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EBI DbfetchID BC136645; SV 1; linear; mRNA; STD; HUM; 7402 BP. XX AC BC136645; XX DT 12-FEB-2009 (Rel. 99, Created) DT 12-FEB-2009 (Rel. 99, Last updated, Version 1) XX DE Homo sapiens phosphoinositide-3-kinase, class 2, beta polypeptide, mRNA DE (cDNA clone MGC:168258 IMAGE:9020635), complete cds. XX KW MGC. XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-7402 RX DOI; 10.1073/pnas.242603899 RX PUBMED; 12477932. RG Mammalian Gene Collection Program Team RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human and RT mouse cDNA sequences"; RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002). XX RN [2] RC NIH-MGC Project URL: http://mgc.nci.nih.gov RP 1-7402 RG NIH MGC Project RA ; RT ; RL Submitted (29-MAR-2007) to the EMBL/GenBank/DDBJ databases. RL National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, RL MD 20892-2590, USA XX DR Ensembl-Gn; ENSG00000133056; Homo_sapiens. DR Ensembl-Tr; ENST00000367187; Homo_sapiens. DR Ensembl-Tr; ENST00000424712; Homo_sapiens. DR Ensembl-Tr; ENST00000429009; Homo_sapiens. DR Ensembl-Tr; ENST00000438854; Homo_sapiens. XX CC Contact: MGC help desk CC Email: cgapbs-r@mail.nih.gov CC Tissue Procurement: Ambion CC cDNA Library Preparation: British Columbia Cancer Research Center CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) CC DNA Sequencing by: Genome Sequence Centre, CC BC Cancer Agency, Vancouver, BC, Canada CC info@bcgsc.bc.ca CC Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson CC Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen CC Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel CC Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave CC Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth CC Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao, CC Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR CC Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, CC Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra. CC Clone distribution: MGC clone distribution information can be found CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov CC Series: LLDM Plate: 671 Row: a Column: 17 CC single stranded. XX FH Key Location/Qualifiers FH FT source 1..7402 FT /organism="Homo sapiens" FT /lab_host="DH10B" FT /mol_type="mRNA" FT /clone_lib="NIH_MGC_382" FT /clone="MGC:168258 IMAGE:9020635" FT /tissue_type="Testicle, PCR rescued clones" FT /note="Vector: pCR4-TOPO with reversed insert; Clone FT identification sequence tag: ACGTTTGG" FT /db_xref="taxon:9606" FT gene 1..7402 FT /gene="PIK3C2B" FT /gene_synonym="C2-PI3K" FT CDS 452..5356 FT /codon_start=1 FT /gene="PIK3C2B" FT /gene_synonym="C2-PI3K" FT /product="phosphoinositide-3-kinase, class 2, beta FT polypeptide" FT /db_xref="GOA:A2RUF7" FT /db_xref="HGNC:8972" FT /db_xref="InterPro:IPR000008" FT /db_xref="InterPro:IPR000341" FT /db_xref="InterPro:IPR000403" FT /db_xref="InterPro:IPR001263" FT /db_xref="InterPro:IPR001683" FT /db_xref="InterPro:IPR002420" FT /db_xref="InterPro:IPR008973" FT /db_xref="InterPro:IPR011009" FT /db_xref="InterPro:IPR015433" FT /db_xref="InterPro:IPR016024" FT /db_xref="InterPro:IPR018029" FT /db_xref="InterPro:IPR018936" FT /db_xref="UniProtKB/TrEMBL:A2RUF7" FT /protein_id="AAI36646.1" FT /translation="MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHDKE FT ENRAKQNADPSLISWDEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPN FT HSTSQGPQPGSDPWPKGSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRA FT SIWDTPPLPPRKGSPSSSKISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQGRL FT LGSVDYDGINDAITRLNLKSTYDAEMLRDATRGWKEGRGPLDFSKDTSGKPVARSKTMP FT PQVPPRTYASRYGNRKNATPGKNRRISAAPVGSRPHTVANGHELFEVSEERDEEVAAFC FT HMLDILRSGSDIQDYFLTGYVWSAVTPSPEHLGDEVNLKVTVLCDRLQEALTFTCNCSS FT TVDLLIYQTLCYTHDDLRNVDVGDFVLKPCGLEEFLQNKHALGSHEYIQYCRKFDIDIR FT LQLMEQKVVRSDLARTVNDDQSPSTLNYLVHLQERPVKQTISRQALSLLFDTYHNEVDA FT FLLADGDFPLKADRVVQSVKAICNALAAVETPEITSALNQLPPCPSRMQPKIQKDPSVL FT AVRENREKVVEALTAAILDLVELYCNTFNADFQTAVPGSRKHDLVQEACHFARSLAFTV FT YATHRIPIIWATSYEDFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPV FT QVNRLPRETLLCATLYALPIPPPGSSSEANKQRRVPEALGWVTTPLFNFRQVLTCGRKL FT LGLWPATQENPSARWSAPNFHQPDSVILQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLR FT EEDQRKLKDIMQKESLYWLTDADKKRLWEKRYYCHSEVSSLPLVLASAPSWEWACLPDI FT YVLLKQWTHMNHQDALGLLHATFPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYEC FT YLDSPLVRFLLKRAVSDLRVTHYFFWLLKDGLKDSQFSIRYQYLLAALLCCCGKGLREE FT FNRQCWLVNALAKLAQQVREAAPSARQGILRTGLEEVKQFFALNGSCRLPLSPSLLVKG FT IVPRDCSYFNSNAVPLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQ FT EGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPG FT EDEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQMFG FT NIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLS FT CGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNFFIHNLAQMKF FT TGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFHPNKGYIYVVKVMRENTHEATYI FT QRTFEEFQELHNKLRLLFPSSHLPSFPSRFVIGRSRGEAVAERRREELNGYIWHLIHAP FT PEVAECDLVYTFFHPLPRDEKAMGTSPAPKSSDGTWARPVGKVGGEVKLSISYKNNKLF FT IMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKVARKTCNPTYNEMLVYDGIP FT KGDLQQRELQLSVLSEQGFWENVLLGEVNIRLRELDLAQEKTGWFALGSRSHGTL" XX SQ Sequence 7402 BP; 1613 A; 2050 C; 1989 G; 1750 T; 0 other; gagcagaggc cctcagggta tagagaagga agaagagaga ggttcactgt agtcctgaag 60 cagaaataag acctgtggct gaaggaagcc ttagcaattc actccttcct cttcctgaga 120 actctctgta ggaagtctca cctagcagag gcttcacagt atttcagaga agccaaagat 180 tgtttgcctc tttggaaact gttatccttc catcatgact gtgtcactcc tgccactgtt 240 ccaccataga gatggcgtcc tttgcagcaa accgtaagtt ataaggatga gggaagaaga 300 gtagagggcc