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVER
FT                   EVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQG
FT                   ISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQ
FT                   LDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQESLMERHRSP"
FT   CDS             173725..174678
FT                   /transl_table=11
FT                   /gene="mutT1"
FT                   /locus_tag="Mb3009"
FT                   /product="POSSIBLE HYDROLASE MUTT1"
FT                   /EC_number="3.-.-.-"
FT                   /note="Mb3009, mutT1, len: 317 aa. Equivalent to Rv2985,
FT                   len: 317 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 317 aa overlap). Possible mutT1, long
FT                   mutt protein (hydrolase) (EC 3.-.-.-), highly similar to
FT                   O33126|MLCB637.35 HYPOTHETICAL 34.5 KDA PROTEIN from
FT                   Mycobacterium leprae (312 aa), FASTA scores: opt: 1514,
FT                   E(): 5.1e-91, (71.85% identity in 316 aa overlap); and
FT                   Q9CBR8|ML1682 HYPOTHETICAL PROTEIN from Mycobacterium
FT                   leprae (311 aa), FASTA scores: opt: 1510, E(): 9.2e-91,
FT                   (71.5% identity in 316 aa overlap). Also similar to
FT                   Q50195|L222-ORF6|ML2698 HYPOTHETICAL PROTEIN from
FT                   Mycobacterium leprae (251 aa), FASTA scores: opt: 231, E():
FT                   1.1e-07, (36.7% identity in 128 aa overlap). Also similar
FT                   to shorter mutt proteins and related hypothetical protein
FT                   e.g. Q9EUS6 HYPOTHETICAL 16.6 KDA PROTEIN from Streptomyces
FT                   griseus subsp. griseus (152 aa), FASTA scores: opt: 380,
FT                   E(): 1.7e-17, (50.75% identity in 130 aa overlap);
FT                   Q9KZV8|SCD84.10C PUTATIVE MUTT-LIKE PROTEIN from
FT                   Streptomyces coelicolor (142 aa), FASTA scores: opt: 376,
FT                   E(): 2.9e-17, (46.1% identity in 128 aa overlap);
FT                   P96590|MUTT MUTT PROTEIN from Bacillus subtilis (149 aa),
FT                   FASTA scores: opt: 180, E(): 0.00017, (35.25% identity in
FT                   122 aa overlap); etc. Also similar to O05437 HYPOTHETICAL
FT                   27.1 KDA PROTEIN from Mycobacterium tuberculosis (248 aa),
FT                   FASTA scores: opt: 224, E(): 3.2e-07, (34.03% identity in
FT                   144 aa overlap). Contains PS00893 mutT domain signature.
FT                   SEEMS TO BELONG TO THE MUTT/NUDIX FAMILY PROTEIN."
FT                   /db_xref="GOA:Q7TXH7"
FT                   /db_xref="InterPro:IPR013078"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH7"
FT                   /protein_id="CAD96696.1"
FT                   /translation="MSIQNSSARRRSAGRIVYAAGAVLWRPGSADSEGPVEIAVIHRPR
FT                   YDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVTYPTDSPFRGVKKVHYW
FT                   AARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQDRKVLCRFAKHPADTQTVLVVRHGT
FT                   AGSKAHFSGDDSKRPLDKRGRAQAEALVPQLLAFGATDVYAADRVRCHQTMEPLAAELN
FT                   VTIHNEPTLTEESYANNPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHP
FT                   DKSRNRKGSTWVLSLSAGRLVTADHIGGALAANVRA"
FT   CDS             complement(174736..175380)
FT                   /transl_table=11
FT                   /gene="hupB"
FT                   /locus_tag="Mb3010c"
FT                   /standard_name="hup; hlp; lbp21"
FT                   /product="PROBABLE DNA-BINDING PROTEIN HU HOMOLOG HUPB
FT                   (HISTONE-LIKE PROTEIN) (HLP) (21-KDA LAMININ-2-BINDING
FT                   PROTEIN)"
FT                   /note="Mb3010c, hupB, len: 214 aa. Equivalent to Rv2986c,
FT                   len: 214 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 214 aa overlap). Probable hupB
FT                   (alternate gene names: hup, hlp, lbp21), DNA-binding
FT                   protein HU homolog (resembles fusion between HU and
FT                   histone) (see first citation below), equivalent to others
FT                   from Mycobacteria e.g. Q9XB18|DBH_MYCBO from Mycobacterium
FT                   bovis (205 aa), FASTA scores: opt: 1050, E(): 5.6e-45,
FT                   (95.35% identity in 214 aa overlap); Q9ZHC5|DBH_MYCSM from
FT                   Mycobacterium smegmatis (208 aa), FASTA scores: opt: 1035,
FT                   E(): 3.1e-44, (80.2% identity in 217 aa overlap); and
FT                   O33125|DBH_MYCLE from Mycobacterium leprae (200 aa), FASTA
FT                   scores: opt: 914, E(): 2.7e-38, (80.1% identity in 216 aa
FT                   overlap). Also highly similar to others from other
FT                   organisms e.g. O86537|DBH2_STRCO from Streptomyces
FT                   coelicolor (218 aa), FASTA scores: opt: 569, E(): 2.6e-21,
FT                   (51.35% identity in 220 aa overlap); P08821|DBH1_BACSU from
FT                   Bacillus subtilis (92 aa), FASTA scores: opt: 280, E():
FT                   2.5e-07, (45.05% identity in 91 aa overlap) (C-terminus
FT                   shorter); etc. Contains PS00045 Bacterial histone-like
FT                   DNA-binding proteins signature. BELONGS TO THE BACTERIAL
FT                   HISTONE-LIKE PROTEIN FAMILY. Note that its C-terminal
FT                   domain is very rich in lysine and alanine."
FT                   /db_xref="GOA:Q9XB18"
FT                   /db_xref="HSSP:1HUU"
FT                   /db_xref="InterPro:IPR000119"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q9XB18"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96697.1"
FT                   /translation="MNKAELIDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTIT
FT                   GFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPAEGPAVKR
FT                   GVGASAAKKVAKKAPAKKATKAAKKAATKAPARKAATKAPAKKAATKAPAKKAVKATKS
FT                   PAKKVTKAVKKTAVKASVRKAATKAPAKKAAAKRPATKAPAKKATARRGRK"
FT   CDS             complement(175593..176189)
FT                   /transl_table=11
FT                   /gene="leuD"
FT                   /locus_tag="Mb3011c"
FT                   /product="PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL
FT                   SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM
FT                   ISOMERASE) (IPMI)"
FT                   /EC_number="4.2.1.33"
FT                   /note="Mb3011c, leuD, len: 198 aa. Equivalent to Rv2987c,
FT                   len: 198 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 198 aa overlap). Probable leuD,
FT                   3-isopropylmalate dehydratase, small subunit (EC 4.2.1.33),
FT                   equivalent to O33124|LEUD_MYCLE 3-ISOPROPYLMALATE
FT                   DEHYDRATASE SMALL SUBUNIT from Mycobacterium leprae (198
FT                   aa), FASTA scores: opt: 1155, E(): 4.2e-72, (87.75%
FT                   identity in 196 aa overlap). Also highly similar to many
FT                   e.g. O86535|LEUD_STRCO from Streptomyces coelicolor (197
FT                   aa), FASTA scores: opt: 765, E(): 2.6e-45, (59.0% identity
FT                   in 195 aa overlap); P04787|LEUD_SALTY from Salmonella
FT                   typhimurium (201 aa), FASTA scores: opt: 528, E(): 5.2e-29,
FT                   (45.05% identity in 191 aa overlap);
FT                   P30126|LEUD_ECOLI|LEUD|B0071 from Escherichia coli strain
FT                   K12 (201 aa), FASTA scores: opt: 498, E(): 6e-27, (43.45%
FT                   identity in 191 aa overlap); etc. TBparse score is 0.939."
FT                   /db_xref="GOA:P65278"
FT                   /db_xref="InterPro:IPR000573"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65278"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96698.1"
FT                   /translation="MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAG
FT                   WRSDPAFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGN
FT                   AGKAGLLAAEVAQDDVELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRL
FT                   LEGLDDIALTLRKLDEIEAFEGACAYWKPRTLPAP"
FT   CDS             complement(176214..177635)
FT                   /transl_table=11
FT                   /gene="leuC"
FT                   /locus_tag="Mb3012c"
FT                   /product="PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (LARGE
FT                   SUBUNIT) LEUC (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM
FT                   ISOMERASE) (IPMI)"
FT                   /EC_number="4.2.1.33"
FT                   /note="Mb3012c, leuC, len: 473 aa. Equivalent to Rv2988c,
FT                   len: 473 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 473 aa overlap). Probable leuC,
FT                   3-isopropylmalate dehydratase, large subunit (EC 4.2.1.33),
FT                   equivalent to O33123|LEU2_MYCLE 3-ISOPROPYLMALATE
FT                   DEHYDRATASE SMALL SUBUNIT from Mycobacterium leprae (476
FT                   aa), FASTA scores: opt: 2818, E(): 1.3e-171, (88.75%
FT                   identity in 471 aa overlap). Also highly similar to many
FT                   e.g. Q44427|LEU2_ACTTI from Actinoplanes teichomyceticus
FT                   (485 aa), FASTA scores: opt: 1958, E(): 6.5e-117, (71.0%
FT                   identity in 479 aa overlap); P55251|LEU2_RHIPU from
FT                   Rhizomucor pusillus (755 aa), FASTA scores: opt: 1937, E():
FT                   1.9e-115, (61.25% identity in 467 aa overlap) (C-terminus
FT                   longer); P30127|LEU2_ECOLI|LEUC|B0072 from Escherichia coli
FT                   strain K12 (465 aa), FASTA scores: opt: 1896, E():
FT                   5.5e-113, (61.6% identity in 456 aa overlap); etc. Contains
FT                   PS00450 Aconitase family signature. BELONGS TO THE
FT                   ACONITASE/IPM ISOMERASE FAMILY. TBparse score is 0.895."
FT                   /db_xref="GOA:Q7TXH6"
FT                   /db_xref="InterPro:IPR015936"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXH6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96699.1"
FT                   /translation="MALQTGEPRTLAEKIWDDHIVVSGGGCAPDLIYIDLHLVHEVTSP
FT                   QAFDGLRLAGRRVRRPELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRL
FT                   HSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQ
FT                   TLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEG
FT                   RMTICNMSIEAGARAGMVAPDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFD
FT                   TEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTA
FT                   MREIAVDAVFVGSCTNGRIEDLRVVAEVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLG
FT                   EIFTDAGAQWRQAGCSMCLGMNPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAA
FT                   ATAVRGTLSSPADLN"
FT   CDS             177707..178408
FT                   /transl_table=11
FT                   /gene="Mb3013"
FT                   /locus_tag="Mb3013"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN"
FT                   /note="Mb3013, -, len: 233 aa. Equivalent to Rv2989, len:
FT                   233 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 233 aa overlap). Probable
FT                   transcriptional regulator (ala-rich protein), highly
FT                   similar to O86533|SC1C2.33c PUTATIVE TRANSCRIPTIONAL
FT                   REGULATOR from Streptomyces coelicolor (238 aa), FASTA
FT                   scores: opt: 711, E(): 2.3e-38, (53.05% identity in 230 aa
FT                   overlap); and similar to others e.g. Q9KND6 PUTATIVE
FT                   TRANSCRIPTIONAL REGULATOR from Vibrio cholerae (244 aa),
FT                   FASTA scores: opt: 232, E(): 1.2e-07, (29.75% identity in
FT                   232 aa overlap); Q9R9U0|SRPS EFFLUX PUMP REGULATOR from
FT                   Pseudomonas putida (259 aa), FASTA scores: opt: 224, E():
FT                   4.1e-07, (28.35% identity in 247 aa overlap); etc. Also
FT                   similar to proteins from Mycobacterium tuberculosis e.g.
FT                   O06806|Rv1773c|MTCY28.39 HYPOTHETICAL 26.6 KDA PROTEIN (248
FT                   aa), FASTA scores: opt: 239, E(): 4.4e-08, (29.85% identity
FT                   in 231 aa overlap); P71977|RV1719|MTCY04C12.04 HYPOTHETICAL
FT                   27.9 KDA PROTEIN (259 aa), FASTA scores: opt: 215, E():
FT                   1.6e-06, (31.85% identity in 223 aa overlap); etc.
FT                   Equivalent to AAK47396 from Mycobacterium tuberculosis
FT                   strain CDC1551 (267 aa) but shorter 34 aa. Contains
FT                   possible helix-turn-helix motif at aa 25-46 (Score 1005,
FT                   +2.61 SD)."
FT                   /db_xref="GOA:Q7TXH5"
FT                   /db_xref="InterPro:IPR005471"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH5"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96700.1"
FT                   /translation="MRQHSGIGVLDKAVGVLHAVAESPCGLAELCDRTDLPRATAYRLA
FT                   AALEVHRLLGRGQDGHWRLGPAITELATHVDDPLLVACAAVLPQLRDATGESVQVYRRE
FT                   GTSRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAHTDAATQAAVLPKAVFSARA
FT                   LAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAAISVSGPIDRMGRRPGVRWAADL
FT                   LSAADALTRRL"
FT   CDS             complement(178419..179279)
FT                   /transl_table=11
FT                   /gene="Mb3014c"
FT                   /locus_tag="Mb3014c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb3014c, -, len: 286 aa. Equivalent to Rv2990c, len:
FT                   286 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 286 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96701.1"
FT                   /translation="MCVTWAEMPKIAALIRHIEDLHARHGRSYILRAGISSLFRYIEGV
FT                   HGERPWGTVLDAGTGVKSLQWIQTLPTERWTAVTAARSLADKTRAALGSAMRPQDRLLV
FT                   GNWVDDSLLAGETFDTILVDYLVGAIEGFAPYWQDRVFERLRPHLADHGRLYLVGLEPY
FT                   VQFEPETESGKIIWEIGRVRDACLLLAGERPYREFPLDWMLGRLGLAGFRILEERRFPI
FT                   RYRARYVNGQLNMCLARIERFSSNGLGMAMRAYVEELRARALQLNERQDGLWHGNDYVI
FT                   AVEPM"
FT   CDS             179542..180033
FT                   /transl_table=11
FT                   /gene="Mb3015"
FT                   /locus_tag="Mb3015"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3015, -, len: 163 aa. Equivalent to Rv2991, len:
FT                   163 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.4% identity in 163 aa overlap). Conserved hypothetical
FT                   protein, similar to others e.g. Q9K3X7|2SCG61.39.
