EBI Dbfetch

ID   BX248342; SV 1; linear; genomic DNA; STD; PRO; 306550 BP.
XX
AC   BX248342;
XX
DT   10-JUN-2003 (Rel. 76, Created)
DT   23-OCT-2008 (Rel. 97, Last updated, Version 5)
XX
DE   Mycobacterium bovis subsp. bovis AF2122/97 complete genome; segment 9/14
XX
KW   complete genome.
XX
OS   Mycobacterium bovis AF2122/97
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Mycobacteriaceae; Mycobacterium;
OC   Mycobacterium tuberculosis complex.
XX
RN   [1]
RX   DOI; 10.1073/pnas.1130426100
RX   PUBMED; 12788972.
RA   Garnier T., Eiglmeier K., Camus J.C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis";
RL   Proc. Natl. Acad. Sci. U.S.A. 100(13):7877-7882(2003).
XX
RN   [2]
RP   1-306550
RA   Garnier T.;
RT   ;
RL   Submitted (24-MAR-2003) to the EMBL/GenBank/DDBJ databases.
RL   Garnier T., Unite de Genetique Moleculaire Bacterienne Institut Pasteur
RL   28,rue du Dr Roux 75724 PARIS cedex 15, France. e-mail:tgarnier@pasteur.fr
RL   Submitted on behalf of the Mycobacterium bovis sequencing teams, TB
RL   Research Group, Veterinary Laboratories Agency Weybridge, Woodham Lane, New
RL   Haw,Addlestone, Surrey KT15 3NB, UK. Sanger Centre, Wellcome Trust Genome
RL   Campus, Hinxton,Cambridge CB10 1SA, UK. PT4 Annotation, Genopole, Institut
RL   Pasteur, 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France. Unite de
RL   Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur
RL   Roux, 75724 Paris Cedex 15, France.
XX
DR   EMBL-CON; BX248333.
DR   RFAM; RF00005; tRNA.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..306550
FT                   /organism="Mycobacterium bovis AF2122/97"
FT                   /strain="AF2122/97"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:233413"
FT   CDS             201..1286
FT                   /transl_table=11
FT                   /gene="adhE2"
FT                   /locus_tag="Mb2283"
FT                   /product="Probable zinc-dependent alcohol dehydrogenase
FT                   AdhE2"
FT                   /EC_number="1.2.1.-"
FT                   /note="Mb2283, adhE2, len: 361 aa. Equivalent to Rv2259,
FT                   len: 361 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 361 aa overlap). Probable adhE2,
FT                   zinc-containing alcohol dehydrogenase, similar to several,
FT                   especially mycothiol-dependent formaldehyde dehydrogenase
FT                   from Amycolatopsis methanolica P80094 (360 aa). Contains
FT                   PS00059 Zinc-containing alcohol dehydrogenases signature.
FT                   FASTA scores: >sp|P80094|FADH_AMYME NAD/MYCOTHIOL-DEPENDENT
FT                   FORMALDEHYDE DEHYDROGENASE (MD-FALDH) Length = 360, Expect
FT                   = e-156, Identities = 268/358 (74%). Also similar to
FT                   Rv0162c, (MTCI28.02c, 35.0% identity in 371 aa overlap)."
FT                   /db_xref="GOA:Q7VEM6"
FT                   /db_xref="HSSP:1F8F"
FT                   /db_xref="InterPro:IPR013154"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM6"
FT                   /protein_id="CAD97144.1"
FT                   /translation="MSQTVRGVIARQKGEPVELVNIVVPDPGPGEAVVDVTACGVCHTD
FT                   LTYREGGINDEYPFLLGHEAAGIIEAVGPGVTAVEPGDFVILNWRAVCGQCRACKRGRP
FT                   RYCFDTFNAEQKMTLTDGTELTAALGIGAFADKTLVHSGQCTKVDPAADPAVAGLLGCG
FT                   VMAGLGAAINTGGVTRDDTVAVIGCGGVGDAAIAGAALVGAKRIIAVDTDDTKLDWART
FT                   FGATHTVNAREVDVVQAIGGLTDGFGADVVIDAVGRPETYQQAFYARDLAGTVVLVGVP
FT                   TPDMRLDMPLVDFFSHGGALKSSWYGDCLPESDFPTLIDLYLQGRLPLQRFVSERIGLE
FT                   DVEEAFHKMHGGKVLRSVVML"
FT   CDS             1286..1921
FT                   /transl_table=11
FT                   /gene="Mb2284"
FT                   /locus_tag="Mb2284"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2284, -, len: 211 aa. Equivalent to Rv2260, len:
FT                   211 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 211 aa overlap). Conserved hypothetical
FT                   protein, similar to hypothetical proteins Rv0634c, Rv1637c,
FT                   Rv3677c, Rv2581c from Mycobacterium tuberculosis and to
FT                   various hydrolases. FASTA scores: sptr|O06154|O06154
FT                   HYPOTHETICAL 21.3 KD PROTEIN (200 aa) opt: 355, E(): 4e-
FT                   15; (37.4% identity in 198 aa overlap)."
FT                   /db_xref="GOA:Q7TYW0"
FT                   /db_xref="InterPro:IPR001279"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYW0"
FT                   /protein_id="CAD97145.1"
FT                   /translation="MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAA
FT                   PIIDAVGGRKVVAVICTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWRMTHPDKSFRA
FT                   VSDGDAVRVGGTELRALHTPGHSPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSY
FT                   SDFPTILRSISGRLGALPGDTVVHTGHGDSTTIGDEIVHYEEWVARGH"
FT   CDS             complement(1998..3506)
FT                   /transl_table=11
FT                   /gene="Mb2285c"
FT                   /locus_tag="Mb2285c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2285c, -, len: 502 aa. Equivalent to Rv2262c and
FT                   Rv2261c, len: 360 aa and 140 aa, from Mycobacterium
FT                   tuberculosis strain H37Rv, (94.7% identity in 357 aa
FT                   overlap and 100.0% identity in 140 aa overlap). Conserved
FT                   hypothetical protein, with function unknown but some
FT                   similarity to N-terminal 70% of
FT                   P23930|P77703|LNT_ECOLI|CUTE|B0657 APOLIPOPROTEIN
FT                   N-ACYLTRANSFERASE (EC 2.3.1.-) from Escherichia coli strain
FT                   K12 (512 aa), FASTA scores: opt: 239, E(): 1.6e-07, (30.4%
FT                   identity in 359 aa overlap). Note that neighboring ORF
FT                   shows similarity to N -terminal part of PCC6803
FT                   apolipoprotein N-acyltransferase from Synechocystis sp.,
FT                   suggesting possibility of frameshift. Sequence of clones
FT                   from two sources has been checked but no error found.
FT                   Appear to be two extra bases at position 1876970 compared
FT                   to CDC1551 strain. Conserved hypothetical protein, with
FT                   function unknown but some similarity to C-terminal end of
FT                   PCC6803 apolipoprotein N-acyltransferase from Synechocystis
FT                   sp. Note that next ORF shows similarity to N-terminal part
FT                   of P74055 APOLIPOPROTEIN N-ACYLTRANSFERASE from Escherichia
FT                   coli (519 aa), FASTA scores: opt: 142, E(): 0.007, (29.9%
FT                   identity in 117 aa overlap), suggesting possible
FT                   frameshift. Sequence of clones from two sources has been
FT                   checked but no error found. REMARK-M.bovis-M.tuberculosis:
FT                   In Mycobacterium tuberculosis strain H37Rv, Rv2262c and
FT                   Rv2261c exist as 2 genes. In Mycobacterium bovis, a 2 bp
FT                   deletion (ct-*) results in a single product which is more
FT                   similar to Rv2262c."
FT                   /db_xref="GOA:Q7TYV9"
FT                   /db_xref="InterPro:IPR003010"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV9"
FT                   /protein_id="CAD97146.1"
FT                   /translation="MALRAGARRQPVIGCAAALVFGGLPALAFPAPSWWWLAWFGLVPL
FT                   LLVVRAAPTSWEGALRAWTGMGGFVLATQYWLVTSAGPMLVLLAAGLGVLWLPAGWLAH
FT                   RLLSVPVTTCRVGAALVVVPSAWVAAEAVRSWQSLGGPWALLGASQWSQPVTLASASLG
FT                   GVWLTSFLLVATNTAIASVLVCRATGGRLVALGCVIGCAGLGPASYLLGSVPVGGPTVR
FT                   VALVQAGDIADAAARLAAGEEFTAAVADQRPDLVVWGESSVGQDLTRHPDVLARLAELS
FT                   QRVGADLLVNVDAPAPDGGIYKSAVLVGAHEAVGSYRKTRLVPFGEYVPLRPLFGWITR
FT                   YSKAAAKDRQRGAGPVVLAVNSLHIAPLISYEMTFSDLTRHAARLGAALLVYQSSTSTF
FT                   QGSWAQPQLAAQPAVRAVEAGIPAVHASLSGDSSAFDTRGRRLAWCSAEFNGAIVVNVP
FT                   LASNVTLYLRLGDWVPVTAFVVMGAGFAVFLRRSLARVSDCADK"
FT   CDS             3595..4548
FT                   /transl_table=11
FT                   /gene="Mb2286"
FT                   /locus_tag="Mb2286"
FT                   /product="Possible oxidoreductase"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2286, -, len: 317 aa. Equivalent to Rv2263, len:
FT                   317 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 317 aa overlap). Possible
FT                   oxidoreductase (EC 1.-.-.-), similar to several
FT                   oxidoreductases. Similarity suggests alternative GTG start
FT                   at 10154 but then no rbs. FASTA scores: sptr|Q544 05|Q54405
FT                   PROBABLY AN NADP-DEPENDENT OXIDOREDUCTASE (297 aa) opt:
FT                   487, E(): 1.1e-23; (36.1% identity in 299 aa overlap). Also
FT                   similar to M. tuberculosis Rv0068, and Rv0439c."
FT                   /db_xref="GOA:Q7VEM5"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM5"
FT                   /protein_id="CAD97147.1"
FT                   /translation="MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAI
FT                   RNRAKGEAAVEEIRTAVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVM
FT                   TPPERVTTADGFELQFGSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDD
FT                   LQFERSYAPMTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSH
FT                   GRDKPALMERLYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGG
FT                   GVREAKVPAAARNDADSKRLWEVSEQLTGVSYPKSR"
FT   CDS             complement(4526..6304)
FT                   /transl_table=11
FT                   /gene="Mb2287c"
FT                   /locus_tag="Mb2287c"
FT                   /product="conserved hypothetical proline rich protein"
FT                   /note="Mb2287c, -, len: 592 aa. Equivalent to Rv2264c, len:
FT                   592 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 592 aa overlap). Conserved hypothetical
FT                   Pro-rich protein, similar to hypothetical proteins Rv0312
FT                   (MTCY63.17, 620 aa and Rv0350) that has highly Pro-,
FT                   Thr-rich C-terminus. Contains PS00343 Gram-positive cocci
FT                   surface proteins 'anchoring' hexapeptide. FASTA scores:
FT                   Z96800|MTCY63_17 Mycobacterium tuberculosis cosmid (620 aa)
FT                   opt: 1075, E(): 8.8e-24; (38.9% identity in 627 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7VEM4"
FT                   /db_xref="InterPro:IPR001023"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM4"
FT                   /protein_id="CAD97148.1"
FT                   /translation="MATGARPALGLSIGVTNLAAVAADHSITRKPVLTLYRQRPPEVGV
FT                   PSENPRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTATGGRALP
FT                   GSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLLPDAAAALYAIRADPGI
FT                   PARGIVAVCDFGGSGTGITLVDAADEYRPVAATVRHQAFSGDLIDQSLLSYVMSELPGT
FT                   GAFDPAGTSAIGSLTKLRIECRKAKERLSSSTVTTLTDALGGDIRLTRNELEDTIRDSL
FT                   DSVGRALEQTLARSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAA
FT                   FGGALWAARRPGDTSATVLTAVTSATATAPADAPASVLQPALAWSEADEDSHIGPAPGY
FT                   TAARPSLSFDHDAHAEPEPKSPPIPWYRLPAVIITGTTVAVLLVGAAVAIGLSTGDQPT
FT                   APGTPQRPGVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGPAPPLQQPLPPPPTTTN
FT                   TQPAVTTDVITPAPTTPASAPPATTQPPATTQPPATTSPSPPPIPPIPPIPEIPQLPPG
FT                   IPQVPGIGQFSAISGS"
FT   CDS             6654..7883
FT                   /transl_table=11
FT                   /gene="Mb2288"
FT                   /locus_tag="Mb2288"
FT                   /product="Possible conserved integral membrane protein"
FT                   /note="Mb2288, -, len: 409 aa. Equivalent to Rv2265, len:
FT                   409 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 409 aa overlap). Possible conserved
FT                   integral membrane protein, with some similarity to others
FT                   e.g. M. thermoauto. sp|O26855|O26855 CONSERVED PROTEIN (383
FT                   aa), FASTA score: opt: 898 z-score: 1023.5 E(): 0; 38.0%
FT                   identity in 384 aa overlap; Q58713 HYPOTHETICAL 44.1 KD
FT                   PROTEIN 1 317 (398 aa), FASTA scores, opt: 305 E():
FT                   1.2e-11; 22.8% identity in 382 aa overlap; also KGTP_ECOLI
FT                   P17448 alpha-ketoglutarate permease (432 aa), FASTA scores,
FT                   opt: 156, E(): 0.006, (24.8% identity in 416 aa overlap)"
FT                   /db_xref="GOA:P64962"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64962"
FT                   /protein_id="CAD97149.1"
FT                   /translation="MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSI
FT                   TGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVP
FT                   LLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGAMI
FT                   GPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSA
FT                   PRPWALPAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALT
FT                   ALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGV
FT                   VADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMF
FT                   AIRLPRVAPS"
FT   CDS             8058..9344
FT                   /transl_table=11
FT                   /gene="cyp124"
FT                   /locus_tag="Mb2289"
FT                   /product="Probable cytochrome P450 124 CYP124"
FT                   /EC_number="1.14.-.-"
FT                   /note="Mb2289, cyp124, len: 428 aa. Equivalent to Rv2266,
FT                   len: 428 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 428 aa overlap). Probable cyp124,
FT                   cytochrome P450 (EC 1.14.-.-), similar to e.g. G405543
FT                   cytochrome P450 (406 aa), FASTA scores, opt: 763,E(): 0,
FT                   (35.4% identity in 393 aa overlap), similar to e.g.
FT                   MTCY50.26, 33.8% identity in 370 aa overlap"
FT                   /db_xref="GOA:P0A517"
FT                   /db_xref="HSSP:1CPT"
FT                   /db_xref="InterPro:IPR017972"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A517"
FT                   /protein_id="CAD97150.1"
FT                   /translation="MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFAT
FT                   LRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELA
FT                   EYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADL
FT                   VSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAY
FT                   ATALAEDRRVNHHDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVL
FT                   ALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMAAGDKVS
FT                   LWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQ
FT                   MPDVVATEEPARLLSQFIHGIKTLPVTWS"
FT   CDS             complement(9598..10764)
FT                   /transl_table=11
FT                   /gene="Mb2290c"
FT                   /locus_tag="Mb2290c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2290c, -, len: 388 aa. Equivalent to Rv2267c, len:
FT                   388 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 388 aa overlap). Conserved hypothetical
FT                   protein; some similarity to Mycobacterium tuberculosis
FT                   Rv3529c; gp|Z82098|MTCY3C7_27 (384 aa) FASTA score: opt:
FT                   261, E(): 3.6e-10; 27.3% identity in 253 aa overlap"
FT                   /db_xref="GOA:P64964"
FT                   /db_xref="InterPro:IPR000863"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64964"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97151.1"
FT                   /translation="MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRW
FT                   HFAVLYTFLSMVNSCLGLWQKIVFGRRVAETVIADPPIFIVGHWRTGTTLLHELLVVDD
FT                   RHTGPTGYECLAPHHFLLTEWFAPYVEFLVSKHRAMDNMDLSLHHPQEDEFVWCMQGLP
FT                   SPYLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRRRKTVILKNPTHS
FT                   FRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKALYRIHGLQQPTFDGLDDKVVSTYV
FT                   DLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLAD
FT                   HADYKTNSYQLTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG"
FT   CDS             complement(10761..12230)
FT                   /transl_table=11
FT                   /gene="cyp128"
FT                   /locus_tag="Mb2291c"
FT                   /product="PROBABLE CYTOCHROME P450 128 CYP128"
FT                   /EC_number="1.14.-.-"
FT                   /note="Mb2291c, cyp128, len: 489 aa. Equivalent to Rv2268c,
FT                   len: 489 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 489 aa overlap). Probable cyp128,
FT                   cytochrome P450 (EC 1.14.-.-), similar to (but longer than)
FT                   cytochrome p-450 e.g. CPXK_SACER P3 3271 cytochrome p-450
FT                   107b1 (405 aa), FASTA scores, opt: 620, E(): 8.3e-33,
FT                   (31.8% identity in 406 aa overlap); contains PS00086
FT                   Cytochrome P450 cysteine heme-iron ligand signature,
FT                   similar to MTCY50.26, 32.7% identity in 382 aa overlap"
FT                   /db_xref="GOA:P63714"
FT                   /db_xref="HSSP:1IO7"
FT                   /db_xref="InterPro:IPR017972"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63714"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97152.1"
FT                   /translation="MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRR
FT                   RASSGGIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLTDFDP
FT                   FDPAIAADPYPHYRELLAGERVQYNPKRDVYILSRYADVREAARNHDTLSSARGVTFSR
FT                   GWLPFLPTSDPPAHTRMRKQLAPGMARGALETWRPMVDQLARELVGGLLTQTPADVVST
FT                   VAAPMPMRAITSVLGVDGPDEAAFCRLSNQAVRITDVALSASGLISLVQGFAGFRRLRA
FT                   LFTHRRDNGLLRECTVLGKLATHAEQGRLSDDELFFFAVLLLVAGYESTAHMISTLFLT
FT                   LADYPDQLTLLAQQPDLIPSAIEEHLRFISPIQNICRTTRVDYSVGQAVIPAGSLVLLA
FT                   WGAANRDPRQYEDPDVFRADRNPVGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDR
FT                   IEVVEPPTWTTNANLRGLTRLRVAVTPRVAP"
FT   CDS             complement(12243..12575)
FT                   /transl_table=11
FT                   /gene="Mb2292c"
FT                   /locus_tag="Mb2292c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2292c, -, len: 110 aa. Equivalent to Rv2269c, len:
FT                   110 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 110 aa overlap). Unknown protein."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64966"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97153.1"
FT                   /translation="MANDARPLARLANCRVGDQSSATHAYTVGPVLGVPPTGGVDLRYG
FT                   GRAGIGRSETVTDHGAVGRRYHQPCAGQIRLSELRVTILLRCETLCETAQLLRCPPLPC
FT                   DCSTPL"
FT   CDS             12652..13179
FT                   /transl_table=11
FT                   /gene="lppN"
FT                   /locus_tag="Mb2293"
FT                   /product="Probable lipoprotein lppN"
FT                   /note="Mb2293, lppN, len: 175 aa. Equivalent to Rv2270,
FT                   len: 175 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.4% identity in 175 aa overlap). Probable lppN,
FT                   lipoprotein; has appropriately positioned prokaryotic
FT                   membrane lipoprotein attachment site PS00013."
FT                   /db_xref="GOA:Q7VEM3"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7VEM3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97154.1"
FT                   /translation="MRLPGRHVLYALSAVTMLAACSSNGARGGIASTNMNPTNPPATAE
FT                   TATVSPTPAPQSARTETWINLQVGDCLADLPPADLSRITVTIVDCATAHSAEVYLRAPV
FT                   AVDAAVVSMANRDCAAGFAPYTGQSVDTSPYSVAYLIDSHQDRTGADLTPSTVICLLQP
FT                   ANGQLLTGSARR"
FT   CDS             13286..13585
FT                   /transl_table=11
FT                   /gene="Mb2294"
FT                   /locus_tag="Mb2294"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2294, -, len: 99 aa. Equivalent to Rv2271, len: 99
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 99 aa overlap). Conserved hypothetical protein;
FT                   some similarity to hypothetical protein
FT                   AAK01340.1|AF265275_3 (AF265275) from uncultured organism
FT                   Pu8 (104 aa) E= 4e-10, (34% identity in 91 aa overlap)"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64968"
FT                   /protein_id="CAD97155.1"
FT                   /translation="MTTPPDKARRRFLRDAYKNAERVARTALLTIDQDQLEQLLDYVDE
FT                   RLGEQPCDHTARHAQRWAQSHRIEWETLAEGLQEFGGYCDCEIVMNVEPEAIFG"
FT   CDS             13691..14059
FT                   /transl_table=11
FT                   /gene="Mb2295"
FT                   /locus_tag="Mb2295"
FT                   /product="PROBABLE CONSERVED MEMBRANE PROTEIN"
FT                   /note="Mb2295, -, len: 122 aa. Equivalent to Rv2272, len:
FT                   122 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 122 aa overlap). Probable conserved
FT                   transmembrane PROTEIN, similar to YIDH_ECOLI P31445
FT                   hypothetical 12.8 kd protein (115 aa), FASTA scores, opt:
FT                   291, E(): 2.9e-14, (45.6% identity in 103 aa overlap),
FT                   similar to MTCY339.37c, (35.0% identity in 100 aa
FT                   overlap)."
FT                   /db_xref="GOA:P64970"
FT                   /db_xref="InterPro:IPR003807"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64970"
FT                   /protein_id="CAD97156.1"
FT                   /translation="MADDSNDTATDVEPDYRFTLANERTFLAWQRTALGLLAAAVALVQ
FT                   LVPELTIPGARQVLGVVLAILAILTSGMGLLRWQQADRAMRRHLPLPRHPTPGYLAVGL
FT                   CVVGVVALALVVAKAITG"
FT   CDS             14056..14385
FT                   /transl_table=11
FT                   /gene="Mb2296"
FT                   /locus_tag="Mb2296"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2296, -, len: 109 aa. Equivalent to Rv2273, len:
FT                   109 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 109 aa overlap). Probable conserved
FT                   transmembrane protein, similar to Rv2272 (MTCY339.38c),
FT                   (35.0% identity in 100 aa overlap)."
FT                   /db_xref="GOA:P64972"
FT                   /db_xref="InterPro:IPR003807"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64972"
FT                   /protein_id="CAD97157.1"
FT                   /translation="MNRHSTAASDRGLQAERTTLAWTRTAFALLVNGVLLTLKDTQGAD
FT                   GPAGLIPAGLAGAAASCCYVIALQRQRALSHRPLPARITPRGQVHILATAVLVLMVVTA
FT                   FAQLL"
FT   CDS             complement(14442..14759)
FT                   /transl_table=11
FT                   /gene="Mb2297c"
FT                   /locus_tag="Mb2297c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2297c, -, len: 105 aa. Equivalent to Rv2274c, len:
FT                   105 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.0% identity in 105 aa overlap). Unknown protein;
FT                   questionable ORF"
FT                   /db_xref="InterPro:IPR013032"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV8"
FT                   /protein_id="CAD97158.1"
FT                   /translation="MSIARSAQPIGWISCPPKGGSSCCRCGGGYTHMFCVSAWTGLVVD
FT                   LQAEQVRSVVTERLRRRIGRGAPILAGTLAPGVGLAAQNREFRQFTGRSAPPSATIAFG
FT                   E"
FT   CDS             14837..15706
FT                   /transl_table=11
FT                   /gene="Mb2298"
FT                   /locus_tag="Mb2298"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2298, -, len: 289 aa. Equivalent to Rv2275, len:
FT                   289 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 289 aa overlap). Conserved hypothetical
FT                   protein. Some similarity to Bacillus subtilis
FT                   sp|O34351|O34351 YVMC (248 aa), FASTA score: opt: 280, E():
FT                   2.7e -11; 28.2% identity in 227 aa overlap"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97159.1"
FT                   /translation="MSYVAAEPGVLISPTDDLQSPRSAPAAHDENADGITGGTRDDSAP
FT                   NSRFQLGRRIPEATAQEGFLVRPFTQQCQIIHTEGDHAVIGVSPGNSYFSRQRLRDLGL
FT                   WGLTNFDRVDFVYTDVHVAESYEALGDSAIEARRKAVKNIRGVRAKITTTVNELDPAGA
FT                   RLCVRPMSEFQSNEAYRELHADLLTRLKDDEDLRAVCQDLVRRFLSTKVGPRQGATATQ
FT                   EQVCMDYICAEAPLFLDTPAILGVPSSLNCYHQSLPLAEMLYARGSGLRASRNQGHAIV
FT                   TPDGSPAE"
FT   CDS             15703..16893
FT                   /transl_table=11
FT                   /gene="cyp121"
FT                   /locus_tag="Mb2299"
FT                   /product="Cytochrome P450 121 CYP121"
FT                   /EC_number="1.14.-.-"
FT                   /note="Mb2299, cyp121, len: 396 aa. Equivalent to Rv2276,
FT                   len: 396 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 396 aa overlap). cyp121, cytochrome
FT                   P450 (EC 1.14.-.-) (see citation below), similar to e.g.
FT                   G303644 (397 aa) opt: 675, z-score: 776.4, E(): 2.7e-36,
FT                   (33.7% identity in 407 aa overlap); contains PS00086
FT                   Cytochrome P450 cysteine heme-iron ligand signature,
FT                   similar to MTCY339.42, 29.2% identity in 298 aa overlap."
FT                   /db_xref="GOA:P0A515"
FT                   /db_xref="InterPro:IPR017972"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A515"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97160.1"
FT                   /translation="MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLV
FT                   SSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITP
FT                   KAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRS
FT                   LSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDEL
FT                   FATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFA
FT                   DGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGR
FT                   GQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW"
FT   CDS             complement(17078..17977)
FT                   /transl_table=11
FT                   /gene="Mb2300c"
FT                   /locus_tag="Mb2300c"
FT                   /product="Possible glycerolphosphodiesterase"
FT                   /note="Mb2300c, -, len: 299 aa. Equivalent to Rv2277c, len:
FT                   301 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.661% identity in 295 aa overlap). Possible
FT                   glycerolphosphodiesterase, similar to e.g. UGPQ_ECOLI
FT                   P10908 glycerophosphoryldiester phosphodiesterase
FT                   (cytosolic) (247 aa), FASTA scores, opt: 149, E(): 0.0061,
FT                   (27.2% identity in 195 aa overlap). Start of protein
FT                   uncertain, encoded by neighbouring IS6110 as given, is
FT                   intact in Mycobacterium tuberculosis CDC1551.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
FT                   1358 bp deletion containing an IS6110 sequence prior to the
FT                   start of Mb2300c disrupts the 5' start of Rv2277c resulting
FT                   in a slightly shorter product compared to the homolog in
FT                   Mycobacterium tuberculosis strain H37Rv (299 aa versus 301
FT                   aa)."
FT                   /db_xref="GOA:Q7VEM2"
FT                   /db_xref="InterPro:IPR017946"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM2"
FT                   /protein_id="CAD97161.1"
FT                   /translation="MLGAVALVIALGGTCGVADALPLGQTDDPMIVAHRAGTRDFPENT
FT                   VLAITNAVAAGVDGMWLTVQVSSDGVPVLYRPSDLATLTDGAGPVNSKTVQQLQQLNAG
FT                   WNFTTPGVEGHPYRQRATPIPTLEQAIGATPPDMTLFLDPKQTPPQPLVSAVAQVLTRT
FT                   GAAGRSIVYSTNADITAAASRQEGLQVAESRDVTRQRLFNMALNHHCDPQPDPGKWAGF
FT                   ELHRDVTVTEEFTLGSGISAVNAELWDEASVDCFRSQSGMKVMGFAVKTVDDYRLAHKI
FT                   GLDAVLVDSPLAAQQWRH"
FT   CDS             18156..19535
FT                   /transl_table=11
FT                   /gene="Mb2301"
FT                   /locus_tag="Mb2301"
FT                   /product="Probable dehydrogenase"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2301, -, len: 459 aa. Equivalent to Rv2280, len:
FT                   459 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 459 aa overlap). Probable
FT                   dehydrogenase. Similar to D-lactate dehydrogenase
FT                   (cytochrome) precursor e.g. G1061264 (587 aa), FASTA
FT                   scores, opt: 645,E(): 1.3e-31, (28.0% identity in 478 aa
FT                   overlap), similar to MTCY50.25, 36.5% identity in 447 aa
FT                   overlap"
FT                   /db_xref="GOA:Q7VEM1"
FT                   /db_xref="InterPro:IPR006094"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM1"
FT                   /protein_id="CAD97162.1"
FT                   /translation="MSEMTARFSEIVGNANLLTGDAIPEDYAHDEELTGPPQKPAYAAK
FT                   PATPEEVAQLLKAASENGVPVTARGSGCGLSGAARPVEGGLLISFDRMNKVLEVDTANQ
FT                   VAVVQPGVALTDLDAATADTGLRYTVYPGELSSSVGGNVGTNAGGMRAVKYGVARHNVL
FT                   GLQAVLPTGEIIRTGGRMAKVSTGYDLTQLIIGSEGTLALVTEVIVKLHPRLDHNASVL
FT                   APFADFDQVMAAVPKILASGLAPDILEYIDNTSMAALISTQNLELGIPDQIRDSCEAYL
FT                   LVALENRIADRLFEDIQTVGEMLMELGAVDAYVLEGGSARKLIEAREKAFWAAKALGAD
FT                   DIIDTVVPRASMPKFLSTARGLAAAADGAAVGCGHAGDGNVHMAIACKDPEKKKKLMTD
FT                   IFALAMELGGAISGEHGVGRAKTGYFLELEDPVKISLMRRIKQSFDPAGILNPGVVFGD
FT                   T"
FT   CDS             19769..21427
FT                   /transl_table=11
FT                   /gene="pitB"
FT                   /locus_tag="Mb2302"
FT                   /product="Putative phosphate-transport permease PitB"
FT                   /note="Mb2302, pitB, len: 552 aa. Equivalent to Rv2281,
FT                   len: 552 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 552 aa overlap). Putative pitB,
FT                   phosphate-transport permease, integral membrane protein,
FT                   similar to YG04_HAEIN P45268 putative phosphate permease
FT                   hi1604 (420 aa). FASTA scores, opt: 484, E(): 5e-23, (33.5%
FT                   identity in 498 aa overlap) also to G399598 amphotropic
FT                   murine retrovirus receptor (656 aa) FASTA scores, opt: 453,
FT                   E(): 5.8e-21, (26.8% identity in 645 aa overlap). Also
FT                   similar to Rv0545c|pitA from M. tuberculosis. BELONGS TO
FT                   THE PIT SUBFAMILY."
FT                   /db_xref="GOA:P65713"
FT                   /db_xref="InterPro:IPR001204"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65713"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97163.1"
FT                   /translation="MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLL
FT                   LAGSFVLFSWWAFDYAGSGANKVILVLATVVGMFMAFNVGGNDVANSFGTSVGAGTLTM
FT                   KQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSGVSVDPRDFMNIMLSALSAAALWLL
FT                   FANRMGYPVSTTHSIIGGIVGAAIALGMVSGQGGAALRMVQWDQIGQIVVSWVLSPVLG
FT                   GLVSYLLYGVIKRHILLYNEQAERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGAL
FT                   ARDAVAANRKDFDPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAM
FT                   LLFKGFKHMHLGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMFSWMQVF
FT                   TASGFAFSHGSNDIANAIGPFAAILDVLRTGAIEGNAAVPAAAMVTFGVALCAGLWFIG
FT                   RRVIATVGHNLTTMHPASGFAAELSAAGVVMGATVLGLPVSSTHILIGAVLGVGIVNRS
FT                   TNWGLMKPIVLAWVITLPSAAILASVGLVALRAIF"
FT   CDS             complement(21534..22472)
FT                   /transl_table=11
FT                   /gene="Mb2303c"
FT                   /locus_tag="Mb2303c"
FT                   /product="Probable transcription regulator (lysR family)"
FT                   /note="Mb2303c, -, len: 312 aa. Equivalent to Rv2282c, len:
FT                   312 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 312 aa overlap). Probable
FT                   transcriptional regulator, lysR family, similar to others
FT                   e.g. YC30_CYAPA|P48271 hypothetical transcriptional
FT                   regulator YCF30 (324 aa), FASTA scores: opt: 292, E():
FT                   4e-12, (27.6% identity in 286 aa overlap); etc. Also
FT                   similar to Rv0377|MTCY39.34 from Mycobacterium
FT                   tuberculosis, FASTA score: (25.4% identity in 268 aa
FT                   overlap). Contains PS00044 Bacterial regulatory proteins,
FT                   lysR family signature, and contains helix-turn-helix motif
FT                   at aa 24 -45 (+4.93 SD)."
FT                   /db_xref="GOA:P67668"
FT                   /db_xref="InterPro:IPR011991"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67668"
FT                   /protein_id="CAD97164.1"
FT                   /translation="MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLAS
FT                   MEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRIRVVA
FT                   SQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIENPCP
FT                   PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALR
FT                   DTLGEDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNL
FT                   RRQLRAIWVGGRTPPAGAIRDLLSHITSRST"
FT   CDS             22537..22731
FT                   /transl_table=11
FT                   /gene="Mb2304"
FT                   /locus_tag="Mb2304"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2304, -, len: 64 aa. Equivalent to Rv2283, len: 64
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 64 aa overlap). Unknown protein; questionable
FT                   ORF"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64974"
FT                   /protein_id="CAD97165.1"
FT                   /translation="MLEKCPHASVDCGASKIGITDNDPATATNRRLASTIRKPPIEHAA
FT                   GPLGSTSRAGHRSYGGVAS"
FT   CDS             22741..24036
FT                   /transl_table=11
FT                   /gene="lipM"
FT                   /locus_tag="Mb2305"
FT                   /product="Probable esterase LipM"
FT                   /EC_number="3.1.-.-"
FT                   /note="Mb2305, lipM, len: 431 aa. Equivalent to Rv2284,
FT                   len: 431 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 431 aa overlap). Probable lipM,
FT                   esterase (EC 3.1.-.-), similar to others e.g.
FT                   gp|Z95844|MTCY493_28 from Mycobacterium tuberculosis cosmid
FT                   (420 aa), FASTA scores: opt: 1266, E(): 0, (50.1% identity
FT                   in 411 aa overlap). Some similarity to G537514
FT                   arylacetamide deacetylase (399 aa), FASTA scores: opt: 190,
FT                   E(): 5.9e-05, (30.4% identity in 138 aa overlap)."
FT                   /db_xref="GOA:Q7VEM0"
FT                   /db_xref="InterPro:IPR002018"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEM0"
FT                   /protein_id="CAD97166.1"
FT                   /translation="MGAPRLIHVIRQIGALVVAAVTAAATINAYRPLARNGFASLWSWF
FT                   IGLVVTEFPLPTLASQLGGLVLTAQRLTRPVRAVSWLVAAFSALGLLNLSRAGRQADAQ
FT                   LTAALDSGLGPDRRTASAGLWRRPAGGGTAKTPGPLRMLRIYRDYAHDGDISYGEYGRA
FT                   NHLDIWRRPDLDLTGTAPVLFQIPGGAWTTGNKRGQAHPLMSHLAELGWICVAINYRHS
FT                   PRNTWPDHIIDVKRALAWVKAHISEYGGDPDFIAITGGSAGGHLSSLAALTPNDPRFQP
FT                   GFEEADTRVQAAVPFYGVYDFTRLQDAMHPMMLPLLERMVVKQPRTANMQSYLDASPVT
FT                   HISADAPPFFVLHGRNDSLVPVQQARGFVDQLRQVSKQPVVYAELPFTQHAFDLLGSAR
FT                   AAHTAIAVEQFLAEVYATQHAGSEPGPAVAIP"
FT   CDS             24069..25406
FT                   /transl_table=11
FT                   /gene="Mb2306"
FT                   /locus_tag="Mb2306"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2306, -, len: 445 aa. Equivalent to Rv2285, len:
FT                   445 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 445 aa overlap). Conserved hypothetical
FT                   protein, member of Mycobacterium tuberculosis 15-membered
FT                   protein family including Rv3740c, Rv3734c, Rv1425, Rv1760,
FT                   Rv0895, Rv3480c. FASTA scores: gp|Z95844|MTCY493_29
FT                   Mycobacterium tuberculosis cosmid (459 aa) opt: 640, E():
FT                   0; 33.4% identity in 470 aa overlap."
FT                   /db_xref="InterPro:IPR004255"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67207"
FT                   /protein_id="CAD97167.1"
FT                   /translation="MKLLSPLDQMFARMEAPRTPMHIGAFAVFDLPKGAPRRFIRDLYE
FT                   AISQLAFLPFPFDSVIAGGASMAYWRQVQPDPSYHVRLSALPYPGTGRDLGALVERLHS
FT                   TPLDMAKPLWELHLIEGLTGRQFAMYFKAHHCAVDGLGGVNLIKSWLTTDPEAPPGSGK
FT                   PEPFGDDYDLASVLAAATTKRAVEGVSAVSELAGRLSSMVLGANSSVRAALTTPRTPFN
FT                   TRVNRHRRLAVQVLKLPRLKAVAHATDCTVNDVILASVGGACRRYLQELGDLPTNTLTA
FT                   SVPVGFERDADTVNAASGFVAPLGTSIEDPVARLTTISASTTRGKAELLAMSPNALQHY
FT                   SVFGLLPIAVGQKTGALGVIPPLFNFTVSNVVLSKDPLYLSGAKLDVIVPMSFLCDGYG
FT                   LNVTLVGYTDKVVLGFLGCRDTLPHLQRLAQYTGAAFEELETAALP"
FT   CDS             complement(25473..25736)
FT                   /transl_table=11
FT                   /gene="Mb2307c"
FT                   /locus_tag="Mb2307c"
FT                   /product="conserved hypothetical protein [SECOND PART]"
FT                   /note="Mb2307c, -, len: 87 aa. Equivalent to 3' end of
FT                   Rv2286c, len: 230 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (). Conserved hypothetical protein. Similar
FT                   to Mycobacterium tuberculosis hypothetical protein,
FT                   Rv2466c, AL021246|MTV008_22 (207 aa). FASTA score: opt:
FT                   324, E(): 8.9e-15; 30.4% identity in 194 aa overlap.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2286c exists as a single gene.
FT                   In Mycobacterium bovis, a frameshift due to a single base
FT                   transition (c-t) splits Rv2286c into 2 parts, Mb2307c and
FT                   Mb2308c."
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL9"
FT                   /protein_id="CAD97168.1"
FT                   /translation="MPTLFLDGQCLFGPVLVDPPAGPAALNLWSVVTGMAGLPHVYELQ
FT                   RPKSPADVELIAQQLRPYLDGRDWVSINRGEIVDIDRLAGRS"
FT   CDS             complement(25764..26165)
FT                   /transl_table=11
FT                   /gene="Mb2308c"
FT                   /locus_tag="Mb2308c"
FT                   /product="conserved hypothetical protein [FIRST PART]"
FT                   /note="Mb2308c, -, len: 133 aa. Equivalent to 5' end of
FT                   Rv2286c, len: 230 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (100.0% identity in 133 aa overlap).
FT                   Conserved hypothetical protein. Similar to Mycobacterium
FT                   tuberculosis hypothetical protein, Rv2466c,
FT                   AL021246|MTV008_22 (207 aa). FASTA score: opt: 324, E():
FT                   8.9e-15; 30.4% identity in 194 aa overlap.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2286c exists as a single gene.
FT                   In Mycobacterium bovis, a frameshift due to a single base
FT                   transition (c-t) splits Rv2286c into 2 parts, Mb2307c and
FT                   Mb2308c."
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL8"
FT                   /protein_id="CAD97169.1"
FT                   /translation="MTTVDFHFDPLCPFAYQTSVWIRDVRAQLGITINWRFFSLEEINL
FT                   VAGKKHPWERDWSYGWSLMRIGALLRRTNMSLLDRWYAAIGHELHTLGGKPHDPAVARR
FT                   LLCDVGVNAAILDAALDDPTTHDDVRADH"
FT   CDS             26299..27927
FT                   /transl_table=11
FT                   /gene="yjcE"
FT                   /locus_tag="Mb2309"
FT                   /product="Probable conserved integral membrane transport
FT                   protein YjcE"
FT                   /note="Mb2309, yjcE, len: 542 aa. Equivalent to Rv2287,
FT                   len: 542 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 542 aa overlap). Probable yjcE,
FT                   conserved integral membrane transport protein, similar to
FT                   eukaryote NA+/H+ exchangers e.g. YJCE_ECOLI|P32703|B4065
FT                   Putative Na(+)/H(+) exchanger from Escherichia coli (549
FT                   aa), FASTA scores: opt: 436, E(): 5.6e-21, (29.4% identity
FT                   in 555 aa overlap); etc. SEEMS TO BELONG TO CPA1 FAMILY
FT                   (NA(+)/H(+) EXCHANGER FAMILY)."
FT                   /db_xref="GOA:P65527"
FT                   /db_xref="InterPro:IPR004705"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65527"
FT                   /protein_id="CAD97170.1"
FT                   /translation="MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLI
FT                   LSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVI
FT                   ATAVAVSWTARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDG
FT                   TALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEE
FT                   GALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFL
FT                   INGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTV
FT                   DRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVV
FT                   ILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDL
FT                   VKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLID
FT                   DIVLRELQAAMDLEEVQLLDPADAE"
FT   CDS             27924..28301
FT                   /transl_table=11
FT                   /gene="Mb2310"
FT                   /locus_tag="Mb2310"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2310, -, len: 125 aa. Equivalent to Rv2288, len:
FT                   125 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 125 aa overlap). Unknown hypothetical
FT                   protein"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64976"
FT                   /protein_id="CAD97171.1"
FT                   /translation="MSRRRPLIEPATVQVLAIAFTDSFSVSLHWPQREQGCRTAILAPM
FT                   RRWCDGDVDGRKLLPPARRTGTQQRRIRPAAPRVYTTGDILRDRKGIAPWQEQREPGWA
FT                   PFGWLHEPSGARCPKADGQSV"
FT   CDS             28271..29053
FT                   /transl_table=11
FT                   /gene="cdh"
FT                   /locus_tag="Mb2311"
FT                   /product="Probable CDP-diacylglycerol pyrophosphatase Cdh
FT                   (CDP-diacylglycerol diphosphatase) (CDP-diacylglycerol
FT                   phosphatidylhydrolase)"
FT                   /EC_number="3.6.1.26"
FT                   /note="Mb2311, cdh, len: 260 aa. Equivalent to Rv2289, len:
FT                   260 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 260 aa overlap). Probable cdh,
FT                   CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26), similar
FT                   to CDH_SALTY|P26219 cdp-diacylglycerol pyrophosphatase (251
FT                   aa), FASTA scores: opt: 395, E(): 5.9e-20, (33.5% identity
FT                   in 221 aa overlap)."
FT                   /db_xref="GOA:P63752"
FT                   /db_xref="InterPro:IPR003763"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63752"
FT                   /protein_id="CAD97172.1"
FT                   /translation="MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALW
FT                   KIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRE
FT                   SAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAA
FT                   LRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASI
FT                   AVANVAQDQFLLLLAEGTEDQPVAAETLQDHDCSITKS"
FT   CDS             29195..29350
FT                   /transl_table=11
FT                   /gene="lppOa"
FT                   /locus_tag="Mb2312"
FT                   /product="Probable conserved lipoprotein lppOa"
FT                   /note="Mb2312, lppOa, len: 51 aa. Equivalent to 5' end of
FT                   Rv2290, len: 171 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (100.0% identity in 39 aa overlap). Probable lppO,
FT                   conserved lipoprotein, similar to Rv3763, 19KD_MYCTU P11572
FT                   19 kd lipoprotein antigen precursor (159 aa) FASTA scores,
FT                   opt: 119, E (): 1.3, (25.6% identity in 164 aa overlap).
FT                   ???Contains appropriately positioned PS00013 lipoprotein
FT                   motif (with one mismatch). REMARK-M.bovis-M.tuberculosis:
FT                   In Mycobacterium tuberculosis strain H37Rv, lppO exists as
FT                   a single gene. In Mycobacterium bovis, a frameshift due to
FT                   a single base deletion (c-*), splits lppO into 2 parts,
FT                   lppOa and lppOb."
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL7"
FT                   /protein_id="CAD97173.1"
FT                   /translation="MTDPRHTVRIAVGATALGVSALGATLPACSAHSGPGSPPVRRQLP
FT                   RPRPSW"
FT   CDS             29344..29709
FT                   /transl_table=11
FT                   /gene="lppOb"
FT                   /locus_tag="Mb2313"
FT                   /product="Probable conserved lipoprotein lppOb"
FT                   /note="Mb2313, lppOb, len: 121 aa. Equivalent to 3' end of
FT                   Rv2290, len: 171 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (99.2% identity in 121 aa overlap). Probable lppO,
FT                   conserved lipoprotein, similar to Rv3763, 19KD_MYCTU P11572
FT                   19 kd lipoprotein antigen precursor (159 aa) FASTA scores,
FT                   opt: 119, E (): 1.3, (25.6% identity in 164 aa overlap).
FT                   Contains appropriately positioned PS00013 lipoprotein motif
FT                   (with one mismatch). REMARK-M.bovis-M.tuberculosis: In
FT                   Mycobacterium tuberculosis strain H37Rv, lppO exists as a
FT                   single gene. In Mycobacterium bovis, a frameshift due to a
FT                   single base deletion (c-*), splits lppO into 2 parts, lppOa
FT                   and lppOb."
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL6"
FT                   /protein_id="CAD97174.1"
FT                   /translation="MVEGHTHTISGAVECRTSPAVRTATPSESGTQTTRVNAHDDSASV
FT                   TLSLSDSTPPDVNGFGISLKIGSVDYQMPYQPVQSPTQVEATRQGKSYTLTGTGHAVIP
FT                   GQTGMRELPFGVHVTCP"
FT   CDS             29851..30621
FT                   /transl_table=11
FT                   /gene="sseB"
FT                   /locus_tag="Mb2314"
FT                   /product="Probable thiosulfate sulfurtransferase SseB"
FT                   /EC_number="2.-.-.-"
FT                   /note="Mb2314, sseB, len: 256 aa. Equivalent to 3' end of
FT                   Rv2291, len: 284 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (99.2% identity in 256 aa overlap). Probable sseB,
FT                   thiosulfate sulfurtransferase. Very similar to thiosulfate
FT                   sulfurtransferas/rhodanese from Streptomyces coelicolor
FT                   AL00920 4|SC9B10_21 (283 aa) opt: 765, E(): 0;
FT                   Smith-Waterman score: 765; 46.9% identity in 286 aa
FT                   overlap, similar to THTR_ECOLI P31142 putative thiosulfate
FT                   sulfurtransferase (280 aa), FASTA scores, opt: 478, E():
FT                   1e-23, (35.1% identity in 265 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,
FT                   truncation at the 5' start due to a 2 bp deletion (tg-*),
FT                   leads to a shorter product compared to its homolog in
FT                   Mycobacterium tuberculosis strain H37Rv (256 aa versus 284
FT                   aa)."
FT                   /db_xref="GOA:Q7VEL5"
FT                   /db_xref="HSSP:1URH"
FT                   /db_xref="InterPro:IPR001763"
FT                   /db_xref="UniProtKB/TrEMBL:Q7VEL5"
FT                   /protein_id="CAD97175.1"
FT                   /translation="MRWRLDEPDGHAAYLQGHLPGAVFVSLEDELSDHTIAGRGRHPLP
FT                   SGASLQATVRRCGIRHDVPVVVYDDWNRAGSARAWWVLTAAGIANVRILDGGLPAWRSA
FT                   GGSIETGQVSPQLGNVTVLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDVEPV
FT                   DAVAGHIPGAINVPSGSVLADDGTFLGNGALNALLSDHGIDHGGRVGVYCGSGVSAAVI
FT                   VAALAVIGQDAALFPGSWSEWSSDPTRPVGRGTA"
FT   CDS             complement(30622..31626)
FT                   /transl_table=11
FT                   /gene="Mb2315c"
FT                   /locus_tag="Mb2315c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2315c, -, len: 334 aa. Similar to Rv2293c and
FT                   Rv2292c, len: 246 aa and 74 aa, from Mycobacterium
FT                   tuberculosis strain H37Rv, (92.2% identity in 245 aa
FT                   overlap and 100.0% identity in 74 aa overlap). Conserved
FT                   hypothetical protein; some similarity to hypothetical
FT                   protein (299 aa) AAK24237.1| (AE005897) belonging to
FT                   phosphorylase family [Caulobacter crescentus] (33% identity
FT                   in 131 aa overlap). Possible lipoprotein: signal peptide at
FT                   N-terminus. REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2293c and Rv2292c exist as 2
FT                   genes. In Mycobacterium bovis, a single base insertion
FT                   (*-g) results in a single product which is more similar to
FT                   Rv2293c."
FT                   /db_xref="GOA:P64978"
FT                   /db_xref="InterPro:IPR000845"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64978"
FT                   /protein_id="CAD97176.1"
FT                   /translation="MGAPLRHCLLVAAALSLGCGVAAADPGYVANVIPCEQRTLVLSAF
FT                   PAEADAVLAHTALDANPVVVADRRRYYLGSISGKKVIVAMTGIGLVNATNTTETAFARF
FT                   TCASSIAIAAVMFSGVAGGAGRTSIGDVAIPARWTLDNGATFRGVDPGMLATAQTLSVV
FT                   LDNINTLGNPVCLCRNVPVVRLNHLGRQPQLFVGGDGSSSDKNNGQAFPCIPNGGSVFG
FT                   CQPCSAPDRSLGYTGNFFQAAGPWLKNALISNLNIVSTVNPGFDAVDQETAAAQAVADA
FT                   HGVPFLGIRGMSDGPGDPLHLPGFPVQFFVYKQIAANNAARVTEAFLQNWAGV"
FT   CDS             31921..33144
FT                   /transl_table=11
FT                   /gene="Mb2316"
FT                   /locus_tag="Mb2316"
FT                   /product="Probable aminotransferase"
FT                   /EC_number="2.6.1.-"
FT                   /note="Mb2316, -, len: 407 aa. Equivalent to Rv2294, len:
FT                   407 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 407 aa overlap). Probable
FT                   aminotransferase (EC 2.6.1.-), similar to others in M.
FT                   tuberculosis e.g. MTV030_19, also similar to
FT                   PATB_BACSU|Q08432 putative aminotransferase b from Bacillus
FT                   subtilis (387 aa), FASTA scores: opt: 563, E(): 2 .8e-29,
FT                   (31.4% identity in 408 aa overlap); and to
FT                   MALY_ECOLI|P23256 maly protein from Escherichia coli (390
FT                   aa), FASTA scores: opt: 530, E(): 3.6e-27, (31.3% identity
FT                   in 384 aa overlap). BELONGS TO CLASS-II OF
FT                   PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES."
