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EBI DbfetchID BC053078; SV 1; linear; mRNA; STD; MUS; 4695 BP. XX AC BC053078; XX DT 06-JUN-2003 (Rel. 76, Created) DT 24-SEP-2008 (Rel. 97, Last updated, Version 9) XX DE Mus musculus v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, DE neuro/glioblastoma derived oncogene homolog (avian), mRNA (cDNA clone DE MGC:62447 IMAGE:5702040), complete cds. XX KW MGC. XX OS Mus musculus (house mouse) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; OC Muridae; Murinae; Mus. XX RN [1] RP 1-4695 RX DOI; 10.1073/pnas.242603899 RX PUBMED; 12477932. RG Mammalian Gene Collection Program Team RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human and RT mouse cDNA sequences"; RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002). XX RN [2] RC NIH-MGC Project URL: http://mgc.nci.nih.gov RP 1-4695 RG NIH MGC Project RA ; RT ; RL Submitted (02-JUN-2003) to the EMBL/GenBank/DDBJ databases. RL National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, RL MD 20892-2590, USA XX DR ASTD; TRAN00000150877. DR Ensembl-Gn; ENSMUSG00000062312; Mus_musculus. DR Ensembl-Tr; ENSMUST00000058295; Mus_musculus. DR ImaGenes; IMAGp998G0112655Q. DR ImaGenes; IRAKp961F22114Q. DR ImaGenes; IRAVp968C03158D. XX CC Contact: MGC help desk CC Email: cgapbs-r@mail.nih.gov CC Tissue Procurement: Dr. Jim Lin, University of Iowa CC cDNA Library Preparation: M. Bento Soares, University of Iowa CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) CC DNA Sequencing by: Sequencing Group at the Stanford Human Genome CC Center, Stanford University School of Medicine, Stanford, CA 94305 CC Web site: http://www-shgc.stanford.edu CC Contact: (Dickson, Mark) mcd@paxil.stanford.edu CC Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers, CC R. M. CC Clone distribution: MGC clone distribution information can be found CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov CC Series: IRAK Plate: 114 Row: f Column: 22 CC This clone was selected for full length sequencing because it CC passed the following selection criteria: Hexamer frequency ORF CC analysis, Similarity but not identity to protein. XX FH Key Location/Qualifiers FH FT source 1..4695 FT /organism="Mus musculus" FT /lab_host="DH10B" FT /strain="C57BL/6" FT /mol_type="mRNA" FT /clone_lib="NIH_BMAP_FI0" FT /clone="MGC:62447 IMAGE:5702040" FT /tissue_type="Brain, enriched mouse brain 12.5dpc" FT /note="Vector: pYX-ASC" FT /db_xref="taxon:10090" FT gene 1..4695 FT /gene="Erbb2" FT /note="synonyms: Neu, HER-2, c-erbB2, HER2, c-neu, FT mKIAA3023" FT CDS 171..2306 FT /codon_start=1 FT /gene="Erbb2" FT /product="Erbb2 protein" FT /db_xref="GOA:Q80Y89" FT /db_xref="HSSP:1N8Y" FT /db_xref="InterPro:IPR000494" FT /db_xref="InterPro:IPR006211" FT /db_xref="InterPro:IPR006212" FT /db_xref="InterPro:IPR009030" FT /db_xref="InterPro:IPR020685" FT /db_xref="MGI:95410" FT /db_xref="UniProtKB/TrEMBL:Q80Y89" FT /protein_id="AAH53078.1" FT /translation="MELAAWCRWGFLLALLSPGAAGTQVCTGTDMKLRLPASPETHLDM FT LRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRG FT TQLFEDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLC FT YQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICT FT SGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFE FT SMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCA FT GVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQ FT VFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRS FT LRELGSGLALIHRNTHLCFVNTVPWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCA FT RGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVRGKHCLPCHPECQPQNSSET FT CYGSEADQCEACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSC FT VDLDERGCPAEQRASPVTFIIATVVGVLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQE FT TEVRRAEGLLAPPWLCS" FT misc_difference 4610..4695 FT /gene="Erbb2" FT /note="polyA tail: 86 bases do not align to the mouse FT genome; Differences found between this sequence and the FT mouse C57BL/6J genome (build 33) are described in FT misc_difference features below" XX SQ Sequence 4695 BP; 1057 A; 1346 C; 1317 G; 975 T; 0 other; gcggcgtgaa gttgtggagc tgagattgcc cgccgctggg gacccggagc ccaggagcgc 60 cccttcccag gcggcccctt ccggcgccgc gcctgtgcct gccctcgccg cgccccgcgc 120 ccgcagcctg gtccagcctg agccatgggg ccggagccgc agtgatcatc atggagctgg 180 cggcctggtg ccgttggggg ttcctcctcg ccctcctgtc ccccggagcc gcgggtaccc 240 aagtgtgtac cggtaccgac atgaagttgc gactccctgc cagtcctgag acccacctgg 300 acatgcttcg ccacctctac cagggctgtc aggtggtgca gggcaatttg gagcttacct 360 acctgcccgc caatgccagc ctctcattcc tgcaggacat ccaggaagtc cagggataca 420 tgctcatcgc tcacaaccga gtgaaacacg tcccactgca gaggttgcgc atcgtgagag 480 ggactcagct ctttgaggac aagtatgccc tggctgtgct agacaaccga gaccctttgg 540 acaacgtcac caccgccgcc ccaggcagaa ccccagaagg gctgcgggag ctgcagcttc 600 gaagtctcac agagatcttg aagggaggag ttttgatccg tgggaaccct cagctctgct 660 accaggacat ggttttgtgg aaggatgtcc tccgtaagaa taaccagctg gctcctgtcg 720 acatggacac caatcgttcc cgggcctgtc caccttgtgc cccaacctgc aaagacaatc 780 actgttgggg tgagagtcct gaagactgtc agatcttgac tggcaccatc tgtactagtg 840 gctgtgcccg gtgcaagggc cggctgccca ctgactgttg ccatgagcag tgtgctgcag 900 gctgcacggg tcccaagcat tctgactgcc tggcctgcct ccacttcaat catagtggta 960 tctgtgagct gcactgcccg gccctcatca cctacaacac agacaccttc gagtccatgc 1020 tcaaccctga gggtcgctac acctttggtg ccagctgtgt gaccacctgc ccctacaact 1080 acctctccac ggaagtggga tcctgcactc tggtctgtcc cccgaacaac caagaggtca 1140 cagctgagga cggaacacag cggtgtgaga aatgcagcaa gccctgtgct ggagtatgct 1200 atggtctggg catggagcac ctccgagggg cgagggccat caccagtgac aatatccagg 1260 agtttgctgg ctgcaagaag atctttggga gcctggcatt tttgccggag agctttgatg 1320 ggaacccctc ctccggcgtt gccccactga agccagagca tctccaagtg ttcgaaaccc 1380 tggaggagat cacaggttac ctatacattt cagcatggcc agagagcttc caagacctca 1440 gtgtcttcca gaaccttcgg gtcattcggg gacggattct ccatgatggt gcttactcat 1500 tgacgttgca aggcctgggg attcactcac tggggctacg ctcactgcgg gagctgggca 1560 gtggattggc tctcattcac cgcaacaccc atctctgctt tgtaaacact gtaccttggg 1620 accagctctt ccggaacccg caccaggccc tactccacag tgggaaccgg ccagaagagg 1680 catgtggtct tgagggcttg gtctgtaact cactgtgtgc ccgtgggcac tgctgggggc 1740 cagggcccac ccagtgtgtc aactgcagtc agttcctccg gggccaggag tgtgtggagg 1800 agtgccgagt atggaagggg ctccccaggg agtatgtgag gggcaagcac tgtctgccat 1860 gccaccccga gtgtcagcct caaaacagct cggagacctg ctatggatcg gaggctgacc 1920 agtgtgaggc ttgtgcccac tacaaggact catcttcctg tgtggctcgc tgccccagtg 1980 gtgtgaagcc agacctctcc tacatgccta