FT                   HYPOTHETICAL 17.6 KDA PROTEIN from Streptomyces coelicolor
FT                   (153 aa), FASTA scores: opt: 266, E(): 2.1e-11, (34.85%
FT                   identity in 155 aa overlap); Q9CNX3|PM0299 HYPOTHETICAL
FT                   PROTEIN from Pasteurella multocida (171 aa), FASTA scores:
FT                   opt: 175, E(): 5.1e-05, (31.3% identity in 131 aa overlap);
FT                   Q9KZI9|SCG8A.10 CONSERVED HYPOTHETICAL PROTEIN from
FT                   Streptomyces coelicolor (142 aa), FASTA scores: opt: 163,
FT                   E(): 0.00031, (32.4% identity in 108 aa overlap); etc. Also
FT                   some similarity to O06553|MTCI65.22|Rv1155 hypothetical
FT                   protein from Mycobacterium tuberculosis (147 aa), FASTA
FT                   scores: opt: 127, E(): 0.1, (32.9% identity in 73 aa
FT                   overlap); and to several proteins of similar size that
FT                   confer resistance to 5-Nitroimidazole antibiotics in
FT                   Bacteroides."
FT                   /db_xref="GOA:Q7TXH3"
FT                   /db_xref="InterPro:IPR011576"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH3"
FT                   /protein_id="CAD96702.1"
FT                   /translation="MGTKQRADIVMSEAEIADFVNSSRTGTLATIGPDGQPHLTAMWYA
FT                   VIDGEIWLETKAKSQKAVNLRRDPRVSFLLEDGDTYDTLRGVSFEGVTEIVEEPEALHR
FT                   VGVSVWERYTGPYTDECKPMVDQMMNKRVGVRIVARRTRSWDHRKLGLPHMSVGGSTAP
FT                   "
FT   tRNA            complement(180107..180179)
FT                   /gene="gluU"
FT                   /locus_tag="gluU"
FT                   /note="gluU, len: 73 nt. Equivalent to gluU, len: 73 nt,
FT                   from Mycobacterrium tuberculosis strain H37Rv, (100.0%
FT                   identity in 73 nt overlap). tRNA-Glu; anticodon ctc."
FT   tRNA            complement(180219..180290)
FT                   /gene="glnU"
FT                   /locus_tag="glnU"
FT                   /note="glnU, len: 72 nt. Equivalent to glnU, len: 72 nt,
FT                   from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 72 nt overlap). tRNA-Gln; anticodon ctg."
FT   CDS             complement(180365..181837)
FT                   /transl_table=11
FT                   /gene="gltS"
FT                   /locus_tag="Mb3016c"
FT                   /standard_name="gltX"
FT                   /product="PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS
FT                   (GLUTAMATE--TRNA LIGASE) (GLUTAMYL-TRNA SYNTHASE) (GLURS)"
FT                   /EC_number="6.1.1.17"
FT                   /note="Mb3016c, gltS, len: 490 aa. Equivalent to Rv2992c,
FT                   len: 490 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 490 aa overlap). Probable gltS
FT                   (alternate gene name: gltX), glutamyl-tRNA synthase (EC
FT                   6.1.1.17), equivalent to O33120|SYE_MYCLE GLUTAMYL-TRNA
FT                   SYNTHETASE from Mycobacterium leprae (502 aa), FASTA
FT                   scores: opt: 2660, E(): 2.3e-163, (81.35% identity in 488
FT                   aa overlap). Also highly similar to others e.g.
FT                   O86528|SYE_STRCO from Streptomyces coelicolor (494 aa),
FT                   FASTA scores: opt: 1777, E(): 1.4e-106, (57.45% identity in
FT                   484 aa overlap); P22250|SYE_BACSU from Bacillus subtilis
FT                   (483 aa), FASTA scores: opt: 1099, E(): 5.4e-63, (38.45%
FT                   identity in 489 aa overlap); O51345|SYE_BORBU|GLTX|BB0372
FT                   from Borrelia burgdorferi (Lyme disease spirochete) (490
FT                   aa), FASTA scores: opt: 1009, E(): 3.3e-57, (34.85%
FT                   identity in 491 aa overlap); etc. BELONGS TO CLASS-I
FT                   AMINOACYL-TRNA SYNTHETASE FAMILY. TBparse score is 0.891."
FT                   /db_xref="GOA:P0A637"
FT                   /db_xref="HSSP:1J09"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A637"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96703.1"
FT                   /translation="MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRI
FT                   EDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLARLLAA
FT                   GEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRMPDD
FT                   DLAWNDLVRGPVTFAAGSVPDFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPST
FT                   PRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLL
FT                   NYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDF
FT                   TVRLRDHLDTHGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFNDDQYVIDPKAAA
FT                   KELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIEGLALKPRKAFSPIRVAATGT
FT                   TVSPPLFESLELLGRDRSMQRLRAARQLVGHA"
FT   CDS             complement(181834..182553)
FT                   /transl_table=11
FT                   /gene="Mb3017c"
FT                   /locus_tag="Mb3017c"
FT                   /product="POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE
FT                   ISOMERASE (HHDD ISOMERASE)"
FT                   /EC_number="5.3.3.-"
FT                   /note="Mb3017c, -, len: 239 aa. Equivalent to Rv2993c, len:
FT                   239 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 239 aa overlap). Possible
FT                   2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-),
FT                   equivalent to O33119|ML1689|MLCB637.28 POSSIBLE
FT                   2-HYDROXYHEPTA-2,4-DIENE- 1,7-DIOATE ISOMERASE from
FT                   Mycobacterium leprae (242 aa), FASTA scores: opt: 1427,
FT                   E(): 4.4e-86, (85.9% identity in 241 aa overlap). Also
FT                   similar to others e.g. Q9LBE3|DR1609 from Deinococcus
FT                   radiodurans (250 aa), FASTA scores: opt: 723, E(): 5.5e-40,
FT                   (49.05% identity in 216 aa overlap); O27551|MTH1507 from
FT                   Methanothermobacter thermautotrophicus (260 aa), FASTA
FT                   scores: opt: 708, E(): 5.4e-39, (52.1% identity in 213 aa
FT                   overlap); Q9HQR6|VNG1037G|HPCE from Halobacterium sp.
FT                   (strain NRC-1) (244 aa), FASTA scores: opt: 590, E():
FT                   2.7e-31, (43.65% identity in 220 aa overlap); etc. Start
FT                   chosen by homology, but ORF could continue upstream.
FT                   TBparse score is 0.896."
FT                   /db_xref="GOA:Q7TXH2"
FT                   /db_xref="HSSP:1GTT"
FT                   /db_xref="InterPro:IPR002529"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH2"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96704.1"
FT                   /translation="MTAREIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYA
FT                   DHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIVIGRACKDVPA
FT                   AQAVDNILGYTIGNDVSARDQQQSDGQWTRAKGHDTFCPVGPWIVTDLAPFDPADLELR
FT                   TVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGPIEDGDTVSIT
FT                   IEGIGTLTNPVVRKGKP"
FT   CDS             182885..184222
FT                   /transl_table=11
FT                   /gene="Mb3018"
FT                   /locus_tag="Mb3018"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN"
FT                   /note="Mb3018, -, len: 445 aa. Equivalent to Rv2994, len:
FT                   445 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 445 aa overlap). Probable conserved
FT                   integral membrane protein, member of major facilitator
FT                   superfamily (MFS) possibly involved in transport of drug.
FT                   C-terminal part highly similar to O33118|MLCB637.27c
FT                   HYPOTHETICAL 14.7 KDA PROTEIN (probable pseudogene product)
FT                   from Mycobacterium leprae (134 aa), FASTA scores: opt: 483,
FT                   E(): 2.7e-21, (60.9% identity in 138 aa overlap). Also
FT                   similar to various transporters e.g. Q9I5C8|PA0811 PROBABLE
FT                   MFS TRANSPORTER from Pseudomonas aeruginosa (415 aa), FASTA
FT                   scores: opt: 289, E(): 1.3e-09, (26.05% identity in 399 aa
FT                   overlap); O30210|AF0025 CYANATE TRANSPORT PROTEIN from
FT                   Archaeoglobus fulgidus (393 aa), FASTA scores: opt: 281,
FT                   E(): 3.7e-09, (24.05% identity in 399 aa overlap);
FT                   Q9RI35|SCJ12.25C PUTATIVE NITRATE/NITRITE TRANSPORTER from
FT                   Streptomyces coelicolor (412 aa), FASTA scores: opt: 264,
FT                   E(): 3.8e-08, (24.95% identity in 409 aa overlap);
FT                   Q9A5N5|CC2412 MAJOR FACILITATOR FAMILY TRANSPORTER from
FT                   Caulobacter crescentus (405 aa), FASTA scores: opt: 263,
FT                   E(): 4.3e-08, (27.55% identity in 399 aa overlap); etc.
FT                   First start taken; similarity to P21191|NORA_STAAU
FT                   QUINOLONE RESISTANCE PROTEIN from Staphylococcus aureus
FT                   (388 aa) suggests alternative start at 7319 but then no
FT                   positively charged aa before first transmembrane segment."
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TVB6"
FT                   /protein_id="CAD96705.1"
FT                   /translation="MSRDPTGVGARWAIMIVSLGVTASSFLFINGVAFLIPRLENARGT
FT                   PLSHAGLLASMPSWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWI
FT                   GVFLFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAER
FT                   GVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWRIHAASAL
FT                   LMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGALGRVAVGRWSDHVGSRMRPV
FT                   RLIAAAAAATLFLLAAVDNEGSRYDVLLMIAISVIAVLDNGLEATAITEYAGPYWSGRA
FT                   LGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRA
FT                   RRQSVRRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT"
FT   CDS             complement(184074..185084)
FT                   /transl_table=11
FT                   /gene="leuB"
FT                   /locus_tag="Mb3019c"
FT                   /product="3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM
FT                   DEHYDROGENASE) (IMDH) (3-IPM-DH)"
FT                   /EC_number="1.1.1.85"
FT                   /note="Mb3019c, leuB, len: 336 aa. Equivalent to Rv2995c,
FT                   len: 336 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 336 aa overlap). leuB, 3-isopropylmalate
FT                   dehydrogenase (EC 1.1.1.85) (see citation below), identical
FT                   except one bp to P94929|LEU3_MYCBO 3-ISOPROPYLMALATE
FT                   DEHYDROGENASE from Mycobacterium bovis (336 aa), FASTA
FT                   scores: opt: 2168, E(): 5.1e-132, (99.7% identity in 336 aa
FT                   overlap); and equivalent to O33117|LEU3_MYCLE
FT                   3-ISOPROPYLMALATE DEHYDROGENASE from Mycobacterium leprae
FT                   (336 aa), FASTA scores: opt: 1864, E(): 1.8e-112, (83.95%
FT                   identity in 336 aa overlap). Also highly similar to others
FT                   e.g. P94631|LEU3_CORGL from Corynebacterium glutamicum (340
FT                   aa), FASTA scores: opt: 1526, E(): 1e-90, (69.9% identity
FT                   in 339 aa overlap); O86504 from Streptomyces coelicolor
FT                   (347 aa), FASTA scores: opt: 1470, E(): 4.2e-87, (67.85%
FT                   identity in 339 aa overlap); Q9UZ05|PAB2424 from Pyrococcus
FT                   abyssi (354 aa), FASTA scores: opt: 998, E(): 1e-56, (50.0%
FT                   identity in 322 aa overlap); etc. Note that also shows high
FT                   similarity with many tartrate dehydrogenases (EC 1.1.1.93).
FT                   BELONGS TO THE ISOCITRATE AND ISOPROPYLMALATE
FT                   DEHYDROGENASES FAMILY."
FT                   /db_xref="GOA:P94929"
FT                   /db_xref="HSSP:1XAA"
FT                   /db_xref="InterPro:IPR001804"
FT                   /db_xref="UniProtKB/Swiss-Prot:P94929"
FT                   /protein_id="CAD96706.1"
FT                   /translation="MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHAT
FT                   GEVLPDSVVAELRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPG
FT                   VASPLSGNPGIDFVVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAF
FT                   ERARRRRKHLTLVHKTNVLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPG
FT                   RFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGI
FT                   ADPTAAIMSVALLLSHLGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL"
FT   CDS             complement(185099..186685)
FT                   /transl_table=11
FT                   /gene="serA1"
FT                   /locus_tag="Mb3020c"
FT                   /standard_name="serA"
FT                   /product="PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1
FT                   (PGDH)"
FT                   /EC_number="1.1.1.95"
FT                   /note="Mb3020c, serA1, len: 528 aa. Equivalent to Rv2996c,
FT                   len: 528 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 528 aa overlap). Probable serA1,
FT                   D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95),
FT                   equivalent to SERA_MYCLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE
FT                   from Mycobacterium leprae (528 aa), FASTA scores: opt:
FT                   2974, E(): 1.9e-166, (89.6% identity in 528 aa overlap).
FT                   Also highly similar to many e.g. Q9Z564 from Streptomyces
FT                   coelicolor (529 aa), FASTA scores: opt: 1879, E():
FT                   2.1e-102, (57.6% identity in 526 aa overlap);
FT                   O29445|SERA_ARCFU from Archaeoglobus fulgidus (527 aa),
FT                   FASTA scores: opt: 1252, E(): 9.6e-66, (41.3% identity in
FT                   530 aa overlap); P35136|SERA_BACSU from Bacillus subtilis
FT                   (525 aa), FASTA scores: opt: 1172, E(): 4.5e-61, (37.9%
FT                   identity in 528 aa overlap); etc. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop), PS00065 D-isomer
FT                   specific 2-hydroxyacid dehydrogenases NAD-binding
FT                   signature, and PS00670 D-isomer specific 2-hydroxyacid
FT                   dehydrogenases signature 2. BELONGS TO THE D-ISOMER
FT                   SPECIFIC 2-HYDROXYACID DEHYDROGENASES FAMILY. Note that
FT                   previously known as serA."
