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EBIDatabasesDatabase BrowsingDbfetch

EBI Dbfetch

ID   BC001138; SV 2; linear; mRNA; STD; HUM; 1440 BP.
XX
AC   BC001138;
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DT   09-MAR-2001 (Rel. 67, Created)
DT   15-OCT-2008 (Rel. 97, Last updated, Version 7)
XX
DE   Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone
DE   IMAGE:2989846), partial cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1440
RX   DOI; 10.1073/pnas.242603899
RX   PUBMED; 12477932.
RG   Mammalian Gene Collection Program Team
RA   Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D.,
RA   Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F.,
RA   Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H.,
RA   Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K.,
RA   Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F.,
RA   Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S.,
RA   Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J.,
RA   Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J.,
RA   Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M.,
RA   Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA   Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C.,
RA   Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I.,
RA   Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., Marra M.A.;
RT   "Generation and initial analysis of more than 15,000 full-length human and
RT   mouse cDNA sequences";
RL   Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).
XX
RN   [2]
RC   NIH-MGC Project URL: http://mgc.nci.nih.gov
RP   1-1440
RA   Strausberg R.;
RT   ;
RL   Submitted (11-DEC-2000) to the EMBL/GenBank/DDBJ databases.
RL   National Institutes of Health, Mammalian Gene Collection (MGC), Cancer
RL   Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03,
RL   Bethesda, MD 20892-2590, USA
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DR   ASTD; TRAN00000059124.
DR   Ensembl-Gn; ENSG00000213614; Homo_sapiens.
DR   Ensembl-Tr; ENST00000268097; Homo_sapiens.
DR   Ensembl-Tr; ENST00000423001; Homo_sapiens.
DR   Ensembl-Tr; ENST00000429918; Homo_sapiens.
DR   Ensembl-Tr; ENST00000457859; Homo_sapiens.
DR   H-InvDB; HIT000085962.
DR   ImaGenes; IMAGp958F2381Q.
DR   ImaGenes; IRALp962K163Q.
XX
CC   On Aug 19, 2003 this sequence version replaced gi:12654604.
CC   Contact: MGC help desk
CC   Email: cgapbs-r@mail.nih.gov
CC   Tissue Procurement: DCTD/DTP
CC   cDNA Library Preparation: Rubin Laboratory
CC   cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
CC   DNA Sequencing by: Institute for Systems Biology
CC   http://www.systemsbiology.org
CC   contact: amadan@systemsbiology.org
CC   Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
CC   Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
CC   Clone distribution: MGC clone distribution information can be found
CC   through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
CC   Series: IRAL Plate: 3 Row: k Column: 16.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1440
FT                   /organism="Homo sapiens"
FT                   /lab_host="DH10B-R"
FT                   /mol_type="mRNA"
FT                   /clone_lib="NIH_MGC_9"
FT                   /clone="IMAGE:2989846"
FT                   /tissue_type="Ovary, adenocarcinoma"
FT                   /note="Vector: pOTB7"
FT                   /db_xref="taxon:9606"
FT   gene            <1..1440
FT                   /gene="HEXA"
FT                   /note="synonym: TSD"
FT   CDS             <1..1231
FT                   /codon_start=2
FT                   /gene="HEXA"
FT                   /product="HEXA protein"
FT                   /db_xref="GOA:Q9BVJ8"
FT                   /db_xref="HGNC:4878"
FT                   /db_xref="HSSP:1NOW"
FT                   /db_xref="InterPro:IPR001540"
FT                   /db_xref="InterPro:IPR013781"
FT                   /db_xref="InterPro:IPR015882"
FT                   /db_xref="InterPro:IPR015883"
FT                   /db_xref="InterPro:IPR017853"
FT                   /db_xref="UniProtKB/TrEMBL:Q9BVJ8"
FT                   /protein_id="AAH01138.2"
FT                   /translation="NDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFP
FT                   RFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRK
FT                   GSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEP
FT                   SGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKK
FT                   GFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYM
FT                   KELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKALVIGGEACMW
FT                   GEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNV
FT                   GFCEQEFEQT"
FT   misc_feature    140..1105
FT                   /gene="HEXA"
FT                   /note="Glyco_hydro_20; Region: Glycosyl hydrolase family
FT                   20, catalytic domain. This domain has a TIM barrel fold"
XX
SQ   Sequence 1440 BP; 334 A; 355 C; 383 G; 368 T; 0 other;
     aaatgatgac cagtgtttac tcctctctga gactgtctgg ggagctctcc gaggtctgga        60
     gacttttagc cagcttgttt ggaaatctgc tgagggcaca ttctttatca acaagactga       120
     gattgaggac tttccccgct ttcctcaccg gggcttgctg ttggatacat ctcgccatta       180
     cctgccactc tctagcatcc tggacactct ggatgtcatg gcgtacaata aattgaacgt       240
     gttccactgg catctggtag atgatccttc cttcccatat gagagcttca cttttccaga       300
     gctcatgaga aaggggtcct acaaccctgt cacccacatc tacacagcac aggatgtgaa       360
     ggaggtcatt gaatacgcac ggctccgggg tatccgtgtg cttgcagagt ttgacactcc       420
     tggccacact ttgtcctggg gaccaggtat ccctggatta ctgactcctt gctactctgg       480
     gtctgagccc tctggcacct ttggaccagt gaatcccagt ctcaataata cctatgagtt       540
     catgagcaca ttcttcttag aagtcagctc tgtcttccca gatttttatc ttcatcttgg       600
     aggagatgag gttgatttca cctgctggaa gtccaaccca gagatccagg actttatgag       660
     gaagaaaggc ttcggtgagg acttcaagca gctggagtcc ttctacatcc agacgctgct       720
     ggacatcgtc tcttcttatg gcaagggcta tgtggtgtgg caggaggtgt ttgataataa       780
     agtaaagatt cagccagaca caatcataca ggtgtggcga gaggatattc cagtgaacta       840
     tatgaaggag ctggaattgg tcaccaaggc cggcttccgg gcccttctct ctgccccctg       900
     gtacctgaac cgtatatcct atggccctga ctggaaggat ttctacgtag tggaacccct       960
     ggcatttgaa ggtacccctg agcagaaggc tctggtgatt ggtggagagg cttgtatgtg      1020
     gggagaatat gtggacaaca caaacctggt ccccaggctc tggcccagag caggggctgt      1080
     tgccgaaagg ctgtggagca acaagttgac atctgacctg acatttgcct atgaacgttt      1140
     gtcacacttc cgctgtgagt tgctgaggcg aggtgtccag gcccaacccc tcaatgtagg      1200
     cttctgtgag caggagtttg aacagacctg agccccaggc accgaggagg gtgctggctg      1260
     taggtgaatg gtagtggagc caggcttcca ctgcatcctg gccaggggac ggagcccctt      1320
     gccttcgtgc cccttgcctg cgtgcccctg tgcttggaga gaaaggggcc ggtgctggcg      1380
     ctcgcattca ataaagagta atgtggcatt tttctataat aaaaaaaaaa aaaaaaaaaa      1440
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