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EBI DbfetchID BC024779; SV 1; linear; mRNA; STD; HUM; 2536 BP. XX AC BC024779; XX DT 14-MAR-2002 (Rel. 71, Created) DT 15-OCT-2008 (Rel. 97, Last updated, Version 11) XX DE Homo sapiens abhydrolase domain containing 4, mRNA (cDNA clone MGC:29836 DE IMAGE:5122692), complete cds. XX KW MGC. XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-2536 RX DOI; 10.1073/pnas.242603899 RX PUBMED; 12477932. RG Mammalian Gene Collection Program Team RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human and RT mouse cDNA sequences"; RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002). XX RN [2] RC NIH-MGC Project URL: http://mgc.nci.nih.gov RP 1-2536 RG NIH MGC Project RA ; RT ; RL Submitted (01-MAR-2002) to the EMBL/GenBank/DDBJ databases. RL National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, RL MD 20892-2590, USA XX DR Ensembl-Gn; ENSG00000100439; Homo_sapiens. DR Ensembl-Tr; ENST00000216327; Homo_sapiens. DR Ensembl-Tr; ENST00000418446; Homo_sapiens. DR Ensembl-Tr; ENST00000428304; Homo_sapiens. DR H-InvDB; HIT000039841. DR ImaGenes; IMAGp998K1311299Q. DR ImaGenes; IRAKp961N1642Q. DR ImaGenes; IRATp970B0542D. XX CC Contact: MGC help desk CC Email: cgapbs-r@mail.nih.gov CC Tissue Procurement: ATCC CC cDNA Library Preparation: Life Technologies, Inc. CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) CC DNA Sequencing by: Baylor College of Medicine Human Genome CC Sequencing Center CC Center code: BCM-HGSC CC Web site: http://www.hgsc.bcm.tmc.edu/cdna/ CC Contact: amg@bcm.tmc.edu CC Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H., CC Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati, CC A.N., Gibbs, R.A. CC Clone distribution: MGC clone distribution information can be found CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov CC Series: IRAK Plate: 42 Row: n Column: 16 CC This clone was selected for full length sequencing because it CC passed the following selection criteria: matched mRNA gi: 50658086. CC Differences found between this sequence and the human reference CC genome (build 36) are described in misc_difference features below CC and these differences were also compared to chimpanzee genomic CC sequences available as of 09/15/2004. XX FH Key Location/Qualifiers FH FT source 1..2536 FT /organism="Homo sapiens" FT /lab_host="DH10B" FT /mol_type="mRNA" FT /clone_lib="NIH_MGC_12" FT /clone="MGC:29836 IMAGE:5122692" FT /tissue_type="Cervix, carcinoma" FT /note="Vector: pCMV-SPORT6" FT /db_xref="taxon:9606" FT gene 1..2536 FT /gene="ABHD4" FT /note="synonym: FLJ12816" FT CDS 18..1046 FT /codon_start=1 FT /gene="ABHD4" FT /product="abhydrolase domain containing 4" FT /db_xref="GDB:11519176" FT /db_xref="GOA:Q8TB40" FT /db_xref="HGNC:20154" FT /db_xref="InterPro:IPR000073" FT /db_xref="UniProtKB/Swiss-Prot:Q8TB40" FT /protein_id="AAH24779.1" FT /translation="MADDLEQQSQGWLSSWLPTWRPTSMSQLKNVEARILQCLQNKFLA FT RYVSLPNQNKIWTVTVSPEQNDRTPLVMVHGFGGGVGLWILNMDSLSARRTLHTFDLLG FT FGRSSRPAFPRDPEGAEDEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRV FT KHLILVDPWGFPLRPTNPSEIRAPPAWVKAVASVLGRSNPLAVLRVAGPWGPGLVQRFR FT PDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDV FT PITMIYGSDTWIDTSTGKKVKMQRPDSYVRDMEIKGASHHVYADQPHIFNAVVEEICDS FT VD" FT misc_difference 1871 FT /gene="ABHD4" FT /note="'G' in cDNA is 'A' in the human genome. The FT chimpanzee genome agrees with the cDNA sequence, suggesting FT that this difference is unlikely to be due to an