FT                   /db_xref="GOA:P0A545"
FT                   /db_xref="HSSP:1MX3"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A545"
FT                   /protein_id="CAD96707.1"
FT                   /translation="MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEAD
FT                   ALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAE
FT                   HALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAF
FT                   GAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTK
FT                   PGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLG
FT                   ASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVL
FT                   SDELPVSLSVQVRGELAAEEVEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEI
FT                   CKASESPNHRSVVDVRAVGADGSVVTVSGTLYGPQLSQKIVQINGRHFDLRAQGINLII
FT                   HYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAV
FT                   DAYKLEVVDLS"
FT   CDS             186715..188157
FT                   /transl_table=11
FT                   /gene="Mb3021"
FT                   /locus_tag="Mb3021"
FT                   /product="POSSIBLE ALANINE RICH DEHYDROGENASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb3021, -, len: 480 aa. Equivalent to Rv2997, len:
FT                   480 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 480 aa overlap). Possible ala-rich
FT                   dehydrogenase (EC 1.-.-.-), similar to others
FT                   dehydrogenases and hypothetical proteins e.g. Q9EYI5
FT                   PUTATIVE DEHYDROGENASE from Streptomyces nogalater (472
FT                   aa), FASTA scores: opt: 1131, E(): 1.7e-61, (41.0% identity
FT                   in 471 aa overlap); Q9ZBG4|SC9B5.16 PUTATIVE DEHYDROGENASE
FT                   from Streptomyces coelicolor (472 aa), FASTA scores: opt:
FT                   1064, E(): 2e-57, (39.05% identity in 471 aa overlap);
FT                   Q98BS8 PROBABLE DEHYDROGENASE from Rhizobium loti
FT                   (Mesorhizobium loti) (524 aa), FASTA scores: opt: 196, E():
FT                   0.00021, (25.1% identity in 526 aa overlap); etc. Shows
FT                   strong simlarity throughout its length to
FT                   O06826|MTCY493.22c|Rv1432 HYPOTHETICAL 50.5 KDA PROTEIN
FT                   from Mycobacterium tuberculosis (473 aa), FASTA scores:
FT                   opt: 1220, E(): 6.1e-67, (42.35% identity in 465 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7TXH1"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH1"
FT                   /protein_id="CAD96708.1"
FT                   /translation="MDVTVVGSGPNGLATAVICARAGLNVQVVEAQATFGGGARSAADF
FT                   EFPEVLHDVCSAVHPLALASPFFAEFDLPARGVTLTVPDIAYANPLPGRPAAIAYHDLA
FT                   HTSAKLDDGASWRRLLGPLVAHSETVVEFMLSDKRSLPTALGSVLRLGLRMLAQGTPAW
FT                   RSLAGEDARALFTGVAAHAISPLPSLVSAGAGLMLATLAHSVGWPIPVGGTQAIADALI
FT                   ADLRAHGGRLAAGVEITEPQRSVVVFDTAPTALLRVYRDKLPHRYAKALRRYRFRAGIA
FT                   KVDFVLSDEIPWSDPRLRRAATLHLGGTRDQMARAEADVAAGRHADWPMVLAACPHVAD
FT                   PGRIDETGRRPFWTYAHVPSGSTLDATETVTSVLERFAPGFRDIVVAARAVPAARMADH
FT                   NANYVGGDITVGANSTWRAIAGPTPRLNPWRTPIPKVYLCSAATPPGAGVHGMCGWYAA
FT                   RTLLRTEFGITRMPPLGHELRP"
FT   CDS             188430..188891
FT                   /transl_table=11
FT                   /gene="Mb3022"
FT                   /locus_tag="Mb3022"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb3022, -, len: 153 aa. Equivalent to Rv2998, len:
FT                   153 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 153 aa overlap). Hypothetical unknown
FT                   protein. Note that equivalent to AAK47405 Hypothetical 19.4
FT                   kDa protein from Mycobacterium tuberculosis strain CDC1551
FT                   (186 aa) but sequence differs in N-terminus."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXH0"
FT                   /protein_id="CAD96709.1"
FT                   /translation="MDVIWSATIATTVATGMRKPRMHGMPPITSGSMVTRVTRMSIRLA
FT                   GDSTLGRFSTSRLGLSSAKSKPEGDFGTACGAVSGGDAGVVALAEGVDDGQSKPGAAGG
FT                   ARGVGGFRESRADCGEQFGVASWTPQGEFEFGGQEAKGVRSSWPASLTN"
FT   CDS             complement(188840..189043)
FT                   /transl_table=11
FT                   /gene="Mb3023c"
FT                   /locus_tag="Mb3023c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3023c, -, len: 67 aa. Equivalent to Rv2998A, len:
FT                   67 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 67 aa overlap). Probable conserved
FT                   hypothetical protein, (possibly gene fragment), highly
FT                   similar to central part of two-component sensor proteins
FT                   e.g. O07777|Rv0601c|MTCY19H5.21 TWO COMPONENT SENSOR
FT                   (FRAGMENT) from Mycobacterium tuberculosis (156 aa), FASTA
FT                   scores: opt: 212, E(): 3.7e-09, (58.2% identity in 67 aa
FT                   overlap); Q9L2B6|SC8F4.08 PROBABLE TWO-COMPONENT SENSOR
FT                   KINASE from Streptomyces coelicolor (478 aa), FASTA scores:
FT                   opt: 193, E(): 2.6e-07, (47.05% identity in 68 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:Q7TXG9"
FT                   /db_xref="InterPro:IPR003660"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG9"
FT                   /protein_id="CAD96710.1"
FT                   /translation="MERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQD
FT                   ALERERQFVSDAGHELRTPLAS"
FT   CDS             189217..190182
FT                   /transl_table=11
FT                   /gene="lppY"
FT                   /locus_tag="Mb3024"
FT                   /product="PROBABLE CONSERVED LIPOPROTEIN LPPY"
FT                   /note="Mb3024, lppY, len: 321 aa. Equivalent to Rv2999,
FT                   len: 321 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 321 aa overlap). Probable lppY,
FT                   conserved lipoprotein, highly similar to
FT                   O07774|LPQO|Rv0604|MTCY19H5.18c PUTATIVE LIPOPROTEIN from
FT                   Mycobacterium tuberculosis (316 aa), FASTA scores: opt:
FT                   1153, E(): 5e-62, (53.2% identity in 312 aa overlap); and
FT                   showing similarity with AAK80743|CAC2799 UNCHARACTERIZED
FT                   CONSERVED PROTEIN SIMILAR TO LPPY/LPQO OF Mycobacterium
FT                   tuberculosis from Clostridium acetobutylicum (152 aa),
FT                   FASTA scores: opt: 165, E(): 0.0077, (26.08% identity in
FT                   138 aa overlap); and Q9F2T1|SCD65.01c PUTATIVE LIPOPROTEIN
FT                   (FRAGMENT) from Streptomyces coelicolor (146 aa), FASTA
FT                   scores: opt: 126, E(): 1.6, (% identity in aa overlap).
FT                   Equivalent to AAK47407 from Mycobacterium tuberculosis
FT                   strain CDC1551 (329 aa) but shorter 8 aa. Contains probable
FT                   N-terminal signal sequence and PS00013 Prokaryotic membrane
FT                   lipoprotein lipid attachment site."
FT                   /db_xref="InterPro:IPR011094"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG8"
FT                   /protein_id="CAD96711.1"
FT                   /translation="MAGAKHAGRIVAITTAAAVILAACSSGSKGGAGSGHAGKARSAVT
FT                   TTDADWKPVADALGRSGKLGDNNTAYRINLPRNDLHITSYGVDIKPGLSLGGYAAFARY
FT                   DNNETLLMGDLVITEEELPKVTDALQAHGIAQTALHKHLLQQDPPVWWTHIHGMGDAAR
FT                   LAQGLKAALDATTIGPPTPPPARQPPVDIDVAGVDQALGRKGTQDGGLLKYSIPRKDTI
FT                   IEDGHVLPAVSLNLTTVINFQPVGRGRAAINGDFILIAPEVQEVIRAMRAGNITIVELH
FT                   NHGLTEEPRLFYMHYWAVDDAVTLARALRPAMDATNLQSS"
FT   CDS             190227..190886
FT                   /transl_table=11
FT                   /gene="Mb3025"
FT                   /locus_tag="Mb3025"
FT                   /product="POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb3025, -, len: 219 aa. Equivalent to Rv3000, len:
FT                   219 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 219 aa overlap). Possible conserved
FT                   transmembrane protein, similar to various membrane proteins
FT                   e.g. P77307|YBBM_ECOLI|B0491 HYPOTHETICAL 28.2 KDA PROTEIN
FT                   (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from Escherichia coli
FT                   strain K12 (259 aa), FASTA scores: opt: 292, E(): 3.1e-11,
FT                   (30.25% identity in 218 aa overlap); N-terminus of Q9BJF3
FT                   PUTATIVE ABC TRANSPORTER (FRAGMENT) from Sterkiella
FT                   histriomuscorum (1319 aa), FASTA scores: opt: 274, E():
FT                   1.3e-09, (39.6% identity in 101 aa overlap);
FT                   Q9C9W0|T23K23.21 PUTATIVE ABC TRANSPORTER from Arabidopsis
FT                   thaliana (Mouse-ear cress) (263 aa), FASTA scores: opt:
FT                   258, E(): 4.4e-09, (30.1% identity in 196 aa overlap);
FT                   P74369|YG47_SYNY3|SLR1647 HYPOTHETICAL 28.1 KDA PROTEIN
FT                   (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from Synechocystis
FT                   sp. strain PCC 6803 (259 aa), FASTA scores: opt: 257, E():
FT                   5.1e-09, (37.75% identity in 98 aa overlap); etc. Contains
FT                   PS00017 ATP/GTP-binding site motif A (P-loop)."
FT                   /db_xref="GOA:Q7TXG7"
FT                   /db_xref="InterPro:IPR003439"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG7"
FT                   /protein_id="CAD96712.1"
FT                   /translation="MAVHGFLLERVSVVRDEATVLRQVSAHFPAGRCSAVRGASGSGKT
FT                   TLLRLLNRLIDPTSGKVWLDGVPLTDLDVLVLRRRVGLVAQAPVVLTDAVLNEVRVGRP
FT                   DLPEGRVTELLARLCLGQSAREAFLPHQRSALRTALIPAIDSTKVVGLISLPGAMSGLI
FT                   LAGVDPLTAIRYQIVVMYLLLAATAVAALTCARLAERALFDRAHRLVSLPAATRRA"
FT   CDS             complement(191200..192201)
FT                   /transl_table=11
FT                   /gene="ilvC"
FT                   /locus_tag="Mb3026c"
FT                   /product="PROBABLE KETOL-ACID REDUCTOISOMERASE ILVC
FT                   (Acetohydroxy-acid isomeroreductase)
FT                   (Alpha-keto-beta-hydroxylacil reductoisomerase)"
FT                   /EC_number="1.1.1.86"
FT                   /note="Mb3026c, ilvC, len: 333 aa. Equivalent to Rv3001c,
FT                   len: 333 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 333 aa overlap). Probable ilvC,
FT                   ketol-acid reductoisomerase (EC 1.1.1.86), equivalent or
FT                   highly similar to others e.g. Q59500|ILVC_MYCAV from
FT                   Mycobacterium avium (333 aa), FASTA scores: opt: 1977, E():
FT                   3.2e-113, (87.7% identity in 333 aa overlap);
FT                   O33114|ILVC_MYCLE from Mycobacterium leprae (333 aa), FASTA
FT                   scores: opt: 1924, E(): 5.3e-110, (86.5% identity in 333 aa
FT                   overlap); Q9Z565|ILVC_STRCO|SC8D9.26 from Streptomyces
FT                   coelicolor (332 aa), FASTA scores: opt: 1494, E(): 8.3e-84,
FT                   (67.5% identity in 326 aa overlap); Q59818|ILVC_STRAW from
FT                   Streptomyces avermitilis (333 aa) FASTA scores: opt: 1487,
FT                   E(): 2.2e-83, (66.8% identity in 326 aa overlap); etc.
FT                   BELONGS TO THE KETOL-ACID REDUCTOISOMERASES FAMILY."
FT                   /db_xref="GOA:P65150"
FT                   /db_xref="HSSP:1NP3"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65150"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96713.1"
FT                   /translation="MFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLK
FT                   QGSRSRPKVEEQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFG
FT                   HGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGKGVPCLVAVEQDPRGDGLALAL
FT                   SYAKAIGGTRAGVIKTTFKDETETDLFGEQTVLCGGTEELVKAGFEVMVEAGYPAELAY
FT                   FEVLHELKLIVDLMYEGGLARMYYSVSDTAEFGGYLSGPRVIDAGTKERMRDILREIQD
FT                   GSFVHKLVADVEGGNKQLEELRRQNAEHPIEVVGKKLRDLMSWVDRPITETA"
FT   CDS             complement(192239..192745)
FT                   /transl_table=11
FT                   /gene="ilvN"
FT                   /locus_tag="Mb3027c"
FT                   /standard_name="ilvH"
FT                   /product="PROBABLE ACETOLACTATE SYNTHASE (SMALL SUBUNIT)
FT                   ILVN (ACETOHYDROXY-ACID SYNTHASE) (AHAS) (ALS)"
FT                   /EC_number="2.2.1.6"
FT                   /note="Mb3027c, ilvN, len: 168 aa. Equivalent to Rv3002c,
FT                   len: 168 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 168 aa overlap). Probable ilvN
FT                   (alternate gene name: ilvH), acetolactate synthase, small
FT                   subunit (EC 4.1.3.18), equivalent or highly similar to
FT                   others e.g. O33113|ILVH_MYCLE|MLCB637.21 from Mycobacterium
FT                   leprae (169 aa), FASTA scores: opt: 843, E(): 5.1e-47,
FT                   (83.5% identity in 164 aa overlap); Q59499|ILVH_MYCAV|ILVN
FT                   from Mycobacterium avium (167 aa), FASTA scores: opt: 798,
FT                   E(): 3.7e-44, (81.05% identity in 169 aa overlap);
FT                   Q9Z566|ILVN from Streptomyces coelicolor (174 aa), FASTA
FT                   scores: opt: 678, E(): 1.7e-36, (64.8% identity in 159 aa
FT                   overlap); etc. BELONGS TO THE ACETOLACTATE SYNTHASE SMALL
FT                   SUBUNIT FAMILY."
FT                   /db_xref="GOA:P65162"
FT                   /db_xref="InterPro:IPR002912"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65162"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96714.1"
FT                   /translation="MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKD
FT                   RSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQV
FT                   IEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRG
FT                   IGTAK"
FT   CDS             complement(192745..194601)
FT                   /transl_table=11
FT                   /gene="ilvB1"
FT                   /locus_tag="Mb3028c"
FT                   /standard_name="ilvB"
FT                   /product="PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT)
FT                   ILVB1 (ACETOHYDROXY-ACID SYNTHASE)"
FT                   /EC_number="2.2.1.6"
FT                   /note="Mb3028c, ilvB1, len: 618 aa. Equivalent to Rv3003c,
FT                   len: 618 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 618 aa overlap). Probable ilvB1,
FT                   acetolactate synthase, large subunit (EC 4.1.3.18),
FT                   equivalent or highly similar to others e.g.