FT                   /db_xref="GOA:P63503"
FT                   /db_xref="HSSP:1D2F"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63503"
FT                   /protein_id="CAD97177.1"
FT                   /translation="MIPNPLEELTLEQLRSQRTSMKWRAHPADVLPLWVAEMDVKLPPT
FT                   VADALRRAIDDGDTGYPYGTEYAEAVREFACQRWQWHDLEVSRTAIVPDVMLGIVEVLR
FT                   LITDRGDPVIVNSPVYAPFYAFVSHDGRRVIPAPLRGDGRIDLDALQEAFSSARASSGS
FT                   SGNVAYLLCNPHNPTGSVHTADELRGIAERAQRFGVRVVSDEIHAPLIPSGARFTPYLS
FT                   VPGAENAFALMSASKAWNLGGLKAALAIAGREAAADLARMPEEVGHGPSHLGVIAHTAA
FT                   FRTGGNWLDALLRGLDHNRTLLGALVDEHLPGVQYRWPQGTYLAWLDCRELGFDDAASD
FT                   EMTEGLAVVSDLSGPARWFLDHARVALSSGHVFGIGGAGHVRINFATSRAILIEAVSRM
FT                   SRSLLERR"
FT   CDS             33367..34005
FT                   /transl_table=11
FT                   /gene="Mb2317"
FT                   /locus_tag="Mb2317"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2317, -, len: 212 aa. Equivalent to Rv2295, len:
FT                   212 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 212 aa overlap). Conserved hypothetical
FT                   protein, cysteine-rich protein, similar to YIEJ_ECOLI
FT                   P31469 hypothetical 22.5 kd protein in tnab-bglb intergenic
FT                   region (195 aa), opt: 270, E(): 3.4e-11, (36.4% identity in
FT                   198 aa overlap). Alternative start suggested by similarity
FT                   26 codons further downstream"
FT                   /db_xref="InterPro:IPR005363"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67310"
FT                   /protein_id="CAD97178.1"
FT                   /translation="MDQSANHACLPTPLASTTGRGQDHEMPVEETSTPQKLPQFRYHPD
FT                   PVGTGSIVADEVSCVSCEQRRPYTYTGPVYAEEELNEAICPWCIADGSAASRFDATFTD
FT                   AMWAVPDDVPEDVTEEVLCRTPGFTGWLQEEWLHHCGDAAAFLGPVGASEVADLPDALD
FT                   ALRNEYRGYDWPADKIEEFILTLDRNGLATAYLFRCLSCGVHLAYADFA"
FT   CDS             34099..35001
FT                   /transl_table=11
FT                   /gene="Mb2318"
FT                   /locus_tag="Mb2318"
FT                   /product="Probable haloalkane dehalogenase"
FT                   /EC_number="3.8.1.5"
FT                   /note="Mb2318, -, len: 300 aa. Equivalent to Rv2296, len:
FT                   300 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 300 aa overlap). Probable haloalkane
FT                   dehalogenase (EC 3.8.1.5), similar to e.g. HALO_XANAU
FT                   P22643, haloalkane dehalogenase, (310 aa), opt: 510
FT                   z-score: 577.7 E(): 3.1e-25 (39.0% identity in 315 aa
FT                   overlap)."
FT                   /db_xref="GOA:P64302"
FT                   /db_xref="HSSP:1HDE"
FT                   /db_xref="InterPro:IPR000639"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64302"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97179.1"
FT                   /translation="MDVLRTPDSRFEHLVGYPFAPHYVDVTAGDTQPLRMHYVDEGPGD
FT                   GPPIVLLHGEPTWSYLYRTMIPPLSAAGHRVLAPDLIGFGRSDKPTRIEDYTYLRHVEW
FT                   VTSWFENLDLHDVTLFVQDWGSLIGLRIAAEHGDRIARLVVANGFLPAAQGRTPLPFYV
FT                   WRAFARYSPVLPAGRLVNFGTVHRVPAGVRAGYDAPFPDKTYQAGARAFPRLVPTSPDD
FT                   PAVPANRAAWEALGRWDKPFLAIFGYRDPILGQADGPLIKHIPGAAGQPHARIKASHFI
FT                   QEDSGTELAERMLSWQQAT"
FT   CDS             35033..35485
FT                   /transl_table=11
FT                   /gene="Mb2319"
FT                   /locus_tag="Mb2319"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2319, -, len: 150 aa. Equivalent to Rv2297, len:
FT                   150 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 150 aa overlap). Unknown protein;
FT                   contains PS00343 Gram-positive cocci surface proteins
FT                   'anchoring' hexapeptide"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64980"
FT                   /protein_id="CAD97180.1"
FT                   /translation="MAMEMAMMGLLGTVVGASAMGIGGIAKSIAEAYVPGVAAAKDRRQ
FT                   QMNVDLQARRYEAVRVWRSGLCSASNAYRQWEAGSRDTHAPNVVGDEWFEGLRPHLPTT
FT                   GEAAKFRTAYEVRCDNPTLMVLSLEIGRIEKEWMVEASGRTPKHRG"
FT   CDS             35677..36648
FT                   /transl_table=11
FT                   /gene="Mb2320"
FT                   /locus_tag="Mb2320"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2320, -, len: 323 aa. Equivalent to Rv2298, len:
FT                   323 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 323 aa overlap). Conserved hypothetical
FT                   protein. Similar to SLR0545 Synechocystis sp, Q55493
FT                   hypothetical 34.6 kDa protein (314 aa), FASTA scores, opt:
FT                   427, E(): 1.7e-20, (39.3% identity in 303 aa overlap) and
FT                   to YZAE_BACSU P46905 hypothetical protein in natb 3'region
FT                   (268 aa) FASTA scores, opt: 370, E(): 6.1e-17, (31.4%
FT                   identity in 264 aa overlap)"
FT                   /db_xref="GOA:P63485"
FT                   /db_xref="HSSP:2ALR"
FT                   /db_xref="InterPro:IPR001395"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63485"
FT                   /protein_id="CAD97181.1"
FT                   /translation="MKYLDVDGIGQVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRA
FT                   RALGVTLFDTAEIYGLGKSERILGEALGDDRTEVVVASKVFPVAPFPAVIKNRERASAR
FT                   RLQLNRIPLYQIHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGR
FT                   PVVSNQVHFSLAHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALN
FT                   PLFGTENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNV
FT                   AAADIELSAQSRDALTDAARAFRPVSTGRFLTDMVREKVSRR"
FT   CDS             complement(36654..38597)
FT                   /transl_table=11
FT                   /gene="htpG"
FT                   /locus_tag="Mb2321c"
FT                   /product="PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK
FT                   PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN
FT                   G)"
FT                   /note="Mb2321c, htpG, len: 647 aa. Equivalent to Rv2299c,
FT                   len: 647 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 647 aa overlap). htpG, probable
FT                   chaperone, HSP90 familyHEAT SHOCK PROTEIN HSP90 FAMILY.
FT                   Similar to HTPG_BACSU|P46208 heat shock protein htpG
FT                   homologue from Bacillus subtilis (626 aa), FASTA scores:
FT                   opt: 1551, E(): 0, (39.6% identity in 631 aa overlap).
FT                   Contains possible helix-turn-helix motif at aa 519-540
FT                   (+3.77 SD). BELONGS TO THE HEAT SHOCK PROTEIN 90 FAMILY."
FT                   /db_xref="GOA:P64412"
FT                   /db_xref="HSSP:1YER"
FT                   /db_xref="InterPro:IPR001404"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64412"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97182.1"
FT                   /translation="MNAHVEQLEFQAEARQLLDLMVHSVYSNKDAFLRELISNASDALD
FT                   KLRIEALRNKDLEVDTSDLHIEIDADKAARTLTVRDNGIGMAREEVVDLIGTLAKSGTA
FT                   ELRAQLREAKNAAASEELIGQFGIGFYSSFMVADKVQLLTRKAGESAATRWESSGEGTY
FT                   TIESVEDAPQGTSVTLHLKPEDAEDDLHDYTSEWKIRNLVKKYSDFIAWPIRMDVERRT
FT                   PASQEEGGEGGEETVTIETETLNSMKALWARPKEEVSEQEYKEFYKHVAHAWDDPLEII
FT                   AMKAEGTFEYQALLFIPSHAPFDLFDRDAHVGIQLYVKRVFIMGDCDQLMPEYLRFVKG
FT                   VVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKDVQSSRPEDYRTFWTQFGRVL
FT                   KEGLLSDIDNRETLLGISSFVSTYSEEEPTTLAEYVERMKDGQQQIFYATGETRQQLLK
FT                   SPHLEAFKAKGYEVLLLTDPVDEVWVGMVPEFDGKPLQSVAKGEVDLSSEEDTSEAERE
FT                   ERQKEFADLLTWLQETLSDHVKEVRLSTRLTESPACLITDAFGMTPALARIYRASGQEV
FT                   PVGKRILELNPSHPLVTGLRQAHQDRADDAEKSLAETAELLYGTALLAEGGALEDPARF
FT                   AELLAERLARTL"
FT   CDS             complement(38671..39603)
FT                   /transl_table=11
FT                   /gene="Mb2322c"
FT                   /locus_tag="Mb2322c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2322c, -, len: 310 aa. Equivalent to Rv2300c, len:
FT                   310 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 310 aa overlap). Conserved hypothetical
FT                   protein, similar to others e.g. Q9RXY2|DR0172 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Deinococcus radiodurans (271 aa),
FT                   FASTA scores: opt: 306, E(): 1.3e-12, (34.6% identity in
FT                   229 aa overlap); Q9HZH1|PA3037 HYPOTHETICAL PROTEIN from
FT                   Pseudomonas aeruginosa (288 aa), FASTA scores: opt: 248,
FT                   E(): 7.9e-09, (31.5% identity in 238 aa overlap);
FT                   Q9PDL8|XF1361 HYPOTHETICAL PROTEIN from Xylella fastidiosa
FT                   (279 aa), FASTA scores: opt: 236, E(): 4.6e-08, (29.7%
FT                   identity in 249 aa overlap); U70053|XCU70053_3 GumP PROTEIN
FT                   from Xanthomonas campestris (282 aa), FASTA scores: opt:
FT                   222, E(): 3.7e-07, (30.1% identity in 248 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:P64982"
FT                   /db_xref="InterPro:IPR001279"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64982"
FT                   /protein_id="CAD97183.1"
FT                   /translation="MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPE
FT                   AKGPPVKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRH
FT                   VLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARG
FT                   AIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHT
FT                   RGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARI
FT                   VELHRRHDPDLLIVCAHDPDLYQLARDTA"
FT   CDS             39610..40302
FT                   /transl_table=11
FT                   /gene="cut2"
FT                   /locus_tag="Mb2323"
FT                   /standard_name="cfp25"
FT                   /product="PROBABLE CUTINASE CUT2"
FT                   /EC_number="3.1.1.-"
FT                   /note="Mb2323, cut2, len: 230 aa. Equivalent to Rv2301,
FT                   len: 230 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 230 aa overlap). Probable cut2
FT                   (alternate gene name: cfp25), cutinase (EC 3.1.1.-), highly
FT                   similar to others from Mycobacteria tuberculosis e.g.
FT                   MTCY13E12.04|Rv3451|O06318|CUT3_MYCTU (247 aa), FASTA
FT                   scores: opt: 569, E(): 2.3e-27, (45.3% identity in 223 aa
FT                   overlap); MT2037|MTCY39.35|RV1984C|Q10837|CUT1_MYCTU (217
FT                   aa), FASTA scores: opt: 383, E(): 3.4e-16 (42.9% identity
FT                   in 217 aa overlap); O69691|Rv3724|MTV025.072 PUTATIVE
FT                   CUTINASE PRECURSOR (187 aa), FASTA scores: opt: 248, E():
FT                   4.3e-08, (41.85% identity in 172 aa overlap); etc. Also
FT                   similar to few others from other organisms e.g. Q9KK87
FT                   SERINE ESTERASE CUTINASE from Mycobacterium avium (220 aa),
FT                   FASTA scores: opt: 391, E(): 1.1e-16, (39.15% identity in
FT                   235 aa overlap); etc. Contains PS00095 C-5
FT                   cytosine-specific DNA methylases C-terminal signature.
FT                   BELONGS TO THE CUTINASE FAMILY. Start changed since first
FT                   submission (+11 aa)."
FT                   /db_xref="GOA:P63882"
FT                   /db_xref="HSSP:1CUW"
FT                   /db_xref="InterPro:IPR017909"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63882"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97184.1"
FT                   /translation="MNDLLTRRLLTMGAAAAMLAAVLLLTPITVPAGYPGAVAPATAAC
FT                   PDAEVVFARGRFEPPGIGTVGNAFVSALRSKVNKNVGVYAVKYPADNQIDVGANDMSAH
FT                   IQSMANSCPNTRLVPGGYSLGAAVTDVVLAVPTQMWGFTNPLPPGSDEHIAAVALFGNG
FT                   SQWVGPITNFSPAYNDRTIELCHGDDPVCHPADPNTWEANWPQHLAGAYVSSGMVNQAA
FT                   DFVAGKLQ"
FT   CDS             40408..40650
FT                   /transl_table=11
FT                   /gene="Mb2324"
FT                   /locus_tag="Mb2324"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2324, -, len: 80 aa. Equivalent to Rv2302, len: 80
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 80 aa overlap). Conserved hypothetical protein,
FT                   highly similar to others: O53766|AL021942|Rv0569|MTV039.07
FT                   HYPOTHETICAL 9.5 KDA PROTEIN from Mycobacterium
FT                   tuberculosis (88 aa), FASTA scores: opt: 300, E(): 1.4e-14,
FT                   (61.85% identity in 76 aa overlap); O88049|SCI35.11
FT                   HYPOTHETICAL 7.1 KDA PROTEIN from Streptomyces coelicolor
FT                   (64 aa), FASTA scores: opt: 169, E(): 1.5e-05, (46.55%
FT                   identity in 58 aa overlap) (has its C-terminus shorter);
FT                   Q9XCD1 HYPOTHETICAL 12.0 KDA PROTEIN (FRAGMENT) from
FT                   Thermomonospora fusca (106 aa), FASTA scores: opt: 126,
FT                   E(): 0.023, (50.0% identity in 34 aa overlap) (similarity
FT                   in part for this one). Also weakly similar to
FT                   U650M|G699303|Q50105 HYPOTHETICAL 5.7 KDA PROTEIN from
FT                   Mycobacterium leprae (53 aa), FASTA scores: opt: 89, E():
FT                   0.66, (45.5% identity in 33 aa overlap); and weakly similar
FT                   to N-terminus of Q9RIZ1|SCJ1.23c putative DNA-binding
FT                   protein from Streptomyces coelicolor (323 aa), FASTA
FT                   scores: opt: 182, E(): 7.3e-06, (42.25% identity in 71 aa
FT                   overlap)."
FT                   /db_xref="InterPro:IPR015035"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64984"
FT                   /protein_id="CAD97185.1"
FT                   /translation="MHAKVGDYLVVKGTTTERHDQHAEIIEVRSADGSPPYVVRWLVNG
FT                   HETTVYPGSDAVVVTATEHAEAEKRAAARAGHAAT"
FT   CDS             complement(40691..41614)
FT                   /transl_table=11
FT                   /gene="Mb2325c"
FT                   /locus_tag="Mb2325c"
FT                   /product="PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN"
FT                   /note="Mb2325c, -, len: 307 aa. Equivalent to Rv2303c, len:
FT                   307 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 307 aa overlap). Probable
FT                   antibiotic-resistance protein, with some similarity to
FT                   Q54229|G153373 macrotetrolide antibiotic-resistance protein
FT                   (NONR) from Streptomyces griseus (347 aa) (see the first
FT                   citation below), FASTA scores: opt: 438, E(): 3.1e-21,
FT                   (33.2% identity in 226 aa overlap); and other hypothetical
FT                   proteins e.g. P95886 ORF C02006 from Sulfolobus
FT                   solfataricus (269 aa), FASTA scores: opt: 252, E():
FT                   3.5e-09, (25.5% identity in 286 aa overlap). Also similar
FT                   to Mycobacterium tuberculosis Rv3510c|O53555|MTV023.17.
FT                   Note that the protein Q9XDF3|NONC from Streptomyces griseus
FT                   subsp. griseus (317 aa) is equivalent to
FT                   Q54229|G153373|NONR however the N-terminal end is shorter
FT                   (30 aa) owing to a changed start codon (see the second
FT                   citation below)."
FT                   /db_xref="GOA:Q7TYV6"
FT                   /db_xref="InterPro:IPR006992"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV6"
FT                   /protein_id="CAD97186.1"
FT                   /translation="MTAPEPRVPVIDMWAPFVPSAEVIDDLREGFPVELLSYFEVFTKT
FT                   TISAEQFGAYAESLRRTDDQILDSLDDAGITRSLITGFDERSTCGVTFVHNASVAAVAA
FT                   RYPDRFLPFAGADILAGDSAVDEFERWVVEHGFRGLSLRPFMIGRPASDPAYFPCYAKC
FT                   VELGVPVSIHTSADWTRTRLSDLGHPRHIDDVACRFPELTILMSHGGYPWVLQACLIAW
FT                   KHPNVYLELAAHRPKYFASPGAGWEPLMRFGQTTIRNKIVYGTGGFLINRPYLQLCDEM
FT                   RALPVPREVLEDWLWRNATRVLRLDT"
FT   CDS             complement(41611..41820)
FT                   /transl_table=11
FT                   /gene="Mb2326c"
FT                   /locus_tag="Mb2326c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2326c, -, len: 69 aa. Equivalent to Rv2304c, len:
FT                   69 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 69 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64986"
FT                   /protein_id="CAD97187.1"
FT                   /translation="MSHDIATEEADDGALDRCVLCDLTGKRVDVKEATCTGRPATTFEQ
FT                   AFAVERDAGFDDFLHGPVGPRSTP"
FT   CDS             42404..43693
FT                   /transl_table=11
FT                   /gene="Mb2327"
FT                   /locus_tag="Mb2327"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2327, -, len: 429 aa. Equivalent to Rv2305, len:
FT                   429 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 429 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="InterPro:IPR001242"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV5"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97188.1"
FT                   /translation="MTQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALR
FT                   AAVAKHALARARLGRASLTARTLYWEVPDRADHLAVEITDEPVGEVRSRFYARAPELHR
FT                   SPVFAVAVVRETVGDRLLLNFHHAAFDGMGGLRLLLSLARAYADEPDEVGGPPIEEARN
FT                   LKGVAGSRDLFDVLIRARGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMAT
FT                   AVARRPEGATVNDLAMAALALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNF
FT                   ASYLAIVLRVDEVTDLEKATAIVAGITGPLKQSGAAGWVVDLLEGGKVLPAMLKRQLQL
FT                   LLPLVEDRFVESVCLSNLGRVDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGT
FT                   LRAMFRGDGRTIGGEALGRFAALYRDTLLT"
FT   CDS             43703..44296
FT                   /transl_table=11
FT                   /gene="Mb2328"
FT                   /locus_tag="Mb2328"
FT                   /product="POSSIBLE CONSERVED MEMBRANE PROTEIN"
FT                   /note="Mb2328, -, len: 197 aa. Equivalent to Rv2306A, len:
FT                   197 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.5% identity in 197 aa overlap). Possible conserved
FT                   membrane protein, similar to several hypothetical membrane
FT                   proteins from Mycobacterium tuberculosis and Streptomyces
FT                   coelicolor, e.g. Rv0625c|P96915|Y625_MYCTU HYPOTHETICAL
FT                   25.2 KDA PROTEIN from Mycobacterium tuberculosis (246 aa),
FT                   FASTA scores: opt: 410, E(): 2.7e-17, (53.25% identity in
FT                   139 aa overlap). First 140 aa show high similarity, this
FT                   then decreases but continues in next ORF Rv2306B,
FT                   suggesting a frameshift near nt 2577473. However the
FT                   sequence has been checked and no error found. The sequence
FT                   is identical in CDC1551 and Mycobacterium bovis. Replaces
FT                   original Rv2306c on other strand."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV4"
FT                   /protein_id="CAD97189.1"
FT                   /translation="MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRS
FT                   AVVVATGPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAG
FT                   MTPRRCWVSIAPIASMHRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGR
FT                   SSGRRHGCSSTPRWARRSPTCRRRWFTRRSRCGA"
FT   CDS             44083..44517
FT                   /transl_table=11
FT                   /gene="Mb2329"
FT                   /locus_tag="Mb2329"
FT                   /product="POSSIBLE CONSERVED MEMBRANE PROTEIN"
FT                   /note="Mb2329, -, len: 144 aa. Equivalent to Rv2306B, len:
FT                   144 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 144 aa overlap). Possible conserved
FT                   membrane protein, similar to C-terminal part of several
FT                   hypothetical membrane proteins from Mycobacterium
FT                   tuberculosis and Streptomyces coelicolor e.g.
FT                   P96915|Y625_MYCTU|RV0625c HYPOTHETICAL 25.2 KDA PROTEIN
FT                   from Mycobacterium tuberculosis (246 aa), FASTA scores:
FT                   opt: 480, E(): 5e-24, (77.15% identity in 92 aa overlap).
FT                   Could be a continuation of Rv2306A suggesting there may be
FT                   a frameshift near nt 2577473. The C-terminal part is longer
FT                   than Rv0625c and the 3'-end of gene overlaps Rv2307c, so
FT                   maybe a further framehift. However, sequence has been
FT                   checked and no error found. Also same sequence as strain
FT                   CDC1551 and Mycobacterium bovis. Replaces original Rv2306c
FT                   on other strand."
FT                   /db_xref="InterPro:IPR015414"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV3"
FT                   /protein_id="CAD97190.1"
FT                   /translation="MWAVVGQRFVPGISDALASYTFGAFGVPLWQMVVGSFIGSAPRVF
FT                   VYTALGASITNLSSPLVYSAIAVWCVTAIIGAFAARRWYRKWRARPRRRCGLAQLTTGS
FT                   QQRHTSHRTPAGVVMPGSLSEHRRLRQEAPDRIEHHPPIE"
FT   CDS             complement(44446..45291)
FT                   /transl_table=11
FT                   /gene="Mb2330c"
FT                   /locus_tag="Mb2330c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2330c, -, len: 281 aa. Equivalent to Rv2307c, len:
FT                   281 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.3% identity in 281 aa overlap). Conserved hypothetical
FT                   protein, similar to many other hypothetical proteins and
FT                   BEM1/BUD5 suppressors e.g. P77538 HYPOTHETICAL PROTEIN from
FT                   Escherichia coli (293 aa), FASTA scores: opt: 421, E():
FT                   2.4e-18, (32.1% identity in 268 aa overlap) (alias
FT                   AAG57647|Z3802|BAB36823|ECS3400 Putative enzyme (3.4.-)
FT                   from Escherichia coli (293 aa), FASTA scores: opt: 425,
FT                   E(): 1.7e-18, (32.1% identity in 268 aa
FT                   overlap));P54069|BE46_SCHPO|BEM46|SPBC32H8.03|PI020 BEM46
FT                   PROTEIN from Schizosaccharomyces pombe (Fission yeast) (352
FT                   aa), FASTA scores: opt: 355, E(): 3.3e-14, (30.45% identity
FT                   in 279 aa overlap); O76462|BEM46 BEM46 PROTEIN from
FT                   Drosophila melanogaster (338 aa), FASTA scores: opt: 404,
FT                   E(): 2.8e-17, (32.75% identity in 281 aa overlap); etc.
FT                   Equivalent (but with few differences) to AAK46650|MT2364
FT                   protein from Mycobacterium tuberculosis strain CDC1551 (281
FT                   aa)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV2"
FT                   /protein_id="CAD97191.1"
FT                   /translation="MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSA
FT                   SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAELAVALHGL
FT                   GLSVLLFDYRGYGGNPGRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAAVAV
FT                   GLAVQRPPAALVLRSPFTSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAG
FT                   GSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ
FT                   "
FT   CDS             complement(45823..46014)
FT                   /transl_table=11
FT                   /gene="Mb2331c"
FT                   /locus_tag="Mb2331c"
FT                   /product="HYPOTHETICAL GLYCINE RICH PROTEIN"
FT                   /note="Mb2331c, -, len: 63 aa. Equivalent to Rv2307A, len:
FT                   63 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 63 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV1"
FT                   /protein_id="CAD97192.1"
FT                   /translation="MAFVDLRYPWCRGDGWISPPVVAVALGWAMRRKPFSRFNEYVGSA
FT                   SNTCWFARALELRTLLIR"
FT   CDS             complement(46099..46530)
FT                   /transl_table=11
FT                   /gene="Mb2332c"
FT                   /locus_tag="Mb2332c"
FT                   /product="HYPOTHETICAL GLYCINE RICH PROTEIN"
FT                   /note="Mb2332c, -, len: 143 aa. Equivalent to Rv2307B, len:
FT                   143 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 143 aa overlap). Hypothetical unknown
FT                   Gly- rich protein. Equivalent to AAK46653 from
FT                   Mycobacterium tuberculosis strain CDC1551 (133 aa) but
FT                   longer 10 aa."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYV0"
FT                   /protein_id="CAD97193.1"
FT                   /translation="MEEVPTGPPAMGHRACGGQKAAFPTRMNSGVEKMYKNSIAIAIGT
FT                   LTMAVEFSMVSANAEPAPPPGQDPHMPNSAMGYCPGGGFGGITGWGYCDGIRYPDGSYW
FT                   HQVRVPAPFVGTTLTLSCVIDDGSPVPPLAAPGSCGGGA"
FT   CDS             complement(46623..46805)
FT                   /transl_table=11
FT                   /gene="Mb2333c"
FT                   /locus_tag="Mb2333c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2333c, -, len: 60 aa. Equivalent to Rv2307D, len:
FT                   60 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 60 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU9"
FT                   /protein_id="CAD97194.1"
FT                   /translation="MWRHLWLMQPQRRYPRGSGTTRTARRDAGVAPLYGVSRVTVLAST
FT                   TATTAPPVKSFPDLL"
FT   CDS             47014..47730
FT                   /transl_table=11
FT                   /gene="Mb2334"
FT                   /locus_tag="Mb2334"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2334, -, len: 238 aa. Equivalent to Rv2308, len:
FT                   238 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 238 aa overlap). Conserved hypothetical
FT                   protein, sharing similarity with O53464|Rv2018|MTV018.05
FT                   from Mycobacterium tuberculosis (239 aa), FASTA scores:
FT                   opt: 142, E(): 0.034, (24.8% identity in 250 aa overlap).
FT                   As contains possible helix-turn-helix motif at aa 16-37
FT                   (Sequence: YVYAEVDKLIGLPAGTAKRWIN) (Score 1169, +3.17 SD),
FT                   may be a transcriptional regulator."
FT                   /db_xref="InterPro:IPR007367"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU8"
FT                   /protein_id="CAD97195.1"
FT                   /translation="MRADMSVTSMLDREVYVYAEVDKLIGLPAGTAKRWINGYERGVKD
FT                   HPPILRVTPGATPWVTWGEFVETRMLAEYRDRRKVPIVRQRAAIEELRARFNLRYPLAH
FT                   LRPFLSTHERDLTMGGEEIGLPDAEVTIRTGQALLGDARWLASIATPGRDEVGEAVIVE
FT                   LPVDKAFPEIVINPSRYSGQPTFVGRRVSPVTIAQMVDGGEEREDLAADYGLSLKQIQD
FT                   AIDYTKKYRLARLVAA"
FT   tRNA            complement(48359..48432)
FT                   /gene="metV"
FT                   /locus_tag="metV"
FT                   /note="metV, len: 74 nt. Equivalent to metV, len: 74 nt,
FT                   from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 74 nt overlap). tRNA-Met, anticodon cat."
FT   CDS             complement(48438..48893)
FT                   /transl_table=11
FT                   /gene="Mb2335c"
FT                   /locus_tag="Mb2335c"
FT                   /product="POSSIBLE INTEGRASE (FRAGMENT)"
FT                   /note="Mb2335c, -, len: 151 aa. Equivalent to Rv2309c, len:
FT                   151 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 151 aa overlap). Possible integrase
FT                   (fragment), similar to others e.g. Q48908 INTEGRASE
FT                   (FRAGMENT) from Mycobacterium paratuberculos (191 aa),
FT                   FASTA scores: opt: 279, E(): 3.2e-11, (40.4% identity in
FT                   136 aa overlap); etc. Also similar to others from
FT                   Mycobacterium tuberculosis e.g. Rv1055|MTV017.08 INTEGRASE
FT                   (FRAGMENT) (78 aa) (72.85% identity in 70 aa overlap); and
FT                   Rv1054|MTV017.07 INTEGRASE (FRAGMENT). COULD BELONG TO THE
FT                   'PHAGE' INTEGRASE FAMILY."
FT                   /db_xref="GOA:Q7TYU7"
FT                   /db_xref="HSSP:1AIH"
FT                   /db_xref="InterPro:IPR014417"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU7"
FT                   /protein_id="CAD97196.1"
FT                   /translation="MTGAGIVETTTNRVRHVPVPEPVSERLRDELPTEPNALVFPSYRG
FT                   GHLPIEEYRRAFDKGCKAVGIADLVPHGLRHTTASLAISAGANVKVVQRLLGHATAAMT
FT                   LDRHGHLLSDDLAGVAGLLVQAIKSAAASLRYSDPDSVAVENISAAS"
FT   CDS             49640..49927
FT                   /transl_table=11
FT                   /gene="Mb2336"
FT                   /locus_tag="Mb2336"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2336, -, len: 95 aa. Equivalent to Rv2309A, len:
FT                   95 aa, from Mycobacterium tuberculosis strain H37Rv, (98.9%
FT                   identity in 95 aa overlap). Hypothetical unknown protein.
FT                   Equivalent to AAK46663 from Mycobacterium tuberculosis
FT                   strain CDC1551 (95 aa) but longer 13 aa."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU6"
FT                   /protein_id="CAD97197.1"
FT                   /translation="MATSSDDITINRHPPLNCAVNRHDESRRSPLRRGLLANGLRERQA
FT                   GALFERYKSQFDSFGYIEKVRYRGSGYRVEDVYARADSGPSAGAELPVGP"
FT   CDS             50030..50374
FT                   /transl_table=11
FT                   /gene="Mb2337"
FT                   /locus_tag="Mb2337"
FT                   /product="POSSIBLE EXCISIONASE"
FT                   /note="Mb2337, -, len: 114 aa. Equivalent to Rv2310, len:
FT                   114 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 114 aa overlap). Possible excisionase,
FT                   showing some similarity to others e.g. Q9LCU5 PUTATIVE
FT                   EXCISIONASE from Arthrobacter sp. TM1 (174 aa) FASTA
FT                   scores: opt: 341, E(): 6.6e-15, (48.2% identity in 110 aa
FT                   overlap); O85865 PUTATIVE EXCISIONASE from Sphingomonas
FT                   aromaticivorans (152 aa), FASTA scores: opt: 205, E():
FT                   2.2e-06, (41.25% identity in 80 aa overlap); etc. Also
FT                   similar to Rv3750c|O69717 HYPOTHETICAL PROTEIN from
FT                   Mycobacterium tuberculosis (130 aa), FASTA scores: opt:
FT                   228, E(): 6.9e-08, (43.9% identity in 82 aa overlap).
FT                   Contains possible helix-turn-helix motif at aa 20-41 (Score
FT                   2181, +6.62 SD)."
FT                   /db_xref="GOA:P64988"
FT                   /db_xref="InterPro:IPR010093"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64988"
FT                   /protein_id="CAD97198.1"
FT                   /translation="MVAALHAGKAVTIAPQSMTLTTQQAADLLGVSRPTVVRLIKSGEL
FT                   AAERIGNRHRLVLDDVLAYREARRQRQYDALAESAMDIDADEDPEVICEQLREARRVVA
FT                   ARRRTERRRA"
FT   CDS             50479..51003
FT                   /transl_table=11
FT                   /gene="Mb2338"
FT                   /locus_tag="Mb2338"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2338, -, len: 174 aa. Equivalent to Rv2311, len:
FT                   174 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 174 aa overlap). Conserved hypothetical
FT                   protein, with similarity (in part) to transfer proteins
FT                   homologous TRAA e.g. Q9EUN8|TRAA TRANSFER PROTEIN HOMOLOG
FT                   TRAA from Corynebacterium glutamicum (1160 aa), FASTA
FT                   scores: opt: 221, E(): 2.9e-07, (36.8% identity in 136 aa
FT                   overlap); Q9ETQ3|TRAA CONJUGAL TRANSFER PROTEIN (TRAA-LIKE
FT                   PROTEIN) from Corynebacterium equii (1367 aa), FASTA
FT                   scores: opt: 188, E(): 5.5e-05, (33% identity in 106 aa
FT                   overlap); P55418|TRAA_RHISN|Y4DS PROBABLE CONJUGAL TRANSFER
FT                   PROTEIN from Rhizobium sp. strain NGR234 (1102 aa), FASTA
FT                   scores: opt: 145, E(): 0.035, (29.08% identity in 141 aa
FT                   overlap); etc."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64990"
FT                   /protein_id="CAD97199.1"
FT                   /translation="MAPTGQAVDVAVREGAGDVGYSVERENLPADDPVRNGNRWRVIAV
FT                   DTEHHRIAARRLGDGARAAFSGDYLHEHITHGYAITVHASQGTTAHSTHAVLGDNTSRA
FT                   TLYVAMTPARESNTAYLCERTAGEGARVDLAGWDLWVSGKAEAMSDEKSASPVWCRVGA
FT                   RCDHRGKRSCW"
FT   CDS             51081..51350
FT                   /transl_table=11
FT                   /gene="Mb2339"
FT                   /locus_tag="Mb2339"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2339, -, len: 89 aa. Equivalent to Rv2312, len: 89
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 89 aa overlap). Hypothetical unknown protein."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64992"
FT                   /protein_id="CAD97200.1"
FT                   /translation="MMKEIELHLVDAAAPSGEIAIKDLAALATALQELTTRISRDPINT
FT                   PGPGRTKQFMEELSQLASAPGPDIDGGIDLTDDEFQAFLQAARS"
FT   CDS             complement(51647..52501)
FT                   /transl_table=11
FT                   /gene="Mb2340c"
FT                   /locus_tag="Mb2340c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2340c, -, len: 284 aa. Equivalent to Rv2313c, len:
FT                   284 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 284 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/Swiss-Prot:P64994"
FT                   /protein_id="CAD97201.1"
FT                   /translation="MPAPVSVRDDLCRLVALSPGDGRIAGLVRQVCARALSLPSLPCEV
FT                   AVNEPESPAEAVVAEFAEQFSVDVSAITGEQRSLLWTHLGEDAFGAVVAMYIADFVPRV
FT                   RAGLEALGVGKEYLGWVTGPISWDHNTDLSAAVFNGFLPAVARMRALDPVTSELVRLRG
FT                   AAQHNCRVCKSLREVSALDAGGSETLYGEIERFDTSVLLDVRAKAALRYADALIWTPAH
FT                   LAVDVAVEVRSRFSDDEAVELTFDIMRNASNKVAVSLGADAPRVQQGTERYRIGLDGQT
FT                   VFG"
FT   CDS             complement(52512..53885)
FT                   /transl_table=11
FT                   /gene="Mb2341c"
FT                   /locus_tag="Mb2341c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2341c, -, len: 457 aa. Equivalent to Rv2314c, len:
FT                   457 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 457 aa overlap). Conserved hypothetical
FT                   protein, highly similar to Q9RJ51|SCI8.02 HYPOTHETICAL
FT                   PROTEIN from Streptomyces coelicolor (464 aa) FASTA scores:
FT                   opt: 1485, E(): 5.2e-83, (53.5% identity in 454 aa
FT                   overlap); similar to AAK24788|CC2824 TldD/PmbA family
FT                   protein from Caulobacter crescentus (441 aa), FASTA scores:
FT                   opt: 364, E(): 8.3e-15, (29.8% identity in 460 aa overlap);
FT                   and showing similarity with Q9HJZ6|TA0814 HYPOTHETICAL
FT                   PROTEIN from Thermoplasma acidophilum (430 aa), FASTA
FT                   scores: opt: 220, E(): 4.7e-06, (21.85% identity in 348 aa
FT                   overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU5"
FT                   /protein_id="CAD97202.1"
FT                   /translation="MIEPQHAVNIVLKEAARSGRADETMVLVTEKVEATLRWAGNSMTT
FT                   NGVSHSRNVTVISIVRRGDSAFVGSVVSAEVDPSVLPGLVVSSQDAARSAPEAGDAAPL
FT                   LADTGEPDDWDAPVPGTGAGVFTGIAGSLSRGFRGADRLYGYAHRSVSTTFLASSTGLR
FT                   RRYTQPTGAIEINAKRGDASAWVGIGTPDFVEVPIDLMLERLSTRLRWAQRTVELPAGR
FT                   YQTIMPPSTVADMMIYLGWSMAGRGAQEGRTAFSAPGGGTRVGERLTELPLTLFTDPAA
FT                   PGLACTPFVAVSNSSETQSVFDNGMEISQVDWIRSGVINALAYPRATAAKFDAPVAVAA
FT                   DNLIMTGGSADLADMIAGTERGLLLTTLWYIREVDPTTLLLTGLTRDGVYLVEDGEVSA
FT                   AVNNFRFNESPLDLLRRATEAGVSEPTLPREWSDWVTRTAMPPLRIPDFHMSSVSQAQ"
FT   CDS             complement(53882..55399)
FT                   /transl_table=11
FT                   /gene="Mb2342c"
FT                   /locus_tag="Mb2342c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2342c, -, len: 515 aa. Equivalent to Rv2315c, len:
FT                   515 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 505 aa overlap). Conserved hypothetical
FT                   protein, highly similar to Q9S273|SCI28.10 HYPOTHETICAL
FT                   47.1 KDA PROTEIN from Streptomyces coelicolor (435 aa),
FT                   FASTA scores: opt: 1768, E():5.6e-101, (63.2% identity in
FT                   432 overlap); and similar to others e.g. AAK24787|CC2823
FT                   hypothetical protein (TldD/PmbA family) from Caulobacter
FT                   crescentus (543 aa), FASTA scores: opt: 876, E():3.1e-46,
FT                   (42.8% identity in 505 overlap); O58578|PH0848 HYPOTHETICAL
FT                   54.4 KDA PROTEIN from Pyrococcus horikoshii (481 aa), FASTA
FT                   scores: opt: 661, E(): 4.3e-33, (29.95% identity in 484 aa
FT                   overlap); Q9UZ95|PAB1547 HYPOTHETICAL 53.6 KDA PROTEIN from
FT                   Pyrococcus abyssi (473 aa), FASTA scores: opt: 656, E():
FT                   8.6e-33, (29.1% identity in 481 aa overlap); etc."
FT                   /db_xref="InterPro:IPR002510"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU4"
FT                   /protein_id="CAD97203.1"
FT                   /translation="MTPNRGIDEDFLDLPRQQLADAALSAAATAGASHADLRVHRISTE
FT                   IIQLRDGELETAVISRELGLAVRVIVAGTWGFASHAELAPDVAAATARHAVHVATVLAA
FT                   LNTERVRLAPEPVYTDAEWVSNYRIDPFGVPASEKIAVLRDYSGRLLDADGIDHVSASL
FT                   NAVKEQTFYADTFGSSITQQRVRLLPCLDAVAVDSAAGNFESMRTLAPPTARGWEVVAG
FT                   DEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDLVIDPTNLWLTIHESIGHATEYDRAIG
FT                   YEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTAEFGLATVGYDDEGVAAQSWDLVRDG
FT                   VFVGYQLDRAFAPRLGEPRSNGCSYADSPHHVPIQRMANISLQPGIEDLSTADLIGRVD
FT                   DGIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQLYGQLRDVAYQSSTTDFWNAMEAVG
FT                   GPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRGVNVLNTRTEGGR"
FT   CDS             55433..56305
FT                   /transl_table=11
FT                   /gene="uspA"
FT                   /locus_tag="Mb2343"
FT                   /product="PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN ABC TRANSPORTER USPA"
FT                   /note="Mb2343, uspA, len: 290 aa. Equivalent to Rv2316,
FT                   len: 290 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 290 aa overlap). Probable uspA,
FT                   sugar-transport integral membrane protein ABC transporter
FT                   (see citation below), most similar to Q9CBN8|USPA|ML1768
FT                   SUGAR TRANSPORT INTEGRAL MEMBRANE PROTEIN from
FT                   Mycobacterium leprae (328 aa), FASTA scores: opt: 1593,
FT                   E(): 1.9e-93, (82.35% identity in 289 aa overlap); and
FT                   similar to O32940|ML1426|MLCB2052.28 POSSIBLE SUGAR
FT                   TRANSPORT PROTEIN (PROBABLE ABC-TRANSPORT PROTEIN, INNER
FT                   MEMBRANE COMPONENT) from Mycobacterium leprae (319 aa),
FT                   FASTA scores: opt: 600, E(): 9.2e-31, (34.25% identity in
FT                   295 aa overlap). Also similar to other proteins involved in
FT                   transport e.g. Q9X860|SCE134.05c PUTATIVE BINDING PROTEIN
FT                   DEPENDENT TRANSPORT PROTEIN from Streptomyces coelicolor
FT                   (327 aa), FASTA scores: opt: 639, E(): 3.2e-33, (40.45%
FT                   identity in 272 aa overlap); Q9K6N9|BH3689 SUGAR TRANSPORT
FT                   SYSTEM (PERMEASE) from Bacillus halodurans (300 aa), FASTA
FT                   scores: opt: 590, E(): 3.7e-30, (35.65% identity in 289 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:Q7TYU3"
FT                   /db_xref="InterPro:IPR000515"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU3"
FT                   /protein_id="CAD97204.1"
FT                   /translation="MRDAPRRRTALAYALLAPSLVGVVAFLLLPILVVVWLSLHRWDLL
FT                   GPLRYVGLTNWRSVLTDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLF
FT                   RTLYVLPWICAPLAIAVMWRWILAPTDGAISTVLGHRIEWLTDPGLALPVVSAVVVWTN
FT                   VGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTMFFVLVTGIISAAQ
FT                   VFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRASVMAVVLFVILVGATVVQHLYF
FT                   RRRISYELT"
FT   CDS             56292..57116
FT                   /transl_table=11
FT                   /gene="uspB"
FT                   /locus_tag="Mb2344"
FT                   /product="PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN ABC TRANSPORTER USPB"
FT                   /note="Mb2344, uspB, len: 274 aa. Equivalent to Rv2317,
FT                   len: 274 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 274 aa overlap). Probable uspB,
FT                   sugar-transport integral membrane protein ABC transporter
FT                   (see citation below), most similar to Q9CBN7|USPE|ML1769
FT                   SUGAR TRANSPORT INTEGRAL MEMBRANE PROTEIN from
FT                   Mycobacterium leprae (274 aa), FASTA scores: opt: 1522,
FT                   E(): 3.4e-89, (85.0% identity in 274 aa overlap); and
FT                   similar to O32941|ML1425|MLCB2052.29 PROBABLE ABC-TRANSPORT
FT                   PROTEIN, INNER MEMBRANE COMPONENT from Mycobacterium leprae
FT                   (283 aa), FASTA scores: opt: 630, E(): 8.4e-33, (36.55%
FT                   identity in 268 aa overlap). Also similar to other integral
FT                   membrane proteins e.g. P73854|LACG|SLR1723 LACTOSE
FT                   TRANSPORT SYSTEM PERMEASE PROTEIN from Synechocystis sp.
FT                   strain PCC 6803 (270 aa), FASTA scores: opt: 605, E():
FT                   3.1e-31, (36.0% identity in 264 aa overlap);
FT                   Q9F3B8|SC5F1.11 PUTATIVE SUGAR TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN from Streptomyces coelicolor (307 aa), FASTA
FT                   scores: opt: 582, E(): 9.7e-30, (34.45% identity in 264 aa
FT                   overlap); etc. Also similar to O53483|Rv2039c|MTV018.26c
FT                   SUGAR TRANSPORT PROTEIN from Mycobacterium tuberculosis
FT                   (280 aa), FASTA scores: opt: 630, E(): 8.3e-89, (37.7%
FT                   identity in 268 aa overlap)."
FT                   /db_xref="GOA:Q7TYU2"
FT                   /db_xref="InterPro:IPR000515"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU2"
FT                   /protein_id="CAD97205.1"
FT                   /translation="MSSPSRVSNTAVYAVLTIGAVITLSPFLLGLLTSFTSAHQFATGT
FT                   PLQLPRPPTLANYADIADAGFRRAAVVTALMTAVILLGQLTFSVLAAYAFARLQFRGRD
FT                   ALFWVYVATLMVPGTVTVVPLYLMMAQLGLRNTFWALVLPFMFGSPYAIFLLREHFRLI
FT                   PDDLINAARLDGANTLDVIVHVVIPSSRPVLAALAMITVVSQWNNFMWPLVITSGHKWR
FT                   VLTVATADLQSRFNDQWTLVMAATTVAIVPLIALFVTFQRHIVASIVVSGLK"
FT   CDS             57113..58435
FT                   /transl_table=11
FT                   /gene="uspC"
FT                   /locus_tag="Mb2345"
FT                   /product="PROBABLE PERIPLASMIC SUGAR-BINDING LIPOPROTEIN
FT                   USPC"
FT                   /note="Mb2345, uspC, len: 440 aa. Equivalent to Rv2318,
FT                   len: 440 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 440 aa overlap). Probable uspC,
FT                   sugar-binding lipoprotein component of sugar transport
FT                   system (see citation below), most similar to
FT                   Q9CBN6|USPC|ML1770 SUGAR TRANSPORT PERIPLASMIC BINDING
FT                   PROTEIN from Mycobacterium leprae (446 aa), FASTA scores:
FT                   opt: 2294, E(): 8.1e-135, (74.7% identity in 446 aa
FT                   overlap). Also similar to other substrate-binding proteins
FT                   e.g. Q9RK89|SCF1.15 PUTATIVE SUBSTRATE BINDING PROTEIN
FT                   (EXTRACELLULAR) (BINDING-PROTEIN-DEPENDENT TRANSPORT)
FT                   (FRAGMENT) from Streptomyces coelicolor (221 aa), FASTA
FT                   scores: opt: 377, E(): 3e-16, (32.25% identity in 217 aa
FT                   overlap); Q9K6N8|BH3690 SUGAR TRANSPORT SYSTEM
FT                   (SUGAR-BINDING PROTEIN) from Bacillus halodurans (420 aa),
FT                   FASTA scores: opt: 227, E(): 1e-06, (25.00% identity in 452
FT                   aa overlap); etc. Also similar to O53485|Rv2041c|MTV018.28C
FT                   LIPOPROTEIN COMPONENT OF SUGAR TRANSPORT SYSTEM from
FT                   Mycobacterium tuberculosis (439 aa), FASTA scores: opt:
FT                   246, E(): 7e-08, (26.75% identity in 325 aa overlap).
FT                   Contains a hydrophobic stretch (possible signal peptide) at
FT                   N-terminal end."
FT                   /db_xref="GOA:Q7TYU1"
FT                   /db_xref="InterPro:IPR006059"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU1"
FT                   /protein_id="CAD97206.1"
FT                   /translation="MTRPRQSTLVATALVLVAILLGVTAVLLGLSAEPRGGKIVVTVRL
FT                   WDEPIAAAYRQSFAAFTRSHPDIEVRTNLVAYSTYFETLRTDVAGGSADDIFWLSNAYF
FT                   AAYADSGRLMKIQTDAADWEPAVVDQFTRSGVLWGVPQLTDAGIAVFYNADLLAAAGVD
FT                   PTQVDNLRWSRGDDDTLRPMLARLTVDADGRTANTPGFDARRVRQWGYNAANDPQAIYL
FT                   NYIGSAGGVFQRDGKFAFDNPGAIEAFRYLVGLINDDHVAPPASDTNDNGDFSRNQFLA
FT                   GKMALFQSGTYSLAPVARDALFHWGVAMLPAGPAGRVSVTNGIAAAGNSASKHPDAVRQ
FT                   VLAWMGSTEGNSYVGRHGAAIPAVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGG
FT                   AGFAAGQQALEPYFDEMFLGRGDVTTTLRQAQAAANAATQR"
FT   CDS             complement(58443..59321)
FT                   /transl_table=11
FT                   /gene="Mb2346c"
FT                   /locus_tag="Mb2346c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2346c, -, len: 292 aa. Equivalent to Rv2319c, len:
FT                   292 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 292 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="GOA:P64996"
FT                   /db_xref="InterPro:IPR006016"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64996"
FT                   /protein_id="CAD97207.1"
FT                   /translation="MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPS
FT                   LARVDAEYELWSEQLAAASAREAQRYLRRLADGIEVSYHHRAHRSVSAGLLDVVEELEA
FT                   EVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSATSG
FT                   SVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKL
FT                   RINGVVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIR
FT                   YSPVPVLVLPG"
FT   CDS             complement(59318..60748)
FT                   /transl_table=11
FT                   /gene="rocE"
FT                   /locus_tag="Mb2347c"
FT                   /product="PROBABLE CATIONIC AMINO ACID TRANSPORT INTEGRAL
FT                   MEMBRANE PROTEIN ROCE"
FT                   /note="Mb2347c, rocE, len: 476 aa. Equivalent to Rv2320c,
FT                   len: 476 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 476 aa overlap). Probable rocE,
FT                   cationic amino acid (especially arginine and ornithine)
FT                   transporter (permease), highly similar to other amino acid
FT                   transporters e.g. Q9L100|SCL6.16C PUTATIVE AMINO ACID
FT                   TRANSPORTER from Streptomyces coelicolor (496 aa), FASTA
FT                   scores: opt: 1485, E(): 9.4e-82, (48.4% identity in 477 aa
FT                   overlap); O06479|YFNA PUTATIVE AMINO ACID TRANSPORTER from
FT                   Bacillus subtilis (462 aa), FASTA scores: opt: 1271, E():
FT                   6.1e-69, (41.9% identity in 463 aa overlap); Q9PG94|XF0408
FT                   AMINO ACID TRANSPORTER from Xylella fastidiosa (509 aa),
FT                   FASTA scores: opt: 1128, E(): 2.5e-60, (39.5% identity in
FT                   481 aa overlap); etc. Also some similarity with
FT                   Z99108.1|BSUB0005 from Bacillus subtilis (461 aa), FASTA
FT                   scores: opt: 1271, E(): 0, (41.9% identity in 463 aa
FT                   overlap); and G403170 ETHANOLAMINE PERMEASE (488 aa), FASTA
FT                   scores: opt: 468, E(): 1e-23, (28.1% identity in 462 aa
FT                   overlap). SEEMS TO BELONG TO THE APC FAMILY."