artifact." FT misc_difference 2216 FT /gene="ABHD4" FT /note="'T' in cDNA is 'C' in the human genome. The FT chimpanzee genome agrees with the human genomic sequence FT and not the cDNA." FT misc_difference 2415 FT /gene="ABHD4" FT /note="'C' in cDNA is 'T' in the human genome." FT misc_difference 2458..2536 FT /gene="ABHD4" FT /note="polyA tail: 79 bases do not align to the human FT genome." XX SQ Sequence 2536 BP; 611 A; 721 C; 627 G; 577 T; 0 other; ggcaaggctt gtttactatg gccgatgatc tggagcagca gtctcaaggc tggctgagta 60 gctggctgcc cacgtggcgc cccacttcca tgtctcagct gaagaatgtg gaagccagga 120 tcctccagtg tctccagaat aagttcctgg ccagatatgt atccctccca aaccagaata 180 agatctggac ggtgactgtg agccccgagc aaaacgaccg cacccccttg gtgatggtgc 240 atggttttgg gggcggcgtg ggtctctgga tcctcaacat ggactcactg agtgcccgcc 300 gcacactgca caccttcgat ctgcttggct tcgggcgaag ctcaaggcca gcattcccaa 360 gggacccgga gggggctgag gatgagtttg tgacatcgat agagacatgg cgggagacca 420 tggggatccc cagcatgatc ctcctggggc acagtttggg aggattcctg gccacttctt 480 actcaatcaa gtaccctgat agagttaaac acctcatcct ggtggaccca tggggctttc 540 ccctccgacc aactaacccc agtgagatcc gtgcaccccc agcctgggtc aaagccgtgg 600 catctgtcct aggacgttcc aatccattgg ctgttcttcg agtagctggg ccctgggggc 660 ctggtctggt gcagcgattc cggccggact tcaaacgcaa gtttgcagac ttctttgaag 720 atgataccat atcagagtat atttaccact gcaacgcaca gaatcccagt ggtgagacag 780 cattcaaagc catgatggag tcctttggct gggcccggcg ccctatgctg gagcgaattc 840 acttgattcg aaaagatgtg cctatcacta tgatctacgg gtccgacacc tggatagata 900 ccagtacggg aaaaaaggtg aagatgcagc ggccggattc ctatgtccga gacatggaga 960 ttaagggtgc ctcccaccat gtctatgctg accagccaca catcttcaat gctgtggtgg 1020 aggagatctg cgactcagtt gattgagctg ctctctgaag aggaagagga gaaagccaga 1080 gagtcactct tacctccctg tctgcttact cacccactct gtcctttcct caccaactaa 1140 catgtgccag ccaggcagag tcttgtgctg ttcccagaac aggacgacag tgaaaagaac 1200 actcttgacc ctacactgaa ggctgaaggc agaagccaca agaggccttg agtgccaccc 1260 ccagggaaga acataaaggg ttgcacaatg ccacccatcc actccttgcc aagtgttacc 1320 cagatggtgg aggatgtgaa gggattgcac caagccacat tcactctctc tgtggccttt 1380 cttcctctgg gcaaagaagg gcttccagtg gcctttcctc actctgtagt gtttgtgggg 1440 ataggttcca tgcaagaaca ccttcctcct ccatccccca cttcacccca tcccatacca 1500 gttccatcca gggtctgctt aactgccaag agcaggtcct ggagttccct tcacctgcag 1560 agtccttttc atgacctagg aggtcttatt caaagccctc attgacagag gaggaaacag 1620 gccaaggcag gacatggctg gaccatggtg atacagctct gtgtgattca agttctggca 1680 gagcttgtaa ggctagagcc caggtctgcc gacaccctgt gcttgttgca cacttgattt 1740 gctaaggctg gagacaggca ccattgccat ggggctggtc ctagtcactg gccgaggata 1800 agcccgtccc tgtcccacat tctagcccca ctatgcgggg gtgctgttgt cctgcctgtg 1860 tctcatcccc ggctgcctaa gctagggaca ctcaagtgct tccttccttg ccccatcttc 1920 ctcccaactg gaggcctctg agcctcccct gtgccttggg ccctgaagcc ccatatgtag 1980 tatagagcaa aggtggctcc tggtgaagag agggtggaaa ggcccttcag ccccagggcc 2040 atgtctgggt tctccatgcc catcagtctc tgcagtttct ctacctgccc ccagagctga 2100 ggccatctgc aagcccctgc ccatggccca atggggagcc tccagccaca agttccctgt 2160 ccttatcagc cactgggtgg ttcccactgc atgaccctct atccctgcca tctgttccca 2220 tggtttccag ctcaatccac ccctgaccca tctgtcagct ttttcccagg gagccgtttc 2280 aggggttctg ggcagtaggc tgggcctggc ctcagaacct ggtggctcct gcctgctcct 2340 tcacttttgt aaaaccatcc ccttcaccag aatggtatta actcctggtg ctttgtacta 2400 ctggtccagc tgccctgggc tccttttcta tattaataaa gaaacgagta aaaattaaaa 2460 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2520 aaaaaaaaaa aaaaaa 2536 // |
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