FT                   O33112|ILVB_MYCLE|MLCB637.20|ML1696 from Mycobacterium
FT                   leprae (625 aa), FASTA scores: opt: 3653, E(): 5.4e-208,
FT                   (87.1% identity in 627 aa overlap); Q59498|ILVB_MYCAV from
FT                   Mycobacterium avium (621 aa), FASTA scores: opt: 3473, E():
FT                   2.3e-197, (84.7% identity in 614 aa overlap);
FT                   P42463|ILVB_CORGL from Corynebacterium glutamicum
FT                   (Brevibacterium flavum) (626 aa), FASTA scores: opt: 2754,
FT                   E(): 5.9e-155, (65.8% identity in 589 aa overlap); etc.
FT                   Contains PS00187 Thiamine pyrophosphate enzymes signature.
FT                   COFACTOR: THIAMINE PYROPHOSPHATE, AND MAGNESIUM (BY
FT                   SIMILARITY). Note that previously known as ilvB."
FT                   /db_xref="GOA:P0A623"
FT                   /db_xref="HSSP:1N0H"
FT                   /db_xref="InterPro:IPR012000"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A623"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96715.1"
FT                   /translation="MSAPTKPHSPTFKPEPHSAANEPKHPAARPKHVALQQLTGAQAVI
FT                   RSLEELGVDVIFGIPGGAVLPVYDPLFDSKKLRHVLVRHEQGAGHAASGYAHVTGRVGV
FT                   CMATSGPGATNLVTPLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKHN
FT                   FLVRSGDDIPRVLAEAFHIAASGRPGAVLVDIPKDVLQGQCTFSWPPRMELPGYKPNTK
FT                   PHSRQVREAAKLIAAARKPVLYVGGGVIRGEATEQLRELAELTGIPVVTTLMARGAFPD
FT                   SHRQNLGMPGMHGTVAAVAALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPA
FT                   EIGKNRHADVPIVGDVKAVITELIAMLRHHHIPGTIEMADWWAYLNGVRKTYPLSYGPQ
FT                   SDGSLSPEYVIEKLGEIAGPDAVFVAGVGQHQMWAAQFIRYEKPRSWLNSGGLGTMGFA
FT                   IPAAMGAKIALPGTEVWAIDGDGCFQMTNQELATCAVEGIPVKVALINNGNLGMVRQWQ
FT                   SLFYAERYSQTDLATHSHRIPDFVKLAEALGCVGLRCEREEDVVDVINQARAINDCPVV
FT                   IDFIVGADAQVWPMVAAGTSNDEIQAARGIRPLFDDITEGHA"
FT   CDS             194963..195301
FT                   /transl_table=11
FT                   /gene="cfp6"
FT                   /locus_tag="Mb3029"
FT                   /product="LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 6 (CFP-6)"
FT                   /note="Mb3029, cfp6, len: 112 aa. Equivalent to Rv3004,
FT                   len: 112 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 112 aa overlap). cfp6, low molecular
FT                   weight protein antigen 6 (CFP-6) (cf note * below). Weak
FT                   homology with Q9RKZ5|SC6D7.02 PUTATIVE MEMBRANE PROTEIN
FT                   from Streptomyces coelicolor (156 aa), FASTA scores: opt:
FT                   109, E(): 0.78, (39.4% identity in 122 aa overlap).
FT                   CAUTION: THE INITIATOR METHIONINE MAY BE FURTHER UPSTREAM
FT                   MAKING THE SEQUENCE A PRECURSOR. [* Note: Bhaskar S.,
FT                   Mukherjee R.: Isolation, purification and immunological
FT                   characterization of low molecular weight protein antigens
FT                   from culture filtrate of Mycobacterium tuberculosis H37Rv.
FT                   Unpublished. Submitted (NOV-1998) to the SWISS-PROT data
FT                   bank]."
FT                   /db_xref="GOA:P0A5P3"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5P3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96716.1"
FT                   /translation="MAHFAVGFLTLGLLVPVLTWPVSAPLLVIPVALSASIIRLRTLAD
FT                   ERGVTVRTLVGSRAVRWDDIDGLRFHRGSWARATLKDGTELRLPAVTFATLPHLTEASS
FT                   GRVPNPYR"
FT   CDS             complement(195308..196147)
FT                   /transl_table=11
FT                   /gene="Mb3030c"
FT                   /locus_tag="Mb3030c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3030c, -, len: 279 aa. Equivalent to Rv3005c, len:
FT                   279 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 279 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O33110|MLCB637.18|ML1698
FT                   HYPOTHETICAL 29.5 KDA PROTEIN from Mycobacterium leprae
FT                   (277 aa), FASTA scores: opt: 1245, E(): 1.2e-65, (70.5%
FT                   identity in 278 aa overlap). Also similar, but longer 100
FT                   aa in N-terminus, to other hypothetical proteins, few
FT                   membrane proteins, e.g. Q9RKN9|SCC75A.35 PUTATIVE MEMBRANE
FT                   PROTEIN from Streptomyces coelicolor (180 aa), FASTA
FT                   scores: opt: 326, E(): 3.9e-12, (44.2% identity in 138 aa
FT                   overlap); P96694|YDFP|AB001488 HYPOTHETICAL PROTEIN from
FT                   Bacillus subtilis (129 aa), FASTA scores: opt:273, E():
FT                   3.7e-09, (33.1% identity in 130 aa overlap); Q9KKT1|VCA1019
FT                   HYPOTHETICAL PROTEIN from Vibrio cholerae (148 aa), FASTA
FT                   scores: opt: 258, E(): 3.1e-08, (34.9% identity in 126 aa
FT                   overlap); etc."
FT                   /db_xref="InterPro:IPR011637"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG6"
FT                   /protein_id="CAD96717.1"
FT                   /translation="MTSSNDSHWQRPDDSPGPMPGRPVSASLVDPEDDLTPARYAGDFG
FT                   SGTTTVIPPYDAASSGVGNSGYSLIEAAEPLPYVQPQPGRQVPAGSAGIDMDDDERVRA
FT                   AGRRGTQNLGLLILRVGLGAVLIAHGLQKLFGWWDGQGLAGFQNSLSDIGYQHAEILAY
FT                   VSAGGEIVAGVLLVLGLFTPLAAAGALAFLINGLLAGISAQHSRPVAYFLQDGHEYQIT
FT                   LVVMAVAVILSGPGRYGLDAARGWAHRPFIGSFVALLGGIAAGIAVWVLLNGANPLA"
FT   CDS             196324..197445
FT                   /transl_table=11
FT                   /gene="lppZ"
FT                   /locus_tag="Mb3031"
FT                   /product="PROBABLE CONSERVED LIPOPROTEIN LPPZ"
FT                   /note="Mb3031, lppZ, len: 373 aa. Equivalent to Rv3006,
FT                   len: 373 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 373 aa overlap). Probable lppZ,
FT                   conserved lipoprotein, equivalent to
FT                   O33109|MLCB637.17C|ML1699 putative lipoprotein from M.
FT                   leprae (372 aa), FASTA scores: opt: 2211, E(): 4.3e-100,
FT                   (87.1% identity in 373 aa overlap). Shows also similarity
FT                   (in part) with Q9Z571|SC8D9.20c PUTATIVE OXIDOREDUCTASE
FT                   from Streptomyces coelicolor (447 aa), FASTA scores: opt:
FT                   185, E(): 0.051, (31.6% identity in 300 aa overlap);
FT                   Q9Z9R3|BH2090 GLUCOSE DEHYDROGENASE-B from Bacillus
FT                   halodurans (371 aa), FASTA scores: opt: 206, E(): 0.0043,
FT                   (28.3% identity in 205 aa overlap); and other GLUCOSE
FT                   DEHYDROGENASES B. Contains signal sequence and
FT                   appropriately positioned PS00013 Prokaryotic membrane
FT                   lipoprotein lipid attachment site, followed by a
FT                   proline-rich domain."
FT                   /db_xref="GOA:Q7TXG5"
FT                   /db_xref="InterPro:IPR011042"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG5"
FT                   /protein_id="CAD96718.1"
FT                   /translation="MWTTRLVRSGLAALCAAVLVSSGCARFNDAQSQPFTTEPELRPQP
FT                   SSTPPPPPPLPPVPFPKECPAPGVMQGCLESTSGLIMGIDSKTALVAERITGAVEEISI
FT                   SAEPKVKTVIPVDPAGDGGLMDIVLSPTYSQDRLMYAYISTPTDNRVVRVADGDIPKDI
FT                   LTGIPKGAAGNTGALIFTSPTTLVVMTGDAGDPALAADPQSLAGKVLRIEQPTTIDQTP
FT                   PTTALSGIGSGGGLCIDPVDGSLYVADRTPTADRLQRITKNSEVSTVWTWPDKPGVAGC
FT                   AAMDGTVLVNLINTKLTVAVRLAPSTGAVTGEPDVVRKDTHAHAWALRMSPDGNVWGAT
FT                   VNKTAGDAEKLDDVVFPLFPQGGGFPRNNDDKT"
FT   CDS             complement(197451..198065)
FT                   /transl_table=11
FT                   /gene="Mb3032c"
FT                   /locus_tag="Mb3032c"
FT                   /product="POSSIBLE OXIDOREDUCTASE"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb3032c, -, len: 204 aa. Equivalent to Rv3007c, len:
FT                   204 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 204 aa overlap). Possible
FT                   oxidoreductase (EC 1.-.-.-), similar to Q9EWU5|3SC5B7.04c
FT                   PUTATIVE OXIDOREDUCTASE from Streptomyces coelicolor (162
FT                   aa), FASTA scores: opt: 376, E(): 1.5e-18, (41.35% identity
FT                   in 150 aa overlap); Q9K416|SCG22.29c PUTATIVE
FT                   FLAVIN-DEPENDENT REDUCTASE PROTEIN from Streptomyces
FT                   coelicolor (169 aa), FASTA scores: opt: 246, E(): 1e-09,
FT                   (34.1% identity in 135 aa overlap); and some similarity to
FT                   coupling proteins of 4-hydroxyphenylacetic
FT                   hydroxylase/monooxygenase e.g. Q9HWT6|HPAC|PA4092
FT                   Pseudomonas aeruginosa (170 aa), FASTA score: opt: 214;
FT                   O68232|HPAC Photorhabdus luminescens (Xenorhabdus
FT                   luminescens) (172 aa), FASTA score: opt: 198; Q9RPU2|HPAC
FT                   Salmonella dublin (170 aa), FASTA score: opt: 197; etc.
FT                   Equivalent to AAK47416 from Mycobacterium tuberculosis
FT                   strain CDC1551 (236 aa) but shorter 32 aa. Start chosen by
FT                   similarity."
FT                   /db_xref="GOA:Q7TXG4"
FT                   /db_xref="InterPro:IPR012349"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG4"
FT                   /protein_id="CAD96719.1"
FT                   /translation="MSEDVARIHDGDVIDESFDELMGMLDHPVFVVTTQADGHPAGCLV
FT                   SFATQTSVQPPSFMVGLPRSTGTSEVASRSEHLAVHVLSQRQHVLAELFGSQTEEEVNK
FT                   FARCSWRAGPCGMPILDDAAAWFIGRTASRSDVGDYVAYLLEPVSVWAPECSEDLLYLS
FT                   DLDFDVDDIDPGKEASPRFYERERGDETRRYGVVRFTLDVP"
FT   CDS             198259..198882
FT                   /transl_table=11
FT                   /gene="Mb3033"
FT                   /locus_tag="Mb3033"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb3033, -, len: 207 aa. Equivalent to Rv3008, len:
FT                   207 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 207 aa overlap). Hypothetical unknown
FT                   protein. Start uncertain."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG3"
FT                   /protein_id="CAD96720.1"
FT                   /translation="MLTVVAVIGILECGLVLHMPDNDLWYCGPWTLWVMAGRGVASGAG
FT                   VWRGDRVATPLAVAITAAGLVSGARIGPGAAAKRDPQLAQWNEIRSHYQEIAEWIDHDT
FT                   ATAHPAVAATQISAAGSFGRANMVDYLGLLDSRADETVRRDEFSRWLSAKPDYLVTTEQ
FT                   SVDAATIALPEFRHAYDRAATIGTLNVYRRNSPDGDEPLPADGN"
FT   CDS             complement(198879..200408)
FT                   /transl_table=11
FT                   /gene="gatB"
FT                   /locus_tag="Mb3034c"
FT                   /product="PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE
FT                   (SUBUNIT B) GATB (Glu-ADT SUBUNIT B)"
FT                   /EC_number="6.3.5.-"
FT                   /note="Mb3034c, gatB, len: 509 aa. Equivalent to Rv3009c,
FT                   len: 509 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 509 aa overlap). Probable gatB, Glu-
FT                   tRNA-Gln amidotransferase, subunit B (EC 6.3.5.-),
FT                   equivalent to O33107|GATB_MYCLE|MLCB637_15
FT                   GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium
FT                   leprae (509 aa), FASTA scores: opt: 2973, E(): 2.9e-173,
FT                   (88.4% identity in 509 aa overlap). Also highly similar to
FT                   other Glu- tRNA-Gln amidotransferases e.g.
FT                   Q9Z578|GATB|SC8D9.13 from Streptomyces coelicolor (504 aa),
FT                   FASTA scores: opt: 2264, E(): 3.6e-130, (66.0% identity in
FT                   495 aa overlap); P74215|GATB_SYNY3|SLL1435 from
FT                   Synechocystis sp. strain PCC 6803 (519 aa), FASTA scores:
FT                   opt: 1289, E(): 6.7e-71, (42.0% identity in 485 aa
FT                   overlap); Q9X100|GATB_THEMA|TM1273 GLUTAMYL-TRNA(GLN)
FT                   AMIDOTRANSFERASE from Thermotoga maritima (482 aa), FASTA
FT                   scores: opt: 1165, E(): 2.2e-63, (40.05% identity in 487 aa
FT                   overlap); etc. For more information about function, see
FT                   citation below. Similar to many members of the pet112
FT                   family. BELONGS TO THE GATB FAMILY."