FT                   /db_xref="GOA:Q7TYU0"
FT                   /db_xref="InterPro:IPR004841"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYU0"
FT                   /protein_id="CAD97208.1"
FT                   /translation="MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGV
FT                   GATIGTGIFFVLAQAVPEAGPGVIVSFIIAGIAAGLAAICYAELASAVPISGSAYSYAY
FT                   TTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHP
FT                   GWVNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDF
FT                   VPFGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVAL
FT                   AALGTQPWQDFAEQETAGLAIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRIL
FT                   FAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFS
FT                   VVAVGVIVLRVREPDLPRGFKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAV
FT                   IFYLMWGRHHSALNEEVP"
FT   CDS             complement(60749..61294)
FT                   /transl_table=11
FT                   /gene="rocD2"
FT                   /locus_tag="Mb2348c"
FT                   /product="PROBABLE ORNITHINE AMINOTRANSFERASE (C-terminus
FT                   part) ROCD2 (ORNITHINE--OXO-ACID AMINOTRANSFERASE)"
FT                   /EC_number="2.6.1.13"
FT                   /note="Mb2348c, rocD2, len: 181 aa. Equivalent to Rv2321c,
FT                   len: 181 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 181 aa overlap). Probable rocD2,
FT                   ornithine aminotransferase (EC: 2.6.1.13), highly similar
FT                   to C-terminal region of other ornithine aminotransferases,
FT                   e.g. Q9FC90|ROCD from Streptomyces coelicolor (407 aa),
FT                   FASTA scores: opt: 628, E(): 1.2e-32, (55.35% identity in
FT                   168 aa overlap); P3802|OAT_BACSU|ROCD from Bacillus
FT                   subtilis (401 aa), FASTA scores: opt: 477, E(): 4.3e-23,
FT                   (42.1% identity in 178 aa overlap); BAB42057|ROCD|SA0818
FT                   from Staphylococcus aureus subsp. aureus N315 (396 aa),
FT                   FASTA scores: opt: 437, E(): 1.5e-20, (41.3% identity in
FT                   170 aa overlap); etc. Contains PS00600 Aminotransferases
FT                   class-III pyridoxal-phosphate attachment site. BELONGS TO
FT                   CLASS-III OF PYRIDOXAL-PHOSPHATE-DEPENDENT
FT                   AMINOTRANSFERASES. Rv2322c|MTCY3G12.12 (upstream ORF) and
FT                   Rv2321c|MTCY3G12.13 appear to be an ornithine
FT                   aminotransferase homologue but are frameshifted - we can
FT                   find no sequence error in the cosmid to account for this."
FT                   /db_xref="GOA:Q7TYT9"
FT                   /db_xref="HSSP:1DKA"
FT                   /db_xref="InterPro:IPR015422"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT9"
FT                   /protein_id="CAD97209.1"
FT                   /translation="MIADEIQSGLACTGYPFACDHGGVLPDIYLLGKTLGGGAVPLSAM
FT                   VADREIFGVVHPGEHGSTFGGNPLAAAIGTPVVSMVVWGECQARSAKLGAHLHQRLADL
FT                   IGDGAVALRGLGWWADVDIERALAIGTDMSMRLADRGVLLKDTYGAALRFAPPLVITAQ
FT                   EIDCAVRRFADALWEAGS"
FT   CDS             complement(61294..61959)
FT                   /transl_table=11
FT                   /gene="rocD1"
FT                   /locus_tag="Mb2349c"
FT                   /product="PROBABLE ORNITHINE AMINOTRANSFERASE (N-terminus
FT                   part) ROCD1 (ORNITHINE--OXO-ACID AMINOTRANSFERASE)"
FT                   /EC_number="2.6.1.13"
FT                   /note="Mb2349c, rocD1, len: 221 aa. Equivalent to Rv2322c,
FT                   len: 221 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 221 aa overlap). Probable rocD1,
FT                   ornithine aminotransferase (EC: 2.6.1.13), highly similar
FT                   to N-terminal region of other ornithine aminotransferases,
FT                   e.g. Q9FC90|ROCD from Streptomyces coelicolor (407 aa),
FT                   FASTA scores: opt: 770, E(): 8.7e-40, (55.7% identity in
FT                   201 aa overlap); BAB42057|ROCD|SA0818 from Staphylococcus
FT                   aureus subsp. aureus N315 (396 aa) FASTA scores: opt: 632,
FT                   E(): 2.2e-31, (46.1% identity in 208 aa overlap);
FT                   P38021|OAT_BACSU|ROCD from Bacillus subtilis (401 aa),
FT                   FASTA scores: opt: 626, E(): 5.1e-31, (43.1% identity in
FT                   218 aa overlap); etc. BELONGS TO CLASS-III OF
FT                   PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES.
FT                   Rv2322c|MTCY3G12.12 and Rv2321c|MTCY3G12.13 (upstream ORF)
FT                   appear to be an ornithine aminotransferase homologue but
FT                   are frameshifted - we can find no sequence error in the
FT                   cosmid to account for this."
FT                   /db_xref="GOA:Q7TYT8"
FT                   /db_xref="HSSP:1GBN"
FT                   /db_xref="InterPro:IPR015421"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT8"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97210.1"
FT                   /translation="MTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLR
FT                   YLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVV
FT                   LPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGS
FT                   GVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC"
FT   CDS             complement(61956..62864)
FT                   /transl_table=11
FT                   /gene="Mb2350c"
FT                   /locus_tag="Mb2350c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2350c, -, len: 302 aa. Equivalent to Rv2323c, len:
FT                   302 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 302 aa overlap). Conserved hypothetical
FT                   protein, highly similar to others eg Q9FC91|2SCG58.22
FT                   CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor
FT                   (288 aa), FASTA scores: opt: 561, E(): 7.3e-28, (46.95%
FT                   identity in 279 aa overlap); P74535|SLL1336 HYPOTHETICAL
FT                   78.3 KDA PROTEIN from Synechocystis sp. (705 aa), FASTA
FT                   scores: opt: 555, E(): 2.1e-27, (37.75% identity in 265 aa
FT                   overlap); etc. Also similar to various hydrolases e.g.
FT                   Q53797 BETA-HYDROXYLASE (BLEOMYCIN/PHLEOMYCIN BINDING
FT                   PROTEIN, ANKYRIN HOMOLOGUE, BLEOMYCIN AND TRANSPORT
FT                   PROTEIN) from Streptomyces verticillus (326 aa), FASTA
FT                   scores: opt: 211, E(): 4.5e-06, (26.75% identity in 303 aa
FT                   overlap); Q9X7M4|DDAH_STRCO|SC5F2A.01c
FT                   NG,NG-dimethylarginine dimethylaminohydrolase (EC 3.5.3.18)
FT                   (Dimethylargininase) (Dimethylarginine
FT                   dimethylaminohydrolase) (258 aa), FASTA scores: opt: 209,
FT                   E(): 4.9e-06, (27.15% identity in 243 aa overlap); G434715
FT                   beta-hydroxylase (bleomicin/phleomycin binding protein)
FT                   from Streptomyces verticillus (326 aa), FASTA scores: opt:
FT                   211, E(): 4.5e-06, (26.75% identity in 303 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:Q7TYT7"
FT                   /db_xref="InterPro:IPR003198"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97211.1"
FT                   /translation="MENTQRPSFDCEIRAKYRWFMTDSYVAAARLGSPARRTPRTRRYA
FT                   MTPPAFFAVAYAINPWMDVTAPVDVQVAQAQWEHLHQTYLRLGHSVDLIEPISGLPDMV
FT                   YTANGGFITHDIAVVARFRFPERAGESRAYASWMSSVGYRPVTTRHVNEGQGDLLMVGE
FT                   RVLAGYGFRTDQRAHAEIAAVLGLPVVSLELVDPRFYHLDTALAVLDDHTIAYYPPAFS
FT                   TAAQEQLSALFPDAIVVGSADAFVFGLNAVSDGLNVVLPVAAMGFAAQLRAAGFEPVGV
FT                   DLSELLKGGGSVKCCTLEIHP"
FT   CDS             62929..63375
FT                   /transl_table=11
FT                   /gene="Mb2351"
FT                   /locus_tag="Mb2351"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
FT                   (PROBABLY ASNC-FAMILY)"
FT                   /note="Mb2351, -, len: 148 aa. Equivalent to Rv2324, len:
FT                   148 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 148 aa overlap). Probable
FT                   transcriptional regulatory protein, asnC-family, similar to
FT                   other PUTATIVE ASNC-FAMILY REGULATORY PROTEINS e.g.
FT                   Q9L101|SCL6.15C from Streptomyces coelicolor (150 aa) FASTA
FT                   scores: opt: 466, E(): 2.4e-24, (52.8% identity in 142 aa
FT                   overlap); Q9RKY4|SC6D7.14 PUTATIVE ASNC-FAMILY
FT                   TRANSCRIPTIONAL REGULATORY PROTEIN from Streptomyces
FT                   coelicolor (165 aa), FASTA scores: opt: 266, E(): 5.5e-11,
FT                   (32.4% identity in 145 aa overlap); Q9ZEP1|LRPA|SCE94.12c
FT                   PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces
FT                   coelicolor (150 aa), FASTA scores: opt: 249, E(): 6.9e-10,
FT                   (33.35% identity in 147 aa overlap); etc. Also similar to
FT                   P96896|Rv3291c|MTCY71.31c from Mycobacterium tuberculosis
FT                   (150 aa), FASTA scores: opt: 261, E(): 1.1e-10, (36.4%
FT                   identity in 143 aa overlap)."
FT                   /db_xref="GOA:Q7TYT6"
FT                   /db_xref="InterPro:IPR019888"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT6"
FT                   /protein_id="CAD97212.1"
FT                   /translation="MDRLDDTDERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRML
FT                   ESGVIKGFTTVVDRNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAATVTGTSD
FT                   AILHVLAHDMRHLEAALERIRSSADVERSESTVVLSNLIDRMPP"
FT   CDS             complement(63604..64452)
FT                   /transl_table=11
FT                   /gene="Mb2352c"
FT                   /locus_tag="Mb2352c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2352c, -, len: 282 aa. Equivalent to Rv2325c, len:
FT                   282 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 282 aa overlap). Conserved hypothetical
FT                   protein, equivalent to O32970|MLCB22.37c|ML0849
FT                   hypothetical protein from Mycobacterium leprae (283 aa),
FT                   FASTA scores: opt: 1405, E(): 1.8e-78, (77.7% identity in
FT                   282 aa overlap). Also some similarity to other proteins
FT                   e.g. Q9Z9J1|YBAF|BH0166 YBAF PROTEIN (BH0166 PROTEIN)
FT                   (HYPOTHETICAL PROTEIN) from Bacillus halodurans (265 aa),
FT                   FASTA scores: opt: 288, E(): 2.8e-10, (25.8% identity in
FT                   264 aa overlap); P70972|YBAF YBAF PROTEIN (HYPOTHETICAL
FT                   PROTEIN) from Bacillus subtilis (265 aa), FASTA scores:
FT                   opt: 259, E(): 1.5e-08, (25.45% identity in 224 aa
FT                   overlap); AAK34821|SPY2193|Q99X13 Conserved hypothetical
FT                   protein from Streptococcus pyogenes (266 aa), FASTA scores:
FT                   opt: 232, E(): 6.5e-07, (25.1% identity in 267 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:P64998"
FT                   /db_xref="InterPro:IPR003339"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64998"
FT                   /protein_id="CAD97213.1"
FT                   /translation="MTTTSAPARNGTRRPSRPIVLLIPVPGSSVIHDLWAGTKLLVVFG
FT                   ISVLLTFYPGWVTIGMMAALVLAAARIAHIPRGALPSVPRWLWIVLAIGFLTAALAGGT
FT                   PVVAVGGVQLGLGGALHFLRITALSVVLLALGAMVSWTTNVAEISPAVATLGRPFRVLR
FT                   IPVDEWAVALALALRAFPMLIDEFQVLYAARRLRPKRMPPSRKARRQRHARELIDLLAA
FT                   AITVTLRRADEMGDAITARGGTGQLSAHPGRPKLADWVTLAITAMASGTAVAIESLILH
FT                   S"
FT   CDS             complement(64449..66542)
FT                   /transl_table=11
FT                   /gene="Mb2353c"
FT                   /locus_tag="Mb2353c"
FT                   /product="PUTATIVE TRANSMEMBRANE ATP-BINDING PROTEIN ABC
FT                   TRANSORTER"
FT                   /note="Mb2353c, -, len: 697 aa. Equivalent to Rv2326c, len:
FT                   697 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 697 aa overlap). Putative transmembrane
FT                   ATP-binding protein ABC transporter (see citation below).
FT                   Equivalent to Q9CCF9|ML0848 ABC TRANSPORTER from
FT                   Mycobacterium leprae (724 aa), FASTA scores: opt: 3482,
FT                   E(): 2.8e-182, (76.9% identity in 697 aa overlap) and also
FT                   to O32971|MLCB22.38c ABC-TYPE TRANSPORTER from
FT                   Mycobacterium leprae (726 aa), FASTA scores: opt: 3482,
FT                   E(): 2.8e-182, (76.9% identity in 697 aa overlap). Similar
FT                   in part to other ABC TRANSPORTERS e.g. Q9WY65|TM0222 from
FT                   Thermotoga maritima (266 aa), FASTA scores: opt: 407, E():
FT                   4.2e-15, (38.0% identity in 213 aa overlap); etc. Contains
FT                   2 X PS00017 ATP/GTP-binding site motif A (P-loop); and 2 x
FT                   PS00211 ABC transporters family signature. BELONGS TO THE
FT                   ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS)."
FT                   /db_xref="GOA:P63400"
FT                   /db_xref="HSSP:1L2T"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63400"
FT                   /protein_id="CAD97214.1"
FT                   /translation="MCCAVCGPEPGRIGEVTPLGPCPAQHRGGPLRPSELAQASVMAAL
FT                   CAVTAIISVVVPFAAGLALLGTVPTGLLAYRYRLRVLAAATVAAGMIAFLIAGLGGFMG
FT                   VVHSAYIGGLTGIVKRRGRGTPTVVVSSLIGGFVFGAAMVGMLAAMVRLRHLIFKVMTA
FT                   NVDGIAATLARMHMQGAAADVKRYFAEGLQYWPWVLLGYFNIGIMIVSLIGWWALSRLL
FT                   ERMRGIPDVHKLDPPPGDDVDALIGPVPVRLDKVRFRYPRAGQDALREVSLDVRAGEHL
FT                   AIIGANGSGKTTLMLILAGRAPTSGTVDRPGTVGLGKLGGTAVVLQHPESQVLGTRVAD
FT                   DVVWGLPLGTTADVGRLLSEVGLEALAERDTGSLSGGELQRLALAAALAREPAMLIADE
FT                   VTTMVDQQGRDALLAVLSGLTQRHRTALVHITHYDNEADSADRTLSLSDSPDNTDMVHT
FT                   AAMPAPVIGVDQPQHAPALELVGVGHEYASGTPWAKTALRDINFVVEQGDGVLIHGGNG
FT                   SGKSTLAWIMAGLTIPTTGACLLDGRPTHEQVGAVALSFQAARLQLMRSRVDLEVASAA
FT                   GFSASEQDRVAAALTVVGLDPALGARRIDQLSGGQMRRVVLAGLLARAPRALILDEPLA
FT                   GLDAASQRGLLRLLEDLRRARGLTVVVVSHDFAGMEELCPRTLHLRDGVLESAAASEAG
FT                   GMS"
FT   CDS             66583..67074
FT                   /transl_table=11
FT                   /gene="Mb2354"
FT                   /locus_tag="Mb2354"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2354, -, len: 163 aa. Equivalent to Rv2327, len:
FT                   163 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 163 aa overlap). Conserved hypothetical
FT                   protein, similar to Z80775|MTCY21D4.05c|Rv0042c from
FT                   Mycobacterium tuberculosis (208 aa), FASTA scores: opt:
FT                   242, E(): 5e-08, (43.0% identity in 107 aa overlap). Also
FT                   slight similarity to putative transcriptional regulatory
FT                   proteins belonging to the MARR-FAMILY e.g. Q9CCY2/ML2696
FT                   from Mycobacterium leprae (243 aa), FASTA scores: opt: 245,
FT                   E(): 3.7e-08, (35.35% identity in 150 aa overlap);
FT                   Q9L135|SC6D11.20 from Streptomyces coelicolor (155 aa),
FT                   FASTA scores: opt: 242, E(): 3.9e-08, (34.75% identity in
FT                   141 aa overlap); etc."
FT                   /db_xref="GOA:Q7TYT5"
FT                   /db_xref="InterPro:IPR000835"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT5"
FT                   /protein_id="CAD97215.1"
FT                   /translation="MSPSPAAANRSEVGGPLPGLGADLLAVVARLNRLATQRIQMPLPA
FT                   AQARLLATIEAQGEARIGDLAAVDHCSQPTMTTQVRRLEDAGLVTRTADPGDARAVRIR
FT                   ITPEGIRTLTAVRADRAAAIEPQLALLPPADRRVLADAVDVLRRLLDHAATTPGRATRQ
FT                   "
FT   CDS             67326..68474
FT                   /transl_table=11
FT                   /gene="PE23"
FT                   /locus_tag="Mb2355"
FT                   /product="PE FAMILY PROTEIN"
FT                   /note="Mb2355, PE23, len: 382 aa. Equivalent to Rv2328,
FT                   len: 382 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 382 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PE family, similar to others
FT                   e.g. Q9L8K5|MAG24-1 PE-PGRS HOMOLOG from Mycobacterium
FT                   marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18,
FT                   (34.65% identity in 401 aa overlap); etc."
FT                   /db_xref="GOA:P0A685"
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A685"
FT                   /protein_id="CAD97216.1"
FT                   /translation="MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAED
FT                   EVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVN
FT                   APARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSA
FT                   GAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVV
FT                   GVVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLF
FT                   SPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNH
FT                   TMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS"
FT   CDS             complement(68509..70056)
FT                   /transl_table=11
FT                   /gene="narK1"
FT                   /locus_tag="Mb2356c"
FT                   /product="PROBABLE NITRITE EXTRUSION PROTEIN 1 NARK1
FT                   (NITRITE FACILITATOR 1)"
FT                   /note="Mb2356c, narK1, len: 515 aa. Equivalent to Rv2329c,
FT                   len: 515 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 515 aa overlap). Probable narK1,
FT                   nitrite extrusion protein, possibly member of major
FT                   facilitator superfamily (MFS). Equivalent to
FT                   O32974|MLCB22.41c|NARK|ML0844 PUTATIVE NITRITE EXTRUSION
FT                   PROTEIN from Mycobacterium leprae (517 aa), FASTA scores:
FT                   opt: 2224, E(): 1.9e-129, (69.3% identity in 488 aa
FT                   overlap). Also highly similar to others e.g. P94933 NITRITE
FT                   EXTRUSION PROTEIN from Mycobacterium fortuitum (471 aa),
FT                   FASTA scores: opt: 1969, E(): 8.6e-114, (62.1% identity in
FT                   459 aa overlap); P37758|NARU_ECOLI NITRITE EXTRUSION
FT                   PROTEIN 2 from Escherichia coli strain K12 (462 aa), FASTA
FT                   scores: opt: 792, E(): 2.3e-41, (36.95% identity in 476 aa
FT                   overlap); P10903|NARK_ECOLI nitrite extrusion protein
FT                   (nitrite facilitator 1) from Escherichia coli strain K12
FT                   (463 aa), FASTA scores: opt: 784, E(): 7e-41, (35.3%
FT                   identity in 468 aa overlap); etc. Also similar to
FT                   RV0261c|Z86089|MTCY6A4_5 from Mycobacterium tuberculosis
FT                   (469 aa), FASTA scores: opt: 2000, E(): 1.1e-115, (62.6%
FT                   identity in 470 aa overlap). BELONGS TO THE NARK/NASA
FT                   FAMILY OF TRANSPORTERS."
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT4"
FT                   /protein_id="CAD97217.1"
FT                   /translation="MEQHTLLQREESPRSPAAPSLRRLGGSRHITHWDPEDLGAWEAGN
FT                   KGIARRNLLWSVVTVHLGYSVWTLWPVLELLMPQDVYGFSTSDKFLLGTIATLFGAFLR
FT                   MPYALASAIFGGRNWATFSAIVLLIPAIGTTVLLTHPGLPLWPYLVCAALTGLGGGNFA
FT                   SSMSNANAFYPHRLKGSALGIAGGVGNLGVPAIQLVGLLAIATVGERKPYLVCALYVVL
FT                   VAIAVIGVSLFMNNVEQHRVQVNRLRPIVSAVLSTRDTWLLSLLYLGTFGSFIGFSFVF
FT                   GQVLQTNFLACGQSPARATLHAVELAFVGPLLAAVARIYGGRLADRVGGSRLTLIVFVA
FT                   MTLAAGLLISASTLEGRHVGQHRGATMVGYFVCFVALFVLSGLGNGSVYKMIPTIFEAC
FT                   SRSLDLSEAERRDWSRIISGVVIGFVAAFGALGGVGINMALRESYLSTGSGTDAFWIFM
FT                   MCYAAAAVLTWKVYDRRTVTDMGMLQAALVRQPASTPAELIGPRTQSDRFSGCSISA"
FT   CDS             complement(70290..70817)
FT                   /transl_table=11
FT                   /gene="lppP"
FT                   /locus_tag="Mb2357c"
FT                   /product="PROBABLE LIPOPROTEIN LPPP"
FT                   /note="Mb2357c, lppP, len: 175 aa. Equivalent to Rv2330c,
FT                   len: 175 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 175 aa overlap). Probable lppP,
FT                   lipoprotein. Contains signal sequence and appropriately
FT                   positioned PS00013 Prokaryotic membrane lipoprotein lipid
FT                   attachment site."
FT                   /db_xref="GOA:P65303"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65303"
FT                   /protein_id="CAD97218.1"
FT                   /translation="MRRQRSAVPILALLALLALLALIVGLGASGCAWKPPTTRPSPPNT
FT                   CKDSDGPTADTVRQAIAAVPIVVPGSKWVEITRGHTRNCRLHWVQIIPTIASQSTPQQL
FT                   LFFDRNIPLGSPTRNPKPYITVLPAGDDTVTVQYQWQIGSDQECCPTGIGTVRFHIGSD
FT                   GKLEALGSIPHQ"
FT   CDS             70892..71278
FT                   /transl_table=11
FT                   /gene="Mb2358"
FT                   /locus_tag="Mb2358"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2358, -, len: 128 aa. Equivalent to Rv2331, len:
FT                   128 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 128 aa overlap). Hypothetical unknown
FT                   protein; shortened version of MTCY3G12.03c to eliminate
FT                   overlap with MTCY3G12.04."
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5G4"
FT                   /protein_id="CAD97219.1"
FT                   /translation="MPPVFLPQIGRLTPDAVGEAIGIAADDIPMAARWIGSRPCSLIGQ
FT                   PNTMGDEMGYLGPGLAGQRCVDRLVMGASRSTCSRLPVIASVDERLSVLKPVRPRLHSI
FT                   SFIFKGRPGEVYLTVTGYNFRGVP"
FT   CDS             71335..71673
FT                   /transl_table=11
FT                   /gene="Mb2359"
FT                   /locus_tag="Mb2359"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2359, -, len: 112 aa. Equivalent to Rv2331A, len:
FT                   112 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.1% identity in 112 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT3"
FT                   /protein_id="CAD97220.1"
FT                   /translation="MKGHLATFGHPALPTYRGSWLSREPGSPYRLPAGAGRDRGDACRR
FT                   LPRRTGSGTLLRPGQRCTFAANADPMAKGVDRALCEIVAERRQLDLDLAKAQVRSALAN
FT                   QRYHRDVH"
FT   CDS             71703..73349
FT                   /transl_table=11
FT                   /gene="mez"
FT                   /locus_tag="Mb2360"
FT                   /product="PROBABLE [NAD] DEPENDENT MALATE OXIDOREDUCTASE
FT                   MEZ (MALIC ENZYME) (NAD-MALIC ENZYME) (MALATE DEHYDROGENASE
FT                   (OXALOACETATE DECARBOXYLATING)) (PYRUVIC-MALIC CARBOXYLASE)
FT                   (NAD-ME)"
FT                   /EC_number="1.1.1.38"
FT                   /note="Mb2360, mez, len: 548 aa. Equivalent to Rv2332, len:
FT                   548 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 548 aa overlap). Probable mez, malate
FT                   oxidoreductase [NAD] dependant (EC 1.1.1.38) (malic
FT                   enzyme), highly similar to others e.g. O34389|MALS PUTATIVE
FT                   MALOLACTIC ENZYME [INCLUDES: MALIC ENZYME (EC 1.1.1.-);
FT                   L-LACTATE DEHYDROGENASE (EC 1.1.1.27)] from Bacillus
FT                   subtilis (566 aa), FASTA scores: opt: 1927, E(): 5.5e-111,
FT                   (52.9% identity in 539 aa overlap); P45868|MAO2_BACSU|YWKA
FT                   PROBABLE NAD-DEPENDENT MALIC ENZYME from Bacillus subtilis
FT                   (582 aa), FASTA scores: opt: 1849, E(): 3.6e-106, (50.45%
FT                   identity in 543 aa overlap); Q48796|MLES_OENOE MALOLACTIC
FT                   ENZYME from Oenococcus oeni (541 aa), FASTA scores: opt:
FT                   1540, E(): 3.6e-87, (44.2% identity in 536 aa overlap);
FT                   etc. BELONGS TO THE MALIC ENZYMES FAMILY. N-terminus
FT                   shortened since first submission (previously 652 aa)."
FT                   /db_xref="GOA:Q7TYT2"
FT                   /db_xref="HSSP:1O0S"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT2"
FT                   /protein_id="CAD97221.1"
FT                   /translation="MSDARVPRIPAALSAPSLNRGVGFTHAQRRRLGLTGRLPSAVLTL
FT                   DQQAERVWHQLQSLATDLGRNLLLEQLHYRHEVLYFKVLADHLPELMPVVYTPTVGEAI
FT                   QRFSDEYRGQRGLFLSIDEPDEIEEAFNTLGLGPEDVDLIVCTDAEAILGIGDWGVGGI
FT                   QIAVGKLALYTAGGGVDPRRCLAVSLDVGTDNEQLLADPFYLGNRHARRRGREYDEFVS
FT                   RYIETAQRLFPRAILHFEDFGPANARKILDTYGTDYCVFNDDMQGTGAVVLAAVYSGLK
FT                   VTGIPLRDQTIVVFGAGTAGMGIADQIRDAMVADGATLEQAVSQIWPLDRPGLLFDDMD
FT                   DLRDFQVPYAKNRHQLGVAVGDRVGLSDAIKIASPTILLGCSTVYGAFTKEVVEAMTAS
FT                   CKHPMIFPLSNPTSRMEAIPADVLAWSNGRALLATGSPVAPVEFDETTYVIGQANNVLA
FT                   FPGIGLGVIVAGARLITRRMLHAAAKAIAHQANPTNPGDSLLPDVQNLRAISTTVAEAV
FT                   YRAAVQDGVASRTHDDVRQAIVDTMWLPAYD"
FT   CDS             complement(73346..74917)
FT                   /transl_table=11
FT                   /gene="Mb2361c"
FT                   /locus_tag="Mb2361c"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT
FT                   PROTEIN"
FT                   /note="Mb2361c, -, len: 523 aa. Equivalent to Rv2333c, len:
FT                   537 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 508 aa overlap). Probable conserved
FT                   integral membrane transport protein, member of major
FT                   facilitator superfamily (MFS) possibly involved in
FT                   transport of drug, highly similar to many e.g.
FT                   Q9RL22|C5G9.04c PUTATIVE TRANSMEMBRANE EFFLUX PROTEIN from
FT                   Streptomyces coelicolor (489 aa), FASTA scores: opt: 1031,
FT                   E(): 4e-55, (37.4% identity in 412 aa overlap);
FT                   Q9L0L9|SCD82.12 PUTATIVE TRANSMEMBRANE EFFLUX PROTEIN from
FT                   Streptomyces coelicolor (490 aa), FASTA scores: opt: 883,
FT                   E(): 3.8e-46, (36.35% identity in 407 aa overlap);
FT                   Q9ZBW5|SC4B5.03c PUTATIVE INTEGRAL MEMBRANE EFFLUX PROTEIN
FT                   from Streptomyces coelicolor (504 aa), FASTA scores: opt:
FT                   899, E(): 4.1e-47, (37.4% identity in 415 aa overlap);
FT                   P39886|TCMA_STRGA tetracenomycin C resistance and export
FT                   protein from Streptomyces glaucescens (538 aa), FASTA
FT                   scores: opt: 839, E(): 1.9e-43, (32.3% identity in 489 aa
FT                   overlap); etc. Also highly similar to
FT                   Rv2459|O53186|MTV008.15 PROBABLE CONSERVED INTEGRAL
FT                   MEMBRANE TRANSPORT PROTEIN from Mycobacterium tuberculosis
FT                   strain H37Rv (508 aa), FASTA scores: opt: 1385, E():
FT                   1.5e-76, (44.05% identity in 504 aa overlap); and
FT                   AAK46834|MT2534 DRUG TRANSPORTER from Mycobacterium
FT                   tuberculosis strain CDC1551 (523 aa), FASTA scores: opt:
FT                   1385, E(): 1.5e-76, (44.4% identity in 504 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
FT                   single base insertion (*-g) leads to a slightly longer
FT                   product with a different COOH part compared to its homolog
FT                   in Mycobacterium tuberculosis strain H37Rv (523 aa versus
FT                   537 aa)."
FT                   /db_xref="GOA:Q7TYT1"
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT1"
FT                   /protein_id="CAD97222.1"
FT                   /translation="MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQ
FT                   WVVASYSLGMAVFIMSAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGA
FT                   QGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRS
FT                   IFYVNLPMGALVLFLTLCYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWT
FT                   SVQTIVMLWTAAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLL
FT                   LTTQFLQNVRGYTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGL
FT                   LMLIFSEHRSSALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIG
FT                   STIGFAVLGSVLAAWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRH
FT                   IEHRDPVAIAEEDFIEGIRVALLVATATLAVVFLAGWRWFPRDVQTAGSDAKREAAYSD
FT                   DRRVRG"
FT   CDS             75392..76324
FT                   /transl_table=11
FT                   /gene="cysK1"
FT                   /locus_tag="Mb2362"
FT                   /product="PROBABLE CYSTEINE SYNTHASE A CYSK1
FT                   (O-ACETYLSERINE SULFHYDRYLASE A) (O-ACETYLSERINE
FT                   (THIOL)-LYASE A) (CSASE A)"
FT                   /EC_number="2.5.1.47"
FT                   /note="Mb2362, cysK1, len: 310 aa. Equivalent to Rv2334,
FT                   len: 310 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 310 aa overlap). Probable cysK1,
FT                   cysteine synthase A (EC 4.2.99.8), equivalent to
FT                   O32978|CYSK_MYCLE|ML0839|MLCB22.47 CYSTEINE SYNTHASE A from
FT                   Mycobacterium leprae (310 aa), FASTA scores: opt: 1756,
FT                   E(): 8.6e-96, (85.8% identity in 310 aa overlap). Also
FT                   highly similar to other CYSTEINE SYNTHASES e.g.
FT                   Q9JQL6|CYSK|NMA0974|NMB0763 PUTATIVE CYSTEINE SYNTHASE from
FT                   Neisseria meningitidis (serogroup A and B) (310 aa), FASTA
FT                   scores: opt: 1368, E(): 4.6e-73, (66.45% identity in 310 aa
FT                   overlap); P73410|CYSK_SYNY3|SLR1842 from Synechocystis sp
FT                   (312 aa), FASTA scores: opt: 1310, E(): 1.2e-69, (64.65%
FT                   identity in 311 aa overlap);
FT                   Q43725|CYSM_ARATH|OASC|ACS1|AT3G59760|F24G16.30 CYSTEINE
FT                   SYNTHASE (MITOCHONDRIAL PRECURSOR) from Arabidopsis
FT                   thaliana (Mouse-ear cress) (424 aa), FASTA scores: opt:
FT                   1253, E(): 3.2e-66, (59.2% identity in 309 aa overlap) (has
FT                   its N-terminus longer 104 aa); etc. Contains PS00901
FT                   Cysteine synthase/cystathionine beta-synthase P-phosphate
FT                   attachment site. BELONGS TO THE CYSTEINE
FT                   SYNTHASE/CYSTATHIONINE BETA-SYNTHASE FAMILY. Note that
FT                   previously known as cysK."
FT                   /db_xref="GOA:P0A535"
FT                   /db_xref="HSSP:1OAS"
FT                   /db_xref="InterPro:IPR001926"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A535"
FT                   /protein_id="CAD97223.1"
FT                   /translation="MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKD
FT                   RIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRM
FT                   LLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVW
FT                   RDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQG
FT                   IGAGFVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRP
FT                   ENAGKLIVVVLPDFGERYLSTPLFADVAD"
FT   CDS             76328..77017
FT                   /transl_table=11
FT                   /gene="cysE"
FT                   /locus_tag="Mb2363"
FT                   /product="PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT)"
FT                   /EC_number="2.3.1.30"
FT                   /note="Mb2363, -, len: 229 aa. Equivalent to Rv2335, len:
FT                   229 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 229 aa overlap). Probable cysE, serine
FT                   acetyltransferase (EC 2.3.1.30), equivalent to
FT                   O32979|CYSE|ML0838 SERINE ACETYLTRANSFERASE from
FT                   Mycobacterium leprae (227 aa), FASTA scores: opt: 1152,
FT                   E(): 9.6e-62, (76.4% identity in 229 aa overlap). Also
FT                   highly similar, except in C-terminal part, to others e.g.
FT                   Q9HXI6|CYSE|PA3816 O-ACETYLSERINE SYNTHASE from Pseudomonas
FT                   aeruginosa (258 aa), FASTA scores: opt: 737, E(): 6e-37,
FT                   (61.3% identity in 168 aa overlap); P23145|NIFP_AZOCH
FT                   PROBABLE SERINE ACETYLTRANSFERASE from Azotobacter
FT                   chroococcum mcd 1 (269 aa), FASTA scores: opt: 718, E():
FT                   8.4e-36, (55.45% identity in 220 aa overlap);
FT                   Q06750|CYSE_BACSU SERINE ACETYLTRANSFERASE from Bacillus
FT                   subtilis (217 aa), FASTA scores: opt: 640, E(): 3.1e-31,
FT                   (48.0% identity in 200 aa overlap); etc. Contains PS00101
FT                   Bacterial hexapeptide-repeat containing-transferases
FT                   signature. BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF
FT                   ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF
FT                   [LIV]-G-X(4)."
FT                   /db_xref="GOA:Q7TYT0"
FT                   /db_xref="InterPro:IPR001451"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYT0"
FT                   /protein_id="CAD97224.1"
FT                   /translation="MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLW
FT                   QRGARLLARAAAEFTRILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGV
FT                   TLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGV
FT                   PGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIW
FT                   HGEDFSI"
FT   CDS             77433..78401
FT                   /transl_table=11
FT                   /gene="Mb2364"
FT                   /locus_tag="Mb2364"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2364, -, len: 322 aa. Equivalent to Rv2336, len:
FT                   322 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 322 aa overlap). Hypothetical unknown
FT                   protein (see second citation below)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97225.1"
FT                   /translation="MDVPHEQPALSSSKSNRFTSQRQTTGVGTTTVERLEPRLSPASRH
FT                   ITEAKAFGTECHVSSFTREQDPDRAVRVEQIHGEAYVAAGHVYESALDELGRLDNSNAE
FT                   FILDKARGSTRETEVIYLHAVPAEPLSGSQGEGGLRIVGISAVGSIDDLSAFKAAKPSM
FT                   GLAHQRKLYDAIEDLGHGGVKEIAALSVTADAPPTVSYSLIREVLRLYHRTGEKLIITF
FT                   AMPAYAKMVMNFGRFAMPQVGEPFYAHRNNDPRTSNDLLLVPSIVEPSNFLENISRGVV
FT                   TADDGPTARRRFATLCYMTDGLDDYFMPLTRQVLSEGIQDI"
FT   CDS             complement(78465..79583)
FT                   /transl_table=11
FT                   /gene="Mb2365c"
FT                   /locus_tag="Mb2365c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2365c, -, len: 372 aa. Equivalent to Rv2337c, len:
FT                   372 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 372 aa overlap). Hypothetical unknown
FT                   protein, sharing some similarity with Q9RI33|SCJ12.27c
FT                   HYPOTHETICAL 37.2 KDA PROTEIN from Streptomyces coelicolor
FT                   (335 aa), BLAST scores: 134 AND 46, (28% AND 33% identity,
FT                   52% AND 44% positive); FASTA scores: opt: 176, E():
FT                   0.00042, (31.95% identity in 355 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS8"
FT                   /protein_id="CAD97226.1"
FT                   /translation="MRAGRWGPGMTGLDPAEFLSLVEAAALAPSADNRREVQLEHAGRR
FT                   VRLWGDQTWRSAPEHRRIMSLVAIGAAVENVKLRAGRLGFETKVCWFPDSGNPGLVAEI
FT                   DVDRLPQTRVDPIEVAIERRRTNRRVRFRGPPLSQGELGALSAEATGIDGIQLHWFDSP
FT                   ETRKQILRLVRLAETERFRSRELHEELFSAVRFDIGWTASSDDGLPPGSLEVEAWMRPM
FT                   FRGLRHWRVLRLLRTVGMHHALGLRAAYLPCRLAPHVGALTTSLDLASGALTAGAVFER
FT                   IWLRTTLLGAELQPFAASAVLSLPACEWVAPHVRAALVGGWNLLAPGHWPMMVFRIGHA
FT                   RAPSVRTMRQSVEAYCYAPAERSGSDSESRFA"
FT   CDS             complement(79703..80659)
FT                   /transl_table=11
FT                   /gene="moeW"
FT                   /locus_tag="Mb2366c"
FT                   /product="POSSIBLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEW"
FT                   /note="Mb2366c, moeW, len: 318 aa. Equivalent to Rv2338c,
FT                   len: 318 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 318 aa overlap). Possible moeW,
FT                   molybdoptenum biosynthesis protein, showing some similarity
FT                   to several molybdopterin biosynthesis proteins e.g.
FT                   O27613|MTH1571 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEB
FT                   HOMOLOG from Methanobacterium thermoautotrophicum (251 aa),
FT                   FASTA scores: opt: 309, E(): 4.7e-14; (30.7% identity in
FT                   254 aa overlap); Q9KPQ5|VC2311 HESA/MOEB/THIF FAMILY
FT                   PROTEIN from Vibrio cholerae (273 aa), FASTA scores: opt:
FT                   255, E(): 4e-09, (36.25% identity in 149 aa overlap);
FT                   Q9PD34|XF1545 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN from
FT                   Xylella fastidiosa (276 aa), FASTA scores: opt: 233,E():
FT                   1e-07, (33.6% identity in 128 aa overlap); etc. SEEMS TO
FT                   BELONG TO THE HESA/MOEB/THIF FAMILY."
FT                   /db_xref="GOA:Q7TYS7"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS7"
FT                   /protein_id="CAD97227.1"
FT                   /translation="MRAGADAPDSGRVKESAPWSYDEAFCRNLGLISPTEQQRLRNSRV
FT                   AIAGMGGVGGIDMVALARMGIGKFTIADPDVFEIRNSNRQYGAMRSTNGQAKAEVMRNI
FT                   VHDINPEAEIRAFCEPIGKENAATFLEGADVLVDGIDAFEIDLRRLLYREAQQRGIYAL
FT                   GAGPLGFSTAWVVFDPKGMTFDRYFDLSDAMNTVDKFVAFIAGIAPSATHRRSIDLSYV
FT                   DIENRTGPSVGLACHLASGVVAAEVLKILLGHGRVYAAPYFHQFDAYRSIYVRKRLRCG
FT                   NRHPLQRVKRRLLARYINRRSAGVIPGLRYHRTEPSY"
FT   CDS             81290..83770
FT                   /transl_table=11
FT                   /gene="mmpL9a"
FT                   /locus_tag="Mb2367"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT
FT                   PROTEIN MMPL9A [FIRST PART]"
FT                   /note="Mb2367, mmpL9a, len: 826 aa. Equivalent to 5' end of
FT                   Rv2339, len: 962 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (99.9% identity in 826 aa overlap). Probable mmpL9,
FT                   conserved transmembrane transport protein (see citation
FT                   below), with strong similarity to other Mycobacterial
FT                   proteins e.g. P54881|YV34_MYCLE|MML4_MYCLE hypothetical
FT                   105.2 kd protein from Mycobacterium leprae (959 aa), FASTA
FT                   scores: opt: 3799, E(): 0, (59.3% identity in 937 aa
FT                   overlap); G699237|U1740AB from Mycobacterium leprae; and
FT                   MTCY20G9.34; MTCY48.08c; MTCY19G5.06 from M. tuberculosis.
FT                   BELONGS TO THE MMPL FAMILY. REMARK-M.bovis-M.tuberculosis:
FT                   In Mycobacterium tuberculosis strain H37Rv, mmpL9 exists as
FT                   a single gene. In Mycobacterium bovis, truncation due to a
FT                   single base transition (g-a) splits mmpL9 into 2 parts,
FT                   mmpL9a and mmpL9b, resulting in a shorter mmpL9a product."
FT                   /db_xref="GOA:Q7TYS6"
FT                   /db_xref="InterPro:IPR004869"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS6"
FT                   /protein_id="CAD97228.1"
FT                   /translation="MVPGEVHMSDTPSGPHPIIPRTIRLAAIPILLCWLGFTVFVSVVV
FT                   PPLEAIGETRAVAVAPDDAQSMRAMRRAGKVFNEFDSNSIAMVVLESDQPLGEKAHRYY
FT                   DHLVDTLVLDQSHIQHIQDFWRDPLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEA
FT                   VRKIVANSTPPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYRSIA
FT                   TTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAGTDYAIFLVGRYQ
FT                   EARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCLSFARLTLFHTMGPPLAIGMLV
FT                   SVAAALTLAPAIIAIAGRFGLLDPKRRLKTRGWRRVGTAVVRWPGPILATSVALALVGL
FT                   LALPGYRPGYNDRYYLRAGTPVNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLV
FT                   IDKIAKEVLHVSGVERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADML
FT                   TMSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADIDDFVRPLR
FT                   SYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDMNKMEALTPQFLALLPPM
FT                   ITTMKTMRTMMLTMRSTISGVQDQMADMQDHATAMGQAFDTAKSGDSFYLPPEAFDNAE
FT                   FQQGMKLFLSPNGKAVRFVISHESDPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIG
FT                   GTAATYQDIRDGTKYDILIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGL
FT                   SVLIWQHFVGLQVH"
FT   CDS             83783..84178
FT                   /transl_table=11
FT                   /gene="mmpL9b"
FT                   /locus_tag="Mb2368"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT
FT                   PROTEIN MMPL9B [SECOND PART]"
FT                   /note="Mb2368, mmpL9b, len: 131 aa. Equivalent to 3' end of
FT                   Rv2339, len: 962 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (100.0% identity in 131 aa overlap). Probable mmpL9,
FT                   conserved transmembrane transport protein (see citation
FT                   below), with strong similarity to other Mycobacterial
FT                   proteins e.g. P54881|YV34_MYCLE|MML4_MYCLE hypothetical
FT                   105.2 kd protein from Mycobacterium leprae (959 aa), FASTA
FT                   scores: opt: 3799, E(): 0, (59.3% identity in 937 aa
FT                   overlap); G699237|U1740AB from Mycobacterium leprae; and
FT                   MTCY20G9.34; MTCY48.08c; MTCY19G5.06 from M. tuberculosis.
FT                   BELONGS TO THE MMPL FAMILY. REMARK-M.bovis-M.tuberculosis:
FT                   In Mycobacterium tuberculosis strain H37Rv, mmpL9 exists as
FT                   a single gene. In Mycobacterium bovis, truncation due to a
FT                   single base transition (g-a) splits mmpL9 into 2 parts,
FT                   mmpL9a and mmpL9b."
FT                   /db_xref="GOA:Q7TYS5"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS5"
FT                   /protein_id="CAD97229.1"
FT                   /translation="MSVIVLLAVGSDYNLLLVSRFKEEVGAGLKTGIIRAMAGTGAVVT
FT                   SAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPN
FT                   MIHSRPTVPEAHTRQGARRIQPHLHRG"
FT   CDS             complement(84264..85505)
FT                   /transl_table=11
FT                   /gene="PE_PGRS39"
FT                   /locus_tag="Mb2369c"
FT                   /product="PE-PGRS FAMILY PROTEIN"
FT                   /note="Mb2369c, PE_PGRS39, len: 413 aa. Equivalent to
FT                   Rv2340c, len: 413 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (100.0% identity in 413 aa overlap). Member
FT                   of the Mycobacterium tuberculosis PE_family, PGRS subfamily
FT                   of gly-rich proteins, similar to others eg
FT                   YI18_MYCTU|Q50615|Rv1818c|MTCY1A11.25 PE-PGRS FAMILY
FT                   PROTEIN from Mycobacterium tuberculosis (498 aa), FASTA
FT                   scores: opt: 710, E(): 1.4e-22, (41.0% identity in 368 aa
FT                   overlap); O53884|Rv0872v|MTV043.65c PGRS-FAMILY PROTEIN
FT                   from Mycobacterium tuberculosis (606 aa), FASTA scores:
FT                   opt: 708, E(): 1.9e-22, (42.4% identity in 389 aa overlap);
FT                   etc."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS4"
FT                   /protein_id="CAD97230.1"
FT                   /translation="MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGD
FT                   DVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGV
FT                   VSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGN
FT                   PGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGR
FT                   DIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAI
FT                   GGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPG
FT                   NSARRADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRD
FT                   QLLRALGLRPPGHE"
FT   tRNA            complement(86004..86076)
FT                   /gene="asnT"
FT                   /locus_tag="asnT"
FT                   /note="asnT, len: 73 nt. Equivalent to asnT, len: 73 nt,
FT                   from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 73 nt overlap). tRNA-Asn, anticodon gtt."
FT   CDS             86194..86613
FT                   /transl_table=11
FT                   /gene="lppQ"
FT                   /locus_tag="Mb2370"
FT                   /product="PROBABLE CONSERVED LIPOPROTEIN LPPQ"
FT                   /note="Mb2370, lppQ, len: 139 aa. Equivalent to Rv2341,
FT                   len: 139 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 139 aa overlap). Probable lppQ,
FT                   conserved lipoprotein, showing some similarity with
FT                   Rv1228|O33224|LPQX|MTCI61.11 from Mycobacterium
FT                   tuberculosis (185 aa), FASTA scores: opt: 155; E(): 0.0073;
FT                   (31.9% identity in 116 aa overlap). Also shows few
FT                   similarity with P29228|VLPA_MYCHR variant surface antigen A
FT                   precursor from Mycoplasma hyorhinis (157 aa), FASTA scores:
FT                   opt: 96, E(): 7.3, (23.1% identity in 143 aa overlap).
FT                   Contains PS00013 Prokaryotic membrane lipoprotein lipid
FT                   attachment site."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS3"
FT                   /protein_id="CAD97231.1"
FT                   /translation="MPVGGRQHVFEKLASILGLVAAPLMLLGLSACGRSAGKTSEPTCP
FT                   TEPIDAADSSTTPDPSCVVRATEINGNGSRIQTWTGSYDAAATQSGGVCGGTCNFHATV
FT                   RFTVDEGQISGSVDQVYQAAMVAIATRPTSPSLAP"
FT   CDS             86869..87126
FT                   /transl_table=11
FT                   /gene="Mb2371"
FT                   /locus_tag="Mb2371"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2371, -, len: 85 aa. Equivalent to Rv2342, len: 85
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 85 aa overlap). Conserved hypothetical protein,
FT                   highly similar to Q9CCG1|ML0834 HYPOTHETICAL PROTEIN from
FT                   Mycobacterium leprae (100 aa), FASTA scores: opt: 392, E():
FT                   2.9e-20, (78.2% identity in 78 aa overlap). N-terminus
FT                   highly similar to N-terminal part of Q9L085|SCC24.32
FT                   PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (108
FT                   aa), FASTA scores: opt: 122, E(): 0.077, (39.15% identity
FT                   in 46 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS2"
FT                   /protein_id="CAD97232.1"
FT                   /translation="MIGYVAVLGLGYVLGAKAGRRRYEQIASTYRALTGSPVARSMIEG
FT                   GRRKIANRISPDAGFVTLAEIDNQTAVVQRGVERQPKTAR"
FT   CDS             complement(87130..89049)
FT                   /transl_table=11
FT                   /gene="dnaG"
FT                   /locus_tag="Mb2372c"
FT                   /product="PROBABLE DNA PRIMASE DNAG"
FT                   /EC_number="2.7.7.-"
FT                   /note="Mb2372c, dnaG, len: 639 aa. Equivalent to Rv2343c,
FT                   len: 639 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 639 aa overlap). Probable dnaG, DNA
FT                   primase (EC 2.7.7.-), equivalent to O52200|PRIM_MYCSM|DNAG
FT                   DNA PRIMASE from Mycobacterium smegmatis (636 aa), FASTA
FT                   scores: opt: 3504, E(): 5.5e-202, (81.55% identity in 639
FT                   aa overlap); and Q9CCG2|DNAG|ML0833 DNA PRIMASE from
FT                   Mycobacterium leprae (642 aa), FASTA scores: opt: 3443,
FT                   E(): 2.5e-198, (80.4% identity in 642 aa overlap). Also
FT                   highly similar to many DNA primases e.g.
FT                   Q9S1N4|PRIM_STRCO|DNAG|SC7A8.07c from Streptomyces
FT                   coelicolor (641 aa), FASTA scores: opt: 1899, E():
FT                   5.1e-106, (47.9% identity in 643 aa overlap);
FT                   P74893|PRIM_SYNP7|DNAG from Synechococcus sp. strain PCC
FT                   7942 (Anacystis nidulans R2) (616 aa), FASTA scores: opt:
FT                   860, E(): 6.6e-44, (35.3% identity in 513 aa overlap);
FT                   P05096|PRIM_BACSU from Bacillus subtilis (603 aa) FASTA
FT                   scores: opt: 800, E(): 2.5e-40, (33.7% identity in 430 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:P63963"
FT                   /db_xref="HSSP:1D0Q"
FT                   /db_xref="InterPro:IPR002694"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63963"
FT                   /protein_id="CAD97233.1"
FT                   /translation="MSGRISDRDIAAIREGARIEDVVGDYVQLRRAGADSLKGLCPFHN
FT                   EKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGHTISYTGAA
FT                   TSVQRDRGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAAAARKFGCGFAP
FT                   SGWDSLTKHLQRKGFEFEELEAAGLSRQGRHGPMDRFHRRLLWPIRTSAGEVVGFGARR
FT                   LFDDDAMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGV
FT                   TTAVASCGTAFGGEHLAMLRRLMMDDSFFRGELIYVFDGDEAGRAAALKAFDGEQKLAG
FT                   QSFVAVAPDGMDPCDLRLKCGDAALRDLVARRTPLFEFAIRAAIAEMDLDSAEGRVAAL
FT                   RRCVPMVGQIKDPTLRDEYARQLAGWVGWADVAQVIGRVRGEAKRTKHPRLGRLGSTTI
FT                   ARAAQRPTAGPPTELAVRPDPRDPTLWPQREALKSALQYPALAGPVFDALTVEGFTHPE
FT                   YAAVRAAIDTAGGTSAGLSGAQWLDMVRQQTTSTVTSALISELGVEAIQVDDDKLPRYI
FT                   AGVLARLQEVWLGRQIAEVKSKLQRMSPIEQGDEYHALFGDLVAMEAYRRSLLEQASGD
FT                   DLTA"
FT   CDS             complement(89054..90349)
FT                   /transl_table=11
FT                   /gene="dgt"
FT                   /locus_tag="Mb2373c"
FT                   /product="PROBABLE DEOXYGUANOSINE TRIPHOSPHATE
FT                   TRIPHOSPHOHYDROLASE DGT (DGTPASE) (DGTP
FT                   TRIPHOSPHOHYDROLASE)"
FT                   /EC_number="3.1.5.1"
FT                   /note="Mb2373c, dgt, len: 431 aa. Equivalent to Rv2344c,
FT                   len: 431 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 431 aa overlap). Probable dgt,
FT                   deoxyguanosine triphosphate triphosphohydrolase (EC
FT                   3.1.5.1), equivalent to Q9CCG3|DGT|ML0831 PUTATIVE
FT                   DEOXYGUANOSINE TRIPHOSPHATE TRIPHOSPHOHYDROLASE from
FT                   Mycobacterium leprae (429 aa), FASTA scores: opt: 2316,
FT                   E(): 1.6e-137, (83.85% identity in 421 aa overlap); and
FT                   O52199|DGTP_MYCSM|AF027507_2 DEOXYGUANOSINETRIPHOSPHATE
FT                   TRIPHOSPHOHYDROLASE from Mycobacterium smegmatis (428 aa),
FT                   FASTA scores: opt: 1991, E(): 3.4e-117, (73.5% identity in
FT                   422 aa overlap). Also highly similar or similar to several
FT                   deoxyguanosine triphosphate hydrolases e.g.