aaaaggattc cattttgagg aaaaactaca gtttgccttg ccaggtagaa 360 gaatcaggcg cccagacacc atgtcacaac cctccagaac tgacgttggc aggaagtaga 420 gactttgttg cctgtgtccc ccatcctcac catgtcttcg actcagggca atggggaaca 480 ctggaagtcc ctggagtcag tgggcatcag ccgcaaagag ctagcgatgg ccgaagccct 540 gcagatggag tatgatgccc tgtcccggct ccggcatgac aaggaggaga acagagccaa 600 gcagaacgca gacccctctc tcatcagctg ggatgagcct ggggtagact tttacagcaa 660 gccagcagga aggcggaccg acctcaagct gttacgcggt ctctctggct ctgatcctac 720 ccttaactac aactcactat ccccacagga agggccgccc aaccactcta cctcccaagg 780 gccacagcct ggctcagatc cctggcccaa aggctccctg tctggagact atctctacat 840 ttttgatggt tcagatgggg gagtctcttc gtccccagga ccaggggaca tagagggctc 900 ttgcaagaaa ctatccccac ctcctctgcc tccccgagct tctatctggg atacccctcc 960 cctgcctccc agaaaggggt ccccctcatc ctccaagatc tcccagccca gtgacatcaa 1020 cactttctct ttggtcgaac aattgccagg caaactgcta gagcatcgga tcctagaaga 1080 ggaagaggtg ctgggaggtg ggggtcaggg gcgcctactg gggtctgtgg actatgatgg 1140 tatcaatgat gcaattacta ggctcaactt gaaatcgacc tatgatgcgg agatgttgcg 1200 ggatgccacc aggggctgga aggagggccg agggccgctg gacttcagca aagacacctc 1260 tggaaaaccc gtggccagga gcaagactat gccccctcag gtgccccccc gcacctatgc 1320 ctcccgctat ggcaaccgaa agaatgcgac gcctggcaag aaccgccgga tttctgcagc 1380 cccggtgggc tcccggcccc acactgttgc caatggccat gagttgtttg aggtctcaga 1440 agagagagat gaggaggttg ctgcattttg ccacatgctg gatatccttc gatctggctc 1500 tgacatccaa gactacttcc tcactggcta tgtctggagt gctgtcaccc ctagcccaga 1560 gcacctcggg gatgaggtca acctgaaggt gactgtgttg tgtgacaggc ttcaagaggc 1620 actcactttc acctgcaact gttcctccac tgtagacttg cttatctacc agaccctgtg 1680 ctacacccat gatgacctga ggaatgtgga cgtgggtgac tttgtgctaa agccctgcgg 1740 gctggaggag ttcctgcaga acaagcatgc cttgggcagt catgagtaca tccaatactg 1800 ccgcaagttt gacattgaca ttcggctaca gctgatggag cagaaggttg tgcgcagtga 1860 cctggcccgg acggtgaatg atgaccagag cccctccacc ttgaactacc tcgtccatct 1920 ccaagagagg cctgtcaagc agaccatcag caggcaggcc ctgagtcttc tgttcgacac 1980 ttaccacaat gaggtggatg ccttcctgct ggctgatgga gacttcccac tgaaggctga 2040 cagggtggtc cagtccgtca aggccatctg caacgccctg gccgccgtgg aaacccctga 2100 gatcaccagt gctctcaacc agctgccccc ctgcccctcc cgcatgcagc ctaaaattca 2160 gaaggatccc agtgtcttgg ctgtgaggga aaaccgagag aaggtcgtgg aagccctgac 2220 cgctgccatc ttggacctgg tggagctgta ctgcaacaca ttcaacgcag acttccagac 2280 ggcagtgccc gggagccgca agcatgacct ggtccaggag gcctgccatt tcgccaggtc 2340 cctggccttc actgtctatg ccacccaccg catccccatc atctgggcta ccagctatga 2400 agatttctac ctctcctgct ccctcagcca tggcggcaag gagctgtgca gccccctgca 2460 gacccgaaga gctcacttct ccaagtacct cttccacctc atcgtctggg accagcagat 2520 ctgcttccca gtgcaggtga accggctgcc tcgggagaca ctgctgtgtg ccactctcta 2580 tgctctgccc atccccccac cggggagctc ctcagaggcc aataagcagc ggcgggtgcc 2640 tgaagccctg ggctgggtca ctaccccact cttcaacttc aggcaggtcc tgacctgtgg 2700 