FT                   /db_xref="GOA:P64200"
FT                   /db_xref="InterPro:IPR017958"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64200"
FT                   /protein_id="CAD96721.1"
FT                   /translation="MTVAAGAAKAAGAELLDYDEVVARFQPVLGLEVHVELSTATKMFC
FT                   GCTTTFGGEPNTQVCPVCLGLPGSLPVLNRAAVESAIRIGLALNCEIVPWCRFARKNYF
FT                   YPDMPKNYQISQYDEPIAINGYLDAPLEDGTTWRVEIERAHMEEDTGKLTHIGSETGRI
FT                   HGATGSLIDYNRAGVPLIEIVTKPIVGAGARAPQIARSYVTALRDLLRALDVSDVRMDQ
FT                   GSMRCDANVSLKPAGTTEFGTRTETKNVNSLKSVEVAVRYEMQRQGAILASGGRITQET
FT                   RHFHEAGYTSAGRTKETAEDYRYFPEPDLEPVAPSRELVERLRQTIPELPWLSRRRIQQ
FT                   EWGVSDEVMRDLVNAGAVELVAATVEHGASSEAARAWWGNFLAQKANEAGIGLDELAIT
FT                   PAQVAAVVALVDEGKLSNSLARQVVEGVLAGEGEPEQVMTARGLALVRDDSLTQAAVDE
FT                   ALAANPDVADKIRGGKVAAAGAIVGAVMKATRGQADAARVRELVLEACGQG"
FT   CDS             complement(200438..201469)
FT                   /transl_table=11
FT                   /gene="pfkA"
FT                   /locus_tag="Mb3035c"
FT                   /product="PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA
FT                   (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)"
FT                   /EC_number="2.7.1.11"
FT                   /note="Mb3035c, pfkA, len: 343 aa. Equivalent to Rv3010c,
FT                   len: 343 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 343 aa overlap). Probable pfkA,
FT                   phosphofructokinase (EC 2.7.1.11), equivalent to
FT                   O33106|K6PF_MYCLE|MLCB637.14 6-PHOSPHOFRUCTOKINASE from
FT                   Mycobacterium leprae (343 aa), FASTA scores: opt: 2099,
FT                   E(): 4.1e-122, (90.4% identity in 343 aa overlap). Also
FT                   highly similar to others e.g. Q9FC99|K6P3_STRCO from
FT                   Streptomyces coelicolor (341 aa), FASTA scores: opt: 1329,
FT                   E(): 1.1e-74, (58.9% identity in 338 aa overlap);
FT                   Q9L1L8|K6P2_STRCO|PFKA2|PFK2|SC6A11.02
FT                   6-PHOSPHOFRUCTOKINASE 2 from Streptomyces coelicolor (341
FT                   aa), FASTA scores: opt: 1303, E(): 4.5e-73, (56.7% identity
FT                   in 342 aa overlap); Q9KH71|PFP PPI-DEPENDENT
FT                   PHOSPHOFRUCTOKINASE from Dictyoglomus thermophilum (346
FT                   aa), FASTA scores: opt: 893, E(): 8.4e-48, (41.85% identity
FT                   in 344 aa overlap); etc. Contains PS00433
FT                   Phosphofructokinase signature. BELONGS TO THE
FT                   PHOSPHOFRUCTOKINASE FAMILY."
FT                   /db_xref="GOA:P65691"
FT                   /db_xref="HSSP:3PFK"
FT                   /db_xref="InterPro:IPR015912"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65691"
FT                   /protein_id="CAD96722.1"
FT                   /translation="MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLL
FT                   ENRRVQLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIPIGGE
FT                   GTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHER
FT                   VMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIEEVCRLVKGRFQRGDSHFICVVA
FT                   EGAKPAPGTIMLREGGLDEFGHERFTGVAAQLAVEVEKRINKDVRVTVLGHIQRGGTPT
FT                   AYDRVLATRFGVNAADAAHAGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAA
FT                   FFG"
FT   CDS             complement(201565..203049)
FT                   /transl_table=11
FT                   /gene="gatA"
FT                   /locus_tag="Mb3036c"
FT                   /product="PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE
FT                   (SUBUNIT A) GATA (Glu-ADT SUBUNIT A)"
FT                   /EC_number="6.3.5.-"
FT                   /note="Mb3036c, gatA, len: 494 aa. Equivalent to Rv3011c,
FT                   len: 494 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.4% identity in 494 aa overlap). Probable gatA,
FT                   Glu-tRNA-Gln amidotransferase, subunit A (EC 6.3.5.-),
FT                   equivalent to O33105|GATA|ML1702|MLCB637.13
FT                   GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium
FT                   leprae (497 aa), FASTA scores: opt: 2839, E(): 3.5e-161,
FT                   (88.8% identity in 492 aa overlap). Also highly similar to
FT                   other Glu-tRNA-Gln amidotransferases e.g. Q9Z580|GATA_STRCO
FT                   from Streptomyces coelicolor (497 aa), FASTA scores: opt:
FT                   2231, E(): 4.5e-125, (70.3% identity in 486 aa overlap);
FT                   P73558|GATA_SYNY3|SLR0877 from Synechocystis sp. strain PCC
FT                   6803 (483 aa), FASTA scores: opt: 1593, E(): 3.3e-87,
FT                   (55.85% identity in 487 aa overlap); O06491|GATA_BACSU
FT                   GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Bacillus subtilis
FT                   (485 aa), FASTA scores: opt: 1389, E(): 4.3e-75, (51.7%
FT                   identity in 468 aa overlap); etc. For more information
FT                   about function, see citation below. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop). BELONGS TO THE
FT                   AMIDASE FAMILY."
FT                   /db_xref="GOA:Q7TXG2"
FT                   /db_xref="InterPro:IPR004412"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TXG2"
FT                   /protein_id="CAD96723.1"
FT                   /translation="MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAFL
FT                   HVAADEALAAAAAVDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSP
FT                   YDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAA
FT                   LAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTV
FT                   LDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQP
FT                   GVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRV
FT                   GDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLD
FT                   AAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDD
FT                   GLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI"
FT   CDS             complement(203046..203345)
FT                   /transl_table=11
FT                   /gene="gatC"
FT                   /locus_tag="Mb3037c"
FT                   /product="PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE
FT                   (SUBUNIT C) GATC (Glu-ADT SUBUNIT C)"
FT                   /EC_number="6.3.5.-"
FT                   /note="Mb3037c, gatC, len: 99 aa. Equivalent to Rv3012c,
FT                   len: 99 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 99 aa overlap). Probable gatC,
FT                   Glu-tRNA-Gln amidotransferase, subunit C (EC 6.3.5.-),
FT                   equivalent to O33104|GATC_MYCLE|MLCB637.12
FT                   GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium
FT                   leprae (99 aa), FASTA scores: opt: 483, E(): 3.1e-25,
FT                   (74.75% identity in 99 aa overlap). Also highly similar to
FT                   other Glu-tRNA-Gln amidotransferases e.g.
FT                   Q9Z581|GATC_STRCO|SC8D9.10 from Streptomyces coelicolor (98
FT                   aa), FASTA scores: opt: 298, E(): 4e-13, (53.7% identity in
FT                   95 aa overlap); O06492|GATC_BACSU from B. subtilis (96 aa),
FT                   FASTA scores: opt: 222, E(): 3.7e-08, (43.15% identity in
FT                   95 aa overlap); Q9KF29|BH0665 from Bacillus halodurans (96
FT                   aa), FASTA scores: opt: 211, E(): 1.9e-07, (41.05% identity
FT                   in 95 aa overlap); etc. For more information about
FT                   function, see citation below. BELONGS TO THE GATC FAMILY."
FT                   /db_xref="GOA:P64206"
FT                   /db_xref="InterPro:IPR003837"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64206"
FT                   /protein_id="CAD96724.1"
FT                   /translation="MSQISRDEVAHLARLARLALTETELDSFAGQLDAILTHVSQIQAV
FT                   DVTGVQATDNPLKDVNVTRPDETVPCLTQRQVLDQAPDAVDGRFAVPQILGDEQ"
FT   CDS             203430..204086
FT                   /transl_table=11
FT                   /gene="Mb3038"
FT                   /locus_tag="Mb3038"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3038, -, len: 218 aa. Equivalent to Rv3013, len:
FT                   218 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 218 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O33103|MLCB637_11c HYPOTHETICAL 24.4
FT                   KDA PROTEIN from Mycobacterium leprae (230 aa), FASTA
FT                   scores: opt: 1188, E(): 2.6e-67, (83.95% identity in 218 aa
FT                   overlap). Equivalent to AAK47422 from Mycobacterium
FT                   tuberculosis strain CDC1551 (240 aa) but shorter 22 aa."
FT                   /db_xref="GOA:Q7TXG1"
FT                   /db_xref="InterPro:IPR002912"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG1"
FT                   /protein_id="CAD96725.1"
FT                   /translation="MRSYLLRIELADRPGSLGSLAVALGSVGADILSLDVVERGNGYAI
FT                   DDLVVELPPGAMPDTLITAAEALNGVRVDSVRPHTGLLEAHRELELLDHVAAAEGATAR
FT                   LQVLVNEAPRVLRVSWCTVLRSSGGELHRLAGSPGAPETRANSAPWLPIERAAALDGGA
FT                   DWVPQAWRDMDTTMVAAPLGDTHTAVVLGRPGPEFRPSEVARLGYLAGIVATMLR"
FT   CDS             complement(204160..206235)
FT                   /transl_table=11
FT                   /gene="ligA"
FT                   /locus_tag="Mb3039c"
FT                   /standard_name="lig"
FT                   /product="PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA
FT                   (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+])"
FT                   /EC_number="6.5.1.2"
FT                   /note="Mb3039c, ligA, len: 691 aa. Equivalent to Rv3014c,
FT                   len: 691 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 691 aa overlap). Probable ligA
FT                   (alternate gene name: lig), DNA ligase NAD-dependent (EC
FT                   6.5.1.2), equivalent to
FT                   O33102|DNLJ_MYCLE|LIGA|LIG|ML1705|MLCB637.10 DNA LIGASE
FT                   from Mycobacterium leprae (694 aa), FASTA scores: opt:
FT                   3844, E(): 0, (84.7% identity in 687 aa overlap). Also
FT                   highly similar to many prokaryotic and eukaryotic ligases
FT                   e.g. Q9Z585|LIGA|SC8D9.06 from Streptomyces coelicolor (735
FT                   aa), FASTA scores: opt: 2002, E(): 4e-113, (59.4% identity
FT                   in 714 aa overlap); P49421|DNLJ_RHOMR|LIGA|LIG from
FT                   Rhodothermus marinus (712 aa), FASTA scores: opt: 1835,
FT                   E(): 4.6e-103, (45.55% identity in 685 aa overlap);
FT                   P15042|DNLJ_ECOLI|LIGA|LIG|DNAL|PDEC|LOP|B2411 from
FT                   Escherichia coli strain K12 (671 aa), FASTA scores: opt:
FT                   1696, E(): 1.1e-94, (43.8% identity in 680 aa overlap);
FT                   etc. BELONGS TO THE NAD-DEPENDENT DNA LIGASE FAMILY."
FT                   /db_xref="GOA:P63974"
FT                   /db_xref="HSSP:1B04"
FT                   /db_xref="InterPro:IPR004149"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63974"
FT                   /protein_id="CAD96726.1"
FT                   /translation="MSSPDADQTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFD
FT                   ELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAW
FT                   AGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADV
FT                   PERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKD
FT                   PAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERID
FT                   YWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDIRVN
FT                   VGRTGRITPFAFMTPVKVAGSTVGQATLHNASEIKRKGVLIGDTVVIRKAGDVIPEVLG
FT                   PVVELRDGSEREFIMPTTCPECGSPLAPEKEGDADIRCPNARGCPGQLRERVFHVASRN
FT                   GLDIEVLGYEAGVALLQAKVIADEGELFALTERDLLRTDLFRTKAGELSANGKRLLVNL
FT                   DKAKAAPLWRVLVALSIRHVGPTAARALATEFGSLDAIAAASTDQLAAVEGVGPTIAAA
FT                   VTEWFAVDWHREIVDKWRAAGVRMVDERDESVPRTLAGLTIVVTGSLTGFSRDDAKEAI
FT                   VARGGKAAGSVSKKTNYVVAGDSPGSKYDKAVELGVPILDEDGFRRLLADGPASRT"
FT   CDS             complement(206266..207279)
FT                   /transl_table=11
FT                   /gene="Mb3040c"
FT                   /locus_tag="Mb3040c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3040c, -, len: 337 aa. Equivalent to Rv3015c, len:
FT                   337 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 337 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBR6|ML1706 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (337 aa), FASTA scores: opt:
FT                   1703, E(): 3.1e-92, (78.05% identity in 337 aa overlap);
FT                   and (but longer 47 aa) O33101|MLCB637.09 HYPOTHETICAL 30.0
FT                   KDA PROTEIN from Mycobacterium leprae (290 aa), FASTA
FT                   scores: opt: 1564, E(): 2.4e-78, (78.6% identity in 290 aa
FT                   overlap). Also similar to Q9Z586|SC8D9.05 HYPOTHETICAL 35.0
FT                   KDA PROTEIN from Streptomyces coelicolor (331 aa), FASTA
FT                   scores: opt: 774, E(): 4.7e-38, (43.4% identity in 334 aa
FT                   overlap); and showing similarity with other proteins e.g.
FT                   Q39586|METE_CHLRE
FT                   5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE
FT                   METHYLTRANSFERASE from Chlamydomonas reinhardtii (814 aa),
FT                   FASTA scores: opt: 162, E(): 0.048, (27.05% identity in 355
FT                   aa overlap)."