FT                   Q9L2E9|SC7A8.09c PUTATIVE DEOXYGUANOSINETRIPHOSPHATE
FT                   TRIPHOSPHOHYDROLASE from Streptomyces coelicolor (424 aa),
FT                   FASTA scores: opt: 1216, E(): 1e-68, (51.05% identity in
FT                   425 aa overlap); BAB48544|MLL1093 DGTP TRIPHOSPHOHYDROLASE
FT                   from Rhizobium loti (Mesorhizobium loti) (404 aa), FASTA
FT                   scores: opt: 489, E(): 3.1e-23, (33.85% identity in 387 aa
FT                   overlap); P15723|DGTP_ECOLI|DGT|B0160 from Escherichia coli
FT                   strain K12 (504 aa), FASTA scores: opt: 173, E(): 0.0022,
FT                   (31.65% identity in 259 aa overlap); etc. BELONGS TO THE
FT                   DGTPASE FAMILY."
FT                   /db_xref="GOA:P0A541"
FT                   /db_xref="InterPro:IPR006674"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A541"
FT                   /protein_id="CAD97234.1"
FT                   /translation="MSASEHDPYDDFDRQRRVAEAPKTAGLPGTEGQYRSDFARDRARV
FT                   LHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELAGLAH
FT                   DIGHPPYGHNGERALDEVAASHGGFEGNAQNFRILTSLEPKVVDAQGLSAGLNLTRASL
FT                   DAVTKYPWMRGDGLGSQRRKFGFYDDDRESAVWVRQGAPPERACLEAQVMDWADDVAYS
FT                   VHDVEDGVVSERIDLRVLAAEEDAAALARLGEREFSRVSADELMAAARRLSRLPVVAAV
FT                   GKYDATLSASVALKRLTSELVGRFASAAIATTRAAAGPGPLVRFRADLQVPDLVRAEVA
FT                   VLKILALQFIMSDPRHLETQARQRERIHRVAHRLYSGAPQTLDPVYAAAFNTAADDAAR
FT                   LRVVVDQIASYTEGRLERIDADQLGVSRNALD"
FT   CDS             90418..92400
FT                   /transl_table=11
FT                   /gene="Mb2374"
FT                   /locus_tag="Mb2374"
FT                   /product="POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2374, -, len: 660 aa. Equivalent to Rv2345, len:
FT                   660 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 660 aa overlap). Possible conserved
FT                   transmembrane protein, with hydrophobic stretch at
FT                   N-terminal end around position 180. Similar to O52198
FT                   HYPOTHETICAL 21.2 KDA PROTEIN (FRAGMENT) from Mycobacterium
FT                   smegmatis (195 aa), FASTA scores: opt: 589, E(): 1.5e-23;
FT                   (47.2% identity in 195 aa overlap)."
FT                   /db_xref="GOA:Q7TYS1"
FT                   /db_xref="InterPro:IPR007621"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS1"
FT                   /protein_id="CAD97235.1"
FT                   /translation="MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTS
FT                   SGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSALNWAQRTTRTSELGNYDALLAVATT
FT                   GREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSSRVV
FT                   LLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRS
FT                   MVVDVDNAVRTSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPET
FT                   PAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTRIGP
FT                   TQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDA
FT                   VRAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTG
FT                   RTGDLIAARDAAARALDRARGAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRS
FT                   LEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYA
FT                   NAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIP
FT                   TSFGGSSNAPGSSPDGGFLGGGGRF"
FT   CDS             complement(92485..92667)
FT                   /transl_table=11
FT                   /gene="esxO"
FT                   /locus_tag="Mb2375c"
FT                   /standard_name="ES6_6; Mtb9.9E"
FT                   /product="PUTATIVE ESAT-6 LIKE PROTEIN 6"
FT                   /note="Mb2375c, esxO, len: 60 aa. Equivalent to 3' end of
FT                   Rv2346c, len: 94 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (98.3% identity in 60 aa overlap). esxO, putative
FT                   ESAT-6 like protein 6, conserved hypotheticalprotein,
FT                   member of proteins family from Mycobacterium tuberculosis,
FT                   with O53942|Rv1793|MTV049.15, O05300|Rv1198|MTCI364.10,
FT                   MTCY15C10.33, P96364|MTCY07H7B.03|Rv1037c|MTCY10G2.12,
FT                   MTCI364.10, etc. BELONGS TO THE ESAT6 FAMILY.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
FT                   large 8963 bp deletion (RD5) leads to the loss of the NH2
FT                   part of Mb2375c, and the 9 following CDSs up to Rv2356
FT                   including the 3 phospolipases C enzymes plcC, plcB and
FT                   plcA, compared to the homolog in Mycobacterium tuberculosis
FT                   H37Rv."
FT                   /db_xref="InterPro:IPR009416"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYS0"
FT                   /protein_id="CAD97236.1"
FT                   /translation="MLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAG
FT                   NNMAQTDSAVGSSWA"
FT   CDS             complement(92651..94024)
FT                   /transl_table=11
FT                   /gene="PPE71"
FT                   /locus_tag="Mb2376c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb2376c, PPE71, len: 457 aa. Equivalent to 5' end of
FT                   MT2423, len: 621 aa, from Mycobacterium tuberculosis strain
FT                   CDC1551, (98.475% identity in 459 aa overlap). PPE FAMILY
FT                   PROTEIN. REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   bovis, there is a large 8963 bp deletion (RD5) in between
FT                   Mb2375c and Mb2377c compared to Mycobacterium tuberculosis
FT                   strain H37Rv. In this region of Mycobacterium bovis two
FT                   substitutions are present that encode a CDS, Mb2376c,
FT                   equivalent to that found in Mycobacterium tuberculosis
FT                   strain CDC1551. The first substitution is of 1218 bp to 350
FT                   bp and the second is of 123 bp to 431 bp."
FT                   /db_xref="InterPro:IPR002989"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR9"
FT                   /protein_id="CAD97237.1"
FT                   /translation="MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAES
FT                   FGLVTSGLAGGSGQAWQGAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAAR
FT                   AAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASA
FT                   AAALAPWQQAVPGLLGLLDSAQSSAQAVTAQAVGSTVPGPLQGINFGFGNIGSLNLGSG
FT                   NTGDTNVGSGNIGNTNLGGGNIGSFNLGSGNQGDINLGIGNVGNLNLGSGNFGSQNLGS
FT                   GNIGSTNVGSGNIGSTNVGSGNIGDTNFGNGNNGNFNFGSGNTGSNNIGFGNTGSGNFG
FT                   FGNTGNNNIGIGLTGDGQIGIGGLNSGSGNIGFGNSGTGNVGLFNSGTGNVGFGNSGTA
FT                   NTGFGNAGNVNTGFWNGGSTNTGLANAGAGNTGFFDAGNYNFGSLNAGNINSSFVGRG"
FT   CDS             complement(94762..96606)
FT                   /transl_table=11
FT                   /gene="PPE40"
FT                   /locus_tag="Mb2377c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb2377c, PPE40, len: 614 aa. Equivalent to Rv2356c,
FT                   len: 615 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 615 aa overlap). Member of Mycobacterium
FT                   tuberculosis PPE_family, highly similar to others e.g.
FT                   Q10778|MTCY48.17|YF48_MYCTU HYPOTHETICAL PPE-FAMILY PROTEIN
FT                   (678 aa), FASTA scores: opt: 1888, E(): 1.9e-78, (54.4%
FT                   identity in 667 aa overlap); Q10540|MTCY31.06c,
FT                   E241779|MTCY98, P42611|MTV037.06c, Q10813|MTCY274.23c,
FT                   P71657|MTCY02B10.25c, MTCY03C7.23, P71869|MTCY03C7.24c,
FT                   etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,
FT                   a 3 bp deletion (gcg-*) leads to a slightly shorter product
FT                   compared to its homolog in Mycobacterium tuberculosis
FT                   strain H37Rv (614 aa versus 615 aa)."
FT                   /db_xref="InterPro:IPR000030"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR8"
FT                   /protein_id="CAD97238.1"
FT                   /translation="MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAES
FT                   FGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAA
FT                   RAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGAS
FT                   AAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNI
FT                   GGTNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGN
FT                   IGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFG
FT                   NTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNT
FT                   GFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGN
FT                   TGFFNAGDSNTGFANAGNVNTGFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNL
FT                   GTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSG
FT                   NNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR"
FT   CDS             complement(96744..98135)
FT                   /transl_table=11
FT                   /gene="glyS"
FT                   /locus_tag="Mb2378c"
FT                   /product="PROBABLE GLYCYL-tRNA SYNTHETASE GLYS
FT                   (GLYCINE--tRNA LIGASE) (GLYRS)"
FT                   /EC_number="6.1.1.14"
FT                   /note="Mb2378c, glyS, len: 463 aa. Equivalent to Rv2357c,
FT                   len: 463 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 463 aa overlap). Probable glyS,
FT                   glycyl-tRNA synthetase (EC 6.1.1.14), equivalent to
FT                   Q9CCG4|GLYS|ML0826 PUTATIVE GLYCYL-TRNA SYNTHASE from
FT                   Mycobacterium leprae (463 aa), FASTA scores: opt: 2898,
FT                   E(): 1e-179, (90.2% identity in 459 aa overlap). Also
FT                   highly similar to others e.g. Q9L2H9|SYG_STRCO|SCC121.07c
FT                   from Streptomyces coelicolor (460 aa), FASTA scores: opt:
FT                   2210, E(): 2.9e-135, (68.3% identity in 457 aa overlap);
FT                   Q9PPZ7|SYG_UREPA|GLYS|UU493 GLYCYL-TRNA SYNTHETASE from
FT                   Ureaplasma parvum (Ureaplasma urealyticum biotype 1) (473
FT                   aa), FASTA scores: opt: 1254, E(): 1.7e-73, (45.25%
FT                   identity in 462 aa overlap);
FT                   P75425|SYG_MYCPN|GLYS|MPN354|MP482 GLYCYL-TRNA SYNTHETASE
FT                   from Mycoplasma pneumoniae (449 aa), FASTA scores: opt:
FT                   1074, E(): 6.9e-62, (39.45% identity in 454 aa overlap);
FT                   etc. Contains PS00017 ATP/GTP-binding site motif A
FT                   (P-loop), and PS00179 Aminoacyl-transfer RNA synthetases
FT                   class-II signature 1. BELONGS TO CLASS-II AMINOACYL-TRNA
FT                   SYNTHETASE FAMILY."
FT                   /db_xref="GOA:P67033"
FT                   /db_xref="HSSP:1ATI"
FT                   /db_xref="InterPro:IPR018160"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67033"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97239.1"
FT                   /translation="MHHPVAPVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVEL
FT                   KENIKRQWWRSVVTGRDDVVGIDSSIILPREVWVASGHVDVFHDPLVESLITHKRYRAD
FT                   HLIEAYEAKHGHPPPNGLADIRDPETGEPGQWTQPREFNMMLKTYLGPIETEEGLHYLR
FT                   PETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVE
FT                   PATAKEWHQYWIDNRLQWYIDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGNP
FT                   WGELEGVANRTDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDA
FT                   YTEDEAPNTKGGMDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAELRKCWNID
FT                   FDDAGAIGRRYRRQDEVGTPFCVTVDFDSLQDNAVTVRERDAMTQDRVAMSSVADYLAV
FT                   RLKGS"
FT   CDS             98317..98724
FT                   /transl_table=11
FT                   /gene="Mb2379"
FT                   /locus_tag="Mb2379"
FT                   /product="PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
FT                   (PROBABLY ARSR-FAMILY)"
FT                   /note="Mb2379, -, len: 135 aa. Equivalent to Rv2358, len:
FT                   135 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 135 aa overlap). Probable
FT                   transcriptional regulator, arsR family, equivalent to
FT                   Q9CCG5|ML0825 PUTATIVE ARSR-FAMILY TRANSCRIPTIONAL
FT                   REGULATOR from Mycobacterium leprae (140 aa), FASTA scores:
FT                   opt: 647, E(): 2e-34, (72.9% identity in 140 aa overlap).
FT                   Also similar to others e.g. BAB48273|MLR0745
FT                   Transcriptional regulator from Rhizobium loti
FT                   (Mesorhizobium loti) (104 aa), FASTA scores: opt: 185, E():
FT                   3.4e-05, (43.25% identity in 74 aa overlap) (has its
FT                   N-terminus shorter); P15905|ARR1_ECOLI arsenical resistance
FT                   operon repressor from Escherichia coli (117 aa), FASTA
FT                   scores: opt: 164, E(): 8.1e-05, (39.1% identity in 69 aa
FT                   overlap); etc. Also similar to O53838|Rv0827|MTV043.19c
FT                   PUTATIVE TRANSCRIPTIONAL REGULATOR from Mycobacterium
FT                   tuberculosis (130 aa), FASTA scores: opt: 201, E(): 4e-06,
FT                   (35.7% identity in 98 aa overlap); and
FT                   O69711|Rv3744|MTV025.092 PUTATIVE REGULATORY PROTEIN from
FT                   Mycobacterium tuberculosis (120 aa), FASTA scores: opt:
FT                   209, E(): 1.2e-06, (35.5 % identity in 93 aa overlap).
FT                   Contains possible helix-turn-helix motif at aa 72-93 (Score
FT                   1103, +2.94 SD). Belongs to the ARSR family of
FT                   transciptional regulators."
FT                   /db_xref="GOA:Q7TYR7"
FT                   /db_xref="InterPro:IPR001845"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR7"
FT                   /protein_id="CAD97240.1"
FT                   /translation="MVTSPSTPTAAHEDVGADEVGGHQHPADRFAECPTFPAPPPREIL
FT                   DAAGELLRALAAPVRIAIVLQLRESQRCVHELVDALHVPQPLVSQHLKILKAAGVVTGE
FT                   RSGREVLYRLADHHLAHIVLDAVAHAGEDAI"
FT   CDS             98721..99113
FT                   /transl_table=11
FT                   /gene="furB"
FT                   /locus_tag="Mb2380"
FT                   /product="PROBABLE FERRIC UPTAKE REGULATION PROTEIN FURB"
FT                   /note="Mb2380, furB, len: 130 aa. Equivalent to Rv2359,
FT                   len: 130 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.2% identity in 130 aa overlap). Probable furB, ferric
FT                   uptake regulation protein, equivalent to FURB|ML0824|Q9CCG6
FT                   PUTATIVE FERRIC UPTAKE REGULATORY PROTEIN from
FT                   Mycobacterium leprae (131 aa), FASTA scores: opt: 765, E():
FT                   1.7e-43, (86.9% identity in 130 aa overlap). Also highly
FT                   similar to FERRIC UPTAKE REGULATION PROTEINS e.g.
FT                   Q9L2H5|SCC121.11 PUTATIVE METAL UPTAKE REGULATION PROTEIN
FT                   from Streptomyces coelicolor (139 aa), FASTA scores: opt:
FT                   547, E(): 3.4e-29, (59.4% identity in 133 aa overlap);
FT                   P06975|FUR_ECOLI from Escherichia coli (148 aa), FASTA
FT                   scores: opt: 322, E(): 1.9e-14, (37.9% identity in 132 aa
FT                   overlap); P45599|FUR_KLEPN FERRIC UPTAKE REGULATION PROTEIN
FT                   from Klebsiella pneumoniae (155 aa), FASTA scores: opt:
FT                   314, E(): 6.7e-14, (36.35% identity in 132 aa overlap);
FT                   etc. BELONGS TO THE FUR FAMILY."
FT                   /db_xref="GOA:Q7TYR6"
FT                   /db_xref="HSSP:1MZB"
FT                   /db_xref="InterPro:IPR002481"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR6"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97241.1"
FT                   /translation="MSAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLT
FT                   TVYRTLQSMASSGLVDTLRTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVEAWAA
FT                   EVATKHGFSDVSHTIEIFGTCSDCRS"
FT   CDS             complement(99221..99649)
FT                   /transl_table=11
FT                   /gene="Mb2381c"
FT                   /locus_tag="Mb2381c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2381c, -, len: 142 aa. Equivalent to Rv2360c, len:
FT                   142 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.3% identity in 142 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR5"
FT                   /protein_id="CAD97242.1"
FT                   /translation="MPSLPDRLASILRDVLPAEEEPDGALTVRHDGTFASLRVVSIAED
FT                   LELVSLTQILAWDLPLTKRLTEQVAKQARDINFGSVSLREKVSEKAARRSSGRPASNTA
FT                   DVMLRYNFPGTGLTDDALRTLILLVLETGATIRSALVG"
FT   CDS             complement(99649..100539)
FT                   /transl_table=11
FT                   /gene="Mb2382c"
FT                   /locus_tag="Mb2382c"
FT                   /product="LONG (C50) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE
FT                   (Z-DECAPRENYL DIPHOSPHATE SYNTHASE)"
FT                   /EC_number="2.5.1.-"
FT                   /note="Mb2382c, -, len: 296 aa. Equivalent to Rv2361c, len:
FT                   296 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 296 aa overlap). Long (C50) chain
FT                   Z-isoprenyl diphosphate synthase (EC 2.5.1.-) (see citation
FT                   below), equivalent to UPPS_MYCLE|ML0634|B1937_F2_65|P38119
FT                   UNDECAPRENYL PYROPHOSPHATE SYNTHETASE from Mycobacterium
FT                   leprae (296 aa), FASTA scores: opt: 1789, E(): 1.8e-97,
FT                   (86.5% identity in 296 aa overlap). Also highly similar to
FT                   others e.g. UPPS|Q9L2H4 UNDECAPRENYL PYROPHOSPHATE
FT                   SYNTHETASE from Streptomyces coelicolor (277 aa), FASTA
FT                   scores: opt: 1098, E(): 8.2e-60, (63.5% identity in 247 aa
FT                   overlap); Q55482|UPPS_SYNY3|SLL0506 from Synechocystis sp.
FT                   strain PCC 6803 (249 aa), FASTA scores: opt: 686, E():
FT                   4.2e-33, (46.4% identity in 235 aa overlap);
FT                   O67291|UPPS_AQUAE|AQ_1248 from Aquifex aeolicus (231 aa),
FT                   FASTA scores: opt: 684, E(): 5.2e-33, (46.3% identity in
FT                   229 aa overlap); etc. Also similar to Rv1086|MTV017.39 from
FT                   Mycobacterium tuberculosis. Contains PS01066 Hypothetical
FT                   YBR002c family signature. SEEMS TO BELONG TO THE UPP
FT                   SYNTHETASE FAMILY. Note that previously known as uppS."
FT                   /db_xref="GOA:P60478"
FT                   /db_xref="InterPro:IPR018520"
FT                   /db_xref="UniProtKB/Swiss-Prot:P60478"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97243.1"
FT                   /translation="MARDARKRTSSNFPQLPPAPDDYPTFPDTSTWPVVFPELPAAPYG
FT                   GPCRPPQHTSKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIA
FT                   CGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVRRRRDTLKKLGVRIRWVGSR
FT                   PRLWRSVINELAVAEEMTKSNDVITINYCVNYGGRTEITEATREIAREVAAGRLNPERI
FT                   TESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWA
FT                   ACEEYASRTRRFGSA"
FT   CDS             complement(100532..101329)
FT                   /transl_table=11
FT                   /gene="Mb2383c"
FT                   /locus_tag="Mb2383c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2383c, -, len: 265 aa. Equivalent to Rv2362c, len:
FT                   265 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 265 aa overlap). Conserved hypothetical
FT                   protein, equivalent to the Mycobacterium leprae proteins
FT                   Q49754|B1937_F1_25 Hypothetical protein (269 aa), FASTA
FT                   scores: opt: 1561, E(): 8.5e-93, (86.6% identity in 268 aa
FT                   overlap); and Q9CCN0|ML0633 Hypothetical protein (268 aa),
FT                   FASTA scores: opt: 1560, E(): 8.5e-93, (86.6% identity in
FT                   268 aa overlap). Also highly similar to Q9L2H3|SCC121.13c
FT                   HYPOTHETICAL 27.1 KDA PROTEIN from Streptomyces coelicolor
FT                   (251 aa), FASTA scores: opt: 843, E(): 6.9e-47, (52.2%
FT                   identity in 249 aa overlap); ans similar to other
FT                   hypothetical proteins. Weak similarity with
FT                   P42095|RECO_BACSU DNA REPAIR PROTEIN RECOMBINASE from
FT                   Bacillus subtilis (255 aa), FASTA scores: opt: 270, E():
FT                   3.6e-10, (26.4% identity in 182 aa overlap)."
FT                   /db_xref="GOA:P65984"
FT                   /db_xref="InterPro:IPR003717"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65984"
FT                   /protein_id="CAD97244.1"
FT                   /translation="MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRS
FT                   KFGARLEPFAHIEVQLHPGRNLDIVTQVVSVDAFATDIVADYGRYTCGCAILETAERLA
FT                   GEERAPAPALHRLTVGALRAVADGQRPRDLLLDAYLLRAMGIAGWAPALTECARCATPG
FT                   PHRAFHIATGGSVCAHCRPAGSTTPPLGVVDLMSALYDGDWEAAEAAPQSARSHVSGLV
FT                   AAHLQWHLERQLKTLPLVERFYQADRSVAERRAALIGQDIAGG"
FT   CDS             101391..102845
FT                   /transl_table=11
FT                   /gene="amiA2"
FT                   /locus_tag="Mb2384"
FT                   /product="PROBABLE AMIDASE AMIA2 (AMINOHYDROLASE)"
FT                   /EC_number="3.5.1.4"
FT                   /note="Mb2384, amiA2, len: 484 aa. Equivalent to Rv2363,
FT                   len: 484 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 484 aa overlap). Probable amiA2,
FT                   amidase (EC 3.5.1.4), highly similar or similar to others
FT                   e.g. O28325|YJ54_ARCFU|AF1954 PUTATIVE AMIDASE from
FT                   Archaeoglobus fulgidus (453 aa), FASTA scores: opt: 777,
FT                   E(): 1.1e-38, (35.0% identity in 474 aa overlap);
FT                   Q55424|AMID_SYNY3|SLL0828 PUTATIVE AMIDASE from
FT                   Synechocystis sp. strain PCC 6803 (506 aa), FASTA scores:
FT                   opt: 770, E(): 3e-38, (36.4% identity in 456 aa overlap);
FT                   Q53116|AMDA ENANTIOMERASE-SELECTIVE AMIDASE from
FT                   Rhodococcus sp. (462 aa), FASTA scores: opt: 701, E():
FT                   3.5e-34, (32.7% identity in 468 aa overlap); etc. Also
FT                   highly similar to others from Mycobacterium tuberculosis
FT                   e.g.
FT                   AMI2_MYCTU|AMIB2|Q11056|Rv1263|MT1301|MTCY50.19c|cy50.19c
FT                   AMIDASE (462 aa), FASTA scores: opt: 1141, E(): 2.9e-60,
FT                   (45.4% identity in 454 aa overlap); etc. Contains PS00571
FT                   Amidases signature, and PS00017 ATP/GTP-binding site motif
FT                   A (P-loop). BELONGS TO THE AMIDASE FAMILY."
FT                   /db_xref="GOA:P63491"
FT                   /db_xref="HSSP:1M21"
FT                   /db_xref="InterPro:IPR000120"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63491"
FT                   /protein_id="CAD97245.1"
FT                   /translation="MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSL
FT                   RAIDVSQPTLNAFRVVLTESALADAAAADKRRAAGDTAPLLGIPIAVKDDVDVAGVPTA
FT                   FGTQGYVAPATDDCEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWSRRHT
FT                   PGGSSGGSAAAVAAGLVTAAIGSDGAGSIRIPAAWTHLVGIKPQRGRISTWPLPEAFNG
FT                   VTVNGVLARTVEDAALVLDAASGNVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYT
FT                   GFRAKLHPEILAATQRVGDQLELLGHTVVKGNPDYGLRLSWNFLARSTAGLWEWAERLG
FT                   DEVTLDRRTVSNLRMGHVLSQAILRSARRHEAADQRRVGSIFDIVDVVLAPTTAQPPPM
FT                   ARAFDRLGSFGTDRAIIAACPSTWPWNLLGWPSINVPAGFTSDGLPIGVQLMGPANSEG
FT                   MLISLAAELEAVSGWATKQPQVWWTS"
FT   CDS             complement(102842..103744)
FT                   /transl_table=11
FT                   /gene="era"
FT                   /locus_tag="Mb2385c"
FT                   /product="PROBABLE GTP-BINDING PROTEIN ERA"
FT                   /note="Mb2385c, era, len: 300 aa. Equivalent to Rv2364c,
FT                   len: 300 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 300 aa overlap). Probable era,
FT                   GTP-binding protein, equivalent to
FT                   Q49768|ERA_MYCLE|ML0631|B1937_F3_102 GTP-BINDING PROTEIN
FT                   ERA HOMOLOG from Mycobacterium leprae (300 aa) FASTA
FT                   scores: opt: 1589, E(): 3.4e-88, (81.4% identity in 301 aa
FT                   overlap). Also highly similar to other GTP-binding proteins
FT                   e.g. Q9RDF2|ERA_STRCO|SCC77.06 from Streptomyces coelicolor
FT                   (317 aa), FASTA scores: opt: 1264, E(): 1.1e-68, (64.0%
FT                   identity in 306 aa overlap); Q9KD52|ERA_BACHD|BH1367|BEX
FT                   from Bacillus halodurans (304 aa), FASTA scores: opt: 869,
FT                   (44.8% identity in 297 aa overlap); Q9KIH7|ERA_LACLA|ERAL
FT                   from Lactococcus lactis (subsp. lactis) (Streptococcus
FT                   lactis), and Lactococcus lactis (subsp. cremoris)
FT                   (Streptococcus cremoris) (303 aa), FASTA scores: opt: 781,
FT                   E(): 9.4e-40, (40.25% identity in 298 aa overlap); etc.
FT                   Contains PS00017 ATP/GTP-binding site motif A (P-loop).
FT                   BELONGS TO THE ERA/TRME FAMILY OF GTP-BINDING PROTEINS, ERA
FT                   SUBFAMILY. Note that previously known as bex."
FT                   /db_xref="GOA:P0A563"
FT                   /db_xref="HSSP:1MKY"
FT                   /db_xref="InterPro:IPR005225"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A563"
FT                   /protein_id="CAD97246.1"
FT                   /translation="MTEFHSGFVCLVGRPNTGKSTLTNALVGAKVAITSTRPQTTRHAI
FT                   RGIVHSDDFQIILVDTPGLHRPRTLLGKRLNDLVRETYAAVDVIGLCIPADEAIGPGDR
FT                   WIVEQLRSTGPANTTLVVIVTKIDKVPKEKVVAQLVAVSELVTNAAEIVPVSAMTGDRV
FT                   DLLIDVLAAALPAGPAYYPDGELTDEPEEVLMAELIREAALQGVRDELPHSLAVVIDEV
FT                   SPREGRDDLIDVHAALYVERDSQKGIVIGKGGARLREVGTAARSQIENLLGTKVYLDLR
FT                   VKVAKNWQRDPKQLGRLGF"
FT   CDS             complement(103818..104159)
FT                   /transl_table=11
FT                   /gene="Mb2386c"
FT                   /locus_tag="Mb2386c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2386c, -, len: 113 aa. Equivalent to Rv2365c, len:
FT                   113 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 113 aa overlap). Conserved hypothetical
FT                   protein, highly similar to
FT                   Q49767|ML0630|B1937_F3_101|CAC30138 Hypothetical protein
FT                   from Mycobacterium leprae (108 aa), FASTA scores: opt: 426,
FT                   E(): 1.4e-18, (67.9% identity in 106 aa overlap). Also
FT                   highly similar to Q9RDF3|SCC77.05 from Streptomyces
FT                   coelicolor (132 aa), FASTA scores: opt: 254, E(): 1.9e-18,
FT                   (53.1% identity in 96 aa overlap). Equivalent to AAK46728
FT                   from Mycobacterium tuberculosis strain CDC1551 (93 aa) but
FT                   longer 20 aa."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR4"
FT                   /protein_id="CAD97247.1"
FT                   /translation="MMRRPITLAEQLDAEDAKLVVLARAAMARAEAGAGAAVRDVDGRT
FT                   YAAAPVALSALELTGLQAAVAAAVSSGATGLQAAVLVAGSVDDPGIAAVRELAPTAAII
FT                   VTDRAGNPL"
FT   CDS             complement(104131..105438)
FT                   /transl_table=11
FT                   /gene="Mb2387c"
FT                   /locus_tag="Mb2387c"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2387c, -, len: 435 aa. Equivalent to Rv2366c, len:
FT                   435 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 435 aa overlap). Probable conserved
FT                   transmembrane protein, highly similar to Q9L2L3|SCC117.07
FT                   PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (358
FT                   aa), FASTA scores: opt: 1159, E(): 5.5e-64, (53.0% identity
FT                   in 353 aa overlap); ans similar to hypothetical proteins
FT                   and hemolysin-related proteins e.g. Q9HN02|HLP|VNG2308G
FT                   HEMOLYSIN PROTEIN from Halobacterium sp. strain NRC-1 (457
FT                   aa), FASTA scores: opt: 623, E(): 6.2e-31, (28.4% identity
FT                   in 433 aa overlap); etc. Potential transmembrane protein
FT                   with 2 CBS domains. BELONGS TO THE UPF0053 FAMILY."
FT                   /db_xref="GOA:P67131"
FT                   /db_xref="InterPro:IPR002550"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67131"
FT                   /protein_id="CAD97248.1"
FT                   /translation="MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPG
FT                   AGSLRKVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMVLASF
FT                   VVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNALTPGRGFRNGPFA
FT                   SEIELREVVDLAQQRGVVAADERRMIESVFELGDTPAREVMVPRTEMIWIESDKTAGQA
FT                   MTLAVRSGHSRIPVIGENVDDIVGVVYLKDLVEQTFCSTNGGRETTVARVMRPAVFVPD
FT                   SKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVED
FT                   LGDKRFRVSARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRL
FT                   HAEGGTDHRGRVRIGTVLLSPAEPDGADDEEADHPG"
FT   CDS             complement(105435..105983)
FT                   /transl_table=11
FT                   /gene="Mb2388c"
FT                   /locus_tag="Mb2388c"
FT                   /product="FUNCTION UNKNOWN"
FT                   /note="Mb2388c, -, len: 182 aa. Equivalent to Rv2367c, len:
FT                   182 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 182 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q49752|YN67_MYCLE|ML0628|B1937_F1_21
FT                   HYPOTHETICAL 19.8 KDA PROTEIN from Mycobacterium leprae
FT                   (178 aa), FASTA scores: opt: 1051, E(): 2e-59, (89.1%
FT                   identity in 175 aa overlap). Also highly similar to others
FT                   e.g. Q9L2L4|SCC117.06 CONSERVED HYPOTHETICAL PROTEIN from
FT                   Streptomyces coelicolor (165 aa), FASTA scores: opt: 599,
FT                   E(): 6e-31, (56.5% identity in 154 aa overlap);
FT                   Q9KD56|BH1363 HYPOTHETICAL PROTEIN from Bacillus halodurans
FT                   (159 aa), FASTA scores: opt: 311, E(): 8.3e-13, (45.05%
FT                   identity in 111 aa overlap); etc."
FT                   /db_xref="GOA:P67135"
FT                   /db_xref="InterPro:IPR002036"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67135"
FT                   /protein_id="CAD97249.1"
FT                   /translation="MREHLMSIEVANESGIDVSEAELVSVARFVIAKMDVNPCAELSML
FT                   LLDTAAMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPEFAAE
FT                   QAAAAGHSLGHELALLTIHGVLHLLGYDHAEPDEEKEMFALQDRLLEEWVADQVEAYQH
FT                   DRQDEKDRRLLDKSRYFDL"
FT   CDS             complement(105987..107045)
FT                   /transl_table=11
FT                   /gene="phoH1"
FT                   /locus_tag="Mb2389c"
FT                   /product="PROBABLE PHOH-LIKE PROTEIN PHOH1 (PHOSPHATE
FT                   STARVATION-INDUCIBLE PROTEIN PSIH)"
FT                   /note="Mb2389c, phoH1, len: 352 aa. Equivalent to Rv2368c,
FT                   len: 352 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 352 aa overlap). Probable phoH1,
FT                   phoH-like protein (phosphate starvation-induced protein),
FT                   probably ATP-binding protein, equivalent to
FT                   Q49751|PHOL_MYCLE| ML0627|B1937_F1_20 PHOH-LIKE PROTEIN
FT                   from Mycobacterium leprae (349 aa), FASTA scores: opt:
FT                   1952, E(): 4.7e-107, (88.9% identity in 352 aa overlap).
FT                   Also highly similar to Q9L2L5|SCC117.05 PHOH-LIKE PROTEIN
FT                   from Streptomyces coelicolor (359 aa), FASTA scores: opt:
FT                   1407, E(): 3.6e-75, (63.6% identity in 349 aa overlap);
FT                   Q9RSY1|DR1988 PHOH-RELATED PROTEIN from Deinococcus
FT                   radiodurans (380 aa), FASTA scores: opt: 1053, E():
FT                   1.9e-54, (53.3% identity in 349 aa overlap);
FT                   Q9KD58|PHOH|BH1361 PHOSPHATE STARVATION-INDUCED PROTEIN
FT                   from Bacillus halodurans (320 aa), FASTA scores: opt: 1019,
FT                   E(): 1.6e-52, (54.35% identity in 300 aa overlap);
FT                   P46343|PHOL_BACSU PHOH-LIKE PROTEIN from Bacillus subtilis
FT                   (319 aa), FASTA scores: opt: 1014, E(): 3.2e-52, (50.8%
FT                   identity in 303 aa overlap); etc. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop). BELONGS TO THE PHOH
FT                   FAMILY. Note that previously known as phoH."
FT                   /db_xref="GOA:P0A5S1"
FT                   /db_xref="InterPro:IPR003714"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5S1"
FT                   /protein_id="CAD97250.1"
FT                   /translation="MTSRETRAADAAGARQADAQVRSSIDVPPDLVVGLLGSADENLRA
FT                   LERTLSADLHVRGNAVTLCGEPADVALAERVISELIAIVASGQSLTPEVVRHSVAMLVG
FT                   TGNESPAEVLTLDILSRRGKTIRPKTLNQKRYVDAIDANTIVFGIGPAGTGKTYLAMAK
FT                   AVHALQTKQVTRIILTRPAVEAGERLGFLPGTLSEKIDPYLRPLYDALYDMMDPELIPK
FT                   LMSAGVIEVAPLAYMRGRTLNDAFIVLDEAQNTTAEQMKMFLTRLGFGSKVVVTGDVTQ
FT                   IDLPGGARSGLRAAVDILEDIDDIHIAELTSVDVVRHRLVSEIVDAYARYEEPGSGLNR
FT                   AARRASGARGRR"
FT   CDS             complement(107017..107319)
FT                   /transl_table=11
FT                   /gene="Mb2390c"
FT                   /locus_tag="Mb2390c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2390c, -, len: 100 aa. Equivalent to Rv2369c, len:
FT                   100 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 100 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97251.1"
FT                   /translation="MIVGLADRHGHGRDVAAHRQAQLAGPRVAAVRRHRTGGHRQASSR
FT                   IKVSAHGLGVVRCAPTPSLTGVRMKLQHSSVRQVPVDRPESRHQKPGDVPRDPRC"
FT   CDS             complement(107316..108629)
FT                   /transl_table=11
FT                   /gene="Mb2391c"
FT                   /locus_tag="Mb2391c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2391c, -, len: 437 aa. Equivalent to Rv2370c, len:
FT                   437 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 437 aa overlap). Conserved hypothetical
FT                   protein, member of family proteins from Mycobacterium
FT                   tuberculosis with Rv1453|MTCY493_01c|O06807 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (432
FT                   aa), FASTA scores: opt: 1943, E(): 9.4e-115, (69.9%
FT                   identity in 409 aa overlap); Rv1194c|MTCI364.06c; etc. Also
FT                   similar to AAK45764|MT1500 CONSERVED HYPOTHETICAL PROTEIN
FT                   from Mycobacterium tuberculosis strain CDC1551 (432 aa),
FT                   FASTA scores: opt: 1934, E(): 9.4e-115, (69.9% identity in
FT                   409 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR2"
FT                   /protein_id="CAD97252.1"
FT                   /translation="MVLPKPTPRGRELIRQAAKVALHPTPEWLDELDRATLAAHPSIAA
FT                   DPALATVVSRANRSHLIHFATANLRKPGQPVPANLGPDPLRMARDLVRRGLDASALDVY
FT                   RVGQNVAWQRWTEIAFGLTTDPQELHELLTLPFRSASEFIDATLAGLAAQMQLEYDELT
FT                   RDVHAEHRRIVELILDGAPISRQSAEAKLGYPLDRSHTAAIIWYDDPDDNQNHLDHTAR
FT                   AFGRALGCPQPLIAVASAATRWVWVSDAATLDTDRIHQVLDHAPHARIAVGTTARGIDG
FT                   FRRSHRDALATQRMLARLRSQQRLAFFADIHMIAVLTENPDSAADFITSTLGDLESASP
FT                   QLLTTVLTYINEQCNASRAAHVLHTHRNTLLRRLETAQRLLPRPLDHTIIQVAVAISAL
FT                   QWRGSQTSDPVETPVEGITSPPPESLGRRRSRLAQLER"
FT   CDS             108824..109009
FT                   /transl_table=11
FT                   /gene="PE_PGRS40"
FT                   /locus_tag="Mb2392"
FT                   /product="PE-PGRS FAMILY PROTEIN"
FT                   /note="Mb2392, PE_PGRS40, len: 61 aa. Equivalent to Rv2371,
FT                   len: 61 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 61 aa overlap). Short protein, member
FT                   of the Mycobacterium tuberculosis PE family, PGRS subfamily
FT                   of gly-rich proteins, highly similar to N-terminal part of
FT                   others e.g. AAK44356|MT0132 PE_PGRS FAMILY PROTEIN from
FT                   Mycobacterium tuberculosis strain CDC1551 (561 aa), FASTA
FT                   scores: opt: 217, E( ): 4.9e-08, (69.65% identity in 56 aa
FT                   overlap); etc."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR1"
FT                   /protein_id="CAD97253.1"
FT                   /translation="MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGA
FT                   DEVSADVVALFGWVAR"
FT   CDS             complement(109108..109896)
FT                   /transl_table=11
FT                   /gene="Mb2393c"
FT                   /locus_tag="Mb2393c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2393c, -, len: 262 aa. Equivalent to Rv2372c, len:
FT                   262 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 262 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CCN1|ML0626 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (257 aa), FASTA scores: opt:
FT                   1277, E(): 3e-71, (77.25% identity in 255 aa overlap). Also
FT                   highly similar to others e.g. Q9RDD9|SDRD HYPOTHETICAL 26.1
FT                   KDA PROTEIN from Streptomyces coelicolor (249 aa), FASTA
FT                   scores: opt: 624, E(): 3.2e-31, (45.05% identity in 253 aa
FT                   overlap); P54461|YQEU_BACSU hypothetical 28.8 kd protein
FT                   from Bacillus subtilis (256 aa), FASTA scores: opt: 375,
FT                   E(): 6e-16, (32.5% identity in 234 aa overlap); etc.
FT                   C-terminal half highly similar to Q49763|B1937_F2_57 from
FT                   Mycobacterium leprae (128 aa), FASTA scores: opt: 577, E():
FT                   1.4e-28, (75.8% identity in 124 aa overlap). BELONGS TO THE
FT                   UPF0088 FAMILY."
FT                   /db_xref="GOA:P67203"
FT                   /db_xref="InterPro:IPR006700"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67203"
FT                   /protein_id="CAD97254.1"
FT                   /translation="MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDG
FT                   VGRLARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGAD
FT                   AFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVR
FT                   EEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRL
FT                   GPTVLRTSTAAAVALGAVGVLTSRWDASASDCEYCDVTRR"
FT   CDS             complement(109910..111058)
FT                   /transl_table=11
FT                   /gene="dnaJ2"
FT                   /locus_tag="Mb2394c"
FT                   /product="PROBABLE CHAPERONE PROTEIN DNAJ2"
FT                   /note="Mb2394c, dnaJ2, len: 382 aa. Equivalent to Rv2373c,
FT                   len: 382 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 382 aa overlap). Probable dnaJ2,
FT                   chaperone protein, equivalent to
FT                   Q49762|DNJ2_MYCLE|ML0625|B1937_F2_56 CHAPERONE PROTEIN from
FT                   Mycobacterium leprae (378 aa), FASTA scores: opt: 2301,
FT                   E(): 1.7e-120, (87.5% identity in 382 aa overlap). Also
FT                   highly similar to OTHER CHAPERONE PROTEINS DNAJ/DNAJ2 e.g.
FT                   Q9RDD7|DNJ2_STRCO|SCC77.21c from Streptomyces coelicolor
FT                   (378 aa), FASTA scores: opt: 1456, E(): 1.2e-73, (54.8%
FT                   identity in 385 aa overlap); O52164|DNJ2_STRAL from
FT                   Streptomyces albus (379 aa) FASTA scores: opt: 1378, E():
FT                   2.6e-69, (52.2% identity in 385 aa overlap);
FT                   Q9S5A3|DNAJ_LISMO from Listeria monocytogenes (377 aa),
FT                   FASTA scores: opt: 1013, E(): 4.6e-49, (41.3% identity in
FT                   385 aa overlap); etc. Also similar to Rv0352|MTCY13E10.12
FT                   from Mycobacterium tuberculosis. Contains 1 J domain and 1
FT                   CR domain. BELONGS TO THE DNAJ FAMILY."
FT                   /db_xref="GOA:P63967"
FT                   /db_xref="HSSP:1HDJ"
FT                   /db_xref="InterPro:IPR003095"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63967"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97255.1"
FT                   /translation="MARDYYGLLGVSKNASDADIKRAYRKLARELHPDVNPDEAAQAKF
FT                   KEISVAYEVLSDPDKRRIVDLGGDPLESAAAGGNGFGGFGGLGDVFEAFFGGGFGGGAA
FT                   SRGPIGRVRPGSDSLLRMRLDLEECATGVTKQVTVDTAVLCDRCQGKGTNGDSVPIPCD
FT                   TCGGRGEVQTVQRSLLGQMLTSRPCPTCRGVGVVIPDPCQQCMGDGRIRARREISVKIP
FT                   AGVGDGMRVRLAAQGEVGPGGGPAGDLYVEVHEQAHDVFVREGDHLHCTVSVPMVDAAL
FT                   GVTVTVDAILDGLSEITIPPGTQPGSVITLRGRGMPHLRSNTRGDLHVHVEVVVPTRLD
FT                   HQDIELLRELKGRRDREVAEVRSTHAAAGGLFSRLRETFTGR"
FT   CDS             complement(111133..112164)
FT                   /transl_table=11
FT                   /gene="hrcA"
FT                   /locus_tag="Mb2395c"
FT                   /product="PROBABLE HEAT-INDUCIBLE TRANSCRIPTIONAL REPRESSOR
FT                   HRCA"
FT                   /note="Mb2395c, hrcA, len: 343 aa. Equivalent to Rv2374c,
FT                   len: 343 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 343 aa overlap). Probable hrcA,
FT                   heat-inducible transcriptional repressor, equivalent to
FT                   Q9CCN2|HRCA|ML0624 PUTATIVE HEAT-INDUCIBLE TRANSCRIPTIONAL
FT                   REGULATOR from Mycobacterium leprae (343 aa), FASTA scores:
FT                   opt: 1926, E(): 3.9e-107, (89.8% identity in 343 aa
FT                   overlap). Also highly similar to other heat-inducible
FT                   transcription repressor proteins e.g. Q9RDD6|HRCA|SCC77.22c
FT                   from Streptomyces coelicolor (338 aa), FASTA scores: opt:
FT                   1227, E(): 1.1e-65, (58.8% identity in 335 aa overlap);
FT                   O52163|HRCA_STRAL from Streptomyces albus (338 aa), FASTA
FT                   scores: opt: 1196, E(): 7.7e-64, (56.1% identity in 335 aa
FT                   overlap); P25499|HRCA_BACSU HEAT-INDUCIBLE TRANSCRIPTION
FT                   REPRESSOR from Bacillus subtilis (343 aa), FASTA scores:
FT                   opt: 538, E(): 8.4e-25, (28.9% identity in 325 aa overlap);
FT                   etc. Almost identical, but conflict at C-terminus, to
FT                   Q49749|YGRP|B1937_F1_18 PUTATIVE HEAT-INDUCIBLE
FT                   TRANSCRIPTION REPRESSOR from Mycobacterium leprae (197 aa)
FT                   FASTA scores: opt: 1126, E(): 6.9e-60, (91.8% identity in
FT                   195 aa overlap). BELONGS TO THE HRCA FAMILY."
FT                   /db_xref="GOA:P64399"
FT                   /db_xref="InterPro:IPR011991"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64399"
FT                   /protein_id="CAD97256.1"
FT                   /translation="MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVR
FT                   NDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDL
FT                   DDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRI
FT                   VELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVL
FT                   LESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTV
FT                   RIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVL
FT                   GAR"
FT   CDS             112336..112653
FT                   /transl_table=11
FT                   /gene="Mb2396"
FT                   /locus_tag="Mb2396"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2396, -, len: 105 aa. Equivalent to Rv2375, len:
FT                   105 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 105 aa overlap). Conserved hypothetical
FT                   protein, highly similar to only CAC32314|2SCD60.09c
FT                   CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor
FT                   (98 aa), FASTA scores: opt: 425, E(): 5.7e-24, (63.25%
FT                   identity in 98 aa overlap)."
FT                   /db_xref="InterPro:IPR014447"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYR0"
FT                   /protein_id="CAD97257.1"
FT                   /translation="MIFKGVREGKPYPEHGLSYRDWSQIPPQQIRLDELVTTTTVLALD
FT                   RLLSEDSTFYGDLFPHAVKWRGTTYLEDGLHRAVRAALRNRTVLHARVFDMDASPGGRR
FT                   S"
FT   CDS             complement(112680..113186)
FT                   /transl_table=11
FT                   /gene="cfp2"
FT                   /locus_tag="Mb2397c"
FT                   /standard_name="mtb12"
FT                   /product="LOW MOLECULAR WEIGHT ANTIGEN CFP2 (LOW MOLECULAR
FT                   WEIGHT PROTEIN ANTIGEN 2) (CFP-2)"
FT                   /note="Mb2397c, cfp2, len: 168 aa. Equivalent to Rv2376c,
FT                   len: 168 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 168 aa overlap). cfp2 (alternate gene
FT                   name: mtb12), low molecular weight antigen, secreted
FT                   protein similar to Q49771|MB12_MYCLE|ML0620|B1937_F3_91 LOW
FT                   MOLECULAR WEIGHT ANTIGEN MTB12 HOMOLOG PRECURSOR from
FT                   Mycobacterium leprae (167 aa), FASTA scores: opt: 682, E():
FT                   1.7e-32, (65.5% identity in 165 aa overlap). BELONGS TO THE
FT                   MTB12 FAMILY."
FT                   /db_xref="GOA:P0A5P9"
FT                   /db_xref="InterPro:IPR020235"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5P9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97258.1"
FT                   /translation="MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAP
FT                   LPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAE
FT                   HGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTQNVTFVNQGGWMLSRASAMELL
FT                   QAAGN"
FT   CDS             complement(113286..113501)
FT                   /transl_table=11
FT                   /gene="mbtH"
FT                   /locus_tag="Mb2398c"
FT                   /product="PUTATIVE CONSERVED PROTEIN MBTH"
FT                   /note="Mb2398c, mbtH, len: 71 aa. Equivalent to Rv2377c,
FT                   len: 71 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (98.6% identity in 71 aa overlap). Putative mbtH, conserved
FT                   protein with no function assigned (see first and second
FT                   citation), similar to hypothetical proteins or proteins
FT                   found in several gene clusters for biosynthesis or
FT                   transport of siderophores and other nonribosomally
FT                   synthesized peptides e.g. Q9Z388|SCE8.11c PUTATIVE SMALL
FT                   CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor
FT                   (71 aa), FASTA scores: opt: 345, E(): 1.4e-19, (68.2%
FT                   identity in 66 aa overlap); Q9F8V3|CUMB COUY PROTEIN
FT                   (probably involved in the biosynthesis of aminocoumarin
FT                   antibiotic coumermycin A(1)) (see third citation below)
FT                   from Streptomyces rishiriensis (71 aa), FASTA scores: opt:
FT                   329, E(): 2.2e-18, (63.2% identity in 68 aa overlap);
FT                   Q9F5J2|SIM-CB MBTH-LIKE PROTEIN (probably protein involved
FT                   in the biosynthesis of aminocoumarin antibiotic coumermycin
FT                   A(1)) from Streptomyces antibioticus (70 aa), FASTA scores:
FT                   opt: 308, E(): 8.4e-17, (65.6% identity in 64 aa overlap);
FT                   Q9FB14 MBTH-LIKE PROTEIN (involved in the biosynthesis of
FT                   the antitumor drug bleomycin) (see fourth citation below)
FT                   from Streptomyces verticillus FASTA scores: opt: 220, E():
FT                   8.8e-10, (41.2% identity in 68 aa overlap); etc."
FT                   /db_xref="InterPro:IPR005153"
FT                   /db_xref="UniProtKB/Swiss-Prot:P59965"
FT                   /protein_id="CAD97259.1"
FT                   /translation="MSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASR
FT                   AACLDYVEKNWTDLRPKSLRDAMAED"
FT   CDS             complement(113479..114774)
FT                   /transl_table=11
FT                   /gene="mbtG"
FT                   /locus_tag="Mb2399c"
FT                   /product="LYSINE-N-OXYGENASE MBTG (L-LYSINE
FT                   6-MONOOXYGENASE) (LYSINE N6-HYDROXYLASE)"
FT                   /EC_number="1.14.13.59"
FT                   /note="Mb2399c, mbtG, len: 431 aa. Equivalent to Rv2378c,
FT                   len: 431 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 431 aa overlap). mbtG, lysine-N
FT                   -oxygenase (hydroxylase) (EC 1.14.13.59) showing some
FT                   similarity with various proteins including ornithine and
FT                   lysine-N-oxygenases, e.g. Q9K6Q1|TRKA|BH3677 POTASSIUM
FT                   UPTAKE PROTEIN from Bacillus halodurans (350 aa), FASTA
FT                   scores: opt: 153, E(): 0.016, (25.2% identity in 246 aa
FT                   overlap); P56584|SID1_USTMA L-ORNITHINE 5-MONOOXYGENASE (EC
FT                   1.13.12.-) from Ustilago maydis (Smut fungus) (570 aa),
FT                   FASTA scores: opt: 136, E(): 0.31, (22.85% identity in 127
FT                   aa overlap); Q9HHV0|HXYA|VNG6214G MONOOXYGENASE from
FT                   Halobacterium sp. strain NRC-1 (477 aa), FASTA scores: opt:
FT                   119, E(): 3.4, (40.0% identity in 70 aa overlap);
FT                   O69828|SC1A6.23 PUTATIVE LYSINE N-HYDROXLASE (FRAGMENT)
FT                   from Streptomyces coelicolor (134 aa), BLAST score: 76
FT                   (similarity in part for this one); etc. COFACTORS: FAD (BY
FT                   SIMILARITY)."