ccggaagctt ctgggtttgt ggccagcaac acaggaaaat cccagcgccc gttggagtgc 2760 acctaatttc caccagccag acagtgtcat cctgcagatt gacttcccca cctcggcctt 2820 tgacatcaag ttcaccagcc cccctggaga caagttcagc ccccgctatg agtttggcag 2880 cctccgggaa gaagaccagc gcaagcttaa agacatcatg cagaaagagt ccttgtactg 2940 gctcactgat gctgacaaga agcgcctgtg ggagaagcga tattactgcc actcggaggt 3000 gagctcgctc cccctggtgc tcgccagcgc ccccagctgg gagtgggctt gcctgcctga 3060 catctatgtt ctcctgaagc agtggaccca catgaaccac caggatgccc tggggctcct 3120 gcatgccacc ttcccggacc aggaggtgcg tcgtatggct gtgcagtgga ttggctcact 3180 ctcagatgct gagctgctag actacctgcc ccagctggta caggccctga agtatgaatg 3240 ctacctggac agcccgttgg tgcgcttcct cctgaaacga gctgtgtctg acttgagagt 3300 gactcactac ttcttctggt tactgaagga cggcctcaag gactctcagt tcagcatccg 3360 ctaccagtat ctgctggcag ccttactgtg ctgctgtggc aaggggctga gagaagagtt 3420 taaccgccag tgctggcttg tcaatgccct ggccaaactg gcccagcagg tccgggaggc 3480 agccccatct gcaaggcagg gaatcctccg cacgggcctg gaggaggtga agcagttctt 3540 tgccctcaat ggctcgtgcc gcttgccact cagccccagt ctgctggtta agggaattgt 3600 gcccagggac tgttcctact tcaactccaa tgctgtcccc ctcaaactct ccttccaaaa 3660 tgtggatccc ctgggtgaga acatccgtgt catcttcaag tgtggggacg accttcgcca 3720 ggacatgcta acgctgcaga tgattcgcat catgagcaag atctgggtcc aggaggggct 3780 ggacatgcgc atggtcatct tccgctgctt ctccaccggc cggggcagag ggatggtgga 3840 gatgatccct aatgctgaga ccctgcgtaa gatccaggtg gagcatgggg tgaccggctc 3900 gttcaaggac cggcccctgg cagactggct gcagaaacac aaccctgggg aggacgagta 3960 tgagaaggct gtggagaact ttatctactc ctgcgctggc tgctgcgtgg ccacgtacgt 4020 cttgggcatc tgtgaccgac ataatgacaa catcatgctg aagaccactg gtcacatgtt 4080 ccacattgat tttggccgct tcctgggcca tgcccagatg tttggcaaca tcaagcggga 4140 ccgtgccccc tttgtcttca cctcggacat ggcgtatgtc atcaacgggg gtgacaagcc 4200 ttccagccgc ttccatgatt ttgttgacct ttgctgccaa gcctacaacc tcattcgcaa 4260 gcacacccac ctcttcctca accttctggg cctgatgttg tcctgtggga tccctgaact 4320 ctcagacctg gaggacctca agtatgtgta cgatgccctg aggcctcagg atacagaggc 4380 caatgccact acctacttca ctaggttgat tgagtccagc ctgggcagtg tagccacaaa 4440 gctcaatttt ttcatccata atctggctca gatgaagttc acgggctcag atgaccggct 4500 gaccctctcc tttgcctccc gaacacacac tctcaagagc tctggccgaa tcagtgatgt 4560 tttcctctgc cgccatgaga agatcttcca ccccaacaaa ggctatatat atgtggtaaa 4620 ggtgatgcga gagaacactc acgaggccac ctacatccag cggacctttg aggagttcca 4680 ggaattacac aataagttgc ggctgctctt cccttcttcc cacttgccca gcttccctag 4740 tcgcttcgtg atcggccgct cccggggaga ggcggtggcc gagcggcgga gggaggagct 4800 aaacggttac atctggcact tgatccacgc accccctgag gtggccgagt gtgatttggt 4860 gtacaccttc ttccacccac tgccccggga tgagaaggct atgggcacca gcccagctcc 4920 taagtcctca gatggcacat gggcccggcc cgtcggaaag gtgggagggg aggtgaagct 4980 gtccatctcc tacaaaaaca ataaactctt catcatggtg atgcatattc ggggcttgca 5040 actgctccag gatggaaatg accctgaccc ctatgtgaaa