FT                   /db_xref="GOA:Q7TXG0"
FT                   /db_xref="InterPro:IPR002629"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXG0"
FT                   /protein_id="CAD96727.1"
FT                   /translation="MSVFATATGIGSWPGTAAREAAQVVVGELAGALAYLTELPARGVG
FT                   ADMLGRAGGLLVDVAIDTVPRGYRIAARPGAVTRRAASLLDEDMDALEEAWETAGLRGC
FT                   GRAVKVQAPGPVTLVAGLELANGHRAITDPGAVRDLAASLAEGVAAHRAALARRLDTPV
FT                   VVQFDEPSLPAALGGRLTGVTALSPVAPLDETVAEALLDTCIAAVDADVALHSCSPDLP
FT                   WDLLQRSRISAVSVDASTLQAADLDAVAAFVESGRTVVLGLVPVTAPERAPSMEEVAAA
FT                   AVAVTDRLGVPRSALRDRLGVSPACGLANATGQWARTAVGLARDVAEAFARDPEAI"
FT   CDS             207373..208002
FT                   /transl_table=11
FT                   /gene="lpqA"
FT                   /locus_tag="Mb3041"
FT                   /product="PROBABLE LIPOPROTEIN LPQA"
FT                   /note="Mb3041, lpqA, len: 209 aa. Equivalent to Rv3016,
FT                   len: 209 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 209 aa overlap). Probable lpqA,
FT                   lipoprotein. Contains signal sequence and appropriately
FT                   positioned PS00013 Prokaryotic membrane lipoprotein lipid
FT                   attachment site."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF9"
FT                   /protein_id="CAD96728.1"
FT                   /translation="MVGLTRPLLLCGATLLIAACTRVVGGTASATFGGDRQGMLDVATI
FT                   LLDQSRMQAITGSGDDLTIIPTMDTTYPVDVDDFAQPIPRECRFIYAETAVFGSEIEAF
FT                   HKTTFQDRPDGSLISEAAAAYRDAGTARRAFDTLAVTVHDCAASPAGWLFVSRWTAGGN
FT                   SLHIRAGDCGRDYRVLSAALLEVTFCGFPESVSDIVMTNIAANVPG"
FT   CDS             complement(208105..208467)
FT                   /transl_table=11
FT                   /gene="esxQ"
FT                   /locus_tag="Mb3042c"
FT                   /standard_name="ES6_8; TB12.9"
FT                   /product="PUTATIVE ESAT-6 LIKE PROTEIN 8"
FT                   /note="Mb3042c, esxQ, len: 120 aa. Equivalent to Rv3017c,
FT                   len: 120 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 120 aa overlap). esxQ, putative ESAT-6
FT                   like protein 8, possibly secreted protein, very similar to
FT                   AAK47433|MT3104 PUTATIVE SECRETED ESAT-6 LIKE PROTEIN 9
FT                   from Mycobacterium tuberculosis strain CDC1551 (96 aa),
FT                   FASTA scores: opt: 315, E(): 1.2e-14, (65.7% identity in 70
FT                   aa overlap); Rv3019c|O53266|MTV012.33c PUTATIVE SECRETED
FT                   ESAT-6 LIKE PROTEIN 9 from Mycobacterium tuberculosis (96
FT                   aa), FASTA scores: opt: 315, E(): 1.2e-14, (65.7% identity
FT                   in 70 aa overlap) and Rv0288|O53693|CFP7|MT0301|MTV035.16
FT                   10 KDA ANTIGEN CFP7 (LOW MOLECULAR WEIGHT PROTEIN ANTIGEN
FT                   7) (CFP-7) from Mycobacterium tuberculosis (95 aa), FASTA
FT                   scores: opt: 303, E(): 7.4e-14, (66.2% identity in 68 aa
FT                   overlap). BELONGS TO THE ESAT6 FAMILY."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64092"
FT                   /protein_id="CAD96729.1"
FT                   /translation="MSQSMYSYPAMTANVGDMAGYTGTTQSLGADIASERTAPSRACQG
FT                   DLGMSHQDWQAQWNQAMEALARAYRRCRRALRQIGVLERPVGDSSDCGTIRVGSFRGRW
FT                   LDPRHAGPATAADAGD"
FT   CDS             complement(208554..209867)
FT                   /transl_table=11
FT                   /gene="PPE46"
FT                   /locus_tag="Mb3043c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb3043c, PPE46, len: 437 aa. Equivalent to Rv3018c,
FT                   len: 434 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.5% identity in 431 aa overlap). Member of PPE family
FT                   but lacks Gly, Ala rich repeats at C-terminal domain,
FT                   closest to MTCY261.19. Also very similar to following ORF
FT                   MTV012.35c. Nearly identical in parts to Mycobacterium
FT                   tuberculosis protein erroneously described as DIHYDROFOLATE
FT                   REDUCTASE (X59271|MTFOLA_1) P31500|DYR_MYCTU (214 aa),
FT                   FASTA scores: opt: 972, E(): 4.4e-42, (80.0% identity in
FT                   195 aa overlap); and Z97559|MTCY261_19 from M. tuberculosis
FT                   cosmid (473 aa), FASTA scores: opt: 806, E(): 0; (38.8%
FT                   identity in 479 aa overlap); and O53268|MTV012.35c from
FT                   Mycobacterium tuberculosis (358 aa), FASTA scores: opt:
FT                   1714, E(): 3.3e-79, (78.3% identity in 355 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 56
FT                   bp deletion leads to a product slightly different at the
FT                   Nh2-terminus part compared to its homolog in Mycobacterium
FT                   tuberculosis strain H37Rv (434 aa versus 437 aa)."
FT                   /db_xref="InterPro:IPR000030"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF8"
FT                   /protein_id="CAD96730.1"
FT                   /translation="MSSHRTPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYA
FT                   AVAQELSAVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYV
FT                   CALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAV
FT                   VGAALVATPHTGPAPVIVKPGANEASNAVAAATITPFPWHEIVQFLEETFAAYDQYLSA
FT                   LLSELPAVAWVWFQLFVDILGFNIIGFIITLASNAQLLTEFAINASYVAVGLLYAIAGV
FT                   IDIVVEWVIGNLFGVVPLLGGPLLGALAAAVVPGVAGLAGVAGLAAVPAVGAAAGAPAA
FT                   LVGSVAPVSGGVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPA
FT                   GLTVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV"
FT   CDS             complement(209888..209974)
FT                   /transl_table=11
FT                   /gene="PE27A"
FT                   /locus_tag="Mb3044c"
FT                   /product="PE family protein"
FT                   /note="Mb3044c, PE27A, len: 28 aa. Equivalent to Rv3018A,
FT                   len: 28 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 28 aa overlap). Member of M.
FT                   tuberculosis PE family, most similar to Rv0285 (102 aa),
FT                   FASTA scores: opt: 147, E(): 3.5e-05, (92.85% identity in
FT                   28 aa overlap); etc."
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL4"
FT                   /protein_id="CAD96731.1"
FT                   /translation="MTLSVVPEGLAAASAAVEALTARLAAAH"
FT   CDS             complement(210270..210560)
FT                   /transl_table=11
FT                   /gene="esxR"
FT                   /locus_tag="Mb3045c"
FT                   /standard_name="ES6_9; TB10.3"
FT                   /product="PUTATIVE SECRETED ESAT-6 LIKE PROTEIN 9 TB10.3"
FT                   /note="Mb3045c, esxR, len: 96 aa. Equivalent to Rv3019c,
FT                   len: 96 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 96 aa overlap). esxR, putative secreted
FT                   ESAT-6 like protein 9 (see citations below), most similar
FT                   to O53693|AAK44525|Rv0288|CFP7|MT0301|MTV035.16 10 KDA
FT                   ANTIGEN CFP7 (LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7)
FT                   (CFP-7) from Mycobacterium tuberculosis (95 aa), FASTA
FT                   scores: opt: 566, E(): 5.1e-31, (84.3% identity in 95 aa
FT                   overlap). Also similar to Q9CD33|ML2531 POSSIBLE CELL
FT                   SURFACE PROTEIN from Mycobacterium leprae (96 aa), FASTA
FT                   scores: opt: 472, E(): 8.3e-25, (66.6% identity in 96 aa
FT                   overlap); O53264|Rv3017c|MTV012.31c PUTATIVE SECRETED
FT                   ANTIGEN from Mycobacterium tuberculosis (120 aa), FASTA
FT                   scores: opt: 321, E(): 9.6e-15, (67.15% identity in 70 aa
FT                   overlap);
FT                   Q57165|AAK48357|O84901|X79562|ESAT6|Rv3875|MT3989|MTV027.10
FT                   esat6 gene from Mycobacterium tuberculosis strain Erdman
FT                   (94 aa), FASTA scores: opt: 131, E(): 0.028, (26.1%
FT                   identity in 88 aa overlap). BELONGS TO THE ESAT6 FAMILY.
FT                   TBparse score is 0.906."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64094"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96732.1"
FT                   /translation="MSQIMYNYPAMMAHAGDMAGYAGTLQSLGADIASEQAVLSSAWQG
FT                   DTGITYQGWQTQWNQALEDLVRAYQSMSGTHESNTMAMLARDGAEAAKWGG"
FT   CDS             complement(210595..210888)
FT                   /transl_table=11
FT                   /gene="esxS"
FT                   /locus_tag="Mb3046c"
FT                   /standard_name="PE28"
FT                   /product="PE FAMILY PROTEIN"
FT                   /note="Mb3046c, esxS, len: 97 aa. Equivalent to Rv3020c,
FT                   len: 97 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 97 aa overlap). Member of Mycobacterium
FT                   tuberculosis PE family (see first citation below), similar
FT                   to others e.g. AAK44524|MT0300 PE FAMILY PROTEIN from M.
FT                   tuberculosis strain CDC1551 (97 aa), FASTA scores: opt:
FT                   564, E(): 5.9e-30, (91.75% identity in 97 aa overlap). Has
FT                   potential helix-turn-helix motif at positions 14-35.
FT                   TBparse score is 0.912. SEEMS TO BELONG TO THE ESAT6 FAMILY
FT                   (see second citation below)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96733.1"
FT                   /translation="MSLLDAHIPQLIASHTAFAAKAGLMRHTIGQAEQQAMSAQAFHQG
FT                   ESAAAFQGAHARFVAAAAKVNTLLDIAQANLGEAAGTYVAADAAAASSYTGF"
FT   CDS             complement(210935..212242)
FT                   /transl_table=11
FT                   /gene="PPE47"
FT                   /locus_tag="Mb3047c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb3047c, PPE47, len: 435 aa. Equivalent to Rv3022c
FT                   (PPE48) and Rv3021c (PPE47), len: 81 aa and 358 aa, from
FT                   Mycobacterium tuberculosis strain H37Rv, (98.8% identity in
FT                   81 aa overlap and 98.6% identity in 354 aa overlap). Member
FT                   of Mycobacterium tuberculosis PPE family. Should be
FT                   continuation of upstream ORF MTV012.36c but is frameshifted
FT                   due to missing base at 36448 in v012. Sequence has been
FT                   checked but no error apparent. Very similar to neighbouring
FT                   ORF O53265|MTV012.32c|Rv3018c from Mycobacterium
FT                   tuberculosis (434 aa), FASTA scores: opt: 1714, E():
FT                   6.6e-770, (78.3% identity in 355 aa overlap) and
FT                   AAK47430|MT3101 (strongly in the N-terminal part) (310 aa),
FT                   FASTA scores: opt: 897, E(): 4.5e-37, (66.95% identity in
FT                   227 aa overlap). REMARK-M.bovis-M.tuberculosis: In
FT                   Mycobacterium tuberculosis H37Rv, PPE47 and PPE48 exist as
FT                   2 separate genes. In Mycobacterium bovis, a single base
FT                   insertion (*-g) leads to a single product."
FT                   /db_xref="InterPro:IPR000030"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF6"
FT                   /protein_id="CAD96734.1"
FT                   /translation="MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYAAVA
FT                   QELSAVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYVCAL
FT                   AEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAVVGA
FT                   ALVATPHTGPAPVIVKPGANEASNAVAAATITPFPFGELAKFLEMAAQAFTEVGELIMK
FT                   SAEAWAVGFVELITGLVNFEPWLVLTGMIDMFFATVGFALGVFVLVPLLEFAVVLELAI
FT                   LSIGWIISNIFGAIPVLAGPLLGALAAAVVPGVAGVTGLAGLAAVPAVGAAAGAPAALV
FT                   GSVAPVSGGVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPAGL
FT                   TVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV"
FT   CDS             complement(212239..212553)
FT                   /transl_table=11
FT                   /gene="PE29"
FT                   /locus_tag="Mb3048c"
FT                   /product="PE FAMILY PROTEIN"
FT                   /note="Mb3048c, PE29, len: 104 aa. Equivalent to Rv3022A,
FT                   len: 104 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 104 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PE family, similar to many
FT                   others e.g. Rv0285|AL021930_12 from Mycobacterium
FT                   tuberculosis (102 aa), FASTA scores: opt: 497, E(): 3e-21,
FT                   (80.39% identity in 102 aa overlap); etc."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF5"
FT                   /protein_id="CAD96735.1"
FT                   /translation="MTLRVVPEGLAAASAAVEALTARLAAAHAGAAPAITAVVAPAADP
FT                   VSLQSAVGFSALGSEHAAIAGEGVEELGRSGVAVGESGIGYAAGDAVAAATYLVSGGSL
FT                   "
FT   repeat_region   212865..212872
FT                   /rpt_type=DIRECT
FT                   /note="8 bp direct repeat, CCAGTCGC, flanking IS element
FT                   IS1081."
FT   repeat_region   complement(212873..214307)
FT                   /mobile_element="insertion sequence:IS1081"
FT                   /locus_tag="IS1081-5"
FT                   /note="IS1081-5, len: 1435 nt. Equivalent to IS1081, len:
FT                   1450 nt, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 1435 nt overlap)."
FT   repeat_region   212911..212925
FT                   /rpt_type=INVERTED
FT                   /note="15 bp perfect inverted repeat, IRR, TCGCGTGATCCTTCG,
FT                   flanking IS element IS1081."
FT   CDS             complement(212935..214182)
FT                   /transl_table=11
FT                   /gene="Mb3049c"
FT                   /locus_tag="Mb3049c"
FT                   /product="PROBABLE TRANSPOSASE"
FT                   /note="Mb3049c, -, len: 415 aa. Equivalent to Rv3023c, len:
FT                   415 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 415 aa overlap). Probable IS1081
FT                   transposase. Contains PS01007 Transposases, Mutator family,
FT                   signature. Similars to
FT                   P35882|TRA1_MYCTU|Rv1199c|MTCI364.11c and
FT                   Rv2512c|MTCY07A7.18c TRANSPOSASES FOR INSERTION SEQUENCE
FT                   ELEMENT IS1081 (415 aa), FASTA scores: opt: 2675, E():
FT                   1.8e-162, (100.0% identity in 415 aa overlap). TBparse
FT                   score is 0.894. BELONGS TO THE MUTATOR FAMILY OF
FT                   TRANSPOSASE."
FT                   /db_xref="GOA:P60231"
FT                   /db_xref="InterPro:IPR001207"
FT                   /db_xref="UniProtKB/Swiss-Prot:P60231"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96736.1"
FT                   /translation="MTSSHLIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALC
FT                   GAGYRERSDERSNQRNGYRHRDFDTRAATIDVAIPKLRQGSYFPDWLLQRRKRAERALT
FT                   SVVATCYLLGVSTRRMERLVETLGVTKLSKSQVSIMAKELDEAVEAFRTRPLDAGPYTF
FT                   LAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVTSAEDGAGWLAFFRDLVAR
FT                   GLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYAANLMAATPKPSWPWVRTLLHSI
FT                   YDQPDAESVVAQYDRVLDALTDKLPAVAEHLDTARTDLLAFTAFPKQIWRQIWSNNPQE
FT                   RLNREVRRRTDVVGIFPDRASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTST
FT                   EEPAKQQTTNTPALTT"
FT   repeat_region   complement(214220..214234)
FT                   /rpt_type=INVERTED
FT                   /note="15 bp perfect inverted repeat, IRL, TCGCGTGATCCTTCG,
FT                   flanking IS element IS1081."