FT                   /db_xref="GOA:Q7TYQ9"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYQ9"
FT                   /protein_id="CAD97260.1"
FT                   /translation="MNPTLAVLGAGAKAVAVAAKASVLRDMGVDVPDVIAVERIGVGAN
FT                   WQASGGWTDGAHRLGTSPEKDVGFPYRSALVPRRNAELDERMTRYSWQSYLIATASFAE
FT                   WIDRGRPAPTHRRWSQYLAWVADHIGLKVIHGEVERLAVTGDRWALCTHETTVQADALM
FT                   ITGPGQAEKSLLPGNPRVLSIAQFWDRAAGHDRINAERVAVIGGGETAASMLNELFRHR
FT                   VSTITVISPQVTLFTRGEGFFENSLFSDPTDWAALTFDERRDALARTDRGVFSATVQEA
FT                   LLADDRIHHLRGRVAHAVGRQGQIRLTLSTNRGSENFETVHGFDLVIDGSGADPLWFTS
FT                   LFSQHTLDLLELGLGGPLTADRLQEAIGYDLAVTDVTPKLFLPTLSGLTQGPGFPNLSC
FT                   LGLLSDRVLGAGIFTPTKHNDTRRSGEHQSFR"
FT   CDS             complement(114771..119156)
FT                   /transl_table=11
FT                   /gene="mbtF"
FT                   /locus_tag="Mb2400c"
FT                   /product="PEPTIDE SYNTHETASE MBTF (PEPTIDE SYNTHASE)"
FT                   /note="Mb2400c, mbtF, len: 1461 aa. Equivalent to Rv2379c,
FT                   len: 1461 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 1461 aa overlap). mbtF, peptide
FT                   synthetase (see citations below), similar in part to
FT                   several synthases e.g. O52820|PCZA363.4 PROTEIN from
FT                   Amycolatopsis orientalis (4077 aa), FASTA scores: opt:
FT                   1873, E(): 1.1e-99, (35.55% identity in 1522 aa overlap);
FT                   O07944|SNBDE PRISTINAMYCIN I SYNTHASE 3 AND 4 from
FT                   Streptomyces pristinaespiralis (4848 aa), FASTA scores:
FT                   opt: 1817, E(): 2.1e-96, (33.65% identity in 1463 aa
FT                   overlap); O52821 PROTEIN SIMILAR TO PEPTIDE SYNTHETASE from
FT                   Amycolatopsis orientalis (1860 aa) FASTA scores: opt: 1705,
FT                   E(): 2.9e-90, (34.75% identity in 1344 aa overlap);
FT                   Q9XCF2|PSTB PUTATIVE PEPTIDE SYNTHETASE (similar to
FT                   Mycobacterium tuberculosis nrp protein) from Mycobacterium
FT                   avium (2552 aa), FASTA scores: opt: 1687, E(): 4e-89,
FT                   (35.45% identity in 1058 aa overlap); Q9ZET7 PEPTIDE
FT                   SYNTHETASE (FRAGMENT) from Mycobacterium smegmatis (1438
FT                   aa), FASTA scores: opt: 1479, E(): 2.5e-77, (30.45%
FT                   identity in 1507 aa overlap); etc. Contains PS00455
FT                   putative AMP-binding domain signature. BELONGS TO THE
FT                   ATP-DEPENDENT AMP-BINDING ENZYME FAMILY."
FT                   /db_xref="GOA:Q7TYQ8"
FT                   /db_xref="HSSP:1AMU"
FT                   /db_xref="InterPro:IPR010071"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ8"
FT                   /protein_id="CAD97261.1"
FT                   /translation="MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAE
FT                   ADPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSAEVLW
FT                   RHVRAHPSEVGALAAEERRRRFDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGWSLP
FT                   LFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLS
FT                   PALADTPVQPGIPGRTEVRLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGD
FT                   VTFGVTVSGRPSELSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSY
FT                   LGFNEFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVA
FT                   AHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDP
FT                   TAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAVSWADGQLTYRELDALADRLATGLRRAD
FT                   VSRETPVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERVAEILRQTSAPVVIDEG
FT                   VFAASVGADILEDDRAITVPVDQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVL
FT                   RPAAQRLGRPLRIAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFG
FT                   LDMIDTTPSMFAQLHNAGLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYG
FT                   PTETTVEAVVAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGY
FT                   LGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKIRGFRVEPGEI
FT                   AAVLNGHHAVHGCHVTARGHASGPRLTAYVAGGPQPPPVAELRAMLLERLPRYLVPHHI
FT                   VVLDELPLTPHGKIDENALAAINVTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGF
FT                   LQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPANDAGEPI
FT                   PVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRCRFDRDAMA
FT                   LVAQPKTDILSEVWVSGELVTAVAEQTLGVLASLDPQAGRLLSAVWLREPDGPGVLVLT
FT                   AHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDSVDF
FT                   WVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLSTGRSMTDLLATAAAR
FT                   MVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVGLLSAIYPLRIHCDGATDF
FT                   ARIPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVGDLAVDRALLADVGQ
FT                   LPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDILSADDVATLQSLWQGALAEITA
FT                   "
FT   CDS             complement(119138..124186)
FT                   /transl_table=11
FT                   /gene="mbtE"
FT                   /locus_tag="Mb2401c"
FT                   /product="PEPTIDE SYNTHETASE MBTE (PEPTIDE SYNTHASE)"
FT                   /note="Mb2401c, mbtE, len: 1682 aa. Equivalent to Rv2380c,
FT                   len: 1682 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 1682 aa overlap). mbtE, peptide
FT                   synthetase (see citations below), similar in part to
FT                   several synthases e.g. O07944|SNBDE PRISTINAMYCIN I
FT                   SYNTHASE 3 AND 4 from Streptomyces pristinaespiralis (4848
FT                   aa), FASTA scores: opt: 2635, E(): 1.9e-146, (36.8%
FT                   identity in 1657 aa overlap); O05647|SNBDE VIRGINIAMYCIN S
FT                   SYNTHETASE (FRAGMENT) from Streptomyces virginiae (1997 aa)
FT                   FASTA scores: opt: 2580, E(): 1.6e-143, (40.65% identity in
FT                   1163 aa overlap); Q9R9I2|DHBF PROTEIN INVOLVED IN
FT                   SIDEROPHORE PRODUCTION from Bacillus subtilis (2378 aa),
FT                   FASTA scores: opt: 2388, E(): 3.6e-132, (33.9% identity in
FT                   1579 aa overlap); O68487|ACMB ACTINOMYCIN SYNTHETASE II
FT                   from Streptomyces chrysomallus (2611 aa), FASTA scores:
FT                   opt: 2165, E(): 4.9e-119, (35.0% identity in 1634 aa
FT                   overlap); etc. Equivalent to AAK46743 from Mycobacterium
FT                   tuberculosis strain CDC1551 (1787 aa) but shorter 105 aa.
FT                   Contains PS00455 putative AMP-binding domain signature, and
FT                   PS00012 Phosphopantetheine attachment site. BELONGS TO THE
FT                   ATP-DEPENDENT AMP-BINDING ENZYME FAMILY."
FT                   /db_xref="GOA:Q7TYQ7"
FT                   /db_xref="HSSP:1AMU"
FT                   /db_xref="InterPro:IPR010071"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ7"
FT                   /protein_id="CAD97262.1"
FT                   /translation="MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRIL
FT                   RTTYPVGDDGVAQPTVHADLRPGWTQYDLTDLSQRAQRLRLEVLAQREFCAPFELSRDA
FT                   PLRITVVRTAADEHVLLLVAHHIAWDDGSWRVFFTDLTQAYSRADLGADLGPEHRPSAA
FT                   SGPDTTEADLNYWRAIMADPPEPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMA
FT                   KNTGCTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQ
FT                   SAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDRRHGAERMTRVSFGFREPDGGG
FT                   FNPPGIECERYDLRSNITQLPLGFMVEFDRAGVLVEAEHLVEILEPALAKQMLRHFGVL
FT                   LDNALAAPDNTLSGLALMDERDAARLREVSRGERFDTPVKTLVDLVNEQTTRTPDATAV
FT                   VYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYV
FT                   PVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSDDPTDADRIRPLRPDNTAYLIYT
FT                   SGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDRLLQVASPSFDVSIAEIFGTLACGA
FT                   RMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEP
FT                   LPGEVADKFHATFDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLD
FT                   DSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNAD
FT                   GDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPA
FT                   AGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAALPEPQIAS
FT                   DTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDV
FT                   GVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLSSSQMRSWFNYRFDGPNA
FT                   VNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGVPHQIIQPPAEVPVRCA
FT                   AGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLVVHHIAGDHWSAGVLF
FT                   TDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGPQRDYWIRQLGGLAG
FT                   ETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKA
FT                   GGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYA
FT                   HQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGDTTLRVLEPTFD
FT                   AAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFADRPDQPLREVE
FT                   MVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVGARLARPSET
FT                   ATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPAEPADTETE
FT                   RALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVFEHPVLCE
FT                   LAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP"
FT   CDS             complement(124326..127340)
FT                   /transl_table=11
FT                   /gene="mbtD"
FT                   /locus_tag="Mb2402c"
FT                   /product="POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE)"
FT                   /note="Mb2402c, mbtD, len: 1004 aa. Equivalent to Rv2381c,
FT                   len: 1004 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 1004 aa overlap). mbtD, polyketide
FT                   synthase (see citations below), similar in part to several
FT                   synthases e.g. Q03132|ERY2_SACER|ERYA ERYTHRONOLIDE
FT                   SYNTHASE, MODULES 3 AND 4 (EC 2.3.1.94) from
FT                   Saccharopolyspora erythraea (Streptomyces erythraeus) (3567
FT                   aa), FASTA scores: opt: 971, E(): 1e-46, (29.35% identity
FT                   in 1043 aa overlap); Q9F829|MEGAII MEGALOMICIN
FT                   6-DEOXYERYTHRONOLIDE B SYNTHASE 2 from Micromonospora
FT                   megalomicea subsp. nigra (3562 aa), FASTA scores: opt: 787,
FT                   E(): 2.4e-36, (29.35% identity in 1032 aa overlap);
FT                   Q9L4W4|NYSB POLYKETIDE SYNTHASE from Streptomyces noursei
FT                   (3192 aa), FASTA scores: opt: 761, E(): 6.6e-35, (29.55%
FT                   identity in 1086 aa overlap); O30764|NIDA1 POLYKETIDE
FT                   SYNTHASE MODULES 1 AND 2 from Streptomyces caelestis (4340
FT                   aa), FASTA scores: opt: 726, E(): 7.8e-33, (27.3% identity
FT                   in 1052 aa overlap); etc. Contains PS00012
FT                   Phosphopantetheine attachment site."
FT                   /db_xref="GOA:Q7TYQ6"
FT                   /db_xref="InterPro:IPR016040"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ6"
FT                   /protein_id="CAD97263.1"
FT                   /translation="MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEV
FT                   ARQLRKTRRVRRHRAVLRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQAFVFPGQ
FT                   GGHWPGMGAVAYRELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIE
FT                   GAQFVHAVALAEVWRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGR
FT                   LPGRYAVAALGIGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSG
FT                   HFARGITVGFPVHTSVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYW
FT                   YANLRHTVRFDRAVESAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSA
FT                   RRGERFVDALSANIVSAAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEP
FT                   LPPVSGLTIAVERWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSA
FT                   ARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQVD
FT                   AADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETA
FT                   LRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRI
FT                   VLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSV
FT                   ISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSA
FT                   ANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQ
FT                   QAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAAVLG
FT                   IPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDA
FT                   DERSHTAQKVDISRD"
FT   CDS             complement(127340..128674)
FT                   /transl_table=11
FT                   /gene="mbtC"
FT                   /locus_tag="Mb2403c"
FT                   /product="POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE)"
FT                   /note="Mb2403c, mbtC, len: 444 aa. Equivalent to Rv2382c,
FT                   len: 444 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 444 aa overlap). mbtC, polyketide
FT                   synthase (see citations below), similar in part to several
FT                   synthases e.g. Q9F7T9 AVERMECTIN POLYKETIDE SYNTHASE
FT                   (FRAGMENT) from Streptomyces avermitilis (3626 aa), FASTA
FT                   scores: opt: 1458, E(): 7e-82, (50.65% identity in 446 aa
FT                   overlap); AAG23264|SPNA POLYKETIDE SYNTHASE LOADING AND
FT                   EXTENDER MODULE 1 from Saccharopolyspora spinosa (2595 aa)
FT                   FASTA scores: opt: 1441, E(): 6e-81, (49.1% identity in 446
FT                   aa overlap); O33954|TYLG TYLACTONE SYNTHASE STARTER MODULE
FT                   AND MODULES 1 & 2 from Streptomyces fradiae (4472 aa) FASTA
FT                   scores: opt: 1439, E(): 1.2e-80, (51.0% identity in 447 aa
FT                   overlap); O30764|NIDA1 POLYKETIDE SYNTHASE MODULES 1 AND 2
FT                   from Streptomyces caelestis (4340 aa) FASTA scores: opt:
FT                   1432, E(): 3.3e-80, (50.9% identity in 442 aa overlap);
FT                   etc."
FT                   /db_xref="GOA:Q7TYQ5"
FT                   /db_xref="InterPro:IPR014030"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ5"
FT                   /protein_id="CAD97264.1"
FT                   /translation="MSDNDPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRG
FT                   WALRELFDGSRRNGFKPIHNLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWR
FT                   TLENSGINPDDLAGHDVGCYVGASALEYGPALTEFSHHSGHLITGTSLGVISGRIAYTL
FT                   DLAGPALTVDTSCSSALAAFHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALS
FT                   DDGHCRPYSAHASGTAWAEGAAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTA
FT                   PSGDAQTRLLRRAIAQAAVVPADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPL
FT                   LGSVKSNIGHAQAAAGGLGLVKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLT
FT                   PWRAVDGWRTAAVSAFGMSGTNSHVIVSMPDTVSAPERGPECGEV"
FT   CDS             complement(128664..132908)
FT                   /transl_table=11
FT                   /gene="mbtB"
FT                   /locus_tag="Mb2404c"
FT                   /product="PHENYLOXAZOLINE SYNTHASE MBTB (PHENYLOXAZOLINE
FT                   SYNTHETASE)"
FT                   /note="Mb2404c, mbtB, len: 1414 aa. Equivalent to Rv2383c,
FT                   len: 1414 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.9% identity in 1414 aa overlap). mbtB, phenyloxazoline
FT                   synthase (see citations below), similar to the N-terminal
FT                   region of several synthetases e.g. Q9EWP5|SC4C2.17 PUTATIVE
FT                   NON-RIBOSOMAL PEPTIDE SYNTHASE from Streptomyces coelicolor
FT                   (2229 aa), FASTA scores: opt: 2878, E(): 4.1e-156, (46.85%
FT                   identity in 1138 aa overlap); Q9Z399|IRP2 YERSINIABACTIN
FT                   BIOSYNTHETIC from Yersinia pestis (2041 aa), FASTA scores:
FT                   opt: 2297, E(): 5.3e-123, (38.55% identity in 1069 aa
FT                   overlap); P48633|HMP2_YEREN|IRP2 HIGH-MOLECULAR-WEIGHT
FT                   PROTEIN 2 (MAY BE INVOLVED IN THE NONRIBOSOMAL SYNTHESIS OF
FT                   SMALL PEPTIDES) from Yersinia enterocolitica (2035 aa),
FT                   FASTA scores: opt: 2275, E(): 9.4e-122, (38.45% identity in
FT                   1069 aa overlap); O85739|PCHE|PA4226 DIHYDROAERUGINOIC ACID
FT                   SYNTHETASE from Pseudomonas aeruginosa (1438 aa) FASTA
FT                   scores: opt: 2236, E(): 1.2e-119, (38.2% identity in 1330
FT                   aa overlap); Q9RFM8|PCHE PYOCHELIN SYNTHETASE from
FT                   Pseudomonas aeruginosa (1438 aa), FASTA scores: opt: 2229,
FT                   E(): 3e-119, (38.0% identity in 1329 aa overlap); etc.
FT                   Contains PS00455 Putative AMP-binding domain signature, and
FT                   PS00012 Phosphopantetheine attachment site. BELONGS TO THE
FT                   ATP-DEPENDENT AMP-BINDING ENZYME FAMILY."
FT                   /db_xref="GOA:Q7TYQ4"
FT                   /db_xref="HSSP:1DNY"
FT                   /db_xref="InterPro:IPR001031"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYQ4"
FT                   /protein_id="CAD97265.1"
FT                   /translation="MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSL
FT                   VGRWRRKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAP
FT                   MQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGT
FT                   QRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGER
FT                   TRLHVDLDMQAADAMSYRILLADLAALYDGREPPALGYTYQEYRQAIEAEETLPQPVRD
FT                   ADRDWWAQRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPA
FT                   MTLAAAFANVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTA
FT                   AARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTE
FT                   QFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLA
FT                   AGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSG
FT                   DLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVD
FT                   QPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAY
FT                   VLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAAL
FT                   RSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVG
FT                   GDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFP
FT                   NNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLA
FT                   RYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAV
FT                   CVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERS
FT                   GDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRW
FT                   LDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPI
FT                   EQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQR
FT                   ADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRA
FT                   LWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRA
FT                   LSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHL
FT                   DAVARMVSADVR"
FT   CDS             133007..134704
FT                   /transl_table=11
FT                   /gene="mbtA"
FT                   /locus_tag="Mb2405"
FT                   /product="BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE
FT                   (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE"
FT                   /EC_number="6.-.-.-"
FT                   /note="Mb2405, mbtA, len: 565 aa. Equivalent to Rv2384,
FT                   len: 565 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 565 aa overlap). mbtA, bifunctional
FT                   enzyme, including salicyl-AMP ligase (Sal-AMP ligase) (EC
FT                   6.-.-.-) and salicyl-S-ArCP synthetase (see first and
FT                   second citations below), highly similar to other ligases
FT                   e.g. Q9F638|MXCE from Stigmatella aurantiaca 2,3-DHBA-AMP
FT                   ligase (protein involved in the biosynthesis of
FT                   2,3-dihydroxybenzoic acid, contains the AMP binding
FT                   signature) (543 aa), FASTA scores: opt: 1683, E(): 2.8e-90,
FT                   (48.25% identity in 545 aa overlap) (see third citation
FT                   below); P40871|DHBE_BACSU|ENTE 2,3-DIHYDROXYBENZOATE-AMP
FT                   LIGASE (EC 6.3.2.-) from Bacillus subtilis (539 aa), FASTA
FT                   scores: opt: 1569, E(): 1.2e-83, (44.9% identity in 532 aa
FT                   overlap); O07899|VIBE_VIBCHVC0772 VIBRIOBACTIN-SPECIFIC
FT                   2,3-DIHYDROXYBENZOATE-AMP LIGASE from Vibrio cholerae (543
FT                   aa), FASTA scores: opt: 1457, E(): 3.7e-77, (44.6% identity
FT                   in 545 aa overlap); etc. Also similar to P95819|SNBA
FT                   PRISTINAMYCIN I SYNTHETASE I from Streptomyces
FT                   pristinaespiralis (582 aa), FASTA scores: opt: 1532, E():
FT                   1.7e-81, (46.35% identity in 548 aa overlap); and
FT                   Q9RFM9|PCHD SALICYL-AMP LIGASE from Pseudomonas aeruginosa
FT                   (547 aa), FASTA scores: opt: 1415, E(): 1e-74, (45.95%
FT                   identity in 533 aa overlap). Contains PS00455 Putative
FT                   AMP-binding domain signature. BELONGS TO THE ATP-DEPENDENT
FT                   AMP-BINDING ENZYME FAMILY."
FT                   /db_xref="GOA:Q7TYQ3"
FT                   /db_xref="InterPro:IPR000873"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ3"
FT                   /protein_id="CAD97266.1"
FT                   /translation="MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTV
FT                   LSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPN
FT                   GCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARE
FT                   LVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKL
FT                   IPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPD
FT                   PSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARR
FT                   VRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPG
FT                   EEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICR
FT                   AGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDR
FT                   RGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIATGPVTTQRCH"
FT   CDS             134800..135720
FT                   /transl_table=11
FT                   /gene="mbtJ"
FT                   /locus_tag="Mb2406"
FT                   /product="PUTATIVE ACETYL HYDROLASE MBTJ"
FT                   /EC_number="3.1.1.-"
FT                   /note="Mb2406, mbtJ, len: 306 aa. Equivalent to Rv2385,
FT                   len: 306 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 306 aa overlap). Putative mbtJ, acetyl
FT                   hydrolase (EC 3.1.1.-) (see citations below), showing some
FT                   similarity with various hydrolases including acetyl
FT                   hydrolases e.g. Q9ZBM4|MLCB1450.08|ML0314 PUTATIVE
FT                   HYDROLASE/ESTERASE from Mycobacterium leprae (335 aa),
FT                   FASTA scores: opt: 449, E(): 6.7e-21, (33.85% identity in
FT                   313 aa overlap); AAK47950|MT3591 Esterase from M.
FT                   tuberculosis strain CDC1551 (327 aa), FASTA scores: opt:
FT                   469, E(): 3.6e-22, (35% identity in 283 aa overlap);
FT                   Q9X8J4|SCE9.22 PUTATIVE ESTERASE from Streptomyces
FT                   coelicolor (266 aa), FASTA scores: opt: 430,E(): 8.5e-20,
FT                   (38% identity in 245 aa overlap); Q01109|BAH_STRHY
FT                   ACETYL-HYDROLASE (EC 3.1.1.-) from Streptomyces
FT                   hygroscopicus (299 aa), FASTA scores: opt: 420, E(): 4e-19,
FT                   (35.1% identity in 265 aa overlap). Equivalent to AAK46748
FT                   from Mycobacterium tuberculosis strain CDC1551 (327 aa) but
FT                   shorter 21 aa. Note that previously known as lipK."
FT                   /db_xref="GOA:Q7TYQ2"
FT                   /db_xref="InterPro:IPR013094"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ2"
FT                   /protein_id="CAD97267.1"
FT                   /translation="MVLRPITGAIPPDGPWGIWASRRIIAGLMGTFGPSLAGTRVEQVN
FT                   SVLPDGRRVVGEWVYGPHNNAINAGPGGGAIYYVHGSGYTMCSPRTHRRLTSWLSSLTG
FT                   LPVFSVDYRLAPRYRFPTAATDVRAAWDWLAHVCGLAAEHMVIAADSAGGHLTVDMLLQ
FT                   PEVAARPPAAVVLFSPLIDLTFRLGASRELQRPDPVVRADRAARSVALYYTGVDPAHHR
FT                   LALDVAGGPPLPPTLIQVGGAEILEADARQLDADIRAAGGICELQVWPDQMHVFQALPR
FT                   MTPEAAKAMTYVAQFIRSTTARGDL"
FT   CDS             complement(135724..137076)
FT                   /transl_table=11
FT                   /gene="mbtI"
FT                   /locus_tag="Mb2407c"
FT                   /product="PUTATIVE ISOCHORISMATE SYNTHASE MBTI"
FT                   /note="Mb2407c, mbtI, len: 450 aa. Equivalent to Rv2386c,
FT                   len: 450 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 450 aa overlap). Putative mbtI,
FT                   isochorismate synthase (see citations below), similar to
FT                   Q9X9I8|IRP9 SALICYLATE SYNTHETASE from Yersinia
FT                   enterocolitica (434 aa), FASTA scores: opt: 887, E():
FT                   7.5e-48, (37.45% identity in 422 aa overlap); and similar
FT                   in C-terminal region to many anthranilate synthases
FT                   component I (EC 4.1.3.27) e.g. Q9Z4W7|TRPE_STRCO|SCE8.07c
FT                   from Streptomyces coelicolor (511 aa), FASTA scores: opt:
FT                   509, E(): 3e-24, (40.4% identity in 255 aa overlap);
FT                   P33975|TRPE_HALVO from Halobacterium volcanii (Haloferax
FT                   volcanii) (523 aa) FASTA scores: opt: 488, E(): 6.2e-23,
FT                   (34.2% identity in 298 aa overlap); and similar to
FT                   Q08653|TRPE_THEMA|TM0142 ANTHRANILATE SYNTHASE COMPONENT I
FT                   from Thermotoga maritima (461 aa), FASTA scores: opt: 478,
FT                   E(): 2.3e-22, (28.4% identity in 440 aa overlap); etc.
FT                   COULD BE BELONG TO THE ANTHRANILATE SYNTHASE COMPONENT I
FT                   FAMILY. Note that previously known as trpE2, an
FT                   anthranilate synthase component I (EC 4.1.3.27)."
FT                   /db_xref="GOA:Q7TYQ1"
FT                   /db_xref="HSSP:1K0G"
FT                   /db_xref="InterPro:IPR019996"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYQ1"
FT                   /protein_id="CAD97268.1"
FT                   /translation="MSELSVATGAVSTASSSIPMPAGVNPADLAAELAAVVTESVDEDY
FT                   LLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETD
FT                   QAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDR
FT                   LLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPL
FT                   TYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRALGRGPAID
FT                   RLARDDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRERGSVQHLGSTIR
FT                   ARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLD
FT                   AALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVARQ"
FT   CDS             137836..139089
FT                   /transl_table=11
FT                   /gene="Mb2408"
FT                   /locus_tag="Mb2408"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2408, -, len: 417 aa. Equivalent to Rv2387, len:
FT                   417 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 417 aa overlap). Conserved hypothetical
FT                   protein, showing some similarities with others e.g.
FT                   Q9K663|BH3869 HYPOTHETICAL PROTEIN from Bacillus halodurans
FT                   (337 aa), FASTA scores: opt: 343, E(): 4.8e-14, (29.0%
FT                   identity in 400 aa overlap); AAK25471|CC3509 HYPOTHETICAL
FT                   PROTEIN from Caulobacter crescentus (365 aa), FASTA scores:
FT                   opt: 282, E(): 3.2e-10, (32.6% identity in 399 aa overlap);
FT                   P73953|SLR1512 [D90911_21] CONSERVED HYPOTHETICAL PROTEIN
FT                   from Synechocystis sp. strain PCC6803 (374 aa), FASTA
FT                   scores: opt: 230, E(): 5.5e-07; (24.75% identity in 408 aa
FT                   overlap); etc. Contains PS00213 Lipocalin signature."
FT                   /db_xref="InterPro:IPR002345"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYQ0"
FT                   /protein_id="CAD97269.1"
FT                   /translation="MLHEFWVNFTHNLFKPLLLFFYFGFLIPIFKVRFEFPYVLYQGLT
FT                   LYLLLAIGWHGGEELAKIKPSNVGAIVGFMVVGFALNFVIGTLAYFLLSKLTAMRRVDR
FT                   ATVAGYYGSDSAGTFATCVAVLTSVGMAFDAYMPVMLAVMEIPGCLVALYLVARLRHRG
FT                   MNEAGYMADEPGYTTAAMIGAGPGTPARPAHSDSLTAQAERGIEEELELSLEKREHPNW
FT                   DEDGVKDSGTNASIFSRELLQEVFLNPGLVLLFGGIVIGLISGLQGQKVLHDDDNFFVA
FT                   AFQGVLCLFLLEMGMTASRKLKDLASAGSGFVFFGLLAPNLFATLGIIVAHGYAYVTNN
FT                   DFAPGTYVLFAVLCGAASYIAVPAVQRLAIPEASPTLPLAASLGLTFSYNVTIGIPLYI
FT                   EIARIVGQWFPATGASIG"
FT   CDS             complement(139086..140213)
FT                   /transl_table=11
FT                   /gene="hemN"
FT                   /locus_tag="Mb2409c"
FT                   /product="PROBABLE OXYGEN-INDEPENDENT COPROPORPHYRINOGEN
FT                   III OXIDASE HEMN (COPROPORPHYRINOGENASE) (COPROGEN
FT                   OXIDASE)"
FT                   /EC_number="1.3.3.-"
FT                   /note="Mb2409c, hemN, len: 375 aa. Equivalent to Rv2388c,
FT                   len: 375 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 375 aa overlap). Probable hemN,
FT                   oxygen-independent coproporphyrinogen III oxidases (EC
FT                   1.3.3.-), highly similar to many PUTATIVE
FT                   OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASES e.g.
FT                   Q9RDD2|SCC77.26 from Streptomyces coelicolor (435 aa),
FT                   FASTA scores: opt: 1358, E(): 1.5e-76, (56.55% identity in
FT                   382 aa overlap); BAB51237|MLR4627 from Rhizobium loti
FT                   (Mesorhizobium loti) (392 aa), FASTA scores: opt: 696, E():
FT                   1.1e-35, (36.8% identity in 383 aa overlap); Q9KUR0|VC0455
FT                   from Vibrio cholerae (391 aa), FASTA scores: opt: 691,
FT                   2.2e-35, (32.65% identity in 386 aa overlap);
FT                   P54304|HEMN_BACSU from Bacillus subtilis (366 aa), FASTA
FT                   scores: opt: 668 , E(): 5.6e-34; (34.9% identity in 327 aa
FT                   overlap); etc. Equivalent to AAK46752 from Mycobacterium
FT                   tuberculosis strain CDC1551 (390 aa) but shorter 375 aa.
FT                   BELONGS TO THE ANAEROBIC COPROPORPHYRINOGEN III OXIDASE
FT                   FAMILY."
FT                   /db_xref="GOA:Q7TYP9"
FT                   /db_xref="InterPro:IPR007197"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP9"
FT                   /protein_id="CAD97270.1"
FT                   /translation="MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALR
FT                   AELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPE
FT                   STWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNL
FT                   DLIYGTPGESDDDLVRSVDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVL
FT                   AHRYELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRW
FT                   WNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERA
FT                   EAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG"
FT   CDS             complement(140319..140783)
FT                   /transl_table=11
FT                   /gene="rpfD"
FT                   /locus_tag="Mb2410c"
FT                   /product="PROBABLE RESUSCITATION-PROMOTING FACTOR RPFD"
FT                   /note="Mb2410c, rpfD, len: 154 aa. Equivalent to Rv2389c,
FT                   len: 154 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 154 aa overlap). Probable rpfD,
FT                   resuscitation-promoting factor. Possible autocrine and/or
FT                   paracrine bacterial growth factor or cytokine (see citation
FT                   below). Similar to others from Mycobacterium tuberculosis
FT                   e.g. O07747|Rv1884c|MTCY180.34|RPFC PROBABLE
FT                   RESUSCITATION-PROMOTING FACTOR from Mycobacterium
FT                   tuberculosis (176 aa), FASTA scores: opt: 382, E():
FT                   2.3e-17, (55.45% identity in 101 aa overlap); etc. Also
FT                   similarity with Q9CBF8|ML2030 HYPOTHETICAL PROTEIN from
FT                   Mycobacterium leprae (157 aa), FASTA scores: opt: 397, E():
FT                   2.4e-18, (47.95% identity in 121 aa overlap);
FT                   Q9F2Q2|SCE41.06c PUTATIVE SECRETED PROTEIN from
FT                   Streptomyces coelicolor (244 aa), FASTA scores: opt: 341,
FT                   E(): 1.1e-14, (40.45% identity in 131 aa overlap); and
FT                   O86308|Z96935|MLRPF_1 RPF PROTEIN PRECURSOR from
FT                   Micrococcus luteus (220 aa), FASTA scores: opt: 301, E():
FT                   3.6e-12, (39.4% identity in 132 aa overlap). Contains a
FT                   secretory signal sequence in N-terminus. Supposed acts at
FT                   very low concentration."
FT                   /db_xref="GOA:Q7TYP8"
FT                   /db_xref="InterPro:IPR010618"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP8"
FT                   /protein_id="CAD97271.1"
FT                   /translation="MTPGLLTTAGAGRPRDRCARIVCTVFIETAVVATMFVALLGLSTI
FT                   SSKADDIDWDAIAQCESGGNWAANTGNGLYGGLQISQATWDSNGGVGSPAAASPQQQIE
FT                   VADNIMKTQGPGAWPKCSSCSQGDAPLGSLTHILTFLAAETGGCSGSRDD"
FT   CDS             complement(140780..141337)
FT                   /transl_table=11
FT                   /gene="Mb2411c"
FT                   /locus_tag="Mb2411c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2411c, -, len: 185 aa. Equivalent to Rv2390c, len:
FT                   185 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.5% identity in 185 aa overlap). Conserved hypothetical
FT                   protein, similar to other Mycobacterium tuberculosis
FT                   proteins Q11032|YD62_MYCTU|MTCY02B10.26c|Rv1362c
FT                   hypothetical 23.5 kd protein (220 aa), FASTA scores: opt:
FT                   223, E(): 2.1e-07, (27.4% identity in 190 aa overlap); and
FT                   Q11033|YD63_MYCTU|MTCY02B10.27c|Rv1363c hypothetical 28.3
FT                   kd protein (261 aa), FASTA scores: opt: 238, E(): 2.7e-08,
FT                   (27.6% identity in 163 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP7"
FT                   /protein_id="CAD97272.1"
FT                   /translation="MAIFGRGHGASEPGGTGEPAETPGRGRLTRSVTGWVGAVAVVVSL
FT                   AGSGWCGWVLFEKHQTDVAAGQALQAARSYVVKLATMDCERIDHNMRDILEGSTGEFKD
FT                   KYGKSSAHLRQLLADNRVATHGTVVAASVKSATTNKVVVLMFIDQSVSNRNSPTPQIDR
FT                   SRIKVIMDKVNGRWLASKVELL"
FT   CDS             141750..143441
FT                   /transl_table=11
FT                   /gene="nirA"
FT                   /locus_tag="Mb2412"
FT                   /product="PROBABLE FERREDOXIN-DEPENDANT NITRITE REDUCTASE
FT                   NIRA"
FT                   /EC_number="1.7.7.1"
FT                   /note="Mb2412, nirA, len: 563 aa. Equivalent to Rv2391,
FT                   len: 563 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 563 aa overlap). Probable nirA,
FT                   ferredoxin-dependant nitrite reductase (EC 1.7.7.1),
FT                   similar to many nitrate reductases e.g.
FT                   CAC33947|SCBAC1A6.26c Putative nitrite/sulphite reductase
FT                   from Streptomyces coelicolor (565 aa), FASTA scores: opt:
FT                   2335, E(): 1.2e-137, (60.1% identity in 567 aa overlap);
FT                   Q9RZD6|DRA0013 FERREDOXIN-NITRITE REDUCTASE from
FT                   Deinococcus radiodurans (563 aa), FASTA scores: opt: 1141,
FT                   E(): 2.2e-63, (39.6% identity in 533 aa overlap);
FT                   Q59656|NIRA (D31732|PEENIRNRT_1) ferredoxin-dependant*
FT                   NITRITE REDUCTASE (*: see citation below) from Plectonema
FT                   boryanum (654 aa), FASTA scores: opt: 805, E(): 1.9e-42,
FT                   (31.7% identity in 517 aa overlap); Q55366|NIRA|SLR0898
FT                   FERREDOXIN-NITRITE REDUCTASE from Synechocystis sp. strain
FT                   PCC 6803 (502 aa), FASTA scores: opt: 799, E(): 3.7e-42,
FT                   (32.3% identity in 517 aa overlap). Highly similar (only in
FT                   N-terminal part because shortened protein (fragment) owing
FT                   to an IS900 insertion) to Q9K541|NIRA NITRATE REDUCTASE
FT                   (FRAGMENT) from Mycobacterium paratuberculosis (198 aa),
FT                   FASTA scores: opt: 798, E(): 2.1e-42, (65.4% identity in
FT                   182 aa overlap)."
FT                   /db_xref="GOA:Q7TYP6"
FT                   /db_xref="InterPro:IPR005117"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYP6"
FT                   /protein_id="CAD97273.1"
FT                   /translation="MSAKENPQMTTARPAKARNEGQWALGHREPLNANEELKKAGNPLD
FT                   VRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYDGTWTGDDNIDKLEAKYFMM
FT                   RVRCDGGALSAAALRTLGQISTEFARDTADISDRQNVQYHWIEVENVPEIWRRLDDVGL
FT                   QTTEACGDCPRVVLGSPLAGESLDEVLDPTWAIEEIVRRYIGKPDFADLPRKYKTAISG
FT                   LQDVAHEINDVAFIGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAV
FT                   TSVFRDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHV
FT                   GVQRLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTPYQKLVILDIPDALL
FT                   DDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSFAETRVRAQHLVPELERRLEDINS
FT                   QLDVPITVNINGCPNSCARIQIADIGFKGQMIDDGHGGSVEGFQVHLGGHLGLDAGFGR
FT                   KLRQHKVTSDELGDYIDRVVRNFVKHRSEGERFAQWVIRAEEDDLR"
FT   CDS             143438..144202
FT                   /transl_table=11
FT                   /gene="cysH"
FT                   /locus_tag="Mb2413"
FT                   /product="PROBABLE 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE
FT                   REDUCTASE CYSH (PAPS REDUCTASE, THIOREDOXIN DEP.) (PADOPS
FT                   REDUCTASE) (3'-PHOSPHOADENYLYLSULFATE REDUCTASE) (PAPS
FT                   SULFOTRANSFERASE)."
FT                   /EC_number="1.8.4.8"
FT                   /note="Mb2413, cysH, len: 254 aa. Equivalent to Rv2392,
FT                   len: 254 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 254 aa overlap). Probable cysH,
FT                   3'-phosphoadenosine 5'-phosphosulfate reductase (EC
FT                   1.8.4.8), similar to many e.g.
FT                   P94498|O34620|CYH1_BACSU|CYSH from Bacillus subtilis (233
FT                   aa), FASTA scores: opt: 618, E(): 8.1e-32, (46.5% identity
FT                   in 202 aa overlap); Q9KCT3|CYSH|BH1486 from Bacillus
FT                   halodurans (231 aa), FASTA scores: opt: 560, E(): 3.6e-28,
FT                   (41.3% identity in 230 aa overlap); P56860|CYSH_DEIRA from
FT                   Deinococcus radiodurans (255 aa), FASTA scores: opt: 489,
FT                   E(): 1.1e-23, (44.7% identity in 190 aa overlap); etc.
FT                   BELONGS TO THE PAPS REDUCTASE FAMILY and CYSH SUBFAMILY.
FT                   Note that operon cysA-cysW-cysT-subI, probably involved in
FT                   sulfate transport, is near this putative ORF."
FT                   /db_xref="GOA:P65669"
FT                   /db_xref="InterPro:IPR002500"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65669"
FT                   /protein_id="CAD97274.1"
FT                   /translation="MSGETTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIGG
FT                   AGGGVSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAI
FT                   ESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGL
FT                   RRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIG
FT                   CAPCTAKPAEGADPRSGRWQGLAKTECGLHAS"
FT   CDS             144199..145044
FT                   /transl_table=11
FT                   /gene="Mb2414"
FT                   /locus_tag="Mb2414"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2414, -, len: 281 aa. Equivalent to Rv2393, len:
FT                   281 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 281 aa overlap). Conserved hypothetical
FT                   protein, with some similarity to Q9L2E8|SC7A8.10c PUTATIVE
FT                   SECRETED PROTEIN from Streptomyces coelicolor (274 aa),
FT                   FASTA scores: opt: 407, E(): 2.8e-18, (37% identity in 246
FT                   aa overlap); CAC38793|SCI39.05 Conserved hypothetical
FT                   protein from Streptomyces coelicolor (305 aa), FASTA
FT                   scores: opt: 394, E(): 2e-17, (35.0% identity in 251 aa
FT                   overlap); AAK44492|MT0272 Chalcone/stilbene synthase family
FT                   protein from Mycobacterium tuberculosis (247 aa), FASTA
FT                   scores: opt: 350, E(): 9.2e-15, (34.0% identity in 235 aa
FT                   overlap); P95216|Rv0259c|MTCY06A4.03c|Z86089 hypothetical
FT                   protein from Mycobacterium tuberculosis (247 aa), FASTA
FT                   scores: opt: 345, E(): 1.9e-14,(33.6% identity in 235 aa
FT                   overlap)."
FT                   /db_xref="GOA:Q7TYP5"
FT                   /db_xref="InterPro:IPR002762"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP5"
FT                   /protein_id="CAD97275.1"
FT                   /translation="MTAPATMQSAAMLRSGAIEAPPATMQSAAMRWGHLPLAEESGTIA
FT                   PQLVLTAHGSKDPRSAANARAIAGRLARMRPGLDVRVAFCELNSPNLVDVLNRCRGAAV
FT                   VTPLLLADAYHARVDIPAQIASCRVGHRVRQASVLGEDIRLVSALHERLTELGVSPFDH
FT                   TLGVVVLAIGSSHPAANARTSTVASRLAEGTQWAAVTTAFITRPEASLADATDRLRRHG
FT                   ARRMVIAPWLLAPGILSDRVRGYAREAGIAMAQPLGAHPMVAATMWDRYRQAVAGRIAA
FT                   "
FT   CDS             145081..147012
FT                   /transl_table=11
FT                   /gene="ggtB"
FT                   /locus_tag="Mb2415"
FT                   /product="PROBABLE GAMMA-GLUTAMYLTRANSPEPTIDASE PRECURSOR
FT                   GGTB (GAMMA-GLUTAMYLTRANSFERASE) (GLUTAMYL TRANSPEPTIDASE)"
FT                   /EC_number="2.3.2.2"
FT                   /note="Mb2415, ggtB, len: 643 aa. Equivalent to Rv2394,
FT                   len: 643 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 643 aa overlap). Probable ggtB,
FT                   gamma-glutamyltranspeptidase precursor (EC 2.3.2.2),
FT                   similar to many e.g. Q9KVF2|VC0194 from Vibrio cholerae
FT                   (588 aa), FASTA scores: opt: 943, E(): 7.5e-47, (40.0%
FT                   identity in 597 aa overlap); O69935|SC3C8.26 from
FT                   Streptomyces coelicolor (603 aa), FASTA scores: opt: 822,
FT                   E(): 7.2e-40, (33.6% identity in 622 aa overlap);
FT                   P54422|GGT_BACSU from Bacillus subtilis (587 aa) FASTA
FT                   scores: opt: 491, E(): 8.2e-21, (33.4% identity in 574 aa
FT                   overlap); etc. Has potential signal peptide and
FT                   appropriately positioned prokaryotic lipoprotein attachment
FT                   site (PS00013)."
FT                   /db_xref="GOA:Q7TYP4"
FT                   /db_xref="InterPro:IPR000101"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP4"
FT                   /protein_id="CAD97276.1"
FT                   /translation="MSVWLRAGALVAAVMLSLSGCGGFHAGAPSTAGPCEIVPNGTPAP
FT                   KTPPATVPSSRNLATNPEIATGYRRDMTVVRTAHYAAATANPLATQVACRVLRDGGTAA
FT                   DAVVAAQAVLGLVEPQSSGIGGGGYLVYFDARTGSVQAYDGREVAPAAATENYLRWVSD
FT                   VDRSAPRPNARASGRSIGVPGILRMLEMVHNEHGRTPWRDLFGPAVTLADGGFDISARM
FT                   GAAISDAAPQLRDDPEARKYFLNPDGSPKPAGTRLTNPAYSKTLSAIASAGANAFYSGD
FT                   IAHDIVAAASDTSNGRTPGLLTIEDLAGYLAKRRQPLCTTYRGREICGMPSSGGVAVAA
FT                   TLGILEHFPMSDYAPSKVDLNGGRPTVMGVHLIAEAERLAYADRDQYIADVDFVQLPGG
FT                   SLTTLVDPGYLAARAALISPQHSMGSARPGDFGAPTAVAPPVPEHGTSHLSVVDSYGNA
FT                   ATLTTTVESSFGSYHLVDGFILNNQLSDFSAEPHATDGSPVANRVEPGKRPRSSMAPTL
FT                   VFDHSSAGRGALYAVLGSPGGSMIIQFVVKTLVAMLDWGLNPQQAVSLVDFGAANSPHT
FT                   NLGGENPEINTSDDGDHDPLVQGLRALGHRVNLAEQSSGLSAITRSEAGWAGGADPRRE
FT                   GAVMGDDA"
FT   CDS             147143..147583
FT                   /transl_table=11
FT                   /gene="Mb2416"
FT                   /locus_tag="Mb2416"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
FT                   [FIRST PART]"
FT                   /note="Mb2416, -, len: 146 aa. Equivalent to 5' end of
FT                   Rv2395, len: 667 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (100.0% identity in 44 aa overlap). Probable
FT                   conserved integral membrane protein, similar to
FT                   AAK24613|CC2646 OLIGOPEPTIDE TRANSPORTER/OPT FAMILY PROTEIN
FT                   from Caulobacter crescentus (666 aa), FASTA scores: opt:
FT                   1638, E(): 4.8e-86, (51.0% identity in 658 aa overlap);
FT                   Q9PIS5|CJ0204 PUTATIVE INTEGRAL MEMBRANE PROTEIN from
FT                   Campylobacter jejuni (665 aa), FASTA scores: opt: 1484,
FT                   E(): 2.9e-77, (40.6% identity in 658 aa overlap); and
FT                   P44016|Y561_HAEIN hypothetical integral membrane protein
FT                   from Haemophilus influenzae (635 aa), FASTA scores: opt:
FT                   1449, E(): 2.8e-75, (42.15% identity in 624 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2395 exists as a single gene.
FT                   In Mycobacterium bovis, a frameshift due to a single base
FT                   insertion (*-t) splits Rv2395 into 2 parts, Mb2416 and
FT                   Mb2417."
FT                   /db_xref="InterPro:IPR004813"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP3"
FT                   /protein_id="CAD97277.1"
FT                   /translation="MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATSH
FT                   TGRGDLDGRAAVVRQPLSGGEQYCSDDRVGGRHAVVDHLRVTGTAHDRLVERVSVLDNG
FT                   GGVCTGRDPWRHVLNSVAPRTRHRIRPAVPRRRCRSRGSQDR"
FT   CDS             147597..149147
FT                   /transl_table=11
FT                   /gene="Mb2417"
FT                   /locus_tag="Mb2417"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
FT                   [SECOND PART]"
FT                   /note="Mb2417, -, len: 516 aa. Equivalent to 3' end of
FT                   Rv2395, len: 667 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (99.8% identity in 516 aa overlap). Probable
FT                   conserved integral membrane protein, similar to
FT                   AAK24613|CC2646 OLIGOPEPTIDE TRANSPORTER/OPT FAMILY PROTEIN
FT                   from Caulobacter crescentus (666 aa), FASTA scores: opt:
FT                   1638, E(): 4.8e-86, (51.0% identity in 658 aa overlap);
FT                   Q9PIS5|CJ0204 PUTATIVE INTEGRAL MEMBRANE PROTEIN from
FT                   Campylobacter jejuni (665 aa), FASTA scores: opt: 1484,
FT                   E(): 2.9e-77, (40.6% identity in 658 aa overlap); and
FT                   P44016|Y561_HAEIN hypothetical integral membrane protein
FT                   from Haemophilus influenzae (635 aa), FASTA scores: opt:
FT                   1449, E(): 2.8e-75, (42.15% identity in 624 aa overlap).
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium
FT                   tuberculosis strain H37Rv, Rv2395 exists as a single gene.
FT                   In Mycobacterium bovis, a frameshift due to a single base
FT                   insertion (*-t) splits Rv2395 into 2 parts, Mb2416 and
FT                   Mb2417."
FT                   /db_xref="InterPro:IPR004813"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP2"
FT                   /protein_id="CAD97278.1"
FT                   /translation="MEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSGAT
FT                   MIGASLSLALIGVGHLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPDGDYAVAVARIF
FT                   STDVRFIGAGAIAVAAAWTFLKILGPILRGIADAAVSARTRRRGQAVGQTERDIPIHIV
FT                   AMVVLLSLIPIGWLLADFTDGTPLDDRRPGAIAAGVLLVLVIGLMVAAVCGYMAGLIGS
FT                   SNSPISGVGILVVVLAGLLIKTAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQD
FT                   LKTGQLVGATPWKQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQAA
FT                   LMSALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAVGMGMYLPAA
FT                   LTLMIPIGAFLGRIYDSWARWSGDDDERKKRLGVMLATGLIVGESLYGVLFAVIVATTG
FT                   KEEPLAMVGDGFRFASQPLGAIVFAGLLAWLYQRTRVTASYRLAAPAGSSKPLPDLPG"
FT   CDS             149871..150953
FT                   /transl_table=11
FT                   /gene="PE_PGRS41"
FT                   /locus_tag="Mb2418"
FT                   /product="PE-PGRS FAMILY PROTEIN"
FT                   /note="Mb2418, PE_PGRS41, len: 360 aa. Equivalent to
FT                   Rv2396, len: 361 aa, from Mycobacterium tuberculosis strain
FT                   H37Rv, (99.2% identity in 361 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PE family, PGRS subfamily of
FT                   gly-rich proteins, highly similar to many e.g.
