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EBI DbfetchID BC003182; SV 1; linear; mRNA; STD; HUM; 3394 BP. XX AC BC003182; XX DT 09-MAR-2001 (Rel. 67, Created) DT 15-OCT-2008 (Rel. 97, Last updated, Version 8) XX DE Homo sapiens glycogen synthase 1 (muscle), mRNA (cDNA clone MGC:4430 DE IMAGE:2958297), complete cds. XX KW MGC. XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-3394 RX DOI; 10.1073/pnas.242603899 RX PUBMED; 12477932. RG Mammalian Gene Collection Program Team RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., RA Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., RA Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., RA Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., RA Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., RA Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., RA Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., RA Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., RA Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., RA Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., RA Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., RA Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human and RT mouse cDNA sequences"; RL Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002). XX RN [2] RC NIH-MGC Project URL: http://mgc.nci.nih.gov RP 1-3394 RA Strausberg R.; RT ; RL Submitted (13-FEB-2001) to the EMBL/GenBank/DDBJ databases. RL National Institutes of Health, Mammalian Gene Collection (MGC), Cancer RL Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03, RL Bethesda, MD 20892-2590, USA XX DR Ensembl-Gn; ENSG00000104812; Homo_sapiens. DR Ensembl-Tr; ENST00000263276; Homo_sapiens. DR H-InvDB; HIT000031496. DR ImaGenes; IMAGp958D1048Q. DR ImaGenes; IOH5146. DR ImaGenes; IRALp962D229Q. DR ImaGenes; IRAUp969D1119D. XX CC Contact: MGC help desk CC Email: cgapbs-r@mail.nih.gov CC Tissue Procurement: DCTD/DTP CC cDNA Library Preparation: Rubin Laboratory CC cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) CC DNA Sequencing by: Genome Sequence Centre, CC BC Cancer Agency, Vancouver, BC, Canada CC info@bcgsc.bc.ca CC Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield, CC Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin, CC Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo CC Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven CC Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline CC Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott, CC Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy, CC George Yang, Scott Zuyderduyn, Marco Marra. CC Clone distribution: MGC clone distribution information can be found CC through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov CC Series: IRAL Plate: 9 Row: d Column: 22 CC This clone was selected for full length sequencing because it CC passed the following selection criteria: matched mRNA gi: 4504232. XX FH Key Location/Qualifiers FH FT source 1..3394 FT /organism="Homo sapiens" FT /lab_host="DH10B-R" FT /mol_type="mRNA" FT /clone_lib="NIH_MGC_14" FT /clone="MGC:4430 IMAGE:2958297" FT /tissue_type="Kidney, renal cell adenocarcinoma" FT /note="Vector: pOTB7" FT /db_xref="taxon:9606" FT gene 1..3394 FT /gene="GYS1" FT /note="synonym: GYS" FT CDS 199..2220 FT /codon_start=1 FT /product="GYS1 protein" FT /db_xref="GOA:Q9BTT9" FT /db_xref="HGNC:4706" FT /db_xref="InterPro:IPR008631" FT /db_xref="UniProtKB/TrEMBL:Q9BTT9" FT /protein_id="AAH03182.1" FT /translation="MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYT FT VLQTKAKVTGDEWGDNYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKFLAQ FT SEEKPHVVAHFHEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENF FT NVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKK FT FSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEA FT LARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKL FT YESLLVGSLPDMNKMLDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRI FT GLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVM FT GIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQ FT RIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPA FT SVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASC FT TSSTSGSKRNSVDTATSSSLSTPSEPLSPTSSLGEERN" FT misc_feature 1480..1608 FT /note="Glycos_transf_1; Region: Glycosyl transferases group FT 1. Mutations in this domain may lead to disease (Paroxysmal FT Nocturnal haemoglobinuria). Members