FT   repeat_region   214308..214315
FT                   /rpt_type=DIRECT
FT                   /note="8 bp direct repeat, CCAGTCGC, flanking IS element
FT                   IS1081."
FT   CDS             complement(214345..215448)
FT                   /transl_table=11
FT                   /gene="trmU"
FT                   /locus_tag="Mb3050c"
FT                   /product="PROBABLE tRNA
FT                   (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE
FT                   TRMU"
FT                   /EC_number="2.1.1.61"
FT                   /note="Mb3050c, trmU, len: 367 aa. Equivalent to Rv3024c,
FT                   len: 367 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 367 aa overlap). Probable trmU, tRNA
FT                   (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC
FT                   2.1.1.61), equivalent to
FT                   O33099|TRMU_MYCLE|ML1707|MLCB637.07 PROBABLE tRNA
FT                   (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE
FT                   from Mycobacterium leprae (358 aa), FASTA scores: opt:
FT                   2033, E(): 5.5e-116, (85.45% identity in 357 aa overlap).
FT                   Also highly similar to others e.g.
FT                   O86583|TRMU_STRCO|SC2A11.22 from Streptomyces coelicolor
FT                   (376 aa), FASTA scores: opt: 1336, E(): 1e-73, (56.9%
FT                   identity in 369 aa overlap); BAB49856|MLR2824 from
FT                   Rhizobium loti (378 aa), FASTA scores: opt: 826, E():
FT                   8.3e-43, (42.35% identity in 359 aa overlap);
FT                   Q9ZDM1|TRMU_RICPR|RP306 from Rickettsia prowazekii (358
FT                   aa), FASTA scores: opt: 800, E(): 3e-41, (40.1% identity in
FT                   359 aa overlap); etc. BELONGS TO THE TRMU FAMILY."
FT                   /db_xref="GOA:P66977"
FT                   /db_xref="InterPro:IPR018318"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66977"
FT                   /protein_id="CAD96737.1"
FT                   /translation="MKVLAAMSGGVDSSVAAARMVDAGHEVVGVHMALSTAPGTLRTGS
FT                   RGCCSKEDAADARRVADVLGIPFYVWDFAEKFKEDVINDFVSSYARGETPNPCVRCNQQ
FT                   IKFAALSARAVALGFDTVATGHYARLSGGRLRRAVDRDKDQSYVLAVLTAQQLRHAAFP
FT                   IGDTPKRQIRAEAARRGLAVANKPDSHDICFIPSGNTKAFLGERIGVRRGVVVDADGVV
FT                   LASHDGVHGFTIGQRRGLGIAGPGPNGRPRYVTAIDADTATVHVGDVTDLDVQTLTGRA
FT                   PVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRP
FT                   DPAGDEVLGSATIAGASGLSTGGNPGA"
FT   CDS             complement(215445..216626)
FT                   /transl_table=11
FT                   /gene="iscS"
FT                   /locus_tag="Mb3051c"
FT                   /standard_name="nifS"
FT                   /product="PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN
FT                   HOMOLOG) (NITROGENASE METALLOCLUSTERS BIOSYNTHESIS PROTEIN
FT                   NIFS)"
FT                   /EC_number="4.4.1.-"
FT                   /note="Mb3051c, iscS, len: 393 aa. Equivalent to Rv3025c,
FT                   len: 393 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 393 aa overlap). Probable iscS
FT                   (alternate gene name: nifS), cysteine desulfurase
FT                   (NifS-like protein) (EC 4.4.1.-), equivalent to
FT                   MLCB637.06|O33098 NIFS-LIKE PROTEIN from Mycobacterium
FT                   leprae (396 aa), FASTA scores: opt: 2186, E(): 2.7e-122,
FT                   (84.9% identity in 391 aa overlap). Also highly similar to
FT                   many e.g. O86581|SC2A11.20 PUTATIVE
FT                   PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASE from
FT                   Streptomyces coelicolor (389 aa), FASTA scores: opt: 1568,
FT                   E(): 1.1e-85, (61.7% identity in 389 aa overlap);
FT                   P57795|ISCS|NIFS CYSTEINE DESULFURASE (NIFS PROTEIN
FT                   HOMOLOG) from Methanosarcina thermophila (404 aa), FASTA
FT                   scores: opt: 1059, E(): 1.6e-55, (46.2% identity in 381 aa
FT                   overlap); O54055|ISCS_RUMFL|ISCS|NIFS CYSTEINE DESULFURASE
FT                   from Ruminococcus flavefaciens (396 aa), FASTA scores: opt:
FT                   973, E(): 2e-50, (43.3% identity in 381 aa overlap);
FT                   P57794|NIFS_ACEDI CYSTEINE DESULFURASE from Acetobacter
FT                   diazotrophicus (400 aa), FASTA scores: opt: 958, E():
FT                   1.6e-49, (41.1% identity in 392 aa overlap); etc. Also
FT                   similar to Rv1464|MTV007.11 from Mycobacterium
FT                   tuberculosis. Contains PS00595 Aminotransferases class-V
FT                   pyridoxal-phosphate attachment site. BELONGS TO CLASS-V OF
FT                   PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES, NIFS/ISCS
FT                   SUBFAMILY. COFACTOR: PYRIDOXAL PHOSPHATE (BY SIMILARITY)."
FT                   /db_xref="GOA:Q7TXF4"
FT                   /db_xref="HSSP:1EG5"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF4"
FT                   /protein_id="CAD96738.1"
FT                   /translation="MAYLDHAATTPMHPAAIEAMAAVQRTIGNASSLHTSGRSARRRIE
FT                   EARELIADKLGARPSEVIFTAGGTESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVL
FT                   DSVNWLVEHEGAHVTWLPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIA
FT                   EMSVVAMEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRRDVT
FT                   CVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARLRLLRDRLVEGVLAE
FT                   IDDVCLNGADDPMRLAGNAHFTFRGCEGDALLMLLDANGIECSTGSACTAGVAQPSHVL
FT                   IAMGVDAASARGSLRLSLGHTSVEADVDAALEVLPGAVARARRAALAAAGASR"
FT   CDS             complement(216723..217637)
FT                   /transl_table=11
FT                   /gene="Mb3052c"
FT                   /locus_tag="Mb3052c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3052c, -, len: 304 aa. Equivalent to Rv3026c, len:
FT                   304 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 304 aa overlap). Conserved hypothetical
FT                   protein, similar to Q9RCZ0|SCM10.08C PUTATIVE
FT                   ACYLTRANSFERASE from Streptomyces coelicolor (275 aa),
FT                   FASTA scores: opt: 393, E(): 2.2e-17, (41.4% identity in
FT                   299 aa overlap). Similar in part to other hypothetical
FT                   proteins and acyltransferases e.g. BAB51968|MLR5533 from
FT                   Rhizobium loti (266 aa), FASTA scores: opt: 280, E():
FT                   2.4e-10, (29.45% identity in 258 aa overlap); Q9KIH9
FT                   PUTATIVE ACYLTRANSFERASE (PUTATIVE ACYLTRANSFERASE
FT                   TRANSMEMBRANE PROTEIN) (EC 2.3.1.) from Rhizobium meliloti
FT                   (Sinorhizobium meliloti) (292 aa), FASTA scores: opt: 252,
FT                   E(): 1.4e-08, (30.5% identity in 210 aa overlap);
FT                   O69114|PLSC PUTATIVE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE
FT                   ACYLTRANSFERASE from Burkholderia pseudomallei (Pseudomonas
FT                   pseudomallei) (289 aa), FASTA scores: opt: 216, E():
FT                   2.4e-06, (30.85% identity in 269 aa overlap); etc. So may
FT                   be a member of acyltransferase family protein."
FT                   /db_xref="GOA:Q7TXF3"
FT                   /db_xref="InterPro:IPR002123"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF3"
FT                   /protein_id="CAD96739.1"
FT                   /translation="MSAPAVTEHSWLPRATCGVSCVSVGDAAQVRRPLVVLRVALRVML
FT                   ALLLVPGVPLVVMPLPGRTRVQRIYCRLVLRLFGVRITVSGSPVRNLRGVLVVSGHVSW
FT                   LDVFCIGSVLPGSFVARADMFTGRTIGIVARILKIIPIERASLRRLPGVVDTIARRLRA
FT                   GQTVVAFPEGTTWCGRPGDDAGRPAARAGAGCSHRGCGAFYPAMFQAAIDAGRPVQPLR
FT                   LTYHHVDGTVSTAPAFVGDDTLVRSVCRLLTVRRTLAWVRVESLQLPGTDRRNLARRCQ
FT                   SAVLAGALGQSGQRPGRRHVPAT"
FT   CDS             complement(217634..218374)
FT                   /transl_table=11
FT                   /gene="Mb3053c"
FT                   /locus_tag="Mb3053c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3053c, -, len: 246 aa. Equivalent to Rv3027c, len:
FT                   246 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 246 aa overlap). Conserved hypothetical
FT                   protein, similar, but shorter 30 aa in N-terminus, to
FT                   others e.g. Q9RCY9|SCM10.09c from Streptomyces coelicolor
FT                   (256 aa), FASTA scores: opt: 498, E(): 7.8e-24, (47.7%
FT                   identity in 237 aa overlap); BAB50158|MLR3216 from
FT                   Rhizobium loti (291 aa), FASTA scores: opt: 359, E():
FT                   3.7e-15, (33.35% identity in 246 aa overlap); etc.
FT                   Equivalent to AAK47441 from Mycobacterium tuberculosis
FT                   strain CDC1551 (281 aa) but shorter 35 aa."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF2"
FT                   /protein_id="CAD96740.1"
FT                   /translation="MVEAAQRLRYDVFSTTPGFALPAAADTRRDGDRFDEYCDHLLVRD
FT                   DDTGELVGCYRMLAPAGAIAAGGLYTATEFDVCAFDPLRPSLVEMGRAVVREGHRNGGV
FT                   VLLMWAGILAYLDRYGYDYVTGCVSVPIGGDGETPGSRLRGVRDFILNRHAAPPQCQVY
FT                   PYRPVRVDGRSLDDILPPPRPAVPPLMRGYLRLGARACGEPAHDPDFGVGDFCLLLDKD
FT                   HADTRYLRRLRSVAAASEMVNDAR"
FT   CDS             complement(218635..219591)
FT                   /transl_table=11
FT                   /gene="fixB"
FT                   /locus_tag="Mb3054c"
FT                   /standard_name="etfA"
FT                   /product="PROBABLE ELECTRON TRANSFER FLAVOPROTEIN
FT                   (ALPHA-SUBUNIT) FIXB (ALPHA-ETF) (ELECTRON TRANSFER
FT                   FLAVOPROTEIN LARGE SUBUNIT) (ETFLS)"
FT                   /note="Mb3054c, fixB, len: 318 aa. Equivalent to Rv3028c,
FT                   len: 318 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 318 aa overlap). Probable fixB
FT                   (alternate gene name: etfA), electron transfer flavoprotein
FT                   (alpha subunit) for various dehydrogenases. Equivalent to
FT                   O33096|ETFA_MYCLE|FIXB|ML1711|MLCB637.04 ELECTRON TRANSFER
FT                   FLAVOPROTEIN from Mycobacterium leprae (318 aa), FASTA
FT                   scores: opt: 1788, E(): 1.1e-87, (89.3% identity in 318 aa
FT                   overlap). Also highly similar to many e.g. Q9K418|SCG22.27c
FT                   from Streptomyces coelicolor (320 aa), FASTA scores: opt:
FT                   1161, E(): 1.6e-54, (59.45% identity in 323 aa overlap);
FT                   AAK08137|etfa from Rhodobacter sphaeroides (308 aa), FASTA
FT                   scores: opt: 792, E(): 5.1e-35, (45.95% identity in 309 aa
FT                   overlap); P38974|ETFA_PARDE ELECTRON TRANSFER FLAVOPROTEIN
FT                   from Paracoccus denitrificans (307 aa), FASTA scores: opt:
FT                   789, E(): 7.4e-35, (45.95% identity in 309 aa overlap);
FT                   etc. BELONGS TO THE ETF ALPHA-SUBUNIT / FIXB FAMILY."
FT                   /db_xref="GOA:Q7TXF1"
FT                   /db_xref="HSSP:1EFP"
FT                   /db_xref="InterPro:IPR018206"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF1"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96741.1"
FT                   /translation="MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAP
FT                   LVDGLKAAGAAKIYVAESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGR
FT                   LAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGA
FT                   GEQVSVEVPAAAENAARITAREPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALAD
FT                   SLGAAVGASRAAVDSGYYPGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVA
FT                   VNKDEEAPIFEIADYGVVGDLFKVAPQLTEVIKARKG"
FT   CDS             complement(219630..220430)
FT                   /transl_table=11
FT                   /gene="fixA"
FT                   /locus_tag="Mb3055c"
FT                   /standard_name="etfB"
FT                   /product="PROBABLE ELECTRON TRANSFER FLAVOPROTEIN
FT                   (BETA-SUBUNIT) FIXA (BETA-ETF) (ELECTRON TRANSFER
FT                   FLAVOPROTEIN SMALL SUBUNIT) (ETFSS)"
FT                   /note="Mb3055c, fixA, len: 266 aa. Equivalent to Rv3029c,
FT                   len: 266 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 266 aa overlap). Probable fixA
FT                   (alternate gene name: etfB), electron transfer flavoprotein
FT                   (beta-subunit). Equivalent of
FT                   O33095|ETFB_MYCLE|FixA|MLCB637.03 ELECTRON TRANSFER
FT                   FLAVOPROTEIN from Mycobacterium leprae (266 aa), FASTA
FT                   scores: opt: 1603, E(): 7.6e-87, (95.1% identity in 266 aa
FT                   overlap). Also highly similar to others e.g.