FT                   AAK47132|MT2812 PE_PGRS family protein from Mycobacterium
FT                   tuberculosis strain CDC1551 (454 aa), FASTA scores: opt:
FT                   1256, E(): 2.4e-44, (56.0% identity in 377 aa overlap);
FT                   AAK46139|MT1866 PE_PGRS FAMILY PROTEIN from M. tuberculosis
FT                   strain CDC1551 (491 aa), FASTA scores: opt: 1250, E():
FT                   4.4e-44, (57.8% identity in 372 aa overlap);
FT                   Y278_MYCTU|Rv0278C|MTV035.06c HYPOTHETICAL PE-PGRS FAMILY
FT                   PROTEIN (957 aa), FASTA scores: opt: 1253, E(): 5.2e-44,
FT                   (55.5% identity in 400 aa overlap);
FT                   P71664|Rv1396c|MTCY21B4.13c HYPOTHETICAL GLYCINE-RICH 47.9
FT                   KDA PROTEIN (576 aa), FASTA scores: opt: 1236, E():
FT                   1.8e-43, (55.55% identity in 402 aa overlap); etc. Contains
FT                   PS00583 pfkB family of carbohydrate kinases signature 1.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 3
FT                   bp deletion (gcc-*) leads to a slightly shorter product
FT                   compared to its homolog in Mycobacterium tuberculosis
FT                   strain H37Rv (360 aa versus 361 aa)."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP1"
FT                   /protein_id="CAD97279.1"
FT                   /translation="MSFLIASPEALAATATYLTGIGSAINAANAVAAAPTTEILAAGTD
FT                   EVSTAISALFGAHAQAYQALSAHVAAFHDQFVHTLTAGAGSYMAAEAAASPLQALQLEL
FT                   LNAINAPTLALLGRPLIGDGTDAAPGSGGAGGAGGILIGNGGTGGASDLAGTGRGGVGG
FT                   AGGAGGLFGIGGAGGGCGSAVAIGGDGGAGGAGGVFSGGGAGGAGDAIGGSGGAGGTGG
FT                   LLGGGGGAGGAGGAGGNGGGASNSASIGGDGGSGGAGGMLYGAGGVGGNGGAAVAIGGD
FT                   GGAGGRAGAIGNGGDGGNGGTSNTPGGSGGDGGNGGNAGLIGSGGNGGNAEIVISGGSV
FT                   AGTGGNGGLLLGFNGTNGLP"
FT   CDS             complement(150978..152033)
FT                   /transl_table=11
FT                   /gene="cysA1"
FT                   /locus_tag="Mb2419c"
FT                   /standard_name="cysA"
FT                   /product="PROBABLE SULFATE-TRANSPORT ATP-BINDING PROTEIN
FT                   ABC TRANSPORTER CYSA1"
FT                   /note="Mb2419c, cysA1, len: 351 aa. Equivalent to Rv2397c,
FT                   len: 351 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 351 aa overlap). Probable cysA1,
FT                   sulfate-transport ATP-binding protein ABC transporter (see
FT                   citations below), similar to OTHER SULFATE ABC TRANSPORTER
FT                   ATP-BINDING PROTEINS e.g. P14788|CYSA_SYNP7 from
FT                   Synechococcus sp. (344 aa), FASTA scores: opt: 1112, E():
FT                   2.6e-56, (54.6% identity in 328 aa overlap);
FT                   P74548|CYSA_SYNY3 from Synechocystis sp. (355 aa), FASTA
FT                   scores: opt: 1063, E(): 1.7e-53, (51.9% identity in 343 aa
FT                   overlap); Q9I6L0|CYSA|PA0280 from Pseudomonas aeruginosa
FT                   (329 aa), FASTA scores: opt: 987, E(): 3.3e-49, (49.2%
FT                   identity in 339 aa overlap); etc. Also similar to many
FT                   ATP-binding proteins from Mycobacterium tuberculosis e.g.
FT                   Rv2038c, Rv1238, Rv2832c, etc. Contains PS00017
FT                   ATP/GTP-binding site motif A (P-loop), and PS00211 ABC
FT                   transporters family signature. BELONGS TO THE ATP-BINDING
FT                   TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Note that
FT                   previously known as cysA."
FT                   /db_xref="GOA:P0A4W3"
FT                   /db_xref="HSSP:1G29"
FT                   /db_xref="InterPro:IPR005116"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A4W3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97280.1"
FT                   /translation="MTYAIVVADATKRYGDFVALDHVDFVVPTGSLTALLGPSGSGKST
FT                   LLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIR
FT                   KRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFG
FT                   ALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDV
FT                   YDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRV
FT                   VVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDD
FT                   AGVERVKVTST"
FT   CDS             complement(152050..152868)
FT                   /transl_table=11
FT                   /gene="cysW"
FT                   /locus_tag="Mb2420c"
FT                   /product="PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN ABC TRANSPORTER CYSW"
FT                   /note="Mb2420c, cysW, len: 272 aa. Equivalent to Rv2398c,
FT                   len: 272 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.3% identity in 272 aa overlap). Probable cysW,
FT                   sulfate-transport integral membrane protein ABC transporter
FT                   (see citations below), similar to others e.g.
FT                   Q9K877|CYSW|BH3129 SULFATE ABC TRANSPORTER (PERMEASE) from
FT                   Bacillus halodurans (287 aa), FASTA scores: opt: 765, E():
FT                   4.1e-40, (43.8% identity in 249 aa overlap);
FT                   P27370|CYSW_SYNP7 sulfate transport system (permease)
FT                   protein from Synechococcus sp. strain PCC 7942 (Anacystis
FT                   nidulans R2) (286 aa), FASTA scores: opt: 757, E():
FT                   1.3e-39, (44.3% identity in 264 aa overlap);
FT                   Q9I6K9|CYSW|PA0281 SULFATE TRANSPORT PROTEIN from
FT                   Pseudomonas aeruginosa (289 aa), FASTA scores: opt: 753,
FT                   E(): 2.3e-39, (44.4% identity in 250 aa overlap);
FT                   P16702|P76534|CYSW_ECOLI SULFATE TRANSPORT SYSTEM PERMEASE
FT                   from Escherichia coli (291 aa), FASTA scores: opt: 633,
FT                   E(): 5.7e-32, (38.2% identity in 267 aa overlap); etc.
FT                   Contains PS00402 Binding-protein-dependent transport
FT                   systems inner membrane component signature. SIMILARITY WITH
FT                   INTEGRAL MEMBRANE COMPONENTS OF OTHER
FT                   BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEMS and BELONGS TO
FT                   THE CYSTW SUBFAMILY."
FT                   /db_xref="GOA:Q7TYP0"
FT                   /db_xref="InterPro:IPR005667"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYP0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97281.1"
FT                   /translation="MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAW
FT                   ISTPAAISALNLSLLVVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLPFAVSPV
FT                   IVGVSLILLWGSAGALGFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHELGT
FT                   DQEQAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQ
FT                   TLTLLVSDRYHRGAEYGAYALSTLLMAVSVVVLIVQMVLDAHRARAVSEG"
FT   CDS             complement(152865..153716)
FT                   /transl_table=11
FT                   /gene="cysT"
FT                   /locus_tag="Mb2421c"
FT                   /product="PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE
FT                   PROTEIN ABC TRANSPORTER CYST"
FT                   /note="Mb2421c, cysT, len: 283 aa. Equivalent to Rv2399c,
FT                   len: 283 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 283 aa overlap). Probable cysT,
FT                   sulfate-transport integral membrane protein ABC transporter
FT                   (see citations below), similar to others e.g.
FT                   BAB48989|MLR1667 PERMEASE PROTEIN OF SULFATE ABC
FT                   TRANSPORTER from Rhizobium loti (283 aa), FASTA scores:
FT                   opt: 756, E(): 7.9e-40, (40.95% identity in 271 aa
FT                   overlap); Q9K878|CYST|BH3128 SULFATE ABC TRANSPORTER
FT                   (PERMEASE) from Bacillus halodurans (279 aa), FASTA scores:
FT                   opt: 750, E(): 1.8e-39, (44.55% identity in 258 aa
FT                   overlap); P16701|CYST_ECOLI|CYSU|CYST|B2424 from
FT                   Escherichia coli (277 aa), FASTA scores: opt: 669, E():
FT                   1.9e-34, (40.0% identity in 260 aa overlap); etc. Contains
FT                   PS00402 Binding-protein-dependent transport systems inner
FT                   membrane component signature, and PS00017 ATP/GTP-binding
FT                   site motif A (P-loop). BELONGS TO THE CYSTW SUBFAMILY."
FT                   /db_xref="GOA:Q7TYN9"
FT                   /db_xref="InterPro:IPR005667"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97282.1"
FT                   /translation="MTESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLA
FT                   AIVWQAAGGGWRAFWLAVSSHAAMESFRVTLTISTAVTVINLVFGLLIAWVLVRDDFAG
FT                   KRIVDAIIDLPFALPTIVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRA
FT                   VQPVLLEIDRETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVL
FT                   IGGAVPGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEM
FT                   AA"
FT   CDS             complement(153713..154783)
FT                   /transl_table=11
FT                   /gene="subI"
FT                   /locus_tag="Mb2422c"
FT                   /product="PROBABLE SULFATE-BINDING LIPOPROTEIN SUBI"
FT                   /note="Mb2422c, subI, len: 356 aa. Equivalent to Rv2400c,
FT                   len: 356 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 356 aa overlap). Probable subI,
FT                   sulfate-binding lipoprotein component of sulfate transport
FT                   system (see citations below), equivalent to
FT                   Q9CCN3|SUBI|ML0615 (alias Q49748|B1937_F1_11, 358 aa)
FT                   PUTATIVE SULPHATE-BINDING PROTEIN from Mycobacterium leprae
FT                   (348 aa), FASTA scores: opt: 1775, E(): 2.3e-102, (76.45%
FT                   identity in 340 aa overlap). Also similar to others and
FT                   other substrate-binding proteins e.g.
FT                   P27366|SUBI_SYNP7|SBPA SULFATE-BINDING PROTEIN PRECURSOR
FT                   from Synechococcus sp. strain PCC 7942 (Anacystis nidulans
FT                   R2) (350 aa), FASTA scores: opt: 703, E(): 4.6e-36, (35.6%
FT                   identity in 351 aa overlap); Q9I6K7|SBP|PA0283
FT                   SULFATE-BINDING PROTEIN PRECURSOR from Pseudomonas
FT                   aeruginosa (332 aa), FASTA scores: opt: 591, E(): 3.7e-29,
FT                   (36.9% identity in 317 aa overlap); CAC49112|SMB21133
FT                   PUTATIVE SULFATE UPTAKE ABC TRANSPORTER PERIPLASMIC
FT                   SOLUTE-BINDING PROTEIN PRECURSOR from Rhizobium meliloti
FT                   (Sinorhizobium meliloti) (341 aa), FASTA scores: opt: 569,
FT                   E(): 8.8e-28, (36.15% identity in 321 aa overlap); etc.
FT                   BELONGS TO THE PROKARYOTIC SULFATE BINDING PROTEIN FAMILY."
FT                   /db_xref="GOA:Q7TYN8"
FT                   /db_xref="InterPro:IPR005669"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN8"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97283.1"
FT                   /translation="MLSLTLSEASCIASASRWRHIIPAGVVCALIAGIGVGCHGGPSDV
FT                   VGRAGPDRAHTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVAD
FT                   GKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDD
FT                   LLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSG
FT                   REATDVFVQGSGDVLISYENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAA
FT                   TAFRNFQYTVQAQKLWAQAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLF
FT                   DKATGSITKIYLRATG"
FT   CDS             154797..155126
FT                   /transl_table=11
FT                   /gene="Mb2423"
FT                   /locus_tag="Mb2423"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2423, -, len: 109 aa. Equivalent to Rv2401, len:
FT                   109 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 109 aa overlap). Hypothetical unknown
FT                   protein. Equivalent to AAK46768 from Mycobacterium
FT                   tuberculosis strain CDC1551 (134 aa) but shorter 25 aa.
FT                   N-terminus extended since first submission (previously 72
FT                   aa)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN7"
FT                   /protein_id="CAD97284.1"
FT                   /translation="MRDFGQRSRSGGKAIAEHCRTHELHIRPRTGGESATTVQVGRSAA
FT                   NERADIAPRKTRCCVHVAKPNRIRLADQLARSSMGEKPGHDHQRNQRDQNQRDVRPRHP
FT                   GYLGA"
FT   CDS             complement(155111..155314)
FT                   /transl_table=11
FT                   /gene="Mb2424c"
FT                   /locus_tag="Mb2424c"
FT                   /product="POSSIBLE CONSERVED MEMBRANE PROTEIN"
FT                   /note="Mb2424c, -, len: 67 aa. Equivalent to Rv2401A, len:
FT                   67 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 67 aa overlap). Possible conserved
FT                   membrane protein, highly similar, but with 29 aa shorter,
FT                   to ML0614|AL583919_34|Q49760 from Mycobacterium leprae (95
FT                   aa), FASTA scores: opt: 297, E(): 3.6e-15, (67.7% identity
FT                   in 65 aa overlap). Has hydrophobic stretch."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN6"
FT                   /protein_id="CAD97285.1"
FT                   /translation="MGPMNGFLSWWDGVELWLSGLPFALQALAVMPVVLALAYFTAALL
FT                   DALLGRVIQLIRRARRPDQAPR"
FT   CDS             155598..157526
FT                   /transl_table=11
FT                   /gene="Mb2425"
FT                   /locus_tag="Mb2425"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2425, -, len: 642 aa. Equivalent to Rv2402, len:
FT                   642 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 642 aa overlap). Conserved hypothetical
FT                   protein, highly similar to others e.g. 9X8C4|SCE36.11c
FT                   CONSERVED HYPOTHETICAL PROTEIN (FRAGMENT) from Streptomyces
FT                   coelicolor (612 aa), FASTA scores: opt: 1283, E(): 6.5e-75,
FT                   (41.9% identity in 623 aa overlap); Q9RJ38|SCI8.15
FT                   HYPOTHETICAL 66.3 KDA PROTEIN from Streptomyces coelicolor
FT                   (595 aa), FASTA scores: opt: 1152, E(): 1.7e-66, (39.9%
FT                   identity in 622 aa overlap), Q9S223|CI51.17 HYPOTHETICAL
FT                   68.4 KDA PROTEIN from Streptomyces coelicolor (612 aa),
FT                   FASTA scores: opt: 1146, E(): 4.2e-66, (40.6% identity in
FT                   623 aa overlap); YAY3_SCHPO|Q10211|c4h3.03c HYPOTHETICAL
FT                   74.5 kd PROTEIN from Schizosaccharomyces pombe (Fission
FT                   yeast) (649 aa) FASTA scores: opt: 999, E(): 1.3e-56,
FT                   (35.0% identity in 642 aa overlap); etc. Contains possible
FT                   helix-turn-helix motif, at aa 224-245 (+4.68 SD)."
FT                   /db_xref="GOA:Q7TYN5"
FT                   /db_xref="InterPro:IPR011613"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN5"
FT                   /protein_id="CAD97286.1"
FT                   /translation="MALSSSSPLRNPFPPIADYAFLSDWETTCLISPAGSVEWLCVPRP
FT                   DSPSVFGAILDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
FT                   KWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHRLGATWEYSA
FT                   EAYGEAIARANTEPDAHPTLRLTTNLRIGLEGREARARTRMKEGDDVFVALSWTKHPPP
FT                   QTYDEAADKMWQTTECWRQWINIGNFPDHPWRAYLQRSALTLKGLTYSPTGALLAASTT
FT                   SLPETPRGERNWDYRYAWIRDSTFALWGLYTLGLDREADDFFAFIADVSGANNNERHPL
FT                   QVMYGVGGERSLVEAELHHLSGYDHARPVRIGNGAYNQRQHDIWGSILDSFYLHAKSRE
FT                   QVPENLWPVLKRQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKLAERQ
FT                   GEKSYAQQWRAIADEIKADILEHGVDSRGVFTQRYGDEALDASLLLVVLTRFLPPDDPR
FT                   VRNTVLAIADELTEDGLVLRYRVHETDDGLSGEEGTFTICSFWLVSALVEIGEVGRAKR
FT                   LCERLLSFASPLLLYAEEIEPRSGRHLGNFPQAFTHLALINAVVHVIRAEEEADSSGMF
FT                   QPANAPM"
FT   CDS             complement(157604..158359)
FT                   /transl_table=11
FT                   /gene="lppR"
FT                   /locus_tag="Mb2426c"
FT                   /product="PROBABLE CONSERVED LIPOPROTEIN LPPR"
FT                   /note="Mb2426c, lppR, len: 251 aa. Equivalent to Rv2403c,
FT                   len: 251 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 251 aa overlap). Probable lppR,
FT                   conserved lipoprotein, with weak similarity with
FT                   MYCOBACTERIAL SERINE/THREONINE PROTEIN KINASES (EC 2.7.1.-)
FT                   e.g. AAK45563|MT1304 from Mycobacterium tuberculosis strain
FT                   CDC1551 (626 aa), FASTA scores: opt: 186, E(): 0.00023,
FT                   (24.4% identity in 238 aa overlap), and the C-terminal part
FT                   of Q11053|Rv1266c|MTCY50.16|PKNH_MYCTU from Mycobacterium
FT                   tuberculosis (626 aa), FASTA scores: opt: 185, E()=
FT                   0.00027, (24.35% identity in 238 aa overlap). Has signal
FT                   peptide and appropriate positioned prokaryotic lipoprotein
FT                   attachment site (PS00013). Could belong to the SER/THR
FT                   FAMILY of protein kinases."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97287.1"
FT                   /translation="MTNRWRWVVPLFAVFLAAGCTTTTTGKAGLAPNAVPRPLMGSLIQ
FT                   RVPLDGAALSTLLNQPFQALPPFPPVFGGSDSLGDSDVSARPADCVGVGYLTQRNVYRS
FT                   VEVKSVARVSWRHDGSSVKVDDLDEGVVALPSAAAADDLFARFSAQWKECDGTTLTVPA
FT                   SAFGQRSITDVRVADSVVAATVSLRRGTHSILASVPQARAVGVRGNCVVEVAVTFFGIT
FT                   HPSDQGSADISTSAVDIAHAMMDRISELS"
FT   CDS             complement(158356..160317)
FT                   /transl_table=11
FT                   /gene="lepA"
FT                   /locus_tag="Mb2427c"
FT                   /product="PROBABLE GTP-BINDING PROTEIN LEPA (GTP-BINDING
FT                   ELONGATION FACTOR)"
FT                   /note="Mb2427c, lepA, len: 653 aa. Equivalent to Rv2404c,
FT                   len: 653 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 653 aa overlap). Probable lepA,
FT                   GTP-binding protein (a protein of unknown function, but
FT                   apparently with membrane-related functions and very similar
FT                   to protein synthesis elongation factors; see citations
FT                   below). Equivalent to P53530|LEPA_MYCLE|ML0611|B1937_F3_81
FT                   GTP-BINDING PROTEIN from Mycobacterium leprae (646 aa),
FT                   FASTA scores: opt: 3610, E(): 1.2e-205, (88.0% identity in
FT                   649 aa overlap). Also highly similar to many GTP-BINDING
FT                   PROTEINS LEPA e.g. Q9RDC9|LEPA_STRCO|SCC77.29c from
FT                   Streptomyces coelicolor (622 aa), FASTA scores: opt: 3046,
FT                   E(): 2.3e-172, (74.3% identity in 626 aa overlap);
FT                   P37949|LEPA_BACSU from B. subtilis (612 aa), FASTA scores:
FT                   opt: 2430, E(): 5.3e-136, (58.7% identity in 610 aa
FT                   overlap); etc. Contains PS00017 ATP/GTP-binding site motif
FT                   A (P-loop), and PS00301 GTP-binding elongation factors
FT                   signature. BELONGS TO THE GTP-BINDING ELONGATION FACTOR
FT                   FAMILY, LEPA SUBFAMILY."
FT                   /db_xref="GOA:P65270"
FT                   /db_xref="HSSP:2EFG"
FT                   /db_xref="InterPro:IPR004161"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65270"
FT                   /protein_id="CAD97288.1"
FT                   /translation="MRTPCSQHRRDRPSAIGSQLPDADTLDTRQPPLQEIPISSFADKT
FT                   FTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKA
FT                   QNVRLPWRVDKTDYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANL
FT                   YLALDRDLHIIPVLNKIDLPAADPDRYAAEMAHIIGCEPAEVLRVSGKTGEGVSDLLDE
FT                   VVRQVPPPQGDAEAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIMMMSTGATHEL
FT                   LEVGIVSPEPKPCEGLGVGEVGYLITGVKDVRQSKVGDTVTSLSRARGAAAEALTGYRE
FT                   PKPMVYSGLYPVDGSDYPNLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHME
FT                   ITRERLEREFGLDLISTSPNVVYRVHKDDGTEIRVTNPSDWPEGKIRTVYEPVVKTTII
FT                   APSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDALKSRTRGYAS
FT                   LDYEEAGEQEAALVKVDILLQGEAVDAFSAIVHKDTAYAYGNKMTTKLKELIPRQQFEV
FT                   PVQAAIGSKIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQ
FT                   EAFVAALSTDAAGDKGKK"
FT   CDS             160338..160907
FT                   /transl_table=11
FT                   /gene="Mb2428"
FT                   /locus_tag="Mb2428"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2428, -, len: 189 aa. Equivalent to Rv2405, len:
FT                   189 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 189 aa overlap). Conserved hypothetical
FT                   protein, identical (but N-terminus longer 40 residues) to
FT                   AAK46773|MT2477 HYPOTHETICAL PROTEIN from Mycobacterium
FT                   tuberculosis strain CDC1551. Also highly similar, but
FT                   N-terminus longer 38 residues, to Q9RD03|SCCM1.41
FT                   HYPOTHETICAL 17.4 KDA PROTEIN from Streptomyces coelicolor
FT                   (154 aa), FASTA scores: opt: 451, E(): 2e-22, (48.7%
FT                   identity in 154 aa overlap). Shows also similarity with
FT                   hypothetical proteins from other species."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97289.1"
FT                   /translation="MQRFAENLVFTEAPKLVRHLQNTQETLRTIRQAVKITANIMTTAV
FT                   PSPPAEIAAGRPVTSTSCPTAARARRLVYAPDLDGRADPGEIVWTWVAYEQDPTRGKDR
FT                   PVLVVGRDRSVLLGLLVSSQERHAADRDWVGIGSGAWDYEGRESWVRLDRVLDVPEESI
FT                   RREGAILEREVFDVVAARLRADYAWR"
FT   CDS             complement(161078..161506)
FT                   /transl_table=11
FT                   /gene="Mb2429c"
FT                   /locus_tag="Mb2429c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2429c, -, len: 142 aa. Equivalent to Rv2406c, len:
FT                   142 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 142 aa overlap). Conserved hypothetical
FT                   protein. C-terminal region is identical with many CBS
FT                   DOMAIN PROTEIN e.g. AAK46774|MT2478 CBS DOMAIN PROTEIN from
FT                   Mycobacterium tuberculosis strain CDC1551 (aa 47-142),
FT                   FASTA scores: opt: 594, E(): 1.9e-30, (98.97% identity in
FT                   97 aa overlap); etc. Also similar to other hypothetical
FT                   proteins e.g. AAK24594|CC2626 CBS DOMAIN PROTEIN from
FT                   Caulobacter crescentus (157 aa), FASTA scores: opt: 377,
FT                   E(): 8.3e-17, (42.55% identity in 141 aa overlap);
FT                   BAB47826|MLR0188 from Rhizobium loti; etc."
FT                   /db_xref="InterPro:IPR000644"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN2"
FT                   /protein_id="CAD97290.1"
FT                   /translation="MRIADVLRNKGAAVVTINPDATVGELLAGLAEQNIGAMVVVGAEG
FT                   VVGIVSERDVVRQLHTYGASVLSRPVAKIMSTTVATCTKSDTVDKISVLMTENRVRHVP
FT                   VLDGKKLIGIVSIGDVVKSRMGELEAEQQQLQSYITQG"
FT   CDS             161766..162608
FT                   /transl_table=11
FT                   /gene="Mb2430"
FT                   /locus_tag="Mb2430"
FT                   /product="CONSERVED HYPOTHETCAL PROTEIN"
FT                   /note="Mb2430, -, len: 280 aa. Equivalent to Rv2407, len:
FT                   273 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (97.5% identity in 280 aa overlap). Conserved hypothetical
FT                   protein, highly similar (but longer at N-terminus) to
FT                   AAK46775|MT2479 putative arylsulfatase from Mycobacterium
FT                   tuberculosis strain CDC1551 (224 aa) FASTA scores: opt:
FT                   1433, E(): 2.5e-81, (96.43% identity in 224 aa overlap);
FT                   O33130|MLCL536.01 HYPOTHETICAL PROTEIN from Mycobacterium
FT                   leprae (220 aa), FASTA scores: opt: 658, E(): 1.5e-33,
FT                   (56.75% identity in 215 aa overlap). Also similar to
FT                   AAK23160|CC1176 Metallo-beta-lactamase family protein from
FT                   Caulobacter crescentus (317 aa), FASTA scores: opt: 286,
FT                   E(): 1.8e-10, (33% identity in 291 aa overlap). And similar
FT                   to other hypothetical proteins eg Q49744|B1937_C1_163
FT                   HYPOTHETICAL 22.6 KDA PROTEIN (PRECURSOR) from
FT                   Mycobacterium leprae (211 aa), FASTA scores: opt: 623, E():
FT                   2.1e-31, (56.3% identity in 206 aa overlap); O27859|MTH1831
FT                   CONSERVED PROTEIN from Methanothermobacter
FT                   thermautotrophicus (307 aa), FASTA scores: opt: 268, E():
FT                   2.3e-09, (28.35% identity in 307 aa overlap); etc.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 21
FT                   bp in-frame insertion leads to a longer product compared to
FT                   its homolog in Mycobacterium tuberculosis strain H37Rv (280
FT                   aa versus 273 aa)."
FT                   /db_xref="GOA:Q7TYN1"
FT                   /db_xref="InterPro:IPR001279"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYN1"
FT                   /protein_id="CAD97291.1"
FT                   /translation="MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAA
FT                   AVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEAT
FT                   LKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFR
FT                   IESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQ
FT                   EAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR"
FT   CDS             163201..163920
FT                   /transl_table=11
FT                   /gene="PE24"
FT                   /locus_tag="Mb2431"
FT                   /product="POSSIBLE PE FAMILY-RELATED PROTEIN"
FT                   /note="Mb2431, PE24, len: 239 aa. Equivalent to Rv2408,
FT                   len: 239 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 239 aa overlap). Possibly a member of
FT                   PE family, similar to AAK46440|MT2159 from Mycobacterium
FT                   tuberculosis strain CDC1551 (491 aa) FASTA scores: opt:
FT                   269, E(): 5.4e-08, (38.45% identity in 156 aa overlap) and
FT                   AAK45466|MT1209 from Mycobacterium tuberculosis strain
FT                   CDC1551 (308 aa), FASTA scores: opt: 265, E(): 6.3e-08,
FT                   (36.0% identity in 197 aa overlap)."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYN0"
FT                   /protein_id="CAD97292.1"
FT                   /translation="MLIARPDILCSRGPEAMRAKAADLDLAAAAKTVGVQPAADQVAAA
FT                   IAAILLSHAQIYQDISTQMAAFHDQLVENRTADSTSYASAEANAQQSLLNAMDAPSWQQ
FT                   RRETVGEVGLPADPAGSGTATAAVAAATTARAGSRSAAQATVAPIGGLKLRRESALSQP
FT                   GDLHHHVEVGDALPRVDPFQRGNVGVVAAYTHTDVLLGDLIVIGGVVVPPSTGPGLNPG
FT                   MAAPVYRLSHHGITLRV"
FT   CDS             complement(163678..164517)
FT                   /transl_table=11
FT                   /gene="Mb2432c"
FT                   /locus_tag="Mb2432c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2432c, -, len: 279 aa. Equivalent to Rv2409c, len:
FT                   279 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 279 aa overlap). Conserved hypothetical
FT                   protein, equivalent to
FT                   Q49757|YP69_MYCLE|G466976|B1937_F2_39 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (279 aa), FASTA scores: opt:
FT                   1564, E(): 4.6e-95, (82.1% identity in 279 aa overlap).
FT                   Also similar to others e.g. Q9RSX6|DR1993 from Deinococcus
FT                   radiodurans (274 aa), FASTA scores: opt: 494, E(): 4e-25,
FT                   (35.1% identity in 282 aa overlap); BAB49898|Mll2875 from
FT                   Rhizobium loti (Mesorhizobium loti) (294 aa), FASTA scores:
FT                   opt: 382, E(): 8.9e-18, (29.75% identity in 269 aa
FT                   overlap); Q9I305|PA1732 from Pseudomonas aeruginosa (266
FT                   aa), FASTA scores: opt: 326, E(): 3.7e-14, (31.25% identity
FT                   in 275 aa overlap); etc. Also similar to Rv2569c|MTCY227.32
FT                   from Mycobacterium tuberculosis."
FT                   /db_xref="InterPro:IPR002931"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM9"
FT                   /protein_id="CAD97293.1"
FT                   /translation="MWRTRVVHTTGYVYQSPVTASYNEARLTPRSSSRQNLVLNRVETI
FT                   PATRSYRYIDYWGTAVTAFDLHAPHTELTVTSSSVVETERPEPLAAKATWADLQSTAVI
FT                   DRFDEVLRPTPHTPASARVDAVGRRIRKCHEPSEAVVAAARWARSELDYIPGTTSVHSS
FT                   GLDALEQGKGVCQDFVHLSLMVLRSMGIPCRYVSGYLHPKRDAVVGKTVDGRSHAWVQA
FT                   WTGGWWHYDPTNDNEITEQYISVGVGRDYTDVSPLKGIYSGEGVTDLDVVVEITRLA"
FT   CDS             complement(164517..165494)
FT                   /transl_table=11
FT                   /gene="Mb2433c"
FT                   /locus_tag="Mb2433c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2433c, -, len: 325 aa. Equivalent to Rv2410c, len:
FT                   325 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 325 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q49770|CAC30114|ML0606 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Mycobacterium leprae (325 aa),
FT                   FASTA scores: opt: 1928, E(): 3.5e-117, (90.75% identity in
FT                   325 aa overlap). Also some similarity with other
FT                   hypothetical proteins e.g. Q9RST2|DR2041 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Deinococcus radiodurans (316 aa),
FT                   FASTA scores: opt: 329, E(): 5.3e-14, (32.4% identity in
FT                   318 aa overlap); C-terminus of Q9HUN7|PA4927 HYPOTHETICAL
FT                   PROTEIN from Pseudomonas aeruginosa (830 aa), FASTA scores:
FT                   opt: 297, E(): 1.5e-11, (27.6% identity in 315 aa overlap);
FT                   etc."
FT                   /db_xref="InterPro:IPR007296"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM8"
FT                   /protein_id="CAD97294.1"
FT                   /translation="MLARNAEALYWIGRYVERADDTARILDVAVHQLLEDSSVDPDQAS
FT                   RLLLRVLGIEPPDHELDVWSLTDLVAFSTNSQGGSSIVDAISAARENAKSAREVTSSET
FT                   WECLNTTYNALPERERAAKRLGPHEFLSFIEGRAAMFAGLADSTLLRDDGYRFMLLGRA
FT                   IERVDMTVRLLLSRVGDSASSPAWVTLLRSAGAHDTYLRTYRGVLDAGRVVEFMMLDRL
FT                   FPRSVFHSLKLAEHNLAELMHNPHSRIGATTEAQRLLGQARSELEFVQPGVLLETLESR
FT                   LAGLQTTCRDVGDALALQYFHAAPWVAWSDAGQRGQLVGSQEES"
FT   CDS             complement(165494..167149)
FT                   /transl_table=11
FT                   /gene="Mb2434c"
FT                   /locus_tag="Mb2434c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2434c, -, len: 551 aa. Equivalent to Rv2411c, len:
FT                   551 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 551 aa overlap). Hypothetical protein,
FT                   highly similar to
FT                   Q49755|YO11_MYCLE|ML0605|MLCL536.05c|U1937B|B1937_F1_4
FT                   HYPOTHETICAL 61.8 KDA PROTEIN from Mycobacterium leprae
FT                   (561 aa), FASTA scores, opt: 3163, E(): 4.1e-178, (87.35%
FT                   identity in 554 aa overlap). Also highly similar, except in
FT                   N-terminus, to others e.g. Q55587|Y335_SYNY3|SLL0335
FT                   HYPOTHETICAL PROTEIN from Synechocystis sp. strain PCC 6803
FT                   (481 aa), FASTA scores: opt: 1620, E(): 1.2e-87, (52.8%
FT                   identity in 468 aa overlap); Q9I307|PA1730 HYPOTHETICAL
FT                   PROTEIN from Pseudomonas aeruginosa (470 aa), FASTA scores:
FT                   opt: 1574, E(): 5.8e-85, (52.7% identity in 467 aa
FT                   overlap); Q9RST1|DR2042 CONSERVED HYPOTHETICAL PROTEIN from
FT                   Deinococcus radiodurans (655 aa), FASTA scores: opt: 1561,
FT                   E(): 4.4e-84, (53.3% identity in 467 aa overlap); etc."
FT                   /db_xref="InterPro:IPR016450"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65002"
FT                   /protein_id="CAD97295.1"
FT                   /translation="MRRVSLPNQLNETRRRSPTRGERIFGGYNTSDVYAMAFDEMFDAQ
FT                   GIVRGPYKGIYAELAPSDASELKARADALGRAFIDQGITFSLSGQERPFPLDLVPRVIS
FT                   APEWTRLERGITQRVKALECYLDDIYGDQEILRDGVIPRRLVTSCEHFHRQAVGIVPPN
FT                   GVRIHVAGIDLIRDHRGDFRVLEDNLRSPSGVSYVMENRRTMARVFPNLFATHRVRAVD
FT                   DYASHLLRALRNSAATNEADPTVVVLTPGVYNSAYFEHSLLARQMGVELVEGRDLFCRD
FT                   NQVYMRTTEGERQVDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGNVVLSSAIGN
FT                   GVGDDKLVYTYVPTMIEYYLHEKPLLANVETLRCWLDDEREEVLDRIRELVLKPVEGSG
FT                   GYGIVFGPEASQAELAAVSQKIRDDPRSWIAQPMMELSTVPTRIEGTLAPRYVDLRPFA
FT                   VNDGNEVWVLPGGLTRVALVEGSRVVNSSQGGGSKDTWVLAPRASAAARELGAAQIVRS
FT                   LPQPLCDPTVDASGYEPHDQQPQQQQQQQQQAFH"
FT   CDS             167259..167519
FT                   /transl_table=11
FT                   /gene="rpsT"
FT                   /locus_tag="Mb2435"
FT                   /product="PROBABLE 30S RIBOSOMAL PROTEIN S20 RPST"
FT                   /note="Mb2435, rpsT, len: 86 aa. Equivalent to Rv2412, len:
FT                   86 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 86 aa overlap). Probable rpsT, 30s
FT                   ribosomal protein s20, equivalent to
FT                   O33132|RS20_MYCLE|L0604|MLCL536.06 30S RIBOSOMAL PROTEIN
FT                   S20 from Mycobacterium leprae (86 aa), FASTA scores: opt:
FT                   456, E(): 4.6e-24, (87.20% identity in 86 aa overlap). Also
FT                   highly similar or similar to others e.g.
FT                   Q9RDM3|RPST|SCC123.01 30S RIBOSOMAL PROTEIN S20 from
FT                   Streptomyces coelicolor (88 aa), FASTA scores: opt: 363,
FT                   E(): 7.1e-18, (70.95% identity in 86 aa overlap);
FT                   Q9KD79|RPST|BH1339 RIBOSOMAL PROTEIN S20 (BS20) from
FT                   Bacillus halodurans (91 aa), FASTA scores: opt: 252, E():
FT                   1.8e-10, (49.4% identity in 85 aa overlap);
FT                   P02378|RS20_ECOLI 30s ribosomal protein s20 from
FT                   Escherichia coli (86 aa), FASTA scores: opt: 210, E():
FT                   1e-07, (42.4% identity in 85 aa overlap); etc. BELONGS TO
FT                   THE S20P FAMILY OF RIBOSOMAL PROTEINS."
FT                   /db_xref="GOA:P66506"
FT                   /db_xref="InterPro:IPR002583"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66506"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97296.1"
FT                   /translation="MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKA
FT                   KAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL"
FT   CDS             complement(167535..168485)
FT                   /transl_table=11
FT                   /gene="Mb2436c"
FT                   /locus_tag="Mb2436c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2436c, -, len: 316 aa. Equivalent to Rv2413c, len:
FT                   316 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 316 aa overlap). Conserved hypothetical
FT                   protein, highly similar to
FT                   O33133|MLCL536.07c|ML0603|Q49756|G466975|B1937_F2_36
FT                   hypothetical 39.1 KDA protein from Mycobacterium leprae
FT                   (389 aa), FASTA scores: opt: 1683, E(): 1.8e-88, (83.9%
FT                   identity in 316 aa overlap). ML0603 is a putative
FT                   lipoprotein with an N-terminal signal sequence and
FT                   appropriately positioned prokaryotic lipoprotein lipid
FT                   attachment site that is not present in Rv2413c as this
FT                   seems to be 73 aa shorter. Also some similarity with
FT                   various proteins from other organisms e.g.
FT                   Q9RDM2|SCC123.02c PUTATIVE DNA-BINDING PROTEIN from
FT                   Streptomyces coelicolor (336 aa), FASTA scores: opt: 792,
FT                   E(): 6.1e-38, (42.4% identity in 316 aa overlap);
FT                   Q9HX31|HOLA|PA3989 DNA POLYMERASE III, DELTA SUBUNIT from
FT                   Pseudomonas aeruginosa (345 aa), FASTA scores: opt: 173,
FT                   E(): 0.0084, (25.4% identity in 307 aa overlap); etc."
FT                   /db_xref="GOA:Q7TYM7"
FT                   /db_xref="InterPro:IPR010372"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM7"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97297.1"
FT                   /translation="MHLVLGDEELLVERAVADVLRSARQRAGTADVPVSRMRAGDVGAY
FT                   ELAELLSPSLFAEERIVVLGAAAEAGKDAAAVIESAAADLPAGTVLVVVHSGGGRAKSL
FT                   ANQLRSMGAQVHPCARITKVSERADFIRSEFASLRVKVDDETVTALLDAVGSDVRELAS
FT                   ACSQLVADTGGAVDAAAVRRYHSGKAEVRGFDIADKAVAGDVAGAAEALRWAMMRGEPL
FT                   VVLADALAEAVHTIGRVGPQSGDPYRLAAQLGMPPWRVQKAQKQARRWSRDTVATAMRL
FT                   VAELNANVKGAVADADYALESAVRQVAELVADRGR"
FT   CDS             complement(168490..170061)
FT                   /transl_table=11
FT                   /gene="Mb2437c"
FT                   /locus_tag="Mb2437c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2437c, -, len: 523 aa. Similar to Rv2414c, len:
FT                   514 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 483 aa overlap). Conserved hypothetical
FT                   protein, showing some similarity with COME OPERON PROTEINS
FT                   3 (COMEC OR COME3) e.g. Q9RTB1|DR1854 PUTATIVE COMPETENCE
FT                   PROTEIN COMEC/REC2 from Deinococcus radiodurans (755 aa),
FT                   FASTA scores: opt: 311, E(): 8.2e-11, (27.3% identity in
FT                   538 aa overlap); P73100|COME|SLL1929 COME PROTEIN from
FT                   Synechocystis sp. strain PCC 6803 (709 aa), FASTA scores:
FT                   opt: 302, E(): 2.6e-10, (26.3% identity in 323 aa overlap)
FT                   (no similarity on N-terminus); P39695|CME3_BACSU COME
FT                   OPERON PROTEIN 3 from Bacillus subtilis (776 aa), FASTA
FT                   scores: opt: 273, E(): 1.4e-08, (25.2% identity in 282 aa
FT                   overlap) (no similarity on N-terminus); etc.
FT                   REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
FT                   single base insertion (*-t) leads to a longer product with
FT                   a different COOH part compared to its homolog in
FT                   Mycobacterium tuberculosis H37Rv (523 aa versus 514 aa)."
FT                   /db_xref="InterPro:IPR004477"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM6"
FT                   /protein_id="CAD97298.1"
FT                   /translation="MGFGASRLDVRLVPAALVSWIVTAAGIVWPIGNVCALCCVVVALG
FT                   GGALWWCVARRSWHAPRLGSISAGLVAVGMVGAGYGLAVALRSEAVDRHPITVAFGTSA
FT                   LVTVTPSESPVSLGRGRLMFRATVQRLRDDETSGRVVVFARALDFGELMVGQPVQFRAR
FT                   ISRPARHDLTVAVFNATGRPTVGRAGPVHRAAHIVRHRFAAAVREVLPADQATMLPALV
FT                   LGDTSTVTALTSREFRAAGLTHLTAVSGANVTIVCAAALVSARLIGPRAAVVCAAVALV
FT                   AFVILVQPTASVLRAAVMGAIALVGMLSARRRQAIPALSGSVLVLLAAAPHLAVDIGFA
FT                   LSVAATGALVVIAPVWSRRLVDRGCPKVLADALAVAAAAQLVTAPLVAAISGRVSLVAV
FT                   VANLAVAAVIAPITVLGSVAAVLVVPWPAGAQVLIRFTGPEVWWVLRVAHWASGVPAAT
FT                   VPVAAGLPGVLLVGGATVFTVAQWRLALVSRGHVQNDGGGRHMSACLVAVRAGRPFVTP
FT                   SWGERG"
FT   CDS             complement(170076..170969)
FT                   /transl_table=11
FT                   /gene="Mb2438c"
FT                   /locus_tag="Mb2438c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2438c, -, len: 297 aa. Equivalent to Rv2415c, len:
FT                   297 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 297 aa overlap). Hypothetical protein,
FT                   with some similarity in C-terminal part to comE operon
FT                   proteins 1 e.g. Q9EU10|COME|COME4|COME1|COME2|COME3 COME
FT                   PROTEIN (a competence protein with DNA-binding activity)
FT                   from Neisseria gonorrhoeae (99 aa), FASTA scores: opt: 190,
FT                   E(): 0.0032, (49.2% identity in 61 aa overlap);
FT                   Q9JYB8|NMB1657 from Neisseria meningitidis (205 aa) FASTA
FT                   scores: opt: 191, E(): 0.0052, (49.2% identity in 61 aa
FT                   overlap); CME1_BACSU|P39694 come operon protein 1 from
FT                   Bacillus subtilis (205 aa), FASTA scores, opt: 181, E():
FT                   0.017 (29.8% identity in 218 aa overlap); etc."
FT                   /db_xref="GOA:Q7TYM5"
FT                   /db_xref="InterPro:IPR019554"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM5"
FT                   /protein_id="CAD97299.1"
FT                   /translation="MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDE
FT                   PRDDPNSLLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTE
FT                   PVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADA
FT                   LQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGT
FT                   ATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVD
FT                   GIGPARLDKLRNLVRV"
FT   CDS             complement(171309..172535)
FT                   /transl_table=11
FT                   /gene="Mb2439c"
FT                   /locus_tag="Mb2439c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2439c, -, len: 408 aa. Equivalent to Rv2416c, len:
FT                   408 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 408 aa overlap). Conserved hypothetical
FT                   protein, sharing similarity with Q9F309|SCC80.10
FT                   HYPOTHETICAL 44.7 KDA PROTEIN from Streptomyces coelicolor
FT                   (413 aa), FASTA scores: opt: 382, E(): 1e-16, (31.45%
FT                   identity in 407 aa overlap); Q9K4F4|SCD66.23 CONSERVED
FT                   HYPOTHETICAL PROTEIN from Streptomyces coelicolor (418 aa),
FT                   FASTA scores: opt: 238, E(): 1.3e-07, (36.5% identity in
FT                   364 aa overlap): and Q54238|G1139577|ORF5 hypothetical
FT                   protein from Streptomyces griseus (416 aa), FASTA scores:
FT                   opt: 237, E(): 1.5e-07, (34.0 identity in 423 aa overlap)."
FT                   /db_xref="GOA:P59772"
FT                   /db_xref="InterPro:IPR000182"
FT                   /db_xref="UniProtKB/Swiss-Prot:P59772"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97300.1"
FT                   /translation="MPQSDSVTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTL
FT                   VPTDGAVVVRDGAGPGSEVVGMALYMDLRLAVPGEVVLPTAGLSFVAVAPTHRRRGLLR
FT                   AMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGG
FT                   LGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFA
FT                   LLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPL
FT                   PHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIG
FT                   DGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASD
FT                   VPVQTAFEF"
FT   CDS             complement(172657..173499)
FT                   /transl_table=11
FT                   /gene="Mb2440c"
FT                   /locus_tag="Mb2440c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2440c, -, len: 280 aa. Equivalent to Rv2417c, len:
FT                   280 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 280 aa overlap). Conserved hypothetical
FT                   protein, highly similar to Q9RDL7|SCC123.07c HYPOTHETICAL
FT                   29.2 KDA PROTEIN from Streptomyces coelicolor (281 aa),
FT                   FASTA scores: opt: 579, E(): 3.6e-27, (38.3% identity in
FT                   274 aa overlap). Also some similarity with DEGV proteins or
FT                   hypothetical proteins from other organisms, e.g.
FT                   Q9RSY3|DR1986 from Deinococcus radiodurans (281 aa), FASTA
FT                   scores: opt: 393, E(): 3.4e-16, (31.0% identity in 280 aa
FT                   overlap); P32436|DEGV_BACSU from Bacillus subtilis (281
FT                   aa), FASTA scores: opt: 365, E(): 1.5e-14, (27.8% identity
FT                   in 284 aa overlap); BAB41937|BAB46307|SA0704|SAV0749
FT                   Conserved hypothetical protein from Staphylococcus aureus
FT                   strain Mu50 and N315 (288 aa), FASTA scores: opt: 371, E():
FT                   7e-15, (28.85% identity in 281 aa overlap); etc."
FT                   /db_xref="InterPro:IPR003797"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67369"
FT                   /protein_id="CAD97301.1"
FT                   /translation="MTVVVVTDTSCRLPADLREQWSIRQVPLHILLDGLDLRDGVDEIP
FT                   DDIHKRHATTAGATPVELSAAYQRALADSGGDGVVAVHISSALSGTFRAAELTAAELGP
FT                   AVRVIDSRSAAMGVGFAALAAGRAAAAGDELDTVARAAAAAVSRIHAFVAVARLDNLRR
FT                   SGRISGAKAWLGTALALKPLLSVDDGKLVLVQRVRTVSNATAVMIDRVCQLVGDRPAAL
FT                   AVHHVADPAAANDVAAALAERLPACEPAMVTAMGPVLALHVGAGAVGVCVDVGASPPA"
FT   CDS             complement(173580..174323)
FT                   /transl_table=11
FT                   /gene="Mb2441c"
FT                   /locus_tag="Mb2441c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2441c, -, len: 247 aa. Equivalent to Rv2418c, len:
FT                   247 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 247 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM4"
FT                   /protein_id="CAD97302.1"
FT                   /translation="MSSRRGRRPALLVFADSLAYYGPTGGLPADDPRIWPNIVASQLDW
FT                   DLELIGRIGWTCRDVWWAATQDPRAWAALPRAGAVIFATGGMDSLPSVLPTALRELIRY
FT                   VRPSWLRRWVRDGYAWVQPRLSPVARAALPPHLTAEYLEKTRGAIDFNRPGIPIIASLP
FT                   SVHIAETYGKAHHGRAGTVAAITEWAQHHDIPLVDLKAAVAEQILSGYGNRDGIHWNFE
FT                   AHQAVAELMLKALAEAGVPNEKSRG"
FT   CDS             complement(174313..174984)
FT                   /transl_table=11
FT                   /gene="Mb2442c"
FT                   /locus_tag="Mb2442c"
FT                   /product="PROBABLE PHOSPHOGLYCERATE MUTASE
FT                   (PHOSPHOGLYCEROMUTASE)"
FT                   /EC_number="5.4.2.1"
FT                   /note="Mb2442c, -, len: 223 aa. Equivalent to Rv2419c, len:
FT                   223 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.6% identity in 223 aa overlap). Probable
FT                   phosphoglycerate mutase (EC 5.4.2.1), equivalent to
FT                   Q9CC00|ML1452 POSSIBLE PHOSPHOGLYCERATE MUTASE from
FT                   Mycobacterium leprae (224 aa), FASTA scores: opt: 1206,
FT                   E(): 8.8e-68, (80.35% identity in 224 aa overlap). Also
FT                   highly similar to Q9RDL0|SCC123.14c PUTATIVE
FT                   PHOSPHOGLYCERATE MUTASE from Streptomyces coelicolor (223
FT                   aa), FASTA scores: opt: 431, E(): 9.4e-20, (40.85% identity
FT                   in 213 aa overlap); and similar to others e.g.
FT                   Q9RVD2|DR1097 from Deinococcus radiodurans (232 aa), FASTA
FT                   scores: opt: 291, E(): 4.6e-11, (39.3% identity in 173 aa
FT                   overlap); etc. Some similarity to
FT                   Q10512|Rv2228c|Y019_MYCTU|MT2287|MTcy427.09c hypothetical
FT                   39.2 kd protein from Mycobacterium tuberculosis (364 aa)
FT                   FASTA scores: opt: 196, E(): 2.8e-06, (45.6% identity in 79
FT                   aa overlap). Contains PS00175 Phosphoglycerate mutase
FT                   family phosphohistidine signature. BELONGS TO THE
FT                   PHOSPHOGLYCERATE MUTASE FAMILY."
FT                   /db_xref="GOA:Q7TYM3"
FT                   /db_xref="HSSP:1EBB"
FT                   /db_xref="InterPro:IPR013078"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM3"
FT                   /protein_id="CAD97303.1"
FT                   /translation="MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVL
FT                   GKRQPLLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPG
FT                   ARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWGGADEPDRPVVLVAHGGLI
FT                   AVLSAALLKLPVANWPALGGMGNASWTQLSGHWAPGSDFESIRWRLDVWNASAQVSSDV
FT                   L"
FT   CDS             complement(174981..175361)
FT                   /transl_table=11
FT                   /gene="Mb2443c"
FT                   /locus_tag="Mb2443c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2443c, -, len: 126 aa. Equivalent to Rv2420c, len:
FT                   126 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 126 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBZ9|ML1453 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (129 aa), FASTA scores: opt: 681,
FT                   E(): 1.6e-38, (87.0% identity in 123 aa overlap). Also
FT                   highly similar to Q9RDK9|SCC123.15c HYPOTHETICAL PROTEIN
FT                   from Streptomyces coelicolor (148 aa), FASTA scores: opt:
FT                   447, E(): 5.8e-23, (52.7% identity in 129 aa overlap); and
FT                   similar to others e.g. P54457|YQEL_BACSU HYPOTHETICAL
FT                   PROTEIN from Bacillus subtilis (118 aa), FASTA scores: opt:
FT                   318, E(): 1.8e-14, (37.3% identity in 110 aa overlap);
FT                   Q9KD89|BH1328 HYPOTHETICAL PROTEIN from Bacillus halodurans
FT                   (117 aa), FASTA scores: opt: 296, E(): 5.1e-13, (37.6%
FT                   identity in 109 aa overlap); etc."
FT                   /db_xref="InterPro:IPR004394"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM2"
FT                   /protein_id="CAD97304.1"
FT                   /translation="MTANREAIDMARVAAGAAAAKLADDVVVIDVSGQLVITDCFVIAS
FT                   GSNERQVNAIVDEVEEKMRQAGYRPARREGAREGRWTLLDYRDIVVHIQHQDDRNFYAL
FT                   DRLWGDCPVVPVDLSANSAGAQ"
FT   CDS             complement(175358..175993)
FT                   /transl_table=11
FT                   /gene="nadD"
FT                   /locus_tag="Mb2444c"
FT                   /product="PROBABLE NICOTINATE-NUCLEOTIDE
FT                   ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE)
FT                   (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NICOTINATE MONONUCLEOTIDE
FT                   ADENYLYLTRANSFERASE) (NAMN ADENYLYLTRANSFERASE)"
FT                   /EC_number="2.7.7.18"
FT                   /note="Mb2444c, nadD, len: 211 aa. Equivalent to Rv2421c,
FT                   len: 211 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.5% identity in 211 aa overlap). Probable nadD,
FT                   nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18),
FT                   equivalent to Q9CBZ8|NADD_MYCLE|ML1454 PROBABLE
FT                   NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE from
FT                   Mycobacterium leprae (214 aa), FASTA scores: opt: 1125,
FT                   E(): 2.7e-66, (80.2% identity in 212 aa overlap). Also
FT                   highly similar to Q9RDK7|NADD_STRCO PROBABLE
FT                   NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE from Streptomyces
FT                   coelicolor (188 aa), FASTA scores: opt: 855, E(): 9.8e-49,
FT                   (66.5% identity in 194 aa overlap); and similar to others
FT                   e.g. P54455|NADD_BACSU from Bacillus subtilis (189 aa),
FT                   FASTA scores: opt: 351, E(): 7e-16, (36.1% identity in 191
FT                   aa overlap); etc. BELONGS TO THE NADD FAMILY."