tctggaagta cccggatgag gagggcatat 2040 gtcagccatg ccccatcaac tgcacccact catgtgtgga cctggacgaa cgaggctgcc 2100 cagcagagca gagagccagc ccagtgacat tcatcattgc aactgtggtg ggcgtcctgt 2160 tgttcctgat catagtggtg gtcattggaa tcctaatcaa acgaaggcga cagaagatcc 2220 ggaagtatac catgcgtagg ctgctgcagg agaccgaggt gaggcgtgcc gagggcctcc 2280 tagcaccccc ttggctttgc agctagctgg gcattcaccc taccaccctc tcgctccagc 2340 tggtggagcc gctgacgccc agtggagctg tgcccaacca ggctcagatg cggatcctaa 2400 aggagacaga gctaaggaag ctgaaggtgc ttgggtcagg agccttcggc actgtctaca 2460 agggcatctg gatcccagat ggggagaacg tgaaaatccc cgtggccatc aaggtgttga 2520 gggaaaacac atctcctaaa gctaacaaag aaatcctaga tgaagcgtac gtcatggctg 2580 gtgtgggttc tccatatgtg tcccgcctcc tgggcatctg cctgacatcc acagtgcagc 2640 tggtgacaca gcttatgccc tatggctgcc ttctggacca tgtccgagaa caccgaggtc 2700 gcttaggctc ccaggacctg ctcaactggt gtgttcagat tgccaagggg atgagctacc 2760 tggaggaagt tcggcttgtt cacagggacc tagctgcccg aaacgtgcta gtcaagagtc 2820 ccaaccacgt caagattacc gacttcgggc tggcacggct gctggacatt gatgagactg 2880 aataccatgc agatgggggc aaggtgccca tcaagtggat ggcattggaa tctattctca 2940 gacgccggtt cacccatcag agtgatgtgt ggagctatgg tgtgactgtg tgggagctga 3000 tgacctttgg ggccaaacct tacgatggga tcccagctcg ggagatccct gatttgctgg 3060 agaagggaga acgcctacct cagcctccaa tctgcaccat cgacgtctac atgatcatgg 3120 tcaaatgttg gatgattgac tccgaatgtc gcccgagatt ccgggagttg gtatcagaat 3180 tctcccgtat ggcaagggac ccccagcgct ttgtggtcat ccagaacgag gacttaggcc 3240 cctccagccc catggacagc accttctacc gttcactgct ggaggatgat gacatggggg 3300 agctggtcga tgctgaagag tacctggtac cccagcaggg attcttctcc ccagaccctg 3360 ccctaggtac tgggagcaca gcccaccgca gacaccgcag ctcgtcggcc aggagtggcg 3420 gtggtgagct gacactgggc ctggagccct cggaagaaga gccccccaga tctccactgg 3480 ctccctccga aggggctggc tccgatgtgt ttgatggtga cctggcagtg ggggtaacca 3540 aaggactgca gagcctctct ccacatgacc tcagccctct acagcggtac agtgaggatc 3600 ccacattacc tctgcccccc gagactgatg gctacgttgc tcccctggcc tgcagccccc 3660 agcccgagta tgtgaaccag ccagaggttc ggcctcagtc tcccttgacc ccagagggtc 3720 ctccgcctcc catccgacct gctggtgcta ctctagaaag acccaagact ctctctcctg 3780 ggaaaaatgg ggttgtcaaa gacgtttttg cctttggggg tgctgtggag aaccctgaat 3840 acttagcacc cagagcaggc actgcctctc agccccaccc ttctcctgcc ttcagcccag 3900 cctttgacaa cctctattac tgggaccaga actcatcgga gcagggtcct ccaccaagta 3960 cctttgaagg gacccccact gcagagaacc ctgagtacct aggcctggat gtgccagtat 4020 gaggtcacat gtgcagacat cctctgtctt cagagtgggg aaggaaggcc taacttgtgg 4080 tctccatcgc ccgccacaaa gcagggagaa ggtcctctgg ccacatgaca tccagggcag 4140 ccggctatgc caggaacgtg ccctgaggaa cctcgctcga tgcttcaatc ctgagtggtt 4200 aagagggccc cgcctggccg gaagagacag cacactgttc agccccagag gattacagac 4260 cctgactgcc ctgacagact gtagggtcca gtgggtattc cttacctggc ctggctctct 4320 tggttctgaa gactgaggga agctcagcct gcaagggagg aggccccagg tgaatatcct 4380 gggagcagga caccccacta ggactgaggc acgtgcatcc caagaggggg acagcacttg 4440 cacccagact ggtctttgta cagagtttat tttgttctgt ttttactttt gttttttgtt 4500 ttttttttaa agatgaaata aggatacagt gggagagtgg gtgttatatg aaagtcgggg 4560 ggtgctgtcc cctttctcca tttgcaatga gatttgtaaa ataactggaa aaaaaaaaaa 4620 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4680 aaaaaaaaaa aaaaa 4695 // |
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