FT                   Q9K417|SCG22.28c from Streptomyces coelicolor (262 aa),
FT                   FASTA scores: opt: 860, E(): 2.3e-43, (52.4% identity in
FT                   263 aa overlap); O85691|ETFB_MEGEL from Megasphaera
FT                   elsdenii (270 aa), FASTA scores: opt: 548, E(): 4.2e-25,
FT                   (35.15% identity in 273 aa overlap); etc. Also highly
FT                   similar in particular to Q9KHD0|NONH FLAVOPROTEIN REDUCTASE
FT                   from Streptomyces griseus subsp. griseus (this one is
FT                   required for macrotetrolide biosynthesis in Streptomyces
FT                   griseus) (261 aa), FASTA scores: opt: 867, E(): 8.8e-44,
FT                   (54.0% identity in 263 aa overlap). BELONGS TO THE ETF
FT                   BETA-SUBUNIT / FIXA FAMILY."
FT                   /db_xref="GOA:P64098"
FT                   /db_xref="HSSP:1O95"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64098"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96742.1"
FT                   /translation="MTNIVVLIKQVPDTWSERKLTDGDFTLDREAADAVLDEINERAVE
FT                   EALQIREKEAADGIEGSVTVLTAGPERATEAIRKALSMGADKAVHLKDDGMHGSDVIQT
FT                   GWALARALGTIEGTELVIAGNESTDGVGGAVPAIIAEYLGLPQLTHLRKVSIEGGKITG
FT                   ERETDEGVFTLEATLPAVISVNEKINEPRFPSFKGIMAAKKKEVTVLTLAEIGVESDEV
FT                   GLANAGSTVLASTPKPAKTAGEKVTDEGEGGNQIVQYLVAQKII"
FT   CDS             220661..221485
FT                   /transl_table=11
FT                   /gene="Mb3056"
FT                   /locus_tag="Mb3056"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3056, -, len: 274 aa. Equivalent to Rv3030, len:
FT                   274 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 274 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O33094|MLCB637.02c|ML1713
FT                   hypothetical 30.8 KDa protein from Mycobacterium leprae
FT                   (280 aa), FASTA scores: opt: 1388, E(): 5.5e-83, (78.2%
FT                   identity in 280 aa overlap). N-terminus has similarity to
FT                   hypothetical proteins from a number of organisms and to
FT                   Q54303|EMBL:X86780|RAPM methyltransferase from Streptomyces
FT                   hygroscopicus (317 aa), FASTA scores: opt: 191, E():
FT                   3.6e-05, (35.65% identity in 101 aa overlap)."
FT                   /db_xref="GOA:Q7TXF0"
FT                   /db_xref="InterPro:IPR013216"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXF0"
FT                   /protein_id="CAD96743.1"
FT                   /translation="MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDLDIENYW
FT                   FRRHQVVYQRLAPRCTARDVLEAGCGEGYGADLIACVARQVIAVDYDETAVAHVRSRYP
FT                   RVEVMQANLAELPLPDASVDVVVNFQVIEHLWDQARFVRECARVLRGSGLLMVSTPNRI
FT                   TFSPGRDTPINPFHTRELNADELTSLLIDAGFVDVAMCGLFHGPRLRDMDARHGGSIID
FT                   AQIMRAVAGAPWPPELAADVAAVTTADFEMVAAGHDRDIDDSLDLIAIAVRP"
FT   CDS             221482..223062
FT                   /transl_table=11
FT                   /gene="Mb3057"
FT                   /locus_tag="Mb3057"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3057, -, len: 526 aa. Equivalent to Rv3031, len:
FT                   526 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 526 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBR4|ML1714 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (522 aa), FASTA scores: opt:
FT                   3167, E(): 4.4e-190, (86.15% identity in 526 aa overlap);
FT                   and highly similar to truncated O33093|MLCB637.01c
FT                   HYPOTHETICAL 37.2 KDA PROTEIN (FRAGMENT) from Mycobacterium
FT                   leprae (338 aa), FASTA scores: opt: 2041, E(): 5.7e-120,
FT                   (84.8% identity in 342 aa overlap). Also some similarity to
FT                   hypothetical proteins Q9V0M7|PAB1857 from Pyrococcus abyssi
FT                   (602 aa), FASTA scores: opt: 477, E(): 3.5e-22, (31.2%
FT                   identity in 556 aa overlap); and Synechocystis
FT                   P74630|D90916|SLL0735 from Synechocystis sp. strain PCC
FT                   6803 (529 aa), FASTA scores: opt: 282, E(): 4.7e-10, (28.6%
FT                   identity in 560 aa overlap)."
FT                   /db_xref="GOA:Q7TXE9"
FT                   /db_xref="InterPro:IPR015293"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE9"
FT                   /protein_id="CAD96744.1"
FT                   /translation="MNTSASPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWAAAYL
FT                   PLLQVLAALADENRHRLITLGMTPVVNAQLDDPYCLNGVHHWLANWQLRAEEAASVRYA
FT                   RQSKSADYPSCTPEALRAFGIRECADAARALDNFATRWRHGGSPLLRGLIDAGTVELLG
FT                   GPLAHPFQPLLAPRLREFALREGLADAQLRLAHRPKGIWAPECAYAPGMEVDYATAGVS
FT                   HFMVDGPSLHGDTALGRPVGKTDVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHL
FT                   TGLKPARVTGRNVPSEQKAPYDPERADRAVDVHVADFVDVVRNRLLSESERIGRPAHVI
FT                   AAFDTELFGHWWYEGPTWLQRVLRALPAAGVRVGTLSDAIADGFVGDPVELPPSSWGSG
FT                   KDWQVWSGAKVADLVQLNSEVVDTALTTIDKALAQTASLDGPLPRDHVADQILRETLLT
FT                   VSSDWPFMVSKDSAADYARYRAHLHAHATREIAGALAAGRRDTARRLAEGWNRADGLFG
FT                   ALDARRLPK"
FT   CDS             223094..224338
FT                   /transl_table=11
FT                   /gene="Mb3058"
FT                   /locus_tag="Mb3058"
FT                   /product="POSSIBLE TRANSFERASE"
FT                   /EC_number="2.-.-.-"
FT                   /note="Mb3058, -, len: 414 aa. Equivalent to Rv3032, len:
FT                   414 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 414 aa overlap). Possible transferase
FT                   (EC 2.-.-.-), equivalent to Q9CBR3|ML1715 PUTATIVE
FT                   TRANSFERASE from Mycobacterium leprae (438 aa), FASTA
FT                   scores: opt: 2456, E(): 7.3e-145, (87.9% identity in 414 aa
FT                   overlap). Also similar to hypothetical proteins and various
FT                   transferases e.g. P73369|SLL1971 HYPOTHETICAL 46.2 KDA
FT                   PROTEIN from Synechocystis sp. strain PCC 6803 (404 aa),
FT                   FASTA scores: opt: 584, E(): 7.3e-29, (34.5% identity in
FT                   400 aa overlap); Q9Z5B7|SC2G5.06 PUTATIVE TRANSFERASE from
FT                   Streptomyces coelicolor (406 aa), FASTA scores: opt: 509,
FT                   E(): 3.3e-24, (35.9% identity in 413 aa overlap);
FT                   Q9UZA1|PAB0827 GALACTOSYLTRANSFERASE (LPS BIOSYNTHESIS RFBU
FT                   RELATED PROTEIN) from Pyrococcus abyssi (371 aa), FASTA
FT                   scores: opt: 381, E(): 2.6e-16, (26.75% identity in 404 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:Q7TXE8"
FT                   /db_xref="InterPro:IPR001296"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE8"
FT                   /protein_id="CAD96745.1"
FT                   /translation="MRILMVSWEYPPVVIGGLGRHVHHLSTALAAAGHDVVVLSRCPSG
FT                   TDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLRLKKLGTDR
FT                   SWRPDVVHAHDWLVAHPAIALAQFYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESW
FT                   LVRESDSLITCSASMNDEITELFGPGLAEITVIRNGIDAARWPFAARRPRTGPAELLYV
FT                   GRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATRFVGHL
FT                   DHTELLALLHRADAAVLPSHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSC
FT                   APRDVAGLAAAVRSVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQ
FT                   PQPRLPIVEHALPDR"
FT   CDS             224940..225488
FT                   /transl_table=11
FT                   /gene="Mb3059"
FT                   /locus_tag="Mb3059"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb3059, -, len: 182 aa. Equivalent to Rv3033, len:
FT                   182 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 182 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE7"
FT                   /protein_id="CAD96746.1"
FT                   /translation="MAHSIVRTLLASGAATALIAIPTACSFSIGTSHSHSVSKAEVARQ
FT                   ITAKMTDAAGNKPESVTCPSDLPAEVGAELNCEMKIKDRTFNVNVTVTSVDGSDVKFDM
FT                   VETVDKNQVANIISDKLFQRVGARPDSVTCPDNLKGVEGAKLRCRLTDGSKTYGISVIV
FT                   TSVDAGDVNFDFKVDDHPE"
FT   CDS             complement(225579..226481)
FT                   /transl_table=11
FT                   /gene="Mb3060c"
FT                   /locus_tag="Mb3060c"
FT                   /product="POSSIBLE TRANSFERASE"
FT                   /EC_number="2.-.-.-"
FT                   /note="Mb3060c, -, len: 300 aa. Equivalent to Rv3034c, len:
FT                   300 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 300 aa overlap). Possible transferase
FT                   (2.-.-.-), equivalent to AAK47449|MT3119 Hexapeptide
FT                   transferase family protein from Mycobacterium tuberculosis
FT                   strain CDC1551 but N-terminus shorter 39 residues (262 aa),
FT                   FASTA scores: opt: 1773, E(): 4.7e-105, (100.0% identity in
FT                   262 aa overlap). Similar to Q9CBR1|ML1719 from
FT                   Mycobacterium leprae but also shorter in N-terminus (245
FT                   aa), FASTA scores: opt: 1549, E(): 6.6e-91, (90.6% identity
FT                   in 244 aa overlap). Some weakly similarity with other
FT                   transferases (C-terminal part shows some similarity to
FT                   acetyltransferase from Methanococcus jannaschii (214 aa)).
FT                   Alternative start possible at 3395077 but codon usage not
FT                   as good."
FT                   /db_xref="GOA:Q7TXE6"
FT                   /db_xref="InterPro:IPR001451"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE6"
FT                   /protein_id="CAD96747.1"
FT                   /translation="MNVLSLGSSSGVVWGRVPITAPAGAATGVTSRADAHSQMRRYAQT
FT                   GPTAKLSSAPMTTMWGAPLHRRWRGSRLRDPRQAKFLTLASLKWVLANRAYTPWYLVRY
FT                   WRLLRFKLANPHIITRGMVFLGKGVEIHATPELAQLEIGRWVHIGDKNTIRAHEGSLRF
FT                   GDKVVLGRDNVINTYLDIEIGDSVLMADWCYICDFDHRMDDITLPIKDQGIIKSPVRIG
FT                   PDTWIGVKVSVLRGTTIGRGCVLGSHAVVRGAIPDYSIAVGAPAKVVKNRQLSWEASAA
FT                   QRAELAAALADIERKKAAR"
FT   CDS             226939..228021
FT                   /transl_table=11
FT                   /gene="Mb3061"
FT                   /locus_tag="Mb3061"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3061, -, len: 360 aa. Equivalent to Rv3035, len:
FT                   360 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 360 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBR0|ML1720 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (364 aa), FASTA scores: opt:
FT                   1963, E(): 1.4e-108, (75.8% identity in 363 aa overlap)."
FT                   /db_xref="InterPro:IPR002372"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE5"
FT                   /protein_id="CAD96748.1"
FT                   /translation="MAAGPALSARGYLALNGQTPAGCSLMEWQNDNNGRQRWCVRLVQG
FT                   GGFAGPLFDGFDNLYVGQPGAIISFPPTQWTRWRQPVIGMPSTPRFLGHGRLLVSTHLG
FT                   QLLVFDTRRGMVVGSPVDLVDGIDPTDATRGLADCAPARPGCPVAAAPAFSSVNGTVVV
FT                   SVWQPGEPAAKLVGLKYHAEQLVREWTSDAVSAGVLASPVLSADGSTVYVNGRDHRLWA
FT                   LNAADGKAKWSAPLGFLAQTPPALTPHGLIVSGGGPDTALAAFRDAGDHAEGAWRRDDV
FT                   TALSTASLAGTGVGYTVISGPNHDGTPGLSLLVFDPANGHTVNSYPLPGATGYPVGVSV
FT                   GNDRRVVTATSDGQVYSFAP"
FT   CDS             complement(228018..228701)
FT                   /transl_table=11
FT                   /gene="TB22.2"
FT                   /locus_tag="Mb3062c"
FT                   /product="PROBABLE CONSERVED SECRETED PROTEIN TB22.2"
FT                   /note="Mb3062c, TB22.2, len: 227 aa. Equivalent to Rv3036c,
FT                   len: 227 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 227 aa overlap). Probable TB22.2,
FT                   conserved secreted protein, with putative N-terminal signal
FT                   peptide, highly similar to secreted immunogenic protein
FT                   MPT64/MPB64 P19996|Rv1980c|MTCY39.39 from Mycobacterium
FT                   tuberculosis and Mycobacterium bovis (228 aa), FASTA
FT                   scores: opt: 681, E(): 2.5e-35, (45.8% identity in 227 aa
FT                   overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD96749.1"
FT                   /translation="MRYLIATAVLVAVVLVGWPAAGAPPSCAGLGGTVQAGQICHVHAS
FT                   GPKYMLDMTFPVDYPDQRALTDYITQNRDGFVNVAQGSPLRDQPYQMDATSEQHSSGQP
FT                   PQATRSVVLKFFQDLGGAHPSTWYKAFNYNLATSQPITFDTLFVPGTTPLDSIYPIVQR
FT                   ELARQTGFGAAILPSTGLDPAHYQNFAITDDSLIFYFAQGELLPSFVGACQAQVPRSAI
FT                   PPLAI"
FT   CDS             complement(228774..229850)
FT                   /transl_table=11
FT                   /gene="Mb3063c"
FT                   /locus_tag="Mb3063c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb3063c, -, len: 358 aa. Equivalent to Rv3037c, len:
FT                   358 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 358 aa overlap). Conserved hypothetical
FT                   protein, similar in part to others e.g. O86799|SC6G4.36c
FT                   from Streptomyces coelicolor (426 aa), FASTA scores: opt:
FT                   545, E(): 5.5e-27, (36.15% identity in 354 aa overlap);
FT                   Q9UZW6|PAB0687 from Pyrococcus abyssi (386 aa), FASTA
FT                   scores: opt: 262, E(): 3.5e-09, (31.0% identity in 200 aa
FT                   overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TXE3"
FT                   /protein_id="