FT                   /db_xref="GOA:Q7TYM1"
FT                   /db_xref="HSSP:1KAM"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYM1"
FT                   /protein_id="CAD97305.1"
FT                   /translation="MGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSA
FT                   AEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALA
FT                   SIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDC
FT                   RQRAEQSRPLWYLMPDSVVQYVSKCRLYCGACDAGARSTTSLAAGNGL"
FT   CDS             176268..176540
FT                   /transl_table=11
FT                   /gene="Mb2445"
FT                   /locus_tag="Mb2445"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2445, -, len: 90 aa. Equivalent to Rv2422, len: 90
FT                   aa, from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 90 aa overlap). Hypothetical unknown protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYM0"
FT                   /protein_id="CAD97306.1"
FT                   /translation="MPASVSTVLVDTSVAVAPVVADHDHHEDTFQALRGRTLGLAGHAA
FT                   FERRTLATVAKLLAHTFPATRFLGAGAAMSLLPELAPAEIAGGAV"
FT   CDS             176782..177828
FT                   /transl_table=11
FT                   /gene="Mb2446"
FT                   /locus_tag="Mb2446"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2446, -, len: 348 aa. Equivalent to Rv2423, len:
FT                   348 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 348 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL9"
FT                   /protein_id="CAD97307.1"
FT                   /translation="MDNLPIESAESTRLAKAAMTRRFYTRSVVKGEITLPAVPSMIDEY
FT                   VTMCAGLFAGVGRKFSDEELAHLRAVLQGQLAEAYAASQRSTIVISYNAPMGPTLHYQV
FT                   RAQWRTVAQEYENWIATREPPLFGTEPDARVWALANEAADPTTHRVLEIGAGTGRNALA
FT                   LARRGHPVDVVEMTPKFADIIRSDAERDSLDVRVIMRDVFSTMDDLRQDYQLMVLSEVV
FT                   PDFRTTQQLRNLFELAAQCLAPGARLVFNAFLANGDYAPDQAAREFGQQMYTGMCTRAE
FT                   MSAAAAGLPLELVADDSVYDYEKTHLPPGAWPPTSWYADWIRGLDVFTTNVESCPIEMR
FT                   WLVFQRRR"
FT   repeat_region   177829..177841
FT                   /rpt_type=INVERTED
FT                   /note="13 bp imperfect inverted repeat, IRR, GCAGTCGTAAAAG,
FT                   flanking IS element IS1558."
FT   repeat_region   complement(177829..179039)
FT                   /mobile_element="insertion sequence:IS1558"
FT                   /locus_tag="IS1558-2"
FT                   /note="IS1558-2, len: 1211 nt. Equivalent to IS1558, len:
FT                   999 nt, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.4% identity in 999 nt overlap)."
FT   CDS             complement(177961..178653)
FT                   /transl_table=11
FT                   /gene="Mb2447c"
FT                   /locus_tag="Mb2447c"
FT                   /product="PROBABLE TRANSPOSASE [SECOND PART]"
FT                   /note="Mb2447c, -, len: 230 aa. Equivalent to 3' end of
FT                   Rv2424c, len: 333 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (98.7% identity in 230 aa overlap). Probable
FT                   transposase for IS1558, similar to IS element proteins e.g.
FT                   AL021957|Rv2177c|MTV021_10 from Mycobacterium tuberculosis
FT                   (221 aa), FASTA scores: opt: 1491, E(): 6.2e-87, (98.6%
FT                   identity in 221 aa overlap); P19780|YIS1_STRCO HYPOTHETICAL
FT                   INSERTION ELEMENT IS110 from Streptomyces coelicolor (45
FT                   aa), FASTA scores: opt: 203, E(): 1.7e-05; (27.3% identity
FT                   in 238 aa overlap); etc. Contains PS01159 WW/rsp5/WWP
FT                   domain signature. REMARK-M.bovis-M.tuberculosis: In
FT                   Mycobacterium tuberculosis strain H37Rv, Rv2424c exists as
FT                   a single gene. In Mycobacterium bovis, a frameshift due to
FT                   a 2 bp deletion (gt-*) splits Rv2424c into 2 parts, Mb2447c
FT                   and Mb2448c."
FT                   /db_xref="GOA:Q7TYL8"
FT                   /db_xref="InterPro:IPR003346"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL8"
FT                   /protein_id="CAD97308.1"
FT                   /translation="MLADLARGSMRSKIPDLQRALEGRFDDHHALMCRLHLAHLDQLDA
FT                   MIGALDEQIEQLMHPFCARRELIASIPGIGVGASATVISEIGADPAAWFPSAEHLASWV
FT                   RLCPGNHESAGKRHHGARRTGNQHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRS
FT                   PAANKKAIIAVAHKLIVIIWHVLATGRPYQDLGADYFTTRMDPDKERRRLVAKLEAQGL
FT                   GVTLEPAA"
FT   CDS             complement(178667..178960)
FT                   /transl_table=11
FT                   /gene="Mb2448c"
FT                   /locus_tag="Mb2448c"
FT                   /product="PROBABLE TRANSPOSASE [FIRST PART]"
FT                   /note="Mb2448c, -, len: 97 aa. Similar to 5' end of
FT                   Rv2424c, len: 333 aa, from Mycobacterium tuberculosis
FT                   strain H37Rv, (100.0% identity in 67 aa overlap). Probable
FT                   transposase for IS1558, similar to IS element proteins e.g.
FT                   AL021957|Rv2177c|MTV021_10 from Mycobacterium tuberculosis
FT                   (221 aa), FASTA scores: opt: 1491, E(): 6.2e-87, (98.6%
FT                   identity in 221 aa overlap); P19780|YIS1_STRCO HYPOTHETICAL
FT                   INSERTION ELEMENT IS110 from Streptomyces coelicolor (45
FT                   aa), FASTA scores: opt: 203, E(): 1.7e-05; (27.3% identity
FT                   in 238 aa overlap); etc. Contains PS01159 WW/rsp5/WWP
FT                   domain signature. REMARK-M.bovis-M.tuberculosis: In
FT                   Mycobacterium tuberculosis strain H37Rv, Rv2424c exists as
FT                   a single gene. In Mycobacterium bovis, a frameshift due to
FT                   a 2 bp deletion (gt-*) splits Rv2424c into 2 parts, Mb2447c
FT                   and Mb2448c."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL7"
FT                   /protein_id="CAD97309.1"
FT                   /translation="MQCRAREERPGRKTDLLDAEWLVHLLECGLLRGWLIPPADIKAAR
FT                   DVIRYRRKLVEHRTSKLQRLGNASRRRDQGRQRGVLGHPQVGAGDGGGAHRR"
FT   repeat_region   complement(179027..179039)
FT                   /rpt_type=INVERTED
FT                   /note="13 bp imperfect inverted repeat, IRL, GCAGTCGCAAAAG,
FT                   flanking IS element IS1558."
FT   CDS             complement(179049..180491)
FT                   /transl_table=11
FT                   /gene="Mb2449c"
FT                   /locus_tag="Mb2449c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2449c, -, len: 480 aa. Equivalent to Rv2425c, len:
FT                   480 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 480 aa overlap). Hypothetical protein;
FT                   C-terminal half shares similarity to other unknown
FT                   conserved proteins e.g. Q53065 HYPOTHETICAL 24.3 KDA
FT                   PROTEIN from Rhodococcus erythropolis (219 aa), FASTA
FT                   scores: opt: 398, E(): 9.9e-17, (34.15% identity in 202 aa
FT                   overlap); C-terminus of O27843|MTH1815 CONSERVED PROTEIN
FT                   from Methanothermobacter thermautotrophicus (346 aa), FASTA
FT                   scores: opt: 341, E(): 3.7e-13, (31.35% identity in 233 aa
FT                   overlap); etc."
FT                   /db_xref="InterPro:IPR008912"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL6"
FT                   /protein_id="CAD97310.1"
FT                   /translation="MAARRIRAARPLAPHGLPGHLVGFVEALRGSGISVGPSETVDAGR
FT                   VMATLGLGDREVLREGIACAVLRRPDHRDTYDAMFDLWFPAALGARAVITTEDESAGSG
FT                   GLPPDDVEAMRQLLLDLLANNQDLAGKDERLVEMIARIVEAYGKYSSSRGPSFSSYQAL
FT                   KAMALDELEGKLLAGLLAPYGDEPTATQEQIAKALAAQKIAQLRRMVDAETKRRTAEQL
FT                   GREHVQMYGIPQLSENVEFLRASGEQLRQMRRVVAPLARTLATRLAARRRRARAGSIDL
FT                   RKTLRKSMSTGGVPIDLVLHKPRPARPELVVLCDVSGSVAGFSHFTLLLVHALRQQFSR
FT                   VRVFAFIDSTDEVTHMFGPESDLAIAIQRITREAGVYARDGHSDYGNAFVSFMQGFPNV
FT                   LSPRSSLLVLGDGRTNYRNPATDVLADMVTASRHAHWLNPEPKHLWGSGDSAVPRYQEV
FT                   ITMHECRSAKQLATVIDQLLPV"
FT   CDS             complement(180491..181366)
FT                   /transl_table=11
FT                   /gene="Mb2450c"
FT                   /locus_tag="Mb2450c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2450c, -, len: 291 aa. Equivalent to Rv2426c, len:
FT                   291 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 291 aa overlap). Conserved hypothetical
FT                   protein, highly similar to others e.g. Q51326|ORF4 from
FT                   Pseudomonas carboxydovorans (295 aa), FASTA scores: opt:
FT                   853, E(): 3.7e-43, (48.75% identity in 277 aa overlap);
FT                   BAB47746|MLR0088 from Rhizobium loti (309 aa), FASTA
FT                   scores: opt :809, E(): 1.5e-40, (46.5% identity in 291 aa
FT                   overlap); Q9Y9R8|APE2220 from Aeropyrum pernix (297 aa),
FT                   FASTA scores: opt: 763, E(): 7.4e-38, (47.1% identity in
FT                   261 aa overlap); etc. Contains PS00017 ATP/GTP-binding site
FT                   motif A (P-loop)."
FT                   /db_xref="GOA:Q7TYL5"
FT                   /db_xref="InterPro:IPR011704"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL5"
FT                   /protein_id="CAD97311.1"
FT                   /translation="MTVPARPTPLFADIADVSRRLAETGYLPDTATATAVFLADRLGKP
FT                   LLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARALYEWNHAKQILRIQAGSGD
FT                   WEATKTDVLSEEFLLQRPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSDFAVTVP
FT                   ELGTLTATRAPFVLLTSNATRELSEALKRRCLYLHIDFPTPELERRILLSRVPELPEHF
FT                   AEELVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQ
FT                   QRATGELRLN"
FT   CDS             complement(181393..182640)
FT                   /transl_table=11
FT                   /gene="proA"
FT                   /locus_tag="Mb2451c"
FT                   /product="PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE
FT                   PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE)
FT                   (GLUTAMYL-GAMMA-SEMIALDEHYDE DEHYDROGENASE)"
FT                   /EC_number="1.2.1.41"
FT                   /note="Mb2451c, proA, len: 415 aa. Equivalent to Rv2427c,
FT                   len: 415 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 415 aa overlap). Probable proA,
FT                   gamma-glutamyl phosphate reductase protein (EC 1.2.1.41),
FT                   equivalent to Q9CBZ7|ML1458|PROA [GAMMA]-GLUTAMYL PHOSPHATE
FT                   REDUCTASE from Mycobacterium leprae (409 aa), FASTA scores:
FT                   opt: 2120, E(): 7.4e-118, (81.9% identity in 409 aa
FT                   overlap). Also highly similar or similar to other
FT                   GAMMA-GLUTAMYL PHOSPHATE REDUCTASES PROTEINS (GPR) e.g.
FT                   Q9RDK1|PROA from Streptomyces coelicolor (428 aa), FASTA
FT                   scores: opt: 1073, E(): 4.6e-56, (60.4% identity in 429 aa
FT                   overlap); P45638|PROA_CORGL from Corynebacterium glutamicum
FT                   (432 aa), FASTA scores: opt: 993, E(): 2.4e-51, (58.5%
FT                   identity in 417 aa overlap); P96489|PROA_STRTR
FT                   GAMMA-GLUTAMYL PHOSPHATE REDUCTASE from Streptococcus
FT                   thermophilus (416 aa), FASTA scores: opt: 863, E():
FT                   1.1e-43, (49.15% identity in 413 aa overlap); etc. BELONGS
FT                   TO THE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE FAMILY."
FT                   /db_xref="GOA:P65789"
FT                   /db_xref="HSSP:1O20"
FT                   /db_xref="InterPro:IPR012134"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65789"
FT                   /protein_id="CAD97312.1"
FT                   /translation="MTVPAPSQLDLRQEVHDAARRARVAARRLASLPTTVKDRALHAAA
FT                   DELLAHRDQILAANAEDLNAAREADTPAAMLDRLSLNPQRVDGIAAGLRQVAGLRDPVG
FT                   EVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLTLKSGNAALLRGSSSAAK
FT                   SNEALVAVLRTALVGLELPADAVQLLSAADRATVTHLIQARGLVDVVIPRGGAGLIEAV
FT                   VRDAQVPTIETGVGNCHVYVHQAADLDVAERILLNSKTRRPSVCNAAETLLVDAAIAET
FT                   ALPRLLAALQHAGVTVHLDPDEADLRREYLSLDIAVAVVDGVDAAIAHINEYGTGHTEA
FT                   IVTTNLDAAQRFTEQIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPEL
FT                   TSTKWIAWGAGHTRPA"
FT   CDS             complement(182723..183028)
FT                   /pseudo
FT                   /transl_table=11
FT                   /gene="Mb2452c"
FT                   /locus_tag="Mb2452c"
FT                   /note="Mb2452c, -, len: 101 aa. Equivalent to the second
FT                   part of oxyR' pseudogene (see citation below)."
FT                   /db_xref="PSEUDO:CAD97313.1"
FT   CDS             complement(183029..183229)
FT                   /pseudo
FT                   /transl_table=11
FT                   /gene="Mb2453c"
FT                   /locus_tag="Mb2453c"
FT                   /note="Mb2453c, -, len: 66 aa. Equivalent to the first part
FT                   of oxyR' pseudogene (see citation below)."
FT   CDS             183356..183943
FT                   /transl_table=11
FT                   /gene="ahpC"
FT                   /locus_tag="Mb2454"
FT                   /product="ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC
FT                   (ALKYL HYDROPEROXIDASE C)"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2454, ahpC, len: 195 aa. Equivalent to Rv2428,
FT                   len: 195 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 195 aa overlap). ahpC, alkyl
FT                   hydroperoxide reductase C (EC 1.-.-.-) (see citations
FT                   below), equivalent to other alkyl hydroperoxide reductases
FT                   C mycobacterial proteins e.g. Q9CBF5|AHPC|ML2042 ALKYL
FT                   HYDROPEROXIDE REDUCTASE from Mycobacterium leprae (195 aa)
FT                   FASTA scores: opt: 1183, E(): 2.6e-72, (88.20% identity in
FT                   195 aa overlap); O87323|AHPC from Mycobacterium marinum
FT                   (195 aa), FASTA scores: opt: 1215, E(): 1.9e-74, (90.8%
FT                   identity in 195 aa overlap); Q57413|AHPC|AVI-3 from
FT                   Mycobacterium avium (195 aa), FASTA scores: opt: 1201, E():
FT                   1.6e-73, (90.25% identity in 195 aa overlap). Also highly
FT                   similar to others from other organisms e.g. Q9FBP5|AHPC
FT                   ALKYL HYDROPEROXIDE REDUCTASE from Streptomyces coelicolor
FT                   (184 aa), FASTA scores: opt: 768, E(): 1.7e-44, (62.45%
FT                   identity in 189 aa overlap); etc."
FT                   /db_xref="GOA:Q79CV0"
FT                   /db_xref="InterPro:IPR017936"
FT                   /db_xref="UniProtKB/TrEMBL:Q79CV0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97315.1"
FT                   /translation="MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPG
FT                   KWRVVFFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQHNDLK
FT                   TLPFPMLSDIKRELSQAAGVLNADGVADRVTFIVDPNNEIQFVSATAGSVGRNVDEVLR
FT                   VLDALQSDELCACNWRKGDPTLDAGELLKASA"
FT   CDS             183969..184502
FT                   /transl_table=11
FT                   /gene="ahpD"
FT                   /locus_tag="Mb2455"
FT                   /product="ALKYL HYDROPEROXIDE REDUCTASE D PROTEIN AHPD
FT                   (ALKYL HYDROPEROXIDASE D)"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2455, ahpD, len: 177 aa. Equivalent to Rv2429,
FT                   len: 177 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 177 aa overlap). ahpD, alkyl
FT                   hydroperoxide reductase (EC 1.-.-.-), similar to other
FT                   alkyl hydroperoxide reductases D proteins e.g. Q9RN73|AHPD
FT                   from Streptomyces coelicolor (178 aa), FASTA scores: opt:
FT                   611, E(): 1.4e-33, (57.4% identity in 169 aa overlap);
FT                   Q50441|AHPD_MYCSM AHPD PROTEIN (FRAGMENT) from
FT                   Mycobacterium smegmatis (52 aa), FASTA score: opt:196."
FT                   /db_xref="GOA:P0A5N5"
FT                   /db_xref="InterPro:IPR003779"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5N5"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97316.1"
FT                   /translation="MSIEKLKAALPEYAKDIKLNLSSITRSSVLDQEQLWGTLLASAAA
FT                   TRNPQVLADIGAEATDHLSAAARHAALGAAAIMGMNNVFYRGRGFLEGRYDDLRPGLRM
FT                   NIIANPGIPKANFELWSFAVSAINGCSHCLVAHEHTLRTVGVDREAIFEALKAAAIVSG
FT                   VAQALATIEALSPS"
FT   CDS             complement(184499..185083)
FT                   /transl_table=11
FT                   /gene="PPE41"
FT                   /locus_tag="Mb2456c"
FT                   /product="PPE FAMILY PROTEIN"
FT                   /note="Mb2456c, PPE41, len: 194 aa. Equivalent to Rv2430c,
FT                   len: 194 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 194 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PPE family similar to others
FT                   e.g. AAK46014|Rv1745|MT1745 from Mycobacterium tuberculosis
FT                   (385 aa) FASTA scores: opt: 389, E(): 1.2e-17, (35.95%
FT                   identity in 192 aa overlap); etc."
FT                   /db_xref="InterPro:IPR000030"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL4"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97317.1"
FT                   /translation="MHFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSF
FT                   NRTLLSLMDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMV
FT                   PLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSK
FT                   LTPWKAPPPIAHSTVLVAPVSPSTASSRTDT"
FT   CDS             complement(185130..185429)
FT                   /transl_table=11
FT                   /gene="PE25"
FT                   /locus_tag="Mb2457c"
FT                   /product="PE FAMILY PROTEIN"
FT                   /note="Mb2457c, PE25, len: 99 aa. Equivalent to Rv2431c,
FT                   len: 99 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 99 aa overlap). Member of the
FT                   Mycobacterium tuberculosis PE family (see first citation
FT                   below), similar to others e.g. AAK47158|MT2839 from
FT                   Mycobacterium tuberculosis (275 aa) FASTA scores: opt: 194,
FT                   E(): 2.5e-06, (40.0% identity in 95 aa overlap); etc."
FT                   /db_xref="InterPro:IPR000084"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97318.1"
FT                   /translation="MSFVITNPEALTVAATEVRRIRDRAIQSDAQVAPMTTAVRPPAAD
FT                   LVSEKAATFLVEYARKYRQTIAAAAVVLEEFAHALTTGADKYATAEADNIKTFS"
FT   CDS             complement(185600..186010)
FT                   /transl_table=11
FT                   /gene="Mb2458c"
FT                   /locus_tag="Mb2458c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2458c, -, len: 136 aa. Equivalent to Rv2432c, len:
FT                   136 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 136 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL2"
FT                   /protein_id="CAD97319.1"
FT                   /translation="MTVRAEHCRGAGGCDECPSVMPEHPTALFHDVAAIALAQPGAEPG
FT                   AMMGFPCRPALLPHLSRAVMRCVRTRSASTSLGVSVIAGQLPAAGSRHRLGAPCRHVRW
FT                   WLASDGHWGMVSYIPTALNVSMGGIVGWRCVP"
FT   CDS             complement(186007..186297)
FT                   /transl_table=11
FT                   /gene="Mb2459c"
FT                   /locus_tag="Mb2459c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2459c, -, len: 96 aa. Equivalent to Rv2433c, len:
FT                   96 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 96 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL1"
FT                   /protein_id="CAD97320.1"
FT                   /translation="MGLRDADERWDTVGQAIGLFLRGHTLRTAAPTALIVGTVLCAVNQ
FT                   GATLAEGAATIGTWVRMVINYLVPFLVASVGYLGARRGVRRASGRSDPSAQ"
FT   CDS             complement(186278..187723)
FT                   /transl_table=11
FT                   /gene="Mb2460c"
FT                   /locus_tag="Mb2460c"
FT                   /product="PROBABLE CONSERVED TRANSMEMBRANE PROTEIN"
FT                   /note="Mb2460c, -, len: 481 aa. Equivalent to Rv2434c, len:
FT                   481 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 481 aa overlap). Probable conserved
FT                   transmembrane protein, with some similarity to
FT                   BAB48444|MLR0973 PROBABLE INTEGRAL MEMBRANE PROTEIN from
FT                   Rhizobium loti (410 aa), FASTA scores: opt: 298, E():
FT                   4.1e-11, (27.25% identity in 389 aa overlap); and also
FT                   similarity with other hypothetical proteins and/or putative
FT                   integral membrane proteins."
FT                   /db_xref="GOA:Q7TYL0"
FT                   /db_xref="InterPro:IPR014710"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYL0"
FT                   /protein_id="CAD97321.1"
FT                   /translation="MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQAS
FT                   LLRNYLLPLGAVLLLLVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQ
FT                   SWRKRLPAIFVDVARFALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQ
FT                   IVSGLFMLFEQPFRIDDWLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTN
FT                   LSRPAGAHECSITTTFSTSDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTV
FT                   RLTSPADEGPTQATFLRWVWYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSS
FT                   SDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKG
FT                   TFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQ
FT                   QAIRRDLHQSPAAAGEHRGPARR"
FT   CDS             complement(187720..189912)
FT                   /transl_table=11
FT                   /gene="Mb2461c"
FT                   /locus_tag="Mb2461c"
FT                   /product="PUTATIVE CYCLASE (ADENYLYL-OR
FT                   GUANYLYL-)(ADENYLATE-OR GUANYLATE-)"
FT                   /EC_number="4.6.1.-"
FT                   /note="Mb2461c, -, len: 730 aa. Equivalent to Rv2435c, len:
FT                   730 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 730 aa overlap). Probably a cyclase
FT                   (adenylyl- or guanylyl-cyclase; EC 4.6.1.1 or 4.6.1.2
FT                   respectively); C-terminal domain (aa 500-730) similar to
FT                   domain at C-terminus of a series of adenylate/guanylate
FT                   cyclases (EC 4.6.-.-) e.g. O30820|CYA AAK45931|MT1661 from
FT                   Mycobacterium tuberculosis (443 aa) FASTA scores: opt: 446,
FT                   E(): 1.3e-19, (30.55% identity in 301 aa overlap);
FT                   BAB50179|MLL3242 CYCLASE (ADENYLYL OR GUANYLYL) from
FT                   Rhizobium loti (356 aa), FASTA scores: opt: 372, E():
FT                   3.4e-15, (28.75% identity in 219 aa overlap); etc. BELONGS
FT                   TO ADENYLYL CYCLASE CLASS-4/GUANYLYL CYCLASE FAMILY."
FT                   /db_xref="GOA:Q7TYK9"
FT                   /db_xref="HSSP:1AZS"
FT                   /db_xref="InterPro:IPR003660"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK9"
FT                   /protein_id="CAD97322.1"
FT                   /translation="MTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLL
FT                   LTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGL
FT                   TVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSP
FT                   AQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDT
FT                   RGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVP
FT                   TAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRS
FT                   DSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTS
FT                   TDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICV
FT                   ASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEE
FT                   LLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGN
FT                   ELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRI
FT                   VDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYV
FT                   TSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS"
FT   CDS             190393..191307
FT                   /transl_table=11
FT                   /gene="rbsK"
FT                   /locus_tag="Mb2462"
FT                   /product="RIBOKINASE RBSK"
FT                   /EC_number="2.7.1.15"
FT                   /note="Mb2462, rbsK, len: 304 aa. Equivalent to Rv2436,
FT                   len: 304 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.3% identity in 304 aa overlap). Probable rbsK,
FT                   ribokinase (EC 2.7.1.15), similar to others e.g.
FT                   Q9RZ99|DRA0055 from Deinococcus radiodurans (300 aa) FASTA
FT                   scores: opt: 485, E(): 9.1e-21, (44.55% identity in 301 aa
FT                   overlap); P36945|P96733|RBSK_BACSU from Bacillus subtilis
FT                   (293 aa), FASTA scores: opt: 398, E(): 8.5e-16, (36.35%
FT                   identity in 297 aa overlap);
FT                   P05054|RBSK_ECOLI|B3752|Z5253|ECS4694 from Escherichia coli
FT                   strain K12 (309 aa), FASTA scores: opt: 387, E(): 3.8e-15,
FT                   (34.7% identity in 314 aa overlap); etc. Contains PS00583
FT                   pfkB family of carbohydrate kinases signature 1. BELONGS TO
FT                   THE PFKB FAMILY OF CARBOHYDRATE KINASES."
FT                   /db_xref="GOA:Q7TYK8"
FT                   /db_xref="HSSP:1GQT"
FT                   /db_xref="InterPro:IPR002139"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK8"
FT                   /protein_id="CAD97323.1"
FT                   /translation="MANASETNVGPMAPRVCVVGSVNMDLTFVVDALPRPGETVLAASL
FT                   TRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAAQLRAHLRANAVGLDRTVTVPGPSG
FT                   TAIIVVDASAENTVLVAPGANAHLTPVPSAVANCDVLLTQLEIPVATALAAARAAQSAD
FT                   AVVMVNASPAGQDRSSLQDLAAIADVVIANEHEANDWPSPPTHFVITLGVRGARYVGAD
FT                   GVFEVPAPTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERLRALRRACAAGVLATLVSG
FT                   AGDCAPAAAAIDAALRANRHNGS"
FT   CDS             191539..191958
FT                   /transl_table=11
FT                   /gene="Mb2463"
FT                   /locus_tag="Mb2463"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2463, -, len: 139 aa. Equivalent to Rv2437, len:
FT                   139 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 139 aa overlap). Conserved hypothetical
FT                   protein, with some similarity to CONSERVED HYPOTHETICAL
FT                   PROTEINS e.g. O06539|RV1139C|MTCI65.06c from Mycobacterium
FT                   tuberculosis (166 aa); AAK45430|MT1172 from Mycobacterium
FT                   tuberculosis (124 aa), FASTA scores: opt: 166, E():
FT                   0.00013, (35.7% identity in 112 aa overlap);
FT                   BAB48937|Mlr1600 from Rhizobium loti (222 aa), FASTA
FT                   scores: opt: 163 ,E(): 0.00033, (28.1% identity in 121 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:Q7TYK7"
FT                   /db_xref="InterPro:IPR007269"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK7"
FT                   /protein_id="CAD97324.1"
FT                   /translation="MLQRTNVVQPLNTLRMVWIQVAGIIPATAGIAATVYAQLAMGDSW
FT                   RIGVDEQENTTLVRTGPFKWVRHPIYTAMMAFGLGLLLVTPNLVALAGFILLVATLEVH
FT                   VRRVEEPYLLRTHSAVYRGYTASVGRFVPGVGLIR"
FT   CDS             complement(191955..193994)
FT                   /transl_table=11
FT                   /gene="nadE"
FT                   /locus_tag="Mb2464c"
FT                   /product="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE
FT                   (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING])"
FT                   /EC_number="6.3.5.1"
FT                   /note="Mb2464c, nadE, len: 679 aa. Equivalent to Rv2438c,
FT                   len: 679 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 679 aa overlap). nadE,
FT                   glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (see
FT                   citation below), equivalent to Q9CBZ6|NADE_MYCLE|ML1463
FT                   Glutamine-dependent NAD(+) synthetase from Mycobacterium
FT                   leprae (680 aa), FASTA scores: opt: 3877, E(): 0. Also
FT                   similar to others e.g. O83759|NADE_TREPA|TP0780 from
FT                   Treponema pallidum (679 aa), FASTA scores: opt: 543, E():
FT                   1.1e-25; O74940|NADE_SCHPO|SPCC553.02 from
FT                   Schizosaccharomyces pombe (Fission yeast) (700 aa), FASTA
FT                   scores: opt: 354, E(): 4.7e-14 ; P38795|NADE_YEAST|YHR074W
FT                   from Saccharomyces cerevisiae (Baker's yeast) (714 aa),
FT                   FASTA scores: opt: 339, E(): 4e-13; etc. Contains PS00591
FT                   Glycosyl hydrolases family 10 active site. BELONGS TO THE
FT                   NAD SYNTHETASE FAMILY IN THE C-TERMINAL SECTION. N-terminus
FT                   shorter since first submission."
FT                   /db_xref="GOA:P0A5L7"
FT                   /db_xref="InterPro:IPR014729"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A5L7"
FT                   /protein_id="CAD97325.1"
FT                   /translation="MNFYSAYQHGFVRVAACTHHTTIGDPAANAASVLDMARACHDDGA
FT                   ALAVFPELTLSGYSIEDVLLQDSLLDAVEDALLDLVTESADLLPVLVVGAPLRHRHRIY
FT                   NTAVVIHRGAVLGVVPKSYLPTYREFYERRQMAPGDGERGTIRIGGADVAFGTDLLFAA
FT                   SDLPGFVLHVEICEDMFVPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASA
FT                   RCLAAYVYAAAGEGESTTDLAWDGQTMIWENGALLAESERFPKGVRRSVADVDTELLRS
FT                   ERLRMGTFDDNRRHHRELTESFRRIDFALDPPAGDIGLLREVERFPFVPADPQRLQQDC
FT                   YEAYNIQVSGLEQRLRALDYPKVVIGVSGGLDSTHALIVATHAMDREGRPRSDILAFAL
FT                   PGFATGEHTKNNAIKLARALGVTFSEIDIGDTARLMLHTIGHPYSVGEKVYDVTFENVQ
FT                   AGLRTDYLFRIANQRGGIVLGTGDLSELALGWSTYGVGDQMSHYNVNAGVPKTLIQHLI
FT                   RWVISAGEFGEKVGEVLQSVLDTEITPELIPTGEEELQSSEAKVGPFALQDFSLFQVLR
FT                   YGFRPSKIAFLAWHAWNDAERGNWPPGFPKSERPSYSLAEIRHWLQIFVQRFYSFSQFK
FT                   RSALPNGPKVSHGGALSPRGDWRAPSDMSARIWLDQIDREVPKG"
FT   CDS             193872..194150
FT                   /transl_table=11
FT                   /gene="Mb2465"
FT                   /locus_tag="Mb2465"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2465, -, len: 92 aa. Equivalent to Rv2438A, len:
FT                   92 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 92 aa overlap). Conserved hypothetical
FT                   protein, showing few similarity with various enzymes e.g.
FT                   part of O83441|VAA1_TREPA|ATPA1|TP0426 V-TYPE ATP SYNTHASE
FT                   ALPHA CHAIN 1 (EC 3.6.1.34) from Treponema pallidum (589
FT                   aa), FASTA scores: opt: 110, E(): 1.5, (40.3% identity in
FT                   72 aa overlap); N-terminus of O95178|NIGM_HUMAN
FT                   NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT PRECURSOR (EC
FT                   1.6.5.3) (EC 1.6.99.3) from Homo sapiens (105 aa), FASTA
FT                   scores: opt: 109, E(): 1.5, (35.5% identity in 62 aa
FT                   overlap); N-terminus of Q9HJ76|TA1096 PROBABLE GLYCEROL
FT                   KINASE from Thermoplasma acidophilum (488 aa); etc."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK6"
FT                   /protein_id="CAD97326.1"
FT                   /translation="MARTGHVQYRRGVGRRVTDGGVVSAGGNAHEPVLVGGVKVHRPFI
FT                   VAQRRQNARITRRVSTLDTVESPALLADGGIDRRGDATDWAAADPGP"
FT   CDS             complement(194280..195410)
FT                   /transl_table=11
FT                   /gene="proB"
FT                   /locus_tag="Mb2466c"
FT                   /product="PROBABLE GLUTAMATE 5-KINASE PROTEIN PROB
FT                   (GAMMA-GLUTAMYL KINASE) (GK)"
FT                   /EC_number="2.7.2.11"
FT                   /note="Mb2466c, proB, len: 376 aa. Equivalent to Rv2439c,
FT                   len: 376 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 376 aa overlap). Probable proB,
FT                   glutamate 5-kinase protein (GK) (EC 2.7.2.11), equivalent
FT                   to Q9CBZ5|PROB|ML1464 from Mycobacterium leprae (367 aa)
FT                   FASTA scores: opt: 1937, E(): 1.1e-102, (84.4% identity in
FT                   366 aa overlap). Also highly similar to other glutamate
FT                   5-kinase proteins e.g. P46546|PROB_CORGL from
FT                   Corynebacterium glutamicum (Brevibacterium flavum) (369
FT                   aa), FASTA scores: opt: 1241, E(): 3e-63, (54.35% identity
FT                   in 368 aa overlap); Q9ZG98|PROB_MEIRU GLUTAMATE 5-KINASE
FT                   from Meiothermus ruber (390 aa), FASTA scores: opt: 825,
FT                   E(): 1.2e-39, (45.05% identity in 353 aa overlap);
FT                   Q9RDJ9|PROB|SCC123.25c from Streptomyces coelicolor (374
FT                   aa), FASTA scores: opt: 1193, E(): 1.6e-60, (55.85%
FT                   identity in 367 aa overlap); etc. Contains PS00902
FT                   Glutamate 5-kinase signature. BELONGS TO THE GLUTAMATE
FT                   5-KINASE FAMILY."
FT                   /db_xref="GOA:P59958"
FT                   /db_xref="InterPro:IPR002478"
FT                   /db_xref="UniProtKB/Swiss-Prot:P59958"
FT                   /protein_id="CAD97327.1"
FT                   /translation="MRSPHRDAIRTARGLVVKVGTTALTTPSGMFDAGRLAGLAEAVER
FT                   RMKAGSDVVIVSSGAIAAGIEPLGLSRRPKDLATKQAAASVGQVALVNSWSAAFARYGR
FT                   TVGQVLLTAHDISMRVQHTNAQRTLDRLRALHAVAIVNENDTVATNEIRFGDNDRLSAL
FT                   VAHLVGADALVLLSDIDGLYDCDPRKTADATFIPEVSGPADLDGVVAGRSSHLGTGGMA
FT                   SKVSAALLAADAGVPVLLAPAADAATALADASVGTVFAARPARLSARRFWVRYAAEATG
FT                   ALTLDAGAVRAVVRQRRSLLAAGITAVSGRFCGGDVVELRAPDAAMVARGVVAYDASEL
FT                   ATMVGRSTSELPGELRRPVVHADDLVAVSAKQAKQV"
FT   CDS             complement(195410..196849)
FT                   /transl_table=11
FT                   /gene="obg"
FT                   /locus_tag="Mb2467c"
FT                   /product="PROBABLE GTP1/OBG-FAMILY GTP-BINDING PROTEIN OBG"
FT                   /note="Mb2467c, obg, len: 479 aa. Equivalent to Rv2440c,
FT                   len: 479 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 479 aa overlap). Probable obg,
FT                   nucleotide-binding protein, equivalent to Q9CBZ4|ML1465
FT                   GTP1/OBG-FAMILY GTP-BINDING PROTEIN from Mycobacterium
FT                   leprae (478 aa), FASTA scores: opt: 1328, E(): 8.4e-70,
FT                   (58.9% identity in 479 aa overlap). Also highly similar to
FT                   others e.g. P95722|OBG GTP-BINDING PROTEIN from
FT                   Streptomyces coelicolor (478 aa), FASTA scores: opt: 1311,
FT                   E(): 8.2e-69, (60.7% identity in 476 aa overlap);
FT                   P20964|OBG_BACSU SPO0B-ASSOCIATED GTP-BINDING PROTEIN from
FT                   Bacillus subtilis (428 aa), FASTA scores: opt: 1006, E():
FT                   3.9e-51, (42.9% identity in 436 aa overlap);
FT                   Q9KDK0|OBG|BH1213 GTP-BINDING PROTEIN INVOLVED IN
FT                   INITIATION OF SPORULATION from Bacillus halodurans (427
FT                   aa), FASTA scores: opt: 978, E(): 1.7e-49, (41.95% identity
FT                   in 436 aa overlap); etc. Highly similar (identical but
FT                   shorter 5 aa) to AAK46813|MT2516 GTP-BINDING PROTEIN from
FT                   Mycobacterium tuberculosis strain CDC1551 (484 aa), FASTA
FT                   scores: opt: 3205, E(): 7.9e-179, (100% identity in 479 aa
FT                   overlap). Contains PS00017 ATP/GTP-binding site motif A
FT                   (P-loop). BELONGS TO THE GTP1/OBG FAMILY."
FT                   /db_xref="GOA:Q7TYK5"
FT                   /db_xref="HSSP:1JAL"
FT                   /db_xref="InterPro:IPR002917"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK5"
FT                   /protein_id="CAD97328.1"
FT                   /translation="MPRFVDRVVIHTRAGSGGNGCASVHREKFKPLGGPDGGNGGRGGS
FT                   IVFVVDPQVHTLLDFHFRPHLTAASGKHGMGNNRDGAAGADLEVKVPEGTVVLDENGRL
FT                   LADLVGAGTRFEAAAGGRGGLGNAALASRVRKAPGFALLGEKGQSRDLTLELKTVADVG
FT                   LVGFPSAGKSSLVSAISAAKPKIADYPFTTLVPNLGVVSAGEHAFTVADVPGLIPGASR
FT                   GRGLGLDFLRHIERCAVLVHVVDCATAEPGRDPISDIDALETELACYTPTLQGDAALGD
FT                   LAARPRAVVLNKIDVPEARELAEFVRDDIAQRGWPVFCVSTATRENLQPLIFGLSQMIS
FT                   DYNAARPVAVPRRPVIRPIPVDDSGFTVEPDGHGGFVVSGARPERWIDQTNFDNDEAVG
FT                   YLADRLARLGVEEELLRLGARSGCAVTIGEMTFDWEPQTPAGEPVAMSGRGTDPRLDSN
FT                   KRVGAAERKAARSRRREHGDG"
FT   CDS             complement(196935..197195)
FT                   /transl_table=11
FT                   /gene="rpmA"
FT                   /locus_tag="Mb2468c"
FT                   /product="PROBABLE 50S RIBOSOMAL PROTEIN L27 RPMA"
FT                   /note="Mb2468c, rpmA, len: 86 aa. Equivalent to Rv2441c,
FT                   len: 86 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 86 aa overlap). Probable rpmA, 50S
FT                   RIBOSOMAL PROTEINS L27, equivalent to Q9CBZ3|RL27_MYCLE
FT                   from Mycobacterium leprae (88 aa), FASTA scores: opt: 504,
FT                   E(): 7.6e-28, (93.2% identity in 81 aa overlap). Also
FT                   highly similar to others e.g. P95757|RL27_STRGR from
FT                   Streptomyces griseus (85 aa), FASTA scores: opt: 442, E():
FT                   1.2e-23, (81.5% identity in 81 aa overlap); etc. Contains
FT                   PS00831 Ribosomal protein L27 signature. BELONGS TO THE
FT                   L27P FAMILY OF RIBOSOMAL PROTEINS."
FT                   /db_xref="GOA:P66128"
FT                   /db_xref="InterPro:IPR018261"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66128"
FT                   /protein_id="CAD97329.1"
FT                   /translation="MAHKKGASSSRNGRDSAAQRLGVKRYGGQVVKAGEILVRQRGTKF
FT                   HPGVNVGRGGDDTLFAKTAGAVEFGIKRGRKTVSIVGSTTA"
FT   CDS             complement(197210..197524)
FT                   /transl_table=11
FT                   /gene="rplU"
FT                   /locus_tag="Mb2469c"
FT                   /product="PROBABLE 50S RIBOSOMAL PROTEIN L21 RPLU"
FT                   /note="Mb2469c, rplU, len: 104 aa. Equivalent to Rv2442c,
FT                   len: 104 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 104 aa overlap). Probable rplU, 50S
FT                   RIBOSOMAL PROTEIN L21, equivalent to Q9CBZ2|RL21_MYCLE from
FT                   Mycobacterium leprae (103 aa), FASTA scores: opt: 579, E():
FT                   4.8e-31, (91.1% identity in 102 aa overlap). Also highly
FT                   similar to others e.g. P95756|RL21_STRGR from Streptomyces
FT                   griseus (106 aa), FASTA scores: opt: 362, E(): 5.4e-17,
FT                   (56.0% identity in 100 aa overlap); etc."
FT                   /db_xref="GOA:P66118"
FT                   /db_xref="InterPro:IPR018258"
FT                   /db_xref="UniProtKB/Swiss-Prot:P66118"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97330.1"
FT                   /translation="MMATYAIVKTGGKQYKVAVGDVVKVEKLESEQGEKVSLPVALVVD
FT                   GATVTTDAKALAKVAVTGEVLGHTKGPKIRIHKFKNKTGYHKRQGHRQQLTVLKVTGIA
FT                   "
FT   CDS             197872..199347
FT                   /transl_table=11
FT                   /gene="dctA"
FT                   /locus_tag="Mb2470"
FT                   /product="PROBABLE C4-DICARBOXYLATE-TRANSPORT TRANSMEMBRANE
FT                   PROTEIN DCTA"
FT                   /note="Mb2470, dctA, len: 491 aa. Equivalent to Rv2443,
FT                   len: 491 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 491 aa overlap). Probable dctA,
FT                   C4-dicarboxylate-transport transmembrane protein, similar
FT                   to other C4-DICARBOXYLATE TRANSPORT PROTEINS e.g.
FT                   AAK46817|MT2519 from Mycobacterium tuberculosis strain
FT                   CDC1551 (491 aa); Q9L1K8|SC6A11.12 PUTATIVE
FT                   SODIUM:DICARBOXYLATE SYMPORTER from Streptomyces coelicolor
FT                   (466 aa), FASTA scores: opt: 1797, E(): 2.9e-98, (61.3%
FT                   identity in 452 aa overlap); Q9RRG7|DR2525 from Deinococcus
FT                   radiodurans (463 aa); P50334|DCTA_SALTY from Salmonella
FT                   typhimurium (428 aa) FASTA scores: opt: 1241, E(): 1.3e-65,
FT                   (47.2% identity in 415 aa overlap); etc. BELONGS TO THE
FT                   SODIUM DICARBOXYLATE SYMPORTER FAMILY (SDF) (DAACS
FT                   FAMILY)."
FT                   /db_xref="GOA:Q7TYK4"
FT                   /db_xref="InterPro:IPR001991"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK4"
FT                   /protein_id="CAD97331.1"
FT                   /translation="MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAP
FT                   STGKSLTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLTMSSV
FT                   ALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGFIQQIIPRSLPSALTE
FT                   GNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKLVFKVLVMVLWLAPIGAFGAIAN
FT                   IVATTGFNAVTNLLLLMAGFYLTCVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIF
FT                   ATSSSEVVLPRLITKMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHR
FT                   LTWGEQIALLAFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEA
FT                   RSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMVDPHDEEPPAATPHGG
FT                   GVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG"
FT   CDS             complement(199286..202147)
FT                   /transl_table=11
FT                   /gene="rne"
FT                   /locus_tag="Mb2471c"
FT                   /product="POSSIBLE RIBONUCLEASE E RNE"
FT                   /EC_number="3.1.-.-"
FT                   /note="Mb2471c, rne, len: 953 aa. Equivalent to Rv2444c,
FT                   len: 953 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 953 aa overlap). Possible rne,
FT                   ribonuclease E (EC 3.1.-.-), highly similar to others e.g.
FT                   Q9CBZ1|ML1468 POSSIBLE RIBONUCLEASE from Mycobacterium
FT                   leprae (924 aa), FASTA scores: opt: 3713, E(): 2.4e-174,
FT                   (74.2% identity in 966 aa overlap); Q9SI08|AT2G04270
FT                   PUTATIVE RIBONUCLEASE E from Arabidopsis thaliana (502 aa),
FT                   FASTA scores: opt: 674, E(): 7.5e-26, (31.2% identity in
FT                   410 aa overlap); etc. Similar at C-terminal end to
FT                   P21513|RNE_ECOLI|AMS|HMP1|B1084 ribonuclease E (EC 3.1.4.-)
FT                   (RNASE E) from Escherichia coli strain K12 (1061 aa), FASTA
FT                   scores: opt: 554, E(): 9.9e-20, (37.8% identity in 386 aa
FT                   overlap). Also similar in medium part to several
FT                   cytoplasmic axial filament proteins e.g. Q9HVU4|CAFA|PA4477
FT                   from Pseudomonas aeruginosa (485 aa), FASTA scores: opt:
FT                   664, E(): 2.3e-25, (42.8% identity in 418 aa overlap); etc.
FT                   Equivalent to AAK46818 from Mycobacterium tuberculosis
FT                   strain CDC1551 (621 aa) but longer 332 aa in N-terminal
FT                   part. SEEMS TO BELONG TO THE RNE FAMILY."
FT                   /db_xref="GOA:Q7TYK3"
FT                   /db_xref="InterPro:IPR019307"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK3"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97332.1"
FT                   /translation="MIDGAPPSDPPEPSQHEELPDRLRVHSLARTLGTTSRRVLDALTA
FT                   LDGRVRSAHSTVDRVDAVRVRDLLATHLETAGVLAASVHAPEASEEPESRLMLETQETR
FT                   NADVERPHYMPLFVAPQPIPEPLADDEDVDDGPDYVADDSDADDEGQLDRPANRRRRRG
FT                   RRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDEN
FT                   GSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGG
FT                   SGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVR
FT                   TEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGR
FT                   GRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLAG
FT                   RFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVA
FT                   RLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNT
FT                   INEYVNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLPSGGTL
FT                   VIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFID
FT                   MVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCS
FT                   GRGILLHADPVDSAAATGRKSEPGARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMF
FT                   KAMAAGLSSLAGRGDEESGEPAAELAEQAGDQPPTDLDDTAQADFEDTEDTDEDEDELD
FT                   ADEDLEDLDDEDLDEDLDVEDSDSDDEDSDEDAADADVDEEDAAGLDGSPGEVDVPGVT
FT                   ELAPTRPRRRVAGRPAGPPIRLD"
FT   CDS             complement(202477..202887)
FT                   /transl_table=11
FT                   /gene="ndkA"
FT                   /locus_tag="Mb2472c"
FT                   /standard_name="ndk"
FT                   /product="PROBABLE NUCLEOSIDE DIPHOSPHATE KINASE NDKA (NDK)
FT                   (NDP KINASE) (NUCLEOSIDE-2-P KINASE)"
FT                   /EC_number="2.7.4.6"
FT                   /note="Mb2472c, ndkA, len: 136 aa. Equivalent to Rv2445c,
FT                   len: 136 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 136 aa overlap). Probable ndkA
FT                   (alternate gene name: ndk), nucleoside diphosphate kinase
FT                   (EC 2.7.4.6), equivalent to Q9CBZ0|NDK|ML1469 from
FT                   Mycobacterium leprae (136 aa), FASTA scores: opt: 762, E():
FT                   1.5e-42, (87.4% identity in 135 aa overlap); and O85501|NDK
FT                   from Mycobacterium smegmatis (139 aa), FASTA scores: opt:
FT                   714, E(): 1.9e-39, (80.7% identity in 135 aa overlap). Also
FT                   highly similar to others e.g. P50589|NDK_STRCO from
FT                   Streptomyces coelicolor (137 aa), FASTA scores: opt: 535,
FT                   6.8e-28, (60.3% identity in 136 aa overlap);
FT                   O29491|NDK_ARCFU|AF0767 from Archaeoglobus fulgidus (151
FT                   aa), FASTA scores: opt: 521, E(): 5.9e-27, (58.0% identity
FT                   in 131 aa overlap); P31103|NDK_BACSU from Bacillus subtilis
FT                   (151 aa), FASTA scores: opt: 515, E(): 1.4e-26, (56.5%
FT                   identity in 131 aa overlap); etc. BELONGS TO THE NDK
FT                   FAMILY."
FT                   /db_xref="GOA:P84283"
FT                   /db_xref="InterPro:IPR001564"
FT                   /db_xref="UniProtKB/Swiss-Prot:P84283"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97333.1"
FT                   /translation="MTERTLVLIKPDGIERQLIGEIISRIERKGLTIAALQLRTVSAEL
FT                   ASQHYAEHEGKPFFGSLLEFITSGPVVAAIVEGTRAIAAVRQLAGGTDPVQAAAPGTIR
FT                   GDFALETQFNLVHGSDSAESAQREIALWFPGA"
FT   CDS             complement(202930..203301)
FT                   /transl_table=11
FT                   /gene="Mb2473c"
FT                   /locus_tag="Mb2473c"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN"
FT                   /note="Mb2473c, -, len: 123 aa. Equivalent to Rv2446c, len:
FT                   123 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 123 aa overlap). Probable conserved
FT                   integral membrane protein, highly similar to Q9CBY9|ML1470
FT                   CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (123
FT                   aa), FASTA scores: opt: 468, E(): 6.7e-23, (66.65% identity
FT                   in 108 aa overlap). Also similar to Q9L1G5|SCC88.24c
FT                   PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (118
FT                   aa), FASTA scores: opt: 130, E(): 0.13, (37.2% identity in
FT                   86 aa overlap); and some similarity to O06852|Y13070
FT                   hypothetical Streptomyces coelicolor gene also between fpgs
FT                   and ndk genes (see citation below) (117 aa), FASTA scores:
FT                   opt: 128, E(): 0.17, (36.0% identity in 86 aa overlap)."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK2"
FT                   /protein_id="CAD97334.1"
FT                   /translation="MTDRSREPADPWKGFSAVMAATLILEAIVVLLAIPVVDAVGGGLR
FT                   PASLGYLVGLAVLLILLTGLQRRPWAIWVNLGAQPVLVAGFAVYPGVGFIGVLFAALWV
FT                   LIAYLRAEVRRRRDYRVSQ"
FT   CDS             complement(203298..204761)
FT                   /transl_table=11
FT                   /gene="folC"
FT                   /locus_tag="Mb2474c"
FT                   /product="PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC
FT                   (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS)"
FT                   /EC_number="6.3.2.17"
FT                   /note="Mb2474c, folC, len: 487 aa. Equivalent to Rv2447c,
FT                   len: 487 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 487 aa overlap). Probable folC,
FT                   folylpolyglutamate synthase (EC 6.3.2.17), equivalent to
FT                   Q9CBY8|FOLC|ML1471 from Mycobacterium leprae (485 aa),
FT                   FASTA scores: opt: 2425, E(): 2.2e-134, (78.7% identity in
FT                   483 aa overlap). Also highly similar to others e.g.