of this family transfer FT activated sugars to a variety of substrates, including FT glycogen, Fructose-6-phosphate and lipopolysaccharides. FT Members of this family transfer UDP, ADP, GDP or CMP linked FT sugars. The eukaryotic glycogen synthases may be distant FT members of this family" XX SQ Sequence 3394 BP; 718 A; 1060 C; 913 G; 703 T; 0 other; cagtgacgct gcggcctcct tctgcctagg tcccaacgct tcggggcagg ggtgcggtct 60 tgcaatagga agccgagcgt cttgcaagct tcccgtcggg caccagctac tcggccccgc 120 accctacctg gtgcattccc tagacacctc cggggtccct acctggagat ccccggagcc 180 ccccttcctg cgccagccat gcctttaaac cgcactttgt ccatgtcctc actgccagga 240 ctggaggact gggaggatga attcgacctg gagaacgcag tgctcttcga agtggcctgg 300 gaggtggcta acaaggtggg tggcatctac acggtgctgc agacgaaggc gaaggtgaca 360 ggggacgaat ggggcgacaa ctacttcctg gtggggccgt acacggagca gggcgtgagg 420 acccaggtgg aactgctgga ggcccccacc ccggccctga agaggacact ggattccatg 480 aacagcaagg gctgcaagtt cctggcacag agtgaggaga agccacatgt ggttgctcac 540 ttccatgagt ggttggcagg cgttggactc tgcctgtgtc gtgcccggcg actgcctgta 600 gcaaccatct tcaccaccca tgccacgctg ctggggcgct acctgtgtgc cggtgccgtg 660 gacttctaca acaacctgga gaacttcaac gtggacaagg aagcagggga gaggcagatc 720 taccaccgat actgcatgga aagggcggca gcccactgcg ctcacgtctt cactactgtg 780 tcccagatca ccgccatcga ggcacagcac ttgctcaaga ggaaaccaga tattgtgacc 840 cccaatgggc tgaatgtgaa gaagttttct gccatgcatg agttccagaa cctccatgct 900 cagagcaagg ctcgaatcca ggagtttgtg cggggccatt tttatgggca tctggacttc 960 aacttggaca agaccttata cttctttatc gccggccgct atgagttctc caacaagggt 1020 gctgacgtct tcctggaggc attggctcgg ctcaactatc tgctcagagt gaacggcagc 1080 gagcagacag tggttgcctt cttcatcatg ccagcgcgga ccaacaattt caacgtggaa 1140 accctcaaag gccaagctgt gcgcaaacag ctttgggaca cggccaacac ggtgaaggaa 1200 aagttcggga ggaagcttta tgaatcctta ctggttggga gccttcccga catgaacaag 1260 atgctggata aggaagactt cactatgatg aagagagcca tctttgcaac gcagcggcag 1320 tctttccccc ctgtgtgcac ccacaatatg ctggatgact cctcagaccc catcctgacc 1380 accatccgcc gaatcggcct cttcaatagc agtgccgaca gggtgaaggt gattttccac 1440 ccggagttcc tctcctccac aagccccctg ctccctgtgg actatgagga gtttgtccgt 1500 ggctgtcacc ttggagtctt cccctcctac tatgagcctt ggggctacac accggctgag 1560 tgcacggtta tgggaatccc cagtatctcc accaatctct ccggcttcgg ctgcttcatg 1620 gaggaacaca tcgcagaccc ctcagcttac ggtatctaca ttcttgaccg gcggttccgc 1680 agcctggatg attcctgctc gcagctcacc tccttcctct acagtttctg tcagcagagc 1740 cggcggcagc gtatcatcca gcggaaccgc acggagcgcc tctccgacct tctggactgg 1800 aaatacctag gccggtacta tatgtctgcg cgccacatgg cgctgtccaa ggcctttcca 1860 gagcacttca cctacgagcc caacgaggcg gatgcggccc aggggtaccg ctacccacgg 1920 ccagcctcgg tgccaccgtc gccctcgctg tcacgacact ccagcccgca ccagagtgag 1980 gacgaggagg atccccggaa cgggccgctg gaggaagacg gcgagcgcta cgatgaggac 2040 gaggaggccg ccaaggaccg gcgcaacatc cgtgcaccag agtggccgcg ccgagcgtcc 2100 tgcacctcct ccaccagcgg cagcaagcgc aactctgtgg acacggccac ctccagctca 2160 ctcagcaccc cgagcgagcc cctcagcccc accagctccc tgggcgagga gcgtaactaa 2220 gtccgcccca ccacactccc cgcctgtcct gcctctctgc tccagagaga ggatgcagag 2280 gggtgctgct cctaaacccc cgctccagat ctgcactggg tgtggccccg cagtgccccc 2340 acccagtccg ccaaacactc caccccctcc agctccagtt tccaagttcc tgcactccag 2400 aatccacaaa gccgtgcctt tctctggctc cagaatatgc ataatcagcg ccctggagtc 2460 ccctgggcct ggaccgcttc ccagaggcca ggaatctgcc attactctgc ggtggtgcca 2520 gaggttttag gaaacctggc atggtgcttt caggtctggg gcttttagag ccccccgtgt 2580 ggcttacaaa ttctacagca tacagagcag gccacgctca ggcccggcat gcgggccacc 2640 aagttctgga aaccacgtgg tgtccctgcg aatggggcga tcaagtccag agccggggca 2700 ctttcagagt ttgaaggtaa ctgagagcag atggtcctcc atttcaactc cagaagtggg 2760 gctctgggag ggatgttcta gccctccctg gcatgtcaga gccaggctct gcctggagga 2820 tccctccatc cggctcctgt catcccctac actttggcca agcaagaggt ggtagaacca 2880 cttggctgct cattccttct ggaggacaca cagtctcagt ccagatgcct tcctgtcttt 2940 ctggcccttt ctggaccaga tcctactctt cctttctaaa tctgagatct ccctccaggg 3000 aatccgcctg cagaggacag agctggctgt cttcccccac ccctaacctg gcttattccc 3060 aactgctctg cccactgtga aaccactagg ttctaggtcc tggcttctag atctggaacc 3120 ttaccacgtt actgcatact gatccctttc ccatgatcca gaactgaggt cactgggttc 3180 tagaaccccc acatttacct cgaggctctt ccatccccaa actgtgccct gccttcagct 3240 ttggtgaaag ggagggcccc tcatgtgtgc tgtgctgtgt ctgcaccgct tggtttgcag 3300 ttgagagggg agggcaggag gggtgtgatt ggagtgtgtc cggagatgag atgaaaaaaa 3360 tacatctata tttaagaaaa aaaaaaaaaa aaaa 3394 // |
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