atttacctcc ttcctgaccc 5100 tcagaaaacc actaagagga aaaccaaagt ggcccggaaa acctgcaatc ctacctacaa 5160 tgagatgttg gtatatgatg ggatccccaa gggtgacctg cagcagcggg agctccagct 5220 gagcgtgctg agtgagcagg gattctggga gaacgtcctc ctcggtgagg tgaacatccg 5280 cctgcgagag ctggacctgg ctcaggagaa gaccggctgg ttcgccctgg gatctcgaag 5340 tcatggcacc ttgtgagccc agcagagcca ccacccagca tcccaggctg gtggcaggag 5400 ctgggggaga ggactctccc ctgtgagact cctccttgtg aagggccagg gccctgggca 5460 ggcctccagc tcggtccagg tgattctggc ctctgtggta ggaggcaggg agagtaagac 5520 atgctctgct gtctcttcct ctggagactg aacttgggtt ggttgtgatg agcagcccct 5580 tggaggctgt gaggttgcag caaagtttta agtttacctt gtgtcaaggg agcaatgctt 5640 ggtttgggga gtgtgtgggg tgggctgtat gaagtagcat tttgggggtg ggtgggtgga 5700 tatcttaatt tttattttta aaaaatgaaa tagtgatgtt gtcctaactg ggacaggaag 5760 ccttgcgaga agggacgtac ctatgcccca gaaggcaaga gaggaagact atttggactt 5820 tttgtatgat taaggttctt attggacttt tccctaggtt tttttttttt gttattgttg 5880 ttgttgtttc gttttctagc tataggaact atctggggag gggcccagtg ggtcctcggc 5940 cagagccctc tctaaggaca ggttggggag ggttggggag ggctgcctgt gctggactga 6000 ggcttgtgcc actgggcctt tctgattttg cctccaaagg agagcgctgt gatacctaca 6060 tgtgtaagga agggccttcc gtattggggt tctgccaagg acccgtattc agggacccat 6120 gctcttttgg ggggactttt cctcttgtct tccctacttt attaggactt gccctgaata 6180 ccattttcta ccccttgccc ctccattctc ctggcccttc tgggggtcag ctggtctcta 6240 tgaatatgct gggggtgctt ccccataggt ctctcccttc atttgtctct ggtgggacaa 6300 aatactgact cagtccttag atgtagtttc acccaagagc atcttggccc tgggaagagg 6360 tccctaggct gcagatgcta ctgactgctt gctaggtagc ctctggaaag cattccccat 6420 ccatcactcc ccacttcttt ctgctgtgct gcttccctcc caaactccat ttctgtcacc 6480 ctttttataa gacttttcct cattctgtgg ggccataaac ctatttagtc tggagccaaa 6540 gggatgccct atctgaagga aaggggcatg gggtggggga ttccatcaaa actgttgttt 6600 tttgccccat gatttttctt tggtcagtag gaggctggat tggagtggtg attattcccc 6660 tggagctaag ctcaggagcc cgaagggaga gactgagact gactccctta tctcttcata 6720 ttctttattc cctaccagat ggattttttt tttttttttt ggagacggag tctcgccctg 6780 tcgccaggct ggagtgtagt ggcatgatct cgactcactg caaaatctgc ctcccgggtt 6840 caagcgattc tcctacctca gcctcccgag tagctgggat tacaggcatg tgccaccacg 6900 ccaagctaat ttttgtattt ttagtagaga cggggtttca ccatgttggc caggatggtc 6960 tcgatctctt gacctcgtga tctgcctgcc ttggcctccc aaagtgctgg gattacaggc 7020 gtgagccacc atgccccgcc ccagatggat tttacatttg ctcttttgtg tttcgctcca 7080 aagggttgtc ttcctcgcca aaaggaggga gggactttga atttgatatg aatctttaaa 7140 accagaattg gctggatatt tcccatgatt gggaaaagag tgaaatgagg acattctgta 7200 aactgtccct ccctaattcc aaggatcaga aactccccgt tttgctgact cattccataa 7260 ctggagaaag aagctccatt gaccgaagcc acagggcagc atggaagttt aaattttctc 7320 taaaattaaa atgccaagga taaagctggc tgcttccagg agggggaaga ggagtgggga 7380 gtgggcggtg aaacttttcc ag 7402 // |
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