FT                   Q9L1G4|FPGS|O08416|Y13070 from Streptomyces coelicolor (444
FT                   aa), FASTA scores: opt: 774, E(): 6.3e-38, (53.9% identity
FT                   in 462 aa overlap); P15925|FOLC_LACCA|FGS from
FT                   Lactobacillus casei (428 aa), FASTA scores: opt: 631, E():
FT                   1.4e-29, (34.55% identity in 437 aa overlap);
FT                   Q05865|FOLC_BACSU from Bacillus subtilis (430 aa), FASTA
FT                   scores: opt: 421, E(): 2.6e-17, (32.9% identity in 383 aa
FT                   overlap); etc. Contains PS01012 Folylpolyglutamate synthase
FT                   signature 2. BELONGS TO THE FOLYLPOLYGLUTAMATE SYNTHASE
FT                   FAMILY."
FT                   /db_xref="GOA:Q7TYK1"
FT                   /db_xref="HSSP:1FGS"
FT                   /db_xref="InterPro:IPR018109"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK1"
FT                   /protein_id="CAD97335.1"
FT                   /translation="MNSTNSGPPDSGSATGVVPTPDEIASLLQVEHLLDQRWPETRIDP
FT                   SLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVARMVDALVTALHRRTGRTTSPHLQSP
FT                   VERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGKGGPAMSKFEVLTAMAFAAF
FT                   ADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITR
FT                   APDGSPDTVAVIGRQVPKVMEVLLAESVRADASVAREDSEFAVLRRQIAVGGQVLQLQG
FT                   LGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQLDGDAVRAGFAAVTSPGRLE
FT                   RMRSAPTVFIDAAHNPAGASALAQTLAHEFDFRFLVGVLSVLGDKDVDGILAALEPVFD
FT                   SVVVTHNGSPRALDVEALALAAGERFGPDRVRTAENLRDAIDVATSLVDDAAADPDVAG
FT                   DAFSRTGIVITGSVVTAGAARTLFGRDPQ"
FT   CDS             complement(204758..207388)
FT                   /transl_table=11
FT                   /gene="valS"
FT                   /locus_tag="Mb2475c"
FT                   /product="PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS
FT                   (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE
FT                   TRANSLASE)"
FT                   /EC_number="6.1.1.9"
FT                   /note="Mb2475c, valS, len: 876 aa. Equivalent to Rv2448c,
FT                   len: 876 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 876 aa overlap). Probable valS,
FT                   valyl-tRNA synthetases (EC 6.1.1.9), equivalent to
FT                   Q9CBY7|VALS|ML1472 VALYL-TRNA SYNTHASE from Mycobacterium
FT                   leprae (886 aa), FASTA scores: opt: 5181,E(): 0, (85.4%
FT                   identity in 876 aa overlap). Also highly similar to others
FT                   e.g. O06851|SYV_STRCO from Streptomyces coelicolor (874
FT                   aa), FASTA scores: opt: 2470, E(): 1.6e-143, (60.45%
FT                   identity in 880 aa overlap); Q9X2D7|SYV_THEMA|VALS|TM1817
FT                   from Thermotoga maritima (865 aa), FASTA scores: opt: 2418,
FT                   E(): 2.4e-140, (44.2% identity in 891 aa overlap);
FT                   Q05873|SYV_BACSU|VALS from Bacillus subtilis (880 aa),
FT                   FASTA scores: opt: 2063, E(): 1.4e-118, (46.08% identity in
FT                   894 aa overlap); etc. Contains PS00178 Aminoacyl-transfer
FT                   RNA synthetases class-I signature. Contains probable
FT                   coiled-coil from aa 810 to 846. BELONGS TO CLASS-I
FT                   AMINOACYL-TRNA SYNTHETASE FAMILY."
FT                   /db_xref="GOA:P67600"
FT                   /db_xref="HSSP:1IVS"
FT                   /db_xref="InterPro:IPR001412"
FT                   /db_xref="UniProtKB/Swiss-Prot:P67600"
FT                   /protein_id="CAD97336.1"
FT                   /translation="MLPKSWDPAAMESAIYQKWLDAGYFTADPTSTKPAYSIVLPPPNV
FT                   TGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGTDHAGIATQSVVEQQLAVDGKTKED
FT                   LGRELFVDKVWDWKRESGGAIGGQMRRLGDGVDWSRDRFTMDEGLSRAVRTIFKRLYDA
FT                   GLIYRAERLVNWSPVLQTAISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETM
FT                   LGDTAIAVHPDDERYRHLVGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPND
FT                   FEIGVRHQLPMPSILDTKGRIVDTGTRFDGMDRFEARVAVRQALAAQGRVVEEKRPYLH
FT                   SVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVIHPASMEPRWFSWVDDMH
FT                   DWCISRQLWWGHRIPIWYGPDGEQVCVGPDETPPQGWEQDPDVLDTWFSSALWPFSTLG
FT                   WPDKTAELEKFYPTSVLVTGYDILFFWVARMMMFGTFVGDDAAITLDGRRGPQVPFTDV
FT                   FLHGLIRDESGRKMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAVRA
FT                   SRNFGTKLFNATRYALLNGAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAFDGYEFS
FT                   RACESLYHFAWDEFCDWYLELAKTQLAQGLTHTTAVLAAGLDTLLRLLHPVIPFLTEAL
FT                   WLALTGRESLVSADWPEPSGISVDLVAAQRINDMQKLVTEVRRFRSDQGLADRQKVPAR
FT                   MHGVRDSDLSNQVAAVTSLAWLTEPGPDFEPSVSLEVRLGPEMNRTVVVELDTSGTIDV
FT                   AAERRRLEKELAGAQKELASTAAKLANADFLAKAPDAVIAKIRDRQRVAQQETERITTR
FT                   LAALQ"
FT   CDS             complement(207476..208735)
FT                   /transl_table=11
FT                   /gene="Mb2476c"
FT                   /locus_tag="Mb2476c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2476c, -, len: 419 aa. Equivalent to Rv2449c, len:
FT                   419 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 419 aa overlap). Conserved hypothetical
FT                   protein, highly similar to hypothetical proteins e.g.
FT                   P95139|Rv2953|MTCY349.37c from M. tuberculosis (418 aa),
FT                   FASTA scores: opt: 1829, E(): 4.7e-103, (67.3% identity in
FT                   419 aa overlap); AAK47353|MT3027 from Mycobacterium
FT                   tuberculosis strain CDC1551 (418 aa), FASTA score: opt:
FT                   1829, E(): 4.7e-103, (67.3 identity in 419 aa overlap);
FT                   Q9CD87|ML0129 from Mycobacterium leprae (418 aa), FASTA
FT                   scores: opt: 1727, E(): 6.8e-97, (65.45% identity in 414 aa
FT                   overlap); etc."
FT                   /db_xref="GOA:Q7TYK0"
FT                   /db_xref="InterPro:IPR005097"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYK0"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97337.1"
FT                   /translation="MTATPREFDIVLYGATGFVGKLTAEYLARAGGDARIALAGRSTQR
FT                   VLAVREALGESAQTWPILTADASLPSTLQAMAARAQVVVTTVGPYTRYGLPLVAACAAA
FT                   GTDYADLTGEPMFMRNSIDLYHKQAADTGARIVHACGFDSVPSDLSVYALYHAAREDGA
FT                   GELTDTNCVVRSFKGGFSGGTIASMLEVLSTASNDPDARRQLSDPYMLSPDRGAEPELG
FT                   PQPDLPSRRGRRLAPELAGVWTAGFIMAPTNTRIVRRSNALLDWAYGRRFRYSETMSVG
FT                   STVLAPVVSVVGGGVGNAMFGLASRYIRLLPRGLVKRVVPKPGTGPSAAARERGYYRIE
FT                   TYTTTTTGARYLARMAQDGDPGYKATSVLLGECGLALALDRDKLSDMRGVLTPAAAMGD
FT                   ALLERLPAAGVSLQTTRLAS"
FT   CDS             complement(208825..209343)
FT                   /transl_table=11
FT                   /gene="rpfE"
FT                   /locus_tag="Mb2477c"
FT                   /product="PROBABLE RESUSCITATION-PROMOTING FACTOR RPFE"
FT                   /note="Mb2477c, rpfE, len: 172 aa. Equivalent to Rv2450c,
FT                   len: 172 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.4% identity in 172 aa overlap). Probable rpfE,
FT                   resuscitation-promoting factor (see first citation below),
FT                   similar to O86308|Z96935|MLRPF_1 RPF PROTEIN PRECURSOR from
FT                   Micrococcus luteus (220 aa), FASTA scores: opt: 291, E():
FT                   3e-7, (48.75% identity in 80 aa overlap). C-terminus is
FT                   similar to other Mycobacterial rpf proteins e.g.
FT                   O05594|Rv1009|MTCI237.26|RPFB PROBABLE
FT                   RESUSCITATION-PROMOTING FACTOR from Mycobacterium
FT                   tuberculosis (362 aa), FASTA scores: opt: 344, E():
FT                   1.4e-09, (42.85% identity in 147 aa overlap); etc.
FT                   C-terminal region similar to N-terminal region of
FT                   Q9F2Q2|SCE41.06c PUTATIVE SECRETED PROTEIN from
FT                   Streptomyces coelicolor (244 aa), FASTA scores: opt: 355,
FT                   E(): 3.1e-10, (56.65% identity in 90 aa overlap). Also
FT                   similar to Q9F2Q1|SCE41.07c PUTATIVE SECRETED PROTEIN from
FT                   Streptomyces coelicolor (near Q9F2Q2|SCE41.06c) (341 aa)
FT                   FASTA scores: opt: 317, E(): 2.5e-08, (51.7% identity in 87
FT                   aa overlap). With Mycobacterium leprae, high similarity
FT                   between the two corresponding C-terminal regions of two
FT                   HYPOTHETICAL PROTEINS, Q9CD53|ML0240 (375 aa), FASTA
FT                   scores: opt: 339, E(): 2.5e-09, (59.15% identity in 93 aa
FT                   overlap) and O33049|MLCB57.05c|ML2151 (174 aa), FASTA
FT                   scores: opt: 329, E(): 4e-09, (58.14% identity in 86 aa
FT                   overlap). Contains a possible secretory signal sequence in
FT                   N-terminus. Possible autocrine and/or paracrine bacterial
FT                   growth factor or cytokine (see citation below)."
FT                   /db_xref="GOA:Q7TYJ9"
FT                   /db_xref="InterPro:IPR010618"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97338.1"
FT                   /translation="MKNARTTLIAAAIAGTLVTTSPAGIANADDAGLDPNAAAGPDAVG
FT                   FDPNLPPAPDAAPVDTPPAPEDAGFDPNLPPPLAPDFLSPPAEEAPPVPVAYSVNWDAI
FT                   AQCESGGNWSINTGNGYYGGLQFTAGTWRANGGSGSAANASREEQIRVAENVLRSQGIR
FT                   AWPVCGRRG"
FT   CDS             209425..209823
FT                   /transl_table=11
FT                   /gene="Mb2478"
FT                   /locus_tag="Mb2478"
FT                   /product="HYPOTHETICAL PROLINE AND SERINE RICH PROTEIN"
FT                   /note="Mb2478, -, len: 132 aa. Equivalent to Rv2451, len:
FT                   132 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.2% identity in 132 aa overlap). Hypothetical unknown
FT                   pro-, ser-rich protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ8"
FT                   /protein_id="CAD97339.1"
FT                   /translation="MGRAVSVRHGSGALDLPGAAASRRLRVGQPIQPSPAPLARGSVDS
FT                   IVEISCCPSAGPRGPYDDDLDSSSPANRDISSITSRSRRGGTIVVAGQKCGFGSAVSLR
FT                   PRRYREPNHANIVTPDTDLSPSWPWSGI"
FT   CDS             complement(210011..210157)
FT                   /transl_table=11
FT                   /gene="Mb2479c"
FT                   /locus_tag="Mb2479c"
FT                   /product="HYPOTHETICAL PROTEIN"
FT                   /note="Mb2479c, -, len: 48 aa. Equivalent to Rv2452c, len:
FT                   48 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 48 aa overlap). Hypothetical unknown
FT                   protein."
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ7"
FT                   /protein_id="CAD97340.1"
FT                   /translation="MAFRDILVLFSMKTLLTLAMAAASSTALTTVGVSGARLITYCVGV
FT                   EDI"
FT   CDS             complement(210181..210786)
FT                   /transl_table=11
FT                   /gene="mobA"
FT                   /locus_tag="Mb2480c"
FT                   /product="PROBABLE MOLYBDOPTERIN-GUANINE DINUCLEOTIDE
FT                   BIOSYNTHESIS PROTEIN A MOBA"
FT                   /note="Mb2480c, mobA, len: 201 aa. Equivalent to Rv2453c,
FT                   len: 201 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 201 aa overlap). Probable mobA,
FT                   molybdopterin-guanine dinucleotide biosynthesis protein A,
FT                   similar to others e.g. Q9F8G7 from Carboxydothermus
FT                   hydrogenoformans (224 aa), FASTA scores: opt: 249, E():
FT                   3.9e-08, (30.6% identity in 173 aa overlap);
FT                   P95645|MOBA_RHOSH|MOB|Y09560 from Rhodobacter sphaeroides
FT                   (199 aa), FASTA scores: opt: 240, E(): 1.2e-07, (33.9%
FT                   identity in 186 aa overlap); Q9X7K0|MOBA_RHOCA from
FT                   Rhodobacter capsulatus (Rhodopseudomonas capsulata) (191
FT                   aa), FASTA scores: opt: 217, E(): 2.9e-06, (37.4% identity
FT                   in 123 aa overlap); etc. BELONGS TO THE MOBA FAMILY."
FT                   /db_xref="GOA:P65403"
FT                   /db_xref="HSSP:1E5K"
FT                   /db_xref="UniProtKB/Swiss-Prot:P65403"
FT                   /protein_id="CAD97341.1"
FT                   /translation="MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGTTTLVEHMV
FT                   GILGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAGVRLAFVC
FT                   AVDMPYLTVELIEDLARRAVQTDAEVVLPWDGRNHYLAAVYRTDLADRVDTLVGAGERK
FT                   MSALVDASDALRIVMADSRPLTNVNSAAGLHAPMQPGR"
FT   CDS             complement(210788..211909)
FT                   /transl_table=11
FT                   /gene="Mb2481c"
FT                   /locus_tag="Mb2481c"
FT                   /product="PROBABLE OXIDOREDUCTASE (BETA SUBUNIT)"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2481c, -, len: 373 aa. Equivalent to Rv2454c, len:
FT                   373 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 373 aa overlap). Probable
FT                   oxidoreductase, beta subunit (EC 1.-.-.-), similar to
FT                   Q9F2W7|SCD20.12c PUTATIVE OXIDOREDUCTASE from Streptomyces
FT                   coelicolor (352 aa), FASTA scores: opt: 1461, E(): 6.4e-85,
FT                   (65.3% identity in 343 aa overlap) alias Q9RKS5|STAH10.34c
FT                   PUTATIVE OXIDOREDUCTASE BETA-SUBUNIT from Streptomyces
FT                   coelicolor (350 aa), FASTA scores: opt: 1429, E(): 6.7e-83,
FT                   (64.0% identity in 342 aa overlap); and similar in part to
FT                   others e.g. Q9Z5X3 FERREDOXIN OXIDOREDUCTASE B-SUBUNIT from
FT                   Frankia sp. (346 aa), FASTA scores: opt: 1143, E():
FT                   7.5e-65, (51.2% identity in 336 aa overlap); BAB21495|KORB
FT                   FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT from Hydrogenobacter
FT                   thermophilus TK-6 (295 aa), FASTA scores: opt: 682, E():
FT                   8.3e-36, (48.25% identity in 201 aa overlap); etc. Note
FT                   that the upstream ORF (MTV008.11c|Rv2455c) is possibly an
FT                   oxidoreductase alpha subunit."
FT                   /db_xref="GOA:Q7TYJ6"
FT                   /db_xref="InterPro:IPR011766"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ6"
FT                   /protein_id="CAD97342.1"
FT                   /translation="MTRSGDEAQLMTGVTGDLAGTELGLTPSLTKNAGVPTTDQPQKGK
FT                   DFTSDQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLETYGFH
FT                   SIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRRNINVTILLFNNRIY
FT                   GLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLR
FT                   AAAQHRGAALVEILQDCPIFNDGSFDALRKEGAEERVIKVRHGEPIVFGANGEYCVVKS
FT                   GFGLEVAKTADVAIDEIIVHDAQVDDPAYAFALSRLSDQNLDHTVLGIFRHISRPTYDD
FT                   AARSQVVAARNAAPSGTAALQSLLHGRDTWTVD"
FT   CDS             complement(211906..213867)
FT                   /transl_table=11
FT                   /gene="Mb2482c"
FT                   /locus_tag="Mb2482c"
FT                   /product="PROBABLE OXIDOREDUCTASE (ALPHA SUBUNIT)"
FT                   /EC_number="1.-.-.-"
FT                   /note="Mb2482c, -, len: 653 aa. Equivalent to Rv2455c, len:
FT                   653 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 653 aa overlap). Probable
FT                   oxidoreductase, alpha subunit (EC 1.-.-.-), similar to
FT                   others e.g. Q9F2W6|SCD20.13c PUTATIVE OXIDOREDUCTASE from
FT                   Streptomyces coelicolor (645 aa), FASTA scores: opt: 2017,
FT                   E(): 1e-111, (66.45% identity in 617 aa overlap) alias
FT                   Q9RKS4|STAH10.35c PUTATIVE OXIDOREDUCTASE ALPHA-SUBUNIT
FT                   from Streptomyces coelicolor (630 aa), FASTA scores: opt:
FT                   2008, E(): 3.4e-111, (66.45% identity in 614 aa overlap);
FT                   Q9YA13|APE2126 LONG HYPOTHETICAL 2-OXOACID--FERREDOXIN
FT                   OXIDOREDUCTASE ALPHA CHAIN from Aeropyrum pernix (644 aa)
FT                   FASTA scores: opt: 687, E(): 4.6e-33, (33.35% identity in
FT                   441 aa overlap); etc. Note that the downstream ORF
FT                   (MTV008.10c|Rv2454c) is possibly an oxidoreductase beta
FT                   subunit."
FT                   /db_xref="GOA:Q7TYJ5"
FT                   /db_xref="InterPro:IPR002880"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ5"
FT                   /protein_id="CAD97343.1"
FT                   /translation="MDPNGSGAGPESHDAAFHAAPDRQRLENVVIRFAGDSGDGMQLTG
FT                   DRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDILTAGDRPDVLVAM
FT                   NPAALKANIGDLPLGGMVIVNSDEFTKRNLTKVGYVTNPLESGELSDYVVHTVAMTTLT
FT                   LGAVEAIGASKKDGQRAKNMFALGLLSWMYGRELEHSEAFIREKFARKPEIAEANVLAL
FT                   KAGWNYGETTEAFGTTYEIPPATLPPGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYP
FT                   ITPASDILHELSKHKNFNVVTFQAEDEIGGICAALGAAYGGALGVTSTSGPGISLKSEA
FT                   LGLGVMTELPLLVIDVQRGGPSTGLPTKTEQADLLQALYGRNGESPVAVLAPRSPADCF
FT                   ETALEAVRIAVSYHTPVILLSDGAIANGSEPWRIPDVNALPPIKHTFAKPGEPFQPYAR
FT                   DRETLARQFAIPGTPGLEHRIGGLEAANGSGDISYEPTNHDLMVRLRQAKIDGIHVPDL
FT                   EVDDPTGDAELLLIGWGSSYGPIGEACRRARRRGTKVAHAHLRYLNPFPANLGEVLRRY
FT                   PKVVAPELNLGQLAQVLRGKYLVDVQSVTKVKGVSFLADEIGRFIRAALAGRLAELEQD
FT                   KTLVARLSAATAGAGANG"
FT   CDS             complement(214099..215355)
FT                   /transl_table=11
FT                   /gene="Mb2483c"
FT                   /locus_tag="Mb2483c"
FT                   /product="PUTATIVE CONSERVED INTEGRAL MEMBRANE TRANSPORT
FT                   PROTEIN"
FT                   /note="Mb2483c, -, len: 418 aa. Equivalent to Rv2456c, len:
FT                   418 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 418 aa overlap). Probable conserved
FT                   integral membrane transport protein, involved in a efflux
FT                   system, weakly similar to many e.g.
FT                   Q9RUR0|YD22_DEIRA|DR1322 PUTATIVE SUGAR EFFLUX TRANSPORTER
FT                   from Deinococcus radiodurans (389 aa), FASTA scores: opt:
FT                   224, E(): 8.4e-06, (24.45% identity in 409 aa overlap);
FT                   Q9UYY0|PAB0913 MULTIDRUG RESISTANCE PROTEIN from Pyrococcus
FT                   abyssi (410 aa), FASTA scores: opt: 210, E(): 5.6e-05,
FT                   (21.8% identity in 408 aa overlap); etc. Contains PS00216
FT                   Sugar transport proteins signature 1."
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ4"
FT                   /protein_id="CAD97344.1"
FT                   /translation="MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWD
FT                   QASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRALVVAGAVLVTAAAVAMPLFAGLYSI
FT                   SVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYF
FT                   FGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRE
FT                   LVIFGAAVVAFHFANAAMLPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTR
FT                   ADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLLDGIGAGIFGALFPLVVQDVT
FT                   HGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAM
FT                   PETVDSDVRVRSRPTLGGK"
FT   CDS             complement(215371..216651)
FT                   /transl_table=11
FT                   /gene="clpX"
FT                   /locus_tag="Mb2484c"
FT                   /product="PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING
FT                   SUBUNIT CLPX"
FT                   /EC_number="3.4.-.-"
FT                   /note="Mb2484c, clpX, len: 426 aa. Equivalent to Rv2457c,
FT                   len: 426 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 426 aa overlap). Probable clpX,
FT                   ATP-dependent clp protease ATP-binding subunit clpX (EC
FT                   3.4.-.-), equivalent to Q9CBY6|CLPX|ML1477 ATP-DEPENDENT
FT                   CLP PROTEASE ATP-BINDING PROTEIN from Mycobacterium leprae
FT                   (426 aa), FASTA scores: opt: 2652, E(): 1.4e-142, (96.0%
FT                   identity in 426 aa overlap). Also highly similar to others
FT                   e.g. Q9F316|CLPX from Streptomyces coelicolor (428 aa)
FT                   FASTA scores: opt: 2178, E(): 8.2e-116, (77.8% identity in
FT                   428 aa overlap); P50866|CLPX_BACSU from Bacillus subtilis
FT                   (420 aa), FASTA scores: opt: 1788, E(): 8.5e-94, (63.6%
FT                   identity in 426 aa overlap); P33138|CLPX_ECOLI from
FT                   Escherichia coli (423 aa), FASTA scores: opt: 1694, E():
FT                   1.7e-88, (62.4% identity in 415 aa overlap); etc. Contains
FT                   PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO
FT                   THE CLPX CHAPERONE FAMILY."
FT                   /db_xref="GOA:P0A529"
FT                   /db_xref="HSSP:1OFI"
FT                   /db_xref="InterPro:IPR010603"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A529"
FT                   /protein_id="CAD97345.1"
FT                   /translation="MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEI
FT                   IEEELADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRD
FT                   SRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENI
FT                   LLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQA
FT                   SVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEI
FT                   DTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRL
FT                   FEMDGVELEFTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
FT                   KETVQDNVLPTIVPRKPSRSERRDKSA"
FT   CDS             216942..217850
FT                   /transl_table=11
FT                   /gene="mmuM"
FT                   /locus_tag="Mb2485"
FT                   /product="PROBABLE HOMOCYSTEINE S-METHYLTRANSFERASE MMUM
FT                   (S-METHYLMETHIONINE:HOMOCYSTEINE METHYLTRANSFERASE)
FT                   (CYSTEINE METHYLTRANSFERASE)"
FT                   /EC_number="2.1.1.10"
FT                   /note="Mb2485, mmuM, len: 302 aa. Equivalent to Rv2458,
FT                   len: 302 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.7% identity in 302 aa overlap). Probable mmuM,
FT                   homocysteine S-methyltransferase (EC 2.1.1.10), equivalent
FT                   to Q9CBY5|ML1478 POSSIBLE TRANSFERASE from Mycobacterium
FT                   leprae (293 aa), FASTA scores: opt: 1507, E(): 2.7e-86,
FT                   (78.85% identity in 293 aa overlap). Also similar to others
FT                   e.g. Q47690|MMUM_ECOLI|B0261 HOMOCYSTEINE
FT                   S-METHYLTRANSFERASE from Escherichia coli strain K12 (310
FT                   aa), FASTA scores: opt: 863, E(): 2.4e-46, (47.65% identity
FT                   in 298 aa overlap); Q9FUM7 HOMOCYSTEINE
FT                   S-METHYLTRANSFERASE-4 from Zea mays (Maize) (342 aa), FASTA
FT                   scores: opt: 324, E(): 6.8e-13, (44.45% identity in 306 aa
FT                   overlap); Q9LUI7|HMT3 CYSTEINE METHYLTRANSFERASE from
FT                   Arabidopsis thaliana (Mouse-ear cress) (347 aa), FASTA
FT                   scores: opt: 312, E(): 3.8e-12, (41.85% identity in 313 aa
FT                   overlap); etc. Identical to AAK46833|MT2533 HOMOCYSTEINE
FT                   S-METHYLTRANSFERASE from Mycobacterium tuberculosis strain
FT                   CDC1551 (302 aa)."
FT                   /db_xref="GOA:Q7TYJ3"
FT                   /db_xref="InterPro:IPR003726"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ3"
FT                   /protein_id="CAD97346.1"
FT                   /translation="MELVSDSVLISDGGLATELEARGHDLSDPLWSARLLVDAPHAITA
FT                   VHTAYFRAGAQIATTASYQASFEGFAARGIGHDDATVLLRRSVELAQAARDEVGVGGLS
FT                   VAASVGPYGAALADGSEYRGCYGLSVAALMKWHLPRLEVLVDAGADMLALETIPDIDEA
FT                   EALVNLVRRLATPAWLSYTINGTRTRAGQPLTDAFAVAAGVPEIVAVGVNCCAPDDVLP
FT                   AIAFAVAHTGKPVIVYPNSGEGWDGRRRAWVGPRRFSGSSGQLAREWVAAGARIVGGCC
FT                   RVRPIDIAEIGRALTTAPPRG"
FT   CDS             218017..219543
FT                   /transl_table=11
FT                   /gene="Mb2486"
FT                   /locus_tag="Mb2486"
FT                   /product="PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT
FT                   PROTEIN"
FT                   /note="Mb2486, -, len: 508 aa. Equivalent to Rv2459, len:
FT                   508 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 508 aa overlap). Probable conserved
FT                   integral membrane transport protein, member of major
FT                   facilitator superfamily (MFS) possibly involved in drug
FT                   transport, highly similar to many efflux proteins e.g.
FT                   Q9RL22|SC5G9.04c PUTATIVE TRANSMEMBRANE EFFLUX PROTEIN from
FT                   Streptomyces coelicolor (489 aa), FASTA scores: opt: 788,
FT                   E(): 1.3e-38, (34.45% identity in 412 aa overlap);
FT                   Q9I428|PA1316 PROBABLE MFS TRANSPORTER from Pseudomonas
FT                   aeruginosa (513 aa), FASTA scores: opt: 782, E(): 3.1e-38,
FT                   (32.75% identity in 519 aa overlap); P39886|TCMA_STRGA
FT                   tetracenomycin C resistance and export protein from
FT                   Streptomyces glaucescens (538 aa), FASTA scores: opt: 752,
FT                   E(): 1.8e-36, (31.7% identity in 511 aa overlap); etc. Also
FT                   highly similar to AAK46687|MT2395 DRUG TRANSPORTER from
FT                   Mycobacterium tuberculosis strain CDC1551 (537 aa), FASTA
FT                   scores: opt: 1396, E(): 5.6e-74, (44.45% identity in 504 aa
FT                   overlap); and P71879|Rv2333c|MTCY3G12.01 PROBABLE CONSERVED
FT                   INTEGRAL MEMBRANE TRANSPORT PROTEIN from Mycobacterium
FT                   tuberculosis strain H37Rv (537 aa), FASTA scores: opt:
FT                   1385, E(): 2.5e-73, (44.25% identity in 504 aa overlap)."
FT                   /db_xref="InterPro:IPR011701"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ2"
FT                   /protein_id="CAD97347.1"
FT                   /translation="MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQ
FT                   WAVAGYSLGIAAVLMSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVI
FT                   QGLGAAFISVLSLALLSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRS
FT                   VFLVNVPLGAIVWLLTLVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQ
FT                   SAGFVAALLLAAGVLLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTL
FT                   MVITQHFQNVRDLSPLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIG
FT                   LAIFAISMDHAHPVALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSL
FT                   GGIFGVAFLGTIVAAWLGAALPNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGH
FT                   RITAAQEDEIVLAADAVFVSGIKLALGGAAVLLTGAFVLGWTRFPRTPAS"
FT   CDS             complement(219694..220338)
FT                   /transl_table=11
FT                   /gene="clpP2"
FT                   /locus_tag="Mb2487c"
FT                   /product="PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC
FT                   SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)"
FT                   /EC_number="3.4.21.92"
FT                   /note="Mb2487c, clpP2, len: 214 aa. Equivalent to Rv2460c,
FT                   len: 214 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 214 aa overlap). Probable clpP2,
FT                   ATP-dependent clp protease proteolytic subunit 2 (EC
FT                   3.4.21.92), equivalent to Q9CBY4|CLP2_MYCLE ATP-DEPENDENT
FT                   CLP PROTEASE PROTEOLYTIC SUBUNIT from Mycobacterium leprae
FT                   (214 aa). Also highly similar to others e.g. Q9ZH58|CLPP2
FT                   from Streptomyces coelicolor (236 aa), FASTA scores: opt:
FT                   918, E(): 2.1e-50, (66.35% identity in 214 aa overlap);
FT                   O67357|CLPP_AQUAE|AQ_1339 from Aquifex aeolicus (201 aa),
FT                   FASTA scores: opt: 680, E(): 1.4e-35, (52.0% identity in
FT                   194 aa overlap); P43867|CLPP_HAEIN from Haemophilus
FT                   influenzae (193 aa), FASTA scores: opt: 662, E(): 1.8e-34,
FT                   (53.35% identity in 193 aa overlap); etc. Contains PS00381
FT                   Endopeptidase Clp serine active site. Also similar to
FT                   upstream ORF Rv2461c|MTV008.17c|clpP1 (200 aa), FASTA
FT                   score: (48.3% identity in 172 aa overlap). BELONGS TO
FT                   PEPTIDASE FAMILY S14, ALSO KNOWN AS CLPP FAMILY."
FT                   /db_xref="GOA:P63784"
FT                   /db_xref="HSSP:1TYF"
FT                   /db_xref="InterPro:IPR018215"
FT                   /db_xref="UniProtKB/Swiss-Prot:P63784"
FT                   /protein_id="CAD97348.1"
FT                   /translation="MNSQNSQIQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFLG
FT                   VQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVC
FT                   LGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTL
FT                   METTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQTA"
FT   CDS             complement(220335..220937)
FT                   /transl_table=11
FT                   /gene="clpP1"
FT                   /locus_tag="Mb2488c"
FT                   /product="PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC
FT                   SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)"
FT                   /EC_number="3.4.21.92"
FT                   /note="Mb2488c, clpP1, len: 200 aa. Equivalent to Rv2461c,
FT                   len: 200 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 200 aa overlap). Probable clpP1,
FT                   ATP-dependent clp protease proteolytic subunit 1 (EC
FT                   3.4.21.92), equivalent to Q9CBY3|CLP1_MYCLE ATP-DEPENDENT
FT                   CLP PROTEASE PROTEOLYTIC SUBUNIT from Mycobacterium leprae
FT                   (224 aa), FASTA scores: opt: 1226, E(): 1.3e-71, (95.0%
FT                   identity in 200 aa overlap). Also highly similar to others
FT                   e.g. Q9F315|CLPP1 from Streptomyces coelicolor (219 aa),
FT                   FASTA scores: opt: 713, E(): 9.3e-39, (61.75% identity in
FT                   183 aa overlap); P80244|CLPP_BACSU from Bacillus subtilis
FT                   (197 aa), FASTA scores: opt: 658, E(): 2.8e-35, (54%
FT                   identity in 187 aa overlap); Q9WZF9|CLPP_THEMA|TM0695 from
FT                   Thermotoga maritima (203 aa), FASTA scores: opt: 653, E():
FT                   6.1e-35, (55.25% identity in 172 aa overlap); etc. Also
FT                   similar to downstream ORF Rv2460c|MTV008.16c|clpP2 (214
FT                   aa), FASTA score: (48.3% identity in 172 aa overlap).
FT                   BELONGS TO PEPTIDASE FAMILY S14, ALSO KNOWN AS CLPP FAMILY.
FT                   Note that previously known as clp."
FT                   /db_xref="GOA:P0A527"
FT                   /db_xref="HSSP:1TYF"
FT                   /db_xref="InterPro:IPR018215"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0A527"
FT                   /protein_id="CAD97349.1"
FT                   /translation="MSQVTDMRSNSQGLSLTDSVYERLLSERIIFLGSEVNDEIANRLC
FT                   AQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLL
FT                   AAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIE
FT                   RIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGEAQ"
FT   CDS             complement(221054..222454)
FT                   /transl_table=11
FT                   /gene="tig"
FT                   /locus_tag="Mb2489c"
FT                   /product="PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG"
FT                   /note="Mb2489c, tig, len: 466 aa. Equivalent to Rv2462c,
FT                   len: 466 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (99.8% identity in 466 aa overlap). Probable tig, trigger
FT                   factor (TF), a chaperone protein, equivalent to
FT                   Q9CBY2|ML1481 POSSIBLE MOLECULAR CHAPERONE from
FT                   Mycobacterium leprae (469 aa), FASTA scores: opt: 2171,
FT                   E(): 7.2e-113, (70.1% identity in 468 aa overlap). Also
FT                   similar to oyher trigger factors from several organisms
FT                   e.g. Q9F314|SCC80.05c from Streptomyces coelicolor (468
FT                   aa), FASTA scores: opt: 1224, E(): 1.7e-60, (41.8% identity
FT                   in 469 aa overlap); Q9K8F3|TIG_BACHD from Bacillus
FT                   halodurans (431 aa), FASTA scores: opt: 675, E(): 3.6e-30,
FT                   (28.5% identity in 421 aa overlap); P22257|TIG_ECOLI from
FT                   Escherichia coli (432 aa), FASTA scores: opt: 493, E():
FT                   4.2e-20, (23.35% identity in 433 aa overlap); etc. BELONGS
FT                   TO THE FKBP-TYPE PPIASE FAMILY, TIG SUBFAMILY."
FT                   /db_xref="GOA:Q7TYJ1"
FT                   /db_xref="InterPro:IPR008881"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYJ1"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97350.1"
FT                   /translation="MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFR
FT                   PGKAPAKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEYGQDL
FT                   QFTAEVDIRPKISLPDLSALTVSVDPIEIGEDDVDAELQSLRTRFGTLTAVDRPVAVGD
FT                   VVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLDDAVVGLSADESRVFTAKLAAGE
FT                   HAGQEAQVTVTVRSVKERELPEPDDEFAQLASEFDSIDELRASLSDQVRQAKRAQQAEQ
FT                   IRNATIDALLEQVDVPLPESYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFD
FT                   AEARTASEKDVKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERN
FT                   QLPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKRVSAGEAEEAEPADEGAAR
FT                   AASDEATT"
FT   tRNA            complement(222494..222567)
FT                   /gene="proU"
FT                   /locus_tag="proU"
FT                   /note="proU, len: 74 nt. Equivalent to proU, len: 74 nt,
FT                   from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 74 nt overlap). tRNA-Pro; anticodon tgg."
FT   tRNA            222704..222774
FT                   /gene="glyV"
FT                   /locus_tag="glyV"
FT                   /note="glyV, len: 71 nt. Equivalent to glyV, len: 71 nt,
FT                   from Mycobacterium tuberculosis strain H37Rv, (100.0%
FT                   identity in 71 nt overlap). tRNA-Gly; anticodon tcc."
FT   CDS             222818..224002
FT                   /transl_table=11
FT                   /gene="lipP"
FT                   /locus_tag="Mb2490"
FT                   /product="PROBABLE ESTERASE/LIPASE LIPP"
FT                   /EC_number="3.1.-.-"
FT                   /note="Mb2490, lipP, len: 394 aa. Equivalent to Rv2463,
FT                   len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 394 aa overlap). Probable lipP,
FT                   esterase (EC 3.1.-.-), lipase similar to others eg
FT                   O87861|ESTA ESTERASE A from Streptomyces chrysomallus (389
FT                   aa), FASTA scores: opt: 964, E(): 1.9e-53, (44.35% identity
FT                   in 399 aa overlap); Q9I4S7|PA1047 PROBABLE ESTERASE from
FT                   Pseudomonas aeruginosa (392 aa), FASTA scores: opt: 863,
FT                   E(): 4.6e-47, (40.05% identity in 377 aa overlap);
FT                   Q53403|ESTC ESTERASE III from Pseudomonas fluorescens (382
FT                   aa), FASTA scores: opt: 753, E(): 3.9e-40, (36.3% identity
FT                   in 380 aa overlap); etc."
FT                   /db_xref="GOA:Q7TYJ0"
FT                   /db_xref="InterPro:IPR001466"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYJ0"
FT                   /protein_id="CAD97351.1"
FT                   /translation="MNQPDIKGSCASEFTKVRDAFERNFVLRNEVGAAVAVWVDGDLVV
FT                   NLWGGSADAGGTRPWQHDTLATVLSGTKALTATCVHQLVDRGELDLHAPVARYWPEFGQ
FT                   AGKQAITLAMVMSHRSGAIGPRGRLGWEQVADWDFVCEQLAAAEPWWQPGAAQGYHMTT
FT                   FGFILGEVFRRVTGRTVGQYLRTEIAEPLGADVHIGLHPGEQLRCADLVDKPHIRQLLA
FT                   DVQAPGYPTSLNEHPKAALSVSMGFAPDDELGSNDLQLWRQIEFPGTNGQVSALGLATF
FT                   YNGLAQEKLLSREHMELVRVSQGGFDTDLVLGPRVADHGWGLGYMLNQRGVNGPNPRIF
FT                   GHGGLGGSFGFVDLEHRIGYAYVMNRFDATKANADPRSVVLSNEVYAALGVNRS"
FT   CDS             complement(224022..224828)
FT                   /transl_table=11
FT                   /gene="Mb2491c"
FT                   /locus_tag="Mb2491c"
FT                   /product="POSSIBLE DNA GLYCOSYLASE"
FT                   /EC_number="3.2.2.-"
FT                   /note="Mb2491c, -, len: 268 aa. Equivalent to Rv2464c, len:
FT                   268 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 268 aa overlap). Possible DNA
FT                   glycosylase (EC 3.2.2.-), showing some similarity to
FT                   several other DNA glycosylases e.g. Q9F308|SCC80.11c
FT                   PUTATIVE DNA REPAIR HYDROLASE (FRAGMENT) from Streptomyces
FT                   coelicolor (306 aa), FASTA scores: opt: 894, E(): 6.1e-51,
FT                   (51.05% identity in 282 aa overlap); O50606|MUTM|FPG_THETH
FT                   FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (EC 3.2.2.23) from
FT                   Thermus aquaticus (267 aa), FASTA scores: opt: 342, E():
FT                   4.6e-15, (32.4% identity in 250 aa overlap);
FT                   Q9RCW5|SCM10.34c PUTATIVE FORMAMIDOPYRIMIDINE-DNA
FT                   GLYCOSYLASE from Streptomyces coelicolor (287 aa), FASTA
FT                   scores: opt: 321, E(): 1.1e-13, (29.35% identity in 259 aa
FT                   overlap); etc. Identical to AAK46839|MT2539
FT                   FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE from Mycobacterium
FT                   tuberculosis strain CDC1551. Also similar to other M.
FT                   tuberculosis DNA glycosylases e.g. MTCY71.37 (32.9%
FT                   identity in 277 aa overlap). BELONGS TO THE FPG FAMILY."
FT                   /db_xref="GOA:P64159"
FT                   /db_xref="HSSP:1K82"
FT                   /db_xref="InterPro:IPR012319"
FT                   /db_xref="UniProtKB/Swiss-Prot:P64159"
FT                   /protein_id="CAD97352.1"
FT                   /translation="MPEGHTLHRLARLHQRRFAGAPVSVSSPQGRFADSASALNGRVLR
FT                   RASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQVRMRMVGAEFGTD
FT                   LRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLMDQTVIAG
FT                   VGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHG
FT                   LPSYLPDRPRTYVYRRAGEPCRVCGGVIRTALLEGRNVFWCPVCQT"
FT   CDS             complement(224834..225322)
FT                   /transl_table=11
FT                   /gene="Mb2492c"
FT                   /locus_tag="Mb2492c"
FT                   /product="PROBABLE ISOMERASE"
FT                   /EC_number="5.-.-.-"
FT                   /note="Mb2492c, -, len: 162 aa. Equivalent to Rv2465c, len:
FT                   162 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 162 aa overlap). Probable isomerase (EC
FT                   5.-.-.-), equivalent to AAK46840|MT2540 PUTATIVE
FT                   CARBOHYDRATE-PHOSPHATE ISOMERASE from Mycobacterium
FT                   tuberculosis strain CDC1551 (159 aa). Equivalent to
FT                   Q9CBY1|ML1484 POSSIBLE PHOSPHOPENTOSE ISOMERASE from M.
FT                   leprae (162 aa), FASTA scores: opt: 992, E(): 7.1e-59,
FT                   (89.5% identity in 162 aa overlap). Also highly similar or
FT                   similar to several diverse isomerases e.g. Q9L206|SC8E4.02c
FT                   PUTATIVE ISOMERASE from Streptomyces coelicolor (159 aa),
FT                   FASTA scores: opt: 661, E(): 6.1e-37, (61.45% identity in
FT                   153 aa overlap); P47636|Y396_MYCGE|MG396 HYPOTHETICAL
FT                   LACA/RPIB FAMILY PROTEIN from Mycoplasma genitalium (152
FT                   aa), FASTA scores: opt: 357, E(): 8.2e-17, (42% identity in
FT                   150 aa overlap); P53527|Y396_MYCPN|MPN595|MP247
FT                   HYPOTHETICAL LACA/RPIB FAMILY PROTEIN from Mycoplasma
FT                   pneumoniae (152 aa), FASTA scores: opt: 340, E(): 1.1e-15,
FT                   (38.6% identity in 145 aa overlap); P26592|LACB_STAAU
FT                   galactose-6-phosphate isomerase from Staphylococcus aureus
FT                   (171 aa), FASTA scores: opt: 296, E(): 1e-12, (35.4%
FT                   identity in 158 aa overlap) and P37351|RPIB_ECOLI ribose
FT                   5-phosphate isomerase b from Escherichia coli (149 aa),
FT                   FASTA scores: opt: 262, E(): 1.6e-10, (32.2% identity in
FT                   146 aa overlap); etc. COULD BELONG TO THE LACA/RPIB
FT                   FAMILY."
FT                   /db_xref="GOA:Q7TYI9"
FT                   /db_xref="HSSP:1O1X"
FT                   /db_xref="InterPro:IPR003500"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q7TYI9"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT                   /protein_id="CAD97353.1"
FT                   /translation="MSGMRVYLGADHAGYELKQRIIEHLKQTGHEPIDCGALRYDADDD
FT                   YPAFCIAAATRTVADPGSLGIVLGGSGNGEQIAANKVPGARCALAWSVQTAALAREHNN
FT                   AQLIGIGGRMHTVAEALAIVDAFVTTPWSKAQRHQRRIDILAEYERTHEAPPVPGAPA"
FT   CDS             complement(225424..226047)
FT                   /transl_table=11
FT                   /gene="Mb2493c"
FT                   /locus_tag="Mb2493c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2493c, -, len: 207 aa. Equivalent to Rv2466c, len:
FT                   207 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 207 aa overlap). Conserved hypothetical
FT                   protein, equivalent to Q9CBY0|ML1485 HYPOTHETICAL PROTEIN
FT                   from Mycobacterium leprae (207 aa), FASTA scores: opt:
FT                   1154, E(): 1.1e-67, (80.6% identity in 206 aa overlap).
FT                   Also highly similar to Q9L201|SC8E4A.04c HYPOTHETICAL
FT                   PROTEIN from Streptomyces coelicolor (216 aa), FASTA
FT                   scores: opt: 789, E(): 4.6e-44, (57.9% identity in 213 aa
FT                   overlap). Also similar to AAK46628|MT2344 HYPOTHETICAL
FT                   PROTEIN from Mycobacterium tuberculosis strain CDC1551 (230
FT                   aa), FASTA scores: opt: 324, E(): 6.1e-14, (30.4% identity
FT                   in 194 aa overlap). Contains PS00195 Glutaredoxin active
FT                   site."
FT                   /db_xref="GOA:Q7TYI8"
FT                   /db_xref="InterPro:IPR001853"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYI8"
FT                   /protein_id="CAD97354.1"
FT                   /translation="MLEKAPQKSVADFWFDPLCPWCWITSRWILEVAKVRDIEVNFHVM
FT                   SLAILNENRDDLPEQYREGMARAWGPVRVAIAAEQAHGAKVLDPLYTAMGNRIHNQGNH
FT                   ELDEVITQSLADAGLPAELAKAATSDAYDNALRKSHHAGMDAVGEDVGTPTIHVNGVAF
FT                   FGPVLSKIPRGEEAGKLWDASVTFASYPHFFELKRTRTEPPQFD"
FT   CDS             226149..228734
FT                   /transl_table=11
FT                   /gene="pepN"
FT                   /locus_tag="Mb2494"
FT                   /product="PROBABLE AMINOPEPTIDASE N PEPN (LYSYL
FT                   AMINOPEPTIDASE) (LYS-AP) (ALANINE AMINOPEPTIDASE)"
FT                   /EC_number="3.4.11.2"
FT                   /note="Mb2494, pepN, len: 861 aa. Equivalent to Rv2467,
FT                   len: 861 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 861 aa overlap). Probable pepN,
FT                   aminopeptidase N (EC 3.4.11.2), equivalent to Q9CBX9|ML1486
FT                   PROBABLE AMINOPEPTIDASE from Mycobacterium leprae (862 aa),
FT                   FASTA scores: opt: 4751,E(): 0, (83.3% identity in 862 aa
FT                   overlap). Also highly similar to others e.g.
FT                   Q11010|AMPN_STRLI|PEPN from Streptomyces lividans (857 aa),
FT                   FASTA scores: opt: 2839, E(): 1.8e-170, (53.25% identity in
FT                   864 aa overlap); Q9L1Z2|PEPN from Streptomyces coelicolor
FT                   (857 aa), FASTA scores: opt: 2834, E(): 3.8e-170, (53.1%
FT                   identity in 864 aa overlap); P37896|AMPN_LACDL|PEPN from
FT                   Lactobacillus delbrueckii (subsp. lactis) (842 aa), FASTA
FT                   scores: opt: 719, E(): 2.4e-37, (31.65% identity in 439 aa
FT                   overlap); etc. Contains PS00142 Neutral zinc
FT                   metallopeptidases, zinc-binding region signature. BELONGS
FT                   TO PEPTIDASE FAMILY M1 (ZINC METALLOPROTEASE), ALSO KNOWN
FT                   AS THE PEPN SUBFAMILY. Note that previously known as pepD."
FT                   /db_xref="GOA:Q7TYI7"
FT                   /db_xref="InterPro:IPR006025"
FT                   /db_xref="UniProtKB/TrEMBL:Q7TYI7"
FT                   /protein_id="CAD97355.1"
FT                   /translation="MALPNLTRDQAVERAALITVDSYQIILDVTDGNGAPGERTFRSTT
FT                   TVVFDALPGADTVIDISAHTVRRASLNDQDLDVSGYDEAAGIPLRGLAQRNVVVVDADC
FT                   HYSNTGEGLHRFVDPVDGETYLYSQFETADAKRMFACFDQPDLKATFDVRVTAPAHWKV
FT                   ISNGAPLAAANGVHTFATTPRMSTYLVALIAGPYAAWTDTYIDDHGEIPLGIYCRASLA
FT                   EYMDAERLFTQTKQGFGFYHKHFGLPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVF
FT                   RSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWDDLWLNESFATFASVLCQSEATEFT
FT                   EAWTTFATVEKSWAYRQDQLPSTHPIAADIPDLAAVEVNFDGITYAKGASVLKQLVAYV
FT                   GLERFLAGLRDYFRTHAFGNASFDDLLAALEKASGRDLSNWGEQWLKTTGLNTLRPDFE
FT                   VDAEGRFTRFAVTQSGAAPGAGETRVHRLAVGIYDDDGSKSSGKLVRVHREELDVSGPI
FT                   TNVPALVGVSRGKLILVNDDDLTYCSLRLDERSLQTALDRIADIAEPLPRTLVWSAAWE
FT                   MTREAELRARDFVSLVSGGVHAETEVGVAQRLLLQAQTALGCYAEPGWARERGWPQFAD
FT                   RLLELAREAEPGSDHQLAYINSLCSSVLSPRHVQTLGALLEGEPAACGLAGLAVDTDLR
FT                   WRIVTALATAGAIDADGPETPRIDAEVQRDPTAAGKRHAAQARAARPQFVVKDEAFTTV
FT                   VEDDTLANATGRAMIAGIAAPGQGELLKPFARRYFQAIPGVWARRSSEVAQSVVIGLYP
FT                   HWDISEQGITAAEEFLSDPEVPPALRRLVLEGQAAVQRSLRARNFDADG"
FT   CDS             complement(228807..229310)
FT                   /transl_table=11
FT                   /gene="Mb2495c"
FT                   /locus_tag="Mb2495c"
FT                   /product="CONSERVED HYPOTHETICAL PROTEIN"
FT                   /note="Mb2495c, -, len: 167 aa. Equivalent to Rv2468c, len:
FT                   167 aa, from Mycobacterium tuberculosis strain H37Rv,
FT                   (100.0% identity in 167 aa overlap). Conserved hypothetical
FT                   protein, highly similar to Mycobacterium leprae
FT                   HYPOTHETICAL PROTEINS Q9CC58|ML1255 (163 aa), FASTA scores:
FT                   opt: 859, E(): 1.6e-49, (81.2% identity in 165 aa overlap)
FT                   and Q9X7B5|MLCB1610.16 (169 aa), FASTA scores: opt: 859,
FT                   E(): 1.6e-49, (81.2% identity in 165 aa overlap). Also weak
FT                   similarity with Q9X8D7|SCE39.14c PUTATIVE GNTR-FAMILY
FT                   REGULATOR from Streptomyces coelicolor (243 aa), FASTA
FT                   scores: opt: 116, E(): 1.3, (30.1% identity in 156 aa
FT                   overlap)."
FT                   /db_xref="